Research outputs
Selected research outputs
- Challenges for global antibiotic regimen planning and establishing antimicrobial resistance targets: implications for the WHO Essential Medicines List and AWaRe antibiotic book dosing (Journal article - 2024)
2025
Antimicrobial use and resistance
Reza, N., Dubey, V., Sharland, M., & Hope, W. (2025). Antimicrobial use and resistance. BMJ-BRITISH MEDICAL JOURNAL, 391. doi:10.1136/bmj-2024-082681
Drug-resistant <i>Acinetobacter baumannii</i>: mortality, emerging treatments, and future pharmacological targets for a WHO priority pathogen
Dubey, V., Reza, N., & Hope, W. (2025). Drug-resistant <i>Acinetobacter baumannii</i>: mortality, emerging treatments, and future pharmacological targets for a WHO priority pathogen. CLINICAL MICROBIOLOGY REVIEWS, 38(3). doi:10.1128/cmr.00279-24
Combining antibiotics to tackle antimicrobial resistance (vol 10, pg 813, 2025)
Hope, W., Nambiar, S., O'Brien, S., Sharland, M., Paterson, D. L., Yin, M., . . . Howard, A. (2025). Combining antibiotics to tackle antimicrobial resistance (vol 10, pg 813, 2025). NATURE MICROBIOLOGY, 10(5), 1258. doi:10.1038/s41564-025-02003-w
Combining antibiotics to tackle antimicrobial resistance
Hope, W., Nambiar, S., O'Brien, S., Sharland, M., Paterson, D. L., Yin, M., . . . Howard, A. (2025). Combining antibiotics to tackle antimicrobial resistance. NATURE MICROBIOLOGY, 10(4), 813-816. doi:10.1038/s41564-025-01969-x
2024
Simulation to optimize the laboratory diagnosis of bacteremia
Gerada, A., Roberts, G., Howard, A., Reza, N., Velluva, A., Rosato, C., . . . Hope, W. (2024). Simulation to optimize the laboratory diagnosis of bacteremia. MICROBIOLOGY SPECTRUM, 12(11). doi:10.1128/spectrum.01449-24
<i>Strongyloides</i><i> stercoralis</i> infection in the UK: A systematic review and meta-analysis of published cases
Alam, A. M., Ozdemir, C., & Reza, N. (2024). <i>Strongyloides</i><i> stercoralis</i> infection in the UK: A systematic review and meta-analysis of published cases. CLINICAL MEDICINE, 24(4). doi:10.1016/j.clinme.2024.100227
Challenges for global antibiotic regimen planning and establishing antimicrobial resistance targets: implications for the WHO Essential Medicines List and AWaRe antibiotic book dosing
Reza, N., Gerada, A., Stott, K. E., Howard, A., Sharland, M., & Hope, W. (2024). Challenges for global antibiotic regimen planning and establishing antimicrobial resistance targets: implications for the WHO Essential Medicines List and AWaRe antibiotic book dosing. CLINICAL MICROBIOLOGY REVIEWS, 37(2). doi:10.1128/cmr.00139-23
Determination of minimum inhibitory concentrations using machine-learning-assisted agar dilution.
Gerada, A., Harper, N., Howard, A., Reza, N., & Hope, W. (2024). Determination of minimum inhibitory concentrations using machine-learning-assisted agar dilution.. Microbiology spectrum, e0420923. doi:10.1128/spectrum.04209-23
Antimicrobial learning systems: an implementation blueprint for artificial intelligence to tackle antimicrobial resistance
Howard, A., Aston, S., Gerada, A., Reza, N., Bincalar, J., Mwandumba, H., . . . Buchan, I. (2024). Antimicrobial learning systems: an implementation blueprint for artificial intelligence to tackle antimicrobial resistance. LANCET DIGITAL HEALTH, 6(1). doi:10.1016/S2589-7500(23)00221-2
Antimicrobial treatment imprecision: an outcome-based model to close the data-to-action loop
Howard, A., Reza, N., Aston, S., Woods, B., Gerada, A., Buchan, I., . . . Maertson, A. -G. (2024). Antimicrobial treatment imprecision: an outcome-based model to close the data-to-action loop. LANCET INFECTIOUS DISEASES, 24(1), e47-e58. doi:10.1016/S1473-3099(23)00367-5
2022
Validation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery
Ahmed, W. U. R., Bhatia, S., McLean, K. A., Khaw, R., Baker, D., Kamarajah, S. K., . . . Eftychiou, S. (2022). Validation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery. BJS OPEN, 6(1). doi:10.1093/bjsopen/zrab150
2021
Impact of postoperative acute kidney injury in patients undergoing major gastrointestinal surgery on 1-year survival and renal outcomes: a national multicentre cohort study.
STARSurg Collaborative. (2021). Impact of postoperative acute kidney injury in patients undergoing major gastrointestinal surgery on 1-year survival and renal outcomes: a national multicentre cohort study.. BJS open, 5(6), zrab134. doi:10.1093/bjsopen/zrab134
Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease
Tan, L. K. K., Reglinski, M., Teo, D., Reza, N., Lamb, L. E. M., Nageshwaran, V., . . . Sriskandan, S. (2021). Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease. NPJ VACCINES, 6(1). doi:10.1038/s41541-021-00326-3
2020
Perioperative intravenous contrast administration and the incidence of acute kidney injury after major gastrointestinal surgery: prospective, multicentre cohort study
McLean, K. A. (2020). Perioperative intravenous contrast administration and the incidence of acute kidney injury after major gastrointestinal surgery: prospective, multicentre cohort study. BRITISH JOURNAL OF SURGERY, 107(8), 1023-1032. doi:10.1002/bjs.11453
2019
Challenges of one-year longitudinal follow-up of a prospective, observational cohort study using an anonymised database: recommendations for trainee research collaboratives
Challenges of one-year longitudinal follow-up of a prospective, observational cohort study using an anonymised database: recommendations for trainee research collaboratives (2019). BMC MEDICAL RESEARCH METHODOLOGY, 19(1). doi:10.1186/s12874-019-0857-y
2018
Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study
Nepogodiev, D., Walker, K., Glasbey, J. C., Drake, T. M., Borakati, A., Kamarajah, S., . . . Underhill, R. (2018). Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study. BJS OPEN, 2(6), 400-410. doi:10.1002/bjs5.86
Association between peri-operative angiotensin-converting enzyme inhibitors and angiotensin-2 receptor blockers and acute kidney injury in major elective non-cardiac surgery: a multicentre, prospective cohort study
Drake, T. M. (2018). Association between peri-operative angiotensin-converting enzyme inhibitors and angiotensin-2 receptor blockers and acute kidney injury in major elective non-cardiac surgery: a multicentre, prospective cohort study. ANAESTHESIA, 73(10), 1214-1222. doi:10.1111/anae.14349