2024
2023
da Silva, T. B., Rendra, E., David, C. A. W., Bieback, K., Cross, M. J., Wilm, B., . . . Murray, P. (2023). Umbilical cord mesenchymal stromal cell-derived extracellular vesicles lack the potency to immunomodulate human monocyte-derived macrophages in vitro.. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 167, 115624. doi:10.1016/j.biopha.2023.115624DOI: 10.1016/j.biopha.2023.115624
Late Breaking Abstract - Age and vitamin D influence airway epithelial cells response to SARS-CoV-2 infection (Conference Paper)
Sposito, F., Pennington, S., David, C., Duggan, J., Northey, S., Biagini, G., . . . Hedrich, C. (2023). Late Breaking Abstract - Age and vitamin D influence airway epithelial cells response to SARS-CoV-2 infection. In Airway cell biology and immunopathology. European Respiratory Society. doi:10.1183/13993003.congress-2023.oa4962DOI: 10.1183/13993003.congress-2023.oa4962
Sposito, F., Pennington, S. H., A W David, C., Duggan, J., Northey, S., Biagini, G., . . . Hedrich, C. M. (2023). Age differential CD13 and interferon expression in airway epithelia affect SARS-CoV-2 infection - effects of vitamin D.. Mucosal immunology, S1933-0219(23)00064-8. doi:10.1016/j.mucimm.2023.08.002DOI: 10.1016/j.mucimm.2023.08.002
David, C., de la Fonteyne-Blankestijn, L., Vermeulen, J., Plant-Hately, A., Vandebriel, R., & Liptrott, N. (2023). Application of KU812 cells for assessing complement activation related effects by nano(bio)materials. Biomedicine and Pharmacotherapy. doi:10.1016/j.biopha.2023.114841DOI: 10.1016/j.biopha.2023.114841
Curley, P., Hobson, J. J., Liptrott, N. J., Makarov, E., Al-Khouja, A., Tatham, L., . . . Owen, A. (2023). Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations.. Pharmaceutics, 15(7), 1835. doi:10.3390/pharmaceutics15071835DOI: 10.3390/pharmaceutics15071835
2022
Plant-Hately, A. J., Eryilmaz, B., David, C. A. W., Brain, D. E., Heaton, B. J., Perrie, Y., & Liptrott, N. J. (2022). Exposure of the Basophilic Cell Line KU812 to Liposomes Reveals Activation Profiles Associated with Potential Anaphylactic Responses Linked to Physico-Chemical Characteristics. PHARMACEUTICS, 14(11). doi:10.3390/pharmaceutics14112470DOI: 10.3390/pharmaceutics14112470
Vandebriel, R. J., David, C. A. W., Vermeulen, J. P., & Liptrott, N. J. (2022). An inter-laboratory comparison of an NLRP3 inflammasome activation assay and dendritic cell maturation assay using a nanostructured lipid carrier and a polymeric nanomedicine, as exemplars. DRUG DELIVERY AND TRANSLATIONAL RESEARCH, 12(9), 2225-2242. doi:10.1007/s13346-022-01206-6DOI: 10.1007/s13346-022-01206-6
Heaton, B. J., Jensen, R. L., Line, J., David, C. A. W., Brain, D. E., Chadwick, A. E., & Liptrott, N. J. (2022). Exposure of human immune cells, to the antiretrovirals efavirenz and lopinavir, leads to lower glucose uptake and altered bioenergetic cell profiles through interactions with SLC2A1. BIOMEDICINE & PHARMACOTHERAPY, 150. doi:10.1016/j.biopha.2022.112999DOI: 10.1016/j.biopha.2022.112999
2021
Brain, D., Plant-Hately, A., Heaton, B., Arshad, U., David, C., Hedrich, C., . . . Liptrott, N. J. (2021). Drug delivery systems as immunomodulators for therapy of infectious disease: Relevance to COVID-19. ADVANCED DRUG DELIVERY REVIEWS, 178. doi:10.1016/j.addr.2021.113848DOI: 10.1016/j.addr.2021.113848
Halamoda-Kenzaoui, B., Vandebriel, R. J., Howarth, A., Siccardi, M., David, C. A. W., Liptrott, N. J., . . . Caputo, F. (2021). Methodological needs in the quality and safety characterisation of nanotechnology-based health products: Priorities for method development and standardisation. JOURNAL OF CONTROLLED RELEASE, 336, 192-206. doi:10.1016/j.jconrel.2021.06.016DOI: 10.1016/j.jconrel.2021.06.016
