Pharmacology BSc (Hons) Add to your prospectus

  • Offers study abroad opportunities Offers study abroad opportunities
  • Opportunity to study for a year in China Offers a Year in China

Key information


  • Course length: 3 years
  • UCAS code: B210
  • Year of entry: 2019
  • Typical offer: A-level : AAB / IB : 34 / BTEC : DDD in relevant diploma
life-sciences-4

Module details

Year One Compulsory Modules

  • Molecules and Cells (LIFE101)
    Level1
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting80:20
    Aims

    After successful completion of this module, students will be able to:

    1. Recognise the basic of structure, composition and function of cells;
    2. Explain core concepts relating to the organisation and specialisation of eukaryotes, prokaryotes and viruses;
    3. Define the cellular components involved in the regulation of key functions such as the generation of energy, movement, cell growth and division and differentiation;
    4. Describe the latest techniques that are used in cell biology to determine cell structure and function;
    5. Develop in students the knowledge and understanding of the subject and the ability to apply, evaluate and interpret this knowledge to solve problems.
    Learning Outcomes

    On successful completion of the module students will be able to:

    1. Describe how cells arose and their structural features;
    2. Compare and contrast eukaryotic and prokaryotic cells;
    3. Identify the different ways cells manipulate energy;
    4. Define the molecular basis of the processes by which cells grow, replicate, communicate, interact with their environment, move and die;
    5. Describe the functional importance of cell specialisation and cooperation in tissues.
  • Evolution (LIFE103)
    Level1
    Credit level15
    SemesterFirst Semester
    Exam:Coursework weighting80:20
    Aims

    This module aims to:

    1. Describe fundamental genetic mechanisms that are essential for the function and evolution of life;
    2. Introduce students to fundamental evolutionary concepts and theories, showing how genetic mechanisms help determine the patterns of observed evolution;
    3. Apply evolutionary concepts to a broad selection of areas of Life Sciences;
    4. Develop in students the knowledge and understanding of the subject and the ability to apply, evaluate and interpret this knowledge to solve problems in biology.
    Learning Outcomes

    Recall how cells evolved

    ​Identify the causes of evolutionary change in populations

    ​Recognize the consequences of evolutionary change for patterns of biological diversity within and amongst populations

    ​Recall fundamental genetic mechanisms (heredity, mutation, meiosis, sex) and show how they influence evolutionary change in populations

    Recognize the widespread applicability of evolutionary ideas across the Life Sciences

  • Grand Challenges in Biology (LIFE105)
    Level1
    Credit level7.5
    SemesterFirst Semester
    Exam:Coursework weighting60:40
    Aims
    1. To encourage students to become aware of the themes that are driving biological research in Liverpool and globally;
    2. To engage students with their programme of study;
    3. To excite student interest in their subject and the way it relates to the challenges that face us all;
    4. To foster the development of study skills that will equip students to investigate research topics and communicate their findings and views on them.
    Learning Outcomes

    To identify the grand challenges that face biological scientists

    ​To put into context the advances that science makes possible and the ethical issues associated with meeting the Grand Challenges

    ​To evaluate different approaches to the resolution of scientific questions

    ​To conduct an independent piece of research and report their findings to their peers

  • Experimental Skills in Current Biology (LIFE107)
    Level1
    Credit level15
    SemesterWhole Session
    Exam:Coursework weighting30:70
    Aims

    1.      Introducestudents to a range of practical skills and techniques that are of general usein subjects across the Life Sciences;

    2.      Demonstratethe relevance of experimental skills across all biological disciplines andexplain the importance of observing good laboratory practice

    3.      Trainstudents how to observe and record experiments, and how to present and analysedata

     ​

      Learning Outcomes​​​​​​​​​​​​​​​​​​​​​​ Record procedures and protocols for experiments relating to current biology and generate, evaluate andinterpret qualitative and quantitative data

      Identify, formulate andtest hypotheses in relation to laboratory- based experiments in current biology​

      Use laboratory equipment correctly and safely according to good laboratory practice and observing Health and Safety rules

      Demonstrate a range of laboratory skills when undertaking experiments in current biology

    1. Essential Skills for the Life Sciences I (LIFE109)
      Level1
      Credit level15
      SemesterWhole Session
      Exam:Coursework weighting0:100
      Aims

      This module aims to:

      1. Develop in students the essential skills that they will require to be competent life scientists;
      2. Enhance the employability prospects of students.
      Learning Outcomes

      Use a range of mathematical and numerical tools to address biological problems

      Structure and communicate ideas effectively, both orally and in writing

      ​Manage time, work to deadlines and prioritise workloads 

      ​Actively participate in groups but be capable of independent work

      ​Find relevant information and use IT effectively

      ​Address the relevance and ideas of others 

      ​Evaluate own performance and working standards 

    2. Introduction to Physiology and Pharmacology (LIFE106)
      Level1
      Credit level15
      SemesterSecond Semester
      Exam:Coursework weighting80:20
      Aims

