2023
Varga, A. J., Nemeth, I. B., Kemeny, L., Varga, J., Tiszlavicz, L., Kumar, D., . . . Varro, A. (2023). Elevated Serum Gastrin Is Associated with Melanoma Progression: Putative Role in Increased Migration and Invasion of Melanoma Cells.. International journal of molecular sciences, 24(23), 16851. doi:10.3390/ijms242316851DOI: 10.3390/ijms242316851
2018
Garalla, H. M., Lertkowit, N., Tiszlavicz, L., Reisz, Z., Holmberg, C., Beynon, R., . . . Varro, A. (2018). Matrix metalloproteinase (MMP)-7 in Barrett's esophagus and esophageal adenocarcinoma: expression, metabolism, and functional significance. Retrieved from https://www.webofscience.com/DOI: 10.14814/phy2.13683
2017
Varga, A., Kumar, J. D., Simpson, A. W. M., Dodd, S., Hegyi, P., Dockray, G. J., & Varro, A. (2017). Cell cycle dependent expression of the CCK2 receptor by gastrointestinal myofibroblasts: putative role in determining cell migration. PHYSIOLOGICAL REPORTS, 5(19). doi:10.14814/phy2.13394DOI: 10.14814/phy2.13394
2010
Dynamic Changes in Cytosolic and Mitochondrial ATP Levels in Pancreatic Acinar Cells (Journal article)
Voronina, S. G., Barrow, S. L., Simpson, A. W. M., Gerasimenko, O. V., Xavier, G. D. S., Rutter, G. A., . . . Tepikin, A. V. (2010). Dynamic Changes in Cytosolic and Mitochondrial ATP Levels in Pancreatic Acinar Cells. GASTROENTEROLOGY, 138(5), 1976-U111. doi:10.1053/j.gastro.2010.01.037DOI: 10.1053/j.gastro.2010.01.037
2009
Reply to Sadaba (Journal article)
Conant, A. R., & Simpson, A. W. M. (2009). Reply to Sadaba. European Journal of Cardio-Thoracic Surgery, 35(6), 1116. doi:10.1016/j.ejcts.2009.02.026DOI: 10.1016/j.ejcts.2009.02.026
Compartmentalized signalling: Ca2+ compartments, microdomains and the many facets of Ca2+ signalling. (Journal article)
Laude, A. J., & Simpson, A. W. M. (2009). Compartmentalized signalling: Ca2+ compartments, microdomains and the many facets of Ca2+ signalling.. The FEBS journal, 276(7), 1800-1816. doi:10.1111/j.1742-4658.2009.06927.xDOI: 10.1111/j.1742-4658.2009.06927.x
2008
Attenuation of receptor-dependent and -independent vasoconstriction in the human radial artery (Journal article)
Shackcloth, M. J., Conant, A. R., Thekkudan, J., Ghotkar, S., Simpson, A. W. M., & Dihmis, W. C. (2008). Attenuation of receptor-dependent and -independent vasoconstriction in the human radial artery. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 34(4), 839-844. doi:10.1016/j.ejcts.2008.06.016DOI: 10.1016/j.ejcts.2008.06.016
Potentiation of ATP- and bradykinin-induced [Ca2+]c responses by PTHrP peptides in the HaCaT cell line. (Journal article)
Burrell, H. E., Simpson, A. W. M., Mehat, S., McCreavy, D. T., Durham, B., Fraser, W. D., . . . Gallagher, J. A. (2008). Potentiation of ATP- and bradykinin-induced [Ca2+]c responses by PTHrP peptides in the HaCaT cell line.. The Journal of investigative dermatology, 128(5), 1107-1115. doi:10.1038/sj.jid.5701159DOI: 10.1038/sj.jid.5701159
Diadenosine polyphosphates are selective vasoconstrictors in human coronary artery bypass grafts. (Journal article)
Conant, A. R., Theologou, T., Dihmis, W. C., & Simpson, A. W. M. (2008). Diadenosine polyphosphates are selective vasoconstrictors in human coronary artery bypass grafts.. Vascular pharmacology, 48(4-6), 157-164. doi:10.1016/j.vph.2008.01.005DOI: 10.1016/j.vph.2008.01.005
2007
Atrial natriuretic peptide attenuates elevations in Ca2+ and protects hepatocytes by stimulating net plasma membrane Ca2+ efflux. (Journal article)
