2022
Atherton, P., Konstantinou, R., Neo, S. P., Wang, E., Balloi, E., Ptushkina, M., . . . Ballestrem, C. (2022). Tensin3 interaction with talin drives the formation of fibronectin-associated fibrillar adhesions. JOURNAL OF CELL BIOLOGY, 221(10). doi:10.1083/jcb.202107022DOI: 10.1083/jcb.202107022
2021
London, J. A., Wang, E. C. S., Barsukov, I. L., Yates, E. A., & Stachulski, A. V. (2021). Synthesis and toxicity profile in 293 human embryonic kidney cells of the beta D-glucuronide derivatives of ortho-, meta- and para-cresol. CARBOHYDRATE RESEARCH, 499. doi:10.1016/j.carres.2020.108225DOI: 10.1016/j.carres.2020.108225
2020
Du, M., Wang, G., Barsukov, I. L., Gross, S. R., Smith, R., & Rudland, P. S. (2020). Direct interaction of metastasis-inducing S100P protein with tubulin causes enhanced cell migration without changes in cell adhesion. BIOCHEMICAL JOURNAL, 477(6), 1159-1178. doi:10.1042/BCJ20190644DOI: 10.1042/BCJ20190644
Atherton, P., Lausecker, F., Carisey, A., Gilmore, A., Critchley, D., Barsukov, I., & Ballestrem, C. (2020). Relief of talin autoinhibition triggers a force-independent association with vinculin. JOURNAL OF CELL BIOLOGY, 219(1). doi:10.1083/jcb.201903134DOI: 10.1083/jcb.201903134
SHANK3 in oncogenic RAS signaling. (Conference Paper)
Lilja, J., Jcaquement, G., Posada, I. M. D., Laasola, P., Vesilahti, E. -M., Miihkinen, M., . . . Ivaska, J. (2020). SHANK3 in oncogenic RAS signaling.. In MOLECULAR CANCER RESEARCH Vol. 18 (pp. 67). Retrieved from https://www.webofscience.com/
2019
A further unique chondroitin sulfate from the shrimp Litopenaeus vannamei with antithrombin activity that modulates acute inflammation (Journal article)
Palhares, L. C. G. F., Brito, A. S., de Lima, M. A., Nader, H. B., London, J. A., Barsukov, I. L., . . . Chavante, S. F. (2019). A further unique chondroitin sulfate from the shrimp Litopenaeus vannamei with antithrombin activity that modulates acute inflammation. CARBOHYDRATE POLYMERS, 222. doi:10.1016/j.carbpol.2019.115031DOI: 10.1016/j.carbpol.2019.115031
2018
Byrne, D. P., Li, Y., Ramakrishnan, K., Barsukov, I. L., Yates, E. A., Eyers, C. E., . . . Eyers, P. A. (2018). New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors. BIOCHEMICAL JOURNAL, 475(15), 2417-2433. doi:10.1042/BCJ20180265DOI: 10.1042/BCJ20180265
Co-ordination of mechanotransduction by talin and vinculin (Conference Paper)
Atherton, P., Lausecker, F., Barsukov, I., Critchley, D., & Ballestrem, C. (2018). Co-ordination of mechanotransduction by talin and vinculin. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 99 (pp. A21). Retrieved from https://www.webofscience.com/
2017
Baxter, N. J., Zacharchenko, T., Barsukov, I. L., & Williamson, M. P. (2017). Pressure-Dependent Chemical Shifts in the R3 Domain of Talin Show that It Is Thermodynamically Poised for Binding to Either Vinculin or RIAM. Structure, 25(12), 1856-1866.e2. doi:10.1016/j.str.2017.10.008DOI: 10.1016/j.str.2017.10.008
Almeida, T. B., Carnell, A. J., Barsukov, I. L., & Berry, N. G. (2017). Targeting SxIP-EB1 interaction: An integrated approach to the discovery of small molecule modulators of dynamic binding sites. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-15502-6DOI: 10.1038/s41598-017-15502-6
Lilja, J., Zacharchenko, T., Georgiadou, M., Jacquemet, G., Franceschi, N. D., Peuhu, E., . . . Ivaska, J. (2017). SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras. Nature Cell Biology, 19(4), 292-305. doi:10.1038/ncb3487DOI: 10.1038/ncb3487
2016
Biophysical Analysis of the N-Terminal Domain from the Human Protein Phosphatase 1 Nuclear Targeting Subunit PNUTS Suggests an Extended Transcription Factor TFIIS-Like Fold (Journal article)