      This module aims to:

      1. Provide students with a grounding in the concepts and principles that underlie human systems biology;
      2. Introduce the concepts of interactions of drugs and other exogenous chemicals on biological processes;
      3. Develop concepts of drug absorption and the relationship between chemical structure and drug action;
      4. Develop knowledge and understanding in physiology and pharmacology, and ability to apply, evaluate and interpret this knowledge to solve problems in these disciplines.
      Learning Outcomes

      On successful completion of this module, the students will be able to:

      1.  Describe homeostasis and its maintenance;
      2.  Define osmosis and hydrostatic pressure;
      3.  Outline the fundamentals of membrane potentials and how they are influenced;
      4.  Explain the roles played in various body systems in organism maintenance;
      5.  Distinguish how body systems interact in response to external stressors;
      6.  Define the way in which pharmacology is studied and drugs are developed;
      7.  Describe the properties of receptors;
      8.  Identify the chemical interactions between drugs and receptors;
      9.  Define and use the terms absorption, distribution and metabolism of drugs.
    3. Biological Chemistry (LIFE104)
      Level1
      Credit level15
      SemesterSecond Semester
      Exam:Coursework weighting80:20
      Aims
    4. This module aims to develop in students: Knowledge and understanding of the chemical reactions that underpin biological processes
    5. ​Awareness of the chemical processes that are required to understand pharmacological principles

    6. ​The ability to apply, evaluate and interpret this knowledge to solve problems, in biochemistry, pharmacology and biomedicine.

    7. Learning OutcomesApply basic thermodynamic principles to biological systems and energetics

      ​Identify the principles of electronic structure and organic and bioinorganic chemical reactions, and their analysis

      ​Describe the anomalous properties of water and their importance in biological systems

      ​Use the principles of chemical reaction rates to quantify enzymatic reactions and pharmacokinetics

      Explain the application of basic spectroscopic techniques

      ​Describe how these chemical and thermodynamic principles explain key biological mechanisms

    8. Biochemical Methods (LIFE122)
      Level1
      Credit level7.5
      SemesterSecond Semester
      Exam:Coursework weighting50:50
      Aims

        This module aims to:

      1. Introduce students to a range of practical skills and analytical techniques that are applicable to many fields of modern biology;
      2. Explain to students the importance of working safely in the laboratory in accord with Health and Safety protocols and good working practices;
      3. Train students how to observe and record experiments, and how to present and analyse data;
      4. Demonstrate the relevance of experimental skills across all biological disciplines and the essential relationship between quantitative skills and key skills;
      5. Develop knowledge and understanding in biochemistry, biotechnology and biomedicine, and ability to apply, evaluate and interpret this knowledge to solve problems.
      Learning Outcomes

      Record, evaluate and interpret qualitative and quantitative data, and record procedures and protocols;

      Plan and execute a series of experiments;​

      ​Use laboratory equipment correctly and safely to generate data;​

      ​Identify, formulate and test hypotheses in relation to laboratory based experimental design;​

      ​Demonstrate good laboratory practice in relation to Health and Safety in the laboratory and good working practices.​

    Year One Optional Modules

    • Biochemistry and Biomedical Sciences (LIFE102)
      Level1
      Credit level15
      SemesterSecond Semester
      Exam:Coursework weighting80:20
      Aims

      After successful completion of this module, students will be able to:

      1. Describe the major dietary components for humans and other organisms, and the processes that result in their digestion and absorption;
      2. Explain the mechanisms and processes that regulate carbohydrate, fat and protein metabolism;
      3. Define how imbalances in nutrition can lead to lifestyle diseases and how genetic or infectious diseases can result in impaired ability to generate energy;
      4. Develop knowledge and understanding in biochemistry and biomedicine, and ability to apply, evaluate and interpret this knowledge to solve problems.
      Learning Outcomes

      On successful completion of this module, the students should be able to:

      1. Describe the important groups of diseases affecting humans and other organisms;
      2. Explain the processes involved in the control and regulation of metabolism and how their dysfunction results in lifestyle diseases;
      3. Identify the genetic mechanisms that underlie inherited diseases affecting oxygen transport and storage;
      4. Define the processes involved in bacterial and viral infectious disease and the mechanisms that protect organisms from infection.
    • Applied Genetic and Molecular Technologies (LIFE108)
      Level1
      Credit level15
      SemesterSecond Semester
      Exam:Coursework weighting80:20
      AimsThis module aims to:
      1. Provide students with the knowledge and understanding of the structure of nucleic acids and how these molecules encode the properties of cells;
      2. Develop knowledge and understanding of the mechanisms that lead to inheritance in offspring;
      3. Equip students tobe able to describe the basic techniques that are used to experimentally clone genes and analyse their structure and function;
      4. Develop students'' knowledge and understanding in genetics and molecular biology, and their ability to apply, evaluate and interpret this knowledge to solve problems, in these disciplines. 
      5. P.MsoNormal{text-align:justify;margin:0cm 0cm 0pt;font-family:Arial;font-size:10pt;}LI.MsoNormal{text-align:justify;margin:0cm 0cm 0pt;font-family:Arial;font-size:10pt;}DIV.MsoNormal{text-align:justify;margin:0cm 0cm 0pt;font-family:Arial;font-size:10pt;}.MsoChpDefault{font-family:Calibri;font-size:11pt;}.MsoPapDefault{line-height:115%;margin-bottom:10pt;}DIV.WordSection1{page:WordSection1;}Introduce students to the ethical implications of genetic and molecular technologies.
      Learning Outcomes

