Biochemistry BSc (Hons)

Key information


  • Course length: 3 years
  • UCAS code: C700
  • Year of entry: 2020
  • Typical offer: A-level : ABB / IB : 33 / BTEC : D*DD in relevant diploma
life-sciences-4

Module details

Programme Year One

In addition to core modules, you choose one module from the indicative optional module list.

Year One Compulsory Modules

  • Biochemical Methods (LIFE122)
    Level1
    Credit level7.5
    SemesterSecond Semester
    Exam:Coursework weighting100:0
    Aims

    This module aims to:

    Introduce students to a range of practical skills, analytical techniques and their associated calculations that are applicable to many fields of modern biology;

    Explain to students the importance of working safely in the laboratory in accord with Health and Safety protocols and good working practices;

    Train students how to observe and record experiments, and how to present and analyse data;

    Develop experimental skills that will be used in subsequent practicals and project work;

    Demonstrate the relevance of experimental skills across all biological disciplines and the essential relationship between quantitative skills and key skills;

    Develop knowledge and understanding in biochemistry, biotechnology and biomedicine, and ability to apply, evaluate and interpret this knowledge to solve problems.

    Learning Outcomes

    (LO1) This practical, lab-based module will enable students to:

    record, evaluate and interpret qualitative and quantitative experimental data, and record procedures and protocols;

    (LO2) Use a knowledge of the principles behind several practical laboratory techniques to perform underpinning calculations, plan and execute a series of experiments

    (LO3) use laboratory equipment correctly and safely to generate data;

    (LO4) identify, formulate and test hypotheses in relation to laboratory based experimental design;

    (S1) critical and creative thinking

    (S2) Problem solving

    (S3) engage in team-working

    (S4) manage time effectively

  • Biochemistry and Biomedical Sciences (LIFE102)
    Level1
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting80:20
    Aims

    After successful completion of this module, students will be able to:

    Describe the major dietary components for humans and other organisms, and the processes that result in their digestion and absorption;

    Explain the mechanisms and processes that regulate carbohydrate, fat and protein metabolism;

    Define how imbalances in nutrition can lead to lifestyle diseases and how genetic or infectious diseases can result in impaired ability to generate energy;

    Develop knowledge and understanding in biochemistry and biomedicine, and ability to apply, evaluate and interpret this knowledge to solve problems.

    Learning Outcomes

    (LO1) On successful completion of this module, the students should be able to:

    Describe the important groups of diseases affecting humans and other organisms;

    (S1) Lifelong learning skills

  • Experimental Skills in Current Biology (LIFE107)
    Level1
    Credit level15
    SemesterWhole Session
    Exam:Coursework weighting30:50
    Aims

    1.       Introducestudents to a range of practical skills and techniques that are of general usein subjects across the Life Sciences; 2.       Demonstratethe relevance of experimental skills across all biological disciplines andexplain the importance of observing good laboratory practice 3.       Trainstudents how to observe and record experiments, and how to present and analysedata  

    Learning Outcomes

    (LO1) Record procedures and protocols for experiments relating to current biology and generate, evaluate andinterpret qualitative and quantitative data

    (LO2) Identify, formulate andtest hypotheses in relation to laboratory- based experiments in current biology

    (LO3) Use laboratory equipment correctly and safely according to good laboratory practice and observing Health and Safety rules

    (LO4) Demonstrate a range of laboratory skills when undertaking experiments in current biology

    (S1) Organisational skills

    (S2) Communication skills

    (S3) Information technology (application of) adopting, adapting and using digital devices, applications and services

    (S4) Positive attitude/ self-confidence A 'can-do' approach, a readiness to take part and contribute; openness to new ideas and the drive to make these happen

    (S5) Numeracy (application of) manipulation of numbers, general mathematical awareness and its application in practical contexts (e.g. measuring, weighing, estimating and applying formulae)

    (S6) Problem solving/ critical thinking/ creativity analysing facts and situations and applying creative thinking to develop appropriate solutions.

    (S7) Self-management readiness to accept responsibility (i.e. leadership), flexibility, resilience, self-starting, initiative, integrity, willingness to take risks, appropriate assertiveness, time management, readiness to improve own performance based on feedback/reflective learning

    (S8) Team (group) working respecting others, co-operating, negotiating / persuading, awareness of interdependence with others

  • Grand Challenges in Biology (LIFE105)
    Level1
    Credit level7.5
    SemesterFirst Semester
    Exam:Coursework weighting60:40
    Aims

    To encourage students to become aware of the themes that are driving biological research in Liverpool and globally;
    To engage students with their programme of study;
    To excite student interest in their subject and the way it relates to the challenges that face us all;
    To foster the development of study skills that will equip students to investigate research topics and communicate their findings and views on them.

