Research outputs
2026
A systematic guide for identifying transcription factors that directly regulate the expression of a gene of interest.
Bates, A. D., Grzela, D., Studzian, M., Brennan, L., Williams, M., Fawcett, C., . . . McClurg, U. L. (2026). A systematic guide for identifying transcription factors that directly regulate the expression of a gene of interest.. Genome research. doi:10.1101/gr.281154.125
2025
Structural and epistatic regulatory variants cause hallmark white spotting in cattle
Jivanji, S., Wilkinson, E., Tang, L., Tiplady, K. M., Yeates, A., Harland, C., . . . Littlejohn, M. D. (2025). Structural and epistatic regulatory variants cause hallmark white spotting in cattle. SCIENCE ADVANCES, 11(46). doi:10.1126/sciadv.adt5913
Moonlighting Role of Meiotic SYCP1 in Breast Cancer: A Chromatin-Bound Regulator of DNA Repair, Transcription, and Drug Resistance
2023
Genetically engineered multicistronic allele of <i>Pmel</i> yielding highly specific CreERT2-mediated recombination in the melanocyte lineage
Wilkinson, E. L., Brennan, L. C., Harrison, O. J., Crane-Smith, Z., Gautier, P., Keighren, M. A., . . . Mort, R. L. (2023). Genetically engineered multicistronic allele of <i>Pmel</i> yielding highly specific CreERT2-mediated recombination in the melanocyte lineage. PIGMENT CELL & MELANOMA RESEARCH, 36(1), 71-77. doi:10.1111/pcmr.13076
2021
Cystatin M/E Variant Causes Autosomal Dominant Keratosis Follicularis Spinulosa Decalvans by Dysregulating Cathepsins L and V
Eckl, K. M., Gruber, R., Brennan, L., Marriott, A., Plank, R., Moosbrugger-Martinz, V., . . . Schmuth, M. (2021). Cystatin M/E Variant Causes Autosomal Dominant Keratosis Follicularis Spinulosa Decalvans by Dysregulating Cathepsins L and V. FRONTIERS IN GENETICS, 12. doi:10.3389/fgene.2021.689940