Dr Riaz Akhtar MEng, PhD, SFHEA, FIMMM
Senior Lecturer in Biomedical Engineering Mechanical, Materials & Aerospace Eng
- Work email R.Akhtar@liverpool.ac.uk
- Personal WebsiteResearch Group website
Publications
Selected Publications
- Localised micro- and nano-scale remodelling in the diabetic aorta (Journal article - 2014)
- Nanoscale characterization of the biomechanical properties of collagen fibrils in the sclera (Journal article - 2014)
- In vitro characterisation of arterial stiffening: From the macro- to the nano-scale (Journal article - 2014)
- Characterizing the elastic properties of tissues (Journal article - 2011)
- Morphological and histological adaptation of muscle and bone to loading induced by repetitive activation of muscle (Journal article - 2014)
- Bicuspid valve aortopathy is associated with distinct patterns of matrix degradation (Journal article - 2019)
2021
Exploring the potential of rapid evaporative ionization mass spectrometry (Intelligent Knife) for point-of-care testing in aortic surgery (Journal article)
Davies, H. A., Caamano-Gutierrez, E., Sarsby, J., Nawaytou, O., Harky, A., Akhtar, R., . . . Madine, J. (n.d.). Exploring the potential of rapid evaporative ionization mass spectrometry (Intelligent Knife) for point-of-care testing in aortic surgery. European Journal of Cardio-Thoracic Surgery. doi:10.1093/ejcts/ezab166
Nano-Scale Stiffness and Collagen Fibril Deterioration: Probing the Cornea Following Enzymatic Degradation Using Peakforce-QNM AFM (Journal article)
Kazaili, A., Abdul-Amir Al-Hindy, H., Madine, J., & Akhtar, R. (n.d.). Nano-Scale Stiffness and Collagen Fibril Deterioration: Probing the Cornea Following Enzymatic Degradation Using Peakforce-QNM AFM. Sensors, 21(5), 1629. doi:10.3390/s21051629
Influence of Prednisolone and Alendronate on the de novo Mineralization of Zebrafish Caudal Fin (Journal article)
Bohns, F. R., Shih, Y., Chuang, Y., Akhtar, R., & Chen, P. (n.d.). Influence of Prednisolone and Alendronate on the de novo Mineralization of Zebrafish Caudal Fin. JBMR Plus. doi:10.1002/jbm4.10435
2020
Investigation of fibrillin microfibrils in the canine cruciate ligament in dogs with different predispositions to ligament rupture (Journal article)
Cox, T., Comerford, E. J., Wegg, M., Mills, A., Barrett, S. D., Smith, K. D., . . . Akhtar, R. (2020). Investigation of fibrillin microfibrils in the canine cruciate ligament in dogs with different predispositions to ligament rupture. Research in Veterinary Science, 133, 53-58. doi:10.1016/j.rvsc.2020.09.006
Eye bank versus surgeon prepared DMEK tissues: influence on adhesion and re-bubbling rate. (Journal article)
Romano, V., Kazaili, A., Pagano, L., Gadhvi, K. A., Titley, M., Steger, B., . . . Parekh, M. (2020). Eye bank versus surgeon prepared DMEK tissues: influence on adhesion and re-bubbling rate.. The British journal of ophthalmology. doi:10.1136/bjophthalmol-2020-317608
The systemic influence of chronic smoking on skin structure and mechanical function (Journal article)
Langton, A. K., Tsoureli-Nikita, E., Merrick, H., Zhao, X., Antoniou, C., Stratigos, A., . . . Griffiths, C. E. M. (2020). The systemic influence of chronic smoking on skin structure and mechanical function. JOURNAL OF PATHOLOGY, 251(4), 420-428. doi:10.1002/path.5476
Inflation Experiments and Inverse Finite Element Modelling of Posterior Human Sclera (Journal article)
Geraghty, B., Abass, A. M. F. F., Eliasy, A., Jones, S., Rama, P., Kassem, W., . . . Elsheikh, A. (2020). Inflation Experiments and Inverse Finite Element Modelling of Posterior Human Sclera. Journal of Biomechanics, 98. doi:10.1016/j.jbiomech.2019.109438
2019
Microscale assessment of corneal viscoelastic properties under physiological pressures (Journal article)
Kazaili, A., Geraghty, B., & Akhtar, R. (2019). Microscale assessment of corneal viscoelastic properties under physiological pressures. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 100. doi:10.1016/j.jmbbm.2019.103375
Biochemical Characteristics of the Aortic True Lumen Wall, False Lumen Wall and Flap During the Acute Phases of Type A Aortic Dissection in Humans (Conference Paper)
Harky, A., Chim, Y. H., Davies, H. A., Field, M., Nawaytou, O., Akhtar, R., & Madine, J. (2019). Biochemical Characteristics of the Aortic True Lumen Wall, False Lumen Wall and Flap During the Acute Phases of Type A Aortic Dissection in Humans. In CIRCULATION Vol. 140. Retrieved from http://gateway.webofknowledge.com/
Bicuspid valve aortopathy is associated with distinct patterns of matrix degradation (Journal article)
Chim, Y. H., Davies, H., Mason, D., Nawaytou, O., Field, M., Madine, J., & Akhtar, R. (2019). Bicuspid valve aortopathy is associated with distinct patterns of matrix degradation. The Journal of Thoracic and Cardiovascular Surgery, 160(6), E239-E257. doi:10.1016/j.jtcvs.2019.08.094
Idiopathic degenerative thoracic aneurysms are associated with increased aortic medial amyloid (Journal article)
Davies, H. A., Caamano-Gutierrez, E., Chim, Y. H., Field, M., Nawaytou, O., Ressel, L., . . . Madine, J. (n.d.). Idiopathic degenerative thoracic aneurysms are associated with increased aortic medial amyloid. Amyloid: international journal of experimental and clinical investigation, 26(3), 148-155. doi:10.1080/13506129.2019.1625323
