2024
de Carvalho, R. L., Wood, J. M., Almeida, R. G., Berry, N. G., da Silva Júnior, E. N., & Bower, J. F. (n.d.). The Synthesis and Reactivity of Naphthoquinonynes. Angewandte Chemie. doi:10.1002/ange.202400188DOI: 10.1002/ange.202400188
de Carvalho, R. L., Wood, J. M., Almeida, R. G., Berry, N. G., da Silva Júnior, E. N., & Bower, J. F. (2024). The Synthesis and Reactivity of Naphthoquinonynes.. Angewandte Chemie (International ed. in English), e202400188. doi:10.1002/anie.202400188DOI: 10.1002/anie.202400188
Clare, R. H., Dawson, C. A., Westhorpe, A., Albulescu, L. -O., Woodley, C. M., Mosallam, N., . . . Casewell, N. R. (2024). Snakebite drug discovery: high-throughput screening to identify novel snake venom metalloproteinase toxin inhibitors. Frontiers in Pharmacology, 14. doi:10.3389/fphar.2023.1328950DOI: 10.3389/fphar.2023.1328950
Lisauskaitė, M., Nixon, G. L., Woodley, C. M., Berry, N. G., Coninckx, A., Qie, L. C., . . . O'Neill, P. M. (2024). Design, synthesis and modelling of photoreactive chemical probes for investigating target engagement of plasmepsin IX and X in <i>Plasmodium falciparum</i>.. RSC chemical biology, 5(1), 19-29. doi:10.1039/d3cb00109aDOI: 10.1039/d3cb00109a
2023
Impact of fluoroquinolones and aminoglycosides on P. aeruginosa virulence factor production and cytotoxicity (vol 479, pg 2511, 2022) (Journal article)
Foulkes, D. M., McLean, K., Sloniecka, M., Rustidge, S., Byrne, D. P., Haneef, A. S., . . . Kaye, S. B. (2023). Impact of fluoroquinolones and aminoglycosides on P. aeruginosa virulence factor production and cytotoxicity (vol 479, pg 2511, 2022). BIOCHEMICAL JOURNAL, 480(7), 491-493. doi:10.1042/BCJ20220527_CORDOI: 10.1042/BCJ20220527_COR
Albulescu, L. -O., Westhorpe, A., Clare, R. H., Woodley, C. M., James, N., Kool, J., . . . Casewell, N. R. (2023). Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform.. Frontiers in pharmacology, 14, 1331224. doi:10.3389/fphar.2023.1331224DOI: 10.3389/fphar.2023.1331224
Jeffreys, L. N., Ardrey, A., Hafiz, T. A., Dyer, L. -A., Warman, A. J., Mosallam, N., . . . Biagini, G. A. (2023). Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis. ACS INFECTIOUS DISEASES. doi:10.1021/acsinfecdis.2c00283DOI: 10.1021/acsinfecdis.2c00283
2022
Foulkes, D. M., McLean, K., Sloniecka, M., Rustidge, S., Byrne, D. P., Haneef, A. S., . . . Kaye, S. B. (2022). Impact of fluoroquinolones and aminoglycosides on<i> P.</i><i> aeruginosa</i> virulence factor production and. BIOCHEMICAL JOURNAL, 479(24), 2511-2527. doi:10.1042/BCJ20220527DOI: 10.1042/BCJ20220527
Amporndanai, K., Pinthong, N., O'Neill, P. M., Hong, W. D., Amewu, R. K., Pidathala, C., . . . Antonyuk, S. V. (2022). Targeting the Ubiquinol-Reduction (Q<sub>i</sub>) Site of the Mitochondrial Cytochrome <i>bc<sub>1</sub></i> Complex for the Development of Next Generation Quinolone Antimalarials. BIOLOGY-BASEL, 11(8). doi:10.3390/biology11081109DOI: 10.3390/biology11081109
Norman, B. P., Davison, A. S., Hughes, J. H., Sutherland, H., Wilson, P. J. M., Berry, N. G., . . . Gallagher, J. A. (2022). Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism. GENES & DISEASES, 9(4), 1129-1142. doi:10.1016/j.gendis.2021.02.007DOI: 10.1016/j.gendis.2021.02.007
P-18 Impact of fluoroquinolones and aminoglycosides on P<i>. aeruginosa</i> virulence factor production and cytotoxicity. (Conference Paper)
