Professor Melita Gordon MD FRCP DTM&H

Professor Clinical Infection, Microbiology & Immunology

Publications

2021

Safety and Efficacy of a Typhoid Conjugate Vaccine in Malawian Children (Journal article)

Patel, P. D., Patel, P., Liang, Y., Meiring, J. E., Misiri, T., Mwakiseghile, F., . . . Team, T. M. (2021). Safety and Efficacy of a Typhoid Conjugate Vaccine in Malawian Children. NEW ENGLAND JOURNAL OF MEDICINE, 385(12), 1104-1115. doi:10.1056/NEJMoa2035916

DOI: 10.1056/NEJMoa2035916

A Bayesian approach for estimating typhoid fever incidence from large-scale facility-based passive surveillance data (Journal article)

Phillips, M. T., Meiring, J. E., Voysey, M., Warren, J. L., Baker, S., Basnyat, B., . . . Grp, S. T. R. A. T. A. A. S. (2021). A Bayesian approach for estimating typhoid fever incidence from large-scale facility-based passive surveillance data. STATISTICS IN MEDICINE. doi:10.1002/sim.9159

DOI: 10.1002/sim.9159

Clofazimine for Treatment of Cryptosporidiosis in Human Immunodeficiency Virus Infected Adults: An Experimental Medicine, Randomized, Double-blind, Placebo-controlled Phase 2a Trial (Journal article)

Tam, P. Y. I., Arnold, S. L. M., Barrett, L. K., Chen, C. R., Conrad, T. M., Douglas, E., . . . Van Voorhis, W. C. (2021). Clofazimine for Treatment of Cryptosporidiosis in Human Immunodeficiency Virus Infected Adults: An Experimental Medicine, Randomized, Double-blind, Placebo-controlled Phase 2a Trial. CLINICAL INFECTIOUS DISEASES, 73(2), 183-191. doi:10.1093/cid/ciaa421

DOI: 10.1093/cid/ciaa421

Diagnostic performance evaluation of hepatitis B e antigen rapid diagnostic tests in Malawi (Journal article)

Stockdale, A. J., Silungwe, N. M., Shawa, I. T., Kreuels, B., Gordon, M. A., & Geretti, A. M. (2021). Diagnostic performance evaluation of hepatitis B e antigen rapid diagnostic tests in Malawi. BMC INFECTIOUS DISEASES, 21(1). doi:10.1186/s12879-021-06134-3

DOI: 10.1186/s12879-021-06134-3

Performance of molecular methods for the detection of Salmonella in human stool specimens (Journal article)

Chirambo, A. C., Nyirenda, T., Jambo, N., Msefula, C., Kamng'ona, A., Molina, S., . . . Gordon, M. (2021). Performance of molecular methods for the detection of Salmonella in human stool specimens. doi:10.12688/wellcomeopenres.16305.2

DOI: 10.12688/wellcomeopenres.16305.2

2020

Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa (Journal article)

Pulford, C., Perez-Sepulveda, B. M., Canals, R., Bevington, J. A., Bengtsson, R. J., Wenner, N., . . . Hinton, J. (2020). Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa. Nature Microbiology. doi:10.1038/s41564-020-00836-1

DOI: 10.1038/s41564-020-00836-1

Electronic data capture for large scale typhoid surveillance, household contact tracing, and health utilisation survey: Strategic Typhoid Alliance across Africa and Asia [version 2; peer review: 2 approved, 2 approved with reservations] (Journal article)

Thindwa, D., Farooq, Y., Shakya, M., Saha, N., Tonks, S., Anokwa, Y., . . . The Strategic Typhoid alliance across Africa and Asia consortium. (2020). Electronic data capture for large scale typhoid surveillance, household contact tracing, and health utilisation survey: Strategic Typhoid Alliance across Africa and Asia [version 2; peer review: 2 approved, 2 approved with reservations]. Wellcome Open Research. doi:10.12688/wellcomeopenres.15811.2

DOI: 10.12688/wellcomeopenres.15811.2

Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets (Journal article)

Wilson, C. N., Pulford, C. V., Akoko, J., Perez Sepulveda, B., Predeus, A. V., Bevington, J., . . . Fevre, E. M. (2020). Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets. PLOS NEGLECTED TROPICAL DISEASES, 14(11). doi:10.1371/journal.pntd.0008796

DOI: 10.1371/journal.pntd.0008796

Sustained Reduction in Third-generation Cephalosporin Usage in Adult Inpatients Following Introduction of an Antimicrobial Stewardship Program in a Large, Urban Hospital in Malawi (Journal article)

Lester, R., Haigh, K., Wood, A., MacPherson, E. E., Maheswaran, H., Bogue, P., . . . Feasey, N. A. (2020). Sustained Reduction in Third-generation Cephalosporin Usage in Adult Inpatients Following Introduction of an Antimicrobial Stewardship Program in a Large, Urban Hospital in Malawi. CLINICAL INFECTIOUS DISEASES, 71(9), E478-E486. doi:10.1093/cid/ciaa162

DOI: 10.1093/cid/ciaa162

Homologous and heterologous re-challenge with Salmonella Typhi and Salmonella Paratyphi A in a randomised controlled human infection model (Journal article)

Gibani, M. M., Jin, C., Shrestha, S., Moore, M., Norman, L., Voysey, M., . . . Pollard, A. J. (2020). Homologous and heterologous re-challenge with Salmonella Typhi and Salmonella Paratyphi A in a randomised controlled human infection model. PLOS NEGLECTED TROPICAL DISEASES, 14(10). doi:10.1371/journal.pntd.0008783

DOI: 10.1371/journal.pntd.0008783

Performance of molecular methods for the detection of Salmonella in human stool specimens (Journal article)

Chirambo, A. C., Nyirenda, T., Jambo, N., Msefula, C., Kamng'ona, A., Molina, S., . . . Gordon, M. (2020). Performance of molecular methods for the detection of Salmonella in human stool specimens. doi:10.12688/wellcomeopenres.16305.1

DOI: 10.12688/wellcomeopenres.16305.1

Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease (Journal article)

Hinton, J., Zhu, X., Owen, S., Gordon, M., & Canals Alvarez, R. (2020). Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease. Proceedings of the National Academy of Sciences of USA, 117(34), 20717-20728. doi:10.1073/pnas.2007472117

DOI: 10.1073/pnas.2007472117

Early Insights From Clinical Trials of Typhoid Conjugate Vaccine (Journal article)

Neuzil, K. M., Basnyat, B., Clemens, J. D., Gordon, M. A., Patel, P. D., Pollard, A. J., . . . Qadri, F. (2020). Early Insights From Clinical Trials of Typhoid Conjugate Vaccine. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71(Supplement_2), S155-S159. doi:10.1093/cid/ciaa370

DOI: 10.1093/cid/ciaa370

The Surveillance for Enteric Fever in Asia Project (SEAP), Severe Typhoid Fever Surveillance in Africa (SETA), Surveillance of Enteric Fever in India (SEFI), and Strategic Typhoid Alliance Across Africa and Asia (STRATAA) Population-based Enteric Fever Studies: A Review of Methodological Similarities and Differences (Journal article)

Carey, M. E., MacWright, W. R., Im, J., Meiring, J. E., Gibani, M. M., Park, S. E., . . . Marks, F. (2020). The Surveillance for Enteric Fever in Asia Project (SEAP), Severe Typhoid Fever Surveillance in Africa (SETA), Surveillance of Enteric Fever in India (SEFI), and Strategic Typhoid Alliance Across Africa and Asia (STRATAA) Population-based Enteric Fever Studies: A Review of Methodological Similarities and Differences. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71(Supplement_2), S102-S110. doi:10.1093/cid/ciaa367

DOI: 10.1093/cid/ciaa367

African Salmonella Typhimurium sequence type 313 lineage 2 evades MAIT cell recognition by overexpressing RibB (Journal article)