    Learning Outcomes

    (LO1) To identify the grand challenges that face biological scientists

    (LO2) To put into context the advances that science makes possible and the ethical issues associated with meeting the Grand Challenges

    (LO3) To evaluate different approaches to the resolution of scientific questions

    (LO4) To conduct an independent piece of research and report their findings to their peers

    (S1) Communication, listening and questioning respecting others, contributing to discussions, communicating in a foreign language, influencing, presentations

    (S2) Global perspectives demonstrate international perspectives as professionals/citizens; locate, discuss, analyse, evaluate information from international sources; consider issues from a variety of cultural perspectives, consider ethical and social responsibility issues in international settings; value diversity of language and culture

    (S3) Information literacy online, finding, interpreting, evaluating, managing and sharing information

    (S4) Literacy application of literacy, ability to produce clear, structured written work and oral literacy - including listening and questioning

    (S5) Positive attitude/ self-confidence A 'can-do' approach, a readiness to take part and contribute; openness to new ideas and the drive to make these happen

    (S6) Team (group) working respecting others, co-operating, negotiating / persuading, awareness of interdependence with others

  • Molecules and Cells (LIFE101)
    Level1
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting80:20
    Aims

    After successful completion of this module, students will be able to:

    Recognise the basic of structure, composition and function of cells;

    Explain core concepts relating to the organisation and specialisation of eukaryotes, prokaryotes and viruses;

    Define the cellular components involved in the regulation of key functions such as the generation of energy, movement, cell growth and division and differentiation;

    Describe the latest techniques that are used in cell biology to determine cell structure and function;

    Develop in students the knowledge and understanding of the subject and the ability to apply, evaluate and interpret this knowledge to solve problems.

    Learning Outcomes

    (LO1) On successful completion of the module students will be able to:

    Describe how cells arose and their structural features;

    (LO2) Compare and contrast eukaryotic and prokaryotic cells;

    (LO3) Identify the different ways cells manipulate energy;

    (LO4) Define the molecular basis of the processes by which cells grow, replicate, communicate, interact with their environment, move and die;

    (LO5) Describe the functional importance of cell specialisation and cooperation in tissues.

    (S1) Skills in using technology - Information accessing

  • Evolution (LIFE103)
    Level1
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting80:20
    Aims

    This module aims to:
    Describe fundamental genetic mechanisms that are essential for the function and evolution of life;

    Introduce students to fundamental evolutionary concepts and theories, showing how genetic mechanisms help determine the patterns of observed evolution;

    Apply evolutionary concepts to a broad selection of areas of Life Sciences;

    Develop in students the knowledge and understanding of the subject and the ability to apply, evaluate and interpret this knowledge to solve problems in biology.

    Learning Outcomes

    (LO1) Recall how cells evolved

    (LO2) Identify the causes of evolutionary change in populations

    (LO3) Recognize the consequences of evolutionary change for patterns of biological diversity within and amongst populations

    (LO4) Recall fundamental genetic mechanisms (heredity, mutation, meiosis, sex) and show how they influence evolutionary change in populations

    (LO5) Recognize the widespread applicability of evolutionary ideas across the Life Sciences

    (S1) Lifelong learning skills

  • Introduction to Genetics and Development (LIFE128)
    Level1
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting80:20
    Aims

    1) To develop students’ knowledge of the genetic basis of heredity and the application of modern genetic techniques across biology and medicine.

    2) To develop knowledge and understanding of the major events that comprise embryogenesis and of the genetic and cell-biological mechanisms that underpin developmental events.

    3) To enable students to appreciate the ethical issues surrounding modern genetic technology.

    Learning Outcomes

    (LO1) Recognise how germ cell development, meiosis and molecular mechanisms lead to variation in offspring and be able to interpret patterns of inheritance.

    (LO2) Choose and know how to apply relevant molecular technologies to study genes, and at an introductory level to create genetically modified organisms and treat genetic disease.

    (LO3) Identify the fundamental mechanisms that regulate development and the events that lead to germ layer formation and organogenesis.

    (LO4) Identify the experimental models and methods used to investigate the mechanisms that regulate development.

    (LO5) Identify the general properties of stem cells, their role in development and their therapeutic potential.

    (LO6) Discuss the ethical issues associated with developments in genetics, development and stem cell therapies.

    (S1) Effective Group working

    (S2) Structure and communicate ideas effectively

    (S3) Access and evaluate information

    (S4) Evaluate own performance and working standards and those of others

  • Communication and Study Skills for the Life Sciences (LIFE130)
    Level1
    Credit level7.5
    SemesterWhole Session
    Exam:Coursework weighting0:100
    Aims

    to provide students with study and communication skills for higher education in the Life Sciences;

    to develop students’ ability to reflect on their progress and use feedback to identify opportunities for personal development;

    to develop students’ appreciation of the application of these skills to future employment.

    Learning Outcomes

    (LRE1) Structure and communicate ideas effectively, both orally and in writing

    (LRE2) Discuss and appropriately use relevant literature

    (S1) Evaluate and evidence own performance using reflective practice

    (S2) Manage time, and work to deadlines

    (S3) Find relevant and appropriate information and use IT effectively

  • Quantitative Skills for the Life Sciences (LIFE113)
    Level1
    Credit level7.5
    SemesterFirst Semester
    Exam:Coursework weighting100:0
    Aims

    This module aims to:

    1. Develop in students the essential quantitative and digital skills that they will require to be competent Life Scientists.

    2. Develop critical thinking and problem solving skills.

    3. Introduce students to the use of basic digital tools for handling data and visualising data.

    4. Introduce students to computer programming (fundamental component of digital technology) that will enable them to perform robust statistical analysis of biological datasets.

    Learning Outcomes

    (L4-0) Solve numerical problems in a biological context.

    (L4-1) Use digital tools for data processing and visualisation.

    (L4-2) Understand how to construct and test experimental hypotheses.

    (L4-4) Use a programming language for analysis and visualisation of large data sets and the application of statistics.

Year One Optional Modules

  • Introduction to Physiology and Pharmacology (LIFE106)
    Level1
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting80:20
    Aims

    This module aims to:

    Provide students with a grounding in the concepts and principles that underlie human systems biology;

    Introduce the concepts of interactions of drugs and other exogenous chemicals on biological processes;

    Develop concepts of drug absorption and the relationship between chemical structure and drug action;

    Develop knowledge and understanding in physiology and pharmacology, and ability to apply, evaluate and interpret this knowledge to solve problems in these disciplines.

