Dr Lance Turtle BSc PhD MBBS MRCP DTMH

Senior Clinical Lecturer in Infectious Diseases Clinical Infection, Microbiology & Immunology

    Publications

    2021

    A blood atlas of COVID-19 defines hallmarks of disease severity and specificity (Journal article)

    COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium., Ahern, D., Ai, Z., Ainsworth, M., Allan, C., Allcock, A., . . . Zurke, Y. -X. (2021). A blood atlas of COVID-19 defines hallmarks of disease severity and specificity. doi:10.1101/2021.05.11.21256877

    DOI: 10.1101/2021.05.11.21256877

    T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses (Journal article)

    Ogbe, A., Kronsteiner, B., Skelly, D. T., Pace, M., Brown, A., Adland, E., . . . Oxford, P. T. C. (2021). T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-21856-3

    DOI: 10.1038/s41467-021-21856-3

    Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study (Journal article)

    Gupta, R. K., Harrison, E. M., Ho, A., Docherty, A. B., Knight, S. R., van Smeden, M., . . . Investigators, I. S. A. R. I. C. C. (2021). Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study. LANCET RESPIRATORY MEDICINE, 9(4), 349-359. doi:10.1016/S2213-2600(20)30559-2

    DOI: 10.1016/S2213-2600(20)30559-2

    A haemagglutination test for rapid detection of antibodies to SARS-CoV-2 (Journal article)

    Townsend, A., Rijal, P., Xiao, J., Tan, T. K., Huang, K. -Y. A., Schimanski, L., . . . Joly, E. (2021). A haemagglutination test for rapid detection of antibodies to SARS-CoV-2. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-22045-y

    DOI: 10.1038/s41467-021-22045-y

    Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol (Journal article)

    Sigfrid, L., Drake, T., Pauley, E., Jesudason, E., Olliaro, P., Lim, W. S., . . . ISARIC4C investigators. (2021). Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol. doi:10.1101/2021.03.18.21253888

    DOI: 10.1101/2021.03.18.21253888

    Prospective observational study of SARS-CoV-2 infection, transmission and immunity in a cohort of households in Liverpool City Region, UK (COVID-LIV): a study protocol (Journal article)

    Setiabudi, W., Hungerford, D., Subramaniam, K., Vaselli, N. M., Shaw, V. E., Wilton, M., . . . French, N. (2021). Prospective observational study of SARS-CoV-2 infection, transmission and immunity in a cohort of households in Liverpool City Region, UK (COVID-LIV): a study protocol. BMJ Open, 11(3), e048317. doi:10.1136/bmjopen-2020-048317

    DOI: 10.1136/bmjopen-2020-048317

    Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19. (Journal article)

    Thwaites, R. S., Sanchez Sevilla Uruchurtu, A., Siggins, M. K., Liew, F., Russell, C. D., Moore, S. C., . . . ISARIC4C investigators. (2021). Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19.. Science Immunology, 6(57). doi:10.1126/sciimmunol.abg9873

    DOI: 10.1126/sciimmunol.abg9873

    What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? A harmonised, global longitudinal observational study protocol. (Journal article)

    Sigfrid, L., Cevik, M., Jesudason, E., Lim, W. S., Rello, J., Amuasi, J., . . . Scott, J. T. (2021). What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? A harmonised, global longitudinal observational study protocol.. BMJ Open, 11(3), e043887. doi:10.1136/bmjopen-2020-043887

    DOI: 10.1136/bmjopen-2020-043887

    Genetic mechanisms of critical illness in COVID-19 (Journal article)

    Pairo-Castineira, E., Clohisey, S., Klaric, L., Bretherick, A. D., Rawlik, K., Pasko, D., . . . Investigators, G. -C. (2021). Genetic mechanisms of critical illness in COVID-19. NATURE, 591(7848), 92-+. doi:10.1038/s41586-020-03065-y

    DOI: 10.1038/s41586-020-03065-y

    Comparative evaluation of ten lateral flow immunoassays to detect SARS-CoV-2 antibodies (Journal article)

    Garrod, G., Owen, S., Baillie, K., Baldwin, L., Brown, L., Byrne, R., . . . ISARIC4C Investigators. (2021). Comparative evaluation of ten lateral flow immunoassays to detect SARS-CoV-2 antibodies. doi:10.12688/wellcomeopenres.16522.1