Preciado-Llanes, L., Aulicino, A., Canals, R., Moynihan, P., Zhu, X., Jambo, N., . . . Simmons, A. (2020). African Salmonella Typhimurium sequence type 313 lineage 2 evades MAIT cell recognition by overexpressing RibB. Proceedings of the National Academy of Sciences of USA. doi:10.1101/762955

DOI: 10.1101/762955

Intestinal Perforations Associated With a High Mortality and Frequent Complications During an Epidemic of Multidrug-resistant Typhoid Fever in Blantyre, Malawi (Journal article)

Olgemoeller, F., Waluza, J. J., Zeka, D., Gauld, J. S., Diggle, P. J., Read, J. M., . . . Feasey, N. A. (2020). Intestinal Perforations Associated With a High Mortality and Frequent Complications During an Epidemic of Multidrug-resistant Typhoid Fever in Blantyre, Malawi. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71(Supplement_2), S96-S101. doi:10.1093/cid/ciaa405

DOI: 10.1093/cid/ciaa405

Evaluation of a standardised Vi poly-l-lysine ELISA for serology of Vi capsular polysaccharide antibodies (Journal article)

Rigsby, P., Beamish, E., Hockley, J., Atkinson, E., Hitri, K., Jones, E., . . . Grp, A. -V. I. W. (2020). Evaluation of a standardised Vi poly-l-lysine ELISA for serology of Vi capsular polysaccharide antibodies. Biologicals, 66, 21-29. doi:10.1016/j.biologicals.2020.05.002

DOI: 10.1016/j.biologicals.2020.05.002

Electronic data capture for large scale typhoid surveillance, household contact tracing, and health utilisation survey: Strategic Typhoid Alliance across Africa and Asia (Journal article)

Thindwa, D., Farooq, Y., Shakya, M., Saha, N., Tonks, S., Anokwa, Y., . . . The Strategic Typhoid alliance across Africa and Asia consortium. (2020). Electronic data capture for large scale typhoid surveillance, household contact tracing, and health utilisation survey: Strategic Typhoid Alliance across Africa and Asia. doi:10.12688/wellcomeopenres.15811.1

DOI: 10.12688/wellcomeopenres.15811.1

Domestic river water use and risk of typhoid fever: results from a case-control study in Blantyre, Malawi. (Journal article)

Gauld, J. S., Olgemoeller, F., Nkhata, R., Li, C., Chirambo, A., Morse, T., . . . Feasey, N. A. (2020). Domestic river water use and risk of typhoid fever: results from a case-control study in Blantyre, Malawi.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 70(7), 1278-1284. doi:10.1093/cid/ciz405

DOI: 10.1093/cid/ciz405

Increased intracellular survival of Salmonella Typhimurium ST313 in HIV-1-infected primary human macrophages is not associated with Salmonella hijacking the HIV compartment. (Journal article)

Lê-Bury, G., Deschamps, C., Kizilyaprak, C., Blanchard, W., Daraspe, J., Dumas, A., . . . Niedergang, F. (2020). Increased intracellular survival of Salmonella Typhimurium ST313 in HIV-1-infected primary human macrophages is not associated with Salmonella hijacking the HIV compartment.. Biol Cell. doi:10.1111/boc.201900055

DOI: 10.1111/boc.201900055

Performance of molecular methods for the detection of Salmonella in human stool specimens. (Journal article)

Chirambo, A. C., Nyirenda, T. S., Jambo, N., Msefula, C., Kamng'ona, A., Molina, S., . . . Gordon, M. A. (2020). Performance of molecular methods for the detection of Salmonella in human stool specimens. . Wellcome open research, 5, 237. doi:10.12688/wellcomeopenres.16305.1

DOI: 10.12688/wellcomeopenres.16305.1

2019

Distinct climate influences on the risk of typhoid compared to invasive non-typhoid Salmonella disease in Blantyre, Malawi (Journal article)

Thindwa, D., Chipeta, M. G., Henrion, M. Y. R., & Gordon, M. A. (2019). Distinct climate influences on the risk of typhoid compared to invasive non-typhoid Salmonella disease in Blantyre, Malawi. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-56688-1

DOI: 10.1038/s41598-019-56688-1

The fitness landscape of the African Salmonella Typhimurium ST313 strain D23580 reveals unique properties of the pBT1 plasmid (Journal article)

Hinton, J. C. D. (2019). The fitness landscape of the African Salmonella Typhimurium ST313 strain D23580 reveals unique properties of the pBT1 plasmid. PLoS Pathogens, 15(9). doi:10.1371/journal.ppat.1007948

DOI: 10.1371/journal.ppat.1007948

CRYPTOSPORIDIUM DIARRHOEA IN ADULT PATIENTS AT QUEEN ELIZABETH CENTRAL HOSPITAL, BLANTYRE, MALAWI (Conference Paper)

Garg, P., Smith, C., Chirambo, A., Matola, B., Mallewa, J., Hinton, J., & Gordon, M. A. (2019). CRYPTOSPORIDIUM DIARRHOEA IN ADULT PATIENTS AT QUEEN ELIZABETH CENTRAL HOSPITAL, BLANTYRE, MALAWI. In TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE Vol. 113 (pp. S37). Retrieved from http://gateway.webofknowledge.com/

Ascertaining the burden of invasive Salmonella disease in hospitalised febrile children aged under four years in Blantyre, Malawi (Journal article)

Msefula, C. L., Olgemoeller, F., Jambo, N., Segula, D., Tan, T. V., Nyirenda, T. S., . . . Heyderman, R. S. (2019). Ascertaining the burden of invasive Salmonella disease in hospitalised febrile children aged under four years in Blantyre, Malawi. PLOS NEGLECTED TROPICAL DISEASES, 13(7). doi:10.1371/journal.pntd.0007539

DOI: 10.1371/journal.pntd.0007539

On the Ground in Malawi-First Typhoid Conjugate Vaccine Study in Africa (Journal article)

Patel, P., Patel, P., Meiring, J. E., Misiri, T., Mwakiseghile, F., & Gordon, M. A. (2019). On the Ground in Malawi-First Typhoid Conjugate Vaccine Study in Africa. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 100(6), 1299-1300. doi:10.4269/ajtmh.19-0014

DOI: 10.4269/ajtmh.19-0014

The Impact of Vaccination and Prior Exposure on Stool Shedding of Salmonella Typhi and Salmonella Paratyphi in 6 Controlled Human Infection Studies (Journal article)

Gibani, M. M., Voysey, M., Jin, C., Jones, C., Thomaides-Brears, H., Jones, E., . . . Pollard, A. J. (2019). The Impact of Vaccination and Prior Exposure on Stool Shedding of Salmonella Typhi and Salmonella Paratyphi in 6 Controlled Human Infection Studies. CLINICAL INFECTIOUS DISEASES, 68(08), 1265-1273. doi:10.1093/cid/ciy670

DOI: 10.1093/cid/ciy670

Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses. (Journal article)

Napolitani, G., Kurupati, P., Teng, K. W. W., Gibani, M. M., Rei, M., Aulicino, A., . . . Cerundolo, V. (2019). Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.. Nature immunology, 20(4), 514. doi:10.1038/s41590-019-0357-6

DOI: 10.1038/s41590-019-0357-6

Community Engagement Before Initiation of Typhoid Conjugate Vaccine Trial in Schools in Two Urban Townships in Blantyre, Malawi: Experience and Lessons (Journal article)

Meiring, J. E., Sambakunsi, R., Moyo, E., Misiri, T., Mwakiseghile, F., Patel, P., . . . Gordon, M. A. (2019). Community Engagement Before Initiation of Typhoid Conjugate Vaccine Trial in Schools in Two Urban Townships in Blantyre, Malawi: Experience and Lessons. CLINICAL INFECTIOUS DISEASES, 68, S146-S153. doi:10.1093/cid/ciy1110

