2023
Pye, C., Green, D., Anderson, J., Fitzgerald, M., Phelan, M., Comerford, E., & Peffers, M. (2023). Determining predictive metabolomic biomarkers of meniscal injury in dogs with cranial cruciate ligament rupture.. Journal of Small Animal Practice.
Turlo, A. J., Hammond, D. E., Ramsbottom, K. A., Soul, J., Gillen, A., McDonald, K., & Peffers, M. J. (2023). Mesenchymal Stromal Cell Secretome Is Affected by Tissue Source and Donor Age.. Stem cells (Dayton, Ohio), 41(11), 1047-1059. doi:10.1093/stmcls/sxad060DOI: 10.1093/stmcls/sxad060
Anderson, J. R., Johnson, E., Jenkins, R., Jacobsen, S., Green, D., Walters, M., . . . Peffers, M. J. (2023). Multi-Omic Temporal Landscape of Plasma and Synovial Fluid-Derived Extracellular Vesicles Using an Experimental Model of Equine Osteoarthritis.. International journal of molecular sciences, 24(19), 14888. doi:10.3390/ijms241914888DOI: 10.3390/ijms241914888
Pye, C., Clark, N., Bruniges, N., Peffers, M., & Comerford, E. (n.d.). Current evidence for non-pharmaceutical, non-surgical treatments of canine osteoarthritis. Journal of Small Animal Practice. doi:10.1111/jsap.13670DOI: 10.1111/jsap.13670
Chabronova, A., van den Akker, G., Housmans, B. A. C., Caron, M. M. J., Cremers, A., Surtel, D. A. M., . . . Welting, T. J. M. (2023). Depletion of <i>SNORA33</i> Abolishes ψ of 28S-U4966 and Affects the Ribosome Translational Apparatus. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(16). doi:10.3390/ijms241612578DOI: 10.3390/ijms241612578
Collins, J. A., Kim, C. J., Coleman, A., Little, A., Perez, M. M., Clarke, E. J., . . . Loeser, R. F. (2023). Cartilage-specific <i>Sirt6</i> deficiency represses IGF-1 and enhances osteoarthritis severity in mice.. Annals of the rheumatic diseases, ard-2023-224385. doi:10.1136/ard-2023-224385DOI: 10.1136/ard-2023-224385
Stassen, R. H. M. J., van den Akker, G. G. H., Surtel, D. A. M., Housmans, B. A. C., Cremers, A., Caron, M. M. J., . . . Welting, T. J. M. (2023). Unravelling the Basic Calcium Phosphate crystal-dependent chondrocyte protein secretome; a role for TGF-β signaling.. Osteoarthritis and cartilage, 31(8), 1035-1046. doi:10.1016/j.joca.2023.02.079DOI: 10.1016/j.joca.2023.02.079
Hulme, C. H., Peffers, M. J., Roberts, S., Gallacher, P., Jermin, P., & Wright, K. T. (2023). Proteomic Analyses of Autologous Chondrocyte Implantation Plasma Highlight Cartilage Acidic Protein 1 as a Candidate for Preclinical Screening. AMERICAN JOURNAL OF SPORTS MEDICINE, 51(6), 1422-1433. doi:10.1177/03635465231156616DOI: 10.1177/03635465231156616
Balaskas, P., Goljanek-Whysall, K., Clegg, P. D., Fang, Y., Cremers, A., Smagul, A., . . . Peffers, M. J. (2023). MicroRNA Signatures in Cartilage Ageing and Osteoarthritis. BIOMEDICINES, 11(4). doi:10.3390/biomedicines11041189DOI: 10.3390/biomedicines11041189
Winstanley-Zarach, P., Rot, G., Kuba, S., Smagul, A., Peffers, M. J. J., & Tew, S. R. R. (2023). Analysis of RNA Polyadenylation in Healthy and Osteoarthritic Human Articular Cartilage. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(7). doi:10.3390/ijms24076611DOI: 10.3390/ijms24076611
REGENERATIVE POTENTIAL OF EXTRACELLULAR VESICLES FROM MULTIPLE SOURCES (Journal article)
Anderson, J., Riasat, K., James, V., & Peffers, M. J. (2023). REGENERATIVE POTENTIAL OF EXTRACELLULAR VESICLES FROM MULTIPLE SOURCES. OSTEOARTHRITIS AND CARTILAGE, 31, S234. Retrieved from https://www.webofscience.com/
Chabronova, A., van den Akker, G. G. H., Housmans, B. A. C., Caron, M. M. J., Cremers, A., Surtel, D. A. M., . . . Welting, T. J. M. (2023). Ribosomal RNA-based epitranscriptomic regulation of chondrocyte translation and proteome in osteoarthritis. OSTEOARTHRITIS AND CARTILAGE, 31(3), 374-385. doi:10.1016/j.joca.2022.12.010DOI: 10.1016/j.joca.2022.12.010
Anderson, J., Jenkins, R., Welting, T., Green, D., Johnson, E., Jocobsen, S., & Peffers, M. J. (2023). TEMPORAL PROTEOMIC LANDSCAPE OF PLASMA AND SYNOVIAL FLUID DERIVED EXTRACELLULAR VESICLES USING AN EXPERIMENTAL MODEL OF EQUINE OSTEOARTHRITIS. OSTEOARTHRITIS AND CARTILAGE, 31, S345. Retrieved from https://www.webofscience.com/
Goljanek-Whysall, K., Tew, S., Peffers, M. J., & Kanakis, I. (2023). Editorial: Epigenetic regulation of the musculoskeletal system in health, disease, and aging. FRONTIERS IN ENDOCRINOLOGY, 14. doi:10.3389/fendo.2023.1143210DOI: 10.3389/fendo.2023.1143210
Housmans, B. A. C., van den Akker, G. G. H., Neefjes, M., Timur, U. T., Cremers, A., Peffers, M. J., . . . Welting, T. J. M. (2023). Direct comparison of non-osteoarthritic and osteoarthritic synovial fluid-induced intracellular chondrocyte signaling and phenotype changes. OSTEOARTHRITIS AND CARTILAGE, 31(1), 60-71. doi:10.1016/j.joca.2022.09.004DOI: 10.1016/j.joca.2022.09.004
Castanheira, C. I., Anderson, J. R., Clarke, E. J., Taylor, S. E., Hackl, M., Clegg, P., . . . Peffers, M. J. (2023). EXTRACELLULAR VESICLE MICRORNA CROSSTALK BETWEEN EQUINE CHONDROCYTES AND SYNOVIOCYTES - AN <i>IN VITRO</i> APPROACH. In OSTEOARTHRITIS AND CARTILAGE Vol. 31 (pp. S338). Retrieved from https://www.webofscience.com/
Bernard, A., Vandeweerd, J. -M., Simon, V., Houbotte, D., Peffers, M. J., Welting, T., & Hontoir, F. (2023). FAT PAD ALTERATIONS WITH AGEING AND OSTEOARTHRITIS IN AN OVINE MODEL. In OSTEOARTHRITIS AND CARTILAGE Vol. 31 (pp. S317-S318). Retrieved from https://www.webofscience.com/
The effect of maternal and early-life nutrition on redox homeostasis (Chapter)
Ersoy, U., Alameddine, M., Kanakis, I., Staunton, C. A., Peffers, M. J., Jackson, M. J., . . . Vasilaki, A. (2023). The effect of maternal and early-life nutrition on redox homeostasis. In Modulation of Oxidative Stress (pp. 71-80). Elsevier. doi:10.1016/b978-0-443-19247-0.00002-3DOI: 10.1016/b978-0-443-19247-0.00002-3
2022
Baker, M. E. E., Lee, S., Clinton, M., Hackl, M., Castanheira, C., Peffers, M. J. J., & Taylor, S. E. E. (2022). Investigation of MicroRNA Biomarkers in Equine Distal Interphalangeal Joint Osteoarthritis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(24). doi:10.3390/ijms232415526DOI: 10.3390/ijms232415526
Clarke, E. J., Johnson, E., Caamaño Gutierrez, E., Andersen, C., Berg, L. C., Jenkins, R. E., . . . Peffers, M. J. (2022). Temporal extracellular vesicle protein changes following intraarticular treatment with integrin α10β1-selected mesenchymal stem cells in equine osteoarthritis.. Frontiers in veterinary science, 9, 1057667. doi:10.3389/fvets.2022.1057667DOI: 10.3389/fvets.2022.1057667