Zacharchenko, T., Barsukov, I., Rigden, D. J., Bennett, D., & Mayans, O. (2016). Biophysical Analysis of the N-Terminal Domain from the Human Protein Phosphatase 1 Nuclear Targeting Subunit PNUTS Suggests an Extended Transcription Factor TFIIS-Like Fold. Protein Journal, 35(5), 240-345. doi:10.1007/s10930-016-9677-7DOI: 10.1007/s10930-016-9677-7
Zhou, T., Fleming, J. R., Franke, B., Bogomolovas, J., Barsukov, I., Rigden, D. J., . . . Mayans, O. (2016). CARP interacts with titin at a unique helical N2A sequence and at the domain Ig81 to form a structured complex. FEBS LETTERS, 590(18), 3098-3110. doi:10.1002/1873-3468.12362DOI: 10.1002/1873-3468.12362
LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex (Journal article)
Zacharchenko, T., Qian, X., Goult, B. T., Jethwa, D., Almeida, T. B., Ballestrem, C., . . . Barsukov, I. L. (2016). LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex. Structure, 24(7), 1130-1141. doi:10.1016/j.str.2016.04.016DOI: 10.1016/j.str.2016.04.016
SHANK3 Structure Reveals a RAS-associated Domain Regulating Integrin Activation. (Conference Paper)
Lilja, J., Zacharchenko, T., Georgiadou, M., Kreienkamp, H., Barsukov, I., & Ivaska, J. (2016). SHANK3 Structure Reveals a RAS-associated Domain Regulating Integrin Activation.. In MOLECULAR BIOLOGY OF THE CELL Vol. 27. Retrieved from https://www.webofscience.com/
SHANK3 Structure Reveals a RAS-associated Domain Regulating Integrin Activation. (Conference Paper)
Lilja, J., Zacharchenko, T., Georgiadou, M., Kreienkamp, H., Barsukov, I., & Ivaska, J. (2016). SHANK3 Structure Reveals a RAS-associated Domain Regulating Integrin Activation.. In MOLECULAR BIOLOGY OF THE CELL Vol. 27. Retrieved from https://www.webofscience.com/
2015
Vinculin controls talin engagement with the actomyosin machinery. (Journal article)
Atherton, P., Stutchbury, B., Wang, D. -Y., Jethwa, D., Tsang, R., Meiler-Rodriguez, E., . . . Ballestrem, C. (2015). Vinculin controls talin engagement with the actomyosin machinery.. Nature communications, 6. doi:10.1038/ncomms10038DOI: 10.1038/ncomms10038
Parallel evolution or purifying selection, not introgression, explains similarity in the pyrethroid detoxification linked GSTE4 of Anopheles gambiae and An. arabiensis (Journal article)
Wilding, C. S., Weetman, D., Rippon, E. J., Steen, K., Mawejje, H. D., Barsukov, I., & Donnelly, M. J. (2015). Parallel evolution or purifying selection, not introgression, explains similarity in the pyrethroid detoxification linked GSTE4 of Anopheles gambiae and An. arabiensis. MOLECULAR GENETICS AND GENOMICS, 290(1), 201-215. doi:10.1007/s00438-014-0910-9DOI: 10.1007/s00438-014-0910-9
2014
S100A4 regulates the Src-tyrosine kinase dependent differentiation of Th17 cells in rheumatoid arthritis (Journal article)
Brisslert, M., Bian, L., Svensson, M. N. D., Santos, R. F., Jonsson, I. -M., Barsukov, I., . . . Bokarewa, M. I. (2014). S100A4 regulates the Src-tyrosine kinase dependent differentiation of Th17 cells in rheumatoid arthritis. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1842(11), 2049-2059. doi:10.1016/j.bbadis.2014.07.003DOI: 10.1016/j.bbadis.2014.07.003
S100A4 REGULATES THE SRC-THYROSINE KINASE DEPENDENT DIFFERENTIATION OF TH17 CELLS IN RHEUMATOID ARTHRITIS (Conference Paper)
Brisslert, M., Bian, L., Svensson, M., Santos, R., Jonsson, I. -M., Erlandsson, M., . . . Bokarewa, M. (2014). S100A4 REGULATES THE SRC-THYROSINE KINASE DEPENDENT DIFFERENTIATION OF TH17 CELLS IN RHEUMATOID ARTHRITIS. In ANNALS OF THE RHEUMATIC DISEASES Vol. 73 (pp. 129). doi:10.1136/annrheumdis-2014-eular.5414DOI: 10.1136/annrheumdis-2014-eular.5414
