Connective tissue protein turnover

Howard Choi, Deborah Simpson, Ding Wang, Mark Prescott, Andrew A Pitsillides, Jayesh Dudhia, Peter D Clegg, Peipei Ping, Chavaunne T Thorpe (2020) Heterogeneity of proteome dynamics between connective tissue phases of adult tendon. [
PDF] [PUBMED] [DOI] [Abstract...]

Improving the quality of turnover measurement

Stephen W. Holman, Dean E. Hammond, Deborah M. Simpson, John Waters, Jane L. Hurst and Robert J. Beynon (2016) Protein turnover measurement using selected reaction monitoring-mass spectrometry (SRM MS). [PUBMED] [PDF] [Abstract...]

Proteome dynamics in a non-model species - the challenges!

Hammond DE, Claydon AJ, Simpson DM, Edward D, Stockley P, Hurst JL, Beynon RJ. (2016) Proteome Dynamics: Tissue Variation in the Kinetics of Proteostasis in Intact Animals. [PUBMED] [PDF] [Abstract...]

Dynamic sperm labelling

Claydon AJ, Ramm SA, Pennington A, Hurst JL, Stockley P, Beynon R. (2012) Heterogenous turnover of sperm and seminal vesicle proteins in the mouse revealed by dynamic metabolic labeling. [PUBMED][PDF] [Abstract...]

Whole animal protein turnover studies

Claydon, A.J., Thom, M.D., Hurst, J.L. & Beynon, R.J. (2011) Protein turnover: measurement of proteome dynamics by whole animal metabolic labelling with stable isotope labelled amino acids. Proteomics 12:1194-1206 [PUBMED][PDF] [Abstract...]