Kaye, S., McLean, K., Foulkes, D. M., Sloniecka, M., Byrne, D., Haneef, A. S., . . . Fernig, D. G. (2022). P-18 Impact of fluoroquinolones and aminoglycosides on P<i>. aeruginosa</i> virulence factor production and cytotoxicity.. In BMJ open ophthalmology Vol. 7 (pp. A6). doi:10.1136/bmjophth-2022-bcm.15DOI: 10.1136/bmjophth-2022-bcm.15
Petuya, R., Durdy, S., Antypov, D., Gaultois, M. W., Berry, N. G., Darling, G. R., . . . Rosseinsky, M. J. (2022). Machine-Learning Prediction of Metal-Organic Framework Guest Accessibility from Linker and Metal Chemistry. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 61(9). doi:10.1002/anie.202114573DOI: 10.1002/anie.202114573
Pétuya, R., Durdy, S., Antypov, D., Gaultois, M. W., Berry, N. G., Darling, G. R., . . . Rosseinsky, M. J. (2022). Machine‐Learning Prediction of Metal–Organic Framework Guest Accessibility from Linker and Metal Chemistry. Angewandte Chemie, 134(9). doi:10.1002/ange.202114573DOI: 10.1002/ange.202114573
2021
Chu, C. S. M., Simpson, J. D., O'Neill, P. M., & Berry, N. G. (2021). Machine learning-Predicting Ames mutagenicity of small molecules. JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 109. doi:10.1016/j.jmgm.2021.108011DOI: 10.1016/j.jmgm.2021.108011
Impact of fluoroquinolones and aminoglycosides on <i>P. aeruginosa</i> virulence factor production and cytotoxicity (Preprint)
DOI: 10.1101/2021.10.11.463927
McGillan, P., Berry, N. G., Nixon, G. L., Leung, S. C., Webborn, P. J. H., Wenlock, M. C., . . . O’Neill, P. M. (2021). Development of Pyrazolopyrimidine Anti-Wolbachia Agents for the Treatment of Filariasis. ACS Medicinal Chemistry Letters, 12(9), 1421-1426. doi:10.1021/acsmedchemlett.1c00216DOI: 10.1021/acsmedchemlett.1c00216
Foulkes, D. M., McLean, K., Zheng, Y., Sarsby, J., Haneef, A. S., Fernig, D. G., . . . Kaye, S. B. (2021). A pipeline to evaluate inhibitors of the <i>Pseudomonas</i> <i>aeruginosa</i> exotoxin U. BIOCHEMICAL JOURNAL, 478(3), 647-668. doi:10.1042/BCJ20200780DOI: 10.1042/BCJ20200780
2020
Vriza, A., Canaj, A. B., Vismara, R., Kershaw Cook, L. J., Manning, T. D., Gaultois, M. W., . . . Rosseinsky, M. J. (n.d.). One class classification as a practical approach for accelerating π–π co-crystal discovery. Chemical Science. doi:10.1039/d0sc04263cDOI: 10.1039/d0sc04263c
Waddington, J. C., Meng, X., Illing, P. T., Tailor, A., Adair, K., Whitaker, P., . . . Park, B. K. (2020). Identification of Flucloxacillin-Haptenated HLA-B*57:01 Ligands: Evidence of Antigen Processing and Presentation. TOXICOLOGICAL SCIENCES, 177(2), 454-465. doi:10.1093/toxsci/kfaa124DOI: 10.1093/toxsci/kfaa124
Meng, X., Waddington, J. C., Tailor, A., Lister, A., Hamlett, J., Berry, N., . . . Sporn, M. B. (2020). CDDO-imidazolide Targets Multiple Amino Acid Residues on the Nrf2 Adaptor, Keap1. JOURNAL OF MEDICINAL CHEMISTRY, 63(17), 9965-9976. doi:10.1021/acs.jmedchem.0c01088DOI: 10.1021/acs.jmedchem.0c01088
Yan, Y., Carrington, E. J., Petuya, R., Whitehead, G. F. S., Verma, A., Hylton, R. K., . . . Rosseinsky, M. J. (2020). Amino Acid Residues Determine the Response of Flexible Metal-Organic Frameworks to Guests. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 142(35), 14903-14913. doi:10.1021/jacs.0c03853DOI: 10.1021/jacs.0c03853
Thomson, P. J., Illing, P. T., Farrell, J., Alhaidari, M., Bell, C. C., Berry, N., . . . Naisbitt, D. J. (2020). Modification of the cyclopropyl moiety of abacavir provides insight into the structure activity relationship between HLA‐B*57:01 binding and T‐cell activation. ALLERGY, 75(3), 636-647. doi:10.1111/all.14057DOI: 10.1111/all.14057
