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Lance Turtle

Professor Lance Turtle
BSc PhD MBBS FRCP DTMH

Chair and Honorary Consultant Physician in Infectious Diseases; Deputy head of Department of Clinical Infection, Microbiology and Immunology
Clinical Infection, Microbiology & Immunology

Contact

Lance.Turtle@liverpool.ac.uk

+44 (0)151 795 7554

+44 (0)151 795 7554 Ext. 57554

Research outputs

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2026

Yellow fever vaccine minimum fractional dosing does not extend to infants

Turtle, L. (2026). Yellow fever vaccine minimum fractional dosing does not extend to infants. The Lancet, 407(10527), 470-471. doi:10.1016/s0140-6736(25)02364-5

DOI
10.1016/s0140-6736(25)02364-5
Journal article

2025

Monkeypox virus-neutralising antibodies detected against Clade Ib and Clade IIb in healthy individuals following MVA-BN vaccination

DOI
10.1101/2025.09.17.25335983
Preprint

MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines

Amini, A., Garner, L. C., Shaw, R. H., Kelly, N. W., Adele, S., Skelly, D. T., . . . Nguyen-Van-Tam, J. S. (2025). MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines. Science Immunology, 10(110). doi:10.1126/sciimmunol.adu3337

DOI
10.1126/sciimmunol.adu3337
Journal article

Dynamic impact of bivalent COVID-19 vaccine boosters on systemic and mucosal immunity– an observational cohort study

DOI
10.21203/rs.3.rs-6377378/v1
Preprint

2024

Identifying and reducing risks of neurological complications associated with vaccination

Handunnetthi, L., Ramasamy, M. N., Turtle, L., & Hunt, D. P. J. (2024). Identifying and reducing risks of neurological complications associated with vaccination. Nature Reviews Neurology, 20(9), 541-554. doi:10.1038/s41582-024-01000-7

DOI
10.1038/s41582-024-01000-7
Journal article

HAP-FAST: a feasibility study incorporating qualitative, mechanistic and costing sub-studies alongside a randomised pilot trial comparing chest x-ray to low-dose CT scan and empirical antibiotics to antibiotics guided by the BIOFIRE® FILM ARRAY® pneumonia <i>plus</i> panel in adults with suspected non-ventilator-associated hospital-acquired pneumonia

Shafiqa, N., Aston, S., Howard, A., Turtle, L., Abrams, S., Young, B., . . . Wootton, D. G. (2024). HAP-FAST: a feasibility study incorporating qualitative, mechanistic and costing sub-studies alongside a randomised pilot trial comparing chest x-ray to low-dose CT scan and empirical antibiotics to antibiotics guided by the BIOFIRE® FILM ARRAY® pneumonia <i>plus</i> panel in adults with suspected non-ventilator-associated hospital-acquired pneumonia. BMJ Open, 14(7), e088490. doi:10.1136/bmjopen-2024-088490

DOI
10.1136/bmjopen-2024-088490
Journal article

Sequential Infection with Influenza A Virus Followed by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Leads to More Severe Disease and Encephalitis in a Mouse Model of COVID-19.

Clark, J. J., Penrice-Randal, R., Sharma, P., Dong, X., Pennington, S. H., Marriott, A. E., . . . Stewart, J. P. (2024). Sequential Infection with Influenza A Virus Followed by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Leads to More Severe Disease and Encephalitis in a Mouse Model of COVID-19.. Viruses, 16(6), 863. doi:10.3390/v16060863

DOI
10.3390/v16060863
Journal article

Changes in hospital mortality in patients with cancer during the COVID-19 pandemic (ISARIC-CCP-UK): a prospective, multicentre cohort study

Turtle, L., Elliot, S., Drake, T. M., Thorpe, M., Khoury, E. G., Greenhalf, W., . . . Palmieri, C. (2024). Changes in hospital mortality in patients with cancer during the COVID-19 pandemic (ISARIC-CCP-UK): a prospective, multicentre cohort study. The Lancet Oncology, 25(5), 636-648. doi:10.1016/s1470-2045(24)00107-4

DOI
10.1016/s1470-2045(24)00107-4
Journal article

Can self-testing be enhanced to hasten safe return of healthcare workers in pandemics? Random order, open label trial using two manufacturers’ SARS-CoV-2 lateral flow devices concurrently

DOI
10.1101/2024.04.04.24305332
Preprint

2023

Damage-associated cellular markers in the clinical and pathogenic profile of vaccine-induced immune thrombotic thrombocytopenia.

Abrams, S. T., Du, M., Shaw, R. J., Johnson, C., McGuinness, D., Schofield, J., . . . Toh, C. -H. (2023). Damage-associated cellular markers in the clinical and pathogenic profile of vaccine-induced immune thrombotic thrombocytopenia.. Journal of thrombosis and haemostasis : JTH, S1538-7836(23)00873-5. doi:10.1016/j.jtha.2023.12.008

DOI
10.1016/j.jtha.2023.12.008
Journal article

Natural immune boosting can cause synchrony in susceptibility and outbreaks of respiratory infections with rapidly waning immunity

DOI
10.1101/2023.11.23.23298952
Preprint

T cell immune memory after covid-19 and vaccination

Wang, L., Nicols, A., Turtle, L., Richter, A., Duncan, C. J. A., Dunachie, S. J., . . . Payne, R. P. (2023). T cell immune memory after covid-19 and vaccination. BMJ Medicine, 2(1), e000468. doi:10.1136/bmjmed-2022-000468

DOI
10.1136/bmjmed-2022-000468
Journal article

CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study.

Neale, I., Ali, M., Kronsteiner, B., Longet, S., Abraham, P., Deeks, A. S., . . . PITCH Consortium. (2023). CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study.. mBio, e0121223. doi:10.1128/mbio.01212-23

DOI
10.1128/mbio.01212-23
Journal article

HLA-E-restricted SARS-CoV-2-specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation

Yang, H., Sun, H., Brackenridge, S., Zhuang, X., Wing, P. A. C., Quastel, M., . . . McMichael, A. J. (2023). HLA-E-restricted SARS-CoV-2-specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation. SCIENCE IMMUNOLOGY, 8(84). doi:10.1126/sciimmunol.abl8881

DOI
10.1126/sciimmunol.abl8881
Journal article

Obesity Differs from Diabetes Mellitus in Antibody and T Cell Responses Post COVID-19 Recovery

DOI
10.1101/2023.06.14.23291375
Preprint

CD4+ and CD8+ T cell and antibody correlates of protection against Delta vaccine breakthrough infection: A nested case-control study within the PITCH study

DOI
10.1101/2023.02.16.23285748
Preprint

High number of SARS-CoV-2 persistent infections uncovered through genetic analysis of samples from a large community-based surveillance study

DOI
10.1101/2023.01.29.23285160
Preprint

Omicron BA.1/BA.2 infections in triple-vaccinated individuals enhance a diverse repertoire of mucosal and blood immune responses