    DOI: 10.12688/wellcomeopenres.16522.1

    Haematological malignancy and nosocomial transmission are associated with an increased risk of death from COVID-19: results of a multi-center UK cohort. (Journal article)

    Bhogal, T., Khan, U. T., Lee, R., Stockdale, A., Hesford, C., Potti-Dhananjaya, V., . . . Palmieri, C. (2021). Haematological malignancy and nosocomial transmission are associated with an increased risk of death from COVID-19: results of a multi-center UK cohort.. Leukemia & lymphoma, 1-16. doi:10.1080/10428194.2021.1876865

    DOI: 10.1080/10428194.2021.1876865

    Guillain-Barre syndrome during the Zika virus outbreak in Northeast Brazil: An observational cohort study (Journal article)

    Leonhard, S. E., Halstead, S., Lant, S. B., de Albuquerque, M. D. F. P. M., de Brito, C. A. A., de Albuquerque, L. B. B., . . . Ferreira, M. L. B. (2021). Guillain-Barre syndrome during the Zika virus outbreak in Northeast Brazil: An observational cohort study. JOURNAL OF THE NEUROLOGICAL SCIENCES, 420. doi:10.1016/j.jns.2020.117272

    DOI: 10.1016/j.jns.2020.117272

    Molecular mechanisms underlying attenuation of live attenuated Japanese encephalitis virus vaccine SA14-14-2 (Journal article)

    Venkatesh, P. H., Kumar, S., Kumar, N., Chaitanya, K., Turtle, L., & Satchidanandam, V. (2021). Molecular mechanisms underlying attenuation of live attenuated Japanese encephalitis virus vaccine SA14-14-2. doi:10.1101/2021.01.14.426643

    DOI: 10.1101/2021.01.14.426643

    2020

    Enterovirus genomic load and disease severity among children hospitalised with hand, foot and mouth disease (Journal article)

    Song, C., Zhou, Y., Li, Y., Liang, L., Turtle, L., Wang, F., . . . Yu, H. (2020). Enterovirus genomic load and disease severity among children hospitalised with hand, foot and mouth disease. EBIOMEDICINE, 62. doi:10.1016/j.ebiom.2020.103078

    DOI: 10.1016/j.ebiom.2020.103078

    Broad and strong memory CD4(+)and CD8(+)T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19 (Journal article)

    Peng, Y., Mentzer, A. J., Liu, G., Yao, X., Yin, Z., Dong, D., . . . Investigators, I. (2020). Broad and strong memory CD4(+)and CD8(+)T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19. NATURE IMMUNOLOGY, 21(11), 1336-1345. doi:10.1038/s41590-020-0782-6

    DOI: 10.1038/s41590-020-0782-6

    Outcomes of COVID-19 related hospitalization among people with HIV in the ISARIC WHO Clinical Characterization Protocol (UK): a prospective observational study. (Journal article)

    Geretti, A. M., Stockdale, A. J., Kelly, S. H., Cevik, M., Collins, S., Waters, L., . . . Semple, M. G. (2020). Outcomes of COVID-19 related hospitalization among people with HIV in the ISARIC WHO Clinical Characterization Protocol (UK): a prospective observational study.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. doi:10.1093/cid/ciaa1605

    DOI: 10.1093/cid/ciaa1605

    A haemagglutination test for rapid detection of antibodies to SARS-CoV-2 (Journal article)

    Townsend, A., Rijal, P., Xiao, J., Tan, T. K., Huang, K. -Y., Schimanski, L., . . . Joly, E. (2020). A haemagglutination test for rapid detection of antibodies to SARS-CoV-2. doi:10.21203/rs.3.rs-91353/v2

    DOI: 10.21203/rs.3.rs-91353/v2

    Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon Antagonism (Journal article)

    Moore, S. C., Penrice-Randal, R., Alruwaili, M., Randle, N., Armstrong, S., Hartley, C., . . . Hiscox, J. A. (2020). Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon Antagonism. VIRUSES-BASEL, 12(10). doi:10.3390/v12101164

    DOI: 10.3390/v12101164

    Development and validation of the 4C Deterioration model for adults hospitalised with COVID-19 (Journal article)

    Gupta, R., Harrison, E., Ho, A., Docherty, A., Knight, S., van Smeden, M., . . . Noursadeghi, M. (2020). Development and validation of the 4C Deterioration model for adults hospitalised with COVID-19. doi:10.1101/2020.10.09.20209957

