Research outputs
2025
Complying with ARRIVE 2.0: Reporting essentials for animal models of envenoming therapeutic efficacy testing
Marriott, A. E., & Ainsworth, S. (2025). Complying with ARRIVE 2.0: Reporting essentials for animal models of envenoming therapeutic efficacy testing. TOXICON, 268. doi:10.1016/j.toxicon.2025.108628
Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites
Ahmadi, S., Burlet, N. J., Benard-Valle, M., Guadarrama-Martinez, A., Kerwin, S., Cardoso, I. A., . . . Laustsen, A. H. (2025). Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites. NATURE, 647(8090). doi:10.1038/s41586-025-09661-0
Preclinical evaluation of the neutralising efficacy of three antivenoms against the venoms of the recently taxonomically partitioned <i>E. ocellatus</i> and <i>E. romani</i>
Edge, R. J., Marriott, A. E., Keen, M., Xie, T., Crittenden, E. P., Dawson, C. A., . . . Menzies, S. K. (2025). Preclinical evaluation of the neutralising efficacy of three antivenoms against the venoms of the recently taxonomically partitioned <i>E. ocellatus</i> and <i>E. romani</i>. PLOS NEGLECTED TROPICAL DISEASES, 19(8). doi:10.1371/journal.pntd.0013371
Shotgun metagenomic analysis of the oral microbiomes of children with noma reveals a novel disease-associated organism
Primary health system strengthening and system-level interventions for tackling snakebite envenoming in India
Kadam, P., Ainsworth, S., & Patel, B. (2025). Primary health system strengthening and system-level interventions for tackling snakebite envenoming in India. TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 119(6), 635-637. doi:10.1093/trstmh/trae106
Practical progress towards the development of recombinant antivenoms for snakebite envenoming
Menzies, S. K., Patel, R. N., & Ainsworth, S. (2025). Practical progress towards the development of recombinant antivenoms for snakebite envenoming. EXPERT OPINION ON DRUG DISCOVERY, 20(6), 799-819. doi:10.1080/17460441.2025.2495943
2024
Genomic and taxonomic evaluation of 38 Treponema prophage sequences.
Ridgway, R., Lu, H., Blower, T. R., Evans, N. J., & Ainsworth, S. (2024). Genomic and taxonomic evaluation of 38 Treponema prophage sequences.. BMC genomics, 25(1), 549. doi:10.1186/s12864-024-10461-5
Intraspecific venom variation in the medically important puff adder (<i>Bitis arietans</i>): Comparative venom gland transcriptomics, <i>in vitro</i> venom activity and immunological recognition by antivenom
Dawson, C. A., Bartlett, K. E., Wilkinson, M. C., Ainsworth, S., Albulescu, L. -O., Kazandijan, T., . . . Casewell, N. R. (2024). Intraspecific venom variation in the medically important puff adder (<i>Bitis arietans</i>): Comparative venom gland transcriptomics, <i>in vitro</i> venom activity and immunological recognition by antivenom. PLOS NEGLECTED TROPICAL DISEASES, 18(10). doi:10.1371/journal.pntd.0012570
Plug and play virus-like particles for the generation of anti-toxin antibodies
Edge, R. J., Marriott, A. E., Stars, E. L., Patel, R. N., Wilkinson, M. C., King, L. D. W., . . . Ainsworth, S. (2024). Plug and play virus-like particles for the generation of anti-toxin antibodies. TOXICON-X, 23. doi:10.1016/j.toxcx.2024.100204
Progress on improving animal welfare and experiment translatability using an animal model of venom induced consumption coagulopathy
Marriott, A. E., Stars, E., Casewell, N., & Ainsworth, S. (2024). Progress on improving animal welfare and experiment translatability using an animal model of venom induced consumption coagulopathy. Toxicon, 248, 107924. doi:10.1016/j.toxicon.2024.107924
Handheld point-of-care devices for snakebite coagulopathy: a scoping review.