The effect of corneal cross-linking on biomechanical properties in human eye-banked corneas using nano-indentation microscopy (Conference Paper)
Alenezi, B., Hillarby, C., Kazaili, A., Akhtar, R., & Radhakrishnan, H. (2019). The effect of corneal cross-linking on biomechanical properties in human eye-banked corneas using nano-indentation microscopy. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 60. Retrieved from http://gateway.webofknowledge.com/
Macro- and Micro-mechanical Properties of the Ovine Aorta: Correlation with Regional Variations in Collagen, Elastin and Glycosominoglycan Levels (Journal article)
Panpho, P., Brendan, G., Chim, Y. H., Davies, H., Field, M., Madine, J., & Akhtar, R. (n.d.). Macro- and Micro-mechanical Properties of the Ovine Aorta: Correlation with Regional Variations in Collagen, Elastin and Glycosominoglycan Levels. Artery Research, 25(1-2), 27-36. doi:10.2991/artres.k.191114.003
Quality of Reporting in Human Aortic Tissue Research – A Systematic Review (Journal article)
Chim, Y. -H., Caamaño-Gutiérrez, E., Birla, R., Madine, J., Field, M., Akhtar, R., & Davies, H. A. (n.d.). Quality of Reporting in Human Aortic Tissue Research – A Systematic Review. Artery Research. doi:10.2991/artres.k.191106.003
Line-Field Optical Coherence Tomography as a tool for In vitro characterization of corneal biomechanics under physiological pressures (Journal article)
Kazaili, A., Lawman, S., Geraghty, B., Eliasy, A., Zheng, Y., Shen, Y., & Akhtar, R. (2019). Line-Field Optical Coherence Tomography as a tool for In vitro characterization of corneal biomechanics under physiological pressures. Scientific Reports. doi:10.1038/s41598-019-42789-4
Carbon spheres as lubricant additives for improving tribological performance of polyetheretherketone (Journal article)
Wu, C., Wei, C., Jin, X., Akhtar, R., & Zhang, W. (2019). Carbon spheres as lubricant additives for improving tribological performance of polyetheretherketone. JOURNAL OF MATERIALS SCIENCE, 54(6), 5127-5135. doi:10.1007/s10853-018-3177-4
2018
An investigation into the impact of warm mix asphalt additives on asphalt mixture phases through a nano-mechanical approach (Journal article)
Abd, D. M., Al-Khalid, H., & Akhtar, R. (2018). An investigation into the impact of warm mix asphalt additives on asphalt mixture phases through a nano-mechanical approach. CONSTRUCTION AND BUILDING MATERIALS, 189, 296-306. doi:10.1016/j.conbuildmat.2018.08.165
Adhesion properties of warm-modified bituminous binders (WMBBs) determined using pull-off tests and atomic force microscopy (Journal article)
Abd, D. M., Al-Khalid, H., & Akhtar, R. (2018). Adhesion properties of warm-modified bituminous binders (WMBBs) determined using pull-off tests and atomic force microscopy. ROAD MATERIALS AND PAVEMENT DESIGN, 19(8), 1926-1939. doi:10.1080/14680629.2017.1374993
AFM Characterization of the Internal Mammary Artery as a Novel Target for Arterial Stiffening (Journal article)
Chang, Z., Paoletti, P., Hansen, M. L., Beck, H. C., Chen, P. -Y., Rasmussen, L. M., & Akhtar, R. (2018). AFM Characterization of the Internal Mammary Artery as a Novel Target for Arterial Stiffening. SCANNING. doi:10.1155/2018/6340425
Structure, mechanical properties and surface morphology of the snapping shrimp claw (Journal article)
Qian, Z., Yang, M., Zhou, L., Liu, J., Akhtar, R., Liu, C., . . . Ren, L. (2018). Structure, mechanical properties and surface morphology of the snapping shrimp claw. JOURNAL OF MATERIALS SCIENCE, 53(15), 10666-10678. doi:10.1007/s10853-018-2364-7
Zebrafish as a model to study bone maturation: Nanoscale structural and mechanical characterization of age-related changes in the zebrafish vertebral column (Journal article)
Chang, Z., Chen, P. -Y., Chuang, Y. -J., & Akhtar, R. (2018). Zebrafish as a model to study bone maturation: Nanoscale structural and mechanical characterization of age-related changes in the zebrafish vertebral column. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 84, 54-63. doi:10.1016/j.jmbbm.2018.05.004
Nanomechanics and ultrastructure of the internal mammary artery adventitia in patients with low and high pulse wave velocity (Journal article)
Chang, Z., Paoletti, P., Barrett, S. D., Chim, Y. H., Caamano-Gutierrez, E., Hansen, M. L., . . . Akhtar, R. (2018). Nanomechanics and ultrastructure of the internal mammary artery adventitia in patients with low and high pulse wave velocity. ACTA BIOMATERIALIA, 73, 437-448. doi:10.1016/j.actbio.2018.04.036
The optimization and production of stable homogeneous amine enriched surfaces with characterized nanotopographical properties for enhanced osteoinduction of mesenchymal stem cells (Journal article)
Chen, R., Hunt, J. A., Fawcett, S., D'Sa, R., Akhtar, R., & Curran, J. M. (2018). The optimization and production of stable homogeneous amine enriched surfaces with characterized nanotopographical properties for enhanced osteoinduction of mesenchymal stem cells. Journal of Biomedical Materials Research Part A, 106(7), 1862-1877. doi:10.1002/jbm.a.36383
Facile production of nanocomposites of carbon nanotubes and polycaprolactone with high aspect ratios with potential applications in drug delivery (Journal article)
