Research outputs
2026
Process evaluation results of FEMuR III randomised controlled trial (RCT), a community-based rehabilitation following hip fracture surgery
Ralph, P., Dobson, S., Dodd, S., Dorkenoo, S., Doungsong, K. P., Tudor Edwards, R., . . . Williams, N. H. (2026). Process evaluation results of FEMuR III randomised controlled trial (RCT), a community-based rehabilitation following hip fracture surgery. Disability and Rehabilitation, 1-20. doi:10.1080/09638288.2026.2636386
Devaluation insensitivity of event related potentials associated with food cues
Sambrook, T. D., Wills, A. J., Hardwick, B., & Goslin, J. (2026). Devaluation insensitivity of event related potentials associated with food cues. Appetite, 218, 108390. doi:10.1016/j.appet.2025.108390
Safety and efficacy of adjunct dexamethasone in adults with herpes simplex virus encephalitis in the UK (DexEnceph): a multicentre, observer-blind, randomised, phase 3, controlled trial
Solomon, T., Hooper, C., Easton, A., Rosala-Hallas, A., Facer, B., Moore, P., . . . Ellul, M. A. (2026). Safety and efficacy of adjunct dexamethasone in adults with herpes simplex virus encephalitis in the UK (DexEnceph): a multicentre, observer-blind, randomised, phase 3, controlled trial. The Lancet Neurology, 25(2), 136-146. doi:10.1016/s1474-4422(25)00454-5
2025
Bayesian trial of adalimumab versus secukinumab for children with juvenile idiopathic arthritis associated uveitis or chronic anterior uveitis
Ramanan, A. V., Dick, A. D., Jaki, T., Caruso, G., Robertson, D. S., Jones, A. P., . . . Beresford, M. W. (2025). Bayesian trial of adalimumab versus secukinumab for children with juvenile idiopathic arthritis associated uveitis or chronic anterior uveitis. Pediatric Rheumatology, 23(1). doi:10.1186/s12969-025-01107-1
Effectiveness of a community-based rehabilitation programme following hip fracture: results from the Fracture in the Elderly Multidisciplinary Rehabilitation phase III (FEMuR III) randomised controlled trial
Williams, N., Busse, M., Cooper, R., Dodd, S., Dorkenoo, S., Doungsong, K., . . . Spencer, L. H. (2025). Effectiveness of a community-based rehabilitation programme following hip fracture: results from the Fracture in the Elderly Multidisciplinary Rehabilitation phase III (FEMuR III) randomised controlled trial. BMJ Open, 15(5), e091603. doi:10.1136/bmjopen-2024-091603
Carboprost versus Oxytocin as the first-line treatment of primary postpartum haemorrhage (COPE): protocol for a phase IV, double-blind, double-dummy, randomised controlled trial and economic analysis
Van Netten, C., Vallabhaneni, K., Hardwick, B., Anumba, D., Briley, A. L., Collins, P., . . . Weeks, A. (2025). Carboprost versus Oxytocin as the first-line treatment of primary postpartum haemorrhage (COPE): protocol for a phase IV, double-blind, double-dummy, randomised controlled trial and economic analysis. BMJ Open, 15(5), e101255. doi:10.1136/bmjopen-2025-101255
A community-based rehabilitation package following hip fracture: FEMuR III a multi-centre RCT, economic and process evaluation
Williams, N. H., Busse, M., Cooper, R., Davies, J., Dodd, S., Dorkenoo, S., . . . Temple, S. (2025). A community-based rehabilitation package following hip fracture: FEMuR III a multi-centre RCT, economic and process evaluation. Health Technology Assessment, 1-29. doi:10.3310/rbgd4741
2024
Perceived barriers and facilitators of staff recruiting participants to a randomised controlled trial of a community rehabilitation intervention following hip fracture
Harvey, K., Ralph, P., Spencer, L. H., Doungsong, K., Morrison, V., Lemmey, A. B., . . . Williams, N. (2024). Perceived barriers and facilitators of staff recruiting participants to a randomised controlled trial of a community rehabilitation intervention following hip fracture. Trials, 25. doi:10.1186/s13063-024-08655-z
Effectiveness and cost-effectiveness of a web-based cardiac rehabilitation programme for people with chronic stable angina: protocol for the ACTIVATE (Angina Controlled Trial Investigating the Value of the 'Activate your heart' Therapeutic E-intervention) randomised controlled trial.
