Research outputs
2025
Monkeypox virus-neutralising antibodies detected against Clade Ib and Clade IIb in healthy individuals following MVA-BN vaccination
2023
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses
Michael, B. D., Dunai, C., Needham, E. J., Tharmaratnam, K., Williams, R., Huang, Y., . . . Menon, D. K. (2023). Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses. Nature Communications, 14(1). doi:10.1038/s41467-023-42320-4
Modified vaccinia Ankara–Bavarian Nordic vaccine against mpox in children
Turtle, L., & Subramaniam, K. (2023). Modified vaccinia Ankara–Bavarian Nordic vaccine against mpox in children. The Lancet Infectious Diseases, 23(9), 989-990. doi:10.1016/s1473-3099(23)00345-6
Impact of peptide:HLA complex stability for the identification of SARS-CoV-2-specific CD8+T cells
Lie-Andersen, O., Hübbe, M. L., Subramaniam, K., Steen-Jensen, D., Bergmann, A. C., Justesen, D., . . . Hansen, M. (2023). Impact of peptide:HLA complex stability for the identification of SARS-CoV-2-specific CD8+T cells. Frontiers in Immunology, 14. doi:10.3389/fimmu.2023.1151659
2022
Neuroinvasion and Neurotropism by SARS-CoV-2 Variants in the K18-hACE2 Mouse
Seehusen, F., Clark, J. J., Sharma, P., Bentley, E. G., Kirby, A., Subramaniam, K., . . . Kipar, A. (2022). Neuroinvasion and Neurotropism by SARS-CoV-2 Variants in the K18-hACE2 Mouse. Viruses, 14(5), 1020. doi:10.3390/v14051020
Mouse models of Japanese encephalitis virus infection: A systematic review and meta-analysis using a meta-regression approach
Bharucha, T., Cleary, B., Farmiloe, A., Sutton, E., Hayati, H., Kirkwood, P., . . . Turtle, L. (2022). Mouse models of Japanese encephalitis virus infection: A systematic review and meta-analysis using a meta-regression approach. PLOS Neglected Tropical Diseases, 16(2), e0010116. doi:10.1371/journal.pntd.0010116
2021
Investigation of SARS-CoV-2 faecal shedding in the community: a prospective household cohort study (COVID-LIV) in the UK
Vaselli, N. M., Setiabudi, W., Subramaniam, K., Adams, E. R., Turtle, L., Iturriza-Gómara, M., . . . Gkioni, E. (2021). Investigation of SARS-CoV-2 faecal shedding in the community: a prospective household cohort study (COVID-LIV) in the UK. BMC Infectious Diseases, 21(1). doi:10.1186/s12879-021-06443-7
Detection of Serum Cross-Reactive Antibodies and Memory Response to SARS-CoV-2 in Prepandemic and Post–COVID-19 Convalescent Samples
Shrwani, K., Sharma, R., Krishnan, M., Jones, T., Mayora-Neto, M., Cantoni, D., . . . Zhang, Q. (2021). Detection of Serum Cross-Reactive Antibodies and Memory Response to SARS-CoV-2 in Prepandemic and Post–COVID-19 Convalescent Samples. The Journal of Infectious Diseases, 224(8), 1305-1315. doi:10.1093/infdis/jiab333
Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study
Drake, T. M., Riad, A. M., Fairfield, C. J., Egan, C., Knight, S. R., Pius, R., . . . Young, P. (2021). Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study. The Lancet, 398(10296), 223-237. doi:10.1016/s0140-6736(21)00799-6
Prospective observational study of SARS-CoV-2 infection, transmission and immunity in a cohort of households in Liverpool City Region, UK (COVID-LIV): a study protocol
Setiabudi, W., Hungerford, D., Subramaniam, K., Vaselli, N. M., Shaw, V. E., Wilton, M., . . . French, N. (2021). Prospective observational study of SARS-CoV-2 infection, transmission and immunity in a cohort of households in Liverpool City Region, UK (COVID-LIV): a study protocol. BMJ Open, 11(3), e048317. doi:10.1136/bmjopen-2020-048317
2020
Broad and strong memory CD4(+)and CD8(+)T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
Peng, Y., Mentzer, A. J., Liu, G., Yao, X., Yin, Z., Dong, D., . . . Investigators, I. (2020). Broad and strong memory CD4(+)and CD8(+)T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19. NATURE IMMUNOLOGY, 21(11), 1336-1345. doi:10.1038/s41590-020-0782-6
Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease: An International Multicenter Study.