Niezabitowska, E., Smith, J., Prestly, M. R., Akhtar, R., von Aulock, F. W., Lavallee, Y., . . . McDonald, T. O. (2018). Facile production of nanocomposites of carbon nanotubes and polycaprolactone with high aspect ratios with potential applications in drug delivery. RSC ADVANCES, 8(30), 16444-16454. doi:10.1039/c7ra13553j
Novel Methodology to Investigate and Obtain a Complete Blend between RAP and Virgin Materials (Journal article)
Abd, D. M., Al-Khalid, H., & Akhtar, R. (2018). Novel Methodology to Investigate and Obtain a Complete Blend between RAP and Virgin Materials. JOURNAL OF MATERIALS IN CIVIL ENGINEERING, 30(5). doi:10.1061/(ASCE)MT.1943-5533.0002230
Oscillatory nanoindentation of highly compliant hydrogels: A critical comparative analysis with rheometry (Journal article)
Akhtar, R., Draper, E. R., Adams, D., & Hay, J. (2018). Oscillatory nanoindentation of highly compliant hydrogels: A critical comparative analysis with rheometry. Journal of Materials Research, 33(8), 873-883. doi:10.1557/jmr.2018.62
The effect of ageing and osteoarthritis on the mechanical properties of cartilage and bone in the human knee joint (Journal article)
Peters, A., Akhtar, R., Comerford, E., & Bates, K. (2018). The effect of ageing and osteoarthritis on the mechanical properties of cartilage and bone in the human knee joint. Scientific Reports, 8. doi:10.1038/s41598-018-24258-6
Tissue material properties and computational modelling of the human tibiofemoral joint: a critical review (Journal article)
Peters, A. E., Akhtar, R., Comerford, E. J., & Bates, K. T. (2018). Tissue material properties and computational modelling of the human tibiofemoral joint: a critical review. PEERJ, 6. doi:10.7717/peerj.4298
2017
Implication of Free Fatty Acids in Thrombin Generation and Fibrinolysis in Vascular Inflammation in Zucker Rats and Evolution with Aging (Journal article)
Lagrange, J., Didelot, M., Mohamadi, A., Walton, L. A., Bloemen, S., de laat, B., . . . Regnault, V. (2017). Implication of Free Fatty Acids in Thrombin Generation and Fibrinolysis in Vascular Inflammation in Zucker Rats and Evolution with Aging. FRONTIERS IN PHYSIOLOGY, 8. doi:10.3389/fphys.2017.00949
Drying Affects the Fiber Network in Low Molecular Weight Hydrogels (Journal article)
Mears, L. L. E., Draper, E. R., Castilla, A. M., Su, H., Zhuola., Dietrich, B., . . . Adams, D. J. (2017). Drying Affects the Fiber Network in Low Molecular Weight Hydrogels. BIOMACROMOLECULES, 18(11), 3531-3540. doi:10.1021/acs.biomac.7b00823
The role of subcutaneous tissue stiffness on microneedle performance in a representative in vitro model of skin. (Journal article)
Moronkeji, K., Todd, S., Dawidowska, I., Barrett, S. D., & Akhtar, R. (2017). The role of subcutaneous tissue stiffness on microneedle performance in a representative in vitro model of skin. JOURNAL OF CONTROLLED RELEASE, 265, 102-112. doi:10.1016/j.jconrel.2016.11.004
Nano-structure and mechanical changes in sclera following proteoglycan depletion (Conference Paper)
Zhuola, L., Kharaz, Y., Comerford, E., & Akhtar, R. (2017). Nano-structure and mechanical changes in sclera following proteoglycan depletion. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 98 (pp. A11). Retrieved from http://gateway.webofknowledge.com/
Dual-stimuli responsive injectable nanogel/solid drug nanoparticle nanocomposites for release of poorly soluble drugs (Conference Paper)
Town, A., Gurjar, R., Giardiello, M., Briggs, M., Akhtar, R., Siccardi, M., & McDonald, T. (2017). Dual-stimuli responsive injectable nanogel/solid drug nanoparticle nanocomposites for release of poorly soluble drugs. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 254. doi:10.1039/C6NR07858C
The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry (Journal article)
Kearns, V. R., Tasker, J., Zhuola., Akhtar, R., Bachhuka, A., Vasilev, K., . . . Williams, R. (2017). The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry. Journal of Materials Science: Materials in Medicine, 28. doi:10.1007/s10856-017-5926-3
Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy (Journal article)
Weli, H. K., Akhtar, R., Chang, Z., Li, W. -W., Cooper, J., & Yang, Y. (2017). Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy. EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 214, 78-85. doi:10.1016/j.ejogrb.2017.04.037
Micromechanical properties of canine femoral articular cartilage following multiple freeze-thaw cycles (Journal article)
Peters, A. E., Comerford, E. J., Macaulay, S., Bates, K. T., & Akhtar, R. (2017). Micromechanical properties of canine femoral articular cartilage following multiple freeze-thaw cycles. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 71, 114-121. doi:10.1016/j.jmbbm.2017.03.006
Low cost and renewable sulfur-polymers by inverse vulcanisation, and their potential for mercury capture (Journal article)
Parker, D. J., Jones, H. A., Petcher, S., Cervini, L., Griffin, J. M., Akhtar, R., & Hasell, T. (2017). Low cost and renewable sulfur-polymers by inverse vulcanisation, and their potential for mercury capture. JOURNAL OF MATERIALS CHEMISTRY A, 5(23), 11682-11692. doi:10.1039/c6ta09862b
Ultrastructural and nanomechanical changes of the cornea following in-vitro enzymatic treatment (Conference Paper)
