About
I am currently a Senior lecturer at the Department of Pharmacology and Therapeutics where I lead the drug antigen discovery group with a focus on the identification of naturally processed and presented HLA ligands that could initiate an immune response. Comprehensive knowledge of antigenic peptides and their relationship with HLA proteins is crucial for designing innovative cancer immunotherapy and better diagnostic assays for drug hypersensitivity among other autoimmune diseases.
I completed my Ph D in medicinal chemistry at Liverpool University with a prestigious Pfizer funded studentship under the supervision of Prof Kevin Park and Dr Andrew Stachulski, in which I focused on the synthesis of reactive drug metabolites. I then took up a postdoctoral position in the NIHR Liverpool Biomedical Research Centre under the guidance of Prof Sir Munir Pirmohamed and Prof Kevin Park, followed by a Senior Postdoctoral Fellow at the MRC Centre for Drug Safety Science, where I developed mass spectrometric-based bioanalytical platforms for investigating drug metabolism and drug-protein interaction/adduct. This knowledge, combined with computational modelling, has allowed us to identify novel therapeutic targets and action mechanisms for drug design.