Green, A. K., Stratton, R. C., Squires, P. E., & Simpson, A. W. M. (2007). Atrial natriuretic peptide attenuates elevations in Ca2+ and protects hepatocytes by stimulating net plasma membrane Ca2+ efflux.. The Journal of biological chemistry, 282(47), 34542-34554. doi:10.1074/jbc.m707115200DOI: 10.1074/jbc.m707115200
Cell shape-dependent Control of Ca2+ influx and cell cycle progression in Swiss 3T3 fibroblasts. (Journal article)
Pennington, S. R., Foster, B. J., Hawley, S. R., Jenkins, R. E., Zolle, O., White, M. R. H., . . . Simpson, A. W. M. (2007). Cell shape-dependent Control of Ca2+ influx and cell cycle progression in Swiss 3T3 fibroblasts.. The Journal of biological chemistry, 282(44), 32112-32120. doi:10.1074/jbc.m705067200DOI: 10.1074/jbc.m705067200
Temperature changes stimulate contraction in the human radial artery and affect response to vasoconstrictors. (Journal article)
Oo, A. Y., Conant, A. R., Chester, M. R., Dihmis, W. C., & Simpson, A. W. M. (2007). Temperature changes stimulate contraction in the human radial artery and affect response to vasoconstrictors.. The Annals of thoracic surgery, 83(1), 126-132. doi:10.1016/j.athoracsur.2006.08.035DOI: 10.1016/j.athoracsur.2006.08.035
2006
Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes (Journal article)
Goldring, C. E. P., Kitteringham, N. R., Jenkins, R., Lovatt, C. A., Randle, L. E., Abdullah, A., . . . Park, B. K. (2006). Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 290(1), C104-C115. doi:10.1152/ajpcell.00133.2005DOI: 10.1152/ajpcell.00133.2005
Fluorescent measurement of [Ca2+]c: basic practical considerations. (Chapter)
Simpson, A. W. M. (2006). Fluorescent measurement of [Ca2+]c: basic practical considerations.. In Unknown Book (Vol. 312, pp. 3-36).
2005
Human keratinocytes release ATP and utilize three mechanisms for nucleotide interconversion at the cell surface. (Journal article)
Burrell, H. E., Wlodarski, B., Foster, B. J., Buckley, K. A., Sharpe, G. R., Quayle, J. M., . . . Gallagher, J. A. (2005). Human keratinocytes release ATP and utilize three mechanisms for nucleotide interconversion at the cell surface.. The Journal of biological chemistry, 280(33), 29667-29676. doi:10.1074/jbc.m505381200DOI: 10.1074/jbc.m505381200
Antioxidant enzyme activity in cultured human arterial and venous endothelial cells (Journal article)
Conant, A. R., Dihimis, W. C., & Simpson, A. W. M. (2005). Antioxidant enzyme activity in cultured human arterial and venous endothelial cells. Heart, 91(7).
2003
Regulation of [Ca2+]c oscillations by plasma membrane Ca2+ fluxes: a role for natriuretic peptides. (Journal article)
Green, A. K., Zolle, O., & Simpson, A. W. M. (2003). Regulation of [Ca2+]c oscillations by plasma membrane Ca2+ fluxes: a role for natriuretic peptides.. Biochemical Society transactions, 31(Pt 5), 934-938. doi:10.1042/bst0310934DOI: 10.1042/bst0310934
Phenoxybenzamine treatment is insufficient to prevent spasm in the radial artery: The effect of other vasodilators (Journal article)
Conant, A. R., Shackcloth, M. J., Oo, A. Y., Chester, M. R., Simpson, A. W. M., & Dihmis, W. C. (2003). Phenoxybenzamine treatment is insufficient to prevent spasm in the radial artery: The effect of other vasodilators. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 126(2), 448-454. doi:10.1016/S0022-5223(03)00388-XDOI: 10.1016/S0022-5223(03)00388-X
Regulation of [Ca2+](c) oscillations by plasma membrane Ca2+ fluxes: a role for natriuretic peptides (Journal article)
Green, A. K., Zolle, O., & Simpson, A. W. M. (2003). Regulation of [Ca2+](c) oscillations by plasma membrane Ca2+ fluxes: a role for natriuretic peptides. Biochemical Society Transactions, 31, 934-938.