Pye, C., Bruniges, N., Peffers, M., & Comerford, E. (2022). Advances in the pharmaceutical treatment options for canine osteoarthritis. JOURNAL OF SMALL ANIMAL PRACTICE, 63(10), 721-738. doi:10.1111/jsap.13495DOI: 10.1111/jsap.13495
Peffers, M. (2022). The role of extracellular vesicle miRNAs and tRNAs in synovial fibroblast senescence. Frontiers in Molecular Biosciences. doi:10.3389/fmolb.2022.971621DOI: 10.3389/fmolb.2022.971621
Wijesinghe, S. N., Anderson, J., Brown, T. J., Nanus, D. E., Housmans, B., Green, J. A., . . . Peffers, M. J. (2022). The role of extracellular vesicle miRNAs and tRNAs in synovial fibroblast senescence. In FRONTIERS IN MOLECULAR BIOSCIENCES Vol. 9. doi:10.3389/fmolb.2022.971621DOI: 10.3389/fmolb.2022.971621
Clarke, E. J., Lima, C., Anderson, J. R., Castanheira, C., Beckett, A., James, V., . . . Peffers, M. J. (2022). Optical photothermal infrared spectroscopy can differentiate equine osteoarthritic plasma extracellular vesicles from healthy controls. ANALYTICAL METHODS. doi:10.1039/d2ay00779gDOI: 10.1039/d2ay00779g
Anderson, J. R., Jacobsen, S., Walters, M., Bundgaard, L., Diendorfer, A., Hackl, M., . . . Peffers, M. J. (n.d.). Small non-coding RNA landscape of extracellular vesicles from a post-traumatic model of equine osteoarthritis. Frontiers in Veterinary Science, 9. doi:10.3389/fvets.2022.901269DOI: 10.3389/fvets.2022.901269
Steinbusch, M. M. F., van den Akker, G. G. H., Cremers, A., Witlox, A. M. A., Staal, H. M., Peffers, M. J., . . . Welting, T. J. M. (2022). Adaptation of the protein translational apparatus during ATDC5 chondrogenic differentiation. NON-CODING RNA RESEARCH, 7(2), 55-65. doi:10.1016/j.ncrna.2022.02.003DOI: 10.1016/j.ncrna.2022.02.003
Data Integration for Big Data analytics to identify the gaps in Rheumatoid Arthritis Genomics in a Post-GWAS era (Conference Paper)
Jahangir, S., John, P., Bhatti, A., Aslam, M. M., & Peffers, M. J. (2022). Data Integration for Big Data analytics to identify the gaps in Rheumatoid Arthritis Genomics in a Post-GWAS era. In 2022 2nd International Conference on Advance Computing and Innovative Technologies in Engineering (ICACITE). IEEE. doi:10.1109/icacite53722.2022.9823601DOI: 10.1109/icacite53722.2022.9823601
Shorter, E., Avelar, R., Zachariou, M., Spyrou, G. M., Raina, P., Smagul, A., . . . Poulet, B. (n.d.). Identifying Novel Osteoarthritis-Associated Genes in Human Cartilage Using a Systematic Meta-Analysis and a Multi-Source Integrated Network. International Journal of Molecular Sciences, 23(8), 4395. doi:10.3390/ijms23084395DOI: 10.3390/ijms23084395
Clarke, E. J., Lima, C., Anderson, J. R., Castanheira, C., Hyett, J., Goodacre, R., & Peffers, M. J. (2022). NOVEL SPECTROSCOPY TECHNIQUES USED TO INTERROGATE EQUINE OSTEOARTHRITIC EXTRACELLULAR VESICLES. OSTEOARTHRITIS AND CARTILAGE, 30, S95-S96. Retrieved from https://www.webofscience.com/
Regardh, S., Jacobsen, S., Bundgaard, L., Walters, M., Anderson, J., Castanheira, C., & Peffers, M. J. (2022). SYNOVIAL FLUID SNORNAS METANALYSIS IN EQUINE OSTEOARTHRITIS. OSTEOARTHRITIS AND CARTILAGE, 30, S351. Retrieved from https://www.webofscience.com/
Jahangir, S., John, P., Bhatti, A., Aslam, M. M., Mehmood Malik, J., Anderson, J. R., & Peffers, M. J. (n.d.). LC-MS/MS-Based Serum Protein Profiling for Identification of Candidate Biomarkers in Pakistani Rheumatoid Arthritis Patients. Life, 12(3), 464. doi:10.3390/life12030464DOI: 10.3390/life12030464
Peffers, M. J., & Webster, L. C. (2022). Open Research-What is it, and how can <i>Equine Veterinary Journal's</i> authors engage with Open Research initiatives?. EQUINE VETERINARY JOURNAL, 54(2), 197-200. doi:10.1111/evj.13546DOI: 10.1111/evj.13546
Guitart-Mampel, M., Urquiza, P., Carnevale Neto, F., Anderson, J. R., Hambardikar, V., Scoma, E. R., . . . Solesio, M. E. (n.d.). Mitochondrial Inorganic Polyphosphate (polyP) Is a Potent Regulator of Mammalian Bioenergetics in SH-SY5Y Cells: A Proteomics and Metabolomics Study. Frontiers in Cell and Developmental Biology, 10. doi:10.3389/fcell.2022.833127DOI: 10.3389/fcell.2022.833127
Chabronova, A., van den Akker, G. G., Housmans, B. A., Caron, M. M., Cremers, A., Surtel, D. A., . . . Welting, T. J. (2022). DYNAMIC RIBOSOMES IN OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 30 (pp. S349-S350). Retrieved from https://www.webofscience.com/
van den Akker, G. G. H., Caron, M. M. J., Peffers, M. J., & Welting, T. J. M. (2022). Ribosome dysfunction in osteoarthritis. CURRENT OPINION IN RHEUMATOLOGY, 34(1), 61-67. doi:10.1097/BOR.0000000000000858DOI: 10.1097/BOR.0000000000000858
Caron, M. M. J., Eveque, M., Cillero-Pastor, B., Heeren, R. M. A., Housmans, B., Derks, K., . . . Welting, T. J. M. (2022). SOX9 DETERMINES TRANSLATIONAL CAPACITY DURING EARLY CHONDROGENIC DIFFERENTIATION OF ATDC5 CELLS BY REGULATING EXPRESSION OF RIBOSOME BIOGENESIS FACTORS AND RIBOSOMAL PROTEINS. In TISSUE ENGINEERING PART A Vol. 28 (pp. S385-S386). Retrieved from https://www.webofscience.com/
TRANSCRIPTOMIC EXPRESSION COMPARISON BETWEEN THE MEDIAL AND LATERAL FEMORAL CARTILAGE OF SHEEP (Conference Paper)
Hontoir, F., Peffers, M. J., Welting, T., Steijns, J., Simon, V., & Vandeweerd, J. -M. (2022). TRANSCRIPTOMIC EXPRESSION COMPARISON BETWEEN THE MEDIAL AND LATERAL FEMORAL CARTILAGE OF SHEEP. In OSTEOARTHRITIS AND CARTILAGE Vol. 30 (pp. S344-S345). Retrieved from https://www.webofscience.com/
USE OF A 3′ RNA SEQUENCING APPROACH TO DETERMINE DIFFERENTIAL TRANSCRIPT EXPRESSION AND ALTERNATIVE POLYADENYLATION SITE USAGE BETWEEN AGE MATCHED, HEALTHY AND OSTEOARTHRITIC KNEE CARTILAGE (Conference Paper)
Winstanley-Zarach, P., Kuba, S., Smagul, A., Peffers, M. J., Rot, G., & Tew, S. R. (2022). USE OF A 3′ RNA SEQUENCING APPROACH TO DETERMINE DIFFERENTIAL TRANSCRIPT EXPRESSION AND ALTERNATIVE POLYADENYLATION SITE USAGE BETWEEN AGE MATCHED, HEALTHY AND OSTEOARTHRITIC KNEE CARTILAGE. In OSTEOARTHRITIS AND CARTILAGE Vol. 30 (pp. S351-S352). Retrieved from https://www.webofscience.com/
2021
Chabronova, A., van den Akker, G. G. H., Meekels-Steinbusch, M. M. F., Friedrich, F., Cremers, A., Surtel, D. A. M., . . . Welting, T. J. M. (2021). Uncovering pathways regulating chondrogenic differentiation of CHH fibroblasts. NON-CODING RNA RESEARCH, 6(4), 211-224. doi:10.1016/j.ncrna.2021.12.003DOI: 10.1016/j.ncrna.2021.12.003
Ali, S. A., Pastrello, C., Kaur, N., Peffers, M. J., Ormseth, M. J., & Jurisica, I. (2021). A Network Biology Approach to Understanding the Tissue-Specific Roles of Non-Coding RNAs in Arthritis. FRONTIERS IN ENDOCRINOLOGY, 12. doi:10.3389/fendo.2021.744747DOI: 10.3389/fendo.2021.744747