DOI
10.1101/2023.01.28.23285084
Preprint

SARS-CoV-2 antibody responses associate with sex, age and disease severity in previously uninfected people admitted to hospital with COVID-19: An ISARIC4C prospective study

Parker, E., Thomas, J., Roper, K. J., Ijaz, S., Edwards, T., Marchesin, F., . . . Pollakis, G. (2023). SARS-CoV-2 antibody responses associate with sex, age and disease severity in previously uninfected people admitted to hospital with COVID-19: An ISARIC4C prospective study. Frontiers in Immunology, 14. doi:10.3389/fimmu.2023.1146702

DOI
10.3389/fimmu.2023.1146702
Journal article

2022

Changing patterns of SARS-CoV-2 infection through Delta and Omicron waves by vaccination status, previous infection and neighbourhood deprivation: a cohort analysis of 2.7 M people

Green, M. A., Hungerford, D. J., Hughes, D. M., Garcia-Fiñana, M., Turtle, L., Cheyne, C., . . . Buchan, I. (2022). Changing patterns of SARS-CoV-2 infection through Delta and Omicron waves by vaccination status, previous infection and neighbourhood deprivation: a cohort analysis of 2.7 M people. BMC Infectious Diseases, 22(1). doi:10.1186/s12879-022-07878-2

DOI
10.1186/s12879-022-07878-2
Journal article

Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study

Reyes, L. F., Murthy, S., Garcia-Gallo, E., Merson, L., Ibáñez-Prada, E. D., Rello, J., . . . Zucman, D. (2022). Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study. Critical Care, 26(1). doi:10.1186/s13054-022-04155-1

DOI
10.1186/s13054-022-04155-1
Journal article

SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2

Eales, O., Page, A. J., de Oliveira Martins, L., Wang, H., Bodinier, B., Haw, D., . . . Elliott, P. (2022). SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2. BMC Infectious Diseases, 22(1). doi:10.1186/s12879-022-07628-4

DOI
10.1186/s12879-022-07628-4
Journal article

Neurological manifestations of scrub typhus infection: A systematic review and meta-analysis of clinical features and case fatality

Alam, A. M., Gillespie, C. S., Goodall, J., Damodar, T., Turtle, L., Vasanthapuram, R., . . . Michael, B. D. (2022). Neurological manifestations of scrub typhus infection: A systematic review and meta-analysis of clinical features and case fatality. PLOS Neglected Tropical Diseases, 16(11), e0010952. doi:10.1371/journal.pntd.0010952

DOI
10.1371/journal.pntd.0010952
Journal article

Viral Coinfections in Hospitalized Coronavirus Disease 2019 Patients Recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK Study

Vink, E., Davis, C., MacLean, A., Pascall, D., McDonald, S. E., Gunson, R., . . . Ho, A. (2022). Viral Coinfections in Hospitalized Coronavirus Disease 2019 Patients Recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK Study. OPEN FORUM INFECTIOUS DISEASES, 9(11). doi:10.1093/ofid/ofac531

DOI
10.1093/ofid/ofac531
Journal article

Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19

Kotanidis, C. P., Xie, C., Alexander, D., Rodrigues, J. C. L., Burnham, K., Mentzer, A., . . . Lin, W. -H. (2022). Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19. The Lancet Digital Health, 4(10), e705-e716. doi:10.1016/s2589-7500(22)00132-7

DOI
10.1016/s2589-7500(22)00132-7
Journal article

An International Comparison of Presentation, Outcomes and CORONET Predictive Score Performance in Patients with Cancer Presenting with COVID-19 across Different Pandemic Waves

Wysocki, O., Zhou, C., Rogado, J., Huddar, P., Shotton, R., Tivey, A., . . . Co-Care, E. S. M. O. (2022). An International Comparison of Presentation, Outcomes and CORONET Predictive Score Performance in Patients with Cancer Presenting with COVID-19 across Different Pandemic Waves. Cancers, 14(16). doi:10.3390/cancers14163931

DOI
10.3390/cancers14163931
Journal article

Nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

DOI
10.1101/2022.09.09.22279759
Preprint

The aerobiology of SARS-CoV-2 in UK hospitals and the impact of aerosol generating procedures

DOI
10.1101/2022.09.07.22279662
Preprint

Outcome of COVID-19 in hospitalised immunocompromised patients: an analysis of the WHO ISARIC CCP-UK prospective cohort study

DOI
10.1101/2022.08.08.22278576
Preprint

Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study

Evans, R. A., Leavy, O. C., Richardson, M., Elneima, O., McAuley, H. J. C., Shikotra, A., . . . Zongo, O. (2022). Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study. The Lancet Respiratory Medicine, 10(8), 761-775. doi:10.1016/s2213-2600(22)00127-8

DOI
10.1016/s2213-2600(22)00127-8
Journal article

Mapping of SARS-CoV-2 IgM and IgG in gingival crevicular fluid: Antibody dynamics and linkage to severity of COVID-19 in hospital inpatients

Ijaz, S., Dicks, S., Jegatheesan, K., Parker, E., Katsanovskaja, K., Vink, E., . . . Tedder, R. S. (2022). Mapping of SARS-CoV-2 IgM and IgG in gingival crevicular fluid: Antibody dynamics and linkage to severity of COVID-19 in hospital inpatients. Journal of Infection, 85(2), 152-160. doi:10.1016/j.jinf.2022.05.033

DOI
10.1016/j.jinf.2022.05.033
Journal article

Comparison of two T-cell assays to evaluate T-cell responses to SARS-CoV-2 following vaccination in naïve and convalescent healthcare workers

Phillips, E., Adele, S., Malone, T., Deeks, A., Stafford, L., Dobson, S. L., . . . Dunachie, S. J. (2022). Comparison of two T-cell assays to evaluate T-cell responses to SARS-CoV-2 following vaccination in naïve and convalescent healthcare workers. Clinical and Experimental Immunology, 209(1), 90-98. doi:10.1093/cei/uxac042

DOI
10.1093/cei/uxac042
Journal article

An international observational study to assess the impact of the Omicron variant emergence on the clinical epidemiology of COVID-19 in hospitalised patients

DOI
10.1101/2022.06.22.22276764
Preprint

Deep proteomics network and machine learning analysis of human cerebrospinal fluid in Japanese encephalitis virus infection

DOI
10.1101/2022.06.19.496758
Preprint

Evolution of long-term vaccine induced and hybrid immunity in healthcare workers after different COVID-19 vaccination regimens: a longitudinal observational cohort study

DOI
10.1101/2022.06.06.22275865
Preprint

A systematic review of brain imaging findings in neurological infection with Japanese encephalitis virus compared with Dengue virus.