Abouyannis, M., Marriott, A. E., Stars, E., Kitchen, D. P., Kitchen, S., Woods, T. A. L., . . . Casewell, N. R. (2024). Handheld point-of-care devices for snakebite coagulopathy: a scoping review.. Thrombosis and haemostasis. doi:10.1055/a-2407-1400
Reported snakebite mortality and state compensation payments in Madhya Pradesh, India, from 2020 to 2022.
Kadam, P., Patel, B., Gopalakrishnan, M., Sirur, F. M., Bharti, O. K., Agrawal, A., . . . Ainsworth, S. (2024). Reported snakebite mortality and state compensation payments in Madhya Pradesh, India, from 2020 to 2022.. Transactions of the Royal Society of Tropical Medicine and Hygiene, trae045. doi:10.1093/trstmh/trae045
Noma finally recognised as a neglected tropical disease.
Ainsworth, S. (2024). Noma finally recognised as a neglected tropical disease.. PLoS neglected tropical diseases, 18(5), e0012177. doi:10.1371/journal.pntd.0012177
Improving <i>in vivo</i> assays in snake venom and antivenom research: A community discussion.
Marriott, A. E., Casewell, N. R., Lilley, E., Gutiérrez, J. -M., & Ainsworth, S. (2024). Improving <i>in vivo</i> assays in snake venom and antivenom research: A community discussion.. F1000Research, 13, 192. doi:10.12688/f1000research.148223.1
African polyvalent antivenom can maintain pharmacological stability and ability to neutralise murine venom lethality for decades post-expiry: evidence for increasing antivenom shelf life to aid in alleviating chronic shortages.
Solano, G., Cunningham, S., Edge, R. J., Duran, G., Sanchez, A., Villalta, M., . . . Ainsworth, S. (2024). African polyvalent antivenom can maintain pharmacological stability and ability to neutralise murine venom lethality for decades post-expiry: evidence for increasing antivenom shelf life to aid in alleviating chronic shortages.. BMJ global health, 9(3), e014813. doi:10.1136/bmjgh-2023-014813
Analysis of commercially available snake antivenoms reveals high contents of endotoxins in some products.
Solano, G., Ainsworth, S., Sánchez, A., Villalta, M., Sánchez, P., Durán, G., . . . León, G. (2024). Analysis of commercially available snake antivenoms reveals high contents of endotoxins in some products.. Toxicon: X, 21, 100187. doi:10.1016/j.toxcx.2024.100187
Characterisation of Putative Outer Membrane Proteins from Leptospira borgpetersenii Serovar Hardjo-Bovis Identifies Novel Adhesins and Diversity in Adhesion across Genomospecies Orthologs
Kamaruzaman, I. N. A., Staton, G. J., Ainsworth, S., Carter, S. D., & Evans, N. J. (2024). Characterisation of Putative Outer Membrane Proteins from Leptospira borgpetersenii Serovar Hardjo-Bovis Identifies Novel Adhesins and Diversity in Adhesion across Genomospecies Orthologs. Microorganisms, 12(2), 245. doi:10.3390/microorganisms12020245
Improving in vivo assays in snake venom and antivenom research: A community discussion
Marriott, A., Casewell, N., Lilley, E., Gutiérrez, J. -M., & Ainsworth, S. (2024). Improving in vivo assays in snake venom and antivenom research: A community discussion. doi:10.12688/f1000research.148223.1
Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins
Khalek, I. S., Laxme, R. R. S., Nguyen, Y. T. K., Khochare, S., Patel, R. N., Woehl, J., . . . Jardine, J. G. (2024). Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins. SCIENCE TRANSLATIONAL MEDICINE, 16(735). doi:10.1126/scitranslmed.adk1867
2023
OC 78.5 Systemic Snakebite Envenoming Causes Histone-Induced Thrombocytopaenia
Schofield, J., Abrams, S., Alhamdi, Y., Ainsworth, S., Evans, C., Albulescu, L., . . . Toh, C. (2023). OC 78.5 Systemic Snakebite Envenoming Causes Histone-Induced Thrombocytopaenia. Research and Practice in Thrombosis and Haemostasis, 7, 100487. doi:10.1016/j.rpth.2023.100487
2022
Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition
Menzies, S. K., Dawson, C. A., Crittenden, E., Edge, R. J., Hall, S. R., Alsolaiss, J., . . . Ainsworth, S. (2022). Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition. SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-13376-x
Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms
Alomran, N., Blundell, P., Alsolaiss, J., Crittenden, E., Ainsworth, S., Dawson, C. A., . . . Casewell, N. R. (2022). Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms. TOXINS, 14(7). doi:10.3390/toxins14070443
Correction: Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically diverse snake venoms.
