Research outputs
2026
Evaluation of detection performance and cost-effectiveness of IDEXX Colilert-18 and ChromAgar for environmental surveillance of extended-spectrum beta-lactamase <i>Escherichia coli</i> in water samples from urban marketplaces in Blantyre, Malawi
Masoamphambe, E. F., Chipinga, J., Mphasa, M., Chidziwitsano, K., Panulo, M., Jafali, J., . . . Cocker, D. (2026). Evaluation of detection performance and cost-effectiveness of IDEXX Colilert-18 and ChromAgar for environmental surveillance of extended-spectrum beta-lactamase <i>Escherichia coli</i> in water samples from urban marketplaces in Blantyre, Malawi. MICROBIOLOGY SPECTRUM, 14(7), CP3. doi:10.1128/spectrum.01695-25
The global Dx AMR collaborative: an approach to strengthen the role of diagnostics in combating antimicrobial resistance
Ferreyra, C., Awandare, G. A., Mpundu, M., & Cocker, D. (2026). The global Dx AMR collaborative: an approach to strengthen the role of diagnostics in combating antimicrobial resistance. Lancet Digital Health, 8(2). doi:10.1016/j.landig.2025.100951
Transmission of extended spectrum β-lactamase-producing Escherichia coli and antimicrobial resistance gene flow across One Health compartments in eastern Africa: a whole-genome sequence analysis from a prospective cohort study
Musicha, P., Beale, M. A., Cocker, D., Oruru, F. A., Zuza, A., Salifu, C., . . . Thomson, N. R. (2026). Transmission of extended spectrum β-lactamase-producing Escherichia coli and antimicrobial resistance gene flow across One Health compartments in eastern Africa: a whole-genome sequence analysis from a prospective cohort study. Lancet Microbe, 7(1). doi:10.1016/j.lanmic.2025.101224
2025
Environmental hazards from pollution of antibiotics and resistance-driving chemicals in an urban river network from Malawi.
Cocker, D., Mwapasa, T., Grabic, R., Grabicová, K., Staňová, A. V., Chidziwisano, K., . . . Singer, A. C. (2025). Environmental hazards from pollution of antibiotics and resistance-driving chemicals in an urban river network from Malawi.. npj antimicrobials and resistance, 3(1), 85. doi:10.1038/s44259-025-00149-5
Effect-based and (non-)target chemical analyses reveal concerning levels of emerging contaminants in urban streams in Sub-Saharan Africa
Mikušová, P., Toušová, Z., Smutná, M., Grabicová, K., Grabic, R., Singer, A. C., . . . Hilscherová, K. (2025). Effect-based and (non-)target chemical analyses reveal concerning levels of emerging contaminants in urban streams in Sub-Saharan Africa. Journal of Hazardous Materials, 497. doi:10.1016/j.jhazmat.2025.139654
Environmental hazards from pollution of antibiotics and resistance-driving chemicals in urban river networks of Malawi
Evaluating Colilert and ChromAgar methods for the detection of ESBL bacteria in water samples from urban markets in Blantyre, Malawi
Masoamphambe, E., Cocker, D., Feasey, N., Chidziwitsano, K., Panulo, M., Berendes, D., . . . Morse, T. (2025). Evaluating Colilert and ChromAgar methods for the detection of ESBL bacteria in water samples from urban markets in Blantyre, Malawi. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 152, 2 pages. doi:10.1016/j.ijid.2024.107580
High prevelance and concentrations of antibiotics identified within urban river networks of Southern Malawi
Cocker, D., Mwapasa, T., Grabic, R., Grabicová, K., Staňová, A. V., Chidziwisano, K., . . . Singer, A. (2025). High prevelance and concentrations of antibiotics identified within urban river networks of Southern Malawi. International Journal of Infectious Diseases, 152, 107614. doi:10.1016/j.ijid.2024.107614
Risk Perception and Psychosocial Factors Influencing Exposure to Antimicrobial Resistance through Environmental Pathways in Malawi