Kazaili, A., & Akhtar, R. (2017). Ultrastructural and nanomechanical changes of the cornea following in-vitro enzymatic treatment. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 98 (pp. A12). Retrieved from http://gateway.webofknowledge.com/
Dual-stimuli responsive injectable microgel/solid drug nanoparticle nanocomposites for release of poorly soluble drugs (Journal article)
Town, A. R., Giardiello, M., Gurjar, R., Siccardi, M., Briggs, M. E., Akhtar, R., & McDonald, T. O. (2017). Dual-stimuli responsive injectable microgel/solid drug nanoparticle nanocomposites for release of poorly soluble drugs. Nanoscale, 9(19), 6302-6314. doi:10.1039/c6nr07858c
Nano-scale properties of warm-modified bituminous binders determined with atomic force microscopy (Journal article)
Abd, D. M., Al-Khalid, H., & Akhtar, R. (2017). Nano-scale properties of warm-modified bituminous binders determined with atomic force microscopy. ROAD MATERIALS AND PAVEMENT DESIGN, 18, 189-202. doi:10.1080/14680629.2017.1304262
Nanoindentation and the Low Velocity Impact Response of Biofibre, Biopolymer and its Biocomposite Derived from Sugar Palm Tree (Journal article)
Sahari, J., Sapuan, S. M., Zainudin, E. S., Ishak, M. R., Maleque, M. A., Zuhri, M. Y. M., & Akhtar, R. (2017). Nanoindentation and the Low Velocity Impact Response of Biofibre, Biopolymer and its Biocomposite Derived from Sugar Palm Tree. CURRENT ORGANIC SYNTHESIS, 14(2), 227-232. doi:10.2174/1570179413666160831122841
Microencapsulated Phase Change Materials in Solar-Thermal Conversion Systems: Understanding Geometry-Dependent Heating Efficiency and System Reliability (Journal article)
Zheng, Z., Chang, Z., Xu, G. -K., McBride, F., Ho, A., Zhuola, Z., . . . Shchukin, D. (2017). Microencapsulated Phase Change Materials in Solar-Thermal Conversion Systems: Understanding Geometry-Dependent Heating Efficiency and System Reliability. ACS Nano, 11(1), 721-729. doi:10.1021/acsnano.6b07126
2016
Frequency-modulated atomic force microscopy localises viscoelastic remodelling in the ageing sheep aorta (Journal article)
Akhtar, R., Graham, H. K., Derby, B., Sherratt, M. J., Trafford, A. W., Chadwick, R. S., & Gavara, N. (2016). Frequency-modulated atomic force microscopy localises viscoelastic remodelling in the ageing sheep aorta. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 64, 10-17. doi:10.1016/j.jmbbm.2016.07.018
The effect of multiple freeze-thaw cycles on canine femoral articular cartilage (Conference Paper)
Peters, A. E., Comerford, E. J., Macaulay, S., Bates, K. T., & Akhtar, R. (2016). The effect of multiple freeze-thaw cycles on canine femoral articular cartilage. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 97 (pp. A13). Retrieved from http://gateway.webofknowledge.com/
Reversible Photoreduction as a Trigger for Photoresponsive Gels (Journal article)
Draper, E. R., Schweins, R., Akhtar, R., Groves, P., Chechik, V., Zwijnenburg, M. A., & Adams, D. J. (2016). Reversible Photoreduction as a Trigger for Photoresponsive Gels. CHEMISTRY OF MATERIALS, 28(17), 6336-6341. doi:10.1021/acs.chemmater.6b02677
Biomechanical Changes of Collagen Cross-Linking on Human Keratoconic Corneas Using Scanning Acoustic Microscopy (Journal article)
Beshtawi, I. M., Akhtar, R., Hillarby, M. C., O'Donnell, C., Zhao, X., Brahma, A., . . . Radhakrishnan, H. (2016). Biomechanical Changes of Collagen Cross-Linking on Human Keratoconic Corneas Using Scanning Acoustic Microscopy. CURRENT EYE RESEARCH, 41(5), 609-615. doi:10.3109/02713683.2015.1042545
A pilot study of scanning acoustic microscopy as a tool for measuring arterial stiffness in aortic biopsies (Journal article)
Akhtar, R., Cruickshank, J. K., Zhao, X., Derby, B., & Weber, T. (2016). A pilot study of scanning acoustic microscopy as a tool for measuring arterial stiffness in aortic biopsies. ARTERY RESEARCH, 13, 1-5. doi:10.1016/j.artres.2015.11.001
Chapter 4. Natural Fibre-reinforced Thermoplastic Starch Composites (Chapter)
Sahari, J., Sapuan, S. M., El-Shekeil, Y. A., Ishak, M. R., & Akhtar, R. (2015). Chapter 4. Natural Fibre-reinforced Thermoplastic Starch Composites. In Green Chemistry Series (pp. 109-142). Royal Society of Chemistry. doi:10.1039/9781782622796-00109
Complex Shear Modulus of Hydrogels Using a Dynamic Nanoindentation Method (Conference Paper)
Akhtar, R., Draper, E. R., Adams, D. J., & Pfaff, H. (2016). Complex Shear Modulus of Hydrogels Using a Dynamic Nanoindentation Method. In MECHANICS OF BIOLOGICAL SYSTEMS AND MATER IALS, VOL 6 (pp. 141-145). doi:10.1007/978-3-319-21455-9_17
In Vitro Quantification of Optimal Impact Properties for Microneedle Penetration (Conference Paper)
Moronkeji, K., Todd, S., Dawidowska, I., & Akhtar, R. (2016). In Vitro Quantification of Optimal Impact Properties for Microneedle Penetration. In MECHANICS OF BIOLOGICAL SYSTEMS AND MATER IALS, VOL 6 (pp. 39-49). doi:10.1007/978-3-319-21455-9_5
Mechanics of Biological Systems and Materials, Volume 6 (Chapter)
Mechanics of Biological Systems and Materials, Volume 6 (2016). Springer International Publishing. doi:10.1007/978-3-319-21455-9
Molecular Cues Guiding Matrix Stiffness in Liver Fibrosis (Journal article)
Saneyasu, T., Akhtar, R., & Sakai, T. (2016). Molecular Cues Guiding Matrix Stiffness in Liver Fibrosis. BIOMED RESEARCH INTERNATIONAL, 2016. doi:10.1155/2016/2646212