2002
Atrial natriuretic peptide attenuates Ca2+ oscillations and modulates plasma membrane Ca2+ fluxes in rat hepatocytes. (Journal article)
Green, A. K., Zolle, O., & Simpson, A. W. M. (2002). Atrial natriuretic peptide attenuates Ca2+ oscillations and modulates plasma membrane Ca2+ fluxes in rat hepatocytes.. Gastroenterology, 123(4), 1291-1303. doi:10.1053/gast.2002.35994DOI: 10.1053/gast.2002.35994
Endothelin receptors in cultured and native human radial artery smooth muscle. (Journal article)
Conant, A. R., Oo, A. Y., Dashwood, M. R., Collard, K., Chester, M. R., Dihmis, W. C., & Simpson, A. W. M. (2002). Endothelin receptors in cultured and native human radial artery smooth muscle.. Journal of cardiovascular pharmacology, 39(1), 130-141. doi:10.1097/00005344-200201000-00014DOI: 10.1097/00005344-200201000-00014
Modulation of contractility in phenoxybenzamine-treated human radial arteries prepared for coronary artery bypass surgery (Journal article)
Shackcloth, M. J., Oo, A. Y., Chester, M. R., Simpson, A. W. M., Dihmis, W. C., & Conant, A. R. (2002). Modulation of contractility in phenoxybenzamine-treated human radial arteries prepared for coronary artery bypass surgery. Journal Of Physiology-London, 543, 72P.
Temperature-induced contraction in human radial artery smooth muscle (Journal article)
Oo, A. Y., Conant, A. R., Chester, M. R., Dihmis, W. C., & Simpson, A. W. M. (2002). Temperature-induced contraction in human radial artery smooth muscle. Journal Of Physiology-London, 543, 72P.
2001
A fluorescence-based method for measuring nitric oxide in extracts of skeletal muscle. (Journal article)
Sutherland, H., Khundkar, R., Zolle, O., McArdle, A., Simpson, A. W., Jarvis, J. C., & Salmons, S. (2001). A fluorescence-based method for measuring nitric oxide in extracts of skeletal muscle.. Nitric oxide : biology and chemistry, 5(5), 475-481. doi:10.1006/niox.2001.0374DOI: 10.1006/niox.2001.0374
2000
Diadenosine polyphosphates are largely ineffective as agonists at natively expressed P2Y(1) and P2Y(2) receptors on cultured human saphenous vein endothelial cells. (Journal article)
Conant, A. R., Fisher, M. J., McLennan, A. G., & Simpson, A. W. (2000). Diadenosine polyphosphates are largely ineffective as agonists at natively expressed P2Y(1) and P2Y(2) receptors on cultured human saphenous vein endothelial cells.. Journal of vascular research, 37(6), 548-555. doi:10.1159/000054088DOI: 10.1159/000054088
Activation of the particulate and not the soluble guanylate cyclase leads to the inhibition of Ca2+ extrusion through localized elevation of cGMP. (Journal article)
Zolle, O., Lawrie, A. M., & Simpson, A. W. (2000). Activation of the particulate and not the soluble guanylate cyclase leads to the inhibition of Ca2+ extrusion through localized elevation of cGMP.. The Journal of biological chemistry, 275(34), 25892-25899. doi:10.1074/jbc.m000786200DOI: 10.1074/jbc.m000786200
Elevation of mitochondrial calcium by ryanodine-sensitive calcium-induced calcium release. (Journal article)
Nassar, A., & Simpson, A. W. (2000). Elevation of mitochondrial calcium by ryanodine-sensitive calcium-induced calcium release.. The Journal of biological chemistry, 275(31), 23661-23665. doi:10.1074/jbc.m000457200DOI: 10.1074/jbc.m000457200
Cultured human saphenous vein endothelial cells are largely unresponsive to the diadenosine polyphosphates via the natively expressed P2Y receptors. (Conference Paper)
Conant, A., Fisher, M. J., McLennan, A. G., & Simpson, A. W. M. (2000). Cultured human saphenous vein endothelial cells are largely unresponsive to the diadenosine polyphosphates via the natively expressed P2Y receptors.. In Journal of Physiology-Paris Vol. 525 (pp. 84p). Elsevier.