Clarke, E. J., Gillen, A., Turlo, A., & Peffers, M. J. (2021). An Evaluation of Current Preventative Measures Used in Equine Practice to Maintain Distal Forelimb Functionality: A Mini Review. FRONTIERS IN VETERINARY SCIENCE, 8. doi:10.3389/fvets.2021.758970DOI: 10.3389/fvets.2021.758970
Ali, S. A., Peffers, M. J., Ormseth, M. J., Jurisica, I., & Kapoor, M. (2021). The non-coding RNA interactome in joint health and disease. Nature Reviews Rheumatology. doi:10.1038/s41584-021-00687-yDOI: 10.1038/s41584-021-00687-y
Marr, N., Meeson, R., Kelly, E. F., Fang, Y., Peffers, M. J., Pitsillides, A. A., . . . Thorpe, C. T. (2021). CD146 Delineates an Interfascicular Cell Sub-Population in Tendon That Is Recruited during Injury through Its Ligand Laminin-α4. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(18). doi:10.3390/ijms22189729DOI: 10.3390/ijms22189729
Caron, M. M. J., Eveque, M., Cillero-Pastor, B., Heeren, R. M. A., Housmans, B., Derks, K., . . . Welting, T. J. M. (2021). Sox9 Determines Translational Capacity During Early Chondrogenic Differentiation of ATDC5 Cells by Regulating Expression of Ribosome Biogenesis Factors and Ribosomal Proteins. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 9. doi:10.3389/fcell.2021.686096DOI: 10.3389/fcell.2021.686096
Castanheira, C. I. G. D., Anderson, J. R., Fang, Y., Milner, P. I., Goljanek-Whysall, K., House, L., . . . Peffers, M. J. (2021). Mouse microRNA signatures in joint ageing and post-traumatic osteoarthritis. Osteoarthritis and Cartilage Open, 100186. doi:10.1016/j.ocarto.2021.100186DOI: 10.1016/j.ocarto.2021.100186
Kanakis, I., Alameddine, M., Folkes, L., Moxon, S., Myrtziou, I., Ozanne, S. E., . . . Vasilaki, A. (2021). Small-RNA Sequencing Reveals Altered Skeletal Muscle microRNAs and snoRNAs Signatures in Weanling Male Offspring from Mouse Dams Fed a Low Protein Diet during Lactation. CELLS, 10(5). doi:10.3390/cells10051166DOI: 10.3390/cells10051166
Hulme, C. H., Peffers, M. J., Harrington, G. M. B., Wilson, E., Perry, J., Roberts, S., . . . Wright, K. T. (2021). Identification of Candidate Synovial Fluid Biomarkers for the Prediction of Patient Outcome After Microfracture or Osteotomy. AMERICAN JOURNAL OF SPORTS MEDICINE, 49(6), 1512-1523. doi:10.1177/0363546521995565DOI: 10.1177/0363546521995565
Clarke, E. J., Anderson, J. R., & Peffers, M. J. (2021). Nuclear magnetic resonance spectroscopy of biofluids for osteoarthritis. BRITISH MEDICAL BULLETIN, 137(1), 28-41. doi:10.1093/bmb/ldaa037DOI: 10.1093/bmb/ldaa037
Kanakis, I., Alameddine, M., Folkes, L., Moxon, S., Myrtziou, I., Ozanne, S., . . . Vasilaki, A. (2021). Small-RNA sequencing reveals altered skeletal muscle microRNAs and snoRNAs signatures in weanling male offspring from mouse dams fed a low protein diet during lactation. doi:10.1101/2021.02.22.432208DOI: 10.1101/2021.02.22.432208
Castanheira, C., Balaskas, P., Falls, C., Ashraf-Kharaz, Y., Clegg, P., Burke, K., . . . Peffers, M. J. (2021). Equine synovial fluid small non-coding RNA signatures in early osteoarthritis. BMC VETERINARY RESEARCH, 17(1). doi:10.1186/s12917-020-02707-7DOI: 10.1186/s12917-020-02707-7
Riasat, K., Cockell, S. J., Green, D. C., Pease, L. I., & Peffers, M. J. (2021). EPIGENETIC CHANGES IN AGEING HUMAN TENDON TISSUE. In OSTEOARTHRITIS AND CARTILAGE Vol. 29 (pp. S309-S310). Retrieved from https://www.webofscience.com/
Timur, U. T., Jahr, H., Anderson, J., Green, D. C., Emans, P. J., Smagul, A., . . . Welting, T. J. M. (2021). Identification of tissue-dependent proteins in knee OA synovial fluid. OSTEOARTHRITIS AND CARTILAGE, 29(1), 124-133. doi:10.1016/j.joca.2020.09.005DOI: 10.1016/j.joca.2020.09.005
Castanheira, C., James, V., Taylor, S., Skioldebrand, E., Clegg, P. D., & Peffers, M. J. (2021). SYNOVIAL FLUID AND SERUM SMALL NON-CODING RNA SIGNATURES IN EQUINE OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 29 (pp. S162). Retrieved from https://www.webofscience.com/
Small Nucleolar RNA Expression Profiling in Cartilage (Chapter)
Peffers, M. J., Cremers, A., & Welting, T. J. M. (2021). Small Nucleolar RNA Expression Profiling in Cartilage. In CHONDROCYTES (Vol. 2245, pp. 135-149). doi:10.1007/978-1-0716-1119-7_10DOI: 10.1007/978-1-0716-1119-7_10
2020
Peffers, M. J., Chabronova, A., Balaskas, P., Fang, Y., Dyer, P., Cremers, A., . . . Welting, T. J. M. (2020). SnoRNA signatures in cartilage ageing and osteoarthritis. In SCIENTIFIC REPORTS Vol. 10. doi:10.1038/s41598-020-67446-zDOI: 10.1038/s41598-020-67446-z
Epigenetic mechanisms in tendon ageing (Journal article)
Riasat, K., Bardell, D., Goljanek-Whysall, K., Clegg, P., & Peffers, M. (n.d.). Epigenetic mechanisms in tendon ageing. British Medical Bulletin. doi:10.1093/bmb/ldaa023DOI: 10.1093/bmb/ldaa023
Mennan, C., Hopkins, T., Channon, A., Elliott, M., Johnstone, B., Kadir, T., . . . Roberts, S. (2020). The use of technology in the subcategorisation of osteoarthritis: a Delphi study approach. Osteoarthritis and Cartilage Open, 100081. doi:10.1016/j.ocarto.2020.100081DOI: 10.1016/j.ocarto.2020.100081
Peffers, M. (2020). Impaired chondrocyte U3 snoRNA expression in osteoarthritis impacts the chondrocyte protein translation apparatus. Scientific Reports, 10. doi:10.1038/s41598-020-70453-9DOI: 10.1038/s41598-020-70453-9
Balaskas, P., Green, J. A., Haqqi, T. M., Dyer, P., Kharaz, Y. A., Fang, Y., . . . Peffers, M. J. (2020). Small Non-Coding RNAome of Ageing Chondrocytes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(16). doi:10.3390/ijms21165675DOI: 10.3390/ijms21165675
Anderson, J. R., Phelan, M. M., Foddy, L., Clegg, P. D., & Peffers, M. J. (2020). Ex-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study.. Journal of proteome research. doi:10.1021/acs.jproteome.0c00143DOI: 10.1021/acs.jproteome.0c00143
Anderson, J. R., Phelan, M. M., Rubio-Martinez, L. M., Fitzgerald, M. M., Jones, S. W., Clegg, P. D., & Peffers, M. J. (2020). Optimization of Synovial Fluid Collection and Processing for NMR Metabolomics and LC-MS/MS Proteomics. Journal of Proteome Research, 19(7), 2585-2597. doi:10.1021/acs.jproteome.0c00035DOI: 10.1021/acs.jproteome.0c00035
Peffers, M. J., Chabronova, A., Balaskas, P., Fang, Y., Dyer, P., Cremers, A., . . . Welting, T. J. M. (2020). SnoRNA signatures in cartilage ageing and osteoarthritis.. Scientific Reports, 10. doi:10.1038/s41598-020-67446-zDOI: 10.1038/s41598-020-67446-z
Kharaz, Y., Fang, Y., Welting, T., Peffers, M., & Comerford, E. (2020). Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis. doi:10.1101/2020.05.14.20101048DOI: 10.1101/2020.05.14.20101048