Alomran, N., Alsolaiss, J., Albulescu, L. -O., Crittenden, E., Harrison, R. A., Ainsworth, S., & Casewell, N. R. (2022). Correction: Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically diverse snake venoms.. PLoS neglected tropical diseases, 16(6), e0010511. doi:10.1371/journal.pntd.0010511
Exploring the utility of recombinantly expressed snake venom serine protease toxins as immunogens for generating experimental snakebite antivenoms
2021
A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite (vol 11, 6094, 2020)
Albulescu, L. -O., Xie, C., Ainsworth, S., Alsolaiss, J., Crittenden, E., Dawson, C. A., . . . Casewell, N. R. (2021). A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite (vol 11, 6094, 2020). NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-24308-0
Corrigendum to: The new COST Action European Venom Network (EUVEN)-synergy and future perspectives of modern venomics.
Modica, M. V., Ahmad, R., Ainsworth, S., Anderluh, G., Antunes, A., Beis, D., . . . Zancolli, G. (2021). Corrigendum to: The new COST Action European Venom Network (EUVEN)-synergy and future perspectives of modern venomics.. GigaScience, 10(12), giab102. doi:10.1093/gigascience/giab102
Welcome to online-only production of <i>Parasitology</i> and future-proofing of the journal's academic standards
Stothard, J. R., Ainsworth, S., & Marriott, A. E. (2021). Welcome to online-only production of <i>Parasitology</i> and future-proofing of the journal's academic standards. PARASITOLOGY, 148(13), 1529-1531. doi:10.1017/S003118202100144X
Virus-like particles displaying conserved toxin epitopes stimulate broadly reactive, polyspecific, murine antibody responses capable of snake venom recognition
Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the <i>in vitro</i> cross-reactivity and <i>in vivo</i> neutralisation of geographically diverse snake venoms
Alomran, N., Alsolaiss, J., Albulescu, L. -O., Crittenden, E., Harrison, R. A., Ainsworth, S., & Casewell, N. R. (2021). Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the <i>in vitro</i> cross-reactivity and <i>in vivo</i> neutralisation of geographically diverse snake venoms. PLOS NEGLECTED TROPICAL DISEASES, 15(8). doi:10.1371/journal.pntd.0009659
Hexapod Assassins' Potion: Venom Composition and Bioactivity from the Eurasian Assassin Bug <i>Rhynocoris iracundus</i>
Rugen, N., Jenkins, T. P., Wielsch, N., Vogel, H., Hempel, B. -F., Suessmuth, R. D., . . . Tonk, M. (2021). Hexapod Assassins' Potion: Venom Composition and Bioactivity from the Eurasian Assassin Bug <i>Rhynocoris iracundus</i>. BIOMEDICINES, 9(7). doi:10.3390/biomedicines9070819
Snake Venom Metalloproteinases
Dawson, C. A., Ainsworth, S., Albulescu, L. -O., & Casewell, N. R. (2021). Snake Venom Metalloproteinases. In Handbook of Venoms and Toxins of Reptiles (pp. 363-380). CRC Press. doi:10.1201/9780429054204-28
Dissecting the molecular diversity and commonality of bovine and human treponemes identifies key survival and adhesion mechanisms
Staton, G. J., Clegg, S. R., Ainsworth, S., Armstrong, S., Carter, S. D., Radford, A. D., . . . Evans, N. J. (2021). Dissecting the molecular diversity and commonality of bovine and human treponemes identifies key survival and adhesion mechanisms. PLOS PATHOGENS, 17(3). doi:10.1371/journal.ppat.1009464
The new COST Action European Venom Network (EUVEN)-synergy and future perspectives of modern venomics.