Molecular Mechanism Responsible for Fibronectin-controlled Alterations in Matrix Stiffness in Advanced Chronic Liver Fibrogenesis (Journal article)
Iwasaki, A., Sakai, K., Moriya, K., Sasaki, T., Keene, D. R., Akhtar, R., . . . Sakai, T. (2016). Molecular Mechanism Responsible for Fibronectin-controlled Alterations in Matrix Stiffness in Advanced Chronic Liver Fibrogenesis. The Journal of biological chemistry, 291(1), 72-88. doi:10.1074/jbc.M115.691519
2015
Using intermolecular interactions to crosslink PIM- 1 and modify its gas sorption properties (Journal article)
McDonald, T., Akhtar, R., Hon Lau, C., Ratvijitvech, T., Cheng, G., Clowes, R., . . . Cooper, A. (2015). Using intermolecular interactions to crosslink PIM-1 and modify its gas sorption properties. Journal of Materials Chemistry A, 3(9), 4855-4864. doi:10.1039/c4ta06070a
Quantitative Nanomechanical Properties of the Cuticle of the Multicolored Asian Lady Beetle Using the Modulus Mapping Technique (Journal article)
Sun, J., Wu, W., Xue, W., Akhtar, R., Ren, L., & Tong, J. (2015). Quantitative Nanomechanical Properties of the Cuticle of the Multicolored Asian Lady Beetle Using the Modulus Mapping Technique. CURRENT NANOSCIENCE, 11(2), 245-252. doi:10.2174/1573413711666141223224759
Age-Related Variation in the Biomechanical and Structural Properties of the Corneo-Scleral Tunic (Chapter)
Geraghty, B., Whitford, C., Boote, C., Akhtar, R., & Elsheikh, A. (2015). Age-Related Variation in the Biomechanical and Structural Properties of the Corneo-Scleral Tunic. In Engineering Materials and Processes (pp. 207-235). Springer International Publishing. doi:10.1007/978-3-319-03970-1_9
Introduction: Aging and the Mechanical Properties of Tissues (Chapter)
Akhtar, R., & Derby, B. (2015). Introduction: Aging and the Mechanical Properties of Tissues. In Engineering Materials and Processes (pp. 1-6). Springer International Publishing. doi:10.1007/978-3-319-03970-1_1
Mechanical Properties of Aging Human Skin (Chapter)
Moronkeji, K., & Akhtar, R. (2015). Mechanical Properties of Aging Human Skin. In Engineering Materials and Processes (pp. 237-263). Springer International Publishing. doi:10.1007/978-3-319-03970-1_10
Mechanical Properties of Aging Soft Tissues (Book)
Mechanical Properties of Aging Soft Tissues (2015). . Springer International Publishing. doi:10.1007/978-3-319-03970-1
P1.2 NANOMECHANICAL ALTERATIONS IN THE ADVENTITIAL LAYER OF THE INTERNAL MAMMARY ARTERY OF PATIENTS WITH HIGH PWV (Journal article)
Chang, Z., Hansen, M. L., Rasmussen, L. M., & Akhtar*, R. (n.d.). P1.2 NANOMECHANICAL ALTERATIONS IN THE ADVENTITIAL LAYER OF THE INTERNAL MAMMARY ARTERY OF PATIENTS WITH HIGH PWV. Artery Research, 12(C), 3. doi:10.1016/j.artres.2015.10.196
Using the hydrolysis of anhydrides to control gel properties and homogeneity in pH-triggered gelation (Journal article)
Draper, E. R., Mears, L. L. E., Castilla, A. M., King, S. M., McDonald, T. O., Akhtar, R., & Adams, D. J. (2015). Using the hydrolysis of anhydrides to control gel properties and homogeneity in pH-triggered gelation. RSC ADVANCES, 5(115), 95369-95378. doi:10.1039/c5ra22253b
2014
Morphological and histological adaptation of muscle and bone to loading induced by repetitive activation of muscle (Journal article)
Vickerton, P., Jarvis, J. C., Gallagher, J. A., Akhtar, R., Sunderland, H., & Jeffery, N. (2014). Morphological and histological adaptation of muscle and bone to loading induced by repetitive activation of muscle. Proceedings of the Royal Society B: Biological Sciences, 281(1788). doi:10.1098/rspb.2014.0786
Biomechanical Stiffness Changes of Collagen Crosslinking on Human Keratoconic Corneas using Scanning Acoustic Microscopy (Conference Paper)
Beshtawi, I. M., Akhtar, R., Hillarby, C., Clare, O., Zhao, X., Brahma, A., . . . Cross-Linking, C. (2014). Biomechanical Stiffness Changes of Collagen Crosslinking on Human Keratoconic Corneas using Scanning Acoustic Microscopy. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 55. Retrieved from http://gateway.webofknowledge.com/
Nanoscale characterization of the biomechanical properties of collagen fibrils in the sclera (vol 104, 103703, 2004) (Journal article)
Papi, M., Paoletti, P., Geraghty, B., & Akhtar, R. (2014). Nanoscale characterization of the biomechanical properties of collagen fibrils in the sclera (vol 104, 103703, 2004). APPLIED PHYSICS LETTERS, 104(12). doi:10.1063/1.4869960
Biomechanical Changes After Repeated Collagen Cross-Linking on Human Corneas Assessed In Vitro Using Scanning Acoustic Microscopy (Journal article)
Beshtawi, I. M., Akhtar, R., Hillarby, M. C., O'Donnell, C., Zhao, X., Brahma, A., . . . Radhakrishnan, H. (2014). Biomechanical Changes After Repeated Collagen Cross-Linking on Human Corneas Assessed In Vitro Using Scanning Acoustic Microscopy. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 55(3), 1549-1554. doi:10.1167/iovs.13-13042
Nanoscale characterization of the biomechanical properties of collagen fibrils in the sclera (Journal article)
Papi, M., Paoletti, P., Geraghty, B., & Akhtar, R. (2014). Nanoscale characterization of the biomechanical properties of collagen fibrils in the sclera. APPLIED PHYSICS LETTERS, 104(10). doi:10.1063/1.4868388
In vitro characterisation of arterial stiffening: From the macro- to the nano-scale (Journal article)