Cultured human saphenous vein endothelial cells are largely unresponsive to the diadenosine polyphosphates via the natively expressed P2Y receptors (Journal article)
Conant, A. R., Fisher, M. J., McLennan, A. G., & Simpson, A. W. M. (2000). Cultured human saphenous vein endothelial cells are largely unresponsive to the diadenosine polyphosphates via the natively expressed P2Y receptors. Journal Of Physiology-London, 525, 84P.
Elevation of mitochondrial Ca2+ concentration by Ca2+-induced Ca2+ release in the A10 rat aortic smooth muscle cell line (Journal article)
Nassar, A., & Simpson, A. W. M. (2000). Elevation of mitochondrial Ca2+ concentration by Ca2+-induced Ca2+ release in the A10 rat aortic smooth muscle cell line. Journal Of Physiology-London, 525, 84P-85P.
Endothelin increases calcium via Et-A receptors in cultured human radial artery smooth muscle cells (Journal article)
Oo, A. Y., Conant, A. R., Chester, M. R., Dihmis, W. C., & Simpson, A. W. M. (2000). Endothelin increases calcium via Et-A receptors in cultured human radial artery smooth muscle cells. Journal Of Physiology-London, 525, 19P.
1998
Characterization of the P2 receptors on the human umbilical vein endothelial cell line ECV304. (Journal article)
Conant, A. R., Fisher, M. J., McLennan, A. G., & Simpson, A. W. (1998). Characterization of the P2 receptors on the human umbilical vein endothelial cell line ECV304.. British journal of pharmacology, 125(2), 357-364. doi:10.1038/sj.bjp.0702082DOI: 10.1038/sj.bjp.0702082
A comparison of the purinoceptor populations of primary human umbilical vein endothelial cells and the derived cell line ECV304 (Conference Paper)
Conant, A. R., Fisher, M. J., McLennan, A. G., & Simpson, A. W. M. (1998). A comparison of the purinoceptor populations of primary human umbilical vein endothelial cells and the derived cell line ECV304. In Journal of Physiology-Paris Vol. 506 (pp. 33p-34p). Elsevier.
A comparison of the purinoceptor populations of primary human umbilical vein endothelial cells and the derived cell line ECV304 (Journal article)
Conant, A. R., Fisher, M. J., McLennan, A. G., & Simpson, A. W. M. (1998). A comparison of the purinoceptor populations of primary human umbilical vein endothelial cells and the derived cell line ECV304. Journal Of Physiology-London, 506P, 33P-34P.
Activation of adenylate cyclase and PKA can mediate Ca2+ release in cultured ECV304 endothelial cells derived from the human umbilical vein (Journal article)
Hepworth, T. J., & Simpson, A. W. M. (1998). Activation of adenylate cyclase and PKA can mediate Ca2+ release in cultured ECV304 endothelial cells derived from the human umbilical vein. Journal Of Physiology-London, 506P, 19P-20P.
Cell shape regulates bombesin-activated capacitative calcium entry (Journal article)
Hawley, S. R., Zolle, O. C., Spiller, D. G., Wood, C. D., White, M. R. H., Simpson, A. W. M., & Pennington, S. R. (1998). Cell shape regulates bombesin-activated capacitative calcium entry. Molecular Biology Of The Cell, 9, 251A.
Cyclic GMP inhibits calcium extrusion from ECV304 endothelial cells derived from the human umbilical vein (Journal article)
Zolle, O. C., Lawrie, A. M., & Simpson, A. W. M. (1998). Cyclic GMP inhibits calcium extrusion from ECV304 endothelial cells derived from the human umbilical vein. Journal Of Physiology-London, 506P, 20P.
1997
Modulation of mitochondrial Ca2+ in ECV304 endothelial cells by agents which elevate cAMP. (Journal article)
Lawrie, A. M., Zolle, O., & Simpson, A. W. (1997). Modulation of mitochondrial Ca2+ in ECV304 endothelial cells by agents which elevate cAMP.. Cell calcium, 22(4), 229-234. doi:10.1016/s0143-4160(97)90061-0DOI: 10.1016/s0143-4160(97)90061-0
Okadaic acid induces the release of Ca2+ from intracellular stores in ECV304 endothelial cells. (Journal article)
Hepworth, T. J., Lawrie, A. M., & Simpson, A. W. (1997). Okadaic acid induces the release of Ca2+ from intracellular stores in ECV304 endothelial cells.. Cell calcium, 21(6), 461-467. doi:10.1016/s0143-4160(97)90057-9DOI: 10.1016/s0143-4160(97)90057-9
Calcium release from ATP-sensitive stores, evoked by okadaic acid in the human umbilical vein endothelial cell line, ECV 304 (Journal article)
Hepworth, T. J., Lawrie, A. M., & Simpson, A. W. M. (1997). Calcium release from ATP-sensitive stores, evoked by okadaic acid in the human umbilical vein endothelial cell line, ECV 304. Journal Of Physiology-London, 499P, P42-P43.