Pichl, T., Wedderburn, C. J., Hoskote, C., Turtle, L., & Bharucha, T. (2022). A systematic review of brain imaging findings in neurological infection with Japanese encephalitis virus compared with Dengue virus.. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 119, 102-110. doi:10.1016/j.ijid.2022.03.010

DOI
10.1016/j.ijid.2022.03.010
Journal article

Analysis of SARS-CoV-2 in Nasopharyngeal Samples from Patients with COVID-19 Illustrates Population Variation and Diverse Phenotypes, Placing the Growth Properties of Variants of Concern in Context with Other Lineages

Prince, T., Dong, X., Penrice-Randal, R., Randle, N., Hartley, C., Goldswain, H., . . . Hiscox, J. A. (2022). Analysis of SARS-CoV-2 in Nasopharyngeal Samples from Patients with COVID-19 Illustrates Population Variation and Diverse Phenotypes, Placing the Growth Properties of Variants of Concern in Context with Other Lineages. mSphere, 7(3). doi:10.1128/msphere.00913-21

DOI
10.1128/msphere.00913-21
Journal article

Analysis of SARS-CoV-2 known and novel subgenomic mRNAs in cell culture, animal model, and clinical samples using LeTRS, a bioinformatic tool to identify unique sequence identifiers

Dong, X., Penrice-Randal, R., Goldswain, H., Prince, T., Randle, N., Donovan-Banfield, I., . . . Hiscox, J. A. (2022). Analysis of SARS-CoV-2 known and novel subgenomic mRNAs in cell culture, animal model, and clinical samples using LeTRS, a bioinformatic tool to identify unique sequence identifiers. GigaScience, 11. doi:10.1093/gigascience/giac045

DOI
10.1093/gigascience/giac045
Journal article

Establishment of CORONET, COVID-19 Risk in Oncology Evaluation Tool, to Identify Patients With Cancer at Low Versus High Risk of Severe Complications of COVID-19 Disease On Presentation to Hospital.

Lee, R. J., Wysocki, O., Zhou, C., Shotton, R., Tivey, A., Lever, L., . . . Armstrong, A. C. (2022). Establishment of CORONET, COVID-19 Risk in Oncology Evaluation Tool, to Identify Patients With Cancer at Low Versus High Risk of Severe Complications of COVID-19 Disease On Presentation to Hospital.. JCO clinical cancer informatics, 6, e2100177. doi:10.1200/cci.21.00177

DOI
10.1200/cci.21.00177
Journal article

Differences in Outcomes and Factors Associated With Mortality Among Patients With SARS-CoV-2 Infection and Cancer Compared With Those Without Cancer

Khoury, E., Nevitt, S., Madsen, W. R., Turtle, L., Davies, G., & Palmieri, C. (2022). Differences in Outcomes and Factors Associated With Mortality Among Patients With SARS-CoV-2 Infection and Cancer Compared With Those Without Cancer. JAMA Network Open, 5(5), e2210880. doi:10.1001/jamanetworkopen.2022.10880

DOI
10.1001/jamanetworkopen.2022.10880
Journal article

Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission

Relph, K. A., Russell, C. D., Fairfield, C. J., Turtle, L., de Silva, T. I., Siggins, M. K., . . . Young, P. (2022). Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission. Open Forum Infectious Diseases, 9(5). doi:10.1093/ofid/ofac179

DOI
10.1093/ofid/ofac179
Journal article

SARS-CoV-2-Specific T Cell Responses Are Not Associated with Protection against Reinfection in Hemodialysis Patients

Shankar, S., Beckett, J., Tipton, T., Ogbe, A., Kasanyinga, M., Dold, C., . . . Klenerman, P. (2022). SARS-CoV-2-Specific T Cell Responses Are Not Associated with Protection against Reinfection in Hemodialysis Patients. Journal of the American Society of Nephrology, 33(5), 883-887. doi:10.1681/asn.2021121587

DOI
10.1681/asn.2021121587
Journal article

Evaluation of Eight Lateral Flow Tests for the detection of anti-SARS-CoV-2 antibodies in a vaccinated population

DOI
10.1101/2022.04.04.22273232
Preprint

Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study

Närhi, F., Moonesinghe, S. R., Shenkin, S. D., Drake, T. M., Mulholland, R. H., Donegan, C., . . . Young, P. (2022). Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study. The Lancet Digital Health, 4(4), e220-e234. doi:10.1016/s2589-7500(22)00018-8

DOI
10.1016/s2589-7500(22)00018-8
Journal article

Hospital admission for symptomatic COVID-19 and impact of vaccination: analysis of linked data from the Coronavirus Clinical Information Network and the National Immunisation Management Service

Egan, C., Turtle, L., Thorpe, M., Harrison, E. M., Semple, M. G., & Docherty, A. B. (2022). Hospital admission for symptomatic COVID-19 and impact of vaccination: analysis of linked data from the Coronavirus Clinical Information Network and the National Immunisation Management Service. ANAESTHESIA. doi:10.1111/anae.15677

DOI
10.1111/anae.15677
Journal article

Comparison of two T cell assays to evaluate T cell responses to SARS-CoV-2 following vaccination in naïve and convalescent healthcare workers

DOI
10.1101/2022.02.05.22270447
Preprint

Spatial Growth Rate of Emerging SARS-CoV-2 Lineages in England, September 2020–December 2021

DOI
10.1101/2022.02.02.22270110
Preprint

Lineage replacement and evolution captured by three years of the United Kingdom Covid Infection Survey

DOI
10.1101/2022.01.05.21268323
Preprint

The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism

DOI
10.1101/2022.01.03.21268111
Preprint

Flavivirus cross-reactivity would explain the apparent findings of Japanese encephalitis virus infection in Nigeria

Bharucha, T., Zitzmann, N., Newton, P., Dubot-Pérès, A., & Turtle, L. (2022). Flavivirus cross-reactivity would explain the apparent findings of Japanese encephalitis virus infection in Nigeria. Journal of Immunoassay and Immunochemistry, 43(4), 463-465. doi:10.1080/15321819.2022.2039184

DOI
10.1080/15321819.2022.2039184
Journal article

Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol

Knight, S. R., Gupta, R. K., Ho, A., Pius, R., Buchan, I., Carson, G., . . . Harrison, E. M. (2022). Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol. Thorax, 77(6), 606-615. doi:10.1136/thoraxjnl-2021-217629

DOI
10.1136/thoraxjnl-2021-217629
Journal article

T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study

Angyal, A., Longet, S., Moore, S. C., Payne, R. P., Harding, A., Tipton, T., . . . Chalk, J. (2022). T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study. The Lancet Microbe, 3(1), e21-e31. doi:10.1016/s2666-5247(21)00275-5

DOI
10.1016/s2666-5247(21)00275-5
Journal article

2021

A comprehensive systematic review and meta-analysis of the global data involving 61,532 cancer patients with SARS-CoV-2 infection

DOI
10.1101/2021.12.18.21267261
Preprint

The value of open-source clinical science in pandemic response: lessons from ISARIC

