Research outputs
2022
<i>Plasmodium falciparum</i> GBP2 is a telomere-associated protein that binds to G-quadruplex DNA and RNA
Edwards-Smallbone, J., Jensen, A. L., Roberts, L. E., Totanes, F. I. G., Hart, S. R., & Merrick, C. J. (2022). <i>Plasmodium falciparum</i> GBP2 is a telomere-associated protein that binds to G-quadruplex DNA and RNA. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 12. doi:10.1101/2021.07.02.450898
<i>Plasmodium falciparum</i> GBP2 Is a Telomere-Associated Protein That Binds to G-Quadruplex DNA and RNA.
Edwards-Smallbone, J., Jensen, A. L., Roberts, L. E., Totañes, F. I. G., Hart, S. R., & Merrick, C. J. (2022). <i>Plasmodium falciparum</i> GBP2 Is a Telomere-Associated Protein That Binds to G-Quadruplex DNA and RNA.. Frontiers in cellular and infection microbiology, 12, 782537. doi:10.3389/fcimb.2022.782537
2020
Safe nanoengineering and incorporation of transplant populations in a neurosurgical grade biomaterial, DuraGen Plus™, for protected cell therapy applications
Finch, L., Harris, S., Solomou, G., Sen, J., Tzerakis, N., Emes, R. D., . . . Chari, D. M. (2020). Safe nanoengineering and incorporation of transplant populations in a neurosurgical grade biomaterial, DuraGen Plus™, for protected cell therapy applications. JOURNAL OF CONTROLLED RELEASE, 321, 553-563. doi:10.1016/j.jconrel.2020.02.028
2018
Coupling Plant-Derived Cyclotides to Metal Surfaces: An Antibacterial and Antibiofilm Study
Cao, P., Yang, Y., Uche, F. I., Hart, S. R., Li, W. -W., & Yuan, C. (2018). Coupling Plant-Derived Cyclotides to Metal Surfaces: An Antibacterial and Antibiofilm Study. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19(3). doi:10.3390/ijms19030793
Using bioinformatics for the identification of key peptides to engineer dopamine neurons. Towards a therapy for Parkinson’s disease.
A proteomic investigation into mechanisms underpinning corticosteroid effects on neural stem cells
Al-Mayyahi, R. S., Sterio, L. D., Connolly, J. B., Adams, C. F., Al-Tumah, W. A., Sen, J., . . . Chari, D. M. (2018). A proteomic investigation into mechanisms underpinning corticosteroid effects on neural stem cells. MOLECULAR AND CELLULAR NEUROSCIENCE, 86, 30-40. doi:10.1016/j.mcn.2017.11.006
2017
Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer
de Wolf, E., Abdullah, M. I., Jones, S. M., Menezes, K., Moss, D. M., Drijfhout, F. P., . . . Richardson, A. (2017). Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-05595-4
2016
Fluorescent liquid pyrene derivative-in-water microemulsions
Hollamby, M. J., Danks, A. E., Schnepp, Z., Rogers, S. E., Hart, S. R., & Nakanishi, T. (2016). Fluorescent liquid pyrene derivative-in-water microemulsions. CHEMICAL COMMUNICATIONS, 52(46), 7344-7347. doi:10.1039/c6cc01517d
2015
Electron transfer dissociation of native peptides facilitates enhanced identification of urinary peptides
Hart, S. R., Kenny, L. C., Myers, J. E., & Baker, P. N. (2015). Electron transfer dissociation of native peptides facilitates enhanced identification of urinary peptides. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 391, 41-46. doi:10.1016/j.ijms.2015.08.025
[203-POS]
Hart, S., Kenny, L., Myers, J., & Baker, P. (2015). [203-POS]. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 5(1), 102. doi:10.1016/j.preghy.2014.10.209
[82-OR]
Hart, S., Kenny, L., Myers, J., & Baker, P. (2015). [82-OR]. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 5(1), 44-45. doi:10.1016/j.preghy.2014.10.086
2011
Distributions of Ion Series in ETD and CID Spectra: Making a Comparison