Akhtar, R. (n.d.). In vitro characterisation of arterial stiffening: From the macro- to the nano-scale. Artery Research, 8(1), 1. doi:10.1016/j.artres.2014.01.002
Localised micro- and nano-scale remodelling in the diabetic aorta (Journal article)
Akhtar, R., Cruickshank, J. K., Zhao, X., Walton, L. A., Gardiner, N. J., Barrett, S. D., . . . Sherratt, M. J. (2014). Localised micro- and nano-scale remodelling in the diabetic aorta. Acta Biomaterialia, 10(11), 4843-4851. doi:10.1016/j.actbio.2014.07.001
Scanning acoustic microscopy of biological cryosections: the effect of local thickness on apparent acoustic wave speed (Journal article)
Williams, C. J., Graham, H. K., Zhao, X., Akhtar, R., Griffiths, C. E. M., Watson, R. E. B., . . . Derby, B. (2014). Scanning acoustic microscopy of biological cryosections: the effect of local thickness on apparent acoustic wave speed. MRS Proceedings, 1621, 143-148. doi:10.1557/opl.2014.283
2013
Biomechanical Properties of Human Corneas Following Low- and High-Intensity Collagen Cross-Linking Determined With Scanning Acoustic Microscopy (Journal article)
Beshtawi, I. M., Akhtar, R., Hillarby, M. C., O'Donnell, C., Zhao, X., Brahma, A., . . . Radhakrishnan, H. (2013). Biomechanical Properties of Human Corneas Following Low- and High-Intensity Collagen Cross-Linking Determined With Scanning Acoustic Microscopy. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 54(8), 5273-5280. doi:10.1167/iovs.13-12576
Biomechanical changes in Human Corneas after Low and High Intensity Collagen Cross-Linking Treatment measured using Scanning Acoustic Microscopy (Conference Paper)
Beshtawi, I., Akhtar, R., Hillarby, C., O'Donnell, C., Zhao, X., Brahma, A., . . . Res, E. V. S. (2013). Biomechanical changes in Human Corneas after Low and High Intensity Collagen Cross-Linking Treatment measured using Scanning Acoustic Microscopy. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 54. Retrieved from http://gateway.webofknowledge.com/
Scanning Acoustic Microscopy for Mapping the Microelastic Properties of Human Corneal Tissue (Journal article)
Beshtawi, I. M., Akhtar, R., Hillarby, M. C., O'Donnell, C., Zhao, X., Brahma, A., . . . Radhakrishnan, H. (2013). Scanning Acoustic Microscopy for Mapping the Microelastic Properties of Human Corneal Tissue. CURRENT EYE RESEARCH, 38(4), 437-444. doi:10.3109/02713683.2012.753094
IFSS, TG, FT-IR spectra of impregnated sugar palm (Arenga pinnata) fibres and mechanical properties of their composites (Journal article)
Ishak, M. R., Leman, Z., Salit, M. S., Abd Rahman, M. Z., Uyup, M. K. A., & Akhtar, R. (2013). IFSS, TG, FT-IR spectra of impregnated sugar palm (Arenga pinnata) fibres and mechanical properties of their composites. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 111(2), 1375-1383. doi:10.1007/s10973-012-2457-5
ARTERIAL STIFFENING ACROSS MULTIPLE LENGTH SCALES (Journal article)
Akhtar, R. (n.d.). ARTERIAL STIFFENING ACROSS MULTIPLE LENGTH SCALES. Artery Research, 7(3-4), 109. doi:10.1016/j.artres.2013.10.383
2012
Nanomechanical properties of dental resin-composites (Journal article)
El-Safty, S., Akhtar, R., Silikas, N., & Watts, D. C. (2012). Nanomechanical properties of dental resin-composites. DENTAL MATERIALS, 28(12), 1292-1300. doi:10.1016/j.dental.2012.09.007
Nanoindentation creep versus bulk compressive creep of dental resin-composites (Journal article)
El-Safty, S., Silikas, N., Akhtar, R., & Watts, D. C. (2012). Nanoindentation creep versus bulk compressive creep of dental resin-composites. Dental Materials, 28(11), 1171-1182. doi:10.1016/j.dental.2012.08.012
Nanoindentation creep versus bulk compressive creep of dental resin-composites (Journal article)
El-Saftya, S., Silikas, N., Akhtar, R., & Watts, D. C. (2012). Nanoindentation creep versus bulk compressive creep of dental resin-composites. DENTAL MATERIALS, 28(11), 71-82. doi:10.1016/j.dental.2012.08.012
Cardiotrophin 1 Is Involved in Cardiac, Vascular, and Renal Fibrosis and Dysfunction (Journal article)
Lopez-Andres, N., Rousseau, A., Akhtar, R., Calvier, L., Inigo, C., Labat, C., . . . Rossignol, P. (2012). Cardiotrophin 1 Is Involved in Cardiac, Vascular, and Renal Fibrosis and Dysfunction. HYPERTENSION, 60(2), 563-+. doi:10.1161/HYPERTENSIONAHA.112.194407
Multi-Layer Phase Analysis: Quantifying the Elastic Properties of Soft Tissues and Live Cells with Ultra-High-Frequency Scanning Acoustic Microscopy (Journal article)
Zhao, X., Akhtar, R., Nijenhuis, N., Wilkinson, S. J., Murphy, L., Ballestrem, C., . . . Derby, B. (2012). Multi-Layer Phase Analysis: Quantifying the Elastic Properties of Soft Tissues and Live Cells with Ultra-High-Frequency Scanning Acoustic Microscopy. IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 59(4), 610-620. doi:10.1109/TUFFC.2012.2240
Cardiotrophin-1 is involved in cardiovascular and renal fibrosis and dysfunction (Conference Paper)
Lopez-Andres, N., Rousseau, A., Calvier, L., Akhtar, R., Labat, C., Cruickshank, K., . . . Rossignol, P. (2012). Cardiotrophin-1 is involved in cardiovascular and renal fibrosis and dysfunction. In CARDIOVASCULAR RESEARCH Vol. 93 (pp. S61-S62). Retrieved from http://gateway.webofknowledge.com/
Age-related variations in the biomechanical properties of human sclera (Journal article)
