Skip to main content

Research

Research grants

Development of non-covalent binders to SOD1 with scope for developing as PROTAC degraders of SOD1 for the treatment of MND

MOTOR NEURONE DISEASE ASSOCIATION (UK)

October 2023 - January 2027

Towards a paradigm shift in understanding of membrane-bound Nitric Oxide reductase and its complexes with the electron donor and NO-producing enzyme

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

November 2023 - November 2026

Characterisation of novel cardiac troponin I mutants associated with human hypertrophic cardiomyopathy

BRITISH HEART FOUNDATION (UK)

December 2021 - November 2024

A new generation of Crystallographic detector for Multi-user Barkla X-ray laboratory

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

July 2017 - July 2018

Damage Free structures of quinol dependent nitric oxide reductase (qNOR) in complex with nitrite reductase (NiR) from A. xylosoxidans

SCIENCE AND TECHNOLOGY FACILITIES COUNCIL

September 2015 - September 2019

Why does Nature use modular enzyme architectures for biological catalysis

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

January 2017 - July 2020

Structure-function studies of faulty proteins and their complexes involved in motor neuron disease

MOTOR NEURONE DISEASE ASSOCIATION

October 2015 - September 2018

2014 allocation - Wellcome ISSF non clinical fellowships

WELLCOME TRUST (UK)

May 2015 - October 2018

The cause and effect of SOD1 destabilization on motor neuron disease

MEDICAL RESEARCH FOUNDATION (UK)

October 2015 - April 2019

Proteins involved in Neurodegeneration

SOCIETE CIVILE SYNCHROTRON SOLEIL (FRANCE)

October 2014 - September 2017

TDP-43 and the molecular causes of its pathogenicity in neurodegenerative disease

MOTOR NEURONE DISEASE ASSOCIATION

October 2011 - February 2015

Transient and Stable Macromolecular complexes formed by Denitrifying Enzymes

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

June 2014 - June 2019

New challenges of Structural biology arising from the emergence of brilliant X-ray beams from X-ray Lasers

SCIENCE AND TECHNOLOGY FACILITIES COUNCIL

July 2014 - June 2018

YEAR 1 Wellcome Trust ISSF Non-Clinical Fellowships

WELLCOME TRUST (UK)

October 2011 - May 2018

Structural studies of proteins related to liver disease

CIC BIOGUNE (SPAIN)

September 2011 - August 2015

    Research collaborations

    John Collinge

    MRC Centre for Neurodegeneration Research

    Structural studies of human prion protein.