2019
Foulkes, D. M., McLean, K., Haneef, A. S., Fernig, D. G., Winstanley, C., Berry, N., & Kaye, S. B. (2019). <i>Pseudomonas aeruginosa</i> Toxin ExoU as a Therapeutic Target in the Treatment of Bacterial Infections. MICROORGANISMS, 7(12). doi:10.3390/microorganisms7120707DOI: 10.3390/microorganisms7120707
Structure-Based Design of Nucleoside-Derived Analogues as Sulfotransferase Inhibitors (Journal article)
Kershaw, N., Byrne, D., Parsons, H., Berry, N. G., Fernig, D., Eyers, P. A., & Cosstick, R. (2019). Structure-Based Design of Nucleoside-Derived Analogues as Sulfotransferase Inhibitors. doi:10.26434/chemrxiv.9944243DOI: 10.26434/chemrxiv.9944243
Kershaw, N., Byrne, D., Parsons, H., Berry, N., Fernig, D., Eyers, P., & Cosstick, R. (2019). Structure-Based Design of Nucleoside-Derived Analogues as Sulfotransferase Inhibitors. RSC Advances: an international journal to further the chemical sciences. doi:10.1039/C9RA07567DDOI: 10.1039/C9RA07567D
Kershaw, N. M., Byrne, D. P., Parsons, H., Berry, N. G., Fernig, D. G., Eyers, P. A., & Cosstick, R. (2019). Structure-based design of nucleoside-derived analogues as sulfotransferase inhibitors. RSC ADVANCES, 9(55), 32165-32173. doi:10.1039/c9ra07567dDOI: 10.1039/c9ra07567d
Carrington, E. J., Petuya, R., Hylton, R. K., Yan, Y., Antypov, D., Darling, G. R., . . . Rosseinsky, M. J. (2019). The Anisotropic Responses of a Flexible Metal-Organic Framework Constructed from Asymmetric Flexible Linkers and Heptanuclear Zinc Carboxylate Secondary Building Units. CRYSTAL GROWTH & DESIGN, 19(10), 5604-5618. doi:10.1021/acs.cgd.9b00558DOI: 10.1021/acs.cgd.9b00558
AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis (Journal article)
Hong, W. D., Benayoud, F., Nixon, G. L., Ford, L., Johnston, K. L., Clare, R. H., . . . O'Neill, P. M. (2019). AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(4), 1414-1419. doi:10.1073/pnas.1816585116DOI: 10.1073/pnas.1816585116
Katsoulidis, A., Antypov, D., Whitehead, G., Carrington, E., Adams, D., Berry, N., . . . Rosseinsky, M. (2019). Chemical control of structure and guest uptake by a conformationally mobile porous material. Nature, 565(7738), 213. doi:10.1038/s41586-018-0820-9DOI: 10.1038/s41586-018-0820-9
Clare, R. H., Bardelle, C., Harper, P., Hong, W. D., Borjesson, U., Johnston, K. L., . . . Ward, S. A. (2019). Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides. NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-018-07826-2DOI: 10.1038/s41467-018-07826-2
A NEW RAPID ACTING ANTI-WOLBACHIA DRUG FOR ONCHOCERCIASIS AND LYMPHATIC FILARIASIS (Conference Paper)
Hong, W. D., Johnston, K. L., Berry, N. G., Gusovsky, F., Heming-Way, J., Turner, J. D., . . . O'Neill, P. M. (2019). A NEW RAPID ACTING ANTI-WOLBACHIA DRUG FOR ONCHOCERCIASIS AND LYMPHATIC FILARIASIS. In TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE Vol. 113 (pp. S4). Retrieved from https://www.webofscience.com/
2018
David Hong, W., Leung, S. C., Amporndanai, K., Davies, J., Priestley, R. S., Nixon, G. L., . . . O'Neill, P. M. (2018). Potent Antimalarial 2-Pyrazolyl Quinolone bc1 (Qi) Inhibitors with Improved Drug-like Properties. ACS Medicinal Chemistry Letters, 9(12), 1205-1210. doi:10.1021/acsmedchemlett.8b00371DOI: 10.1021/acsmedchemlett.8b00371