Geraghty, B., Jones, S. W., Rama, P., Akhtar, R., & Elsheikh, A. (2012). Age-related variations in the biomechanical properties of human sclera. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 16, 181-191. doi:10.1016/j.jmbbm.2012.10.011
2011
Quantifying micro-mechanical properties of soft biological tissues with scanning acoustic microscopy (Conference Paper)
Zhao, X., Wilkinson, S., Akhtar, R., Sherratt, M. J., Watson, R. E. B., & Derby, B. (2011). Quantifying micro-mechanical properties of soft biological tissues with scanning acoustic microscopy. In Materials Research Society Symposium Proceedings Vol. 1301 (pp. 181-186). doi:10.1557/opl.2011.572
Localised micro-mechanical stiffening in the ageing aorta (Journal article)
Graham, H. K., Akhtar, R., Kridiotis, C., Derby, B., Kundu, T., Trafford, A. W., & Sherratt, M. J. (2011). Localised micro-mechanical stiffening in the ageing aorta. MECHANISMS OF AGEING AND DEVELOPMENT, 132(10), 459-467. doi:10.1016/j.mad.2011.07.003
Lattice strains and load partitioning in bovine trabecular bone (Journal article)
Akhtar, R., Daymond, M. R., Almer, J. D., & Mummery, P. M. (2011). Lattice strains and load partitioning in bovine trabecular bone. ACTA BIOMATERIALIA, 7(2), 716-723. doi:10.1016/j.actbio.2010.10.007
Characterizing the elastic properties of tissues (Journal article)
Akhtar, R., Sherratt, M. J., Cruickshank, J. K., & Derby, B. (2011). Characterizing the elastic properties of tissues. MATERIALS TODAY, 14(3), 96-105. doi:10.1016/S1369-7021(11)70059-1
Quantifying Micro-mechanical Properties of Soft Biological Tissues with Scanning Acoustic Microscopy. (Conference Paper)
Zhao, X., Wilkinson, S., Akhtar, R., Sherratt, M. J., Watson, R. E. B., & Derby, B. (2011). Quantifying Micro-mechanical Properties of Soft Biological Tissues with Scanning Acoustic Microscopy.. In Materials Research Society symposia proceedings. Materials Research Society Vol. 1301. doi:10.1557/opl.2011.572
2010
Fibrillin microfibrils as structural biomarkers of diabetes (Conference Paper)
Akhtar, R., Cruickshank, J. K., Gardiner, N. J., Derby, B., & Sherratt, M. J. (2010). Fibrillin microfibrils as structural biomarkers of diabetes. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 91 (pp. A37). Retrieved from http://gateway.webofknowledge.com/
Localising micro-mechanical stiffening in the ageing aorta (Conference Paper)
Graham, H. K., Akhtar, R., Kridiotis, C., Derby, B., Watson, R. E. B., Trafford, A. W., & Sherratt, M. J. (2010). Localising micro-mechanical stiffening in the ageing aorta. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 91 (pp. A36). Retrieved from http://gateway.webofknowledge.com/
Mapping Micro-Mechanical and Micro-Structural Changes in the Ageing Aorta (Journal article)
Helen, G. K., Akhtar, R., Kridiotis, C., Derby, B., Trafford, A. W., & Sherratt, M. J. (2010). Mapping Micro-Mechanical and Micro-Structural Changes in the Ageing Aorta. BIOPHYSICAL JOURNAL, 98(3), 594A. doi:10.1016/j.bpj.2009.12.3234
The Effect of Type 1 Diabetes on the Structure and Function of Fibrillin Microfibrils (Conference Paper)
Akhtar, R., Cruickshank, J. K., Gardiner, N. J., Derby, B., & Sherratt, M. J. (2010). The Effect of Type 1 Diabetes on the Structure and Function of Fibrillin Microfibrils. In MRS Proceedings Vol. 1274. Springer Science and Business Media LLC. doi:10.1557/proc-1274-qq05-17
The effect of type 1 diabetes on the structure and function of fibrillin microfibrils (Conference Paper)
Akhtar, R., Cruickshank, J. K., Gardiner, N. J., Derby, B., & Sherratt, M. J. (2010). The effect of type 1 diabetes on the structure and function of fibrillin microfibrils. In Materials Research Society Symposium Proceedings Vol. 1274 (pp. 57-61). doi:10.1557/proc-1274-qq05-17
2009
Nanoindentation of histological specimens: Mapping the elastic properties of soft tissues (Journal article)
Akhtar, R., Schwarzer, N., Sherratt, M. J., Watson, R. E. B., Graham, H. K., Trafford, A. W., . . . Derby, B. (2009). Nanoindentation of histological specimens: Mapping the elastic properties of soft tissues. JOURNAL OF MATERIALS RESEARCH, 24(3), 638-646. doi:10.1557/JMR.2009.0130
Mapping the Micromechanical Properties of Cryo-sectioned Aortic Tissue with Scanning Acoustic Microscopy. (Journal article)
Akhtar, R., Sherratt, M. J., Watson, R. E. B., Kundu, T., & Derby, B. (2009). Mapping the Micromechanical Properties of Cryo-sectioned Aortic Tissue with Scanning Acoustic Microscopy.. Materials Research Society symposia proceedings. Materials Research Society, 1132E(1132-Z03-07), ukpmcpa27262. doi:10.1557/proc-1132-z03-07
2008
Effect of filler size and shape on local nanoindentation modulus of resin-composites (Journal article)
Masouras, K., Akhtar, R., Watts, D. C., & Silikas, N. (2008). Effect of filler size and shape on local nanoindentation modulus of resin-composites. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 19(12), 3561-3566. doi:10.1007/s10856-008-3520-4
Mapping the micromechanical properties of cryo-sectioned aortic tissue with Scanning Acoustic Microscopy (Conference Paper)
Akhtar, R., Sherratt, M. J., Watson, R. E. B., Kundu, T., & Derby, B. (2008). Mapping the micromechanical properties of cryo-sectioned aortic tissue with Scanning Acoustic Microscopy. In Materials Research Society Symposium Proceedings Vol. 1146 (pp. 66-71).
