Dr Katharine Stott MRCP MSc MRes DTM&H

Wellcome Trust Clinical PhD Fellow Molecular and Clinical Pharmacology

Publications

2019

AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial (vol 19, 649, 2018) (Journal article)

Lawrence, D. S., Youssouf, N., Molloy, S. F., Alanio, A., Alufandika, M., Boulware, D. R., . . . Jarvis, J. N. (2019). AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial (vol 19, 649, 2018). TRIALS, 20. doi:10.1186/s13063-018-3155-9

DOI: 10.1186/s13063-018-3155-9

2018

Population Pharmacokinetic Model and Meta-analysis of Outcomes of Amphotericin B Deoxycholate Use in Adults with Cryptococcal Meningitis (vol 62, e02526-17, 2018) (Journal article)

Stott, K. E., Beardsley, J., Whalley, S., Kibengo, F. M., Mai, N. T. H., Tung, N. L. N., . . . Day, J. (2018). Population Pharmacokinetic Model and Meta-analysis of Outcomes of Amphotericin B Deoxycholate Use in Adults with Cryptococcal Meningitis (vol 62, e02526-17, 2018). ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62(12). doi:10.1128/AAC.02249-18

DOI: 10.1128/AAC.02249-18

Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis (vol 62, e00885-18, 2018) (Journal article)

Stott, K. E., Beardsley, J., Kolamunnage-Dona, R., Castelazo, A. S., Kibengo, F. M., Mai, N. T. H., . . . Hope, W. (2018). Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis (vol 62, e00885-18, 2018). ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62(12). doi:10.1128/AAC.02254-18

DOI: 10.1128/AAC.02254-18

AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial (Journal article)

Lawrence, D. S., Youssouf, N., Molloy, S. L. F., Alanio, A., Alufandika, M., Boulware, D. R., . . . Jarvis, J. N. (2018). AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial. TRIALS, 19. doi:10.1186/s13063-018-3026-4

DOI: 10.1186/s13063-018-3026-4

Pharmacokinetics-pharmacodynamics of antifungal agents in the central nervous system (Journal article)

Stott, K. E., & Hope, W. (2018). Pharmacokinetics-pharmacodynamics of antifungal agents in the central nervous system. EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 14(8), 803-815. doi:10.1080/17425255.2018.1492551

DOI: 10.1080/17425255.2018.1492551

Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis (Journal article)

Stott, K. E., Beardsley, J., Kolamunnage-Dona, R., Castelazo, A. S., Kibengo, F. M., Mai, N. T. H., . . . Hope, W. (2018). Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62(9). doi:10.1128/AAC.00885-18

DOI: 10.1128/AAC.00885-18

Population Pharmacokinetic Model and Meta-analysis of Outcomes of Amphotericin B Deoxycholate Use in Adults with Cryptococcal Meningitis (Journal article)

Stott, K. E., Beardsley, J., Whalley, S., Kibengo, F. M., Mai, N. T. H., Kolamunnage-Dona, R., . . . Day, J. (2018). Population Pharmacokinetic Model and Meta-analysis of Outcomes of Amphotericin B Deoxycholate Use in Adults with Cryptococcal Meningitis. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62(7). doi:10.1128/AAC.02526-17

DOI: 10.1128/AAC.02526-17

Pharmacokinetics of rifampicin in adult TB patients and healthy volunteers: a systematic review and meta-analysis (Journal article)

Stott, K. E., Pertinez, H., Sturkenboom, M. G. G., Boeree, M. J., Aarnoutse, R., Ramachandran, G., . . . Davies, G. (2018). Pharmacokinetics of rifampicin in adult TB patients and healthy volunteers: a systematic review and meta-analysis. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 73(9), 2305-2313. doi:10.1093/jac/dky152

DOI: 10.1093/jac/dky152

Untapped Potential for Streptomycin: Using Genomics to Optimize Aminoglycoside Selection in Drug-Resistant Mycobacterium Tuberculosis (Conference Paper)

Cohen, K. A., Stott, K. E., Manson, A. L., Munsamy, V., Earl, A. M., & Pym, A. S. (2018). Untapped Potential for Streptomycin: Using Genomics to Optimize Aminoglycoside Selection in Drug-Resistant Mycobacterium Tuberculosis. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 197. Retrieved from http://gateway.webofknowledge.com/

2017

PHARMACOKINETICS OF ORALLY ADMINISTERED VORICONAZOLE IN AFRICAN PENGUINS (SPHENISCUS DEMERSUS) AFTER SINGLE AND MULTIPLE DOSES (Journal article)

Hyatt, M. W., Wiederhold, N. P., Hope, W. W., & Stott, K. E. (2017). PHARMACOKINETICS OF ORALLY ADMINISTERED VORICONAZOLE IN AFRICAN PENGUINS (SPHENISCUS DEMERSUS) AFTER SINGLE AND MULTIPLE DOSES. JOURNAL OF ZOO AND WILDLIFE MEDICINE, 48(2), 352-362. doi:10.1638/2016-0160R2.1

