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Leonardo de Oliveira Martins

Dr Leonardo de Oliveira Martins
BSc, MSc, PhD

Tenure Track Fellow in Health
Electrical Engineering and Electronics

Research outputs

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2025

Population structure and gene flux of Listeria monocytogenes ST121 reveal prophages as a candidate driver of adaptation and persistence in food production environments.

Gutiérrez, A. V., Matthews, M., Diaz, M., Le Viet, T., de Oliveira Martins, L., Jørgensen, F., . . . Gilmour, M. W. (2025). Population structure and gene flux of Listeria monocytogenes ST121 reveal prophages as a candidate driver of adaptation and persistence in food production environments.. Microb Genom, 11(4). doi:10.1099/mgen.0.001397

DOI
10.1099/mgen.0.001397
Journal article

Temporal dynamics of SARS-CoV-2 shedding in feces and saliva: a longitudinal study in Norfolk, United Kingdom during the 2021-2022 COVID-19 waves.

Kellingray, L., Savva, G. M., Garcia-Gutierrez, E., Snell, J., Romano, S., Yara, D. A., . . . Sayavedra, L. (2025). Temporal dynamics of SARS-CoV-2 shedding in feces and saliva: a longitudinal study in Norfolk, United Kingdom during the 2021-2022 COVID-19 waves.. Microbiology spectrum, e0319524. doi:10.1128/spectrum.03195-24

DOI
10.1128/spectrum.03195-24
Journal article

2024

2023

Repurposing an integrated national influenza platform for genomic surveillance of SARS-CoV-2 in Ghana: a molecular epidemiological analysis.

Asante, I. A., Hsu, S. N., Boatemaa, L., Kwasah, L., Adusei-Poku, M., Odoom, J. K., . . . Ampofo, W. K. (2023). Repurposing an integrated national influenza platform for genomic surveillance of SARS-CoV-2 in Ghana: a molecular epidemiological analysis.. The Lancet. Global health, 11(7), e1075-e1085. doi:10.1016/s2214-109x(23)00189-4

DOI
10.1016/s2214-109x(23)00189-4
Journal article

The SARS-CoV-2 Alpha variant was associated with increased clinical severity of COVID-19 in Scotland: A genomics-based retrospective cohort analysis.

Pascall, D. J., Vink, E., Blacow, R., Bulteel, N., Campbell, A., Campbell, R., . . . COVID-19 Genomics UK (COG-UK) Consortium. (2023). The SARS-CoV-2 Alpha variant was associated with increased clinical severity of COVID-19 in Scotland: A genomics-based retrospective cohort analysis.. PloS one, 18(4), e0284187. doi:10.1371/journal.pone.0284187

DOI
10.1371/journal.pone.0284187
Journal article

SARS-CoV-2 mutations on diagnostic gene targets in the second wave in Zimbabwe: A retrospective genomic analysis.

Nyagupe, C., de Oliveira Martins, L., Gumbo, H., Mashe, T., Takawira, T., Maeka, K. K., . . . Mavenyengwa, R. T. (2023). SARS-CoV-2 mutations on diagnostic gene targets in the second wave in Zimbabwe: A retrospective genomic analysis.. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 113(3), 141-147. doi:10.7196/samj.2023.v113i3.16762

DOI
10.7196/samj.2023.v113i3.16762
Journal article

2022

The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

Tegally, H., San, J. E., Cotten, M., Moir, M., Tegomoh, B., Mboowa, G., . . . Wilkinson, E. (2022). The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance. SCIENCE, 378(6615), 42-+. doi:10.1126/science.abq5358

DOI
10.1126/science.abq5358
Journal article

SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2

Eales, O., Page, A. J., de Oliveira Martins, L., Wang, H., Bodinier, B., Haw, D., . . . Elliott, P. (2022). SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2. BMC Infectious Diseases, 22(1). doi:10.1186/s12879-022-07628-4

DOI
10.1186/s12879-022-07628-4
Journal article

2021

SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2

DOI
10.1101/2021.12.17.21267925
Preprint

Genomic epidemiology and the role of international and regional travel in the SARS-CoV-2 epidemic in Zimbabwe: a retrospective study of routinely collected surveillance data.

Mashe, T., Takawira, F. T., de Oliveira Martins, L., Gudza-Mugabe, M., Chirenda, J., Munyanyi, M., . . . SARS-CoV-2 Research Group. (2021). Genomic epidemiology and the role of international and regional travel in the SARS-CoV-2 epidemic in Zimbabwe: a retrospective study of routinely collected surveillance data.. The Lancet. Global health, 9(12), e1658-e1666. doi:10.1016/s2214-109x(21)00434-4

DOI
10.1016/s2214-109x(21)00434-4
Journal article

Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study.