Abbas, A., Abdukahil, S. A., Abdulkadir, N. N., Abe, R., Abel, L., Absil, L., . . . Zucman, D. (2021). The value of open-source clinical science in pandemic response: lessons from ISARIC. The Lancet Infectious Diseases, 21(12), 1623-1624. doi:10.1016/s1473-3099(21)00565-x

DOI
10.1016/s1473-3099(21)00565-x
Journal article

Antiviral activity of Molnupiravir precursor NHC against SARS-CoV-2 Variants of Concern (VOCs) and implications for the therapeutic window and resistance

DOI
10.1101/2021.11.23.469695
Preprint

Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study

Evans, R. A., McAuley, H. J. C., Harrison, E. M., Shikotra, A., Singapuri, A., Sereno, M., . . . Zongo, O. (2021). Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study. The Lancet Respiratory Medicine, 9(11), 1275-1287. doi:10.1016/s2213-2600(21)00383-0

DOI
10.1016/s2213-2600(21)00383-0
Journal article

Detection of Serum Cross-Reactive Antibodies and Memory Response to SARS-CoV-2 in Prepandemic and Post–COVID-19 Convalescent Samples

Shrwani, K., Sharma, R., Krishnan, M., Jones, T., Mayora-Neto, M., Cantoni, D., . . . Zhang, Q. (2021). Detection of Serum Cross-Reactive Antibodies and Memory Response to SARS-CoV-2 in Prepandemic and Post–COVID-19 Convalescent Samples. The Journal of Infectious Diseases, 224(8), 1305-1315. doi:10.1093/infdis/jiab333

DOI
10.1093/infdis/jiab333
Journal article

LBA60 Prospective data of >20,000 hospitalised patients with cancer and COVID-19 derived from the International Severe Acute Respiratory and emerging Infections Consortium WHO Coronavirus Clinical Characterisation Consortium: CCP-CANCER UK

Palmieri, C., Turtle, L., Drake, T., Harrison, E., Docherty, A., Greenhalf, B., . . . Semple, M. M. G. (2021). LBA60 Prospective data of >20,000 hospitalised patients with cancer and COVID-19 derived from the International Severe Acute Respiratory and emerging Infections Consortium WHO Coronavirus Clinical Characterisation Consortium: CCP-CANCER UK. In Annals of Oncology Vol. 32 (pp. s1337). Elsevier. doi:10.1016/j.annonc.2021.08.2141

DOI
10.1016/j.annonc.2021.08.2141
Conference Paper

Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol

Sigfrid, L., Drake, T. M., Pauley, E., Jesudason, E. C., Olliaro, P., Lim, W. S., . . . Scott, J. T. (2021). Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol. The Lancet Regional Health - Europe, 8, 100186. doi:10.1016/j.lanepe.2021.100186

DOI
10.1016/j.lanepe.2021.100186
Journal article

Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study.

Twohig, K. A., Nyberg, T., Zaidi, A., Thelwall, S., Sinnathamby, M. A., Aliabadi, S., . . . COVID-19 Genomics UK (COG-UK) consortium. (2021). Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study.. The Lancet. Infectious diseases, 22(1), 35-42. doi:10.1016/s1473-3099(21)00475-8

DOI
10.1016/s1473-3099(21)00475-8
Journal article

Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study

Russell, C. D., Fairfield, C. J., Drake, T. M., Turtle, L., Seaton, R. A., Wootton, D. G., . . . Young, P. (2021). Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study. The Lancet Microbe, 2(8), e354-e365. doi:10.1016/s2666-5247(21)00090-2

DOI
10.1016/s2666-5247(21)00090-2
Journal article

Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study

Drake, T. M., Riad, A. M., Fairfield, C. J., Egan, C., Knight, S. R., Pius, R., . . . Young, P. (2021). Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study. The Lancet, 398(10296), 223-237. doi:10.1016/s0140-6736(21)00799-6

DOI
10.1016/s0140-6736(21)00799-6
Journal article

Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK

Docherty, A. B., Mulholland, R. H., Lone, N. I., Cheyne, C. P., De Angelis, D., Diaz-Ordaz, K., . . . Young, P. (2021). Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK. The Lancet Respiratory Medicine, 9(7), 773-785. doi:10.1016/s2213-2600(21)00175-2

DOI
10.1016/s2213-2600(21)00175-2
Journal article

Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study

Drake, T. M., Fairfield, C. J., Pius, R., Knight, S. R., Norman, L., Girvan, M., . . . Young, P. (2021). Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study. The Lancet Rheumatology, 3(7), e498-e506. doi:10.1016/s2665-9913(21)00104-1

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Journal article

Obesity, Ethnicity, and Risk of Critical Care, Mechanical Ventilation, and Mortality in Patients Admitted to Hospital with COVID‐19: Analysis of the ISARIC CCP‐UK Cohort

Yates, T., Zaccardi, F., Islam, N., Razieh, C., Gillies, C. L., Lawson, C. A., . . . Khunti, K. (2021). Obesity, Ethnicity, and Risk of Critical Care, Mechanical Ventilation, and Mortality in Patients Admitted to Hospital with COVID‐19: Analysis of the ISARIC CCP‐UK Cohort. Obesity, 29(7), 1223-1230. doi:10.1002/oby.23178

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10.1002/oby.23178
Journal article

Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19 a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK

Bloom, C. I., Drake, T. M., Docherty, A. B., Lipworth, B. J., Johnston, S. L., Nguyen-Van-Tam, J. S., . . . Openshaw, P. J. M. (2021). Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19 a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK. LANCET RESPIRATORY MEDICINE, 9(7), 699-711. doi:10.1016/S2213-2600(21)00013-8

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10.1016/S2213-2600(21)00013-8
Journal article

Kinetics of the neutralising antibody response in patients with hand, foot, and mouth disease caused by EV-A71: A longitudinal cohort study in Zhengzhou during 2017-2019

Qiu, Q., Zhou, J., Cheng, Y., Zhou, Y., Liang, L., Cui, P., . . . Yu, H. (2021). Kinetics of the neutralising antibody response in patients with hand, foot, and mouth disease caused by EV-A71: A longitudinal cohort study in Zhengzhou during 2017-2019. EBioMedicine, 68, 103398. doi:10.1016/j.ebiom.2021.103398

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Journal article

Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England

Volz, E., Mishra, S., Chand, M., Barrett, J. C., Johnson, R., Geidelberg, L., . . . Ferguson, N. M. (2021). Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England. Nature, 593(7858), 266-269. doi:10.1038/s41586-021-03470-x

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Journal article

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Collier, D. A., De Marco, A., Ferreira, I. A. T. M., Meng, B., Datir, R. P., Walls, A. C., . . . Gupta, R. K. (2021). Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies. Nature, 593(7857), 136-141. doi:10.1038/s41586-021-03412-7

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Journal article

Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study

Gupta, R. K., Harrison, E. M., Ho, A., Docherty, A. B., Knight, S. R., van Smeden, M., . . . Young, P. (2021). Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study. The Lancet Respiratory Medicine, 9(4), 349-359. doi:10.1016/s2213-2600(20)30559-2

DOI
10.1016/s2213-2600(20)30559-2
Journal article

Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol

Sigfrid, L., Drake, T. M., Pauley, E., Jesudason, E. C., Olliaro, P., Lim, W. S., . . . Scott, J. T. (2021). Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol. doi:10.1101/2021.03.18.21253888

DOI
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Journal article

Prospective observational study of SARS-CoV-2 infection, transmission and immunity in a cohort of households in Liverpool City Region, UK (COVID-LIV): a study protocol

Setiabudi, W., Hungerford, D., Subramaniam, K., Vaselli, N. M., Shaw, V. E., Wilton, M., . . . French, N. (2021). Prospective observational study of SARS-CoV-2 infection, transmission and immunity in a cohort of households in Liverpool City Region, UK (COVID-LIV): a study protocol. BMJ Open, 11(3), e048317. doi:10.1136/bmjopen-2020-048317

DOI
10.1136/bmjopen-2020-048317
Journal article

What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? A harmonised, global longitudinal observational study protocol.