Chidziwisano, K., Cocker, D., Kumwenda, T. M., Amos, S., Feasey, N., & Morse, T. (2025). Risk Perception and Psychosocial Factors Influencing Exposure to Antimicrobial Resistance through Environmental Pathways in Malawi. American Journal of Tropical Medicine and Hygiene, 112(2), 355-363. doi:10.4269/ajtmh.24-0253
Transmission dynamics for invasive Non-Typhoidal S almonella serovars (TiNTS): protocol for a household study of transmission and immune response to non-typhoidal Salmonella in Malawi
Johnston, P. I., Chizani, K., Chirwa, E., Dale, H., Patel, P., Silungwe, N., . . . Nyirenda, T. (2025). Transmission dynamics for invasive Non-Typhoidal S almonella serovars (TiNTS): protocol for a household study of transmission and immune response to non-typhoidal Salmonella in Malawi. Wellcome Open Research, 10. doi:10.12688/wellcomeopenres.24663.1
2024
Addressing Antimicrobial Resistance with Digital Approaches 1 Using digital health technologies to optimise antimicrobial use globally
Rawson, T. M., Zhu, N., Galiwango, R., Cocker, D., Islam, M. S., Myall, A., . . . Holmes, A. H. (2024). Addressing Antimicrobial Resistance with Digital Approaches 1 Using digital health technologies to optimise antimicrobial use globally. LANCET DIGITAL HEALTH, 6(12), e914-e925. doi:10.1016/S2589-7500(24)00198-5
Time to define One Health approaches to tackling antimicrobial resistance
Musicha, P., Morse, T., Cocker, D., Mugisha, L., Jewell, C. P., & Feasey, N. A. (2024). Time to define One Health approaches to tackling antimicrobial resistance. NATURE COMMUNICATIONS, 15(1), 3 pages. doi:10.1038/s41467-024-53057-z
Healthcare as a driver, reservoir and amplifier of antimicrobial resistance: opportunities for interventions
Cocker, D., Birgand, G., Zhu, N., Rodriguez-Manzano, J., Ahmad, R., Jambo, K., . . . Holmes, A. (2024). Healthcare as a driver, reservoir and amplifier of antimicrobial resistance: opportunities for interventions. NATURE REVIEWS MICROBIOLOGY, 22(10), 636-649. doi:10.1038/s41579-024-01076-4
Key environmental exposure pathways to antimicrobial resistant bacteria in southern Malawi: A SaniPath approach
Mwapasa, T., Chidziwisano, K., Mphasa, M., Cocker, D., Rimella, L., Amos, S., . . . Morse, T. (2024). Key environmental exposure pathways to antimicrobial resistant bacteria in southern Malawi: A SaniPath approach. SCIENCE OF THE TOTAL ENVIRONMENT, 945, 10 pages. doi:10.1016/j.scitotenv.2024.174142
Protecting healthcare and patient pathways from infection and antimicrobial resistance
Cocker, D., Fitzgerald, R., Brown, C. S., & Holmes, A. (2024). Protecting healthcare and patient pathways from infection and antimicrobial resistance. BMJ, 387. doi:10.1136/bmj-2023-077927
2023
Inference on extended-spectrum beta-lactamase Escherichia coli and Klebsiella pneumoniae data through SMC<SUP>2</SUP>
Rimella, L., Alderton, S., Sammarro, M., Rowlingson, B., Cocker, D., Feasey, N., . . . Jewell, C. (2023). Inference on extended-spectrum beta-lactamase Escherichia coli and Klebsiella pneumoniae data through SMC<SUP>2</SUP>. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS, 72(5), 1435-1451. doi:10.1093/jrsssc/qlad055
Mortality associated with third-generation cephalosporin resistance in Enterobacterales bloodstream infections at eight sub-Saharan African hospitals (MBIRA): a prospective cohort study.
Aiken, A. M., Rehman, A. M., de Kraker, M. E. A., Madrid, L., Kebede, M., Labi, A. -K., . . . MBIRA study collaborators. (2023). Mortality associated with third-generation cephalosporin resistance in Enterobacterales bloodstream infections at eight sub-Saharan African hospitals (MBIRA): a prospective cohort study.. The Lancet. Infectious diseases, S1473-3099(23)00233-5. doi:10.1016/s1473-3099(23)00233-5
Investigating One Health risks for human colonisation with extended spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Malawian households: a longitudinal cohort study.