2013
SHANK3 Gene Mutations Associated with Autism Facilitate Ligand Binding to the Shank3 Ankyrin Repeat Region (Journal article)
Mameza, M. G., Dvoretskova, E., Bamann, M., Hoenck, H. -H., Gueler, T., Boeckers, T. M., . . . Kreienkamp, H. -J. (2013). SHANK3 Gene Mutations Associated with Autism Facilitate Ligand Binding to the Shank3 Ankyrin Repeat Region. JOURNAL OF BIOLOGICAL CHEMISTRY, 288(37), 26697-26708. doi:10.1074/jbc.M112.424747DOI: 10.1074/jbc.M112.424747
Deubiquitylases From Genes to Organism (Journal article)
Clague, M. J., Barsukov, I., Coulson, J. M., Liu, H., Rigden, D. J., & Urbé, S. (2013). Deubiquitylases From Genes to Organism. Physiological Reviews, 93(3), 1289-1315. doi:10.1152/physrev.00002.2013DOI: 10.1152/physrev.00002.2013
'RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover' (Journal article)
Goult, B. T., Zacharchenko, T., Bate, N., Tsang, R., Hey, F., Gingras, A. R., . . . Barsukov, I. L. (2013). 'RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover'. Journal of Biological Chemistry, 288(12), 8238-8249.
'Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: Implications for talin activation' (Journal article)
Goult, B. T., Xu, X. P., Gingras, A. R., Swift, M., Patel, B., Bate, N., . . . Hanein, D. (2013). 'Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: Implications for talin activation'. Journal of Structural Biology.
2012
The intracellular Ig fold: a robust protein scaffold for the engineering of molecular recognition (Journal article)
Bruning, M., Barsukov, I., Franke, B., Barbieri, S., Volk, M., Leopoldseder, S., . . . Mayans, O. (2012). The intracellular Ig fold: a robust protein scaffold for the engineering of molecular recognition. Protein Engineering Design and Selection, 25(5), 205-212. doi:10.1093/protein/gzs007DOI: 10.1093/protein/gzs007
Asymmetric Mode of Ca2+-S100A4 Interaction with Nonmuscle Myosin IIA Generates Nanomolar Affinity Required for Filament Remodeling (Journal article)
Elliott, P. R., Irvine, A. F., Jung, H. S., Tozawa, K., Pastok, M. W., Picone, R., . . . Barsukov, I. L. (2012). Asymmetric Mode of Ca2+-S100A4 Interaction with Nonmuscle Myosin IIA Generates Nanomolar Affinity Required for Filament Remodeling. STRUCTURE, 20(4), 654-666. doi:10.1016/j.str.2012.02.002DOI: 10.1016/j.str.2012.02.002
2011
Structural variability of the ubiquitin specific protease DUSP-UBL double domains (Journal article)
Elliott, P. R., Liu, H., Pastok, M. W., Grossmann, G. J., Rigden, D. J., Clague, M. J., . . . Barsukov, I. L. (2011). Structural variability of the ubiquitin specific protease DUSP-UBL double domains. FEBS LETTERS, 585(21), 3385-3390. doi:10.1016/j.febslet.2011.09.040DOI: 10.1016/j.febslet.2011.09.040
A study of the membrane association and regulatory effect of the phospholemman cytoplasmic domain (Journal article)
Hughes, E., Whittaker, C. A. P., Barsukov, I. L., Esmann, M., & Middleton, D. A. (2011). A study of the membrane association and regulatory effect of the phospholemman cytoplasmic domain. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1808(4), 1021-1031. doi:10.1016/j.bbamem.2010.11.024DOI: 10.1016/j.bbamem.2010.11.024
Mechanism of the Ca²+-dependent interaction between S100A4 and tail fragments of nonmuscle myosin heavy chain IIA (Journal article)
Badyal, S. K., Basran, J., Bhanji, N., Kim, J. H., Chavda, A. P., Jung, H. S., . . . Bagshaw, C. R. (2011). Mechanism of the Ca²+-dependent interaction between S100A4 and tail fragments of nonmuscle myosin heavy chain IIA. J Mol Biol, 405, 1004-1026.