Williams, N. H., Collins, B., Comerford, T. J., Dodd, S., Fisher, M., Hardwick, B., . . . Singh, S. J. (2024). Effectiveness and cost-effectiveness of a web-based cardiac rehabilitation programme for people with chronic stable angina: protocol for the ACTIVATE (Angina Controlled Trial Investigating the Value of the 'Activate your heart' Therapeutic E-intervention) randomised controlled trial.. BMJ open, 14(3), e084509. doi:10.1136/bmjopen-2024-084509
2023
CHronic hypERtension and L-citRulline studY (CHERRY): an Early-Phase Randomised Controlled Trial in Pregnancy.
Ormesher, L., Worton, S. A., Best, A., Dodd, S. R., Dempsey, A., Cottrell, E. C., . . . Myers, J. E. (2023). CHronic hypERtension and L-citRulline studY (CHERRY): an Early-Phase Randomised Controlled Trial in Pregnancy.. Reproductive sciences (Thousand Oaks, Calif.). doi:10.1007/s43032-023-01335-4
2022
Perfectionism and attitudes towards doping in athletes: the mediating role of achievement goal orientations
Hardwick, B., Madigan, D. J., Hill, A. P., Kumar, S., & Chan, D. K. C. (2022). Perfectionism and attitudes towards doping in athletes: the mediating role of achievement goal orientations. International Journal of Sport and Exercise Psychology, 20(3), 743-756. doi:10.1080/1612197x.2021.1891124
2020
Protocol for a definitive randomised controlled trial and economic evaluation of a community-based rehabilitation programme following hip fracture: fracture in the elderly multidisciplinary rehabilitation-phase III (FEMuR III).
Williams, N., Dodd, S., Hardwick, B., Clayton, D., Edwards, R. T., Charles, J. M., . . . Dorkenoo, S. (2020). Protocol for a definitive randomised controlled trial and economic evaluation of a community-based rehabilitation programme following hip fracture: fracture in the elderly multidisciplinary rehabilitation-phase III (FEMuR III).. BMJ Open, 10(10), e039791. doi:10.1136/bmjopen-2020-039791
Tocilizumab in patients with anti-TNF refractory juvenile idiopathic arthritis-associated uveitis (APTITUDE): a multicentre, single-arm, phase 2 trial
Ramanan, A. V., Dick, A. D., Guly, C., McKay, A., Jones, A. P., Hardwick, B., . . . APTITUDE Trial Management Group. (2020). Tocilizumab in patients with anti-TNF refractory juvenile idiopathic arthritis-associated uveitis (APTITUDE): a multicentre, single-arm, phase 2 trial. The Lancet Rheumatology, 2(3), e135-e141. doi:10.1016/s2665-9913(20)30008-4
A group intervention to improve quality of life for people with advanced dementia living in care homes: the Namaste feasibility cluster RCT
Froggatt, K., Best, A., Bunn, F., Burnside, G., Coast, J., Dunleavy, L., . . . Walshe, C. (2020). A group intervention to improve quality of life for people with advanced dementia living in care homes: the Namaste feasibility cluster RCT. Health Technology Assessment, 24(6), 1-140. doi:10.3310/hta24060
2019
Adalimumab in juvenile-idiopathic arthritis-associated uveitis (JIA-U): 5-year follow-up of the Bristol participants of the SYCAMORE trial.