    DOI: 10.1101/2020.10.09.20209957

    SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus (Journal article)

    Andersson, M., Arancibia-Carcamo, C., Auckland, K., Baillie, K., Barnes, E., Beneke, T., . . . Zambon, M. (2020). SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus. doi:10.12688/wellcomeopenres.16002.2

    DOI: 10.12688/wellcomeopenres.16002.2

    SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus. (Journal article)

    Andersson, M. I., Arancibia-Carcamo, C. V., Auckland, K., Baillie, J. K., Barnes, E., Beneke, T., . . . Zambon, M. (2020). SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus.. Wellcome open research, 5, 181. doi:10.12688/wellcomeopenres.16002.2

    DOI: 10.12688/wellcomeopenres.16002.2

    Neurological disease in adults with Zika and chikungunya virus infection in Northeast Brazil: a prospective observational study (Journal article)

    Brito Ferreira, M. L., Pessoa Militao de Albuquerque, M. D. F., Antunes de Brito, C. A., de Oliveira Franca, R. F., Porto Moreira, A. J., de Morais Machado, M. I., . . . Solomon, T. (2020). Neurological disease in adults with Zika and chikungunya virus infection in Northeast Brazil: a prospective observational study. LANCET NEUROLOGY, 19(10), 826-839. Retrieved from http://gateway.webofknowledge.com/

    Genetic mechanisms of critical illness in Covid-19 (Journal article)

    Pairo-Castineira, E., Clohisey, S., Klaric, L., Bretherick, A., Rawlik, K., Parkinson, N., . . . The Covid-19 Human Genetics Initiative. (2020). Genetic mechanisms of critical illness in Covid-19. doi:10.1101/2020.09.24.20200048

    DOI: 10.1101/2020.09.24.20200048

    Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score. (Journal article)

    Knight, S. R., Ho, A., Pius, R., Buchan, I., Carson, G., Drake, T. M., . . . ISARIC4C investigators. (2020). Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.. BMJ: British Medical Journal, 370. doi:10.1136/bmj.m3339

    DOI: 10.1136/bmj.m3339

    What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? - A harmonised, global longitudinal observational study (Journal article)

    Sigfrid, L., Cevik, M., Jesudason, E., Lim, W. S., Rello, J., Amuasi, J. H., . . . Scott, J. (2020). What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? - A harmonised, global longitudinal observational study. doi:10.1101/2020.08.26.20180950

    DOI: 10.1101/2020.08.26.20180950

    Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study (Journal article)

    Swann, O., Holden, K., Turtle, L., Pollock, L., Fairfield, C., Drake, T., . . . ISARIC Coronavirus Clinical Characterisation Consortium (ISARIC4C) Investigators. (2020). Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study. BMJ, 370. doi:10.1136/bmj.m3249

    DOI: 10.1136/bmj.m3249

    Complete protection for mice conferred by a DNA vaccine based on the Japanese encephalitis virus P3 strain used to prepare the inactivated vaccine in China (Journal article)

    Zheng, X., Yu, X., Wang, Y., Turtle, L., Cui, M., Wang, R., & Yin, C. (2020). Complete protection for mice conferred by a DNA vaccine based on the Japanese encephalitis virus P3 strain used to prepare the inactivated vaccine in China. VIROLOGY JOURNAL, 17(1). doi:10.1186/s12985-020-01400-3

    DOI: 10.1186/s12985-020-01400-3

    Methods of inactivation of SARS-CoV-2 for downstream biological assays. (Journal article)

    Patterson, E. I., Prince, T., Anderson, E. R., Casas-Sanchez, A., Smith, S. L., Cansado-Utrilla, C., . . . Hughes, G. L. (2020). Methods of inactivation of SARS-CoV-2 for downstream biological assays.. The Journal of infectious diseases. doi:10.1093/infdis/jiaa507

    DOI: 10.1093/infdis/jiaa507

    Outcomes of COVID-19 related hospitalisation among people with HIV in the ISARIC WHO Clinical Characterisation Protocol (UK): a prospective observational study (Journal article)

    Geretti, A., Stockdale, A., Kelly, S., Villa, G., Turtle, L., Semple, M., & Sabin, C. (2020). Outcomes of COVID-19 related hospitalisation among people with HIV in the ISARIC WHO Clinical Characterisation Protocol (UK): a prospective observational study. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 23, 13-14. Retrieved from http://gateway.webofknowledge.com/

    Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score (Journal article)

    Knight, S., Ho, A., Pius, R., Buchan, I., Carson, G., Drake, T., . . . Harrison, E. (2020). Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score. doi:10.1101/2020.07.30.20165464

    DOI: 10.1101/2020.07.30.20165464

    SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus (Journal article)

    Andersson, M., Arancibia-Carcamo, C., Auckland, K., Baillie, K., Barnes, E., Beneke, T., . . . Zambon, M. (2020). SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus. doi:10.12688/wellcomeopenres.16002.1

    DOI: 10.12688/wellcomeopenres.16002.1

    Clinical characteristics of children and young people hospitalised with covid-19 in the United Kingdom: prospective multicentre observational cohort study (Journal article)

    Swann, O., Holden, K., Turtle, L., Pollock, L., Fairfield, C., Drake, T., . . . Semple, M. (2020). Clinical characteristics of children and young people hospitalised with covid-19 in the United Kingdom: prospective multicentre observational cohort study. doi:10.1101/2020.07.14.20153320

    DOI: 10.1101/2020.07.14.20153320

    Global outbreak research: harmony not hegemony (Journal article)

    Characterisation, I. S. A. R. I. C. C. (2020). Global outbreak research: harmony not hegemony. LANCET INFECTIOUS DISEASES, 20(7), 770-772. doi:10.1016/S1473-3099(20)30440-0

    DOI: 10.1016/S1473-3099(20)30440-0

    Respiratory failure alone does not suggest central nervous system invasion by SARS-CoV-2 (Journal article)

    Turtle, L. (2020). Respiratory failure alone does not suggest central nervous system invasion by SARS-CoV-2. JOURNAL OF MEDICAL VIROLOGY, 92(7), 705-706. doi:10.1002/jmv.25828

    DOI: 10.1002/jmv.25828

    T cell immunity rather than antibody mediates cross-protection against Zika virus infection conferred by a live attenuated Japanese encephalitis SA14-14-2 vaccine. (Journal article)

    Wang, R., Zhen, Z., Turtle, L., Hou, B., Li, Y., Wu, N., . . . An, J. (2020). T cell immunity rather than antibody mediates cross-protection against Zika virus infection conferred by a live attenuated Japanese encephalitis SA14-14-2 vaccine.. Applied microbiology and biotechnology. doi:10.1007/s00253-020-10710-z

    DOI: 10.1007/s00253-020-10710-z

    Antibody testing for COVID-19: A report from the National COVID Scientific Advisory Panel [version 1; peer review: 2 approved] (Journal article)

    Adams, E. R., Ainsworth, M., Anand, R., Andersson, M. I., Auckland, K., Baillie, J. K., . . . Whitehouse, J. (2020). Antibody testing for COVID-19: A report from the National COVID Scientific Advisory Panel [version 1; peer review: 2 approved]. Wellcome Open Research, 5. doi:10.12688/wellcomeopenres.15927.1

    DOI: 10.12688/wellcomeopenres.15927.1

    Cancer datasets and the SARS-CoV-2 pandemic: establishing principles for collaboration. (Journal article)

    Palmieri, C., Palmer, D., Openshaw, P. J., Baille, J. K., Semple, M. G., & Turtle, L. (2020). Cancer datasets and the SARS-CoV-2 pandemic: establishing principles for collaboration.. ESMO Open, 5(3). doi:10.1136/esmoopen-2020-000825

    DOI: 10.1136/esmoopen-2020-000825

    Methods of inactivation of SARS-CoV-2 for downstream biological assays. (Journal article)

    Patterson, E. I., Prince, T., Anderson, E. R., Casas-Sanchez, A., Smith, S. L., Cansado-Utrilla, C., . . . Hughes, G. L. (2020). Methods of inactivation of SARS-CoV-2 for downstream biological assays.. bioRxiv : the preprint server for biology. doi:10.1101/2020.05.21.108035

    DOI: 10.1101/2020.05.21.108035

    Two Is Better Than One: Evidence for T-Cell Cross-Protection Between Dengue and Zika and Implications on Vaccine Design. (Journal article)

    Subramaniam, K. S., Lant, S., Goodwin, L., Grifoni, A., Weiskopf, D., & Turtle, L. (2020). Two Is Better Than One: Evidence for T-Cell Cross-Protection Between Dengue and Zika and Implications on Vaccine Design.. Frontiers in Immunology, 11, 517. doi:10.3389/fimmu.2020.00517