DOI: 10.1093/cid/ciy1110

Typhoid Vaccine Acceleration Consortium Malawi: A Phase III, Randomized, Double-blind, Controlled Trial of the Clinical Efficacy of Typhoid Conjugate Vaccine Among Children in Blantyre, Malawi (Journal article)

Meiring, J. E., Laurens, M. B., Patel, P., Patel, P., Misiri, T., Simiyu, K., . . . Neuzil, K. M. (2019). Typhoid Vaccine Acceleration Consortium Malawi: A Phase III, Randomized, Double-blind, Controlled Trial of the Clinical Efficacy of Typhoid Conjugate Vaccine Among Children in Blantyre, Malawi. CLINICAL INFECTIOUS DISEASES, 68, S50-S58. doi:10.1093/cid/ciy1103

DOI: 10.1093/cid/ciy1103

Nonspecific effects of oral vaccination with live-attenuated Salmonella Typhi strain Ty21a (Journal article)

Gordon, M. A. (2019). Nonspecific effects of oral vaccination with live-attenuated Salmonella Typhi strain Ty21a. Science Advances, 5(2). doi:10.1126/sciadv.aau6849

DOI: 10.1126/sciadv.aau6849

Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580 (Journal article)

Canals, R., Hammarlöf, D. L., Kröger, C., Owen, S. V., Fong, W. Y., Lacharme-Lora, L., . . . Hinton, J. C. D. (2019). Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580. PLoS Biology, 17(1). doi:10.1371/journal.pbio.3000059

DOI: 10.1371/journal.pbio.3000059

Adding function to the genome of AfricanSalmonellaST313 (Journal article)

Canals, R., Hammarlöf, D., Kröger, C., Owen, S., Fong, W. Y., Lacharme-Lora, L., . . . Hinton, J. (2019). Adding function to the genome of AfricanSalmonellaST313. None (preprint), 17(1). doi:10.1101/450098

DOI: 10.1101/450098

2018

Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets (Journal article)

Aulicino, A., Rue-Albrecht, K. C., Preciado-Llanes, L., Napolitani, G., Ashley, N., Cribbs, A., . . . Simmons, A. (2018). Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets. NATURE COMMUNICATIONS, 9. doi:10.1038/s41467-018-07329-0

DOI: 10.1038/s41467-018-07329-0

Systematic review: the etiology of esophageal squamous cell carcinoma in low-income settings (Journal article)

Chetwood, J. D., Garg, P., Finch, P., & Gordon, M. (2018). Systematic review: the etiology of esophageal squamous cell carcinoma in low-income settings. EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 13(1), 71-88. doi:10.1080/17474124.2019.1543024

DOI: 10.1080/17474124.2019.1543024

Epidemiology of hepatitis B, C and D in Malawi: systematic review (Journal article)

Stockdale, A. J., Mitambo, C., Everett, D., Geretti, A. M., & Gordon, M. A. (2018). Epidemiology of hepatitis B, C and D in Malawi: systematic review. BMC INFECTIOUS DISEASES, 18. doi:10.1186/s12879-018-3428-7

DOI: 10.1186/s12879-018-3428-7

Five-year single-centre experience of carcinoma of the oesophagus from Blantyre, Malawi. (Journal article)

Chetwood, J. D., Finch, P. J., Kankwatira, A., Mallewa, J., Gordon, M. A., & Masamba, L. (2018). Five-year single-centre experience of carcinoma of the oesophagus from Blantyre, Malawi.. BMJ open gastroenterology, 5(1), e000232. doi:10.1136/bmjgast-2018-000232

DOI: 10.1136/bmjgast-2018-000232

Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia (Journal article)

Nyirenda, T. S., Mandala, W. L., Gordon, M. A., & Mastroeni, P. (2018). Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia. MICROBES AND INFECTION, 20(9-10), 589-598. doi:10.1016/j.micinf.2017.11.014

DOI: 10.1016/j.micinf.2017.11.014

Evaluating the safety, tolerability, pharmacokinetics and efficacy of clofazimine in cryptosporidiosis (CRYPTOFAZ): study protocol for a randomized controlled trial (Journal article)

Nachipo, P., Hermann, D., Quinnan, G., Gordon, M. A., Van Voorhis, W. C., & Tam, P. -Y. I. (2018). Evaluating the safety, tolerability, pharmacokinetics and efficacy of clofazimine in cryptosporidiosis (CRYPTOFAZ): study protocol for a randomized controlled trial. TRIALS, 19. doi:10.1186/s13063-018-2846-6

DOI: 10.1186/s13063-018-2846-6

Longevity of duodenal and peripheral T-cell and humoral responses to live-attenuated Salmonella Typhi strain Ty21a (Journal article)

Pennington, S. H., Ferreira, D. M., Reine, J., Nyirenda, T. S., Thompson, A. L., Hancock, C. A., . . . Gordon, M. A. (2018). Longevity of duodenal and peripheral T-cell and humoral responses to live-attenuated Salmonella Typhi strain Ty21a. Vaccine, 36(31), 4725-4733. doi:10.1016/j.vaccine.2018.05.114

DOI: 10.1016/j.vaccine.2018.05.114

Typhoid conjugate vaccines: making vaccine history in Africa (Journal article)

Meiring, J. E., Patel, P., Patel, P., & Gordon, M. A. (2018). Typhoid conjugate vaccines: making vaccine history in Africa. EXPERT REVIEW OF VACCINES, 17(8), 673-676. doi:10.1080/14760584.2018.1496825

DOI: 10.1080/14760584.2018.1496825

Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses (Journal article)

Napolitani, G., Kurupati, P., Teng, K. W. W., Gibani, M. M., Rei, M., Aulicino, A., . . . Cerundolo, V. (2018). Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses. Nature Immunology, 19(7), 742-754. doi:10.1038/s41590-018-0133-z

DOI: 10.1038/s41590-018-0133-z

Role of a single non-coding nucleotide in the evolution of an epidemic African clade of Salmonella (Journal article)

Hammarlof, D., Kröger, C., Owen, S. V., Canals, R., Lacharme-Lora,, L., Wenner, N., . . . Hinton, J. C. D. (2018). Role of a single non-coding nucleotide in the evolution of an epidemic African clade of Salmonella. Proceedings of the National Academy of Sciences of the United States of America, 115(11), E2614-E2623. doi:10.1073/pnas.1714718115

DOI: 10.1073/pnas.1714718115

2017

Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998-2016): a surveillance study (Journal article)

Musicha, P., Cornick, J. E., Bar-Zeev, N., French, N., Masesa, C., Denis, B., . . . Feasey, N. A. (2017). Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998-2016): a surveillance study. LANCET INFECTIOUS DISEASES, 17(10), 1042-1052. doi:10.1016/S1473-3099(17)30394-8

DOI: 10.1016/S1473-3099(17)30394-8

The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine effectiveness study designs: Accelerating the introduction of typhoid conjugate vaccines and reducing the global burden of enteric fever. Report from a meeting held on 26-27 October 2016, Oxford, UK (Journal article)

Meiring, J. E., Gibani, M., Basnyat, B., Bentsi-Enchill, A. D., Clemens, J., Darton, T. C., . . . Grp, T. C. M. (2017). The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine effectiveness study designs: Accelerating the introduction of typhoid conjugate vaccines and reducing the global burden of enteric fever. Report from a meeting held on 26-27 October 2016, Oxford, UK. VACCINE, 35(38), 5081-5088. doi:10.1016/j.vaccine.2017.08.001

DOI: 10.1016/j.vaccine.2017.08.001

The role of a single non-coding nucleotide in the evolution of an epidemic African clade of Salmonella (Journal article)

Hammarlöf, D., Kröger, C., Owen, S., Canals, R., Lora, L. L., Wenner, N., . . . Hinton, J. (2017). The role of a single non-coding nucleotide in the evolution of an epidemic African clade of Salmonella. doi:10.1101/175265

