Dr Carl Sheridan PhD
Senior Lecturer in Ocular Cell Transplantation Eye & Vision Sciences
- +44 (0)151 794 9031
- Work email C.Sheridan@liverpool.ac.uk
- Personal Websitehttps://www.researchgate.net/profile/Carl_Sheridan
- ACADEMIAAcademia profile
- ORCID0000-0003-0100-9587
Research
Retinal Pathologies and Treatments
A multidiscipline approach to understand the cellular mechanisms of retinal wound healing which occurs due to a variety of blinding retinal disorders (e.g. Age-related Macular Degeneration, Proliferative Diabetic Retinopathy). A number of projects from bench to beside are continually evolving to enhance our knowledge to combat these blinding conditions.
Cornea and Trabecular Meshwork
Both the corneal endothelium (CE) and trabecular meshwork (TM) cells are special cell types in the eye that do not self-replace when lost in ageing or diseases, such as Fuch’s endothelial dystrophy and primary open angle glaucoma (POAG) (Yu et al., 2015). Understanding the disease mechanisms involved in both cell loss and potential cell replacement approaches are key areas of study within our group.
Research Group Membership
Research Grants
201381564 BILIR
TURKISH EMBASSY (LONDON)
October 2018 - September 2021
Optimisation of PET cell infiltration of trabecular meshwork
INTERNATIONAL GLAUCOMA ASSOCIATION (UK)
July 2016 - February 2019
Investigating the role of microRNAs in glaucoma pathogenesis.
FIGHT FOR SIGHT (UK)
December 2014 - August 2016
Histopathological evaluation of a new therapy for Diabetic retinopathy
DIABETES UK (UK)
August 2007 - January 2008
Research Eye Bank Project
FOUNDATION FOR THE PREVENTION OF BLINDNESS (UK)
September 2012 - July 2017
Research Fellow.
FOUNDATION FOR THE PREVENTION OF BLINDNESS (UK)
October 1998 - September 2002
Development of a New Strategy to Treat Age-Related Macular Degeneration.
FOUNDATION FOR THE PREVENTION OF BLINDNESS (UK)
September 2008 - August 2009
Identification and propagation of stem cell-rich sites of the conjuctiva.
THE GUIDE DOGS FOR THE BLIND ASSOCIATION (UK)
August 2007 - August 2012
ICE of human ocular surface (corneal and conjunctival) stem cells
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
October 2014 - September 2015
Dunhill Research Fellowship: Cell transplantation and the treatment of age-related macular degeneration.
FOUNDATION FOR THE PREVENTION OF BLINDNESS (UK)
August 2001 - January 2005
Micro-Plasma Technology for Controlling Cellular Interactions on Medical Implants
ENGINEERING & PHYSICAL SCIENCES RESEARCH COUNCIL
September 2009 - May 2013
Stem cells for the trabecular meshwork
INTERNATIONAL GLAUCOMA ASSOCIATION (UK)
April 2012 - December 2018
"Smart" targeting of anti-scarring agents in an in vitro model of retinal wound healing.
BRITISH COUNCIL FOR PREV OF BLINDNESS (UK)
December 2003 - November 2009
Endothelial cell and retinal pigment epithelial cell (RPE) interaction in choroidal neovascularization (CNV): action and reaction.
BRITISH COUNCIL FOR PREV OF BLINDNESS (UK)
June 2001 - September 2003
Foundation Research Assistant
FOUNDATION FOR THE PREVENTION OF BLINDNESS (UK)
January 2007 - January 2009
Iris Pigment Epithelial Cell Transplantation and Age Related Macular Degeneration.
FIGHT FOR SIGHT (UK)
October 2002 - September 2005
IPE cell transplantation
THE UNIVERSITY OF HONG KONG (CHINA)🚩
June 2009 - May 2011
Investigation of a new cell treatment for Age-Related Macular Degeneration.
HELP THE AGED
October 2005 - December 2007
Surgical instruments and procedure for cell transplantation in AMD
MACULAR DISEASE SOCIETY (UK)
December 2011 - May 2013
Progenitor cell treatments in Age Related Macular Degeneration (AMD).
DUNHILL MEDICAL TRUST (UK)
January 2006 - December 2009
Transplantation of IPE beneath the neuroretina in ARMD.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
September 2003 - August 2006
Research Collaborations
Dr Wico Lai
External: The University of Hong Kong
Established joint research project
Dr Barry Campbell
Internal
Collaborative grant obtained examining stem cell niches in the conjunctiva
Mr Heinmann
External: Royal Liverpool and Broadgreen University Hospital NHS Trust
Vitroretinal research projects
Professor David Wong
External: The University of Hong Kong
Established and funded collaboration examining retinal diseases
Dr Amy Lo
External: The University of Hong Kong
Lectin conjugation with antimetabolites
Dr Marta Garcia Finana
Internal
Statistical collaboration
Dr T Stappler
External: Royal Liverpool and Broadgreen University Hospital NHS Trust
avastin research, vitreoretinal-surgery-research interaction
Mr Kaye
External: Royal Liverpool and Broadgreen University Hospital NHS Trust
Corneal disease projects
Professor Colm O'Brien
External: University College Dublin, Ireland
Iris pigment epithelial cells in anterior chamber disease
Professor Paul Bishop
External: University of Manchester, UK
Opticin expression in retinopathy
Professor Maria Grant
External: University of Gainesville, USA
Investigating wound healing and neovascularisation in a number of retinopathies.
Dr Ma Long
Internal
Collaborative research project
Mr Pearce
External: Royal Liverpool and Broadgreen University Hospital NHS Trust
Organise mersey Ophthalmology teaching sessions
Richard Cosstick
Internal
Cell specific drug targetting of dedifferentaied retinal pigment epithelial cells
Rachel Williams
Internal
Study of artificial substrates for RPE transplantation