Research outputs
2026
Hypervirulent serotype 1 pneumococci display high levels of nasal shedding and rapid onward transmission
Baltazar, M., Jacques, L. C., Audshasai, T., O'brien, M., & Kadioglu, A. (2026). Hypervirulent serotype 1 pneumococci display high levels of nasal shedding and rapid onward transmission. JOURNAL OF INFECTION, 92(1). doi:10.1016/j.jinf.2025.106665
2025
Nasal delivery of killed Bacillus subtilis spores protects against influenza, RSV and SARS-CoV-2
Xu, R., Hong, H. A., Khandaker, S., Baltazar, M., Allehyani, N., Beentjes, D., . . . Kadioglu, A. (2025). Nasal delivery of killed Bacillus subtilis spores protects against influenza, RSV and SARS-CoV-2. Frontiers in Immunology, 16. doi:10.3389/fimmu.2025.1501907
2024
The <i>Streptococcus agalactiae</i> LytSR two-component regulatory system promotes vaginal colonization and virulence <i>in vivo</i>
Alqadeeb, H., Baltazar, M., Cazares, A., Poonpanichakul, T., Kjos, M., French, N., . . . O'Brien, M. (2024). The <i>Streptococcus agalactiae</i> LytSR two-component regulatory system promotes vaginal colonization and virulence <i>in vivo</i>. MICROBIOLOGY SPECTRUM, 12(11). doi:10.1128/spectrum.01970-24
The<i>Streptococcus agalactiae</i>LytSR two-component regulatory system promotes vaginal colonisation and virulence<i>in vivo</i>
Design of a millifluidic device for the evaluation of blue-light disinfection on Pseudomonas aeruginosa PA01 biofilm
Maldonado-Carmona, N., Baltazar, M., Fothergill, J. L., & Henry, N. (2024). Design of a millifluidic device for the evaluation of blue-light disinfection on Pseudomonas aeruginosa PA01 biofilm. Photodiagnosis and Photodynamic Therapy, 46, 104161. doi:10.1016/j.pdpdt.2024.104161
2023
Quantifying neutralising antibody responses against SARS-CoV-2 in dried blood spots (DBS) and paired sera
Roper, K. J., Thomas, J., Albalawi, W., Maddocks, E., Dobson, S., Alshehri, A., . . . Pollakis, G. (2023). Quantifying neutralising antibody responses against SARS-CoV-2 in dried blood spots (DBS) and paired sera. SCIENTIFIC REPORTS, 13(1). doi:10.1038/s41598-023-41928-2
Hypervirulent pneumococci display high levels of nasopharyngeal shedding and rapid onward transmission
Influence of Streptococcus pneumoniae Within-Strain Population Diversity on Virulence and Pathogenesis
Jacques, L. C., Green, A. E., Barton, T. E., Baltazar, M., Aleksandrowicz, J., Xu, R., . . . Neill, D. R. (2023). Influence of Streptococcus pneumoniae Within-Strain Population Diversity on Virulence and Pathogenesis. MICROBIOLOGY SPECTRUM, 11(1). doi:10.1128/spectrum.03103-22
2022
Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity (vol 10, 17313, 2020)
Panagiotou, S., Chaguza, C., Yahya, R., Audshasai, T., Baltazar, M., Ressel, L., . . . Yang, M. (2022). Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity (vol 10, 17313, 2020). SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-08813-w
Streptococcus pneumoniae Rapidly Translocate from the Nasopharynx through the Cribriform Plate to Invade the Outer Meninges
Audshasai, T., Coles, J. A., Panagiotou, S., Khandaker, S., Scales, H. E., Kjos, M., . . . Yang, M. (2022). Streptococcus pneumoniae Rapidly Translocate from the Nasopharynx through the Cribriform Plate to Invade the Outer Meninges. MBIO, 13(4). doi:10.1128/mbio.01024-22
Activation of class 1 integron integrase is promoted in the intestinal environment
Baltazar, M., Bourgeois-Nicolaos, N., Larroude, M., Couet, W., Uwajeneza, S., Doucet-Populaire, F., . . . Da Re, S. (2022). Activation of class 1 integron integrase is promoted in the intestinal environment. PLOS GENETICS, 18(4). doi:10.1371/journal.pgen.1010177
2021
Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity (vol 10, 17313, 2020)
Panagiotou, S., Chaguza, C., Yahya, R., Audshasai, T., Baltazar, M., Ressel, L., . . . Yang, M. (2021). Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity (vol 10, 17313, 2020). SCIENTIFIC REPORTS, 11(1). doi:10.1038/s41598-021-86214-1
Streptolysin O concentration and activity is central to in vivo phenotype and disease outcome in Group A Streptococcus infection
Clarke, J., Baltazar, M., Alsahag, M., Panagiotou, S., Pouget, M., Paxton, W. A., . . . Kadioglu, A. (2021). Streptolysin O concentration and activity is central to in vivo phenotype and disease outcome in Group A Streptococcus infection. SCIENTIFIC REPORTS, 11(1). doi:10.1038/s41598-021-97866-4
<i>Streptococcus pneumoniae</i> rapidly translocates from the nasopharynx through the cribriform plate to invade and inflame the dura
2020
Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity
Panagiotou, S., Chaguza, C., Yahya, R., Audshasai, T., Baltazar, M., Ressel, L., . . . Yang, M. (2020). Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity. SCIENTIFIC REPORTS, 10(1). doi:10.1038/s41598-020-73454-w
Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin
Jacques, L. C., Panagiotou, S., Baltazar, M., Senghore, M., Khandaker, S., Xu, R., . . . Kadioglu, A. (2020). Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin. NATURE COMMUNICATIONS, 11(1). doi:10.1038/s41467-020-15751-6
2019
Streptolysin production and activity is central to<i>in vivo</i>pathotype and disease outcome in GAS infections
Clarke, J., Baltazar, M., Alsahag, M., Panagiotou, S., Pouget, M., Paxton, W., . . . Kadioglu, A. (2019). Streptolysin production and activity is central to<i>in vivo</i>pathotype and disease outcome in GAS infections. doi:10.1101/686303
2015
Multidrug-Resistant <i>Salmonella enterica</i>, Serotype Typhi, Gulf of Guinea Region, Africa
Baltazar, M., Ngandjio, A., Holt, K. E., Lepillet, E., Pardos de la Gandara, M., Collard, J. -M., . . . Weill, F. -X. (2015). Multidrug-Resistant <i>Salmonella enterica</i>, Serotype Typhi, Gulf of Guinea Region, Africa. EMERGING INFECTIOUS DISEASES, 21(4), 655-659. doi:10.3201/eid2104.141355
Undated
Inhaled Delivery of Killed Bacillus Subtilis Spores Protects Against Acute Viral Infections Caused by Influenza, RSV and SARS-CoV-2
Xu, R., Hong, H. A., Shadia, K., Baltazar, M., Allehyani, N., Beentjes, D., . . . Kadioglu, A. (n.d.). Inhaled Delivery of Killed Bacillus Subtilis Spores Protects Against Acute Viral Infections Caused by Influenza, RSV and SARS-CoV-2.