    Learning Outcomes

    (LO1) On successful completion of this module, the students will be able to:
    Describe homeostasis and its maintenance;

    (LO2) Define osmosis and hydrostatic pressure;

    (LO3) Outline the fundamentals of membrane potentials and how they are influenced;

    (LO4) Explain the roles played in various body systems in organism maintenance.

    (LO5) Distinguish how body systems interact in response to external stressors

    (LO6) Define the way in which pharmacology is studied and drugs are developed

    (LO7) Describe the properties of receptors

    (LO8) Identify the chemical interactions between drugs and receptors

    (LO9) Define and use the terms absorption, distribution and metabolism of drugs

    (S1) Lifelong learning skills

  • Microbiology (LIFE110)
    Level1
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting80:20
    Aims

    This module aims to:

    Describe how microbes play crucial roles in maintaining the natural environment;

    Explain the role of microbes in disease processes and how the immune system protects against infections;

    Highlight the roles of microbes in biotechnological processes;

    Develop knowledge and understanding in microbiology, and ability to apply, evaluate and interpret this knowledge to solve problems in Microbiology.

    Learning Outcomes

    (LO1) On successful completion of this module, the students will be able to:

    Identify appropriate techniques for assessing microbial diversity with particular reference to bacteria and fungi;

    (LO2) Describe the structure and significance of microbial communities involving these species

    (LO3) Explain the physiological properties and adaptations that enable microbes to colonise diverse environments

    (LO4) Define the roles of microbes as commensals and pathogens and mechanisms by which they interact with the host;

    (LO5) Describe the roles that microbes play in nutrient and biomass recycling;

    (S1) Lifelong learning skills

Programme Year Two

In addition to core modules, you choose two modules from the indicative optional module list.

Year Two Compulsory Modules

  • Advanced Biochemical Techniques (LIFE224)
    Level2
    Credit level7.5
    SemesterSecond Semester
    Exam:Coursework weighting0:100
    Aims

    This module aims to:

    Provide students with a practical training in a number of techniques used in biochemistry, including analysis of enzyme activity and stability and protein purification and analysis using chromatography and electrophoresis;

    Develop in students the knowledge, understanding and ability to design experiments, and to apply, evaluate and interpret experimental data to solve problems in biochemistry and molecular cell biology.

    Learning Outcomes

    (LO1) Present, critically evaluate and interpret qualitative and quantitative data, and record procedures and protocols;

    (LO2) Develop team-working and individual skills, learn to manage time effectively and use laboratory equipment correctly and safely to generate data;

    (LO3) Plan and execute a series of biochemical experiments to analyse protein structure and function;

    (LO4) Analyse data, interpret its validity and apply statistical analyses.

    (S1) Students will also develop independent learning, team-working and self-evaluation skills.

    (S2) Problem solving/ critical thinking/ creativity analysing facts and situations and applying creative thinking to develop appropriate solutions.

  • Cell Signalling in Health and Disease (LIFE202)
    Level2
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting80:20
    Aims

    This module aims to:

    Provide students with knowledge and understanding of the molecular mechanisms that allow cells to communicate with each other;

    Explain the general principles of these signalling mechanisms and then describe some of these in more detail;

    Illustrate how defects in these signalling processes can result in a variety of diseases;

    Outline the techniques that are used to investigate and define these pathways and to describe how these techniques are used in drug discovery programmes of research;

    Develop in students the ability to apply, evaluate and interpret this knowledge and understanding, to solve problems in molecular cell biology.

    Learning Outcomes

    (LO1) On successful completion of this module, the students should be able to: Describe the fundamental features of a range of common cell signalling mechanisms;

    (LO2) Explain how cell signalling processes may be defective, or modified, in a variety of different diseases;

    (LO3) Demonstrate knowledge of the molecular and biochemical nature and role of the different components of intracellular signalling pathways;

    (LO4) Demonstrate knowledge and critical understanding of the principles of cell signalling, and how this knowledge has been applied to solve problems in biological science.

    (S1) Students will also develop independent learning and self-evaluation skills

  • E-biology: Informatics for Life Sciences (LIFE225)
    Level2
    Credit level7.5
    SemesterFirst Semester
    Exam:Coursework weighting99:0
    Aims

    Provide students with a practical appreciation of the nature and significance of digital data;

    Expose students to bioinformatics tools used in the analysis of data from areas such as genome sequencing, gene expression, and protein structure studies;

    Enable students to utilize digital data for understanding higher order phenomena within cells such as metabolism, gene regulation, and protein-protein interaction;

    Develop students’ knowledge and understanding of the subject and the ability to apply, evaluate, and interpret this knowledge to solve problems in biotechnology, biomedicine, and molecular cell biology.

    Learning Outcomes

    (LO1) Apply informatics tools in the discovery, evaluation, and acquisition of biological data;

    (LO2) Analyse and evaluate datasets of broad biological relevance, using tasks and workflows that will prepare them for third-year projects;

    (LO3) Use local and web-based tools for data analysis, management and collaborative working; 

    (LO4) Design research methods in bioinformatics to solve biological problems.

    (S1) Digital scholarship participating in emerging academic, professional, and research practices that depend on digital systems;

    (S2) Information technology (application of) adopting, adapting and using digital devices, applications, and services;

    (S3) Problem solving, critical thinking, creativity; analysing facts and situations and applying creative thinking to develop appropriate solutions.