DOI: 10.1101/175265

Loss of Humoral and Cellular Immunity to Invasive Nontyphoidal Salmonella during Current or Convalescent Plasmodium falciparum Infection in Malawian Children (Journal article)

Nyirenda, T. S., Nyirenda, J. T., Tembo, D. L., Storm, J., Dube, Q., Msefula, C. L., . . . Mandala, W. L. (2017). Loss of Humoral and Cellular Immunity to Invasive Nontyphoidal Salmonella during Current or Convalescent Plasmodium falciparum Infection in Malawian Children. CLINICAL AND VACCINE IMMUNOLOGY, 24(7). doi:10.1128/CVI.00057-17

DOI: 10.1128/CVI.00057-17

The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys (Journal article)

Darton, T. C., Meiring, J. E., Tonks, S., Khan, M. A., Khanam, F., Shakya, M., . . . Consortium, S. T. R. A. T. A. A. S. (2017). The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys. BMJ OPEN, 7(6). doi:10.1136/bmjopen-2017-016283

DOI: 10.1136/bmjopen-2017-016283

Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings (vol 48, pg 1211, 2016) (Journal article)

Feasey, N. A., Hadfield, J., Keddy, K. H., Dallman, T. J., Jacobs, J., Deng, X., . . . Thomson, N. R. (2017). Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings (vol 48, pg 1211, 2016). NATURE GENETICS, 49(4), 651. Retrieved from http://gateway.webofknowledge.com/

Impact of maternal antibodies and infant gut microbiota on the immunogenicity of rotavirus vaccines in African, Indian and European infants: protocol for a prospective cohort study (Journal article)

Sindhu, K. N. C., Cunliffe, N., Peak, M., Turner, M., Darby, A., Grassly, N., . . . Kang, G. (2017). Impact of maternal antibodies and infant gut microbiota on the immunogenicity of rotavirus vaccines in African, Indian and European infants: protocol for a prospective cohort study. BMJ OPEN, 7(3). doi:10.1136/bmjopen-2017-016577

DOI: 10.1136/bmjopen-2017-016577

Characterization of the Prophage Repertoire of African Salmonella Typhimurium ST313 Reveals High Levels of Spontaneous Induction of Novel Phage BTP1 (Journal article)

Owen, S. V., Wenner, N., Canals, R., Makumi, A., Hammarlof, D. L., Gordon, M. A., . . . Hinton, J. C. D. (2017). Characterization of the Prophage Repertoire of African Salmonella Typhimurium ST313 Reveals High Levels of Spontaneous Induction of Novel Phage BTP1. FRONTIERS IN MICROBIOLOGY, 8. doi:10.3389/fmicb.2017.00235

DOI: 10.3389/fmicb.2017.00235

2016

Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage (Journal article)

Pennington, S. H., Pojar, S., Mitsi, E., Gritzfeld, J. F., Nikolaou, E., Solorzano, C., . . . Ferreira, D. M. (2016). Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 194(12), 1523-1531. doi:10.1164/rccm.201512-2467OC

DOI: 10.1164/rccm.201512-2467OC

An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid. (Journal article)

Wong, V. K., Baker, S., Connor, T. R., Pickard, D., Page, A. J., Dave, J., . . . International Typhoid Consortium. (2016). An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid.. Nature communications, 7, 12827. doi:10.1038/ncomms12827

DOI: 10.1038/ncomms12827

Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings (Journal article)

Feasey, N. A., Hadfield, J., Keddy, K. H., Dallman, T. J., Jacobs, J., Deng, X., . . . Thomson, N. R. (2016). Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings. Nature Genetics, 48(10), 1211-1217. doi:10.1038/ng.3644

DOI: 10.1038/ng.3644

Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa (Journal article)

Wong, V. K., Holt, K. E., Okoro, C., Baker, S., Pickard, D. J., Marks, F., . . . Consortium, I. T. (2016). Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa. PLOS NEGLECTED TROPICAL DISEASES, 10(9). doi:10.1371/journal.pntd.0004781

DOI: 10.1371/journal.pntd.0004781

Oral Typhoid Vaccination With Live-Attenuated Salmonella Typhi Strain Ty21a Generates Ty21a-Responsive and Heterologous Influenza Virus-Responsive CD4(+) and CD8(+) T Cells at the Human Intestinal Mucosa (Journal article)

Pennington, S. H., Thompson, A. L., Wright, A. K. A., Ferreira, D. M., Jambo, K. C., Wright, A. D., . . . Gordon, M. A. (2016). Oral Typhoid Vaccination With Live-Attenuated Salmonella Typhi Strain Ty21a Generates Ty21a-Responsive and Heterologous Influenza Virus-Responsive CD4(+) and CD8(+) T Cells at the Human Intestinal Mucosa. JOURNAL OF INFECTIOUS DISEASES, 213(11), 1809-1819. doi:10.1093/infdis/jiw030

DOI: 10.1093/infdis/jiw030

SETTING UP AN ENDOSCOPY UNIT IN NORTHERN MALAWI (Conference Paper)

Nyahoda, R., Uledi, S., Kibrete, W., Nyirenda, R., O'Toole, P., Gordon, M. A., & Stanley, A. J. (2016). SETTING UP AN ENDOSCOPY UNIT IN NORTHERN MALAWI. In GUT Vol. 65 (pp. A286). doi:10.1136/gutjnl-2016-312388.537

DOI: 10.1136/gutjnl-2016-312388.537

Bactericidal Immunity to Salmonella in Africans and Mechanisms Causing Its Failure in HIV Infection (Journal article)

Goh, Y. S., Necchi, F., O'Shaughnessy, C. M., Micoli, F., Gavini, M., Young, S. P., . . . MacLennan, C. A. (2016). Bactericidal Immunity to Salmonella in Africans and Mechanisms Causing Its Failure in HIV Infection. PLOS NEGLECTED TROPICAL DISEASES, 10(4). doi:10.1371/journal.pntd.0004604

DOI: 10.1371/journal.pntd.0004604

2015

Mathematical Modeling to Assess the Drivers of the Recent Emergence of Typhoid Fever in Blantyre, Malawi (Journal article)

Pitzer, V. E., Feasey, N. A., Msefula, C., Mallewa, J., Kennedy, N., Dube, Q., . . . Heyderman, R. S. (2015). Mathematical Modeling to Assess the Drivers of the Recent Emergence of Typhoid Fever in Blantyre, Malawi. CLINICAL INFECTIOUS DISEASES, 61, S251-S258. doi:10.1093/cid/civ710

DOI: 10.1093/cid/civ710

Three Epidemics of Invasive Multidrug-Resistant Salmonella Bloodstream Infection in Blantyre, Malawi, 1998-2014 (Journal article)

Feasey, N. A., Masesa, C., Jassi, C., Faragher, E. B., Mallewa, J., Mallewa, M., . . . Gordon, M. A. (2015). Three Epidemics of Invasive Multidrug-Resistant Salmonella Bloodstream Infection in Blantyre, Malawi, 1998-2014. CLINICAL INFECTIOUS DISEASES, 61, S363-S371. doi:10.1093/cid/civ691

DOI: 10.1093/cid/civ691

Interprofessional Education Finding a Place to Start (Journal article)

Gordon, M. A., Lasater, K., Brunett, P., & Dieckmann, N. F. (2015). Interprofessional Education Finding a Place to Start. NURSE EDUCATOR, 40(5), 249-253. doi:10.1097/NNE.0000000000000164

DOI: 10.1097/NNE.0000000000000164

Helicobacter pylori, HIV and Gastric Hypochlorhydria in the Malawian Population (Journal article)

Geraghty, J., Thumbs, A., Kankwatira, A., Andrews, T., Moore, A., Malamba, R., . . . Gordon, M. (2015). Helicobacter pylori, HIV and Gastric Hypochlorhydria in the Malawian Population. PloS One, 10(8). doi:10.1371/journal.pone.0132043