Resonance Assignments (Chapter)
Lian, L. Y., & Barsukov, I. L. (2011). Resonance Assignments. In L. -Y. Lian, & G. Roberts (Eds.), Protein NMR Spectros (pp. 55-82). Chichester: Willey.
2010
The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain (Journal article)
Elliott, P. R., Goult, B. T., Kopp, P. M., Bate, N., Grossmann, J. G., Roberts, G. C. K., . . . Barsukov, I. L. (2010). The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain. Structure, 18(10), 1289-1299. doi:10.1016/j.str.2010.07.011DOI: 10.1016/j.str.2010.07.011
Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation (Journal article)
Goult, B. T., Bouaouina, M., Elliott, P. R., Bate, N., Patel, B., Gingras, A. R., . . . Barsukov, I. L. (2010). Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation. The EMBO Journal, 29(6), 1069-1080. doi:10.1038/emboj.2010.4DOI: 10.1038/emboj.2010.4
Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin (Journal article)
Gingras, A. R., Bate, N., Goult, B. T., Patel, B., Kopp, P. M., Emsley, J., . . . Critchley, D. R. (2010). Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin. J Biol Chem, 285, 29577-29587.
Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation (Journal article)
Goult, B. J., Bouaouina, M., Elliott, P. R., Bate, N., Patel, B., Gingras, A. R., . . . Barsukov, I. L. (2010). Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation. EMBO Journal, 29(6), 1069-1080.
2009
The Structure of the N-Terminus of Kindlin-1: A Domain Important for αIIbβ3 Integrin Activation (Journal article)
Goult, B. T., Bouaouina, M., Harburger, D. S., Bate, N., Patel, B., Anthis, N. J., . . . Critchley, D. R. (2009). The Structure of the N-Terminus of Kindlin-1: A Domain Important for αIIbβ3 Integrin Activation. Journal of Molecular Biology, 394(5), 944-956. doi:10.1016/j.jmb.2009.09.061DOI: 10.1016/j.jmb.2009.09.061
The Structure of an Interdomain Complex That Regulates Talin Activity (Journal article)
Goult, B. T., Bate, N., Anthis, N. J., Wegener, K. L., Gingras, A. R., Patel, B., . . . Critchley, D. R. (2009). The Structure of an Interdomain Complex That Regulates Talin Activity. Journal of Biological Chemistry, 284(22), 15097-15106. doi:10.1074/jbc.m900078200DOI: 10.1074/jbc.m900078200
'Domain motion in cytochrome P450 reductase' (Journal article)
Ellis, J., Gutierrez, A., Barsukov, I. L., Huang, W. C., Grossmann, J. G., & Roberts, G. C. K. (2009). 'Domain motion in cytochrome P450 reductase'. The Journal of Biological Chemistry, 284(52), 36628-36637.
'Structural determinants of integrin binding to the talin rod' (Journal article)
Gingras, A. R., Ziegler, W. H., Bobkov, A. A., Joyce, M. G., Fasci, D., Himmel, M., . . . Critchley, D. R. (2009). 'Structural determinants of integrin binding to the talin rod'. The journal of Biological Chemistry, 284(13), 8866-8876.
Structural determinants of integrin binding to the talin rod. (Journal article)
Gingras, A. R., Ziegler, W. H., Bobkov, A. A., Joyce, M. G., Fasci, D., Himmel, M., . . . Critchley, D. R. (2009). Structural determinants of integrin binding to the talin rod.. J Biol Chem, 284(13), 8866-8876.