  • E-biology: Informatics for Life Sciences (s2) (LIFE242)
    Level2
    Credit level7.5
    SemesterSecond Semester
    Exam:Coursework weighting99:0
    Aims

    Provide students with a practical appreciation of the nature and significance of digital data;

    Expose students to bioinformatics tools used in the analysis of data from areas such as genome sequencing, gene expression, and protein structure studies;

    Enable students to utilize digital data for understanding higher order phenomena within cells such as metabolism, gene regulation, and protein-protein interaction;

    Develop students’ knowledge and understanding of the subject and the ability to apply, evaluate and interpret this knowledge to solve problems in biotechnology, biomedicine, and molecular cell biology.

    Learning Outcomes

    (LO1) Apply informatics tools in the discovery, evaluation and acquisition of biological data.;

    (LO2) Analyse and evaluate datasets of broad biological relevance, using tasks and workflows that will prepare them for third-year projects.;

    (LO3) Use local and web-based tools for data analysis, management and collaborative working;

    (LO4) Design research methods in bioinformatics to solve biological problems.

    (S1) Digital scholarship participating in emerging academic, professional and research practices that depend on digital systems;

    (S3) Problem solving, critical thinking, creativity; analysing facts and situations and applying creative thinking to develop appropriate solutions.

    (S2) Information technology (application of) adopting, adapting and using digital devices, applications, and services;

  • Essential Skills for the Life Sciences 2 (LIFE223)
    Level2
    Credit level15
    SemesterWhole Session
    Exam:Coursework weighting30:70
    Aims

    Enhance the development of the essential life science skills that students will require to improve their study skills;

    Enable students to analyse and interpret scientific data and communicate results;

    Enhance the employability prospects of students and career awareness.

    Learning Outcomes

    (LO1) Use a range of mathematical and numerical skills relevant to all biologists to summarise and interpret real-world data using graphs and tables.

    (LO2) Develop and test hypotheses within the context of experimental design and within a range of biological fields, select appropriate quantitative methods to answer questions;

    (LO3) To develop programming skills relevant for statistical analysis and apply appropriate statistical and other analysis packages to analyse data;

    (LO4) Recognise the moral and ethical issues of scientific investigations and discuss ethical standards and professional codes of conduct. 

    (LRE1) Structure and communicate ideas effectively, both orally and in writing;

    (LRE2) Discuss and appropriately use relevant literature

    (LRE3) Time management

    (S1) Communication, listening and questioning and respecting others by contributing to discussions.

    (S2) Team (group) working respecting others, co-operating, negotiating / persuading, awareness of interdependence with others

    (S3) Independent working and readiness to improve own performance based on feedback/reflective learning.

    (S4) Problem solving/ critical thinking/ creativity analysing facts and situations and applying creative thinking to develop appropriate solutions.

  • From Genes to Proteins (LIFE201)
    Level2
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting70:30
    Aims

    To provide students with a general understanding of the major molecularmechanisms involved in gene expression and its regulation including both eukaryotic and prokary otic systems, extending from transcription though totranslation and the post-translational modification of proteins.   To provide students with a conceptual appreciation of key scientific approachesused to study these processes.   To raise awareness in students ofpotential applications and develop their appreciation of the fundamental nature, conservation andimportance of these systems.  

    Learning Outcomes

    (LO1) To explain the processes of transcription and translation and their regulation, the differences between them in prokaryotes and eukaryotes and how these are affected in disease.

    (LO2) To elucidate the post-translational events in eukaryotic cells, and how these produce a final functional protein from a primary translation product.

    (LO3) To evaluate the techniques used to investigate the processes of transcription and translation.

    (S1) Students will also develop independent learning and self-evaluation skills.

    (S2) Problem solving/ critical thinking/ creativity analysing facts and situations and applying creative thinking to develop appropriate solutions.

  • Molecular Science (LIFE237)
    Level2
    Credit level7.5
    SemesterFirst Semester
    Exam:Coursework weighting60:40
    Aims

    Provide students w ith practical experience in a number of techniques used in molecular biology; Equip student to perform analysis of DNA fragments by agarose gel electrophoresis; Introduce students to PCR based-assays for gene cloning and d emonstrate methods used for cloning, and analysing genes Develop in  students knowledge and understanding in biomedicine, biotechnology and molecular cell biology, and the ability to apply, evaluate and interpret this knowledge to solve biomolecular problems.

    Learning Outcomes

    (LO1) Present , evaluate critcally and interpret qualitative and quantitative molecular biology data;

    (LO2) Plan and execute a series of molecular biology experiments to demonstrate practical skills in molecular biology;

    (LO3) Analyse and interpret the validity of experimental data;

    (LO4) Summarise scientific investigations

    (S1) Problem solving/ critical thinking/ creativity analysing facts and situations and applying creative thinking to develop appropriate solutions.

    (S2) Improve time management to successfully complete experiments

  • Structure and Dynamics of Macromolecules (LIFE203)
    Level2
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting85:15
    Aims

    This module aims to:

    Provide students with knowledge and understanding of the latest methodologies and techniques that are used to study the fine detail of macromolecules;

    Explain how the structure of macromolecules determines their function Describe how altered protein function can result in disease;
    Outline the importance of applying the techniques used to solve macromolecular structure and function can be applied to drug discovery programmes;

    Develop knowledge and understanding in structural biology, and ability to apply, evaluate and interpret this knowledge to solve problems.