Modica, M. V., Ahmad, R., Ainsworth, S., Anderluh, G., Antunes, A., Beis, D., . . . Zancolli, G. (2021). The new COST Action European Venom Network (EUVEN)-synergy and future perspectives of modern venomics.. GigaScience, 10(3), giab019. doi:10.1093/gigascience/giab019
Approaches for implementing society-led community interventions to mitigate snakebite envenoming burden: The SHE-India experience
Kadam, P., Ainsworth, S., Sirur, F. M., Patel, D. C., Kuruvilla, J. J., & Majumdar, D. B. (2021). Approaches for implementing society-led community interventions to mitigate snakebite envenoming burden: The SHE-India experience. PLOS NEGLECTED TROPICAL DISEASES, 15(2). doi:10.1371/journal.pntd.0009078
Convergent evolution of pain-inducing defensive venom components in spitting cobras
Kazandjian, T. D., Petras, D., Robinson, S. D., van Thiel, J., Greene, H. W., Arbuckle, K., . . . Casewell, N. R. (2021). Convergent evolution of pain-inducing defensive venom components in spitting cobras. SCIENCE, 371(6527), 386-+. doi:10.1126/science.abb9303
Animal derived antibodies should be considered alongside convalescent human plasma to deliver treatments for COVID-19
Ainsworth, S., Menzies, S., & Pleass, R. (2020). Animal derived antibodies should be considered alongside convalescent human plasma to deliver treatments for COVID-19. doi:10.12688/wellcomeopenres.15990.1
2020
A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite
Albulescu, L. -O., Xie, C., Ainsworth, S., Alsolaiss, J., Crittenden, E., Dawson, C. A., . . . Casewell, N. R. (2020). A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite. NATURE COMMUNICATIONS, 11(1). doi:10.1038/s41467-020-19981-6
Differences in the antibody response to adult Fasciola hepatica excretory/secretory products in experimentally and naturally infected cattle and sheep
Walsh, T. R., Ainsworth, S., Armstrong, S., Hodgkinson, J., & Williams, D. (2020). Differences in the antibody response to adult Fasciola hepatica excretory/secretory products in experimentally and naturally infected cattle and sheep. Veterinary Parasitology, 109321. doi:10.1016/j.vetpar.2020.109321
An analysis of preclinical efficacy testing of antivenoms for sub-Saharan Africa: Inadequate independent scrutiny and poor-quality reporting are barriers to improving snakebite treatment and management
Ainsworth, S., Menzies, S. K., Casewell, N. R., & Harrison, R. A. (2020). An analysis of preclinical efficacy testing of antivenoms for sub-Saharan Africa: Inadequate independent scrutiny and poor-quality reporting are barriers to improving snakebite treatment and management. PLOS NEGLECTED TROPICAL DISEASES, 14(8). doi:10.1371/journal.pntd.0008579
Correction: Preclinical antivenom-efficacy testing reveals potentially disturbing deficiencies of snakebite treatment capability in East Africa.
Harrison, R. A., Oluoch, G. O., Ainsworth, S., Alsolaiss, J., Bolton, F., Arias, A. -S., . . . Casewell, N. R. (2020). Correction: Preclinical antivenom-efficacy testing reveals potentially disturbing deficiencies of snakebite treatment capability in East Africa.. PLoS neglected tropical diseases, 14(8), e0008698. doi:10.1371/journal.pntd.0008698
Convergent Evolution of Pain-Inducing Defensive Venom Components in Spitting Cobras
An interactive database for the investigation of high-density peptide microarray guided interaction patterns and antivenom cross-reactivity.