DOI: 10.1638/2016-0160R2.1

Therapeutic drug monitoring for invasive mould infections and disease: pharmacokinetic and pharmacodynamic considerations (Journal article)

Stott, K. E., & Hope, W. W. (2017). Therapeutic drug monitoring for invasive mould infections and disease: pharmacokinetic and pharmacodynamic considerations. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 72, I12-I18. doi:10.1093/jac/dkx029

DOI: 10.1093/jac/dkx029

2016

Clostridium difficile: A healthcare-associated infection of unknown significance in adults in sub-Saharan Africa (Journal article)

Keeley, A. J., Beeching, N. J., Stott, K. E., Roberts, P., Watson, A., & Beadsworth, M. J. (2016). Clostridium difficile: A healthcare-associated infection of unknown significance in adults in sub-Saharan Africa. MALAWI MEDICAL JOURNAL, 28(2), 66-69. doi:10.4314/mmj.v28i2.8

DOI: 10.4314/mmj.v28i2.8

Adequacy of Rifampin Absorption after Jejunostomy Tube Administration (Journal article)

Stott, K. E., Singh, B., Beadsworth, M. B. J., Vaudrey, K., Khoo, S. H., & Davies, G. (2016). Adequacy of Rifampin Absorption after Jejunostomy Tube Administration. PHARMACOTHERAPY, 36(4), E23-E25. doi:10.1002/phar.1730

DOI: 10.1002/phar.1730

Brief Report: Virologic Monitoring Can Be a Cost-Effective Strategy to Diagnose Treatment Failure on First-Line ART (Journal article)

Vandormael, A. M., Boulware, D. R., Tanser, F. C., Baernighausen, T. W., Stott, K. E., & de Oliveira, T. (2016). Brief Report: Virologic Monitoring Can Be a Cost-Effective Strategy to Diagnose Treatment Failure on First-Line ART. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 71(4), 462-466. doi:10.1097/QAI.0000000000000870

DOI: 10.1097/QAI.0000000000000870

2015

Managing potential drug-drug interactions between gastric acid-reducing agents and antiretroviral therapy: experience from a large HIV-positive cohort (Journal article)

Lewis, J. M., Stott, K. E., Monnery, D., Seden, K., Beeching, N. J., Chaponda, M., . . . Beadsworth, M. B. J. (2016). Managing potential drug-drug interactions between gastric acid-reducing agents and antiretroviral therapy: experience from a large HIV-positive cohort. INTERNATIONAL JOURNAL OF STD & AIDS, 27(2), 105-109. doi:10.1177/0956462415574632

DOI: 10.1177/0956462415574632

2014

Implementing antiretroviral resistance testing in a primary health care HIV treatment programme in rural KwaZulu-Natal, South Africa: early experiences, achievements and challenges (Journal article)

Lessells, R. J., Stott, K. E., Manasa, J., Naidu, K. K., Skingsley, A., Rossouw, T., . . . Resis, S. A. T. (2014). Implementing antiretroviral resistance testing in a primary health care HIV treatment programme in rural KwaZulu-Natal, South Africa: early experiences, achievements and challenges. BMC HEALTH SERVICES RESEARCH, 14. doi:10.1186/1472-6963-14-116

DOI: 10.1186/1472-6963-14-116

Southern African Treatment Resistance Network (SATuRN) RegaDB HIV drug resistance and clinical management database: supporting patient management, surveillance and research in southern Africa (Journal article)

Manasa, J., Lessells, R., Rossouw, T., Naidu, K., Van Vuuren, C., Goedhals, D., . . . de Oliveira, T. (2014). Southern African Treatment Resistance Network (SATuRN) RegaDB HIV drug resistance and clinical management database: supporting patient management, surveillance and research in southern Africa. DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION. doi:10.1093/database/bat082

DOI: 10.1093/database/bat082

2013

Combined antiretroviral and anti-tuberculosis drug resistance following incarceration (Journal article)

Stott, K. E., de Oliviera, T., & Lessells, R. J. (2013). Combined antiretroviral and anti-tuberculosis drug resistance following incarceration. SOUTHERN AFRICAN JOURNAL OF HIV MEDICINE, 14(3), 135-137. doi:10.7196/SAJHIVMED.957

DOI: 10.7196/SAJHIVMED.957

2009

Out of sight, out of mind? The psychosocial needs of children formerly associated with armed forces: a case study of Save the Children UK's work in Beni and Lubero territories, North Kivu province, Democratic Republic of Congo (Journal article)

Stott, K. (2009). Out of sight, out of mind? The psychosocial needs of children formerly associated with armed forces: a case study of Save the Children UK's work in Beni and Lubero territories, North Kivu province, Democratic Republic of Congo. INTERNATIONAL JOURNAL OF HEALTH PLANNING AND MANAGEMENT, 24, S52-S72. doi:10.1002/hpm.1022

DOI: 10.1002/hpm.1022