DOI: 10.1371/journal.pone.0132043

Modelling the Contributions of Malaria, HIV, Malnutrition and Rainfall to the Decline in Paediatric Invasive Non-typhoidal Salmonella Disease in Malawi (Journal article)

Feasey, N. A., Everett, D., Faragher, E. B., Roca-Feltrer, A., Kang'ombe, A., Denis, B., . . . Heyderman, R. S. (2015). Modelling the Contributions of Malaria, HIV, Malnutrition and Rainfall to the Decline in Paediatric Invasive Non-typhoidal Salmonella Disease in Malawi. PLOS NEGLECTED TROPICAL DISEASES, 9(7). doi:10.1371/journal.pntd.0003979

DOI: 10.1371/journal.pntd.0003979

Antimicrobial resistance and management of invasive Salmonella disease (Journal article)

Kariuki, S., Gordon, M. A., Feasey, N., & Parry, C. M. (2015). Antimicrobial resistance and management of invasive Salmonella disease. VACCINE, 33, S21-S29. doi:10.1016/j.vaccine.2015.03.102

DOI: 10.1016/j.vaccine.2015.03.102

EVALUATION OF THE IMPACT OF THE LEARNING CONTEXT ON THE ACQUISITION OF COMPLEX PROFESSIONAL SKILLS THROUGH SIMULATION BASED TRAINING COURSES (Conference Paper)

Keane, M. G., Allain, T. J., Mwandumba, H. C., O'Toole, P. A., Gill, D., & Gordon, M. A. (2015). EVALUATION OF THE IMPACT OF THE LEARNING CONTEXT ON THE ACQUISITION OF COMPLEX PROFESSIONAL SKILLS THROUGH SIMULATION BASED TRAINING COURSES. In GUT Vol. 64 (pp. A400-A401). doi:10.1136/gutjnl-2015-309861.880

DOI: 10.1136/gutjnl-2015-309861.880

Global Burden of Invasive Nontyphoidal Salmonella Disease, 2010 (Journal article)

Ao, T. T., Feasey, N. A., Gordon, M. A., Keddy, K. H., Angulo, F. J., & Crump, J. A. (2015). Global Burden of Invasive Nontyphoidal Salmonella Disease, 2010. EMERGING INFECTIOUS DISEASES, 21(6), 941-949. doi:10.3201/eid2106.140999

DOI: 10.3201/eid2106.140999

Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events. (Journal article)

Wong, V. K., Baker, S., Pickard, D. J., Parkhill, J., Page, A. J., Feasey, N. A., . . . Dougan, G. (2015). Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events.. Nature Genetics, 47(06), 632-639. doi:10.1038/ng.3281

DOI: 10.1038/ng.3281

Rapid Emergence of Multidrug Resistant, H58-Lineage Salmonella Typhi in Blantyre, Malawi (Journal article)

Feasey, N. A., Gaskell, K., Wong, V., Msefula, C., Selemani, G., Kumwenda, S., . . . Heyderman, R. S. (2015). Rapid Emergence of Multidrug Resistant, H58-Lineage Salmonella Typhi in Blantyre, Malawi. PLOS NEGLECTED TROPICAL DISEASES, 9(4). doi:10.1371/journal.pntd.0003748

DOI: 10.1371/journal.pntd.0003748

Epidemiology, Clinical Presentation, Laboratory Diagnosis, Antimicrobial Resistance, and Antimicrobial Management of Invasive Salmonella Infections (Journal article)

Crump, J. A., Sjoelund-Karlsson, M., Gordon, M. A., & Parry, C. M. (2015). Epidemiology, Clinical Presentation, Laboratory Diagnosis, Antimicrobial Resistance, and Antimicrobial Management of Invasive Salmonella Infections. CLINICAL MICROBIOLOGY REVIEWS, 28(4), 901-937. doi:10.1128/CMR.00002-15

DOI: 10.1128/CMR.00002-15

2014

Drug Resistance in Salmonella enterica ser. Typhimurium Bloodstream Infection, Malawi (Journal article)

Feasey, N. A., Cain, A. K., Msefula, C. L., Pickard, D., Alaerts, M., Aslett, M., . . . Kingsley, R. A. (2014). Drug Resistance in Salmonella enterica ser. Typhimurium Bloodstream Infection, Malawi. EMERGING INFECTIOUS DISEASES, 20(11), 1957-1959. doi:10.3201/eid2011.141175

DOI: 10.3201/eid2011.141175

Drug resistance in Salmonella enterica ser. Typhimurium bloodstream infection, Malawi. (Journal article)

Feasey, N. A., Cain, A. K., Msefula, C. L., Pickard, D., Alaerts, M., Aslett, M., . . . Kingsley, R. A. (2014). Drug resistance in Salmonella enterica ser. Typhimurium bloodstream infection, Malawi.. Emerging Infectious Diseases, 20(11), 1957-1959.

Sequential Acquisition of T Cells and Antibodies to Nontyphoidal Salmonella in Malawian Children (Journal article)

Nyirenda, T. S., Gilchrist, J. J., Feasey, N. A., Glennie, S. J., Bar-Zeev, N., Gordon, M., . . . Heyderman, R. S. (2014). Sequential Acquisition of T Cells and Antibodies to Nontyphoidal Salmonella in Malawian Children. The Journal of Infectious Diseases, 210(1), 56-64. doi:10.1093/infdis/jiu045

DOI: 10.1093/infdis/jiu045

A Reduction in Adult Blood Stream Infection and Case Fatality at a Large African Hospital following Antiretroviral Therapy Roll-Out (Journal article)

Feasey, N. A., Houston, A., Mukaka, M., Komrower, D., Mwalukomo, T., Tenthani, L., . . . Heyderman, R. S. (2014). A Reduction in Adult Blood Stream Infection and Case Fatality at a Large African Hospital following Antiretroviral Therapy Roll-Out. PLOS ONE, 9(3). doi:10.1371/journal.pone.0092226

DOI: 10.1371/journal.pone.0092226

2013

Salmonella Infections (Chapter)

Feasey, N. A., & Gordon, M. A. (2014). Salmonella Infections. In Manson's Tropical Infectious Diseases (pp. 337-348.e2). Elsevier. doi:10.1016/b978-0-7020-5101-2.00026-1

DOI: 10.1016/b978-0-7020-5101-2.00026-1

Genomic Characterisation of Invasive Non-Typhoidal Salmonella enterica Subspecies enterica Serovar Bovismorbificans Isolates from Malawi (Journal article)

Bronowski, C., Fookes, M. C., Gilderthorp, R., Ashelford, K. E., Harris, S. R., Phiri, A., . . . Winstanley, C. (2013). Genomic Characterisation of Invasive Non-Typhoidal Salmonella enterica Subspecies enterica Serovar Bovismorbificans Isolates from Malawi. PLOS NEGLECTED TROPICAL DISEASES, 7(11). doi:10.1371/journal.pntd.0002557

DOI: 10.1371/journal.pntd.0002557

Genomic characterisation of invasive non-typhoidal Salmonella enterica subspecies enterica Bovismorbificans isolates from Malawi. (Journal article)

Bronowski, C., Fookes, M. C., Gilderthorp, R., Ashelford, K. E., Harris, S., Phiri, A., . . . Winstanley, C. (2013). Genomic characterisation of invasive non-typhoidal Salmonella enterica subspecies enterica Bovismorbificans isolates from Malawi.. PLoS Neglected Tropical Diseases.