    DOI: 10.3389/fimmu.2020.00517

    2019

    'More than devastating'-patient experiences and neurological sequelae of Japanese encephalitis (Journal article)

    Turtle, L., Easton, A., Defres, S., Ellul, M., Bovill, B., Hoyle, J., . . . Solomon, T. (2019). 'More than devastating'-patient experiences and neurological sequelae of Japanese encephalitis. JOURNAL OF TRAVEL MEDICINE, 26(7). doi:10.1093/jtm/taz064

    DOI: 10.1093/jtm/taz064

    Low population Japanese encephalitis virus (JEV) seroprevalence in Udayapur district, Nepal, three years after a JE vaccination programme: a case for further catch up campaigns? (Journal article)

    Turtle, L. C. W. (n.d.). Low population Japanese encephalitis virus (JEV) seroprevalence in Udayapur district, Nepal, three years after a JE vaccination programme: a case for further catch up campaigns?. PLoS Neglected Tropical Diseases, 13. doi:10.1371/journal.pntd.0007269

    DOI: 10.1371/journal.pntd.0007269

    Two Types of Shaking (Chapter)

    Turtle and Gemma Buxton, L. (2019). Two Types of Shaking. In Case Studies in Neurological Infections of Adults and Children (pp. 255-259). Cambridge University Press. doi:10.1017/9781139628839.060

    DOI: 10.1017/9781139628839.060

    2018

    Closing The Brief Case: A Rare Case of Invasive Amebiasis Requiring Emergency Subtotal Colectomy in an HIV-Positive Man. (Journal article)

    Wingfield, T., Ball, R., Woolley, S. D., Campbell, F., Heath, R. M., Beeching, N. J., & Turtle, L. (2018). Closing The Brief Case: A Rare Case of Invasive Amebiasis Requiring Emergency Subtotal Colectomy in an HIV-Positive Man.. Journal of clinical microbiology, 56(8). doi:10.1128/jcm.01704-17

    DOI: 10.1128/jcm.01704-17

    The Brief Case: A Rare Case of Invasive Amebiasis Requiring Emergency Subtotal Colectomy in an HIV-Positive Man (Journal article)

    Wingfield, T., Ball, R., Woolley, S. D., Campbell, F., Heath, R. M., Beeching, N. J., & Turtle, L. (2018). The Brief Case: A Rare Case of Invasive Amebiasis Requiring Emergency Subtotal Colectomy in an HIV-Positive Man. JOURNAL OF CLINICAL MICROBIOLOGY, 56(8). doi:10.1128/JCM.01703-17

    DOI: 10.1128/JCM.01703-17

    Japanese encephalitis - the prospects for new treatments (Journal article)

    Turtle, L., & Solomon, T. (2018). Japanese encephalitis - the prospects for new treatments. Nature Reviews Neurology, 14(5), 298-313. doi:10.1038/nrneurol.2018.30

    DOI: 10.1038/nrneurol.2018.30

    Structural study of the C-terminal domain of non-structural protein 1 from Japanese encephalitis virus (Journal article)

    Poonsiri, T., Wright, G. S. A., Diamond, M. S., Turtle, L., Solomon, T., & Antonyuk, S. V. (2018). Structural study of the C-terminal domain of non-structural protein 1 from Japanese encephalitis virus. Journal of Virology, 92(7). doi:10.1128/jvi.01868-17

    DOI: 10.1128/jvi.01868-17

    The spectrum of neurological disease associated with Zika and chikungunya viruses in adults in Rio de Janeiro, Brazil: A case series (Journal article)

    Mehta, R., Soares, C. N., Medialdea-Carrera, R., Ellul, M., Texeira da Silva, M. T., Rosala-Hallas, A., . . . Solomon, T. (2018). The spectrum of neurological disease associated with Zika and chikungunya viruses in adults in Rio de Janeiro, Brazil: A case series. PLoS Neglected Tropical Diseases, 12(2). doi:10.1371/journal.pntd.0006212

    DOI: 10.1371/journal.pntd.0006212

    Risk assessment for Japanese encephalitis vaccination (Journal article)

    Turtle, L., & Driver, C. (2018). Risk assessment for Japanese encephalitis vaccination. HUMAN VACCINES & IMMUNOTHERAPEUTICS, 14(1), 213-217. doi:10.1080/21645515.2017.1380756