Hart, S. R., Lau, K. W., Gaskell, S. J., & Hubbard, S. J. (2011). Distributions of Ion Series in ETD and CID Spectra: Making a Comparison. DATA MINING IN PROTEOMICS: FROM STANDARDS TO APPLICATIONS, 696, 327-337. doi:10.1007/978-1-60761-987-1_21
2010
A Protocol for Top-Down Proteomics Using HPLC and ETD/PTR-MS
Hart, S. R. (2010). A Protocol for Top-Down Proteomics Using HPLC and ETD/PTR-MS. LC-MS/MS IN PROTEOMICS: METHODS AND APPLICATIONS, 658, 339-353. doi:10.1007/978-1-60761-780-8_21
2009
Observations on the detection of b- and y-type ions in the collisionally activated decomposition spectra of protonated peptides
Lau, K. W., Hart, S. R., Lynch, J. A., Wong, S. C. C., Hubbard, S. J., & Gaskell, S. J. (2009). Observations on the detection of b- and y-type ions in the collisionally activated decomposition spectra of protonated peptides. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 23(10), 1508-1514. doi:10.1002/rcm.4032
Analysis of the Trypanosome Flagellar Proteome Using a Combined Electron Transfer/Collisionally Activated Dissociation Strategy
Hart, S. R., Lau, K. W., Hao, Z., Broadhead, R., Portman, N., Huehmer, A., . . . Gaskell, S. J. (2009). Analysis of the Trypanosome Flagellar Proteome Using a Combined Electron Transfer/Collisionally Activated Dissociation Strategy. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 20(2), 167-175. doi:10.1016/j.jasms.2008.08.014
2008
Methods of proteome analysis: challenges and opportunities.
Hart, S. R., & Gaskell, S. J. (2008). Methods of proteome analysis: challenges and opportunities.. SEB experimental biology series, 61, 37-64.
2007
Proteomic analysis of the adaptation of the host NSO myeloma cell line to a protein-free medium
De La Luz-Hernández, K. R., Rojas-Del Calvo, L., Victores-Sarasola, S., Lage-Castellanos, A., Eyers, C., Hart, S., . . . Gaskell, S. (2007). Proteomic analysis of the adaptation of the host NSO myeloma cell line to a protein-free medium. Biotecnologia Aplicada, 24(3-4), 215-223.
Pride Wizard: generation of standards compliant quantitative proteomics data
Swainston, N., Siepen, J. A., Jones, A. R., Hart, S. R., Hermjakob, H., Jones, P., & Hubbard, S. J. (2007). Pride Wizard: generation of standards compliant quantitative proteomics data. BMC Systems Biology, 1(S1). doi:10.1186/1752-0509-1-s1-p27
Growth control of the eukaryote cell: a systems biology study in yeast.
Castrillo, J. I., Zeef, L. A., Hoyle, D. C., Zhang, N., Hayes, A., Gardner, D. C., . . . Oliver, S. G. (2007). Growth control of the eukaryote cell: a systems biology study in yeast.. Journal of biology, 6(2), 4. doi:10.1186/jbiol54
An informatic pipeline for the data capture and submission of quantitative proteomic data using iTRAQ™
Siepen, J. A., Swainston, N., Jones, A. R., Hart, S. R., Hermjakob, H., Jones, P., & Hubbard, S. J. (2007). An informatic pipeline for the data capture and submission of quantitative proteomic data using iTRAQ™. PROTEOME SCIENCE, 5. doi:10.1186/1477-5956-5-4
Evidence for multiple circulating factors in preeclampsia
Myers, J. E., Hart, S., Armstrong, S., Mires, G. J., Beynon, R., Gaskell, S. J., & Baker, P. N. (2007). Evidence for multiple circulating factors in preeclampsia. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 196(3), 266-268. doi:10.1016/j.ajog.2006.10.875
2006
Flagellar motility is required for the viability of the bloodstream trypanosome
Broadhead, R., Dawe, H. R., Farr, H., Griffiths, S., Hart, S. R., Portman, N., . . . Gull, K. (2006). Flagellar motility is required for the viability of the bloodstream trypanosome. NATURE, 440(7081), 224-227. doi:10.1038/nature04541
2005
Enhanced phosphopeptide isolation by Fe(III)-IMAC using 1,1,1,3,3,3-hexafluoroisopropanol