Invasive Non-Typhoidal Salmonella Typhimurium ST313 Are Not Host-Restricted and Have an Invasive Phenotype in Experimentally Infected Chickens (Journal article)

Parsons, B. N., Humphrey, S., Salisbury, A. M., Mikoleit, J., Hinton, J. C. D., Gordon, M. A., & Wigley, P. (2013). Invasive Non-Typhoidal Salmonella Typhimurium ST313 Are Not Host-Restricted and Have an Invasive Phenotype in Experimentally Infected Chickens. PLOS NEGLECTED TROPICAL DISEASES, 7(10). doi:10.1371/journal.pntd.0002487

DOI: 10.1371/journal.pntd.0002487

Invasive Non-Typhoidal Salmonella Typhimurium ST313 Are Not Host-Restricted and Have an Invasive Phenotype in Experimentally Infected Chickens (Journal article)

Parsons, B. N., Humphrey, S., Salisbury, A. M., Mikoleit, J., Hinton, J. C. D., Gordon, M. A., & Wigley, P. (n.d.). Invasive Non-Typhoidal Salmonella Typhimurium ST313 Are Not Host-Restricted and Have an Invasive Phenotype in Experimentally Infected Chickens. PLoS Neglected Tropical Diseases, 7(10), e2487. doi:10.1371/journal.pntd.0002487

DOI: 10.1371/journal.pntd.0002487

Salmonella Infections (Chapter)

Feasey, N. A., & Gordon, M. A. (2013). Salmonella Infections. In Lalloo, Farrar, White, Junghauss, Hotez, & Kang (Eds.), Manson's Tropical Diseases (pp. in press). London: Elsevier.

2012

Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa (Journal article)

Okoro, C. K., Kingsley, R. A., Connor, T. R., Harris, S. R., Parry, C. M., Al-Mashhadani, M. N., . . . Dougan, G. (2012). Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa. NATURE GENETICS, 44(11), 1215-1221. doi:10.1038/ng.2423

DOI: 10.1038/ng.2423

Genotypic Homogeneity of Multidrug Resistant S. Typhimurium Infecting Distinct Adult and Childhood Susceptibility Groups in Blantyre, Malawi (Journal article)

Msefula, C. L., Kingsley, R. A., Gordon, M. A., Molyneux, E., Molyneux, M. E., MacLennan, C. A., . . . Heyderman, R. S. (2012). Genotypic Homogeneity of Multidrug Resistant S. Typhimurium Infecting Distinct Adult and Childhood Susceptibility Groups in Blantyre, Malawi. PLOS ONE, 7(7). doi:10.1371/journal.pone.0042085

DOI: 10.1371/journal.pone.0042085

Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa (Journal article)

Feasey, N. A., Dougan, G., Kingsley, R. A., Heyderman, R. S., & Gordon, M. A. (2012). Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa. LANCET, 379(9835), 2489-2499. doi:10.1016/S0140-6736(11)61752-2

DOI: 10.1016/S0140-6736(11)61752-2

High-Resolution Single Nucleotide Polymorphism Analysis Distinguishes Recrudescence and Reinfection in Recurrent Invasive Nontyphoidal Salmonella Typhimurium Disease (Journal article)

Okoro, C. K., Kingsley, R. A., Quail, M. A., Kankwatira, A. M., Feasey, N. A., Parkhill, J., . . . Gordon, M. A. (2012). High-Resolution Single Nucleotide Polymorphism Analysis Distinguishes Recrudescence and Reinfection in Recurrent Invasive Nontyphoidal Salmonella Typhimurium Disease. CLINICAL INFECTIOUS DISEASES, 54(7), 955-963. doi:10.1093/cid/cir1032

DOI: 10.1093/cid/cir1032

Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi. PLOS One 2012, accepted for publication (Journal article)

Msefula, C. L., Kingsley, R. A., Gordon, M. A., Molyneux, E. M., Molyneux, M. E., MacLennan, C. A., . . . Heyderman, R. S. (2012). Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi. PLOS One 2012, accepted for publication. PLOS One.

Nontyphoid Salmonella Disease (Chapter)

Gordon, M. A., Feasey, N. A., & Graham, S. M. (2013). Nontyphoid Salmonella Disease. In Hunter's Tropical Medicine and Emerging Infectious Disease (pp. 462-467). Elsevier. doi:10.1016/b978-1-4160-4390-4.00045-x

DOI: 10.1016/b978-1-4160-4390-4.00045-x

2011

The Human Transcriptome During Nontyphoid Salmonella and HIV Coinfection Reveals Attenuated NF kappa B-Mediated Inflammation and Persistent Cell Cycle Disruption (Journal article)

Schreiber, F., Lynn, D. J., Houston, A., Peters, J., Mwafulirwa, G., Finlay, B. B., . . . Gordon, M. A. (2011). The Human Transcriptome During Nontyphoid Salmonella and HIV Coinfection Reveals Attenuated NF kappa B-Mediated Inflammation and Persistent Cell Cycle Disruption. JOURNAL OF INFECTIOUS DISEASES, 204(8), 1237-1245. doi:10.1093/infdis/jir512

DOI: 10.1093/infdis/jir512

Invasive nontyphoidal Salmonella disease: epidemiology, pathogenesis and diagnosis (Journal article)

Gordon, M. A. (2011). Invasive nontyphoidal Salmonella disease: epidemiology, pathogenesis and diagnosis. CURRENT OPINION IN INFECTIOUS DISEASES, 24(5), 484-489. doi:10.1097/QCO.0b013e32834a9980

DOI: 10.1097/QCO.0b013e32834a9980

Review article: the aetiology, investigation and management of diarrhoea in the HIV-positive patient (Journal article)

Feasey, N. A., Healey, P., & Gordon, M. A. (2011). Review article: the aetiology, investigation and management of diarrhoea in the HIV-positive patient. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 34(6), 587-603. doi:10.1111/j.1365-2036.2011.04781.x

DOI: 10.1111/j.1365-2036.2011.04781.x

Aetiology, investigation and management of diarrhoea in the HIV-positive patient (Journal article)

Feasey, N. A., Healey, P., & Gordon, M. A. (2011). Aetiology, investigation and management of diarrhoea in the HIV-positive patient. Alimentary Pharmacology and Therapeutics, 34, 587-603.

Cholera (Chapter)

Gordon, M. A., & Feasey, N. A. (2011). Cholera. In E. Parry, D. Mabey, & C. Whitty (Eds.), Principles of Medicine in Africa. Cambridge: Cambridge University Press.

Non-typhoidal Salmonella infections (Chapter)

Gordon, M. A., Feasey, N. A., & Graham, S. M. (2011). Non-typhoidal Salmonella infections. In A. Magill, J. Maguire, E. Ryan, & T. Solomon (Eds.), Hunters Tropical Medicine. Oxford: Elsevier.

Typhoid and non-typhoidal Salmonella Infections (Chapter)

Gordon, M. A., & Feasey, N. A. (2011). Typhoid and non-typhoidal Salmonella Infections. In E. Parry, D. Mabey, & C. Whitty (Eds.), Principles of Medicine in Africa. Cambridge: Cambridge University Press.