Krause, K. E., Jenkins, T. P., Skaarup, C., Engmark, M., Casewell, N. R., Ainsworth, S., . . . Laustsen, A. H. (2020). An interactive database for the investigation of high-density peptide microarray guided interaction patterns and antivenom cross-reactivity.. PLoS neglected tropical diseases, 14(6), e0008366. doi:10.1371/journal.pntd.0008366
Editorial: Novel Immunotherapies Against Envenomings by Snakes and Other Venomous Animals.
Laustsen, A. H., Ainsworth, S., Lomonte, B., Kini, R. M., & Chávez-Olórtegui, C. (2020). Editorial: Novel Immunotherapies Against Envenomings by Snakes and Other Venomous Animals.. Frontiers in immunology, 11, 1004. doi:10.3389/fimmu.2020.01004
A therapeutic combination of two small molecule toxin inhibitors provides pancontinental preclinical efficacy against viper snakebite
Preclinical validation of a repurposed metal chelator as an early-intervention therapeutic for hemotoxic snakebite
Albulescu, L. -O., Hale, M. S., Ainsworth, S., Alsolaiss, J., Crittenden, E., Calvete, J. J., . . . Casewell, N. R. (2020). Preclinical validation of a repurposed metal chelator as an early-intervention therapeutic for hemotoxic snakebite. SCIENCE TRANSLATIONAL MEDICINE, 12(542). doi:10.1126/scitranslmed.aay8314
Putative β-Barrel Outer Membrane Proteins of the Bovine Digital Dermatitis-Associated Treponemes: Identification, Functional Characterization, and Immunogenicity
Staton, G. J., Carter, S. D., Ainsworth, S., Mullin, J., Smith, R. F., & Evans, N. J. (2020). Putative β-Barrel Outer Membrane Proteins of the Bovine Digital Dermatitis-Associated Treponemes: Identification, Functional Characterization, and Immunogenicity. INFECTION AND IMMUNITY, 88(5). doi:10.1128/IAI.00050-20
CONVERGENT EVOLUTION OF DEFENSIVE VENOM COMPONENTS IN SPITTING COBRAS
Kazandjian, T., Petras, D., Robinson, S., Undheim, E., Arbuckle, K., Whiteley, G., . . . Casewell, N. (2020). CONVERGENT EVOLUTION OF DEFENSIVE VENOM COMPONENTS IN SPITTING COBRAS. TOXICON, 177, S37. Retrieved from https://www.webofscience.com/
CROSS-SPECIES AND GEOGRAPHIC POTENTIAL OF B-CELL EPITOPE STRINGS IDENTIFIED FOR GENERATION OF AN AFRICA-SPECIFIC SNAKE VENOM-INDUCED NECROSIS THERAPEUTIC
Dawson, C., Ainsworth, S., Wilkinson, M., & Harrison, R. (2020). CROSS-SPECIES AND GEOGRAPHIC POTENTIAL OF B-CELL EPITOPE STRINGS IDENTIFIED FOR GENERATION OF AN AFRICA-SPECIFIC SNAKE VENOM-INDUCED NECROSIS THERAPEUTIC. TOXICON, 177, S34-S35. Retrieved from https://www.webofscience.com/
Snake Venom Gland Organoids
Post, Y., Puschhof, J., Beumer, J., Kerkkamp, H. M., de Bakker, M. A. G., Slagboom, J., . . . Clevers, H. (2020). Snake Venom Gland Organoids. CELL, 180(2), 233-+. doi:10.1016/j.cell.2019.11.038
2019
The time is now: a call for action to translate recent momentum on tackling tropical snakebite into sustained benefit for victims
Harrison, R. A., Casewell, N. R., Ainsworth, S. A., & Lalloo, D. G. (2019). The time is now: a call for action to translate recent momentum on tackling tropical snakebite into sustained benefit for victims. TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 113(12), 834-837. doi:10.1093/trstmh/try134
Preclinical validation of a repurposed metal chelator as a community-based therapeutic for hemotoxic snakebite
Strategy for a globally coordinated response to a priority neglected tropical disease: Snakebite envenoming