Cocker, D., Chidziwisano, K., Mphasa, M., Mwapasa, T., Lewis, J. M., Rowlingson, B., . . . Feasey, N. A. (2023). Investigating One Health risks for human colonisation with extended spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Malawian households: a longitudinal cohort study.. The Lancet. Microbe, S2666-5247(23)00062-9. doi:10.1016/s2666-5247(23)00062-9
Clinical features and management of individuals admitted to hospital with monkeypox and associated complications acrossthe UK: a retrospective cohort study
Fink, D. L., Callaby, H., Luintel, A., Beynon, W., Bond, H., Lim, E. Y., . . . Dunning, J. (2023). Clinical features and management of individuals admitted to hospital with monkeypox and associated complications acrossthe UK: a retrospective cohort study. LANCET INFECTIOUS DISEASES, 23(5), 589-597. doi:10.1016/S1473-3099(22)00806-4
Risk Factors, Temporal Dependence, and Seasonality of Human extended-spectrum beta-lactamases-producing Escherichia coli and Klebsiella pneumoniae Colonization in Malawi: A Longitudinal Model-based Approach
Sammarro, M., Rowlingson, B., Cocker, D., Chidziwisano, K., Jacob, S. T., Kajumbula, H., . . . Jewell, C. (2023). Risk Factors, Temporal Dependence, and Seasonality of Human extended-spectrum beta-lactamases-producing Escherichia coli and Klebsiella pneumoniae Colonization in Malawi: A Longitudinal Model-based Approach. CLINICAL INFECTIOUS DISEASES, 77(1), 1-8. doi:10.1093/cid/ciad117
Circumstances for treatment and control of invasive Enterobacterales infections in eight hospitals across sub-Saharan Africa: a cross-sectional study
Aiken, A. M., Nyamwaya, B., Madrid, L., Edessa, D., Labi, A. K., Obeng-Nkrumah, N., . . . Whitelaw, A. (2023). Circumstances for treatment and control of invasive Enterobacterales infections in eight hospitals across sub-Saharan Africa: a cross-sectional study. Gates Open Research, 7. doi:10.12688/gatesopenres.14267.1
Drivers of Resistance in Uganda and Malawi (DRUM): a protocol for the evaluation of One-Health drivers of Extended Spectrum Beta Lactamase (ESBL) resistance in Low-Middle Income Countries (LMICs)
Cocker, D., Sammarro, M., Chidziwisano, K., Elviss, N., Jacob, S. T., Kajumbula, H., . . . Feasey, N. A. (2023). Drivers of Resistance in Uganda and Malawi (DRUM): a protocol for the evaluation of One-Health drivers of Extended Spectrum Beta Lactamase (ESBL) resistance in Low-Middle Income Countries (LMICs). Wellcome Open Research, 7. doi:10.12688/wellcomeopenres.17581.2
2022
A novel, magnetic bead-based extraction method for the isolation of antimicrobial resistance genes with a case study in river water in Malawi
Byrne, R. L., Cocker, D., Alyayyoussi, G., Mphasa, M., Charles, M., Mandula, T., . . . Edwards, T. (2022). A novel, magnetic bead-based extraction method for the isolation of antimicrobial resistance genes with a case study in river water in Malawi. JOURNAL OF APPLIED MICROBIOLOGY, 133(5), 3191-3200. doi:10.1111/jam.15755
Treatment and control of invasive Gram-negative bacterial infection in eight hospitals across sub-Saharan Africa: a cross-sectional study
Inference on Extended-Spectrum Beta-Lactamase Escherichia coli and Klebsiella pneumoniae data through SMC$^2$
Risk factors, temporal dependence, and seasonality of human ESBL-producing <i>E. coli</i> and <i>K. pneumoniae</i> colonisation in Malawi: a longitudinal model-based approach
Treatment and control of invasive Gram-negative bacterial infection in eight hospitals across sub-Saharan Africa: a cross-sectional study
Drivers of Resistance in Uganda and Malawi (DRUM): a protocol for the evaluation of One-Health drivers of Extended Spectrum Beta Lactamase (ESBL) resistance in Low-Middle Income Countries (LMICs)
2021
HIGH LEVELS OF EXTENDED SPECTRUM BETA-LACTAMASE (ESBL) CONTAMINATION ARE FOUND IN MALAWIAN HOUSEHOLDS WITH BASIC WATER, SANITATION AND HYGIENE (WASH) ACCESS
Cocker, D., Chidziwisano, K., Elviss, N., Singer, A. C., Morse, T., & Feasey, N. (2021). HIGH LEVELS OF EXTENDED SPECTRUM BETA-LACTAMASE (ESBL) CONTAMINATION ARE FOUND IN MALAWIAN HOUSEHOLDS WITH BASIC WATER, SANITATION AND HYGIENE (WASH) ACCESS. In AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Vol. 105 (pp. 276). Retrieved from https://www.webofscience.com/
Lessons learnt from the rapid implementation of reusable personal protective equipment for COVID-19 in Malawi