Sigfrid, L., Cevik, M., Jesudason, E., Lim, W. S., Rello, J., Amuasi, J., . . . Scott, J. T. (2021). What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? A harmonised, global longitudinal observational study protocol.. BMJ Open, 11(3), e043887. doi:10.1136/bmjopen-2020-043887

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Journal article

Identification and quantification of SARS-CoV-2 leader subgenomic mRNA gene junctions in nasopharyngeal samples shows phasic transcription in animal models of COVID-19 and dysregulation at later time points that can also be identified in humans

Dong, X., Penrice-Randal, R., Goldswain, H., Prince, T., Randle, N., Salguero, J., . . . Hiscox, J. A. (2021). Identification and quantification of SARS-CoV-2 leader subgenomic mRNA gene junctions in nasopharyngeal samples shows phasic transcription in animal models of COVID-19 and dysregulation at later time points that can also be identified in humans. doi:10.1101/2021.03.03.433753

DOI
10.1101/2021.03.03.433753
Journal article

SARS-CoV-2 B.1.1.7 sensitivity to mRNA vaccine-elicited, convalescent and monoclonal antibodies

DOI
10.1101/2021.01.19.21249840
Preprint

Changes in symptomatology, re-infection and transmissibility associated with SARS-CoV-2 variant B.1.1.7: an ecological study

DOI
10.1101/2021.01.28.21250680
Preprint

Haematological malignancy and nosocomial transmission are associated with an increased risk of death from COVID-19: results of a multi-center UK cohort.

Bhogal, T., Khan, U. T., Lee, R., Stockdale, A., Hesford, C., Potti-Dhananjaya, V., . . . Palmieri, C. (2021). Haematological malignancy and nosocomial transmission are associated with an increased risk of death from COVID-19: results of a multi-center UK cohort.. Leukemia & lymphoma, 1-16. doi:10.1080/10428194.2021.1876865

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10.1080/10428194.2021.1876865
Journal article

Do antibody positive healthcare workers have lower SARS-CoV-2 infection rates than antibody negative healthcare workers? Large multi-centre prospective cohort study (the SIREN study), England: June to November 2020

DOI
10.1101/2021.01.13.21249642
Preprint

Early analysis of a potential link between viral load and the N501Y mutation in the SARS-COV-2 spike protein

DOI
10.1101/2021.01.12.20249080
Preprint

Guillain-Barré syndrome during the Zika virus outbreak in Northeast Brazil: An observational cohort study

Leonhard, S. E., Halstead, S., Lant, S. B., Militão de Albuquerque, M. D. F. P., de Brito, C. A. A., de Albuquerque, L. B. B., . . . Brito Ferreira, M. L. (2021). Guillain-Barré syndrome during the Zika virus outbreak in Northeast Brazil: An observational cohort study. Journal of the Neurological Sciences, 420, 117272. doi:10.1016/j.jns.2020.117272

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10.1016/j.jns.2020.117272
Journal article

Molecular mechanisms underlying attenuation of live attenuated Japanese encephalitis virus vaccine SA14-14-2

DOI
10.1101/2021.01.14.426643
Preprint

Genomic epidemiology of the SARS-CoV-2 epidemic in Zimbabwe: Role of international travel and regional migration in spread

DOI
10.1101/2021.01.04.20232520
Preprint

Transmission of SARS-CoV-2 Lineage B.1.1.7 in England: Insights from linking epidemiological and genetic data

DOI
10.1101/2020.12.30.20249034
Preprint

T-Cell and Antibody Responses to First BNT162b2 Vaccine Dose in Previously SARS-CoV-2-Infected and Infection-Naive UK Healthcare Workers: A Multicentre, Prospective, Observational Cohort Study

DOI
10.2139/ssrn.3820576
Preprint

The Impact of Viral Mutations on Recognition by SARS-CoV-2 Specific T-Cells

DOI
10.2139/ssrn.3844713
Preprint

2020

Changes in UK hospital mortality in the first wave of COVID-19: the ISARIC WHO Clinical Characterisation Protocol prospective multicentre observational cohort study

Docherty, A. B., Mulholland, R. H., Lone, N. I., Cheyne, C. P., De Angelis, D., Diaz-Ordaz, K., . . . Semple, M. G. (2020). Changes in UK hospital mortality in the first wave of COVID-19: the ISARIC WHO Clinical Characterisation Protocol prospective multicentre observational cohort study. doi:10.1101/2020.12.19.20248559

DOI
10.1101/2020.12.19.20248559
Journal article

Establishment of CORONET; COVID-19 Risk in Oncology Evaluation Tool to identify cancer patients at low versus high risk of severe complications of COVID-19 infection upon presentation to hospital

Lee, R. J., Zhou, C., Wysocki, O., Shotton, R., Tivey, A., Lever, L., . . . Armstrong, A. C. (2020). Establishment of CORONET; COVID-19 Risk in Oncology Evaluation Tool to identify cancer patients at low versus high risk of severe complications of COVID-19 infection upon presentation to hospital. doi:10.1101/2020.11.30.20239095

DOI
10.1101/2020.11.30.20239095
Journal article

A systematic evaluation of IgM and IgG antibody assay accuracy in diagnosing acute Zika Virus infection in Brazil; lessons relevant to emerging infections

DOI
10.1101/2020.11.25.399386
Preprint

Outcomes of COVID-19 related hospitalization among people with HIV in the ISARIC WHO Clinical Characterization Protocol (UK): a prospective observational study.