    DOI: 10.1080/21645515.2017.1380756

    2017

    Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans (Journal article)

    Grifoni, A., Pham, J., Sidney, J., O'Rourke, P. H., Paul, S., Peters, B., . . . Sette, A. (2017). Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans. JOURNAL OF VIROLOGY, 91(24). doi:10.1128/JVI.01469-17

    DOI: 10.1128/JVI.01469-17

    Global Assessment of Dengue Virus-Specific CD4+ T Cell Responses in Dengue-Endemic Areas (Journal article)

    Grifoni, A., Angelo, M. A., Lopez, B., O'Rourke, P. H., Sidney, J., Cerpas, C., . . . Weiskopf, D. (2017). Global Assessment of Dengue Virus-Specific CD4+ T Cell Responses in Dengue-Endemic Areas. Frontiers in Immunology, 8. doi:10.3389/fimmu.2017.01309

    DOI: 10.3389/fimmu.2017.01309

    Cellular Immune Responses to Live Attenuated Japanese Encephalitis (JE) Vaccine SA14-14-2 in Adults in a JE/dengue Co- Endemic Area (Journal article)

    Turtle, L. C. W., Tatullo, F., Bali, T., Ravi, V., Soni, M., Chan, S., . . . Solomon, T. (2017). Cellular Immune Responses to Live Attenuated Japanese Encephalitis (JE) Vaccine SA14-14-2 in Adults in a JE/dengue Co- Endemic Area. PLoS Neglected Tropical Diseases, 11(01), 23 pages. doi:10.1371/journal.pntd.0005263

    DOI: 10.1371/journal.pntd.0005263

    Haloprogin (Chapter)

    Ramos-Martín, V., & Hope, W. (2017). Haloprogin. In Kucers the Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs, Seventh Edition (pp. 2933-2935). doi:10.1201/9781315152110

    DOI: 10.1201/9781315152110

    2016

    Human T cell responses to Japanese encephalitis virus in health and disease (Journal article)

    Turtle, L., Bali, T., Buxton, G., Chib, S., Chan, S., Soni, M., . . . Solomon, T. (2016). Human T cell responses to Japanese encephalitis virus in health and disease. Journal of Experimental Medicine, 213(7), 1331-1352. doi:10.1084/jem.20151517

    DOI: 10.1084/jem.20151517

    2015

    An integrated model of care for neurological infections: the first six years of referrals to a specialist service at a university teaching hospital in Northwest England (Journal article)

    Turtle, L., Jung, A., Beeching, N. J., Cocker, D., Davies, G. R., Nicolson, A., . . . Solomon, T. (2015). An integrated model of care for neurological infections: the first six years of referrals to a specialist service at a university teaching hospital in Northwest England. BMC INFECTIOUS DISEASES, 15. doi:10.1186/s12879-015-1109-3

    DOI: 10.1186/s12879-015-1109-3

    A Preliminary Randomized Double Blind Placebo-Controlled Trial of Intravenous Immunoglobulin for Japanese Encephalitis in Nepal (vol 10, e0122608, 2015) (Journal article)

    Rayamajhi, A., Nightingale, S., Bhatta, N. K., Singh, R., Ledger, E., Bista, K. P., . . . Solomon, T. (2015). A Preliminary Randomized Double Blind Placebo-Controlled Trial of Intravenous Immunoglobulin for Japanese Encephalitis in Nepal (vol 10, e0122608, 2015). PLOS ONE, 10(8). doi:10.1371/journal.pone.0136008

    DOI: 10.1371/journal.pone.0136008

    A Preliminary Randomized Double Blind Placebo-Controlled Trial of Intravenous Immunoglobulin for Japanese Encephalitis in Nepal (Journal article)

    Rayamajhi, A., Nightingale, S., Bhatta, N. K., Singh, R., Ledger, E., Bista, K. P., . . . Solomon, T. (2015). A Preliminary Randomized Double Blind Placebo-Controlled Trial of Intravenous Immunoglobulin for Japanese Encephalitis in Nepal. PLOS ONE, 10(4). doi:10.1371/journal.pone.0122608

    DOI: 10.1371/journal.pone.0122608

    A Survey of UK Healthcare Workers’ Attitudes on Volunteering to Help with the Ebola Outbreak in West Africa (Journal article)