    Learning Outcomes

    (LO1) Explain the key chemical and structural features of proteins and describe how these features relate to biological function

    (LO2) Discuss how knowledge of biomolecular structure relates to applications in medicine, the pharmaceutical industry and bio- and nano-technology

    (LO3) Describe techniques used to determine protein structure and dynamics and discuss the advantages and limitations of each technique

    (LO4) Discuss the chemical and structural basis of some central biological processes by describing the structure and function of enzymes, membrane proteins and macromolecular complexes of biomolecules

    (LO5) Discuss the latest ideas on the evolution of protein function

    (LO6) Describe the principles of structural biology, and how this knowledge has been applied to solve fundumental biological questions

    (LO7) Conduct basic analysis of optical and NMR spectra of proteins

    (S1) Information literacy online, finding, interpreting, evaluating, managing and sharing information

  • Techniques in Cell Biology (LIFE227)
    Level2
    Credit level7.5
    SemesterFirst Semester
    Exam:Coursework weighting60:40
    Aims

    1. Provide students with practical training in the use of equipment and techniques routinely used in cell biology.

    2. Enhance students acquisition of fundamental research skills; including, information gathering, scientific drawing, report writing and statistical analyses.

    3. Provide students with an understanding of the processes involved in the collection, interpretation and presentation of biological data.

    Learning Outcomes

    (LO1) Present, evaluate and interpret qualitative and quantitative data, and record procedures and protocols;

    (LO2) Manage time effectively to plan and execute a series of experiments

    (LO3) Use microscopes and other lab equipment correctly to efficiently andsafely conduct a series of experiments

    (LO4) Analyse data, interpret validity and apply statistical analyses;

    (LO5) Apply the principles of biotechnology, biomedicine and molecular cell biology  to practical experiments. 

    (S1) Problem solving/ critical thinking/ creativity analysing facts and situations and applying creative thinking to develop appropriate solutions.

    (S2) Team (group) working respecting others, co-operating, negotiating / persuading, awareness of interdependence with others

Year Two Optional Modules

  • Biotechnology (LIFE210)
    Level2
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting80:20
    Aims

    Introduce students to the ways in which biology is utilised for commercial purposes;

    Develop knowledge and understanding of the production of antibiotics, biomass, single cell protein, biopolymers and vaccines;

    Develop knowledge and understanding in biotechnology, and the ability to apply, evaluate and interpret this knowledge to solve problems in biotechnology.

    Learning Outcomes

    (LO1) Identify the stages required for commercial production of microbial products;

    (LO2) Discuss the problems inherent in isolation, strain improvement and growth of microorganisms on a large scale;

    (LO3) Explain specific commercial processes via studies of such processes as antibiotic production, large-scale manufacture of enzymes and brewing;

    (LO4) Discuss how understanding of protein structure can lead to the generation of therapeutic   compounds;

    (LO5) Interpret how proteins and antibodies may be engineered and produced on an industrial scale for commercial applications;

    (LO6) Discuss how useful activities of enzymes may be manipulated and exploited;

    (S1) Problem solving/ critical thinking/ creativity analysing facts and situations and applying creative thinking to develop appropriate solutions.

    (S2) Information literacy online, finding, interpreting, evaluating, managing and sharing information

  • Principles of Pharmacology (LIFE207)
    Level2
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting80:20
    Aims

    This module aims to:   Develop an understanding of the quantitative aspects of drug action on cellular receptors; Demonstrate the relationship between drug efficacy and chemical structure; Introduce the basic principles of pharmacokinetics, outline the relationship between drug concentration and response, and include an introduction to the principles of toxicity of drugs and their metabolites; Provide knowledge of the molecular biology of receptors; Develop knowledge and understanding in pharmacology, and the ability to apply, evaluate and interpret this knowledge to solve pharmacological problems.

    Learning Outcomes

    (LO1) On successful completion of this module, the students should be able to: Describe quantitative aspects of drug action;

    (LO2) Define the relationship between drug efficacy and chemical structure;

    (LO3) State key pharmacokinetic concepts such as clearance, volume of distribution, half life and steady state and to solve problems involving these parameters;

    (LO4) Demonstrate the role of drug concentrations in determining response to treatment;

    (LO5) Describe early biochemical events after drug administration that are of toxicological and biochemical significance;

    (LO6) Describe the principles of selective toxicity and their application to both self and non-self targets;

    (LO7) Demonstrate knowledge and critical understanding of the principles of pharmacology, and how this knowledge has been applied to solve problems.

    (S1) Students will also develop independent learning and self-evaluation skills.

  • The Immune System in Health and Disease (LIFE221)
    Level2
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting80:20
    Aims

    This module aims to:

    Develop  students knowledge of the immune system and its role in protection against disease;

    Develop in students an appreciation of the importance of different immune mechanisms in different circumstances, and how these can be evaded;

    Enable students to evaluate and appreciate the consequences of immune system dysfunctions in disease.

    Learning Outcomes

    (LO1) Identify the main components of the mammalian immune system

    (LO2) Assess the contribution of innate and adaptive immune mechanisms to host defences

    (LO3) Assess the mechanisms that permit recognition of an infinitely diverse microflora

    (LO4) Discuss the impact of malfunction of immune processes on human health, and explain the bases of autoimmunity and allergy together with the mechanisms by which these can be minimised

    (LO5) Discuss how dysfunction of immune system constituents can cause disease

    (S1) Problem solving skills

    (S2) Organisational skills

  • The Multicellular Organism: Tissues, Development, Regeneration and Aging (LIFE205)
    Level2
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting80:20
    Aims

    Extend students' knowledge of the structure and function of fundamental tissues, such as epithelial and connective tissue and of specialised tissues;

    Develop students' ability to discuss the mechanisms by which cells differentiate to form different tissues;

    Equip students to explain the processes that occur during ageing with special reference to changes in key tissues such as the brain;

    Develop knowledge and understanding in human biology, and ability to apply, evaluate and interpret this knowledge to solve problems in that subject.