Anderson, J., Phelan, M., Caamaño-Gutiérrez, E., Clegg, P., Rubio-Martinez, L., & Peffers, M. (2020). Metabolomic and Proteomic Stratification of Equine Osteoarthritis. doi:10.1101/2020.05.04.077305DOI: 10.1101/2020.05.04.077305
Castanheira, C., Balaskas, P., Falls, C., Ashraf-Kharaz, Y., Clegg, P., Burke, K., . . . Peffers, M. J. (2020). Equine synovial fluid small non-coding RNA signatures in early osteoarthritis. doi:10.1101/2020.05.01.066027DOI: 10.1101/2020.05.01.066027
Ripmeester, E. G., Caron, M. M., Balaskas, P., Dyer, P., Chabronova, A., van den Akker, G. G., . . . Welting, T. J. (2020). IMPAIRED CHONDRCOYTE U3 SNORNA EXPRESSION IN OSTEOARTHRITIS AND ITS IMPACT ON THE CHONDROCYTE'S PROTEIN TRANSLATION APPARATUS. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S47). Retrieved from https://www.webofscience.com/
Peffers, M. J., Balaskas, P., Fang, Y., Green, J. A., Haqqi, T. M., & Welting, T. J. (2020). SMALL NON-CODING RNA SIGNATURES IN CARTILAGE AGEING. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S347-S348). Retrieved from https://www.webofscience.com/
Pimlott, Z., Hontoir, F., Kharaz, Y. A., Anderson, J., Dyer, P., Collins, J., . . . Peffers, M. J. (2020). SMALL NUCLEOLAR RNAS AS MEDIATORS OF OXIDATIVE STRESS IN CROSS SPECIES CARTILAGE AND OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S342). Retrieved from https://www.webofscience.com/
van den Akker, G. G., Surtel, D. A., Chabronova, A., Housmans, B. A., Caron, M. M., Peffers, M. J., & Welting, T. J. (2020). TGF-BETA INDUCES RIBOSOME ACTIVITY, ALTERS RIBOSOME COMPOSITION AND INHIBITS IRES-MEDIATED TRANSLATION IN CHONDROCYTES. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S348-S349). Retrieved from https://www.webofscience.com/
Peffers, M. J., Dale, A. G., Clough, H., Dyer, P., Ellis, J., Tew, S., . . . Welting, T. (2020). THE ROLE OF SNORD116 IN CARTILAGE AGEING AND OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S342-S343). Retrieved from https://www.webofscience.com/
Anderson, J., Phelan, M., Foddy, L., Clegg, P., & Peffers, M. (2020). <i>Ex-Vivo</i>Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study. doi:10.1101/2020.03.03.974501DOI: 10.1101/2020.03.03.974501
2019
Mcdermott, B., Peffers, M., McDonagh, B., & Tew, S. R. (2019). Translational regulation contributes to the secretory response of chondrocytic cells following exposure to Interleukin-1β. Journal of Biological Chemistry, 294(35), 13027-13029. doi:10.1074/jbc.RA118.006865DOI: 10.1074/jbc.RA118.006865
Balaskas, P., Whysall, K., Clegg, P., Welting, T., & Peffers, M. (2019). Defining the role and mechanism of microRNAs in osteoarthritis. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A10). Retrieved from https://www.webofscience.com/
Anderson, J. R., Smagul, A., Simpson, D., Clegg, P. D., Rubio-Martinez, L. M., & Peffers, M. J. (2019). The synovial fluid proteome differentiates between septic and nonseptic articular pathologies. JOURNAL OF PROTEOMICS, 202. doi:10.1016/j.jprot.2019.04.020DOI: 10.1016/j.jprot.2019.04.020
Peffers, M. J., Smagul, A., & Anderson, J. R. (2019). Proteomic analysis of synovial fluid: current and potential uses to improve clinical outcomes. EXPERT REVIEW OF PROTEOMICS, 16(4), 287-302. doi:10.1080/14789450.2019.1578214DOI: 10.1080/14789450.2019.1578214
COMPARISON MICRORNAS EXPRESSION IN NORMAL AND RUPTURED CANINE CRUCIATE LIGAMENTS (Conference Paper)
Kharaz, Y. A., Peffers, M., & Comerford, E. (2019). COMPARISON MICRORNAS EXPRESSION IN NORMAL AND RUPTURED CANINE CRUCIATE LIGAMENTS. In OSTEOARTHRITIS AND CARTILAGE Vol. 27 (pp. S477). doi:10.1016/j.joca.2019.02.524DOI: 10.1016/j.joca.2019.02.524
THE GATE TO CONTROLLING CHONDROGENIC DIFFERENTIATION: TRANSCRIPTIONAL REGULATION BY SOX9 IN ATDC5 CELLS (Conference Paper)
Caron, M. M., Derks, K., Sanderink, L., van Rhijn, L., Peffers, M., & Welting, T. (2019). THE GATE TO CONTROLLING CHONDROGENIC DIFFERENTIATION: TRANSCRIPTIONAL REGULATION BY SOX9 IN ATDC5 CELLS. In OSTEOARTHRITIS AND CARTILAGE Vol. 27 (pp. S196). doi:10.1016/j.joca.2019.02.303DOI: 10.1016/j.joca.2019.02.303
Steinbusch, M. M. F., Caron, M. M. J., Surtel, D. A. M., van den Akker, G. G. H., van Dijk, P. J., Friedrich, F., . . . Welting, T. J. M. (2019). The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion.. The Journal of Biological Chemistry, 294(13), 5121-5136. doi:10.1074/jbc.ra119.007356DOI: 10.1074/jbc.ra119.007356
Paraskevaidi, M., Hook, P. D., Morais, C. L. M., Anderson, J. R., White, R., Martin-Hirsch, P. L., . . . Martin, F. L. (2019). Attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy to diagnose osteoarthritis in equine serum.. Equine veterinary journal. doi:10.1111/evj.13115DOI: 10.1111/evj.13115
Bardell, D. A., Milner, P., Whysall, K., & Peffers, M. (2019). Differences in plasma and peritoneal fluid proteomes identifies potential biomarkers associated with survival following strangulating small intestinal disease. Equine Veterinary Journal. doi:10.1111/evj.13094DOI: 10.1111/evj.13094
Peffers, M. J. (2019). The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion. Journal of Biological Chemistry. doi:10.1074/jbc.RA119.007356DOI: 10.1074/jbc.RA119.007356
Comparison of RNA extraction methods in equine synovial fluid in the determination of the expression of small non-coding RNAs (Conference Paper)
Kharaz, Y. A., Comerford, E., & Peffers, M. (2019). Comparison of RNA extraction methods in equine synovial fluid in the determination of the expression of small non-coding RNAs. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A23). Retrieved from https://www.webofscience.com/
Peffers, M. J., Smaghul, A., Balaska, P., Fang, Y., & Welting, S. T. M. (2019). Small non-coding RNA transcriptome signatures of chondrocyte ageing. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A30). Retrieved from https://www.webofscience.com/
Smagul, A., Simpson, D., Tew, S., & Peffers, M. J. (2019). The articular cartilage proteome is dependent on zone, age and disease state. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A36). Retrieved from https://www.webofscience.com/
2018
Identification of synovial fluid proteins that are associated with early osteoarthritis treatment failure: the search for novel markers leads us back to matrix metalloproteinases (MMPs) (Conference Paper)
Hulme, C. H., Wilson, E., Fuller, H. R., Roberts, S., Richardson, J. B., Gallacher, P., . . . Wright, K. T. (2018). Identification of synovial fluid proteins that are associated with early osteoarthritis treatment failure: the search for novel markers leads us back to matrix metalloproteinases (MMPs). In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 99 (pp. A2). Retrieved from https://www.webofscience.com/
