2022
Needham, E. J., Ren, A. L., Digby, R. J., Norton, E. J., Ebrahimi, S., Outtrim, J. G., . . . Cambridge NeuroCOVID Group the CITIID-NIHR COVID-19 BioResource Collaboration and Cambridge NIHR Clinical Research Facility. (2022). Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses.. Brain : a journal of neurology, awac321. doi:10.1093/brain/awac321DOI: 10.1093/brain/awac321
Wood, G. K., Babar, R., Ellul, M. A., Thomas, R. H., Van Den Tooren, H., Easton, A., . . . Michael, B. D. (2022). Acute seizure risk in patients with encephalitis: development and validation of clinical prediction models from two independent prospective multicentre cohorts. BMJ Neurology Open, 4(2), e000323. doi:10.1136/bmjno-2022-000323DOI: 10.1136/bmjno-2022-000323
Judge, S. J., Bloomstein, J. D., Sholevar, C. J., Darrow, M. A., Stoffel, K. M., Vick, L. V., . . . Canter, R. J. (2022). Transcriptome Analysis of Tumor-Infiltrating Lymphocytes Identifies NK Cell Gene Signatures Associated With Lymphocyte Infiltration and Survival in Soft Tissue Sarcomas.. Frontiers in immunology, 13, 893177. doi:10.3389/fimmu.2022.893177DOI: 10.3389/fimmu.2022.893177
Rebhun, R. B., York, D., Cruz, S. M., Judge, S. J., Razmara, A. M., Farley, L. E., . . . Canter, R. J. (2022). Inhaled recombinant human IL-15 in dogs with naturally occurring pulmonary metastases from osteosarcoma or melanoma: a phase 1 study of clinical activity and correlates of response.. Journal for immunotherapy of cancer, 10(6), e004493. doi:10.1136/jitc-2022-004493DOI: 10.1136/jitc-2022-004493
Dunai, C., Collie, C., & Michael, B. D. (2022). Immune-Mediated Mechanisms of COVID-19 Neuropathology. FRONTIERS IN NEUROLOGY, 13. doi:10.3389/fneur.2022.882905DOI: 10.3389/fneur.2022.882905
Killers on the loose: Immunotherapeutic strategies to improve NK cell-based therapy for cancer treatment. (Chapter)
Dunai, C., Ames, E., Ochoa, M. C., Fernandez-Sendin, M., Melero, I., Simonetta, F., . . . Alvarez, M. (2022). Killers on the loose: Immunotherapeutic strategies to improve NK cell-based therapy for cancer treatment.. In Unknown Book (Vol. 370, pp. 65-122). doi:10.1016/bs.ircmb.2022.04.001DOI: 10.1016/bs.ircmb.2022.04.001
2021
Increased efficacy of dual proinflammatory cytokine blockade on acute GVHD while maintaining GVT effects (Journal article)
Khuat, L. T., V. Vick, L., Dunai, C., Collins, C. P., More, S. K., Le, C. T., . . . Murphy, W. J. (2021). Increased efficacy of dual proinflammatory cytokine blockade on acute GVHD while maintaining GVT effects. BLOOD, 138(24), 2583-2588. doi:10.1182/blood.2021011216DOI: 10.1182/blood.2021011216
Aguilar, E. G., Dunai, C., Judge, S. J., Zamora, A. E., Khuat, L. T., Vick, L. V., . . . Murphy, W. J. (2021). Activation status dictates the function of unlicensed natural killer cells in mice and humans. BLOOD ADVANCES, 5(20), 4219-4232. doi:10.1182/bloodadvances.2021004589DOI: 10.1182/bloodadvances.2021004589
Khuat, L. T., Vick, L. V., Choi, E., Dunai, C., Merleev, A. A., Maverakis, E., . . . Murphy, W. J. (2021). Mechanisms by Which Obesity Promotes Acute Graft-<i>Versus</i>-Host Disease in Mice.. Frontiers in immunology, 12, 752484. doi:10.3389/fimmu.2021.752484DOI: 10.3389/fimmu.2021.752484
Ray, S. T. J., Abdel-Mannan, O., Sa, M., Fuller, C., Wood, G. K., Pysden, K., . . . grp, C. S. (2021). Neurological manifestations of SARS-CoV-2 infection in hospitalised children and adolescents in the UK: a prospective national cohort study. LANCET CHILD & ADOLESCENT HEALTH, 5(9), 631-641. doi:10.1016/S2352-4642(21)00193-0DOI: 10.1016/S2352-4642(21)00193-0
Hosoya, T., Cordelia, D., Michael, B. D., Miyabe, C., Nagai, J., Murooka, T. T., & Miyabe, Y. (2021). Editorial: Targeting the Chemoattractant System in Inflammation. FRONTIERS IN PHARMACOLOGY, 12. doi:10.3389/fphar.2021.744290DOI: 10.3389/fphar.2021.744290