      Explain the molecular processes that occur to produce variation in the offspring;

      and how to interpret Mendelian and non-Mendelian patterns of inheritance;

      ​Explain how to apply molecular technologies to isolate and characterise nucleic acids and design and interpret basic experiments to clone and analyse genes;

      ​Show how molecular biology technologies might be used to solve problems in biology, food security, veterinary science and medicine;

      ​Develop an appreciation of the ethical issues associated with genetic and molecular technologies.

    • Microbiology (LIFE110)
      Level1
      Credit level15
      SemesterSecond Semester
      Exam:Coursework weighting80:20
      Aims

      This module aims to:

      1. Describe how microbes play crucial roles in maintaining the natural environment;
      2. Explain the role of microbes in disease processes and how the immune system protects against infections;
      3. Highlight the roles of microbes in biotechnological processes;
      4. Develop knowledge and understanding in microbiology, and ability to apply, evaluate and interpret this knowledge to solve problems in Microbiology.
      Learning Outcomes

      On successful completion of this module, the students will be able to:

      1. Identify appropriate techniques for assessing microbial diversity with particular reference to bacteria and fungi;
      2. Describe the structure and significance of microbial communities involving these species;
      3. Explain the physiological properties and adaptations that enable microbes to colonise diverse environments;
      4. Define the roles of microbes as commensals and pathogens and mechanisms by which they interact with the host;
      5. Describe the roles that microbes play in nutrient and biomass recycling;
      6. Define the environmental and biotechnological importance of microbes in specific contexts, including food security and water treatment.
    • Animal Biodiversity (LIFE112)
      Level1
      Credit level15
      SemesterSecond Semester
      Exam:Coursework weighting80:20
      Aims
    • To foster in students an understanding of structure and function of the basic body plan of the major groups of animals

    • ​To encourage the appreciation of the evolutionary origins of the basic body plan of animals;

    • ​To develop an understanding of how the basic body plan of animals has been modified to adapt to different modes of existence and habitats

    • ​To develop knowledge and understanding in animal biodiversity, and the ability to apply, evaluate and interpret this knowledge to solve problems in zoology.

    • Learning Outcomes

      To identify the structure and function of the basic body plan of the major invertebrate and chordate groups, and the diversity within the groups that has arisen through evolution

      To ​recognize how the basic body plan of animals has been modified to adapt to different modes of existence and habitats

      To ​read and interpret phylogenetic trees
    • Developmental Biology: Embryology and Mechanisms of Development (LIFE114)
      Level1
      Credit level15
      SemesterSecond Semester
      Exam:Coursework weighting80:20
      Aims

      This module aims to:

      1. Describe the processes that regulate development and the general properties of stem cells;
      2. Explain the mechanisms of germ line development and early development from fertilisation to gastrulation; 
      3. Provide students with an understanding of how the major organ systems of the body form;
      4. Highlight the experimental evidence underpinning this knowledge;
      5. Develop knowledge and understanding in human biology, and ability to apply, evaluate and interpret this knowledge to solve problems.
      Learning Outcomes

      Explain the fundamental mechanisms that regulate development;

      ​Describe the general properties of stem cells and their role in development;

      ​Explain the developmental processes that form the three layered embryo and the experimental evidence that underpins our understanding; 

    • Describe the formation of the main organs of the body from the ectoderm, mesoderm and endoderm;
    • ​Explain the basic mechanisms that regulate the development of the major organ systems and the experimental models used to investigate these mechanisms.

    Year Two Compulsory Modules

    • Principles of Pharmacology (LIFE207)
      Level2
      Credit level15
      SemesterFirst Semester
      Exam:Coursework weighting80:20
      Aims
    • This module aims to: Develop an understanding of the quantitative aspects of drug action on cellular receptors;

    • Demonstrate the relationship between drug efficacy and chemical structure;

    • Introduce the basic principles of pharmacokinetics, outline the relationship between drug concentration and response, and include an introduction to the principles of toxicity of drugs and their metabolites;

    • Provide knowledge of the molecular biology of receptors;

    • Develop knowledge and understanding in pharmacology, and the ability to apply, evaluate and interpret this knowledge to solve pharmacological problems.