Mueller-Breckenridge, A. J., Turlo, A. J., Zamboulis, D., Peffers, M. J., & Clegg, P. D. (2018). Insulin-like growth factor binding protein (Igfbp6) is a cross-species transcriptomic tendon marker. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 99 (pp. A2-A3). Retrieved from https://www.webofscience.com/
Anderson, J., Chokesuwattanaskul, S., Phelan, M., Welting, T., Lian, L. Y., Peffers, M., & Wright, H. L. (2018). 1H NMR metabolomics identifies underlying inflammatory pathology in osteoarthritis and rheumatoid arthritis synovial joints. Journal of Proteome Research, 17(11), 3780-3790. doi:10.1021/acs.jproteome.8b00455DOI: 10.1021/acs.jproteome.8b00455
Kemp, G. J., Jackson, M. J., Mccloskey, E. V., & Mathers, J. C. (2018). Towards a toolkit for the assessment and monitoring of musculoskeletal ageing. AGE AND AGEING, 47(6), 774-777. doi:10.1093/ageing/afy078DOI: 10.1093/ageing/afy078
Kemp, G. J., Birrell, F., Clegg, P. D., Cuthbertson, D. J., De Vito, G., van Dieen, J. H., . . . Mathers, J. C. (2018). Developing a toolkit for the assessment and monitoring of musculoskeletal ageing. AGE AND AGEING, 47(suppl_4), iv1-iv19. doi:10.1093/ageing/afy143DOI: 10.1093/ageing/afy143
Stratifying osteoarthritis using liquid chromatography‐tandem mass spectrometry proteomic analysis of synovial fluid (2018). In Equine Veterinary Journal Vol. 50 (pp. 26-27). Wiley. doi:10.1111/evj.48_13008DOI: 10.1111/evj.48_13008
Anderson, J. R., Phelan, M. M., Clegg, P. D., Peffers, M. J., & Rubio-Martinez, L. M. (2018). Synovial Fluid Metabolites Differentiate between Septic and Nonseptic Joint Pathologies. Journal of Proteome Research, 17(8), 2735-2743. doi:10.1021/acs.jproteome.8b00190DOI: 10.1021/acs.jproteome.8b00190
Hulme, C. H., Wilson, E. L., Fuller, H. R., Roberts, S., Richardson, J. B., Gallacher, P., . . . Wright, K. T. (2018). Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation. ARTHRITIS RESEARCH & THERAPY, 20. doi:10.1186/s13075-018-1573-4DOI: 10.1186/s13075-018-1573-4
Peffers, M. J., Balaska, P., Dyers, P., Welting, T., & Cremers, A. (2018). A ROLE FOR SMALL NUCLEOLAR RNA HOST GENES IN CARTILAGE AGEING AND OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S160-S161). doi:10.1016/j.joca.2018.02.349DOI: 10.1016/j.joca.2018.02.349
Peffers, M. J., Ripmeester, E., Caron, M., Steinbusch, M., Balaskas, P., Cremers, A., . . . Welting, T. J. (2018). A ROLE FOR THE SNORNA U3 IN THE ALTERED TRANSLATIONAL CAPACITY OF AGEING AND OSTEOARTHRITIC CHONDROCYTES. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S45-S46). doi:10.1016/j.joca.2018.02.106DOI: 10.1016/j.joca.2018.02.106
Hulme, C. H., Wilson, E. L., Fuller, H. R., Roberts, S. R., Richardson, J. B., Gallacher, P., . . . Wright, K. T. (2018). ACUTE PHASE RESPONSE SIGNALLING IS ALTERED FOLLOWING CARTILAGE HARVEST IN NON-RESPONDERS TO AUTOLOGOUS CHONDROCYTE IMPLANTATION. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S167). doi:10.1016/j.joca.2018.02.363DOI: 10.1016/j.joca.2018.02.363
Peffers, M. J., Balaska, P., Fang, Y., Anderson, J., Burke, K., & Welting, T. (2018). COMPREHENSIVE EXPRESSION ANALYSIS OF SMALL NON CODING RNAS IN EARLY OSTEOARTHRITIS SYNOVIAL FLUID. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S186-S187). doi:10.1016/j.joca.2018.02.401DOI: 10.1016/j.joca.2018.02.401
DEFINING THE ROLE AND MECHANISMS OF MICRORNAS IN CARTILAGE AGEING AND DISEASE (Conference Paper)
Balaskas, P., Goljanek-Whysall, K., Clegg, P., Welting, T., & Peffers, M. (2018). DEFINING THE ROLE AND MECHANISMS OF MICRORNAS IN CARTILAGE AGEING AND DISEASE. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S165). doi:10.1016/j.joca.2018.02.360DOI: 10.1016/j.joca.2018.02.360
IDENTIFICATION OF TISSUE-SPECIFIC BIOMARKERS IN KNEE OSTEOARTHRITIS SYNOVIAL FLUID: A PROTEOMIC APPROACH (Conference Paper)
Timur, U., Jahr, H., Emans, P., van Rhijn, L., Peffers, M., & Welting, T. (2018). IDENTIFICATION OF TISSUE-SPECIFIC BIOMARKERS IN KNEE OSTEOARTHRITIS SYNOVIAL FLUID: A PROTEOMIC APPROACH. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S42). doi:10.1016/j.joca.2018.02.100DOI: 10.1016/j.joca.2018.02.100
McDermott, B. T., Peffers, M. J., McDonagh, B., & Tew, S. R. (2018). RIBOSOMAL PROFILING AND SECRETOME ANALYSIS IDENTIFY THAT INTERLEUKIN-1B DRIVEN CYTOKINE/CHEMOKINE RELEASE FROM CHONDROCYTIC CELLS IS UNDERPINNED BY DIFFERENTIAL TRANSLATION. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S105). doi:10.1016/j.joca.2018.02.228
Anderson, J. R., Clegg, P. D., Rubio-Martinez, L. M., Riggs, C. M., & Peffers, M. J. (2018). STRATIFYING OSTEOARTHRITIS USING LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY PROTEOMIC ANALYSIS OF SYNOVIAL FLUID. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S171). doi:10.1016/j.joca.2018.02.372DOI: 10.1016/j.joca.2018.02.372
Smagul, A., Tew, S., & Peffers, M. J. (2018). THE EFFECT OF U3 SNORNA KNOCKDOWN ON THE CHONDROCYTE PROTEOME. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S165). doi:10.1016/j.joca.2018.02.359DOI: 10.1016/j.joca.2018.02.359
Caron, M. M., Derks, K. W., Sanderink, L., van Rhijn, L. W., Peffers, M. J., & Welting, T. J. (2018). THE GATE TO CONTROLLING CHONDROGENIC DIFFERENTIATION: TRANSCRIPTIONAL REGULATION BY SOX9 IN ATDC5 CELLS. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S109). doi:10.1016/j.joca.2018.02.238DOI: 10.1016/j.joca.2018.02.238
Bardell, D., Peffers, M. J., Clegg, P. D., Molloy, A. P., & Goljanek-Whysall, K. (2018). THE ROLE OF MICRORNAS IN TENDON DYSFUNCTION. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S165-S166). doi:10.1016/j.joca.2018.02.361DOI: 10.1016/j.joca.2018.02.361
Steinbusch, M. M., Caroni, M. M., Surtel, D. A., van Dijk, P. J., Friedrich, F., Zabel, B., . . . Welting, T. J. (2018). VIPERIN REGULATES CHONDROGENIC DIFFERENTIATION VIA CXCL10 PROTEIN SECRETION. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S93). doi:10.1016/j.joca.2018.02.200DOI: 10.1016/j.joca.2018.02.200
Martins, M. C., Peffers, M. J., Lee, K., & Rubio-Martinez, L. M. (2018). Effects of stanozolol on normal and IL-1β-stimulated equine chondrocytes in vitro. BMC VETERINARY RESEARCH, 14. doi:10.1186/s12917-018-1426-zDOI: 10.1186/s12917-018-1426-z
Proteomic analysis of equine plasma and peritoneal fluid in strangulating small intestinal disease (Journal article)
Bardell, D. A., Peffers, M. J., & Milner, P. I. (n.d.). Proteomic analysis of equine plasma and peritoneal fluid in strangulating small intestinal disease. The FASEB Journal.