Skin-Resident beta 2AR Signaling Delays Burn Wound Healing (Journal article)
Nguyen, A. V., Caryotakis, S. E., Wang, M., Gallegos, A., Bagood, M. D., Dunai, C., . . . Soulika, A. M. (2021). Skin-Resident beta 2AR Signaling Delays Burn Wound Healing. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 141(8), 2098-+. doi:10.1016/j.jid.2021.02.010DOI: 10.1016/j.jid.2021.02.010
Mouse Preclinical Cancer Immunotherapy Modeling Involving Anti-PD-1 Therapies Reveals the Need to Use Mouse Reagents to Mirror Clinical Paradigms (Journal article)
Monjazeb, A. M., Wang, Z., Vick, L. V., Dunai, C., Minnar, C., Khuat, L. T., & Murphy, W. J. (n.d.). Mouse Preclinical Cancer Immunotherapy Modeling Involving Anti-PD-1 Therapies Reveals the Need to Use Mouse Reagents to Mirror Clinical Paradigms. Cancers, 13(4), 729. doi:10.3390/cancers13040729DOI: 10.3390/cancers13040729
2020
Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation (Journal article)
Khuat, L. T., Le, C. T., Pai, C. -C. S., Shields-Cutler, R. R., Holtan, S. G., Rashidi, A., . . . Murphy, W. J. (2020). Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation. SCIENCE TRANSLATIONAL MEDICINE, 12(571). doi:10.1126/scitranslmed.aay7713DOI: 10.1126/scitranslmed.aay7713
Judge, S. J., Darrow, M. A., Thorpe, S. W., Gingrich, A. A., O'Donnell, E. F., Bellini, A. R., . . . Canter, R. J. (2020). Analysis of tumor-infiltrating NK and T cells highlights IL-15 stimulation and TIGIT blockade as a combination immunotherapy strategy for soft tissue sarcomas. . Journal for immunotherapy of cancer, 8(2), e001355. doi:10.1136/jitc-2020-001355DOI: 10.1136/jitc-2020-001355
Alvarez, M., Dunai, C., Khuat, L. T., Aguilar, E. G., Barao, I., & Murphy, W. J. (2020). IL-2 and Anti-TGF-β Promote NK Cell Reconstitution and Anti-tumor Effects after Syngeneic Hematopoietic Stem Cell Transplantation. . Cancers, 12(11), E3189. doi:10.3390/cancers12113189DOI: 10.3390/cancers12113189
PD-1 Blockade Reverses Obesity-Mediated T Cell Priming Impairment (Journal article)
Le, C. T., Khuat, L. T., Caryotakis, S. E., Wang, M., Dunai, C., Nguyen, A. V., . . . Soulika, A. M. (2020). PD-1 Blockade Reverses Obesity-Mediated T Cell Priming Impairment. FRONTIERS IN IMMUNOLOGY, 11. doi:10.3389/fimmu.2020.590568DOI: 10.3389/fimmu.2020.590568
Minimal PD-1 expression in mouse and human NK cells under diverse conditions (Journal article)
Judge, S. J., Dunai, C., Aguilar, E. G., Vick, S. C., Sturgill, I. R., Khuat, L. T., . . . Murphy, W. J. (2020). Minimal PD-1 expression in mouse and human NK cells under diverse conditions. JOURNAL OF CLINICAL INVESTIGATION, 130(6), 3051-3068. doi:10.1172/JCI33353DOI: 10.1172/JCI33353
2019
Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade (Journal article)
Wang, Z., Aguilar, E. G., Luna, J. I., Dunai, C., Khuat, L. T., Le, C. T., . . . Monjazeb, A. M. (2019). Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade. NATURE MEDICINE, 25(1), 141-+. doi:10.1038/s41591-018-0221-5DOI: 10.1038/s41591-018-0221-5
2018
NK cells for PD-1/PD-L1 blockade immunotherapy: pinning down the NK cell (Journal article)
Dunai, C., & Murphy, W. J. (2018). NK cells for PD-1/PD-L1 blockade immunotherapy: pinning down the NK cell. JOURNAL OF CLINICAL INVESTIGATION, 128(10), 4251-4253. doi:10.1172/JCI123121DOI: 10.1172/JCI123121
2017
Licensing delineates helper and effector NK cell subsets during viral infection (Journal article)
Zamora, A. E., Aguilar, E. G., Sungur, C. M., Khuat, L. T., Dunai, C., Lochhead, G. R., . . . Murphy, W. J. (2017). Licensing delineates helper and effector NK cell subsets during viral infection. JCI INSIGHT, 2(10). doi:10.1172/jci.insight.87032DOI: 10.1172/jci.insight.87032