Geretti, A. M., Stockdale, A. J., Kelly, S. H., Cevik, M., Collins, S., Waters, L., . . . Semple, M. G. (2020). Outcomes of COVID-19 related hospitalization among people with HIV in the ISARIC WHO Clinical Characterization Protocol (UK): a prospective observational study.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. doi:10.1093/cid/ciaa1605

DOI
10.1093/cid/ciaa1605
Journal article

Sequential infection with influenza A virus followed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to more severe disease and encephalitis in a mouse model of COVID-19

Clark, J. J., Penrice-Randal, R., Sharma, P., Kipar, A., Dong, X., Pennington, S. H., . . . Stewart, J. P. (2020). Sequential infection with influenza A virus followed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to more severe disease and encephalitis in a mouse model of COVID-19. doi:10.1101/2020.10.13.334532

DOI
10.1101/2020.10.13.334532
Journal article

Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon Antagonism

Moore, S. C., Penrice-Randal, R., Alruwaili, M., Randle, N., Armstrong, S., Hartley, C., . . . Hiscox, J. A. (2020). Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon Antagonism. Viruses, 12(10), 1164. doi:10.3390/v12101164

DOI
10.3390/v12101164
Journal article

MAJORA: Continuous integration supporting decentralised sequencing for SARS-CoV-2 genomic surveillance

DOI
10.1101/2020.10.06.328328
Preprint

Neurological disease in adults with Zika and chikungunya virus infection in Northeast Brazil: a prospective observational study

Brito Ferreira, M. L., Militão de Albuquerque, M. D. F. P., de Brito, C. A. A., de Oliveira França, R. F., Porto Moreira, Á. J., de Morais Machado, M. Í., . . . Solomon, T. (2020). Neurological disease in adults with Zika and chikungunya virus infection in Northeast Brazil: a prospective observational study. The Lancet Neurology, 19(10), 826-839. doi:10.1016/s1474-4422(20)30232-5

DOI
10.1016/s1474-4422(20)30232-5
Journal article

T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses

DOI
10.1101/2020.09.28.20202929
Preprint

Self-sampling of capillary blood for serological testing of SARS-CoV-2 by COVID-19 IgG ELISA

DOI
10.1101/2020.09.25.20183459
Preprint

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.

Knight, S. R., Ho, A., Pius, R., Buchan, I., Carson, G., Drake, T. M., . . . ISARIC4C investigators. (2020). Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.. BMJ: British Medical Journal, 370. doi:10.1136/bmj.m3339

DOI
10.1136/bmj.m3339
Journal article

1670O Prospective data of first 1,797 hospitalised patients with cancer and COVID-19 derived from the COVID-19 Clinical Information Network and international Severe Acute Respiratory and emerging Infections Consortium, WHO Coronavirus Clinical Characterisation Consortium

Palmieri, C., Turtle, L., Docherty, A., Harrison, E., Drake, T., Greenhalf, B., . . . Semple, M. G. (2020). 1670O Prospective data of first 1,797 hospitalised patients with cancer and COVID-19 derived from the COVID-19 Clinical Information Network and international Severe Acute Respiratory and emerging Infections Consortium, WHO Coronavirus Clinical Characterisation Consortium. In Annals of Oncology Vol. 31 (pp. S992). Elsevier BV. doi:10.1016/j.annonc.2020.08.1735

DOI
10.1016/j.annonc.2020.08.1735
Conference Paper

Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study

Swann, O., Holden, K., Turtle, L., Pollock, L., Fairfield, C., Drake, T., . . . ISARIC Coronavirus Clinical Characterisation Consortium (ISARIC4C) Investigators. (2020). Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study. BMJ, 370. doi:10.1136/bmj.m3249

DOI
10.1136/bmj.m3249
Journal article

Outcomes of COVID-19 related hospitalisation among people with HIV in the ISARIC WHO Clinical Characterisation Protocol UK Protocol: prospective observational study

Geretti, A. M., Stockdale, A. J., Kelly, S. H., Cevik, M., Collins, S., Waters, L., . . . Sullivan, A. (2020). Outcomes of COVID-19 related hospitalisation among people with HIV in the ISARIC WHO Clinical Characterisation Protocol UK Protocol: prospective observational study. doi:10.1101/2020.08.07.20170449

DOI
10.1101/2020.08.07.20170449
Journal article

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score

Knight, S. R., Ho, A., Pius, R., Buchan, I., Carson, G., Drake, T. M., . . . Harrison, E. M. (2020). Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score. doi:10.1101/2020.07.30.20165464

DOI
10.1101/2020.07.30.20165464
Journal article

Clinical characteristics of children and young people hospitalised with covid-19 in the United Kingdom: prospective multicentre observational cohort study

Swann, O. V., Holden, K., Turtle, L., Pollock, L., Fairfield, C. J., Drake, T. M., . . . Semple, M. G. (2020). Clinical characteristics of children and young people hospitalised with covid-19 in the United Kingdom: prospective multicentre observational cohort study. doi:10.1101/2020.07.14.20153320

DOI
10.1101/2020.07.14.20153320
Journal article

T cell immunity rather than antibody mediates cross-protection against Zika virus infection conferred by a live attenuated Japanese encephalitis SA14-14-2 vaccine.

Wang, R., Zhen, Z., Turtle, L., Hou, B., Li, Y., Wu, N., . . . An, J. (2020). T cell immunity rather than antibody mediates cross-protection against Zika virus infection conferred by a live attenuated Japanese encephalitis SA14-14-2 vaccine.. Applied microbiology and biotechnology. doi:10.1007/s00253-020-10710-z

DOI
10.1007/s00253-020-10710-z
Journal article

Antibody testing for COVID-19: A report from the National COVID Scientific Advisory Panel [version 1; peer review: 2 approved]

Adams, E. R., Ainsworth, M., Anand, R., Andersson, M. I., Auckland, K., Baillie, J. K., . . . Whitehouse, J. (2020). Antibody testing for COVID-19: A report from the National COVID Scientific Advisory Panel [version 1; peer review: 2 approved]. Wellcome Open Research, 5. doi:10.12688/wellcomeopenres.15927.1

DOI
10.12688/wellcomeopenres.15927.1
Journal article

Methods of inactivation of SARS-CoV-2 for downstream biological assays

Patterson, E. I., Prince, T., Anderson, E. R., Casas-Sanchez, A., Smith, S. L., Cansado-Utrilla, C., . . . Hughes, G. L. (2020). Methods of inactivation of SARS-CoV-2 for downstream biological assays. doi:10.1101/2020.05.21.108035

DOI
10.1101/2020.05.21.108035
Journal article

Rapid development of COVID-19 rapid diagnostics for low resource settings: accelerating delivery through transparency, responsiveness, and open collaboration

DOI
10.1101/2020.04.29.20082099
Preprint

Cross-Protection Against Zika Virus Infection Conferred by a Live Attenuated Japanese Encephalitis SA14-14-2 Vaccine

DOI
10.1101/2020.02.14.950352
Preprint

Outcomes of COVID-19 Related Hospitalisation Among People with HIV in the ISARIC WHO Clinical Characterisation Protocol UK Protocol: Prospective Observational Study

Geretti, A. M., Stockdale, A. J., Kelly, S. H., Cevik, M., Collins, S., Waters, L., . . . Group, C. H. A. S. E. S. (n.d.). Outcomes of COVID-19 Related Hospitalisation Among People with HIV in the ISARIC WHO Clinical Characterisation Protocol UK Protocol: Prospective Observational Study. SSRN Electronic Journal. doi:10.2139/ssrn.3666248

DOI
10.2139/ssrn.3666248
Journal article

2019

Adenovirus Type 7 causing severe lower respiratory tract infection in immunocompetent adults: a comparison of two contrasting cases from an intensive care unit in North West England

Wingfield, T., Dearden, L., Calvert, P., Osanlou, O., Johnston, B., Chawla, A., . . . Wenstone, R. (2019). Adenovirus Type 7 causing severe lower respiratory tract infection in immunocompetent adults: a comparison of two contrasting cases from an intensive care unit in North West England. Clinical Infection in Practice, 2, 100007. doi:10.1016/j.clinpr.2019.100007

DOI
10.1016/j.clinpr.2019.100007
Journal article

Low population Japanese encephalitis virus (JEV) seroprevalence in Udayapur district, Nepal, three years after a JE vaccination programme: a case for further catch up campaigns?