McIlwraith, C. W., Kawcak, C. E., Frisbie, D. D., Little, C. B., Clegg, P. D., Peffers, M. J., . . . Kraus, V. B. (2018). Biomarkers for equine joint injury and osteoarthritis. JOURNAL OF ORTHOPAEDIC RESEARCH, 36(3), 823-831. doi:10.1002/jor.23738DOI: 10.1002/jor.23738
Peffers, M. J., Balaskas, P., & Smagul, A. (2018). Osteoarthritis year in review 2017: genetics and epigenetics. OSTEOARTHRITIS AND CARTILAGE, 26(3), 304-311. doi:10.1016/j.joca.2017.09.009DOI: 10.1016/j.joca.2017.09.009
Bardell, D. A., Peffers, M. J., Clegg, P. D., Molloy, A., & Whysall, K. A. (n.d.). The role of microRNA:target interactions in tendon dysfunction. Osteoarthritis and Cartilage.
Turlo, A. J., Kharaz, Y. A., Clegg, P. D., Anderson, J., & Peffers, M. J. (2018). Donor age affects proteome composition of tenocyte-derived engineered tendon. BMC BIOTECHNOLOGY, 18. doi:10.1186/s12896-018-0414-5DOI: 10.1186/s12896-018-0414-5
Proteomic Analysis of Equine Plasma and Peritoneal Fluid in Strangulating Small Intestinal Disease (Conference Paper)
Bardell, D., Peffers, M. J., & Milner, P. (2018). Proteomic Analysis of Equine Plasma and Peritoneal Fluid in Strangulating Small Intestinal Disease. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/
Anderson, J. R., Chokesuwattanaskul, S., Phelan, M. P., Welting, T. J. M., Lian, L. -Y., Peffers, M. J., & Wright, H. L. (2018). SYNOVIAL FLUID METABOLITE PROFILES DIFFER BETWEEN OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS. In RHEUMATOLOGY Vol. 57. Retrieved from https://www.webofscience.com/
2017
Rubio Martinez, L. M., Rioja, E., Castro Martins, M., Wipawee, S., Clegg, P., & Peffers, M. J. (2017). Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro. Arthritis Research and Therapy. doi:10.1186/s12917-017-1244-8DOI: 10.1186/s12917-017-1244-8
Rubio-Martinez, L. M., Rioja, E., Martins, M. C., Wipawee, S., Clegg, P., & Peffers, M. J. (2017). Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro. BMC VETERINARY RESEARCH, 13. doi:10.1186/s12917-017-1244-8DOI: 10.1186/s12917-017-1244-8
Pease, L. I., Clegg, P. D., Proctor, C. J., Shanley, D. J., Cockell, S. J., & Peffers, M. J. (2017). Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females. Scientific Reports, 7. doi:10.1038/s41598-017-14650-zDOI: 10.1038/s41598-017-14650-z
Balaskas, P., Goljanek-Whysall, K., Clegg, P., Fang, Y., Cremers, A., Emans, P., . . . Peffers, M. (2017). MicroRNA Profiling in Cartilage Ageing. INTERNATIONAL JOURNAL OF GENOMICS, 2017. doi:10.1155/2017/2713725DOI: 10.1155/2017/2713725
Wardle, R., Pullman, J. A., Haldenby, S., Ressel, L., Pope, M., Clegg, P. D., . . . Peffers, M. J. (2017). Identification of Equid herpesvirus 2 in tissue-engineered equine tendon.. Wellcome open research, 2, 60. doi:10.12688/wellcomeopenres.12176.2DOI: 10.12688/wellcomeopenres.12176.2
Mueller, A. J., Peffers, M. J., Proctor, C. J., & Clegg, P. D. (2017). Systems Approaches in Osteoarthritis: Identifying Routes to Novel Diagnostic and Therapeutic Strategies. JOURNAL OF ORTHOPAEDIC RESEARCH, 35(8), 1573-1588. doi:10.1002/jor.23563DOI: 10.1002/jor.23563
Ashraf Kharaz, Y., Zamboulis, D., Sander, K., Comerford, E., Clegg, P., & Peffers, M. (2017). Comparison between chaotropic and detergent-based sample preparation workflow in tendon for mass spectrometry analysis. Proteomics, 17(13-14). doi:10.1002/pmic.201700018DOI: 10.1002/pmic.201700018
Hulme, C. H., Wilson, E. L., Peffers, M. J., Peffers, M. J., Fuller, H., Roberts, S., . . . Wright, K. T. (2017). POOR CLINICAL RESPONSE TO AUTOLOGOUS CHONDROCYTE IMPLANTATION IS ASSOCIATED WITH A UNIQUE SYNOVIAL FLUID PROTEOME PROFILE. In OSTEOARTHRITIS AND CARTILAGE Vol. 25 (pp. S92). doi:10.1016/j.joca.2017.02.146DOI: 10.1016/j.joca.2017.02.146
Hulme, C. H., Wilson, E. L., Peffers, M. J., Roberts, S., Simpson, D. M., Richardson, J. B., . . . Wright, K. T. (2017). Autologous chondrocyte implantation-derived synovial fluids display distinct responder and non-responder proteomic profiles. Arthritis Research and Therapy, 19. doi:10.1186/s13075-017-1336-7DOI: 10.1186/s13075-017-1336-7
Davidson, R., Gardner, S., Jupp, O., Bullough, A., Butters, S., Watts, L., . . . Clark, I. (2017). Isothiocyanates are detected in human synovial fluid following broccoli consumption and can affect the tissues of the knee joint. Scientific Reports, 7. doi:10.1038/s41598-017-03629-5DOI: 10.1038/s41598-017-03629-5
Turlo, A. J., Kharaz, Y. A., Clegg, P. D., Anderson, J., & Peffers, M. J. (2017). THE EFFECT OF DONOR AGE ON ENGINEERED TENDON TISSUE DERIVED FROM TENOCYTES AND MESENCHYMAL STEM CELLS. In OSTEOARTHRITIS AND CARTILAGE Vol. 25 (pp. S88). doi:10.1016/j.joca.2017.02.137DOI: 10.1016/j.joca.2017.02.137
Peffers, M., Jones, A. R., McCabe, A., & Anderson, J. (2017). Neopeptide Analyser: A software tool for neopeptide discovery in proteomics data.. Wellcome open research, 2, 24. doi:10.12688/wellcomeopenres.11275.1DOI: 10.12688/wellcomeopenres.11275.1
Peffers, M. J. (2017). YEAR IN REVIEW - GENETICS/GENOMICS AND EPIGENETICS. In OSTEOARTHRITIS AND CARTILAGE Vol. 25 (pp. S7). doi:10.1016/j.joca.2017.02.026
Steinbusch, M. M. F., Fang, Y., Milner, P. I., Clegg, P. D., Young, D. A., Welting, T. J. M., & Peffers, M. J. (2017). Serum snoRNAs as biomarkers for joint ageing and post traumatic osteoarthritis. Scientific reports, 7, 11 pages. doi:10.1038/srep43558DOI: 10.1038/srep43558
2016
Kharaz, Y. A., Zamboulis, D., Sanders, K., Comerford, E., Clegg, P., & Peffers, M. (2016). Comparison of protein extraction methods in tendon for mass spectrometry analysis. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 97 (pp. A26). Retrieved from https://www.webofscience.com/
Comparison of protein extraction methods in tendon for mass spectrometry analysis (Conference Paper)
Ashraf Kharaz, Y., Zamboulis, D., Sander, K., Comerford, E., Clegg, P., & Peffers, M. (2016). Comparison of protein extraction methods in tendon for mass spectrometry analysis. In International Journal of Experimental Pathology Vol. 9 (pp. A26). Chester University.