Drake, T. M., Docherty, A. B., Harrison, E. M., Quint, J. K., Adamali, H., Agnew, S., . . . ISARIC4C Investigators. (2020). Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease: An International Multicenter Study.. Am J Respir Crit Care Med. doi:10.1164/rccm.202007-2794OC
Two Is Better Than One: Evidence for T-Cell Cross-Protection Between Dengue and Zika and Implications on Vaccine Design.
Subramaniam, K. S., Lant, S., Goodwin, L., Grifoni, A., Weiskopf, D., & Turtle, L. (2020). Two Is Better Than One: Evidence for T-Cell Cross-Protection Between Dengue and Zika and Implications on Vaccine Design.. Frontiers in Immunology, 11, 517. doi:10.3389/fimmu.2020.00517
2019
Synthesis of neoglycoproteins as potential diagnostic tools for cutaneous leishmaniasis
Montoya, A., Subramaniam, K., Austin, V., Acosta-Serrano, A., & Michael, K. (2019). Synthesis of neoglycoproteins as potential diagnostic tools for cutaneous leishmaniasis. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 257. Retrieved from https://www.webofscience.com/
2018
Anti-α-Gal antibodies detected by novel neoglycoproteins as a diagnostic tool for Old World cutaneous leishmaniasis caused by<i>Leishmania major</i>
Subramaniam, K. S., Austin, V., Schocker, N. S., Montoya, A. L., Anderson, M. S., Ashmus, R. A., . . . Acosta-Serrano, A. (2018). Anti-α-Gal antibodies detected by novel neoglycoproteins as a diagnostic tool for Old World cutaneous leishmaniasis caused by<i>Leishmania major</i>. Parasitology, 145(13), 1758-1764. doi:10.1017/s0031182018000860
Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: trends in pyrethroid resistance during a WHO-coordinated multi-country prospective study
Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: trends in pyrethroid resistance during a WHO-coordinated multi-country prospective study (2018). Parasites & Vectors, 11(1). doi:10.1186/s13071-018-3101-4
Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: a WHO-coordinated, prospective, international, observational cohort study
Kleinschmidt, I., Bradley, J., Knox, T. B., Mnzava, A. P., Kafy, H. T., Mbogo, C., . . . Donnelly, M. J. (2018). Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: a WHO-coordinated, prospective, international, observational cohort study. LANCET INFECTIOUS DISEASES, 18(6), 640-649. doi:10.1016/S1473-3099(18)30172-5
Temporal and spatial trends in insecticide resistance in Anopheles arabiensis in Sudan: outcomes from an evaluation of implications of insecticide resistance for malaria vector control
Ismail, B. A., Kafy, H. T., Sulieman, J. E., Subramaniam, K., Thomas, B., Mnzava, A., . . . Donnelly, M. J. (2018). Temporal and spatial trends in insecticide resistance in Anopheles arabiensis in Sudan: outcomes from an evaluation of implications of insecticide resistance for malaria vector control. Parasites & Vectors, 11(1). doi:10.1186/s13071-018-2732-9
A high parasite density environment induces transcriptional changes and cell death in <i>Plasmodium falciparum</i> blood stages