Turtle, L. C. W. (2019). Low population Japanese encephalitis virus (JEV) seroprevalence in Udayapur district, Nepal, three years after a JE vaccination programme: a case for further catch up campaigns?. PLoS Neglected Tropical Diseases, 13. doi:10.1371/journal.pntd.0007269

DOI
10.1371/journal.pntd.0007269
Journal article

Malawian Malaise

Turtle, L., & Kneen, R. (2019). Malawian Malaise. In Case Studies in Neurological Infections of Adults and Children (pp. 265-268). Cambridge University Press. doi:10.1017/9781139628839.062

DOI
10.1017/9781139628839.062
Chapter

Two Types of Shaking

Turtle and Gemma Buxton, L. (2019). Two Types of Shaking. In Case Studies in Neurological Infections of Adults and Children (pp. 255-259). Cambridge University Press. doi:10.1017/9781139628839.060

DOI
10.1017/9781139628839.060
Chapter

2018

The spectrum of neurological disease associated with Zika and chikungunya viruses in adults in Rio de Janeiro, Brazil: A case series

Mehta, R., Soares, C. N., Medialdea-Carrera, R., Ellul, M., Texeira da Silva, M. T., Rosala-Hallas, A., . . . Solomon, T. (2018). The spectrum of neurological disease associated with Zika and chikungunya viruses in adults in Rio de Janeiro, Brazil: A case series. PLoS Neglected Tropical Diseases, 12(2). doi:10.1371/journal.pntd.0006212

DOI
10.1371/journal.pntd.0006212
Journal article

2017

Haloprogin

Ramos-Martín, V., & Hope, W. (2017). Haloprogin. In Kucers the Use of Antibiotics A Clinical Review of Antibacterial Antifungal Antiparasitic and Antiviral Drugs Seventh Edition (pp. 2933-2935). doi:10.1201/9781315152110

DOI
10.1201/9781315152110
Chapter

2016

2015

An integrated model of care for neurological infections: the first six years of referrals to a specialist service at a university teaching hospital in Northwest England

Turtle, L., Jung, A., Beeching, N. J., Cocker, D., Davies, G. R., Nicolson, A., . . . Solomon, T. (2015). An integrated model of care for neurological infections: the first six years of referrals to a specialist service at a university teaching hospital in Northwest England. BMC INFECTIOUS DISEASES, 15. doi:10.1186/s12879-015-1109-3

DOI
10.1186/s12879-015-1109-3
Journal article

Correction: A Preliminary Randomized Double Blind Placebo-Controlled Trial of Intravenous Immunoglobulin for Japanese Encephalitis in Nepal

Rayamajhi, A., Nightingale, S., Bhatta, N. K., Singh, R., Ledger, E., Bista, K. P., . . . Solomon, T. (2015). Correction: A Preliminary Randomized Double Blind Placebo-Controlled Trial of Intravenous Immunoglobulin for Japanese Encephalitis in Nepal. PLOS ONE, 10(8), e0136008. doi:10.1371/journal.pone.0136008

DOI
10.1371/journal.pone.0136008
Journal article

A Preliminary Randomized Double Blind Placebo-Controlled Trial of Intravenous Immunoglobulin for Japanese Encephalitis in Nepal

Rayamajhi, A., Nightingale, S., Bhatta, N. K., Singh, R., Ledger, E., Bista, K. P., . . . Solomon, T. (2015). A Preliminary Randomized Double Blind Placebo-Controlled Trial of Intravenous Immunoglobulin for Japanese Encephalitis in Nepal. PLOS ONE, 10(4), e0122608. doi:10.1371/journal.pone.0122608

DOI
10.1371/journal.pone.0122608
Journal article

2014

What stops healthcare workers volunteering to fight Ebola in west Africa?

Solomon, T., Turtle, L., McGill, F., Matata, C., & Christley, R. (2014). What stops healthcare workers volunteering to fight Ebola in west Africa?. BMJ, 349(oct24 4), g6443. doi:10.1136/bmj.g6443

DOI
10.1136/bmj.g6443
Journal article

A case of iatrogenic adrenal suppression after co-administration of cobicistat and fluticasone nasal drops

Lewis, J., Turtle, L., Khoo, S., & Nsutebu, E. -N. (2014). A case of iatrogenic adrenal suppression after co-administration of cobicistat and fluticasone nasal drops. AIDS, 28(17), 2636-2637. doi:10.1097/qad.0000000000000462

DOI
10.1097/qad.0000000000000462
Journal article

Encephalitis, Viral

Turtle, L., & Solomon, T. (2014). Encephalitis, Viral. In Encyclopedia of the Neurological Sciences (pp. 20-24). Elsevier. doi:10.1016/b978-0-12-385157-4.00375-4

DOI
10.1016/b978-0-12-385157-4.00375-4
Chapter

Japanese encephalitis virus infection

Japanese encephalitis virus infection (2014). In Handbook of Clinical Neurology (pp. 561-576). Elsevier. doi:10.1016/b978-0-444-53488-0.00026-2

DOI
10.1016/b978-0-444-53488-0.00026-2
Chapter

2013

Innate Immune Mechanisms in Japanese Encephalitis Virus Infection: Effect on Transcription of Pattern Recognition Receptors in Mouse Neuronal Cells and Brain Tissue

Fadnis, P. R., Ravi, V., Desai, A., Turtle, L., & Solomon, T. (2013). Innate Immune Mechanisms in Japanese Encephalitis Virus Infection: Effect on Transcription of Pattern Recognition Receptors in Mouse Neuronal Cells and Brain Tissue. Viral Immunology, 26(6), 366-377. doi:10.1089/vim.2013.0016

DOI
10.1089/vim.2013.0016
Journal article

Japanese Encephalitis Virus Infection

Turtle, L., & Solomon, T. (2013). Japanese Encephalitis Virus Infection. In Viral Infections of the Human Nervous System (pp. 271-293). Springer Basel. doi:10.1007/978-3-0348-0425-7_11