    • Learning OutcomesOn successful completion of this module, the students should be able to: Describe quantitative aspects of drug action;​Define the relationship between drug efficacy and chemical structure;​State key pharmacokinetic concepts such as clearance, volume of distribution, half life and steady state and to solve problems involving these parameters;​Demonstrate the role of drug concentrations in determining response to treatment;​Describe early biochemical events after drug administration that are of toxicological and biochemical significance;​Describe the principles of selective toxicity and their application to both self and non-self targets;​Demonstrate knowledge and critical understanding of the principles of pharmacology, and how this knowledge has been applied to solve problems.​
    • Drug Action (LIFE206)
      Level2
      Credit level15
      SemesterSecond Semester
      Exam:Coursework weighting100:0
      Aims
      1. Enable students to develop their understanding of the cardiovascular, endocrine and central nervous systems and the mechanisms by which drugs interact with physiological processes operating within each of these systems;​​
      2. Provide an insight into the mechanisms of immune function and dysfunction, and the actions of drugs that target the immune system;
      3. Give students a grounding in the fundamental principles of signal transduction from metabotropic receptors, and their significance for drug action;​
      4. Provide and overview of the overall drug development process, with a focus on the safety and efficacy tests applied during clinical trials, and the value-for-money tests applied during NICE approval;
      5. Develop knowledge and understanding in pharmacology, and ability to apply, evaluate and interpret this knowledge to solve problems.
        Learning Outcomes

        ​Identify the effects of drugs on the CNS and demonstrate an understanding of how drugs may be used to treat neurological and neuropsychiatric disorders;

        ​Describe the action of drugs in the cardiovascular system and their role in the treatment of cardiovascular disease;

        Compare the effects of drugs on the kidney, the endocrine system and the gastrointestinal tract;Describe the principles underlying the effects of drugs on the immune system and the treatment of autoimmune disease;​Apply knowledge how the signal transduction pathways can be modulated to enhance cancer therapy;​

        Apply the knowledge of the regulatory framework underlying the testing and approval of drugs;

      1. Pharmacological Chemistry (CHEM038)
        Level2
        Credit level15
        SemesterSecond Semester
        Exam:Coursework weighting90:10
        Aims

        ​The aim of this module is to offer students a grounding in organic chemistry and spectroscopy that is directly relevant to Pharmacology. There will be a particular emphasis on relating each topic studied to pharmacological examples.

        Learning Outcomes​​Upon successful completion of this module, a student will be able to demonstrate an understanding of the structure and bonding in a range of molecules, from simple organics to larger biologically relevant structures.Upon successful completion of this module, a student will be able to demonstrate an understanding of​​the significant role of stereochemistry and conformation in a pharmacological setting

        ​Upon successful completion of this module, a student will be able to demonstrate an understanding ofan array of chemical reactions

        ​Upon successful completion of this module, a student will be able to demonstrate an understanding of a range of spectroscopic methods

        Upon successful completion of this module, a student will be able to demonstrate an understanding of​the chemical principles in both the synthesis of biologically relevant structures and their interactions with small molecules

        ​Upon successful completion of this module, a student will be able to apply these concepts and principles to process and solve unseen organic chemistry problems.

      2. Essential Skills for the Life Sciences 2 (LIFE223)
        Level2
        Credit level15
        SemesterWhole Session
        Exam:Coursework weighting30:70
        Aims
        1. To further develop the essential life science skills that students will require to succeed in their studies and future careers;

        2. To enhance the career awareness and employability prospects of students;

        3. To enable students to analyse and interpret scientific data and communicate results to a range of audiences.

        Learning Outcomes

        ​Structure and communicate ideas effectively, both orally and in writing;

        Find information through literature searches and use IT effectively to analyse and report findings;​Competently utilise a range of mathematical and numerical skills relevant to all biologists;​Summarise and interpret advanced data using graphs and tables;​Develop and test hypotheses;​Within the context of experimental design and within a range of biological fields, select appropriate quantitative methods to answer questions;​Apply appropriate statistical and other analysis packages to analyse data;​Interpret and evaluate quantitative terms and approaches used in the scientific literature;​

        ​Effectively communicate a biological subject to a lay audience

        Recognise the moral and ethical issues of scientific investigations and discuss ethical standards and professional codes of conduct. ​​
      3. Practical Pharmacology (LIFE234)
        Level2
        Credit level7.5
        SemesterSecond Semester
        Exam:Coursework weighting50:50
        Aims​This module aims are:
        1. To give students practical experience in many of the techniques specifically used in the study of Pharmacology​​.
        2. To provide students with a better understanding of relevant pharmacological principles.
        3. To develop in students the ability to evaluate and analyse experimental data.
        Learning Outcomes​To present and interpret qualitative and quantitative pharmacological data and record procedures and protocols accurately.