2010

Typhoid Fever and Invasive Nontyphoid Salmonellosis, Malawi and South Africa (Journal article)

Feasey, N. A., Archer, B. N., Heyderman, R. S., Sooka, A., Dennis, B., Gordon, M. A., & Keddy, K. H. (2010). Typhoid Fever and Invasive Nontyphoid Salmonellosis, Malawi and South Africa. EMERGING INFECTIOUS DISEASES, 16(9), 1448-1451. doi:10.3201/eid1609.100125

DOI: 10.3201/eid1609.100125

Dysregulated Humoral Immunity to Nontyphoidal Salmonella in HIV-Infected African Adults (Journal article)

MacLennan, C. A., Gilchrist, J. J., Gordon, M. A., Cunningham, A. F., Cobbold, M., Goodall, M., . . . Molyneux, M. E. (2010). Dysregulated Humoral Immunity to Nontyphoidal Salmonella in HIV-Infected African Adults. SCIENCE, 328(5977), 508-512. doi:10.1126/science.1180346

DOI: 10.1126/science.1180346

Invasive Non-typhoid Salmonellae Establish Systemic Intracellular Infection in HIV-Infected Adults: An Emerging Disease Pathogenesis (Journal article)

Gordon, M. A., Kankwatira, A. M. K., Mwafulirwa, G., Walsh, A. L., Hopkins, M. J., Parry, C. M., . . . Molyneux, M. E. (2010). Invasive Non-typhoid Salmonellae Establish Systemic Intracellular Infection in HIV-Infected Adults: An Emerging Disease Pathogenesis. CLINICAL INFECTIOUS DISEASES, 50(7), 953-962. doi:10.1086/651080

DOI: 10.1086/651080

2009

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype (Journal article)

Kingsley, R. A., Msefula, C. L., Thomson, N. R., Kariuki, S., Holt, K. E., Gordon, M. A., . . . Dougan, G. (2009). Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype. GENOME RESEARCH, 19(12), 2279-2287. doi:10.1101/gr.091017.109

DOI: 10.1101/gr.091017.109

2008

Invasive salmonellosis in Malawi (Journal article)

Gordon, M. A., & Graham, S. M. (2008). Invasive salmonellosis in Malawi. JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, 2(6), 438-442. Retrieved from http://gateway.webofknowledge.com/

Salmonella infections in immunocompromised adults (Journal article)

Gordon, M. A. (2008). Salmonella infections in immunocompromised adults. JOURNAL OF INFECTION, 56(6), 413-422. doi:10.1016/j.jinf.2008.03.012

DOI: 10.1016/j.jinf.2008.03.012

Epidemics of invasive Salmonella enterica serovar enteritidis and S-enterica serovar typhimurium infection associated with multidrug resistance among adults and children in Malawi (Journal article)

Gordon, M. A., Graham, S. M., Walsh, A. L., Wilson, L., Phiri, A., Molyneux, E., . . . Molyneux, M. E. (2008). Epidemics of invasive Salmonella enterica serovar enteritidis and S-enterica serovar typhimurium infection associated with multidrug resistance among adults and children in Malawi. CLINICAL INFECTIOUS DISEASES, 46(7), 963-969. doi:10.1086/529146

DOI: 10.1086/529146

Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut (Journal article)

Raffatellu, M., Santos, R. L., Verhoeven, D. E., George, M. D., Wilson, R. P., Winter, S. E., . . . Baumler, A. J. (2008). Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut. NATURE MEDICINE, 14(4), 421-428. doi:10.1038/nm1743

DOI: 10.1038/nm1743

Non-typhoid salmonella bacteraemia in Malawian adults (Thesis / Dissertation)

Gordon, M. A. (2008). Non-typhoid salmonella bacteraemia in Malawian adults. (PhD Thesis, The University of Liverpool).

Nontyphoid salmonella disease in Malawi (Journal article)

Gordon, M. A., & Graham, S. M. (2008). Nontyphoid salmonella disease in Malawi. Journal of Infections in Developing Countries, 2, 422-438.

2007

Primary macrophages from HIV-infected adults show dysregulated cytokine responses to Salmonella, but normal internalization and killing (Journal article)

Gordon, M. A., Gordon, S. B., Musaya, L., Zijlstra, E. E., Molyneux, M. E., & Read, R. C. (2007). Primary macrophages from HIV-infected adults show dysregulated cytokine responses to Salmonella, but normal internalization and killing. AIDS, 21(18), 2399-2408. doi:10.1097/QAD.0b013e3282f25107

DOI: 10.1097/QAD.0b013e3282f25107

A lesson in a dish of beans (Journal article)

Gordon, M. A. (2007). A lesson in a dish of beans. British Medical Journal, 335(7609), 45.

2005

A Malawian fisherman with a flail chest (Journal article)

Mwafulirwa, G., Gordon, M. A., Zijlstra, E. E., Kampondeni, S., Mukibi, J. M., Fraser, W. D., & Gordon, S. B. (2005). A Malawian fisherman with a flail chest. Respiratory Medicine Extra, 1(3), 47-48. doi:10.1016/j.rmedx.2005.04.003

DOI: 10.1016/j.rmedx.2005.04.003

Gamma interferon enhances internalization and early nonoxidative killing of Salmonella enterica serovar typhimurium by human macrophages and modifies cytokine responses (Journal article)

Gordon, M. A., Jack, D. L., Dockrell, D. H., Lee, M. E., & Read, R. C. (2005). Gamma interferon enhances internalization and early nonoxidative killing of Salmonella enterica serovar typhimurium by human macrophages and modifies cytokine responses. INFECTION AND IMMUNITY, 73(6), 3445-3452. doi:10.1128/IAI.73.6.3445-3452.2005

DOI: 10.1128/IAI.73.6.3445-3452.2005

2004

Cholera (Chapter)

Gordon, M. A. (2004). Cholera. In G. Parry, & G. Mabey (Eds.), Principles of Medicine in Africa (pp. 1416). Cambridge: Cambridge University Press.

Diarrhoea (Chapter)

Weber, M., & Gordon, M. A. (2004). Diarrhoea. In G. Parry, & G. Mabey (Eds.), Principles of Medicine in Africa (pp. 1). Cambridge: Cambridge University Press.

Non-typhoidal salmonella bacteraemia - an under-recognized feature of AIDS in African adults (Journal article)

Kankwatira, A. M., Mwafulirwa, G. A. K., & Gordon, M. A. (2004). Non-typhoidal salmonella bacteraemia - an under-recognized feature of AIDS in African adults. TROPICAL DOCTOR, 34(4), 198-200. doi:10.1177/004947550403400404

DOI: 10.1177/004947550403400404

Shigella (Chapter)

Gordon, M. A. (2004). Shigella. In G. Parry, & G. Maybey (Eds.), Principles of Medicine in Africa (pp. 1416). Cambridge: Cambridge University Press.

Typhoid and other Salmonella infections (Chapter)

Gordon, M. A. (2004). Typhoid and other Salmonella infections. In G. Parry, & G. Mabey (Eds.), Principles of Medicine in Africa (pp. chapters 48, 49,50). Cambridge: Cambridge University Press.

2003

Schistosomiasis does not contribute to death or recurrence of nontyphoid Salmonella bacteremia in human immunodeficiency virus-infected Malawian adults (Journal article)

Gordon, M. A., Zijlstra, E. E., Naus, C. W. A., Visser, L. G., Molyneux, M. E., & van Lieshout, L. (2003). Schistosomiasis does not contribute to death or recurrence of nontyphoid Salmonella bacteremia in human immunodeficiency virus-infected Malawian adults. CLINICAL INFECTIOUS DISEASES, 37(12), E177-E179. doi:10.1086/379828

DOI: 10.1086/379828

Non-typhoidal salmonella (NTS) bacteraemia in Malawian adults: a severe, recrudescent, HIV-associated illness (Journal article)

Gordon, M. A., Banda, H. T., Gondwe, M., Gordon, S. B., Walsh, A. L., Phiri, A., . . . Molyneux, M. E. (2003). Non-typhoidal salmonella (NTS) bacteraemia in Malawian adults: a severe, recrudescent, HIV-associated illness. Malawi Medical Journal, 15, 47-51.

Schistosomiasis does not contribute to death or recurrence in HIV-infected Malawian adults with non-typhoid salmonella (NTS) bacteraemia. (Journal article)

Gordon, M. A., Zijlstra, E. E., Naus, C., Molyneux, M. E., Visser, L., & van Lieshout, L. (2003). Schistosomiasis does not contribute to death or recurrence in HIV-infected Malawian adults with non-typhoid salmonella (NTS) bacteraemia.. Clinical Infectious Diseases, 37(12), e177-e179.