    Turtle, L., McGill, F., Bettridge, J., Matata, C., Christley, R., & Solomon, T. (2015). A Survey of UK Healthcare Workers’ Attitudes on Volunteering to Help with the Ebola Outbreak in West Africa. PLoS ONE, 10(3). doi:10.1371/journal.pone.0120013

    DOI: 10.1371/journal.pone.0120013

    2014

    A case of iatrogenic adrenal suppression after co-administration of cobicistat and fluticasone nasal drops (Journal article)

    Lewis, J., Turtle, L., Khoo, S., & Nsutebu, E. (2014). A case of iatrogenic adrenal suppression after co-administration of cobicistat and fluticasone nasal drops. AIDS, 28(17), 2636-2637. doi:10.1097/QAD.0000000000000462

    DOI: 10.1097/QAD.0000000000000462

    EBOLA CRISIS What stops healthcare workers volunteering to fight Ebola in west Africa? (Journal article)

    Solomon, T., Turtle, L., McGill, F., Matata, C., & Christley, R. (2014). EBOLA CRISIS What stops healthcare workers volunteering to fight Ebola in west Africa?. BMJ-BRITISH MEDICAL JOURNAL, 349. doi:10.1136/bmj.g6443

    DOI: 10.1136/bmj.g6443

    Encephalitis, Viral (Chapter)

    Turtle, L., & Solomon, T. (2014). Encephalitis, Viral. In Encyclopedia of the Neurological Sciences (pp. 20-24). Elsevier. doi:10.1016/b978-0-12-385157-4.00375-4

    DOI: 10.1016/b978-0-12-385157-4.00375-4

    Japanese encephalitis virus infection. (Chapter)

    Griffiths, M. J., Turtle, L., & Solomon, T. (2014). Japanese encephalitis virus infection.. In Unknown Book (Vol. 123, pp. 561-576). doi:10.1016/b978-0-444-53488-0.00026-2

    DOI: 10.1016/b978-0-444-53488-0.00026-2

    2013

    Innate Immune Mechanisms in Japanese Encephalitis Virus Infection: Effect on Transcription of Pattern Recognition Receptors in Mouse Neuronal Cells and Brain Tissue (Journal article)

    Fadnis, P. R., Ravi, V., Desai, A., Turtle, L., & Solomon, T. (2013). Innate Immune Mechanisms in Japanese Encephalitis Virus Infection: Effect on Transcription of Pattern Recognition Receptors in Mouse Neuronal Cells and Brain Tissue. VIRAL IMMUNOLOGY, 26(6), 366-377. doi:10.1089/vim.2013.0016

    DOI: 10.1089/vim.2013.0016

    Japanese Encephalitis Virus Infection (Chapter)

    Turtle, L., & Solomon, T. (2013). Japanese Encephalitis Virus Infection. In Viral Infections of the Human Nervous System (pp. 271-293). Springer Basel. doi:10.1007/978-3-0348-0425-7_11

    DOI: 10.1007/978-3-0348-0425-7_11

    2012

    In routine UK hospital practice T-SPOT.TB (TM) is useful in some patients with a modest pre-test probability of active tuberculosis (Journal article)

    Turtle, L., Kemp, T., Davies, G. R., Squire, S. B., Beeching, N. J., & Beadsworth, M. B. J. (2012). In routine UK hospital practice T-SPOT.TB (TM) is useful in some patients with a modest pre-test probability of active tuberculosis. EUROPEAN JOURNAL OF INTERNAL MEDICINE, 23(4), 363-367. doi:10.1016/j.ejim.2012.01.002

    DOI: 10.1016/j.ejim.2012.01.002

    In routine UK hospital practice T-SPOT.TB™ is useful in some patients with a modest pre-test probability of active tuberculosis. (Journal article)

    Turtle, L., Kemp, T., Davies, G. R., Squire, S. B., Beeching, N. J., & Beadsworth, M. B. J. (2012). In routine UK hospital practice T-SPOT.TB™ is useful in some patients with a modest pre-test probability of active tuberculosis.. European journal of internal medicine, 23(4), 363-367. doi:10.1016/j.ejim.2012.01.002

    DOI: 10.1016/j.ejim.2012.01.002

    Encephalitis caused by flaviviruses (Journal article)

    Turtle, L., Griffiths, M. J., & Solomon, T. (2012). Encephalitis caused by flaviviruses. QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 105(3), 219-223. doi:10.1093/qjmed/hcs013