Williams, D. J., Abul Faiz, M., Abela-Ridder, B., Ainsworth, S., Bulfone, T. C., Nickerson, A. D., . . . Warrell, D. A. (2019). Strategy for a globally coordinated response to a priority neglected tropical disease: Snakebite envenoming. PLOS NEGLECTED TROPICAL DISEASES, 13(2). doi:10.1371/journal.pntd.0007059
A Decoy-Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite
Albulescu, L. -O., Kazandjian, T., Slagboom, J., Bruyneel, B., Ainsworth, S., Alsolaiss, J., . . . Casewell, N. R. (2019). A Decoy-Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite. FRONTIERS IN PHARMACOLOGY, 10. doi:10.3389/fphar.2019.00848
2018
The paraspecific neutralisation of snake venom induced coagulopathy by antivenoms
Ainsworth, S., Slagboom, J., Alomran, N., Pla, D., Alhamdi, Y., King, S. I., . . . Casewell, N. R. (2018). The paraspecific neutralisation of snake venom induced coagulopathy by antivenoms. COMMUNICATIONS BIOLOGY, 1. doi:10.1038/s42003-018-0039-1
Rapid ligand fishing for identification of acetylcholinesterase-binding peptides in snake venom reveals new properties of dendrotoxins
Vanzolini, K. L., Ainsworth, S., Bruyneel, B., Herzig, V., Seraus, M. G. L., Somsen, G. W., . . . Kool, J. (2018). Rapid ligand fishing for identification of acetylcholinesterase-binding peptides in snake venom reveals new properties of dendrotoxins. TOXICON, 152, 1-8. doi:10.1016/j.toxicon.2018.06.080
The medical threat of mamba envenoming in sub-Saharan Africa revealed by genus-wide analysis of venom composition, toxicity and antivenomics profiling of available antivenoms
Ainsworth, S., Petras, D., Engmark, M., Suessmuth, R. D., Whiteley, G., Albulescu, L. -O., . . . Calvete, J. J. (2018). The medical threat of mamba envenoming in sub-Saharan Africa revealed by genus-wide analysis of venom composition, toxicity and antivenomics profiling of available antivenoms. JOURNAL OF PROTEOMICS, 172, 173-189. doi:10.1016/j.jprot.2017.08.016
2017
Preclinical antivenom-efficacy testing reveals potentially disturbing deficiencies of snakebite treatment capability in East Africa
Harrison, R. A., Oluoch, G. O., Ainsworth, S., Alsolaiss, J., Bolton, F., Arias, A. -S., . . . Casewell, N. R. (2017). Preclinical antivenom-efficacy testing reveals potentially disturbing deficiencies of snakebite treatment capability in East Africa. PLOS NEGLECTED TROPICAL DISEASES, 11(10). doi:10.1371/journal.pntd.0005969
Another Brick in the Wall: a Rhamnan Polysaccharide Trapped inside Peptidoglycan of <i>Lactococcus lactis</i>
Sadovskaya, I., Vinogradov, E., Courtin, P., Armalyte, J., Meyrand, M., Giaouris, E., . . . Chapot-Chartier, M. -P. (2017). Another Brick in the Wall: a Rhamnan Polysaccharide Trapped inside Peptidoglycan of <i>Lactococcus lactis</i>. MBIO, 8(5). doi:10.1128/mBio.01303-17
2016
Isolation of digital dermatitis treponemes from cattle hock skin lesions
Clegg, S. R., Bell, J., Ainsworth, S., Blowey, R. W., Bell, N. J., Carter, S. D., & Evans, N. J. (2016). Isolation of digital dermatitis treponemes from cattle hock skin lesions. VETERINARY DERMATOLOGY, 27(2), 106-E30. doi:10.1111/vde.12286
2015
Ligneous membranitis in Scottish Terriers is associated with a single nucleotide polymorphism in the <i>plasminogen</i> (<i>PLG</i>) gene
Ainsworth, S., Carter, S., Fisher, C., Dawson, J., Makrides, L., Nuttall, T., & Mason, S. L. (2015). Ligneous membranitis in Scottish Terriers is associated with a single nucleotide polymorphism in the <i>plasminogen</i> (<i>PLG</i>) gene. ANIMAL GENETICS, 46(6), 707-710. doi:10.1111/age.12339