    Learning Outcomes

    (LO1) Describe the experimental basis underpinning the current understanding of tissue biology.

    (LO2) Explain and discuss mechanisms of ageing using selected systems as exemplars.

    (LO3) Discuss the cellular structure and organisation of different organs, and compare and contrast the molecular mechanisms involved in development and regeneration of these organs

    (LO4) Classify and compare the major types of epithelia and, explain the role of cell-cell interactions in tissue structure and the structure and function of fundamental tissues

    (S1) Students will also develop independent learning and self-evaluation skills

  • Chem038 - Organic Chemistry for Pharmacology (CHEM038)
    Level2
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting90:10
    Aims

    The aim of this module is to offer students a grounding in organic chemistry and spectroscopy that is directly relevant to Pharmacology.
    There will be a particular emphasis on relating each topic studied to pharmacological examples.

    Learning Outcomes

    (LO1) Upon successful completion of this module, a student will be able to demonstrate an understanding of the structure and bonding in a range of molecules, from simple organics to larger biologically relevant structures.

    (LO2) Upon successful completion of this module, a student will be able to demonstrate an understanding of the significant role of stereochemistry and conformation in a pharmacological setting

    (LO3) Upon successful completion of this module, a student will be able to demonstrate an understanding of an array of chemical reactions

    (LO4) Upon successful completion of this module, a student will be able to demonstrate an understanding of a range of spectroscopic methods

    (LO5) Upon successful completion of this module, a student will be able to demonstrate an understanding of the chemical principles in both the synthesis of biologically relevant structures and their interactions with small molecules

    (LO6) Upon successful completion of this module, a student will be able to apply these concepts and principles to process and solve unseen organic chemistry problems.

    (S1) Improving own learning/performance - Reflective practice

    (S2) Critical thinking and problem solving - Problem identification

    (S3) Personal attributes and qualities - Resilience

    (S4) Students will develop independent learning and self-evaluation skills

  • Molecular and Medical Genetics (LIFE208)
    Level2
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting100:0
    Aims

    This module aims to:

    Introduce students with an interest in genetics and molecular biology to the range of biological mechanisms that control the structure and stability of the genetic material;

    Describe how changes in the structure and stability of DNA can impact on health and disease;

    Use examples from both prokaryotes and eukaryotes to develop principles that help explain problems associated with medical/clinical genetics;

    Develop knowledge and understanding in genetics and molecular biology, and ability to apply, evaluate and interpret this knowledge to solve problems.

    Learning Outcomes

    (LO1) On successful completion of this module, the students should be able to: Describe the principles of DNA replication, DNA damage and mutation, DNA repair, DNA recombination, genetic transfer systems and transposition, cell cycle control and cell division, genetic mapping and cytogenetics;

    (LO2) Explain how these processes underpin an understanding of the genetic basis of human health and disease;

    (LO3) Demonstrate that they can solve problems by applying the above knowledge to identify genes underlying disease and the likely causes of DNA mutations;

    (LO4) Demonstrate knowledge and critical understanding of the principles of genetics and molecular biology, and how this knowledge has been applied to solve problems.

    (S1) Improving own learning/performance - Record-keeping

  • Drug Action (LIFE206)
    Level2
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting100:0
    Aims

    Enable students to develop their understanding of the cardiovascular, endocrine and central nervous systems and the mechanisms by which drugs interact with physiological processes operating within each of these systems;
    Provide an insight into the mechanisms of immune function and dysfunction, and the actions of drugs that target the im mune system;
    Give students a grounding in the fundamental principles of signal transduction from metabotropic receptors, and their significance for drug action;
    P rovide and overview of the overall drug development process, with a focus on the safety and efficacy tests applied during clinical trials, and the value-for-money tests applied during NICE approval;
    Develop knowledge and understanding in pharmacology, and ability to apply, evaluate and interpret this knowledge to solve problems.

    Learning Outcomes

    (LO1) Identify the effects of drugs on the CNS and demonstrate an understanding of how drugs may be used to treat neurological and neuropsychiatric disorders;

    (LO2) Describe the action of drugs in the cardiovascular system and their role in the treatment of cardiovascular disease;

    (LO3) Compare the effects of drugs on the kidney, the endocrine system and the gastrointestinal tract;

    (LO4) Describe the principles underlying the effects of drugs on the immune system and the treatment of autoimmune disease;

    (LO5) Apply knowledge how the signal transduction pathways can be modulated to enhance cancer therapy ;

    (LO6) Apply the knowledge of the regulatory framework underlying the testing and approval of drugs;

    (S1) Problem solving skills

    (S2) Commercial awareness

    (S3) International awareness

    (S4) Lifelong learning skills

  • Endocrine and Neuro-physiology (LIFE204)
    Level2
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting70:30
    Aims

    Explain the essential background knowledge to understand basic neuroscience;

    Describe the basic principles of operation of nervous system, systematic and sensory neurophysiology, excitotoxicity and behaviour;

    Provide an understanding of physiological homeostatic regulatory mechanisms, with particular regard to the endocrine and digestive systems;
    Develop knowledge and understanding in physiology, and ability to apply, evaluate and interpret this knowledge to solve physiological problems.