1996
A role for calcium influx in the regulation of mitochondrial calcium in endothelial cells. (Journal article)
Lawrie, A. M., Rizzuto, R., Pozzan, T., & Simpson, A. W. (1996). A role for calcium influx in the regulation of mitochondrial calcium in endothelial cells.. The Journal of biological chemistry, 271(18), 10753-10759. doi:10.1074/jbc.271.18.10753DOI: 10.1074/jbc.271.18.10753
1994
Atp-Evoked Ca2+ Influx In A Human Endothelial-Cell Line Elevates Mitochondrial Calcium As Revealed By Selectively Targeted Recombinant Aequorin (Journal article)
Lawrie, A. M., Rizzuto, R., Pozzan, T., & Simpson, A. W. M. (1994). Atp-Evoked Ca2+ Influx In A Human Endothelial-Cell Line Elevates Mitochondrial Calcium As Revealed By Selectively Targeted Recombinant Aequorin. Journal Of Physiology-London, 480P, P134-P135.
Ca2+ Store Depletion Elevates Intracellular [Na+] In Human Platelets (Journal article)
Simpson, A. W. M., Jilani, S., & Ashley, C. C. (1994). Ca2+ Store Depletion Elevates Intracellular [Na+] In Human Platelets. Journal Of Physiology-London, 477P, P10-P11.
1992
Correction: Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin (Journal article)
Rizzuto, R., Simpson, A. W. M., Brini, M., & Pozzan, T. (1992). Correction: Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin. Nature, 360(6406), 768. doi:10.1038/360768f0DOI: 10.1038/360768f0
Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin. (Journal article)
Rizzuto, R., Simpson, A. W., Brini, M., & Pozzan, T. (1992). Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin.. Nature, 358(6384), 325-327. doi:10.1038/358325a0DOI: 10.1038/358325a0
1990
Evidence for receptor-mediated bivalent-cation entry in A10 vascular smooth-muscle cells. (Journal article)
Simpson, A. W., Stampfl, A., & Ashley, C. C. (1990). Evidence for receptor-mediated bivalent-cation entry in A10 vascular smooth-muscle cells.. The Biochemical journal, 267(1), 277-280. doi:10.1042/bj2670277DOI: 10.1042/bj2670277
1989
Endothelin evoked Ca2+ transients and oscillations in A10 vascular smooth muscle cells. (Journal article)
Simpson, A. W., & Ashley, C. C. (1989). Endothelin evoked Ca2+ transients and oscillations in A10 vascular smooth muscle cells.. Biochemical and biophysical research communications, 163(3), 1223-1229. doi:10.1016/0006-291x(89)91108-xDOI: 10.1016/0006-291x(89)91108-x
Spontaneous Oscillations and Agonist-Evoked Changes in Ca2+ in Cultured Smooth Muscle Cells (Journal article)
Simpson, A. W. M., & Ashley, C. C. (1989). Spontaneous Oscillations and Agonist-Evoked Changes in Ca2+ in Cultured Smooth Muscle Cells. Journal of Cardiovascular Pharmacology, 14, S59-S62. doi:10.1097/00005344-198900146-00013DOI: 10.1097/00005344-198900146-00013
1985
Control and interrelation of aggregation and secretion; the roles of Ca2+, diacylglycerol and thromboxane with particular reference to ADP stimulation. (Chapter)
Hallam, T. J., Simpson, A. W., O'Connor, N., & Rink, T. J. (1985). Control and interrelation of aggregation and secretion; the roles of Ca2+, diacylglycerol and thromboxane with particular reference to ADP stimulation.. In Unknown Book (Vol. 192, pp. 145-162). doi:10.1007/978-1-4615-9442-0_11DOI: 10.1007/978-1-4615-9442-0_11