Mapping the micromechanical properties of cryo-sectioned aortic tissue with Scanning Acoustic Microscopy (Conference Paper)
Akhtar, R., Sherratt, M. J., Watson, R. E. B., Kundu, T., & Derby, B. (2008). Mapping the micromechanical properties of cryo-sectioned aortic tissue with Scanning Acoustic Microscopy. In Materials Research Society Symposium Proceedings Vol. 1135 (pp. 62-67).
Mapping the micromechanical properties of cryo-sectioned aortic tissue with Scanning Acoustic Microscopy (Conference Paper)
Akhtar, R., Sherratt, M. J., Watson, R. E. B., Kundu, T., & Derby, B. (2008). Mapping the micromechanical properties of cryo-sectioned aortic tissue with Scanning Acoustic Microscopy. In Materials Research Society Symposium Proceedings Vol. 1136 (pp. 53-58).
Mapping the micromechanical properties of cryo-sectioned aortic tissue with Scanning Acoustic Microscopy (Conference Paper)
Akhtar, R., Sherratt, M. J., Watson, R. E. B., Kundu, T., & Derby, B. (2008). Mapping the micromechanical properties of cryo-sectioned aortic tissue with Scanning Acoustic Microscopy. In Materials Research Society Symposium Proceedings Vol. 1133 (pp. 120-125).
Mapping the micromechanical properties of cryo-sectioned aortic tissue with scanning acoustic microscopy (Conference Paper)
Akhtar, R., Sherratt, M. J., Watson, R. E. B., Kundu, T., & Derby, B. (2008). Mapping the micromechanical properties of cryo-sectioned aortic tissue with scanning acoustic microscopy. In Materials Research Society Symposium Proceedings Vol. 1145 (pp. 195-200).
Mapping the micromechanical properties of cryo-sectioned aortic tissue with scanning acoustic microscopy (Conference Paper)
Akhtar, R., Sherratt, M. J., Watson, R. E. B., Kundu, T., & Derby, B. (2008). Mapping the micromechanical properties of cryo-sectioned aortic tissue with scanning acoustic microscopy. In Materials Research Society Symposium Proceedings Vol. 1151 (pp. 79-84).
Mapping the micromechanical properties of cryo-sectioned aortic tissue with scanning acoustic microscopy (Conference Paper)
Akhtar, R., Sherratt, M. J., Watson, R. E. B., Kundu, T., & Derby, B. (2008). Mapping the micromechanical properties of cryo-sectioned aortic tissue with scanning acoustic microscopy. In Materials Research Society Symposium Proceedings Vol. 1152 (pp. 115-120).
Elastic strains in antler trabecular bone determined by synchrotron X-ray diffraction (Journal article)
Akhtar, R., Daymond, M. R., Almer, J. D., & Mummery, P. M. (2008). Elastic strains in antler trabecular bone determined by synchrotron X-ray diffraction. ACTA BIOMATERIALIA, 4(6), 1677-1687. doi:10.1016/j.actbio.2008.05.008
In-depth hardness profiles of Stainless Steel and Ni-Ti endodontic instrument cross-sections by nano-indentation (Journal article)
Zinelis, S., Akhtar, R., Tsakiridis, P., Watts, D. C., & Silikas, N. (2008). In-depth hardness profiles of Stainless Steel and Ni-Ti endodontic instrument cross-sections by nano-indentation. INTERNATIONAL ENDODONTIC JOURNAL, 41(9), 747-754. doi:10.1111/j.1365-2591.2008.01426.x
Load transfer in bovine plexiform bone determined by synchrotron x-ray diffraction (Journal article)
Akhtar, R., Daymond, M. R., Almer, J. D., & Mummery, P. M. (2008). Load transfer in bovine plexiform bone determined by synchrotron x-ray diffraction. JOURNAL OF MATERIALS RESEARCH, 23(2), 543-550. doi:10.1557/JMR.2008.0068
Mapping the micromechanical properties of cryo-sectioned aortic tissue with scanning acoustic microscopy (Conference Paper)
Akhtar, R., Sherratt, M. J., Watson, R. E. B., Kundu, T., & Derby, B. (2008). Mapping the micromechanical properties of cryo-sectioned aortic tissue with scanning acoustic microscopy. In Materials Research Society Symposium Proceedings Vol. 1132 (pp. 41-46). doi:10.1557/proc-1132-z03-07
Nanoindentation of Histological Specimens using an Extension of the Oliver and Pharr Method (Conference Paper)
Akhtar, R., Sherratt, M. J., Bierwisch, N., Derby, B., Mummery, P. M., Watson, R. E. B., & Schwarzer, N. (2008). Nanoindentation of Histological Specimens using an Extension of the Oliver and Pharr Method. In MRS Proceedings Vol. 1097. Springer Science and Business Media LLC. doi:10.1557/proc-1097-gg01-09
2006
Microstructure-based finite element modelling and characterisation of bovine trabecular bone (Journal article)
Akhtar, R., Eichhorn, S. J., & Mummery, P. M. (2006). Microstructure-based finite element modelling and characterisation of bovine trabecular bone. Journal of Bionic Engineering, 3, 3-9.