Professor Melita Gordon MD FRCP DTM&H

Professor Clinical Infection, Microbiology & Immunology

Research

Research Interest 1

The pathogenesis of invasive non-typhoidal salmonella infections in HIV.
Gut mucosal immunity in HIV

Research Grants

Impact of maternally derived antibodies and infant microbiota on the immunogenicity of rotavirus vaccines in African, Indian and European infants.

DEPARTMENT FOR BUSINESS, INNOVATION AND SKILLS (UK)

July 2015 - December 2018

Accelerating Availability and Access to Typhoid Conjugate Vaccines (TyVAC)

BILL & MELINDA GATES FOUNDATION (USA)

September 2017 - December 2021

Malawi as a Central African Endoscopy Training Centre

BRITISH SOCIETY OF GASTROENTEROLOGY (UK)

March 2016 - March 2020

Wellcome Trust Clinical PhD Programme 15/16

WELLCOME TRUST (UK)

September 2015 - January 2020

CRYPTPREV Prevalence of cryptosporidium in HIV-infected adults with diarrhea in Blantyre

BILL & MELINDA GATES FOUNDATION (USA)

May 2016 - October 2018

Field testing of diagnostics tool during typhoid outbreak in Malawi

BILL & MELINDA GATES FOUNDATION (USA)

October 2016 - December 2018

A strategic vision to drive the control of enteric fever through vaccination. (STRATSUP)

BILL & MELINDA GATES FOUNDATION (USA), WELLCOME TRUST (UK)

April 2015 - December 2020

Transcriptomic analysis of Salmonella Typhimurium ST313 Lineage 2A

MEDICAL RESEARCH FOUNDATION (UK)

February 2016 - October 2016

iNTS Knowledge Gaps in Transmission, Exposure and Diagnostics.

BILL & MELINDA GATES FOUNDATION (USA)

July 2015 - August 2017

Typhoid Diagnostics for Measuring Disease Burden

BILL & MELINDA GATES FOUNDATION (USA)

March 2016 - February 2017

Partnerships in gastrointestinal endoscopy training and practice - outreach to support district hospitals in Malawi

BRITISH SOCIETY OF GASTROENTEROLOGY (UK)

May 2011 - April 2013

Wellcome Trust Clinical PhD Programme - Philip Burgess

WELLCOME TRUST (UK)

August 2010 - July 2011

Wellcome Trust Clinical PhD Programme: James Scriven

WELLCOME TRUST (UK)

August 2010 - July 2011

Wellcome Trust Postdoctoral Veterinary Research.

WELLCOME TRUST (UK)

September 2014 - February 2015

Undergraduate medical student training in health research: Universities of Malawi and Liverpool

THE NUFFIELD FOUNDATION (UK)

January 2011 - February 2015

SAGE Endoscopy Training

SHIRE PHARMACEUTICALS LIMITED (UK)

August 2012 - July 2017

The impact of travel on antimicrobial resistance in the human gut microbiome – pilot work

DEPARTMENT OF HEALTH & SOCIAL CARE (UK) (DOH/DHSC/NIHR)

April 2011 - July 2012

Developing and delivering a Foundation Course in Endoscopy for the Medical and Surgical trainee curricula of Malawi’s Medical School.

BRITISH SOCIETY OF GASTROENTEROLOGY (UK)

January 2014 - December 2015

Cellular responses to Salmonella vaccination

THE SIR JULES THORN CHARITABLE TRUST (UK)

October 2012 - March 2016

Health priorities in resource-limited settings.

WELLCOME TRUST (UK)

September 2014 - August 2015

Sustainable Partnerships in Gastrointestinal Endoscopy Training and Practice - Outreach to Support District Hospitals in Malawi

BRITISH COUNCIL (UK)

June 2011 - May 2012

Wellcome Trust Clinical PhD Programme.

WELLCOME TRUST (UK)

September 2012 - December 2013

The mechanism of recurrent non-typhi salmonella (NTS) bacteraemia in HIV-I infected Malawian adults.

WELLCOME TRUST (UK)

November 2000 - December 2005

Study of disease mechanisms in enteric fever to characterise innate and adaptive immunity in the mucosa and peripheral blood using controlled human infection

MEDICAL RESEARCH COUNCIL (MRC)

January 2013 - August 2019

Clinical PhD Programme (14/15)

WELLCOME TRUST (UK)

September 2014 - August 2015

Understanding Mucosal Immunity to Typhoid.

THE TERESA ROSENBAUM GOLDEN CHARITABLE TRUST (THE ROSETREES TRUST) (UK)

May 2013 - June 2016

Development of a TTT-trained nurse educator network in Malawi

BRITISH SOCIETY OF GASTROENTEROLOGY (UK)

February 2013 - December 2015

Establishment of natural acquired nontyphoidal salmonella-specific B and T cell immunity in Malawian children

DEPARTMENT FOR INTERNATIONAL DEVELOPMENT (DFID) (UK)

May 2012 - April 2015

Wellcome Trust Clinical PhD Programme - Mathew Kelly

WELLCOME TRUST (UK)

August 2010 - August 2011

Health Priorities in the Developing World

WELLCOME TRUST (UK)

September 2013 - August 2014

Research Collaborations

Dr Stephen Baker

External: The University of Oxford

Collaboration on antimicrobial resistance genes in the healthy gut microbiota

Dr Florence Niedergang

External: Universite Paris Descartes

Collaboration on intracellular Salmonella infections in HIV

Dr David Lynn

External: Teagasc (Irish Agriculture and Food Development Authority)

Collaboration on systems biology analysis of microarray and RNA Seq transcriptomic data, using InnateDB analysis platform

Prof Andreas Baumler

External: University of California, LA

Clinical consultant to NIH exploratory grant, aiming to study the mechanism of invasive non-typhoidal salmonella infections using a simian SIV model

Professor Brett Finlay

External: University of British Columbia, Vancouver, Canada

I am a collaborator on a Gates Grand Challenge programme held by Brett Finlay

Professor Bob Hancock

External: University of British Columbia, Vancouver, Canada

I collaborate with Professor Hancock on a Gates Grand Challenge programme

Prof Gordon Dougan

External: Wellcome Trust Sanger Institute

Study of host RNA responses to non-typhoidal salmonella infection in HIV, using RNA microarray. Molecular epidemiology of Salmonella in Africa

Jill Gilmour

External: Imperial College London

Mucosal immunology in HIV

Prof Robert Heyderman

Internal

Mucosal immunology in HIV, Host response to invasive salmonella disease

Dr CM Parry

Internal

Phenotyping of NTS isolates