Chou, E. S., Abidi, S. Z., Teye, M., Leliwa‐Sytek, A., Rask, T. S., Cobbold, S. A., . . . Day, K. P. (2018). A high parasite density environment induces transcriptional changes and cell death in <i>Plasmodium falciparum</i> blood stages. The FEBS Journal, 285(5), 848-870. doi:10.1111/febs.14370
SURFACE GLYCOCONJUGATES FROM <it>LEISHMANIA MAJOR</it> AND <it>L-TROPICA</it> AS TARGETS FOR HUMAN HOST IMMUNE RESPONSE
Austin, V., Subramaniam, K., Montoya, A., Schocker, N., Michaels, K., Almeida, I., & Serrano, A. (2018). SURFACE GLYCOCONJUGATES FROM <it>LEISHMANIA MAJOR</it> AND <it>L-TROPICA</it> AS TARGETS FOR HUMAN HOST IMMUNE RESPONSE. In AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Vol. 99 (pp. 403-404). Retrieved from https://www.webofscience.com/
2017
Impact of insecticide resistance in Anopheles arabiensis on malaria incidence and prevalence in Sudan and the costs of mitigation
Kafy, H. T., Ismail, B. A., Mnzava, A. P., Lines, J., Abdin, M. S. E., Eltaher, J. S., . . . Kleinschmidt, I. (2017). Impact of insecticide resistance in <i>Anopheles arabiensis</i> on malaria incidence and prevalence in Sudan and the costs of mitigation. Proceedings of the National Academy of Sciences, 114(52). doi:10.1073/pnas.1713814114
An α-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major
Iniguez, E., Schocker, N. S., Subramaniam, K., Portillo, S., Montoya, A. L., Al-Salem, W. S., . . . Maldonado, R. A. (2017). An α-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major. PLOS Neglected Tropical Diseases, 11(10), e0006039. doi:10.1371/journal.pntd.0006039
Detection and quantitation of copy number variation in the voltage-gated sodium channel gene of the mosquito Culex quinquefasciatus
Martins, W. F. S., Subramaniam, K., Steen, K., Mawejje, H., Liloglou, T., Donnelly, M. J., & Wilding, C. S. (2017). Detection and quantitation of copy number variation in the voltage-gated sodium channel gene of the mosquito Culex quinquefasciatus. Scientific Reports, 7(1). doi:10.1038/s41598-017-06080-8
Insecticide-Treated Nets and Protection against Insecticide-Resistant Malaria Vectors in Western Kenya
Ochomo, E., Chahilu, M., Cook, J., Kinyari, T., Bayoh, N. M., West, P., . . . Mbogo, C. (2017). Insecticide-Treated Nets and Protection against Insecticide-Resistant Malaria Vectors in Western Kenya. Emerging Infectious Diseases, 23(5), 758-764. doi:10.3201/eid2305.161315
INSECTICIDE-TREATED NETS AND PROTECTION AGAINST INSECTICIDE-RESISTANT MALARIA VECTORS IN WESTERN KENYA
Ochomo, E., Chahilu, M., Cook, J., Kinyari, T., Bayoh, N. M., West, P., . . . Mbogo, C. (2017). INSECTICIDE-TREATED NETS AND PROTECTION AGAINST INSECTICIDE-RESISTANT MALARIA VECTORS IN WESTERN KENYA. In AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Vol. 97 (pp. 105). Retrieved from https://www.webofscience.com/
Neoglycoproteins as biomarkers for cutaneous leishmaniasis
