Research outputs
2026
MicroAge mission: experimental design and hardware for a bespoke culture system supporting tissue-engineered skeletal muscle.
Jones, S. W., Shigdar, S., Temple, J., Tollitt, B., Janvier, A., Mutter, F., . . . Jackson, M. J. (2026). MicroAge mission: experimental design and hardware for a bespoke culture system supporting tissue-engineered skeletal muscle.. NPJ microgravity. doi:10.1038/s41526-026-00579-z
2025
A comparison of human skeletal muscle cell maturation in 2D versus 3D culture: A quantitative proteomic study
Tollitt, B. R., Jones, S. W., Ohana, J., Henstock, J. R., Jackson, M. J., & Mcardle, A. (2025). A comparison of human skeletal muscle cell maturation in 2D versus 3D culture: A quantitative proteomic study. PHYSIOLOGICAL REPORTS, 13(12). doi:10.14814/phy2.70420
Peroxiredoxin 2 mediates redox-stimulated adaptations to oxidative phosphorylation induced by contractile activity in human skeletal muscle myotubes
Heaton, R. A., Ball, S. T. M., Staunton, C. A., Mouly, V., Jones, S. W., Mcardle, A., & Jackson, M. J. (2025). Peroxiredoxin 2 mediates redox-stimulated adaptations to oxidative phosphorylation induced by contractile activity in human skeletal muscle myotubes. FREE RADICAL BIOLOGY AND MEDICINE, 227, 395-406. doi:10.1016/j.freeradbiomed.2024.11.053
2024
2023
MicroAge Mission: Examining the Effects of Microgravity and Electrical Stimulation on the Proteome of Human Tissue-Engineered Muscle Constructs
Jones, S., Shigdar, S., Hemmings, K., Hoettges, K., Henstock, J., McArdle, C., . . . McArdle, A. (2023). MicroAge Mission: Examining the Effects of Microgravity and Electrical Stimulation on the Proteome of Human Tissue-Engineered Muscle Constructs. FREE RADICAL BIOLOGY AND MEDICINE, 208, S55. doi:10.1016/j.freeradbiomed.2023.10.125
Bioengineering approaches to promote maturity in human skeletal muscle constructs
Tollitt, B., Jones, S., Henstock, J., McArdle, C., Hoettges, K., Jackson, M., & McArdle, A. (2023). Bioengineering approaches to promote maturity in human skeletal muscle constructs. PHYSIOLOGY, 38. doi:10.1152/physiol.2023.38.S1.5732604
Bioengineering approaches to promote maturity in human skeletal muscle constructs
Tollitt, B. R., Jones, S. W., Hoettges, K. F., Henstock, J. R., Neri, G., Jackson, M. J., & McArdle, A. (2023). Bioengineering approaches to promote maturity in human skeletal muscle constructs. In BIOPHYSICAL JOURNAL Vol. 122 (pp. 433A-434A). Retrieved from https://www.webofscience.com/
Bioengineering Approaches To Promote Maturity In Human Skeletal Muscle Constructs
Tollitt, B. R., Jones, S. W., Hoettges, K. F., Henstock, J. R., Jackson, M. J., & McArdle, A. (2023). Bioengineering Approaches To Promote Maturity In Human Skeletal Muscle Constructs. In TISSUE ENGINEERING PART A Vol. 29. Retrieved from https://www.webofscience.com/
2022
Aquaporins: regulators of H2O2 transport and homeostasis in skeletal muscle
Staunton, C. A., Jones, S., McArdle, A., Jackson, M., & Barrett-Jolley, R. (2022). Aquaporins: regulators of H2O2 transport and homeostasis in skeletal muscle. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 192. doi:10.1016/j.freeradbiomed.2022.10.024
MicroAge Mission: Human Muscle Constructs for Studies of Redox-Related Cytokine and Chemokine Release in Microgravity
Jones, S., Shigdar, S., Hemmings, K., Hoettges, K., Henstock, J., McArdle, C., . . . McArdle, A. (2022). MicroAge Mission: Human Muscle Constructs for Studies of Redox-Related Cytokine and Chemokine Release in Microgravity. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 192. doi:10.1016/j.freeradbiomed.2022.10.016
Redox Control of Signalling Responses to Contractile Activity and Ageing in Skeletal Muscle
Jackson, M. J., Pollock, N., Staunton, C., Jones, S., & McArdle, A. (2022). Redox Control of Signalling Responses to Contractile Activity and Ageing in Skeletal Muscle. CELLS, 11(10). doi:10.3390/cells11101698
Cytokine and Chemokine Release from Immortalised Human Myotubes in Culture: Effect of Contractions and Comparison with Isolated Intact Mature Adult Murine Muscle Fibres
Neiland, H. J., Staunton, C. A., Owen, E., Kumiscia, J., Shigdar, S., Jones, S. W., . . . McArdle, A. (2022). Cytokine and Chemokine Release from Immortalised Human Myotubes in Culture: Effect of Contractions and Comparison with Isolated Intact Mature Adult Murine Muscle Fibres. FASEB JOURNAL, 36. doi:10.1096/fasehj.2022.36.S1.L7908
2021
The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review
Jones, S. W., Ball, A. L., Chadwick, A. E., & Alfirevic, A. (2021). The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review. Frontiers in Genetics, 12. doi:10.3389/fgene.2021.698825
Investigating dihydroorotate dehydrogenase inhibitor mediated mitochondrial dysfunction in hepatic in vitro models
Jones, S. W., Penman, S. L., French, N. S., Park, B. K., & Chadwick, A. E. (2021). Investigating dihydroorotate dehydrogenase inhibitor mediated mitochondrial dysfunction in hepatic in vitro models. Toxicology in Vitro, 105096. doi:10.1016/j.tiv.2021.105096
2020
Development of Functional, Contractile 3-D Human Muscle Constructs for Studies of the Effects of Microgravity on Muscle Mass and Function
Jones, S., Janvier, A., Shigdar, S., Henstock, J., McArdle, C., Hoettges, K., . . . Jackson, M. (2020). Development of Functional, Contractile 3-D Human Muscle Constructs for Studies of the Effects of Microgravity on Muscle Mass and Function. In FASEB JOURNAL Vol. 34. doi:10.1096/fasebj.2020.34.s1.06751
2019
Investigating mitochondrial impairment as a mechanism of statin-induced muscle toxicity
Jones, S. W. (2019). Investigating mitochondrial impairment as a mechanism of statin-induced muscle toxicity.
Microage: Microgravity as a model for accelerated skeletal muscle ageing
Jones, S., McArdle, A., Henstock, J., Hoettges, K., Janvier, A., McArdle, C., . . . Jackson, M. J. (2019). Microage: Microgravity as a model for accelerated skeletal muscle ageing. In Proceedings of the International Astronautical Congress Iac Vol. 2019-October.