    DOI: 10.1093/qjmed/hcs013

    Encephalitis caused by flaviviruses. (Journal article)

    Turtle, L., Griffiths, M. J., & Solomon, T. (2012). Encephalitis caused by flaviviruses.. QJM., 105(3), 219-223. doi:10.1093/qjmed/hcs013

    DOI: 10.1093/qjmed/hcs013

    2011

    Intensive Care Usage by HIV-Positive Patients in the HAART Era. (Journal article)

    Turtle, L., Vyakernam, R., Menon-Johansson, A., Nelson, M. R., & Soni, N. (2011). Intensive Care Usage by HIV-Positive Patients in the HAART Era.. Interdisciplinary perspectives on infectious diseases, 2011, 847835. doi:10.1155/2011/847835

    DOI: 10.1155/2011/847835

    'Septrin psychosis' among renal transplant patients with Pneumocystis jirovecii pneumonia (Journal article)

    Walker, L. E., Thomas, S., McBride, C., Howse, M., Turtle, L. C. W., Vivancos, R., . . . Beadsworth, M. B. J. (2011). 'Septrin psychosis' among renal transplant patients with Pneumocystis jirovecii pneumonia. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 66(5), 1117-1119. doi:10.1093/jac/dkr050

    DOI: 10.1093/jac/dkr050

    'Septrin psychosis' among renal transplant patients with Pneumocystis jirovecii pneumonia. (Journal article)

    Walker, L. E., Thomas, S., McBride, C., Howse, M., Turtle, L. C. W., Vivancos, R., . . . Beadsworth, M. B. J. (2011). 'Septrin psychosis' among renal transplant patients with Pneumocystis jirovecii pneumonia.. The Journal of antimicrobial chemotherapy, 66(5), 1117-1119. doi:10.1093/jac/dkr050

    DOI: 10.1093/jac/dkr050

    2009

    An evaluation of the usefulness of neuroimaging for the diagnosis of Japanese encephalitis (Journal article)

    Dung, N. M., Turtle, L., Chong, W. K., Mai, N. T., Thao, T. T., Thuy, T. T., . . . Solomon, T. (2009). An evaluation of the usefulness of neuroimaging for the diagnosis of Japanese encephalitis. JOURNAL OF NEUROLOGY, 256(12), 2052-2060. doi:10.1007/s00415-009-5249-5

    DOI: 10.1007/s00415-009-5249-5

    Severe pneumonia caused by ciprofloxacin resistant panton-valentine leukocidin producing community acquired meticillin resistant Staphylococcus aureus (Journal article)

    Turtle, L., Wey, E., & James, E. (2009). Severe pneumonia caused by ciprofloxacin resistant panton-valentine leukocidin producing community acquired meticillin resistant Staphylococcus aureus. JOURNAL OF INFECTION, 58(1), 86-87. doi:10.1016/j.jinf.2008.10.008

    DOI: 10.1016/j.jinf.2008.10.008

    2008

    Tics, Twitches, Tales: The Experiences of Gilles de la Tourette's Syndrome (Journal article)

    Turtle, L., & Robertson, M. M. (2008). Tics, Twitches, Tales: The Experiences of Gilles de la Tourette's Syndrome. AMERICAN JOURNAL OF ORTHOPSYCHIATRY, 78(4), 449-455. doi:10.1037/a0014329

    DOI: 10.1037/a0014329

    2007

    Medical emergencies in human immunodeficiency virus infected patients (Journal article)

    Turtle, L. (2007). Medical emergencies in human immunodeficiency virus infected patients. Current Anaesthesia & Critical Care, 18(2), 94-106. doi:10.1016/j.cacc.2007.03.004

    DOI: 10.1016/j.cacc.2007.03.004

    2003

    Urocortin protects cardiac myocytes from ischemia/reperfusion injury by attenuating calcium insensitive phospholipase A(2) gene expression (Journal article)

    Lawrence, K. M., Scarabelli, T. M., Turtle, L., Chanalaris, A., Townsend, P. A., Carroll, C. J., . . . Latchman, D. S. (2003). Urocortin protects cardiac myocytes from ischemia/reperfusion injury by attenuating calcium insensitive phospholipase A(2) gene expression. FASEB JOURNAL, 17(13), 2313-+. doi:10.1096/fj.02-0832fje

    DOI: 10.1096/fj.02-0832fje