    Learning Outcomes

    (LO1) Demonstrate knowledge and critical understanding of the principles of physiology, and how this knowledge has been applied to solve physiological problems.

    (LO2) Demonstrate specific knowledge and critical understanding of physiological functions of the digestive tract and major endocrine glands and apply this to understand the interaction between the digestive, endocrine and nervous system;

    (LO3) Apply the above knowledge to the operation of some of these systems, through all the stages from transduction of a stimulus to conscious perception, the regulatory mechanisms employed by them, their importance in maintaining homeostasis and the consequences of malfunction;

    (LO4) Describe the basic principles of the nervous system, systematic and sensory neurophysiology, excitotoxicity and behaviour; and the characteristics of nerve cells that allow them facilitate the reception, processing and transmission of information;

    (S1) Students will also develop independent learning and self-evaluation skills

  • Virology (LIFE209)
    Level2
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting80:20
    Aims

    This module aims to develop in students:

    The ability to explain the fundamental features and properties of viruses and viral infections;

    Knowledge and understanding of the use and development of molecular biology technologies in virology;

    The capacity to describe problems associated with viruses and their control, and identify positive applications of viruses;

    Knowledge and understanding in virology, and the ability to apply, evaluate and interpret this knowledge to solve problems in virology.

    Learning Outcomes

    (LO1) On successful completion of this module, the students should be able to: Explain basic terms and terminologies used in virology and describe virus particle structure;

    (LO2) Identify different virus infection life cycles in prokaryotes and eukaryotes, describing the role of key viral proteins in viral life cycles;

    (LO3) Describe impact of viruses on public health, explain how viruses may spread between different species and the concept of species-barrier;

    (LO4) Describe the use of diagnostic tools to detect, quantify, and monitor viruses;

    (LO5) Explain the role of immune system in combating viral infections in plants, invertebrates and mammals;

    (LO6) Demonstrate knowledge and critical understanding of the principles of virology, and how this knowledge has been applied to solve problems.

    (S1) Students will also develop independent learning and self-evaluation skills

Programme Year Three

Students spend about three days per week throughout the whole of the 3rd year on their research projects, usually in one of the laboratories of the molecular medicine, cell signalling, chemical biology or structural biology research groups. Students may also take projects within the Schools of Medicine, Veterinary Science, Dentistry, or even in local hospitals.

Year Three Compulsory Modules

  • Advanced Skills in Biochemistry (LIFE301)
    Level3
    Credit level15
    SemesterWhole Session
    Exam:Coursework weighting0:100
    Aims

    To develop the students' science presentation skills in various formats and to various target audiences;

    To enhance the students' ability to search, identify, apply, critically evaluate, and interpret biochemical knowledge to solve complex problems;

    To provide advice, inspiration and guidance for career development and employability.

    Learning Outcomes

    (LO1) To work in groups to produce and present a scientific poster in the context of biochemistry;

    (LO2) To analyse, summarise, present and critically review evidence from scientific publications in the context of biochemistry;

    (LO3) To communicate, in writing, scientific facts and data to both expert and lay audiences

    (LO4) To synthesise information on topical issues within biochemistry

    (S1) Scientific Communication

    (S2) Teamwork;

    (S3) Digital fluency

    (S4) Critical Thinking

  • Biochemical Messengers and Signal Transduction (LIFE304)
    Level3
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting100:0
    Aims

    To enable students to evaluate and describe the latest knowledge and ideas on how cells respond to external signals and how signalling information is transferred within and between cells;

    To develop in students an understanding of the range of different strategies used by cells for generating and interpreting signalling information, including their outcomes;

    To introduce students to current knowledge of the molecular and biochemical events that lead from receptor occupancy to changes in gene expression and phenotype, with links to human diseases explained.

    Learning Outcomes

    (LO1) To compare, in both written and graphical formats, the multiple molecular processes underlying transduction of information, the key extracellular and intracellular players;

    (LO2) To assess the consequences of expression changes or mutations in signalling proteins in the context of different diseases;

    (LO3) To appraise the features of the major components and modules of signalling pathways;

    (LO4) To evaluate the usefulness of signalling proteins as targets for rational drug design. 

    (S1) Problem solving skills;

    (S2) Communication skills;

    (S3) Lifelong learning skills.

  • Genes and Cancer (LIFE302)
    Level3
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting75:25
    Aims

    To develop students’ understanding of how cancer occurs and the role of oncogenes and tumour suppressor genes in the development of human cancer;

    To develop students' understanding of the hallmarks of cancer and what are different therapeutic strategies and their limitations;

    To provide students with opportunities to critically evaluate and interpret the published literature in the field of cancer biology

    Learning Outcomes

    (LO1) To explain the molecular and cellular basis of cancer formation

    (LO2) To appraise the biological capabilities acquired during the multistep development of human tumours

    (LO3) To explain the current therapeutic strategies for cancer treatment

    (LO4) To critically evaluate how technologies such sequencing, gene expression analysis, and bio-informatics have shaped our knowledge of the mechanism of cancer progression

    (LO5) To synthesise information, critically review evidence to support conclusions, and define complex problems by applying appropriate knowledge and skills in the area of genes and cancer

    (S1) Problem solving skills

    (S2) Communication skills

  • Molecular Medicine (LIFE306)
    Level3
    Credit level15
    SemesterSecond Semester
    Exam:Coursework weighting100:0
    Aims

    To describe to students the application of molecular and computational approaches in the study and treatment of human disease;

    To use selected topics, such as regenerative medicine and the extracellular matrix, to describe specific disease processes;

    To develop in students knowledge and deep understanding in biochemistry and biomedicine, and the ability to apply, critically evaluate and interpret this knowledge to solve biological and biomedical complex problems.