Peffers, M. J., Collins, J., Loughlin, J., proctor, C., & Clegg, P. (2016). A proteomic analysis of chondrogenic, osteogenic and tenogenic constructs from ageing mesenchymal stem cells. Stem Cell Research & Therapy. doi:10.1186/s13287-016-0384-2DOI: 10.1186/s13287-016-0384-2
Peffers, M. J., Goljanek-Whysall, K., Collins, J., Fang, Y., Rushton, M., Loughlin, J., . . . Clegg, P. D. (2016). Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq. PLOS ONE, 11(8). doi:10.1371/journal.pone.0160517DOI: 10.1371/journal.pone.0160517
Proteomic differences between native and tissue-engineered tendon and ligament (Journal article)
Kharaz, Y. A., Tew, S. R., Peffers, M., Canty-Laird, E. G., & Comerford, E. (2016). Proteomic differences between native and tissue-engineered tendon and ligament. PROTEOMICS, 16(10), 1547-1556. doi:10.1002/pmic.201500459DOI: 10.1002/pmic.201500459
Peffers, M. J., Clegg, P. D., Boothroyd, E., Cremer, A., Durtel, D. A., Caron, M. M., & Welting, T. J. (2016). BIG TASKS FOR SMALL RNAS; A NEW CLASS OF RNAS IN THE PATHGENESIS OF OSTEARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 24 (pp. S372). doi:10.1016/j.joca.2016.01.665
DO BIOACTIVE COMPOUNDS FROM CRUCIFEROUS VEGETABLES REACH THE KNEE JOINT? (Conference Paper)
Davidson, R. K., Gardner, S., Jupp, O., Bullough, A., Butters, S., Watts, L., . . . Clark, I. M. (2016). DO BIOACTIVE COMPOUNDS FROM CRUCIFEROUS VEGETABLES REACH THE KNEE JOINT?. In OSTEOARTHRITIS AND CARTILAGE Vol. 24 (pp. S459). doi:10.1016/j.joca.2016.01.838DOI: 10.1016/j.joca.2016.01.838
Peffers, M. J., Milner, P. M., Fang, Y., Young, D., Whysall, K., & Clegg, P. D. (2016). IDENTIFICATION OF SERUM SNORNAS AS BIOMARKERS OF MUSCULOSKELETAL AGEING AND DISEASE. In OSTEOARTHRITIS AND CARTILAGE Vol. 24 (pp. S41-S42). doi:10.1016/j.joca.2016.01.099
THE ROLE OF MICRORNAS IN OSTEOARTHRITIS AND AGEING RELATED FUNCTIONAL DECLINE IN JOINT TISSUE HOMEOSTASIS. (Conference Paper)
House, L., Bou-Gharios, G., Peffers, M., Milner, P., Clegg, P. D., Young, D. A., & Whysall, K. A. (2016). THE ROLE OF MICRORNAS IN OSTEOARTHRITIS AND AGEING RELATED FUNCTIONAL DECLINE IN JOINT TISSUE HOMEOSTASIS.. In OSTEOARTHRITIS AND CARTILAGE Vol. 24 (pp. S63-S64). doi:10.1016/j.joca.2016.01.141DOI: 10.1016/j.joca.2016.01.141
Peffers, M. J., Collins, J., Fang, Y., Goljanek-Whysall, K., Rushton, M., Loughlin, J., . . . Clegg, P. D. (2016). AGE-RELATED CHANGES IN MESENCHYMAL STEM CELLS IDENTIFIED USING A MULTI-OMICS APPROACH. EUROPEAN CELLS & MATERIALS, 31, 136-159. doi:10.22203/eCM.v031a10DOI: 10.22203/eCM.v031a10
Thorpe, C. T., Peffers, M. J., Simpson, D., Halliwell, E., Screen, H. R. C., & Clegg, P. D. (2016). Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition. Scientific Reports, 6. doi:10.1038/srep20455DOI: 10.1038/srep20455
A role for small nucleolar RNAs in musculoskeletal ageing and osteoarthritis (Conference Paper)
Peffers, M., Steinbusch, M., Milner, P., Fang, Y., Young, D., Welting, T., & Clegg, P. (2016). A role for small nucleolar RNAs in musculoskeletal ageing and osteoarthritis. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 97 (pp. A11). Retrieved from https://www.webofscience.com/
Characterization of Neopeptides in Equine Articular Cartilage Degradation (Journal article)
Peffers, M. J., Thornton, D. J., & Clegg, P. D. (2016). Characterization of Neopeptides in Equine Articular Cartilage Degradation. JOURNAL OF ORTHOPAEDIC RESEARCH, 34(1), 106-120. doi:10.1002/jor.22963DOI: 10.1002/jor.22963
Influence of Ageing on Tendon Homeostasis (Journal article)
Birch, H. L., Peffers, M. J., & Clegg, P. D. (2016). Influence of Ageing on Tendon Homeostasis. METABOLIC INFLUENCES ON RISK FOR TENDON DISORDERS, 920, 247-260. doi:10.1007/978-3-319-33943-6_24DOI: 10.1007/978-3-319-33943-6_24
2015
Peffers, M., McDermott, B., Clegg, P., & Riggs, C. (2015). Comprehensive protein profiling of synovial fluid in osteoarthritis following protein equalization. Osteoarthritis and Cartilage, 23(7), 1204-1213. doi:10.1016/j.joca.2015.03.019DOI: 10.1016/j.joca.2015.03.019
Peffers, M. J., Fang, Y., Cheung, K., Wei, T. K. J., Clegg, P. D., & Birch, H. L. (2015). Transcriptome analysis of ageing in uninjured human Achilles tendon. ARTHRITIS RESEARCH & THERAPY, 17. doi:10.1186/s13075-015-0544-2DOI: 10.1186/s13075-015-0544-2
2014
Tew, S., McDermott, B., Fentem, R. B., Peffers, M., & Clegg, P. (2014). Transcriptome‐Wide Analysis of Messenger RNA Decay in Normal and Osteoarthritic Human Articular Chondrocytes. Arthritis and Rheumatology, 66(11), 3052-3061. doi:10.1002/art.38849DOI: 10.1002/art.38849
Peffers, M., Thorpe, C., Collins, J., Eong, R., Wei, T., Screen, H., & Clegg, P. (2014). Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation. The Journal of Biological Chemistry, 289(37), 25867-25878. doi:10.1074/jbc.M114.566554DOI: 10.1074/jbc.M114.566554
Matrix assisted laser desorption ionization mass spectrometry imaging identifies markers of ageing and osteoarthritic cartilage (Journal article)
Peffers, M. J., Cillero-Pastor, B., Eijkel, G. B., Clegg, P. D., & Heeren, R. M. A. (2014). Matrix assisted laser desorption ionization mass spectrometry imaging identifies markers of ageing and osteoarthritic cartilage. Arthritis Research and Therapy, 16. doi:10.1186/ar4560DOI: 10.1186/ar4560
Under pressure: the cell's response (Conference Paper)
Under pressure: the cell's response (2014). In International Journal of Experimental Pathology Vol. 95. Wiley. doi:10.1111/iep.12078DOI: 10.1111/iep.12078
COMPREHENSIVE PROTEIN PROFILING OF SYNOVIAL FLUID IN OSTEOARTHRITIS (Conference Paper)
Peffers, M. J., McDermott, B. T., Riggs, C. M., & Clegg, P. D. (2014). COMPREHENSIVE PROTEIN PROFILING OF SYNOVIAL FLUID IN OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S65-S66). doi:10.1016/j.joca.2014.02.134DOI: 10.1016/j.joca.2014.02.134
POST 'TRANSCRIPTIONAL GENE REGULATION IN AGEING CARTILAGE AND CHONDROCYTES (Conference Paper)
Peffers, M. J., Fentom, R., Tew, S. R., & Clegg, P. D. (2014). POST 'TRANSCRIPTIONAL GENE REGULATION IN AGEING CARTILAGE AND CHONDROCYTES. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S62-S63). doi:10.1016/j.joca.2014.02.128DOI: 10.1016/j.joca.2014.02.128
Biosynthetic alterations in collagen production in ruptured canine anterior cruciate ligament (Conference Paper)