David, C. A. W., del Castillo Busto, M. E., Cuello-Nunez, S., Goenaga-Infante, H., Barrow, M., Fernig, D. G., . . . Liptrott, N. J. (2021). Assessment of changes in autophagic vesicles in human immune cell lines exposed to nano particles. CELL AND BIOSCIENCE, 11(1). doi:10.1186/s13578-021-00648-8DOI: 10.1186/s13578-021-00648-8
Hobson, J. J., Savage, A. C., Dwyer, A., Unsworth, C., Massam, J., Arshad, U., . . . Rannard, S. (n.d.). Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection. Nanoscale. doi:10.1039/d1nr00309gDOI: 10.1039/d1nr00309g
Rajoli, R. K. R., Pertinez, H., Arshad, U., Box, H., Tatham, L., Curley, P., . . . Owen, A. (2021). Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87(4), 2078-2088. doi:10.1111/bcp.14619DOI: 10.1111/bcp.14619
Hobson, J., Savage, A., Dwyer, A., Unsworth, C., Arshad, U., Pertinez, H., . . . Rannard, S. (2021). Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection. doi:10.26434/chemrxiv.13587035.v1DOI: 10.26434/chemrxiv.13587035.v1
Hobson, J., Savage, A., Dwyer, A., Unsworth, C., Arshad, U., Pertinez, H., . . . Rannard, S. (2021). Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection. doi:10.26434/chemrxiv.13587035DOI: 10.26434/chemrxiv.13587035
Glucose uptake in immune cells is lower in the presence of HIV antiretrovirals due to interactions with SLC transporters-An in vitro/in silico investigation (Conference Paper)
Heaton, B., Liptrott, N., & David, C. (2021). Glucose uptake in immune cells is lower in the presence of HIV antiretrovirals due to interactions with SLC transporters-An in vitro/in silico investigation. In BRITISH JOURNAL OF PHARMACOLOGY Vol. 178 (pp. 456). Retrieved from https://www.webofscience.com/
Involvement of pattern recognition receptors in the immune response to lipid-based nanoparticles in basophil cell lines (Conference Paper)
Plant-Hately, A., Liptrott, N., David, C., & Brain, D. (2021). Involvement of pattern recognition receptors in the immune response to lipid-based nanoparticles in basophil cell lines. In BRITISH JOURNAL OF PHARMACOLOGY Vol. 178 (pp. 485). Retrieved from https://www.webofscience.com/
2020
David, C. A. W., Barrow, M., Murray, P., Rosseinsky, M. J., Owen, A., & Liptrott, N. J. (n.d.). In Vitro Determination of the Immunogenic Impact of Nanomaterials on Primary Peripheral Blood Mononuclear Cells. International Journal of Molecular Sciences, 21(16), 5610. doi:10.3390/ijms21165610DOI: 10.3390/ijms21165610
Arshad, U., Pertinez, H., Box, H., Tatham, L., Rajoli, R. K., Curley, P., . . . Owen, A. (2020). Prioritisation of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics.. Clinical pharmacology and therapeutics. doi:10.1002/cpt.1909DOI: 10.1002/cpt.1909
Rajoli, R. K., Pertinez, H., Arshad, U., Box, H., Tatham, L., Curley, P., . . . Owen, A. (2020). Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.. medRxiv : the preprint server for health sciences. doi:10.1101/2020.05.01.20087130DOI: 10.1101/2020.05.01.20087130
Arshad, U., Pertinez, H., Box, H., Tatham, L., Rajoli, R. K. R., Curley, P., . . . Owen, A. (2020). Prioritisation of potential anti-SARS-CoV-2 drug repurposing opportunities based on ability to achieve adequate plasma and target site concentrations derived from their established human pharmacokinetics. doi:10.1101/2020.04.16.20068379DOI: 10.1101/2020.04.16.20068379
2018
Potential for immune modulation by inhibition of autophagic processes. (Poster)
David, C., Owen, A., & Liptrott, N. J. (2018). Potential for immune modulation by inhibition of autophagic processes.. Poster session presented at the meeting of Nanomedicine's Early Career Researchers Meeting. London.