    Learning Outcomes

    (LO1) To critically evaluate the usefulness of genotypic and phenotypic approaches to screening in a post-genomic context;

    (LO2) To appraise the latest developments in post-genomic science and computational biology for the development of medications and drugs;

    (LO3) To analyse our current understanding of stem cell therapeutics;

    (LO4) To evaluate the role of the extracellular matrix and its components in a number of key disease processes and their treatment.

    (LO5) The student will appraise the latest developments in post-genomic science and computational biology for the development of therapeutic approaches  

    (LO6) The student will discern the usefulness of "biological" drugs as opposed to small molecule drugs

    (LO7) The student will analyse our current understanding of stem cell therapeutics

    (S1) Problem solving skills;

    (S2) Communication skills;

    (S3) Lifelong learning skills.

  • Protein Structure, Function and Organisation (LIFE303)
    Level3
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting100:0
    Aims

    To develop in students knowledge and understanding why protein structures are important for function, and how proteins fold into functional conformations

    To provide an overview of current NMR, X-ray crystallography and proteomics-based approaches to solve fundamental and applied problems in biology and biotechnology

    To explain to students the latest techniques used to define protein structures

    Learning Outcomes

    (LO1) To discuss the prerequisites for obtaining structures such as protein foldedness and sample preparations

    (LO2) To critically evaluate the strengths and weakness of the different technologies - nuclear magnetic resonance (NMR), x-ray crystallography- mass spectrometry and how they can be used in an integrated manner

    (LO3) To discuss the latest methods of analysis of post-translational modifications of proteins and implications for cell function

    (LO4) To critically discuss how proteomics-based approaches can be used to study fundamental and applied biological problems

    (LO5) To describe in detail, current methods used for the determination and analysis of protein structures

    (S1) Problem solving skills

    (S2) IT skills

Year Three Optional Modules

  • Life Sciences Work Based Placement (LIFE399)
    Level3
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting0:100
    Aims

    To give students an opportunity to develop theirskills during a placement at a commercial, research, voluntary, or similarorganisation, reflect on their experiences and progress during the placement,and engage with relevant theory and research in the area of occupationalpsychology.

    Learning Outcomes

    (LO1) Criticallyreflect on the development of employability skills.

    (LO2) Appraise current work placement practice in relation to both employer and employee outcomes.

    (LO3) Designand justify work placement recommendations with reference to relevant theoryand research and student placement experience.

    (S1) Critical thinking and Problem solving skills

    (S2) Communication (written and oral)

    (S3) Interpersonal (self-management and teamworking) skills

    (S4) Effectiveness

    (S5) Organisational skills

    (S6) Digital literacy (use of VLOG, online reflective log)

    (S7) Technical skills (associated to the placement work)

  • Gene Expression and Development (LIFE323)
    Level3
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting99:0
    Aims

    To provide students with a systematic knowledge and critical understanding of how living organisms control their pattern of gene expression;

    To describe how patterns of gene expression respond to environmental factors during growth and development;

    To explain current knowledge of the steps at which control of gene expression in eukaryotic cells occurs.

    Learning Outcomes

    (LO1) To evaluate current knowledge and understanding of how and where expression in eukaryotes is regulated

    (LO2) To critically discuss the role and regulation of RNA synthesis, processing, stability and transport

    (LO3) To compare and contrast model developmental systems such as plant flowering and early embryonic development in Drosophila

    (LO4) To synthesise information, critically review evidence to support conclusions, and define complex genetic problems by applying appropriate knowledge and skills

    (S1) Improving own learning/performance - Self-awareness/self-analysis

  • Drug Metabolism and Drug Response (LIFE315)
    Level3
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting80:20
    Aims

    To demonstrate the relevance and importance of the principles of drug metabolism and pharmacokinetics To explain the importance of the relationship between drug disposition and drug response To develop in students the ability to apply, critically evaluate and interpret this knowledge and understanding, to solve complex problems in pharmacology

    Learning Outcomes

    (LO1) To appraise the principles of drug disposition and drug response, particularly in relation to why subjects differ in their response to drugs

    (LO2) To critically discuss the relevance of basic pharmacokinetic principles to achieving a good response to therapy

    (LO3) To critically analyse pharmacokinetic data

    (LO4) To evaluate the dispositional basis of adverse drug reactions

    (LO5) To critically discuss the relevant physicochemical characteristics of nanomaterials that relate to their interactions with biological systems.

    (S1) Problem solving skills

    (S2) Teamwork

    (S3) Written Communication Skills

Programme Year Four

Students can transfer into the C900 (MBiolSci) programme to complete a four-year integrated master’s (subject to performance). This offers 6-week internships and one-year placement opportunities in the UK or abroad (subject to availability).

The programme detail and modules listed are illustrative only and subject to change.


Teaching and Learning

You will experience a range of learning environments during your studies at Liverpool. These will include student-centred activities as well as lectures, tutorials, laboratory practicals, dissection classes, fieldwork, data handling sessions and computer workshops. Some of these activities will be performed individually, such as personal research projects, and others in small tutorial or project groups, in addition to formal lectures and workshops. You will have research staff as well as your own academic adviser for individual tuition on our acclaimed tutorial programme.


Assessment

As well as factual knowledge and understanding, biologists need practical and organisational skills, and an ability to work both alone and with other people. We record development of these abilities through continuous assessment during each semester and by final examination.