Twohig, K. A., Nyberg, T., Zaidi, A., Thelwall, S., Sinnathamby, M. A., Aliabadi, S., . . . COVID-19 Genomics UK (COG-UK) consortium. (2021). Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study.. The Lancet. Infectious diseases, 22(1), 35-42. doi:10.1016/s1473-3099(21)00475-8

DOI
10.1016/s1473-3099(21)00475-8
Journal article

Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England

Volz, E., Mishra, S., Chand, M., Barrett, J. C., Johnson, R., Geidelberg, L., . . . Ferguson, N. M. (2021). Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England. NATURE, 593(7858), 266-+. doi:10.1038/s41586-021-03470-x

DOI
10.1038/s41586-021-03470-x
Journal article

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Collier, D. A., De Marco, A., Ferreira, I. A. T. M., Meng, B., Datir, R. P., Walls, A. C., . . . Gupta, R. K. (2021). Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies. NATURE, 593(7857), 136-+. doi:10.1038/s41586-021-03412-7

DOI
10.1038/s41586-021-03412-7
Journal article

Phylogenomic Analyses Of 2,786 Genes In 158 Lineages Support a Root of The Eukaryotic Tree of Life Between Opisthokonts (Animals, Fungi and Their Microbial Relatives) and All Other Lineages

DOI
10.1101/2021.02.26.433005
Preprint

2020

Experimental evolution selects clinically relevant antibiotic resistance in biofilms but with collateral tradeoffs

Trampari, E., Holden, E., Wickham, G., Ravi, A., Prischi, F., Martins, L. D. O., . . . Webber, M. (2020). Experimental evolution selects clinically relevant antibiotic resistance in biofilms but with collateral tradeoffs. Access Microbiology, 2(1). doi:10.1099/acmi.mim2019.po0001

DOI
10.1099/acmi.mim2019.po0001
Journal article

2019

Taxonomic resolution of the ribosomal RNA operon in bacteria: Implications for its use with long read sequencing

DOI
10.1101/626093
Preprint

Antibiotics select for novel pathways of resistance in biofilms

DOI
10.1101/605212
Preprint

2017

Species Tree Estimation from Genome-Wide Data with guenomu.

de Oliveira Martins, L., & Posada, D. (2017). Species Tree Estimation from Genome-Wide Data with guenomu.. In Unknown Book (Vol. 1525, pp. 461-478). doi:10.1007/978-1-4939-6622-6_18

DOI
10.1007/978-1-4939-6622-6_18
Chapter

2016

2015

Infinitely Long Branches and an Informal Test of Common Ancestry

DOI
10.1101/023903
Preprint

Species Tree Estimation from Genome-wide Data with Guenomu

DOI
10.1101/023861
Preprint

<i>SimPhy</i>: Phylogenomic Simulation of Gene, Locus and Species Trees

DOI
10.1101/021709
Preprint

Phylogenetic Likelihood

de Oliveira Martins, L., Mallo, D., & Posada, D. (n.d.). Phylogenetic Likelihood. Wiley. doi:10.1002/9780470015902.a0005141

DOI
10.1002/9780470015902.a0005141
Other

2014

Estimation of Species Trees

Mallo, D., de Oliveira Martins, L., & Posada, D. (n.d.). Estimation of Species Trees. Wiley. doi:10.1002/9780470015902.a0025781

DOI
10.1002/9780470015902.a0025781
Other

2013

2012

2010

Lineage-specific positive selection at the merozoite surface protein 1 (msp1) locus of Plasmodium vivax and related simian malaria parasites.

Sawai, H., Otani, H., Arisue, N., Palacpac, N., de Oliveira Martins, L., Pathirana, S., . . . Tanabe, K. (2010). Lineage-specific positive selection at the merozoite surface protein 1 (msp1) locus of Plasmodium vivax and related simian malaria parasites.. BMC evolutionary biology, 10, 52. doi:10.1186/1471-2148-10-52

DOI
10.1186/1471-2148-10-52
Journal article

Distribution of distances between topologies and its effect on detection of phylogenetic recombination

de Oliveira Martins, L., & Kishino, H. (2010). Distribution of distances between topologies and its effect on detection of phylogenetic recombination. Annals of the Institute of Statistical Mathematics, 62(1), 145-159. doi:10.1007/s10463-009-0259-8

DOI
10.1007/s10463-009-0259-8
Journal article

2008

Evolutionary Dynamics of HIV-1 BF and CB Recombinants and Its Parental Counterparts in South America

Evolutionary Dynamics of HIV-1 BF and CB Recombinants and Its Parental Counterparts in South America (2008). Retrovirology: Research and Treatment, 1, 1-14. doi:10.4137/rrt.s1045

DOI
10.4137/rrt.s1045
Journal article

2007

2006

Evolutionary relationships of deep-sea mussels inferred by mitochondrial DNA sequences

Iwasaki, H., Kyuno, A., Shintaku, M., Fujita, Y., Fujiwara, Y., Fujikura, K., . . . Miyazaki, J. -I. (2006). Evolutionary relationships of deep-sea mussels inferred by mitochondrial DNA sequences. Marine Biology, 149(5), 1111-1122. doi:10.1007/s00227-006-0268-6

DOI
10.1007/s00227-006-0268-6
Journal article

2005

Phylogeography of loaches of the genus lefua (balitoridae, cypriniformes) inferred from mitochondrial DNA sequences.

Mihara, M., Sakai, T., Nakao, K., Martins, L. D. O., Hosoya, K., & Miyazaki, J. -I. (2005). Phylogeography of loaches of the genus lefua (balitoridae, cypriniformes) inferred from mitochondrial DNA sequences.. Zoological science, 22(2), 157-168. doi:10.2108/zsj.22.157

DOI
10.2108/zsj.22.157
Journal article