2017
David, C., Ahmed, F., Owen, A., & Liptrott, N. (2017). Modulation of inflammasome activation through manipulation of autophagic processes in primary human immune cells.. Journal of Interdisciplinary Nanomedicine.
Assessment of the potential interactions of hyperbranched polydendrons with immunological and haematological systems. (Poster)
David, C., Giardiello, M., Rannard, S. P., Owen, A., & Liptrott, N. J. (2017). Assessment of the potential interactions of hyperbranched polydendrons with immunological and haematological systems.. Poster session presented at the meeting of BSNM Early Career Researchers' Meeting. Belfast.
2016
David, C. (2016, December 19). Assessing the relationship between nanoparticle physicochemical characteristics and biological interactions; optimisation of in vitro techniques and protocols..
David, C. A. W., Owen, A., & Liptrott, N. J. (2016). Determining the relationship between nanoparticle characteristics and immunotoxicity: key challenges and approaches. NANOMEDICINE, 11(11), 1447-1464. doi:10.2217/nnm-2016-0017DOI: 10.2217/nnm-2016-0017
David, C. (2016). Preclinical assessment of G2':2000PEG-pHPMA100EGDMA0.8 polymeric nanoparticles.. Journal of Interdisciplinary Nanomedicine.
Determining the physicochemical characteristics of nanoparticles that relate to negative effects on cellular health using in vitro systems. (Poster)
David, C., Owen, A., & Liptrott, N. J. (2016). Determining the physicochemical characteristics of nanoparticles that relate to negative effects on cellular health using in vitro systems.. Poster session presented at the meeting of University of Liverpool ITM Research Day. Liverpool.
2015
Determining the physicochemical characteristics of nanoparticles that relate to negative effects on cellular health using in vitro systems. (Poster)
David, C., Owen, A., & Liptrott, N. J. (2015). Determining the physicochemical characteristics of nanoparticles that relate to negative effects on cellular health using in vitro systems.. Poster session presented at the meeting of European Nanomedicine Meeting. Grenoble.
Optimisation of higher throughput assays for assessing the impact of nanomaterials on autophagy. (Poster)
David, C., Liptrott, N. J., & Owen, A. (2015). Optimisation of higher throughput assays for assessing the impact of nanomaterials on autophagy.. Poster session presented at the meeting of University of Liverpool Poster Day. Liverpool.
Optimisation of methodology to assess the impact of nanomaterials on autophagy. (Poster)
David, C., Owen, A., & Liptrott, N. J. (2015). Optimisation of methodology to assess the impact of nanomaterials on autophagy.. Poster session presented at the meeting of BSNM Young Researcher Meeting. Liverpool.
Utility of kinetic measurement of oxidative stress in nanotoxicological assay development. (Poster)
David, C., Raymant, M. L., Owen, A., & Liptrott, N. J. (2015). Utility of kinetic measurement of oxidative stress in nanotoxicological assay development.. Poster session presented at the meeting of Nanotechnology in Medicine. Manchester.