        ​To explain pharmacological mechanisms underpinning pharmacokinetics, pharmacodynamics and drug toxicity.

        To plan and execute a series of experiments to explore drug distribution, drug metabolism, drug toxicity, drug receptor interactions and the effects of drugs on behaviour.

        ​To analyse data, interpret validity and apply statistical analyses.

      4. Chemical Techniques (CHEM022)
        Level2
        Credit level7.5
        SemesterSecond Semester
        Exam:Coursework weighting0:100
        Aims

        The aim of this module is to introduce students to the basic techniques used in synthetic organic chemistry.

        Learning Outcomes

        Upon successful completion of the module, a student is expected to possess proficiency with basic techniques of synthetic chemistry (setting up reactions, product isolation,purification techniques and analytic characterization).

        ​Upon successful completion of the module, a student is expected to have the basic understanding of electronic search methods for chemical information using specialized databases

        ​Upon successful completion of the module, a student is expected to have basic ability to interpret 1H NMR, MS and IR spectra of simple organic molecules

        ​Upon successful completion of the module, a student is expected to have basic understanding of scientifc writing

      Year Two Optional Modules

      • Endocrine and Neuro-physiology (LIFE204)
        Level2
        Credit level15
        SemesterSecond Semester
        Exam:Coursework weighting70:30
        Aims
      • ​Explain the essential background knowledge to understand basic neuroscience;

      • ​Describe the basic principles of operation of nervous system, systematic and sensory neurophysiology, excitotoxicity and behaviour;

      • Provide an understanding of physiological homeostatic regulatory mechanisms, with particular regard to the endocrine and digestive systems;

      • Develop knowledge and understanding in physiology, and ability to apply, evaluate and interpret this knowledge to solve physiological problems.
      • Learning Outcomes

        ​Describe the basic principles of the nervous system, systematic and sensory neurophysiology, excitotoxicity and behaviour; and the characteristics of nerve cells that allow them facilitate the reception, processing and transmission of information;

        ​Apply the above knowledge to the operation of some of these systems, through all the stages from transduction of a stimulus to conscious perception, the regulatory mechanisms employed by them, their importance in maintaining homeostasis and the consequences of malfunction;

        Demonstrate specific knowledge and critical understanding of physiological functions of the digestive tract and major endocrine glands and apply this to understand the interaction between the digestive, endocrine and nervous system;​

        Demonstrate knowledge and critical understanding of the principles of physiology, and how this knowledge has been applied to solve physiological problems.

      • Molecular and Medical Genetics (LIFE208)
        Level2
        Credit level15
        SemesterSecond Semester
        Exam:Coursework weighting100:0
        Aims
        1. Introduce students with an interest in genetics and molecular biology to the range of biological mechanisms that control the structure and stability of the genetic material;

        2. Provide an understanding of how changes in the structure and stability of DNA can impact on health and disease;

        3. Use examples from both prokaryotes and eukaryotes to develop principles that help explain problems associated with medical/clinical genetics;

        4. Develop knowledge and understanding in genetics and molecular biology, and ability to apply, evaluate and interpret this knowledge to solve problems.

          Learning Outcomes​Describe and discuss the principles of DNA replication, DNA damage and mutation, DNA repair, DNA recombination, genetic transfer systems and transposition, cell cycle control and cell division, genetic mapping and cytogenetics;

          ​Explain how these processes underpin an appreciation of the genetic basis of human health and disease;

          ​Solve problems by applying the above knowledge to identify genes underlying disease and the likely causes of DNA mutations;

        1. The Multicellular Organism: Tissues, Development, Regeneration and Aging (LIFE205)
          Level2
          Credit level15
          SemesterFirst Semester
          Exam:Coursework weighting80:20
          AimsExtend students'' knowledge of the structure and function of fundamental tissues, such as epithelial and connective tissue and of specialised tissues; 
          Develop students'' ability to discuss the mechanisms by which cells differentiate to form different tissues;
          Equip students to explain the processes that occur during ageing with special reference to changes in key tissues such as the brain;
          Develop knowledge and understanding in human biology, and ability to apply, evaluate and interpret this knowledge to solve problems in that subject.​
          Learning OutcomesClassify and compare the major types of epithelia and, explain the role of cell-cell interactions in tissue structure and the structure and function of fundamental tissues

          Discuss and compare the molecular mechanisms involved in development of selected organs, and their cellular structure and organisation and explain the molecular and cellular mechanisms involved in the regeneration of key organs.Explain and discuss mechanisms of ageing using selected systems as exemplars.