DOI
10.1007/978-3-0348-0425-7_11
Chapter

2012

In routine UK hospital practice T-SPOT.TB™ is useful in some patients with a modest pre-test probability of active tuberculosis

Turtle, L., Kemp, T., Davies, G. R., Squire, S. B., Beeching, N. J., & Beadsworth, M. B. J. (2012). In routine UK hospital practice T-SPOT.TB™ is useful in some patients with a modest pre-test probability of active tuberculosis. European Journal of Internal Medicine, 23(4), 363-367. doi:10.1016/j.ejim.2012.01.002

DOI
10.1016/j.ejim.2012.01.002
Journal article

In routine UK hospital practice T-SPOT.TB™ is useful in some patients with a modest pre-test probability of active tuberculosis

Turtle, L., Kemp, T., Davies, G. R., Squire, S. B., Beeching, N. J., & Beadsworth, M. B. J. (2012). In routine UK hospital practice T-SPOT.TB™ is useful in some patients with a modest pre-test probability of active tuberculosis. European Journal of Internal Medicine, 23(4), 363-367. doi:10.1016/j.ejim.2012.01.002

DOI
10.1016/j.ejim.2012.01.002
Journal article

1636 Intravenous immunoglobulin to treat Japanese encephalitis; a randomised controlled trial in Nepalese children

Nightingale, S., Rayamajhi, A., Bhatta, N., Ledger, E., Griffiths, M., Turtle, L., . . . Solomon, T. (2012). 1636 Intravenous immunoglobulin to treat Japanese encephalitis; a randomised controlled trial in Nepalese children. In Journal of Neurology, Neurosurgery &amp; Psychiatry Vol. 83 (pp. e1.141-e1). BMJ. doi:10.1136/jnnp-2011-301993.24

DOI
10.1136/jnnp-2011-301993.24
Conference Paper

Encephalitis caused by flaviviruses

Turtle, L., Griffiths, M. J., & Solomon, T. (2012). Encephalitis caused by flaviviruses. QJM, 105(3), 219-223. doi:10.1093/qjmed/hcs013

DOI
10.1093/qjmed/hcs013
Journal article

Encephalitis caused by flaviviruses.

Turtle, L., Griffiths, M. J., & Solomon, T. (2012). Encephalitis caused by flaviviruses.. QJM., 105(3), 219-223. doi:10.1093/qjmed/hcs013

DOI
10.1093/qjmed/hcs013
Journal article

2011

Intensive Care Usage by HIV-Positive Patients in the HAART Era

Turtle, L., Vyakernam, R., Menon-Johansson, A., Nelson, M. R., & Soni, N. (2011). Intensive Care Usage by HIV-Positive Patients in the HAART Era. Interdisciplinary Perspectives on Infectious Diseases, 2011, 1-5. doi:10.1155/2011/847835

DOI
10.1155/2011/847835
Journal article

'Septrin psychosis' among renal transplant patients with Pneumocystis jirovecii pneumonia

Walker, L. E., Thomas, S., McBride, C., Howse, M., Turtle, L. C. W., Vivancos, R., . . . Beadsworth, M. B. J. (2011). 'Septrin psychosis' among renal transplant patients with Pneumocystis jirovecii pneumonia. Journal of Antimicrobial Chemotherapy, 66(5), 1117-1119. doi:10.1093/jac/dkr050

DOI
10.1093/jac/dkr050
Journal article

‘Septrin psychosis’ among renal transplant patients with Pneumocystis jirovecii pneumonia

Walker, L. E., Thomas, S., McBride, C., Howse, M., Turtle, L. C. W., Vivancos, R., . . . Beadsworth, M. B. J. (2011). ‘Septrin psychosis’ among renal transplant patients with Pneumocystis jirovecii pneumonia. Journal of Antimicrobial Chemotherapy, 66(5), 1117-1119. doi:10.1093/jac/dkr050

DOI
10.1093/jac/dkr050
Journal article

2009

An evaluation of the usefulness of neuroimaging for the diagnosis of Japanese encephalitis

Dung, N. M., Turtle, L., Chong, W. K., Mai, N. T., Thao, T. T., Thuy, T. T., . . . Solomon, T. (2009). An evaluation of the usefulness of neuroimaging for the diagnosis of Japanese encephalitis. Journal of Neurology, 256(12), 2052-2060. doi:10.1007/s00415-009-5249-5

DOI
10.1007/s00415-009-5249-5
Journal article

Severe pneumonia caused by ciprofloxacin resistant panton-valentine leukocidin producing community acquired meticillin resistant Staphylococcus aureus

Turtle, L., Wey, E., & James, E. (2009). Severe pneumonia caused by ciprofloxacin resistant panton-valentine leukocidin producing community acquired meticillin resistant Staphylococcus aureus. Journal of Infection, 58(1), 86-87. doi:10.1016/j.jinf.2008.10.008

DOI
10.1016/j.jinf.2008.10.008
Journal article

2008

Tics, twitches, tales: The experiences of Gilles de la Tourette's syndrome.

Turtle, L., & Robertson, M. M. (2008). Tics, twitches, tales: The experiences of Gilles de la Tourette's syndrome.. American Journal of Orthopsychiatry, 78(4), 449-455. doi:10.1037/a0014329

DOI
10.1037/a0014329
Journal article

2007

Medical emergencies in human immunodeficiency virus infected patients

Turtle, L. (2007). Medical emergencies in human immunodeficiency virus infected patients. Current Anaesthesia &amp; Critical Care, 18(2), 94-106. doi:10.1016/j.cacc.2007.03.004

DOI
10.1016/j.cacc.2007.03.004
Journal article

2003

Urocortin protects cardiac myocytes from ischemia/reperfusion injury by attenuating calcium insensitive phospholipase A <sub>2</sub> gene expression

Lawrence, K. M., Scarabelli, T. M., Turtle, L., Chanalaris, A., Townsend, P. A., Carroll, C. J., . . . Latchman, D. S. (2003). Urocortin protects cardiac myocytes from ischemia/reperfusion injury by attenuating calcium insensitive phospholipase A <sub>2</sub> gene expression. The FASEB Journal, 17(15), 2313-2315. doi:10.1096/fj.02-0832fje

DOI
10.1096/fj.02-0832fje
Journal article

Undated

T-Cell and Antibody Responses to First BNT162b2 Vaccine Dose in Previously SARS-CoV-2-Infected and Infection-Naive UK Healthcare Workers: A Multicentre, Prospective, Observational Cohort Study

Angyal, A., Longet, S., Moore, S., Payne, R. P., Harding, A., Tipton, T., . . . Group, P. I. T. C. H. C. (n.d.). T-Cell and Antibody Responses to First BNT162b2 Vaccine Dose in Previously SARS-CoV-2-Infected and Infection-Naive UK Healthcare Workers: A Multicentre, Prospective, Observational Cohort Study.

Journal article