Williamson, K. A., Peffers, M., Pettitt, R., Comerford, E., & Canty-Laird, E. G. (2014). Biosynthetic alterations in collagen production in ruptured canine anterior cruciate ligament. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 95 (pp. A37). Retrieved from https://www.webofscience.com/
Characterisation of neopeptides in articular cartilage identifies novel degradative cleavage sites (Conference Paper)
Peffers, M. J., McKnight, W., & Clegg, P. D. (2014). Characterisation of neopeptides in articular cartilage identifies novel degradative cleavage sites. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 95 (pp. A27-A28). Retrieved from https://www.webofscience.com/
Peffers, M. J., Liu, X., & Clegg, P. D. (2014). Transcriptomic profiling of cartilage ageing.. Genomics data, 2, 27-28. doi:10.1016/j.gdata.2014.03.001DOI: 10.1016/j.gdata.2014.03.001
2013
Absolute Quantification of Selected Proteins in the Human Osteoarthritic Secretome (Journal article)
Peffers, M. J., Beynon, R. J., & Clegg, P. D. (2013). Absolute Quantification of Selected Proteins in the Human Osteoarthritic Secretome. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 14(10), 20658-20681. doi:10.3390/ijms141020658DOI: 10.3390/ijms141020658
Transcriptomic signatures in cartilage ageing (Journal article)
Peffers, M. J., Liu, X., & Clegg, P. D. (2013). Transcriptomic signatures in cartilage ageing. ARTHRITIS RESEARCH & THERAPY, 15(4). doi:10.1186/ar4278DOI: 10.1186/ar4278
AGEING AND OSTEOARTHRITIS MARKERS IDENTIFIED BY MALDI IMAGING MASS SPECTROMETRY (Conference Paper)
Peffers, M. J., Cillero-Pastor, B., Eijkel, G., Clegg, P. D., & Heeren, R. M. (2013). AGEING AND OSTEOARTHRITIS MARKERS IDENTIFIED BY MALDI IMAGING MASS SPECTROMETRY. In OSTEOARTHRITIS AND CARTILAGE Vol. 21 (pp. S63). doi:10.1016/j.joca.2013.02.140DOI: 10.1016/j.joca.2013.02.140
TRANSCRIPTOMIC SIGNATURES IN CARTILAGE AGEING (Conference Paper)
Peffers, M. J., Tew, S. R., & Clegg, P. D. (2013). TRANSCRIPTOMIC SIGNATURES IN CARTILAGE AGEING. In OSTEOARTHRITIS AND CARTILAGE Vol. 21 (pp. S9). doi:10.1016/j.joca.2013.02.040DOI: 10.1016/j.joca.2013.02.040
MALDI imaging mass spectrometry reveals peptide markers of ageing and osteoarthritic cartilage (Conference Paper)
Peffers, M. J., Cillero-Pastor, B., Eijkel, G., Clegg, P. D., & Heeren, R. M. A. (2013). MALDI imaging mass spectrometry reveals peptide markers of ageing and osteoarthritic cartilage. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 94 (pp. A12). Retrieved from https://www.webofscience.com/
Protein signatures of the human osteoarthritic cartilage secretome (Conference Paper)
Peffers, M. J., Beynon, R. J., & Clegg, P. D. (2013). Protein signatures of the human osteoarthritic cartilage secretome. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 94 (pp. A11-A12). Retrieved from https://www.webofscience.com/
Transcriptomic signatures in cartilage ageing (Journal article)
Peffers, M., Liu, X., & Clegg, P. (2013). Transcriptomic signatures in cartilage ageing. Arthritis Research & Therapy, 15(4), R98. doi:10.1186/ar4278DOI: 10.1186/ar4278
2012
PROTEOMIC CHARACTERISATION AND QUANTIFICATION OF AN IN-VITRO EARLY EQUINE OSTEOARTHRITIS MODEL (Conference Paper)
Peffers, M. J., Beynon, R. J., Thornton, D., & Clegg, P. D. (2012). PROTEOMIC CHARACTERISATION AND QUANTIFICATION OF AN IN-VITRO EARLY EQUINE OSTEOARTHRITIS MODEL. In OSTEOARTHRITIS AND CARTILAGE Vol. 20 (pp. S261-S262). doi:10.1016/j.joca.2012.02.439DOI: 10.1016/j.joca.2012.02.439
ABSOLUTE QUANTIFICATION OF CARTILAGE MATRIX PROTEINS (Conference Paper)
Peffers, M. J., Beynon, R. J., Thornton, D. J., & Clegg, P. D. (2012). ABSOLUTE QUANTIFICATION OF CARTILAGE MATRIX PROTEINS. In RHEUMATOLOGY Vol. 51 (pp. 98). Retrieved from https://www.webofscience.com/
2011
Tew, S. R., Vasieva, O., Peffers, M. J., & Clegg, P. D. (2011). Post-transcriptional gene regulation following exposure of osteoarthritic human articular chondrocytes to hyperosmotic conditions. OSTEOARTHRITIS AND CARTILAGE, 19(8), 1036-1046. doi:10.1016/j.joca.2011.04.015DOI: 10.1016/j.joca.2011.04.015
Absolute quantification of the equine early osteoarthritis secretome using QconCAT (Conference Paper)
Peffers, M. J., Beynon, R. J., Thornton, D. J., & Clegg, P. D. (2011). Absolute quantification of the equine early osteoarthritis secretome using QconCAT. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A20-A21). Retrieved from https://www.webofscience.com/
Protein profiling of pathological cartilage (Conference Paper)
Peffers, M. J., Beynon, R. J., Thornton, D. J., & Clegg, P. D. (2011). Protein profiling of pathological cartilage. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A18-A19). Retrieved from https://www.webofscience.com/
2010
Regulation of SOX9 in normal and osteoarthritic equine articular chondrocytes by hyperosmotic loading (Journal article)
Peffers, M. J., Milner, P. I., Tew, S. R., & Clegg, P. D. (2010). Regulation of SOX9 in normal and osteoarthritic equine articular chondrocytes by hyperosmotic loading. OSTEOARTHRITIS AND CARTILAGE, 18(11), 1502-1508. doi:10.1016/j.joca.2010.08.011DOI: 10.1016/j.joca.2010.08.011
CYCLICAL HYPEROSMOLAR LOADING OF HUMAN ARTICULAR CHONDROCYTES INCREASES SOX9 GENE EXPRESSION AND P38 SIGNALLING IS REQUIRED (Conference Paper)
Peffers, M. J., Clegg, P. D., Tew, S., & Milne, P. I. (2010). CYCLICAL HYPEROSMOLAR LOADING OF HUMAN ARTICULAR CHONDROCYTES INCREASES SOX9 GENE EXPRESSION AND P38 SIGNALLING IS REQUIRED. In OSTEOARTHRITIS AND CARTILAGE Vol. 18 (pp. S125). doi:10.1016/S1063-4584(10)60306-8DOI: 10.1016/S1063-4584(10)60306-8
The MEK-ERK signalling pathway plays a role in SOX9 gene expression in human articular chondrocytes (Conference Paper)
Peffers, M. J., Tew, S. R., Milner, P. I., & Clegg, P. D. (2010). The MEK-ERK signalling pathway plays a role in SOX9 gene expression in human articular chondrocytes. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 91 (pp. A38). Retrieved from https://www.webofscience.com/
2009
Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes (Journal article)
Tew, S. R., Peffers, M. J., McKay, T. R., Lowe, E. T., Khan, W. S., Hardingham, T. E., & Clegg, P. D. (2009). Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 297(4), C898-C906. doi:10.1152/ajpcell.00571.2008DOI: 10.1152/ajpcell.00571.2008