          Describe the experimental basis underpinning the current understanding of tissue biology. ​

        2. The Immune System in Health and Disease (LIFE221)
          Level2
          Credit level15
          SemesterFirst Semester
          Exam:Coursework weighting80:20
          AimsThis module aims to:
          1. ​Develop students’ knowledge of the immune system and its role in protection against disease
          2. Develop in students an appreciation of the importance of different immune mechanisms in different circumstances, and how these can be evaded.
          3. Enable students to evaluate and appreciate the consequences of immune system dysfunctions in disease.​
          Learning Outcomes

          ​Identify the main components of the mammalian immune system

          ​Assess the contribution of innate and adaptive immune mechanisms to host defences

          Assess the mechanisms that permit recognition of an infinitely diverse microflora Discuss the impact of malfunction of immune processes on human health, and explain the bases of autoimmunity and allergy together with the mechanisms by which these can be minimised 

          ​Discuss how dysfunction of immune system constituents can cause disease

        3. Cell Signalling in Health and Disease (LIFE202)
          Level2
          Credit level15
          SemesterSecond Semester
          Exam:Coursework weighting80:20
          Aims
          ​This module aims to: 1. Provide students with knowledge and understanding of the molecular mechanisms that allow cells to communicate with each other
          ​2. Explain the general principles of these signalling mechanisms and then describe some of these in more detail;
          3. Illustrate how defects in these signalling processes can result in a variety of diseases;
          4. Outline the techniques that are used to investigate and define these pathways and to describe how these techniques are used in drug discovery programmes of research;
          5. Develop in students the ability to apply, evaluate and interpret this knowledge and understanding, to solve problems in molecular cell biology
            Learning Outcomes

            ​On successful completion of this module, the students should be able to:

             Describe the fundamental features of a range of common cell signalling mechanisms;

            ​Explain how cell signalling processes may be defective, or modified, in a variety of different diseases;

            ​Demonstrate knowledge of the molecular and biochemical nature and role of the different components of intracellular signalling pathways;

            ​Demonstrate knowledge and critical understanding of the principles of cell signalling, and how this knowledge has been applied to solve problems in biological science.

          1. E-biology: Informatics for Life Sciences (LIFE225)
            Level2
            Credit level7.5
            SemesterFirst Semester
            Exam:Coursework weighting100:0
            Aims
            • Provide students with a practical appreciation of the nature and significance of digital data.
            • Expose students to bioinformatics tools used in the analysis of data from areas such as genome sequencing, gene expression and protein structure studies
            • ​Enable students to utilize digital data for understanding higher order phenomena within cells such as metabolism, gene regulation and protein-protein interaction
            • Develop students’ knowledge and understanding of the subject and the ability to apply, evaluate and interpret this knowledge to solve problems in biotechnology, biomedicine and molecular cell biology. ​​

              Learning Outcomes

              ​·         Apply informatics tools in the discovery, evaluation and acquisition of biological data.

              ​​

              ·         Analyse and evaluate datasets of broad biological relevance, using tasks and workflows that will prepare them for third-year projects.​


              ·         Use local and web-based tools for data analysis, management and collaborative working.​ ​ ​

              ​·         ​Design research methods in bioinformatics to solve biological problems.​​
            1. E-biology: Informatics for Life Sciences (s2) (LIFE242)
              Level2
              Credit level7.5
              SemesterSecond Semester
              Exam:Coursework weighting100:0
              Aims
              1. Provide students with a practical appreciation of the nature and significance of digital data.
              2. Expose students to bioinformatics tools used in the analysis of data from areas such as genome sequencing, gene expression and protein structure studies
              3. ​Enable students to utilize digital data for understanding higher order phenomena within cells such as metabolism, gene regulation and protein-protein interaction
              4. Develop students’ knowledge and understanding of the subject and the ability to apply, evaluate and interpret this knowledge to solve problems in biotechnology, biomedicine and molecular cell biology.​
              Learning Outcomes

              ​·         Apply informatics tools in the discovery, evaluation and acquisition of biological data.

              ​​​

              ​·         Analyse and evaluate datasets of broad biological relevance, using tasks and workflows that will prepare them for third-year projects.​


              ·         Use local and web-based tools for data analysis, management and collaborative working.​ ​ ​

              ​​

              ​ ·          ​Design research methods in bioinformatics to solve biological problems.​​​
            2. Advanced Biochemical Techniques (LIFE224)
              Level2
              Credit level7.5
              SemesterSecond Semester
              Exam:Coursework weighting0:100
              Aims
            3. ​This module aims to:

               Provide students with a practical training in a number of techniques used in biochemistry, including analysis of enzyme activity and stability and protein purification and analysis using chromatography and electrophoresis;​
            4. Develop in students the knowledge, understanding and ability to design experiments, and to apply, evaluate and interpret experimental data to solve problems in biochemistry and molecular cell biology.

            5. Learning Outcomes

              ​Present, critically evaluate and interpret qualitative and quantitative data, and record procedures and protocols;

              ​Develop team-working and individual skills, learn to manage time effectively and use laboratory equipment correctly and safely to generate data;

              Plan and execute a series of biochemical experiments to analyse protein structure and function;​

              Analyse data, interpret its validity and apply statistical analyses.