2008
Structural Basis for the Interaction between the Cytoplasmic Domain of the Hyaluronate Receptor Layilin and the Talin F3 Subdomain (Journal article)
Wegener, K. L., Basran, J., Bagshaw, C. R., Campbell, I. D., Roberts, G. C. K., Critchley, D. R., & Barsukov, I. L. (2008). Structural Basis for the Interaction between the Cytoplasmic Domain of the Hyaluronate Receptor Layilin and the Talin F3 Subdomain. Journal of Molecular Biology, 382(1), 112-126. doi:10.1016/j.jmb.2008.06.087DOI: 10.1016/j.jmb.2008.06.087
NMR assignment of the C-terminal actin-binding domain of talin (Journal article)
Goult, B. T., Gingras, A. R., Bate, N., Roberts, G. C. K., Critchley, D. R., & Barsukov, I. L. (2008). NMR assignment of the C-terminal actin-binding domain of talin. Biomolecular NMR Assignments, 2(1), 17-19. doi:10.1007/s12104-007-9073-5DOI: 10.1007/s12104-007-9073-5
Crystal structure of the Ca<sup>2+</sup>-form and Ca<sup>2+</sup>-binding kinetics of metastasis-associated protein, S100A4 (Journal article)
Gingras, A. R., Basran, J., Prescott, A., Kriajevska, M., Bagshaw, C. R., & Barsukov, I. L. (2008). Crystal structure of the Ca<sup>2+</sup>-form and Ca<sup>2+</sup>-binding kinetics of metastasis-associated protein, S100A4. FEBS Letters, 582(12), 1651-1656. doi:10.1016/j.febslet.2008.04.017DOI: 10.1016/j.febslet.2008.04.017
The structure of the C-terminal actin-binding domain of talin (Journal article)
Gingras, A. R., Bate, N., Goult, B. T., Hazelwood, L., Canestrelli, I., Grossmann, J. G., . . . Critchley, D. R. (2008). The structure of the C-terminal actin-binding domain of talin. The EMBO Journal, 27(2), 458-469. doi:10.1038/sj.emboj.7601965DOI: 10.1038/sj.emboj.7601965
The structure of the C-terminal actin-binding domain of talin (Journal article)
Gingras, A. R., Bate, N., Goult, B. J., Hazelwood, L., Canestrelli, I., Grossmann, J. G., . . . Critchley, D. R. (2008). The structure of the C-terminal actin-binding domain of talin. EMBO Journal, 27, 458-469.
2006
Role of vinculin in regulating focal adhesion turnover (Journal article)
Saunders, R. M., Holt, M. R., Jennings, L., Sutton, D. H., Barsukov, I. L., Bobkov, A., . . . Critchley, D. R. (2006). Role of vinculin in regulating focal adhesion turnover. European Journal of Cell Biology, 85(6), 487-500. doi:10.1016/j.ejcb.2006.01.014DOI: 10.1016/j.ejcb.2006.01.014
The Activity of the Vinculin Binding Sites in Talin Is Influenced by the Stability of the Helical Bundles That Make Up The Talin Rod (Journal article)
Patel, B., Gingras, A. R., Bobkov, A. A., Fujimoto, L. M., Zhang, M., Liddington, R. C., . . . Critchley, D. R. (2006). The Activity of the Vinculin Binding Sites in Talin Is Influenced by the Stability of the Helical Bundles That Make Up The Talin Rod. Journal of Biological Chemistry, 281(11), 7458-7467. doi:10.1074/jbc.m508058200DOI: 10.1074/jbc.m508058200
Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod<sup>,</sup> (Journal article)
Gingras, A. R., Vogel, K. -P., Steinhoff, H. -J., Ziegler, W. H., Patel, B., Emsley, J., . . . Barsukov, I. L. (2006). Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod<sup>,</sup>. Biochemistry, 45(6), 1805-1817. doi:10.1021/bi052136lDOI: 10.1021/bi052136l
2005
Mapping and Consensus Sequence Identification for Multiple Vinculin Binding Sites within the Talin Rod (Journal article)
Gingras, A. R., Ziegler, W. H., Frank, R., Barsukov, I. L., Roberts, G. C. K., Critchley, D. R., & Emsley, J. (2005). Mapping and Consensus Sequence Identification for Multiple Vinculin Binding Sites within the Talin Rod. Journal of Biological Chemistry, 280(44), 37217-37224. doi:10.1074/jbc.m508060200DOI: 10.1074/jbc.m508060200