Limani, F., Garley, D., Cocker, D., Patel, P., Patel, P., Gordon, S., . . . Freyne, B. (2021). Lessons learnt from the rapid implementation of reusable personal protective equipment for COVID-19 in Malawi. BMJ GLOBAL HEALTH, 6(9), 6 pages. doi:10.1136/bmjgh-2021-006498
A novel magnetic bead-based extraction method for the isolation of antimicrobial resistance genes with a case study in river water in Malawi
2020
First case report of a successfully managed severe COVID-19 infection in Malawi
Banda, N. P., Hara, W., Cocker, D., Musasa, S., Burke, R. M., Brown, C., . . . Morton, B. (2020). First case report of a successfully managed severe COVID-19 infection in Malawi. MALAWI MEDICAL JOURNAL, 32(4), 124-126. doi:10.4314/mmj.v32i4.8
First case report of a successfully managed severe COVID-19 infection in Malawi
Banda, N. P., Hara, W., Cocker, D., Musasa, S., Burke, R. M., Brown, C., . . . Morton, B. (2020). First case report of a successfully managed severe COVID-19 infection in Malawi. Malawi Medical Journal the Journal of Medical Association of Malawi, 32(4), 226-228. doi:10.4314/mmj.v32i4.8
2019
Linezolid for drug-resistant pulmonary tuberculosis
Singh, B., Cocker, D., Ryan, H., & Sloan, D. J. (2019). Linezolid for drug-resistant pulmonary tuberculosis. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (3), 85 pages. doi:10.1002/14651858.CD012836.pub2
2017
Linezolid for drug-resistant tuberculosis
Singh, B., Cocker, D., Ryan, H., & Sloan, D. J. (2017). Linezolid for drug-resistant tuberculosis. Cochrane Database of Systematic Reviews, 2017(11). doi:10.1002/14651858.CD012836
2016
Initial Accuracy of HIV Rapid Test Kits Stored in Suboptimal Conditions and Validity of Delayed Reading of Oral Fluid Tests
Choko, A. T., Taegtmeyer, M., MacPherson, P., Cocker, D., Khundi, M., Thindwa, D., . . . Corbett, E. L. (2016). Initial Accuracy of HIV Rapid Test Kits Stored in Suboptimal Conditions and Validity of Delayed Reading of Oral Fluid Tests. PLOS ONE, 11(6), 8 pages. doi:10.1371/journal.pone.0158107
Clinical and scientific letters: On-going lessons in fluid prescription: assessment of adherence to weight-based intravenous fluid prescribing in medical inpatients (vol 15, pg 503, 2015)
Cocker, D., Sloan, D., Carlin, F., Marks, E., & Beadsworth, M. (2016). Clinical and scientific letters: On-going lessons in fluid prescription: assessment of adherence to weight-based intravenous fluid prescribing in medical inpatients (vol 15, pg 503, 2015). CLINICAL MEDICINE, 16(1), 61. doi:10.7861/clinmedicine.16-1-61b
2015
Fatal oxidative haemolysis and methaemoglobinaemia in a patient with alkaptonuria and acute kidney injury
Mullan, A., Cocker, D., Taylor, G., Millar, C., & Ranganath, L. (2015). Fatal oxidative haemolysis and methaemoglobinaemia in a patient with alkaptonuria and acute kidney injury. CLINICAL KIDNEY JOURNAL, 8(1), 109-112. doi:10.1093/ckj/sfu121
On-going lessons in fluid prescription: assessment of adherence to weight-based intravenous fluid prescribing in medical inpatients
Cocker, D., Sloane, D., Carlin, F., Marks, E., & Beadsworth, M. (2015). On-going lessons in fluid prescription: assessment of adherence to weight-based intravenous fluid prescribing in medical inpatients. CLINICAL MEDICINE, 15(5), 503-504. doi:10.7861/clinmedicine.15-5-503
Fahr's disease: a rare neurological presentation in a tropical setting
Otu, A. A., Anikwe, J. C., & Cocker, D. (2015). Fahr's disease: a rare neurological presentation in a tropical setting. CLINICAL CASE REPORTS, 3(10), 806-808. doi:10.1002/ccr3.349
An integrated model of care for neurological infections: the first six years of referrals to a specialist service at a university teaching hospital in Northwest England
Turtle, L., Jung, A., Beeching, N. J., Cocker, D., Davies, G. R., Nicolson, A., . . . Solomon, T. (2015). An integrated model of care for neurological infections: the first six years of referrals to a specialist service at a university teaching hospital in Northwest England. BMC INFECTIOUS DISEASES, 15. doi:10.1186/s12879-015-1109-3
2014
Lemierre's disease: a case with bilateral iliopsoas abscesses and a literature review
Bird, N. T. E., Cocker, D., Cullis, P., Schofield, R., Challoner, B., Hayes, A., & Brett, M. (2014). Lemierre's disease: a case with bilateral iliopsoas abscesses and a literature review. WORLD JOURNAL OF EMERGENCY SURGERY, 9, 7 pages. doi:10.1186/1749-7922-9-38