            6. Molecular Science (LIFE237)
              Level2
              Credit level7.5
              SemesterFirst Semester
              Exam:Coursework weighting60:40
              Aims
              1. ​Provide students with practical experience in a number of techniques used in molecular biology;

              2. ​Equip student to perform analysis of DNA fragments by agarose gel electrophoresis;

              3. ​Introduce students to PCR based-assays for gene cloning and demonstrate methods used for cloning, and analysing genes

              4. ​Develop in students knowledge and understanding in biomedicine, biotechnology and molecular cell biology, and the ability to apply, evaluate and interpret this knowledge to solve biomolecular problems.

                 
              Learning Outcomes

              ​Present , evaluate critcally and interpret qualitative and quantitative molecular biology data;

              ​Plan and execute a series of molecular biology experiments to demonstrate practical skills in molecular biology;

              ​Analyse and interpret the validity of experimental data;

              ​Summarise scientific investigations

            7. Practical Human Physiology (LIFE229)
              Level2
              Credit level7.5
              SemesterFirst Semester
              Exam:Coursework weighting20:80
              Aims
            8. ​To provide students with a practical training in the study of physiology and how to measure physiological variables;

            9. ​To equip students with the ability to apply appropriate statistical tools to define the normal range of physiological variables;

            10. To develop in students knowledge and understanding in physiology, and the ability to apply, evaluate and interpret this knowledge to solve physiological problems.

            11. Learning OutcomesOn completion of this module student will be able to: Elucidate the principles of practical physiology;

              ​Measure and interpret the cardiovascular and respiratory variables most commonly dealt with in human physiology;

              Correctly measure volumes to the internationally recognised standard temperature and pressure values.

              Demonstrate the most effective ways of presenting data, including the presentation of a poster.

              Apply statistical concepts of mean, median, mode, standard deviation and standard error, and know the circumstances in which it is appropriate to use a Student''s t-test.

              Design studies, using the techniques acquired, to investigate a physiological principle.​

            Year Three Compulsory Modules

            • Chemotherapy and Cellular Pharmacology (LIFE312)
              Level3
              Credit level15
              SemesterSecond Semester
              Exam:Coursework weighting80:20
              Aims

              ​1. To develop the principles and concepts introduced in Level 5 modules on antibacterial chemotherapy and apply them to diseases caused by viruses (e.g. HIV/AIDS), bacteria (e.g. TB) and parasites (e.g. Malaria).

              2.  To develop in students specialist knowledge and understanding in pharmacology.

              3.  To develop in students the ability to apply, critically evaluate and interpret this knowledge to solve complex problems in pharmacology.

              Learning Outcomes

              ​To critically evaluate the principles of selective toxicity as applied to the chemotherapy of infectious disease.

              ​To assess the clinical relevance of basic pharmacological principles of chemotherapy.

              ​To evaluate the importance of drug resistance in the treatment and prevention of disease.

              ​To evaluate modern pharmacological approaches to chemotherapy.

            • Cardiovascular and Respiratory Pharmacology (LIFE313)
              Level3
              Credit level15
              SemesterFirst Semester
              Exam:Coursework weighting80:20
              Aims
              1. ​To provide students with the opportunity to develop advanced knowledge and understanding of cardiovascular and respiratory pharmacology​

              2. ​To develop in students an awareness of how dysfunction in these systems can be treated with current drugs, and how improved understanding can lead to improved drugs

              3. ​​​To raise awareness of the specific problems associated with drug side-effects in the cardiovascular system, and the approaches taken to test for these in drug development

              Learning Outcomes

              ​To critically discuss the pathophysiology of major cardiovascular andrespiratory diseases

              ​To appraise current knowledge of the mechanisms of action and side-effects of current drugsat the molecular, cellular, organ and systemic levels in health and disease

              ​​​​To discussthe latest understanding of principles underlying the development of new drugsfor the treatment of cardiovascular and respiratory diseases

            • Drug Metabolism and Drug Response (LIFE315)
              Level3
              Credit level15
              SemesterFirst Semester
              Exam:Coursework weighting80:20
              Aims

                

              1. To demonstrate the relevance and importance of the principles of drug metabolism and pharmacokinetics
              2. ​To explain the importance of the relationship between drug disposition and drug response
              3. ​​​​To develop in students the ability to apply, critically evaluate and interpret this knowledge and understanding, to solve complex problems in pharmacology

                 

                 

              Learning Outcomes

              ​To appraise the principles of drug disposition and drug response, particularly in relation to why subjects differ in their response to drugs

              ​To critically discuss the relevance of basic pharmacokinetic principles to achieving a good response to therapy

              ​​To critically analyse pharmacokinetic data

               

              ​​​To evaluate the dispositional basis of adverse drug reactions

              To critically discuss the relevant physicochemical characteristics of nanomaterials that relate to their interactions with biological systems.