Wong, S. Q., Pontifex, M. G., Phelan, M. M., Pidathala, C., Kraemer, B. C., Barclay, J. W., . . . Morgan, A. (2018). α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy. Neurobiology of disease, 118, 40-54. doi:10.1016/j.nbd.2018.06.013DOI: 10.1016/j.nbd.2018.06.013
N,O- vs N,C-Chelation in Half-Sandwich Iridium Complexes: A Dramatic Effect on Enantioselectivity in Asymmetric Transfer Hydrogenation of Ketones (Journal article)
Zhou, G., Aboo, A. H., Robertson, C. M., Liu, R., Li, Z., Luzyanin, K., . . . Xiao, J. (2018). N,O- vs N,C-Chelation in Half-Sandwich Iridium Complexes: A Dramatic Effect on Enantioselectivity in Asymmetric Transfer Hydrogenation of Ketones. ACS CATALYSIS, 8(9), 8020-8026. doi:10.1021/acscatal.8b02068DOI: 10.1021/acscatal.8b02068
Lawrenson, A. S., Cooper, D. L., O'Neill, P. M., & Berry, N. G. (2018). Study of the antimalarial activity of 4-aminoquinoline compounds against chloroquine-sensitive and chloroquine-resistant parasite strains. JOURNAL OF MOLECULAR MODELING, 24(9). doi:10.1007/s00894-018-3755-zDOI: 10.1007/s00894-018-3755-z
Smith, J. A., Wu, X., Berry, N. G., & Hasell, T. (2018). High Sulfur Content Polymers: The Effect of Crosslinker Structure on Inverse Vulcanization. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 56(16), 1777-1781. doi:10.1002/pola.29067DOI: 10.1002/pola.29067
Byrne, D. P., Li, Y., Ramakrishnan, K., Barsukov, I. L., Yates, E. A., Eyers, C. E., . . . Eyers, P. A. (2018). New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors. BIOCHEMICAL JOURNAL, 475(15), 2417-2433. doi:10.1042/BCJ20180265DOI: 10.1042/BCJ20180265
Byrne, D. P., Li, Y., Ngamlert, P., Ramakrishnan, K., Eyers, C. E., Wells, C., . . . Eyers, P. A. (2018). New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors. BIOCHEMICAL JOURNAL, 475(15), 2435-2455. doi:10.1042/BCJ20180266DOI: 10.1042/BCJ20180266
(Invited) Oxygen Reactions at Poly and Single Crystalline Electrodes in a Sodium-Ion Containing Aprotic Solvent (Journal article)
Hardwick, L. J., Nichols, R., Attard, G., Galloway, T., Berry, N., Padmanabhan, V., . . . Dong, J. -C. (2018). (Invited) Oxygen Reactions at Poly and Single Crystalline Electrodes in a Sodium-Ion Containing Aprotic Solvent. ECS Meeting Abstracts, MA2018-01(37), 2182. doi:10.1149/ma2018-01/37/2182DOI: 10.1149/ma2018-01/37/2182
Nixon, G. L., McEntee, L., Johnson, A., Farrington, N., Whalley, S., Livermore, J., . . . Hope, W. (2018). Repurposing and Reformulation of the Antiparasitic Agent Flubendazole for Treatment of Cryptococcal Meningoencephalitis, a Neglected Fungal Disease. Antimicrobial Agents and Chemotherapy, 62(4), e01909-e01917. doi:10.1128/aac.01909-17DOI: 10.1128/aac.01909-17
Stachulski, A. V., Santoro, M. G., Piacentini, S., Belardo, G., La Frazia, S., Pidathala, C., . . . Rossignol, J. -F. (2018). Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus. FUTURE MEDICINAL CHEMISTRY, 10(8), 851-862. doi:10.4155/fmc-2017-0217DOI: 10.4155/fmc-2017-0217
2017
Almeida, T. B., Carnell, A. J., Barsukov, I. L., & Berry, N. G. (2017). Targeting SxIP-EB1 interaction: An integrated approach to the discovery of small molecule modulators of dynamic binding sites. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-15502-6DOI: 10.1038/s41598-017-15502-6
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL 7-AMINO PYRAZOLOPYRIMIDINE COMPOUNDS POSSESSING POTENT ANTI-WOLBACHIA ACTIVITY FOR THE TREATMENT OF ONCHOCERCIASIS AND LYMPHATIC FILARIASIS (Conference Paper)