Horton, S., Jones, A. P., Guly, C. M., Hardwick, B., Beresford, M. W., Lee, R. W. J., . . . Ramanan, A. V. (2019). Adalimumab in juvenile-idiopathic arthritis-associated uveitis (JIA-U): 5-year follow-up of the Bristol participants of the SYCAMORE trial.. American journal of ophthalmology. doi:10.1016/j.ajo.2019.06.007
Defining consensus opinion to develop randomised controlled trials in rare diseases using Bayesian design: An example of a proposed trial of adalimumab versus pamidronate for children with CNO/CRMO
Ramanan, A. V., Hampson, L. V., Lythgoe, H., Jones, A. P., Hardwick, B., Hind, H., . . . Beresford, M. W. (2019). Defining consensus opinion to develop randomised controlled trials in rare diseases using Bayesian design: An example of a proposed trial of adalimumab versus pamidronate for children with CNO/CRMO. PLOS ONE, 14(6), e0215739. doi:10.1371/journal.pone.0215739
Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT
Ramanan, A. V., Dick, A. D., Jones, A. P., Hughes, D. A., McKay, A., Rosala-Halas, A., . . . Grp, S. Y. C. A. M. O. R. E. S. (2019). Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT. HEALTH TECHNOLOGY ASSESSMENT, 23(15), 1-139. doi:10.3310/hta23150
Cost-Effectiveness Analysis of Adalimumab for the Treatment of Uveitis Associated with Juvenile Idiopathic Arthritis
Hughes, D. A., Culeddu, G., Plumpton, C. O., Wood, E., Dick, A. D., Jones, A. P., . . . Ramanan, A. V. (2019). Cost-Effectiveness Analysis of Adalimumab for the Treatment of Uveitis Associated with Juvenile Idiopathic Arthritis. Ophthalmology, 126(3), 415-424. doi:10.1016/j.ophtha.2018.09.043
2018
Namaste Care in nursing care homes for people with advanced dementia: protocol for a feasibility randomised controlled trial.
Froggatt, K., Patel, S., Perez Algorta, G., Bunn, F., Burnside, G., Coast, J., . . . Walshe, C. (2018). Namaste Care in nursing care homes for people with advanced dementia: protocol for a feasibility randomised controlled trial.. BMJ open, 8(11), e026531. doi:10.1136/bmjopen-2018-026531
A phase II trial protocol of Tocilizumab in anti-TNF refractory patients with JIA-associated uveitis (the APTITUDE trial)
Ramanan, A. V., Dick, A. D., Jones, A. P., Guly, C., Hardwick, B., Hickey, H., . . . Beresford, M. W. (2018). A phase II trial protocol of Tocilizumab in anti-TNF refractory patients with JIA-associated uveitis (the APTITUDE trial). BMC Rheumatology, 2(1). doi:10.1186/s41927-018-0010-2
2017
Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis
Ramanan, A. V., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot-Lacassagne, S., . . . Grp, S. Y. C. A. M. O. R. E. S. (2017). Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis. New England Journal of Medicine, 376(17), 1637-1646. doi:10.1056/NEJMoa1614160
2016
Assessing the feasibility of injectable growth-promoting therapy in Crohn’s disease
Altowati, M. A., Jones, A. P., Hickey, H., Williamson, P. R., Barakat, F. M., Plaatjies, N. C., . . . Sanderson, I. R. (2016). Assessing the feasibility of injectable growth-promoting therapy in Crohn’s disease. Pilot and Feasibility Studies, 2(1). doi:10.1186/s40814-016-0112-9
THU0213 Adalimumab in Combination with Methotrexate for The Treatment of Juvenile Idiopathic Arthritis Associated Uveitis: The Sycamore Trial
Ramanan, A. V., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot-Lacassagne, S., . . . Beresford, M. W. (2016). THU0213 Adalimumab in Combination with Methotrexate for The Treatment of Juvenile Idiopathic Arthritis Associated Uveitis: The Sycamore Trial. In Annals of the Rheumatic Diseases Vol. 75 (pp. 264-265). Elsevier BV. doi:10.1136/annrheumdis-2016-eular.6053
2014
A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial)
Ramanan, A. V., Dick, A. D., Benton, D., Compeyrot-Lacassagne, S., Dawoud, D., Hardwick, B., . . . Beresford, M. W. (2014). A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial). Trials, 15(1). doi:10.1186/1745-6215-15-14