            • Cancer Pharmacology (LIFE314)
              Level3
              Credit level15
              SemesterSecond Semester
              Exam:Coursework weighting80:20
              Aims

              ​To provide an explanation of current understanding of cancer development and progression and how this is exploited in the rational design of drugs to target cancer.

              To explain to students the latest knowledge of the molecular mechanisms of anti-cancer drugs and the potential for side-effects, drug toxicity and drug-resistance.
               To develop in students a critical understanding of the clinical effectiveness and cost-effectiveness of modern cancer drugs.
              Learning Outcomes

              ​To evaluate the pathophysiological process of cancerdevelopment and progression​

              To critically evaluate the rationale for the design and mechanism ofaction of anti-cancer agents​

              ​To assess  the potential fortoxicity and side-effects and drug resistance in anti-cancer drugs​

              ​To evaluate current ideas on the mechanisms of drug-resistance incancer therapy

               

              ​To critically evaluate scientific literature and clinical dataregarding the efficacy and cost-effectiveness of anti-cancer therapy inpatients


            • Molecular and Neuropharmacology (LIFE317)
              Level3
              Credit level15
              SemesterFirst Semester
              Exam:Coursework weighting80:20
              Aims

              ​To provide a contemporary review of drug treatment for the most common disorders of the brain, focusing on pathophysiology, receptors and ion channels as drug targets, and the mechanisms of action of key classes of neuropharmacological agents 

              Learning Outcomes

              ​Evaluate the central role of excitatory and inhibitory neurotransmission in the nervous system in health and disease​

              ​Identify major classes of drug targets in the nervous system and explain how those targets interact with intracellular effector mechanisms​

              ​Analyse the characteristic features of epilepsy, the range of drugs available for its treatment, and how those drugs interact with specific targets in the brain​

              ​Evaluate current hypotheses to explain cell loss in neurodegenerative diseases and explain how drugs can arrest the symptoms of those disorders and how neuroimaging is helping to improve understanding of the underlying pathology

               ​

            • Molecular Toxicology (LIFE316)
              Level3
              Credit level15
              SemesterSecond Semester
              Exam:Coursework weighting80:20
              Aims

              ​1. To familiarize students with current concepts of mechanisms by which cells are killed by toxic chemicals with particular emphasis on drugs

               2. To develop in students an understanding of the main defence mechanisms that cells possess to protect them against chemical toxicity 3. To develop in students knowledge and deep understanding in pharmacology , and ability to apply, critically evaluate and interpret this knowledge to solve complex problems
              Learning Outcomes

              ​To evaluate the principal ways in which cells are killed by drugs

              ​To appraise current knowledge of the major defence mechanisms that cells possess

              ​To critically evaluate current understanding of irreversible toxicity

              ​To assess current approaches to the pre-clinical investigation of various types of toxicity 

            • Pharmacology Research Projects (PHAR660)
              Level3
              Credit level30
              SemesterWhole Session
              Exam:Coursework weighting0:100
              Aims

              The aims of this module are:

              • To provide an opportunity to extensively research a specific topic (or topics)
              • To afford insights into contemporary scientific methods and debate
              • To encourage the development of independent working and critical appraisal skills
              Learning Outcomes

              ​To undertake academic research in an efficient, safe and responsible manner

              ​To search, index and evaluate the scientific literature for the purposes of pharmacological study

              ​To plan, perform and record progress of studies that explore specific scientific questions and hypotheses

              ​To analyse and evaluate scientific data and information and draw informed conclusions

              ​To prepare written reports that effectively communicate scientific findings to the reader

              ​To prepare and deliver oral and poster presentations that effectively communicate scientific findings to the respective audience(s)

            Programme Year Four

            Students can transfer into the C900 (MBiolSci) programme to complete a four-year integrated master’s. This offers industrial placements in UK or abroad (subject to performance).

            The programme detail and modules listed are illustrative only and subject to change.


            Teaching and Learning

            You will experience a range of learning environments during your studies at Liverpool. These will include student-centred activities as well as lectures, tutorials, laboratory practicals, dissection classes, fieldwork, data handling sessions and computer workshops. Some of these activities will be performed individually, such as personal research projects, and others in small tutorial or project groups, in addition to formal lectures and workshops. You will have research staff as well as your own academic adviser for individual tuition on our acclaimed tutorial programme.


            Assessment

            As well as factual knowledge and understanding, biologists need practical and organisational skills, and an ability to work both alone and with other people. We record development of these abilities through continuous assessment during the semester and by final examination. You will also prepare posters, complete tests, analyse data, give short talks, research the scientific literature and write essays and reports. The style of examination progresses from short answers towards the essay format in the later years of each degree programme, as your understanding deepens.