McGillan, P., Berry, N. G., Hong, D. W., Cassidy, A., Clare, R., Cook, D., . . . Taylor, M. (2017). DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL 7-AMINO PYRAZOLOPYRIMIDINE COMPOUNDS POSSESSING POTENT ANTI-<i>WOLBACHIA</i> ACTIVITY FOR THE TREATMENT OF ONCHOCERCIASIS AND LYMPHATIC FILARIASIS. In AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Vol. 95 (pp. 348). Retrieved from https://www.webofscience.com/
INDUSTRIAL SCALE SCREENING OF 1.3 MILLION COMPOUNDS IDENTIFIED 14 NOVEL CHEMOTYPES AS PROMISING NEW LEADS FOR THE TREATMENT OF LYMPHATIC FILARIASIS AND ONCHOCERCIASIS: A COLLABORATION BETWEEN THE ANTI-WOLBACHIA CONSORTIUM AND ASTRAZENECA (Conference Paper)
Clare, R. H., Bardelle, C., Berry, N., Harper, P., Borjesson, U., O'Neill, P., . . . Ward, S. A. (2017). INDUSTRIAL SCALE SCREENING OF 1.3 MILLION COMPOUNDS IDENTIFIED 14 NOVEL CHEMOTYPES AS PROMISING NEW LEADS FOR THE TREATMENT OF LYMPHATIC FILARIASIS AND ONCHOCERCIASIS: A COLLABORATION BETWEEN THE ANTI-WOLBACHIA CONSORTIUM AND ASTRAZENECA. In AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Vol. 95 (pp. 153-154). Retrieved from https://www.webofscience.com/
Vivek, J. P., Berry, N. G., Zou, J., Nichols, R. J., & Hardwick, L. J. (2017). In Situ Surface-Enhanced Infrared Spectroscopy to Identify Oxygen Reduction Products in Nonaqueous Metal-Oxygen Batteries. JOURNAL OF PHYSICAL CHEMISTRY C, 121(36), 19657-19667. doi:10.1021/acs.jpcc.7b06391DOI: 10.1021/acs.jpcc.7b06391
Johnston, K. L., Cook, D. A. N., Berry, N. G., Hong, W. D., Clare, R. H., Goddard, M., . . . Taylor, M. J. (2017). Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library. SCIENCE ADVANCES, 3(09). doi:10.1126/sciadv.aao1551DOI: 10.1126/sciadv.aao1551
Hong, W. D., Gibbons, P. D., Leung, S. C., Amewu, R., Stocks, P. A., Stachulski, A. V., . . . Nixon, G. L. (2017). Rational Design, Synthesis and Biological Evaluation of Heterocyclic Quinolones Targeting the respiratory chain of Mycobacterium tuberculosis.. Journal of medicinal chemistry, 60(9), 3703-3726. doi:10.1021/acs.jmedchem.6b01718DOI: 10.1021/acs.jmedchem.6b01718
2016
Price, K. E., Armstrong, C. M., Imlay, L. S., Hodge, D. M., Pidathala, C., Roberts, N. J., . . . Odom John, A. R. (2016). Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD. Scientific Reports, 6. doi:10.1038/srep36777DOI: 10.1038/srep36777
Gupta, J. K., Adams, D. J., & Berry, N. G. (2016). Will it gel? Successful computational prediction of peptide gelators using physicochemical properties and molecular fingerprints. CHEMICAL SCIENCE, 7(7), 4713-4719. doi:10.1039/c6sc00722hDOI: 10.1039/c6sc00722h
Wong, M. H. L., Bryan, H. K., Copple, I. M., Jenkins, R. E., Chiu, P. H., Bibby, J., . . . Park, B. K. (2016). Design and Synthesis of Irreversible Analogues of Bardoxolone Methyl for the Identification of Pharmacologically Relevant Targets and Interaction Sites. JOURNAL OF MEDICINAL CHEMISTRY, 59(6), 2396-2409. doi:10.1021/acs.jmedchem.5b01292DOI: 10.1021/acs.jmedchem.5b01292
Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute Pancreatitis (Journal article)
Shore, E. R., Awais, M., Kershaw, N. M., Gibson, R. R., Pandalanen, S., Latawiec, D., . . . Sutton, R. (2016). Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute Pancreatitis. JOURNAL OF MEDICINAL CHEMISTRY, 59(06), 2596-2611. doi:10.1021/acs.jmedchem.5b01801DOI: 10.1021/acs.jmedchem.5b01801