Montoya, A. L., Subramaniam, K., Acosta-Serrano, A., Almeida, I. C., & Michael, K. (2017). Neoglycoproteins as biomarkers for cutaneous leishmaniasis. In GLYCOBIOLOGY Vol. 27 (pp. 1181). Retrieved from https://www.webofscience.com/
2016
Cutaneous Leishmaniasis and Conflict in Syria
Al-Salem, W. S., Pigott, D. M., Subramaniam, K., Haines, L. R., Kelly-Hope, L., Molyneux, D. H., . . . Acosta-Serrano, A. (2016). Cutaneous Leishmaniasis and Conflict in Syria. Emerging Infectious Diseases, 22(5), 931-933. doi:10.3201/eid2205.160042
2015
Presence of the knockdown resistance mutation, Vgsc-1014F in Anopheles gambiae and An. arabiensis in western Kenya
Ochomo, E., Subramaniam, K., Kemei, B., Rippon, E., Bayoh, N. M., Kamau, L., . . . Mbogo, C. (2015). Presence of the knockdown resistance mutation, Vgsc-1014F in Anopheles gambiae and An. arabiensis in western Kenya. Parasites & Vectors, 8(1). doi:10.1186/s13071-015-1223-5
Insecticide resistance profile of Anopheles gambiae from a phase II field station in Cové, southern Benin: implications for the evaluation of novel vector control products
Ngufor, C., N’Guessan, R., Fagbohoun, J., Subramaniam, K., Odjo, A., Fongnikin, A., . . . Rowland, M. (2015). Insecticide resistance profile of Anopheles gambiae from a phase II field station in Cové, southern Benin: implications for the evaluation of novel vector control products. Malaria Journal, 14(1). doi:10.1186/s12936-015-0981-z
The T-Cell Inhibitory Molecule Butyrophilin-Like 2 Is Up-regulated in Mild<i>Plasmodium falciparum</i>Infection and Is Protective During Experimental Cerebral Malaria
Subramaniam, K. S., Spaulding, E., Ivan, E., Mutimura, E., Kim, R. S., Liu, X., . . . Daily, J. P. (2015). The T-Cell Inhibitory Molecule Butyrophilin-Like 2 Is Up-regulated in Mild<i>Plasmodium falciparum</i>Infection and Is Protective During Experimental Cerebral Malaria. Journal of Infectious Diseases, 212(8), 1322-1331. doi:10.1093/infdis/jiv217
Design of a study to determine the impact of insecticide resistance on malaria vector control: a multi-country investigation
Kleinschmidt, I., Mnzava, A. P., Kafy, H. T., Mbogo, C., Bashir, A. I., Bigoga, J., . . . Donnelly, M. J. (2015). Design of a study to determine the impact of insecticide resistance on malaria vector control: a multi-country investigation. Malaria Journal, 14(1). doi:10.1186/s12936-015-0782-4
HIV Malaria Co-Infection Is Associated with Atypical Memory B Cell Expansion and a Reduced Antibody Response to a Broad Array of Plasmodium falciparum Antigens in Rwandan Adults
Subramaniam, K. S., Skinner, J., Ivan, E., Mutimura, E., Kim, R. S., Feintuch, C. M., . . . Daily, J. P. (2015). HIV Malaria Co-Infection Is Associated with Atypical Memory B Cell Expansion and a Reduced Antibody Response to a Broad Array of Plasmodium falciparum Antigens in Rwandan Adults. PLOS ONE, 10(4), e0124412. doi:10.1371/journal.pone.0124412
2014
Host Defense Against Cryptococcal Disease: Is There a Role for B Cells and Antibody-Mediated Immunity?