Reaction of Morphinone Reductase with 2-Cyclohexen-1-one and 1-Nitrocyclohexene (Journal article)
Messiha, H. L., Munro, A. W., Bruce, N. C., Barsukov, I., & Scrutton, N. S. (2005). Reaction of Morphinone Reductase with 2-Cyclohexen-1-one and 1-Nitrocyclohexene. Journal of Biological Chemistry, 280(11), 10695-10709. doi:10.1074/jbc.m410595200DOI: 10.1074/jbc.m410595200
A Vinculin Binding Domain from the Talin Rod Unfolds to Form a Complex with the Vinculin Head (Journal article)
Fillingham, I., Gingras, A. R., Papagrigoriou, E., Patel, B., Emsley, J., Critchley, D. R., . . . Barsukov, I. L. (2005). A Vinculin Binding Domain from the Talin Rod Unfolds to Form a Complex with the Vinculin Head. Structure, 13(1), 65-74. doi:10.1016/j.str.2004.11.006DOI: 10.1016/j.str.2004.11.006
2004
Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle (Journal article)
Papagrigoriou, E., Gingras, A. R., Barsukov, I. L., Bate, N., Fillingham, I. J., Patel, B., . . . Emsley, J. (2004). Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle. The EMBO Journal, 23(15), 2942-2951. doi:10.1038/sj.emboj.7600285DOI: 10.1038/sj.emboj.7600285
Atomic Resolution Structures and Solution Behavior of Enzyme-Substrate Complexes of Enterobacter cloacae PB2 Pentaerythritol Tetranitrate Reductase (Journal article)
Khan, H., Barna, T., Harris, R. J., Bruce, N. C., Barsukov, I., Munro, A. W., . . . Scrutton, N. S. (2004). Atomic Resolution Structures and Solution Behavior of Enzyme-Substrate Complexes of Enterobacter cloacae PB2 Pentaerythritol Tetranitrate Reductase. Journal of Biological Chemistry, 279(29), 30563-30572. doi:10.1074/jbc.m403541200DOI: 10.1074/jbc.m403541200
A stereodivergent asymmetric approach to difluorinated aldonic acids (Journal article)
Audouard, C., Barsukov, I., Fawcett, J., Griffith, G. A., Percy, J. M., Pintat, S., & Smith, C. A. (n.d.). A stereodivergent asymmetric approach to difluorinated aldonic acids. Chem. Commun., (13), 1526-1527. doi:10.1039/b405067cDOI: 10.1039/b405067c
2003
Phosphatidylinositol Phosphate Kinase Type 1γ and β1-Integrin Cytoplasmic Domain Bind to the Same Region in the Talin FERM Domain (Journal article)
Barsukov, I. L., Prescot, A., Bate, N., Patel, B., Floyd, D. N., Bhanji, N., . . . Critchley, D. R. (2003). Phosphatidylinositol Phosphate Kinase Type 1γ and β1-Integrin Cytoplasmic Domain Bind to the Same Region in the Talin FERM Domain. Journal of Biological Chemistry, 278(33), 31202-31209. doi:10.1074/jbc.m303850200DOI: 10.1074/jbc.m303850200
The Inhibitor Thiomandelic Acid Binds to Both Metal Ions in Metallo-β-lactamase and Induces Positive Cooperativity in Metal Binding (Journal article)
Damblon, C., Jensen, M., Ababou, A., Barsukov, I., Papamicael, C., Schofield, C. J., . . . Roberts, G. C. K. (2003). The Inhibitor Thiomandelic Acid Binds to Both Metal Ions in Metallo-β-lactamase and Induces Positive Cooperativity in Metal Binding. Journal of Biological Chemistry, 278(31), 29240-29251. doi:10.1074/jbc.m301562200DOI: 10.1074/jbc.m301562200
2002
Further characterization of the interaction between the cytoskeletal proteins talin and vinculin (Journal article)
BASS, M. D., PATEL, B., BARSUKOV, I. G., FILLINGHAM, I. J., MASON, R., SMITH, B. J., . . . CRITCHLEY, D. R. (2002). Further characterization of the interaction between the cytoskeletal proteins talin and vinculin. Biochemical Journal, 362(3), 761-768. doi:10.1042/bj3620761DOI: 10.1042/bj3620761
2001