2002

Non-typhoidal salmonella bacteraemia among HIV-infected Malawian adults: High mortality and frequent recrudescence (Journal article)

Gordon, M. A., Banda, H. T., Gondwe, M., Gordon, S. B., Boeree, M. J., Walsh, A. L., . . . Molyneux, M. E. (2002). Non-typhoidal salmonella bacteraemia among HIV-infected Malawian adults: High mortality and frequent recrudescence. AIDS, 16(12), 1633-1641. doi:10.1097/00002030-200208160-00009

DOI: 10.1097/00002030-200208160-00009

Pneumococcal disease in HIV-infected Malawian adults: acute mortality and long-term survival (Journal article)

Gordon, S. B., Chaponda, M., Walsh, A. L., Whitty, C. J. M., Gordon, M. A., Machili, C. E., . . . Molyneux, M. E. (2002). Pneumococcal disease in HIV-infected Malawian adults: acute mortality and long-term survival. AIDS, 16(10), 1409-1417. doi:10.1097/00002030-200207050-00013

DOI: 10.1097/00002030-200207050-00013

Are intestinal helminths a risk factor for non-typhoidal Salmonella bacteraemia in adults in Africa who are seropositive for HIV? A case-control study (Journal article)

Dowling, J. J., Whitty, C. J. M., Chaponda, M., Munthali, C., Zijlstra, E. E., Gilks, C. F., . . . Gordon, M. A. (2002). Are intestinal helminths a risk factor for non-typhoidal Salmonella bacteraemia in adults in Africa who are seropositive for HIV? A case-control study. ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 96(2), 203-208. doi:10.1179/000349802125000277

DOI: 10.1179/000349802125000277

Non-typhoidal salmonella bacteraemia among HIV-infected Malawian adults: high mortality and frequent recrudescence (Journal article)

Gordon, M. A., Banda, H. T., Gondwe, M., Gordon, S. B., Boeree, M. J., Walsh, A. L., . . . Molyneux, M. E. (2002). Non-typhoidal salmonella bacteraemia among HIV-infected Malawian adults: high mortality and frequent recrudescence. AIDS, 16(12), 1633-1641.

Pneumococcal disease in HIV-infected Malawian adults: acute mortality and long-term survival. (Journal article)

Gordon, S. B., Chaponda, M., Walsh, A. L., Whitty, C. J., Gordon, M. A., Machili, C. E., . . . Molyneux, M. E. (2002). Pneumococcal disease in HIV-infected Malawian adults: acute mortality and long-term survival.. AIDS, 16(10), 1409-1417.

2001

3 cases of bacteraemia caused by Vibrio cholerae 01 in Blantyre, Malawi. (Journal article)

Gordon, M. A., Walsh, A. L., Rogerson, S. R. K., Magomero, K. C., Machili, C. E., Corkill, J. E., & Hart, C. A. (2001). 3 cases of bacteraemia caused by Vibrio cholerae 01 in Blantyre, Malawi.. Emerging Infectious Diseases, 7(6), 1059-1061. Retrieved from http://www.cdc.gov/ncidod/eid/vol7no6/pdf/gordon.pdf

Bacteraemia and mortality among adult medical admissions in Malawi - Predominance of non-typhi Salmonellae and Streptococcus pneumoniae (Journal article)

Gordon, M. A., Walsh, A. L., Chaponda, M., Soko, D., Mbvwinji, M., Molyneux, M. E., & Gordon, S. B. (2001). Bacteraemia and mortality among adult medical admissions in Malawi - Predominance of non-typhi Salmonellae and Streptococcus pneumoniae. JOURNAL OF INFECTION, 42(1), 44-49. doi:10.1053/jinf.2000.0779

DOI: 10.1053/jinf.2000.0779

Three cases of bacteremia caused by Vibrio cholerae O1 in Blantyre, Malawi (Journal article)

Gordon, M. A., Walsh, A. L., Rogerson, S. R. K., Magomero, K. C., Machili, C. E., Corkill, J. E., & Hart, C. A. (2001). Three cases of bacteremia caused by Vibrio cholerae O1 in Blantyre, Malawi. EMERGING INFECTIOUS DISEASES, 7(6), 1059-1061. doi:10.3201/eid0706.010629

DOI: 10.3201/eid0706.010629

2000

Bacterial meningitis in Malawian adults: Pneumococcal disease is common, severe, and seasonal (Journal article)

Gordon, S. B., Walsh, A. L., Chaponda, M., Gordon, M. A., Soko, D., Mbwvinji, M., . . . Read, R. C. (2000). Bacterial meningitis in Malawian adults: Pneumococcal disease is common, severe, and seasonal. CLINICAL INFECTIOUS DISEASES, 31(1), 53-57. doi:10.1086/313910

DOI: 10.1086/313910

Bacterial meningitis in Malawian adults; Pneumococcal disease is common, severe and seasonal (Journal article)

Gordon, S. B., Walsh, A. L., Chaponda, M., Gordon, M. A., Soko, D., Molyneux, M. E., & Read, R. C. (2000). Bacterial meningitis in Malawian adults; Pneumococcal disease is common, severe and seasonal. Clinical Infectious Diseases, 31, 17-22.

Infections in AIDS: Non-typhoidal salmonellae in AIDS (Journal article)

Hart, C. A., Kariuki, S., Graham, S. M., & Gordon, M. A. (2000). Infections in AIDS: Non-typhoidal salmonellae in AIDS. Journal of Medical Microbiology, 49, 955-957.

1999

Primary biliary cirrhosis shows association with genetic polymorphism of tumour necrosis factor alpha promoter region (Journal article)

Gordon, M. A., Oppenheim, E., Camp, N. J., di Giovine, F. S., Duff, G. W., & Gleeson, D. (1999). Primary biliary cirrhosis shows association with genetic polymorphism of tumour necrosis factor alpha promoter region. JOURNAL OF HEPATOLOGY, 31(2), 242-247. doi:10.1016/S0168-8278(99)80220-7

DOI: 10.1016/S0168-8278(99)80220-7

1996

Interleukin-1 Beta Gene Polymorphism is Associated with Autoimmune Hepatitis (Journal article)

Gordon, M. A., Gleeson, D., Oppenheim, E., Underwood, J., diGiovine, F. S., & Duff, G. W. (1996). Interleukin-1 Beta Gene Polymorphism is Associated with Autoimmune Hepatitis. Clinical Science, 90 sup, 6P.

1995

Association of an Interlekin-1 Beta Gene Variation with Primary Biliary Cirrhosis (Journal article)

Gordon, M. A., Gleeson, D., Oppenheim, E., di Giovine, F. S., & Duff, G. W. (1995). Association of an Interlekin-1 Beta Gene Variation with Primary Biliary Cirrhosis. Gut, 37 sup, A17.

1993

RELAPSES IN PATIENTS WITH A SYSTEMIC VASCULITIS (Journal article)

GORDON, M., LUQMANI, R. A., ADU, D., GREAVES, I., RICHARDS, N., MICHAEL, J., . . . BACON, P. A. (1993). RELAPSES IN PATIENTS WITH A SYSTEMIC VASCULITIS. QUARTERLY JOURNAL OF MEDICINE, 86(12), 779-789. Retrieved from http://gateway.webofknowledge.com/

Necrotising vasculitis - relapse despite cytotoxic therapy (Journal article)

Gordon, M. A., Luqmani, R. A., Adu, D., Greaves, I., Richards, N., Michael, J., . . . Bacon, P. A. (1993). Necrotising vasculitis - relapse despite cytotoxic therapy. Adv Exp Med Biol, 336, 447-481.

Relapses in patients with systemic vasculitis (Chapter)

Gordon, M. A., Luqmani, R., Adu, D., Greaves, I., Richards, N., Michael, J., . . . Bacon, P. A. (1993). Relapses in patients with systemic vasculitis. In W. Gross (Ed.), ANCA-associated vasculitides; immunological and clinical aspects (pp. 0). New York: Plenum Press.