2014
The <i>Lactococcus lactis</i> plasmidome: much learnt, yet still lots to discover
Ainsworth, S., Stockdale, S., Bottacini, F., Mahony, J., & van Sinderen, D. (2014). The <i>Lactococcus lactis</i> plasmidome: much learnt, yet still lots to discover. FEMS MICROBIOLOGY REVIEWS, 38(5), 1066-1088. doi:10.1111/1574-6976.12074
Differences in Lactococcal Cell Wall Polysaccharide Structure Are Major Determining Factors in Bacteriophage Sensitivity
Ainsworth, S., Sadovskaya, I., Vinogradov, E., Courtin, P., Guerardel, Y., Mahony, J., . . . van Sinderen, D. (2014). Differences in Lactococcal Cell Wall Polysaccharide Structure Are Major Determining Factors in Bacteriophage Sensitivity. MBIO, 5(3). doi:10.1128/mBio.00880-14
The Plasmid Complement of <i>Lactococcus lactis</i> UC509.9 Encodes Multiple Bacteriophage Resistance Systems
Ainsworth, S., Mahony, J., & van Sinderen, D. (2014). The Plasmid Complement of <i>Lactococcus lactis</i> UC509.9 Encodes Multiple Bacteriophage Resistance Systems. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80(14), 4341-4349. doi:10.1128/AEM.01070-14
2013
Bacteriophage Orphan DNA Methyltransferases: Insights from Their Bacterial Origin, Function, and Occurrence
Murphy, J., Mahony, J., Ainsworth, S., Nauta, A., & van Sinderen, D. (2013). Bacteriophage Orphan DNA Methyltransferases: Insights from Their Bacterial Origin, Function, and Occurrence. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 79(24), 7547-7555. doi:10.1128/AEM.02229-13
Lytic Infection of <i>Lactococcus lactis</i> by Bacteriophages Tuc2009 and c2 Triggers Alternative Transcriptional Host Responses
Ainsworth, S., Zomer, A., Mahony, J., & van Sinderen, D. (2013). Lytic Infection of <i>Lactococcus lactis</i> by Bacteriophages Tuc2009 and c2 Triggers Alternative Transcriptional Host Responses. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 79(16), 4786-4798. doi:10.1128/AEM.01197-13
Tale of the unseen phage
Mahony, J., Ainsworth, S., & van Sinderen, D. (2013). Tale of the unseen phage. Bacteriophage, 3(3), e25985. doi:10.4161/bact.25985
Investigation of the Relationship between Lactococcal Host Cell Wall Polysaccharide Genotype and 936 Phage Receptor Binding Protein Phylogeny
Mahony, J., Kot, W., Murphy, J., Ainsworth, S., Neve, H., Hansen, L. H., . . . van Sinderen, D. (2013). Investigation of the Relationship between Lactococcal Host Cell Wall Polysaccharide Genotype and 936 Phage Receptor Binding Protein Phylogeny. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 79(14), 4385-4392. doi:10.1128/AEM.00653-13
Complete Genome of Lactococcus lactis subsp. cremoris UC509.9, Host for a Model Lactococcal P335 Bacteriophage.
Ainsworth, S., Zomer, A., de Jager, V., Bottacini, F., van Hijum, S. A. F. T., Mahony, J., & van Sinderen, D. (2013). Complete Genome of Lactococcus lactis subsp. cremoris UC509.9, Host for a Model Lactococcal P335 Bacteriophage.. Genome announcements, 1(1), e00119-e00112. doi:10.1128/genomea.00119-12
2012
Phages of lactic acid bacteria: The role of genetics in understanding phage-host interactions and their co-evolutionary processes
Mahony, J., Ainsworth, S., Stockdale, S., & van Sinderen, D. (2012). Phages of lactic acid bacteria: The role of genetics in understanding phage-host interactions and their co-evolutionary processes. VIROLOGY, 434(2), 143-150. doi:10.1016/j.virol.2012.10.008