Datta, K., & Subramaniam, K. S. (2014). Host Defense Against Cryptococcal Disease: Is There a Role for B Cells and Antibody-Mediated Immunity?. Current Fungal Infection Reports, 8(4), 287-295. doi:10.1007/s12281-014-0208-8
Plasmodium falciparum Infection Does Not Affect Human Immunodeficiency Virus Viral Load in Coinfected Rwandan Adults
Subramaniam, K., Plank, R. M., Lin, N., Goldman-Yassen, A., Ivan, E., Becerril, C., . . . Daily, J. P. (2014). Plasmodium falciparum Infection Does Not Affect Human Immunodeficiency Virus Viral Load in Coinfected Rwandan Adults. Open Forum Infectious Diseases, 1(2). doi:10.1093/ofid/ofu066
Pyrethroid susceptibility of malaria vectors in four Districts of western Kenya
Ochomo, E., Bayoh, N. M., Kamau, L., Atieli, F., Vulule, J., Ouma, C., . . . Mbogo, C. (2014). Pyrethroid susceptibility of malaria vectors in four Districts of western Kenya. Parasites & Vectors, 7(1), 310. doi:10.1186/1756-3305-7-310
2010
The Absence of Serum IgM Enhances the Susceptibility of Mice to Pulmonary Challenge with <i>Cryptococcus neoformans</i>
Subramaniam, K. S., Datta, K., Quintero, E., Manix, C., Marks, M. S., & Pirofski, L. -A. (2010). The Absence of Serum IgM Enhances the Susceptibility of Mice to Pulmonary Challenge with <i>Cryptococcus neoformans</i>. The Journal of Immunology, 184(10), 5755-5767. doi:10.4049/jimmunol.0901638
INDUCTION OF AN ENVIRONMENTAL STRESS RESPONSE IN <i>PLASMODIUM FALCIPARUM</i> USING HUMAN INNATE IMMUNE CELLS
Subramaniam, K. (2010). INDUCTION OF AN ENVIRONMENTAL STRESS RESPONSE IN <i>PLASMODIUM FALCIPARUM</i> USING HUMAN INNATE IMMUNE CELLS. In AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Vol. 83 (pp. 129). Retrieved from https://www.webofscience.com/
Improved Survival of Mice Deficient in Secretory Immunoglobulin M following Systemic Infection with<i>Cryptococcus neoformans</i>
Subramaniam, K. S., Datta, K., Marks, M. S., & Pirofski, L. -A. (2010). Improved Survival of Mice Deficient in Secretory Immunoglobulin M following Systemic Infection with<i>Cryptococcus neoformans</i>. Infection and Immunity, 78(1), 441-452. doi:10.1128/iai.00506-09
2009
IgM <sup>+</sup> Memory B Cell Expression Predicts HIV‐Associated Cryptococcosis Status
Subramaniam, K., Metzger, B., Hanau, L. H., Guh, A., Rucker, L., Badri, S., & Pirofski, L. (2009). IgM <sup>+</sup> Memory B Cell Expression Predicts HIV‐Associated Cryptococcosis Status. In The Journal of Infectious Diseases Vol. 200 (pp. 244-251). Oxford University Press (OUP). doi:10.1086/599318
2005
<i>Cryptococcus neoformans</i> -Reactive and Total Immunoglobulin Profiles of Human Immunodeficiency Virus-Infected and Uninfected Ugandans
Subramaniam, K., French, N., & Pirofski, L. -A. (2005). <i>Cryptococcus neoformans</i> -Reactive and Total Immunoglobulin Profiles of Human Immunodeficiency Virus-Infected and Uninfected Ugandans. Clinical and Vaccine Immunology, 12(10), 1168-1176. doi:10.1128/cdli.12.10.1168-1176.2005
2004
Protective and Nonprotective Human Immunoglobulin M Monoclonal Antibodies to<i>Cryptococcus neoformans</i>Glucuronoxylomannan Manifest Different Specificities and Gene Use Profiles
Maitta, R. W., Datta, K., Chang, Q., Luo, R. X., Witover, B., Subramaniam, K., & Pirofski, L. -A. (2004). Protective and Nonprotective Human Immunoglobulin M Monoclonal Antibodies to<i>Cryptococcus neoformans</i>Glucuronoxylomannan Manifest Different Specificities and Gene Use Profiles. Infection and Immunity, 72(8), 4810-4818. doi:10.1128/iai.72.8.4810-4818.2004
2003
Qualitative Change in Antibody Responses of Human Immunodeficiency Virus–Infected Individuals to Pneumococcal Capsular Polysaccharide Vaccination Associated with Highly Active Antiretroviral Therapy
Subramaniam, K. S., Segal, R., Lyles, R. H., Rodriguez‐Barradas, M. C., & Pirofski, L. (2003). Qualitative Change in Antibody Responses of Human Immunodeficiency Virus–Infected Individuals to Pneumococcal Capsular Polysaccharide Vaccination Associated with Highly Active Antiretroviral Therapy. The Journal of Infectious Diseases, 187(5), 758-768. doi:10.1086/368331