Barnouin, K. N., Hart, S. R., Thompson, A. J., Okuyama, M., Waterfield, M., & Cramer, R. (2005). Enhanced phosphopeptide isolation by Fe(III)-IMAC using 1,1,1,3,3,3-hexafluoroisopropanol. PROTEOMICS, 5(17), 4376-4388. doi:10.1002/pmic.200401323
LC-tandem MS in proteome characterization
Hart, S. R., & Gaskell, S. J. (2005). LC-tandem MS in proteome characterization. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 24(7), 566-575. doi:10.1016/j.trac.2005.04.009
2004
PEDRo: A database for storing, searching and disseminating experimental proteomics data - art. no. 68
Garwood, K., McLaughlin, T., Garwood, C., Joens, S., Morrison, N., Taylor, C. F., . . . Paton, N. W. (2004). PEDRo: A database for storing, searching and disseminating experimental proteomics data - art. no. 68. BMC GENOMICS, 5. doi:10.1186/1471-2164-5-68
The analysis of tandem mass spectrometric clatasets: high-throughput investigations require high-quality validation
Hart, S. R., & Riba-Garcia, I. (2004). The analysis of tandem mass spectrometric clatasets: high-throughput investigations require high-quality validation. DRUG DISCOVERY TODAY, 9(9), 391-392. doi:10.1016/S1359-6446(04)03030-2
2003
Characterization of protein phosphorylation by mass spectrometry using immobilized metal ion affinity chromatography with on-resin β-elimination and Michael addition
Thompson, A. J., Hart, S. R., Franz, C., Barnouin, K., Ridley, A., & Cramer, R. (2003). Characterization of protein phosphorylation by mass spectrometry using immobilized metal ion affinity chromatography with on-resin β-elimination and Michael addition. ANALYTICAL CHEMISTRY, 75(13), 3232-3243. doi:10.1021/ac034134h
2002
Immobilized metal ion affinity chromatography for the enrichment of phosphorylated peptides: Application to the identification of phosphorylation sites in signal transduction proteins
Hart, S. R., Foukas, L. C., Shepherd, P. R., & Cramer, R. (2002). Immobilized metal ion affinity chromatography for the enrichment of phosphorylated peptides: Application to the identification of phosphorylation sites in signal transduction proteins. In Proceedings 50th Asms Conference on Mass Spectrometry and Allied Topics (pp. 297-298).
Improving phosphopeptide isolation and mass spectrometric detection by IMAC with on-resin β-elimination and Michael addition
Thompson, A. J., Hart, S., Barnouin, K., & Cramer, R. (2002). Improving phosphopeptide isolation and mass spectrometric detection by IMAC with on-resin β-elimination and Michael addition. In Proceedings 50th Asms Conference on Mass Spectrometry and Allied Topics (pp. 311-312).
Factors governing the solubilization of phosphopeptides retained on ferric NTA IMAC beads and their analysis by MALDI TOFMS
Hart, S. R., Waterfield, M. D., Burlingame, A. L., & Cramer, R. (2002). Factors governing the solubilization of phosphopeptides retained on ferric NTA IMAC beads and their analysis by MALDI TOFMS. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 13(9), 1042-1051. doi:10.1016/S1044-0305(02)00432-4
2000
Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells
Bruce, L. J., Wrong, O., Toye, A. M., Young, M. T., Ogle, G., Ismail, Z., . . . Tanner, M. J. A. (2000). Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells. BIOCHEMICAL JOURNAL, 350, 41-51. doi:10.1042/0264-6021:3500041
Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells
BRUCE, L. J., WRONG, O., TOYE, A. M., YOUNG, M. T., OGLE, G., ISMAIL, Z., . . . TANNER, M. J. A. (2000). Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells. Biochemical Journal, 350(1), 41. doi:10.1042/0264-6021:3500041