Crystal structure of pentaerythritol tetranitrate reductase: “flipped” binding geometries for steroid substrates in different redox states of the enzyme (Journal article)
Barna, T. M., Khan, H., Bruce, N. C., Barsukov, I., Scrutton, N. S., & Moody, P. C. E. (2001). Crystal structure of pentaerythritol tetranitrate reductase: “flipped” binding geometries for steroid substrates in different redox states of the enzyme. Journal of Molecular Biology, 310(2), 433-447. doi:10.1006/jmbi.2001.4779DOI: 10.1006/jmbi.2001.4779
Structural consequences of site-directed mutagenesis in flexible protein domains: NMR characterization of the L(55,56)S mutant of RhoGDI (Journal article)
Golovanov, A. P., Hawkins, D., Barsukov, I., Badii, R., Bokoch, G. M., Lian, L. Y., & Roberts, G. C. (2001). Structural consequences of site-directed mutagenesis in flexible protein domains: NMR characterization of the L(55,56)S mutant of RhoGDI. Eur J Biochem, 268(8), 2253-2260. Retrieved from http://www.ncbi.nlm.nih.gov/
Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI (Journal article)
Golovanov, A. P., Chuang, T. -H., DerMardirossian, C., Barsukov, I., Hawkins, D., Badii, R., . . . Roberts, G. C. K. (2001). Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI. Journal of Molecular Biology, 305(1), 121-135. doi:10.1006/jmbi.2000.4262DOI: 10.1006/jmbi.2000.4262
2000
Mapping the binding site for the GTP-binding protein Rac-1 on its inhibitor RhoGDI-1 (Journal article)
Lian, L. Y., Barsukov, I., Golovanov, A. P., Hawkins, D. I., Badii, R., Sze, K. H., . . . Roberts, G. C. (2000). Mapping the binding site for the GTP-binding protein Rac-1 on its inhibitor RhoGDI-1. Structure, 8(1), 47-55. Retrieved from http://www.ncbi.nlm.nih.gov/
1997
1H, 15N and 13C NMR resonance assignment, secondary structure and global fold of the FMN-binding domain of human cytochrome P450 reductase (Journal article)
Barsukov, I., Modi, S., Lian, L. Y., Sze, K. H., Paine, M. J., Wolf, C. R., & Roberts, G. C. (1997). 1H, 15N and 13C NMR resonance assignment, secondary structure and global fold of the FMN-binding domain of human cytochrome P450 reductase. J Biomol NMR, 10(1), 63-75. Retrieved from http://www.ncbi.nlm.nih.gov/
1996
The Conformation of Coenzyme A Bound to Chloramphenicol Acetyltransferase Determined by Transferred NOE Experiments (Journal article)
Barsukov, I. L., Lian, L. -Y., Ellis, J., Sze, K. -H., Shaw, W. V., & Roberts, G. C. K. (1996). The Conformation of Coenzyme A Bound to Chloramphenicol Acetyltransferase Determined by Transferred NOE Experiments. Journal of Molecular Biology, 262(4), 543-558. doi:10.1006/jmbi.1996.0534DOI: 10.1006/jmbi.1996.0534
1995
Role of the Active-Site Carboxylate in Dihydrofolate Reductase: Kinetic and Spectroscopic Studies of the Aspartate 26 .fwdarw. Asparagine Mutant of the Lactobacillus casei Enzyme (Journal article)
Basran, J., Casarotto, M. G., Barsukov, I. L., & Roberts, G. C. K. (1995). Role of the Active-Site Carboxylate in Dihydrofolate Reductase: Kinetic and Spectroscopic Studies of the Aspartate 26 .fwdarw. Asparagine Mutant of the Lactobacillus casei Enzyme. Biochemistry, 34(9), 2872-2882. doi:10.1021/bi00009a018DOI: 10.1021/bi00009a018
1994
Protein-ligand interactions: exchange processes and determination of ligand conformation and protein-ligand contacts (Journal article)
Lian, L. Y., Barsukov, I. L., Sutcliffe, M. J., Sze, K. H., & Roberts, G. C. (1994). Protein-ligand interactions: exchange processes and determination of ligand conformation and protein-ligand contacts. Methods Enzymol, 239, 657-700. Retrieved from http://www.ncbi.nlm.nih.gov/