Vivek, J. P., Berry, N., Papageorgiou, G., Nichols, R. J., & Hardwick, L. J. (2016). Mechanistic Insight into the Superoxide Induced Ring Opening in Propylene Carbonate Based Electrolytes using in Situ Surface-Enhanced Infrared Spectroscopy. Journal of the American Chemical Society, 138(11), 3745-3751. doi:10.1021/jacs.5b12494DOI: 10.1021/jacs.5b12494
2015
Towards depersonalized abacavir therapy: chemical modification eliminates HLA-B*57 : 01-restricted CD8+ T-cell activation (Journal article)
Naisbitt, D., Yang, E. L., Alhaidari, M., Berry, N., Lawrenson, A. S., Farrell, J., . . . Park, B. (2015). Towards depersonalized abacavir therapy: chemical modification eliminates HLA-B*57 : 01-restricted CD8+ T-cell activation. AIDS, 29(18), 2385-2395. doi:10.1097/QAD.0000000000000867DOI: 10.1097/QAD.0000000000000867
Carbamoyl triazoles, Known Serine Protease Inhibitors, are a potent New Class of Antimalarial (Journal article)
O'Neill, P., McConville, M., Fernandez-molina, J., Angulo-Barturen, I., Bahamontes, N. R., Ballell-Pages, L., . . . Calderon, F. (2015). Carbamoyl triazoles, Known Serine Protease Inhibitors, are a potent New Class of Antimalarial. Journal of Medicinal Chemistry, 58(16), 6448-6455. doi:10.1021/acs.jmedchem.5b00434DOI: 10.1021/acs.jmedchem.5b00434
2-Pyridylquinolone antimalarials with improved antimalarial activity and physicochemical properties (Journal article)
Charoensutthivarakul, S., Hong, W. D., Leung, S. C., Gibbons, P. D., Bedingfield, P. T. P., Nixon, G. L., . . . O'Neill, P. M. (2015). 2-Pyridylquinolone antimalarials with improved antimalarial activity and physicochemical properties. MEDCHEMCOMM, 6(7), 1252-1259. doi:10.1039/c5md00062aDOI: 10.1039/c5md00062a
<i>Plasmodium</i> IspD (2-C-Methyl-D-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target (Journal article)
Imlay, L. S., Armstrong, C. M., Masters, M. C., Li, T., Price, K. E., Edwards, R. L., . . . Odom, A. R. (2015). <i>Plasmodium</i> IspD (2-C-Methyl-D-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target. ACS INFECTIOUS DISEASES, 1(4), 157-167. doi:10.1021/id500047sDOI: 10.1021/id500047s
Capper, M., O'Neill, P., Fisher, N., Strange, R., Moss, D., Ward, S., . . . Antonyuk, S. (2015). Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1. Proceedings of the National Academy of Sciences of the United States of America, 112(3), 755-760. doi:10.1073/pnas.1416611112DOI: 10.1073/pnas.1416611112
<i>ANTI- WOLBACHIA</i> ( A- WOL) DRUG DISCOVERY: LIGAND BASED VIRTUAL SCREENING COMBINED WITH HTS (Conference Paper)
Berry, N., O'Neill, P., Bibby, J., Ward, S., & Taylor, M. (2015). <i>ANTI- WOLBACHIA</i> ( A- WOL) DRUG DISCOVERY: LIGAND BASED VIRTUAL SCREENING COMBINED WITH HTS. In AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Vol. 93 (pp. 526). Retrieved from https://www.webofscience.com/
Small Molecule Inhibitors of Cyclophilin D to Protect Mitochondrial Function as a Possible Treatment for Acute Pancreatitis (Journal article)
Awais, M., Shore, E., Gibson, R., Javed, M. A., Wen, L., Latawiec, D., . . . Sutton, R. (2015). Small Molecule Inhibitors of Cyclophilin D to Protect Mitochondrial Function as a Possible Treatment for Acute Pancreatitis. PANCREAS, 44(8), 1360. Retrieved from https://www.webofscience.com/
2014
ChemInform Abstract: The Synthesis and Structure of Chiral Enamine N‐Oxides. (Journal article)
O'Neil, I. A., McConville, M., Zhou, K., Brooke, C., Robertson, C. M., & Berry, N. G. (2014). ChemInform Abstract: The Synthesis and Structure of Chiral Enamine N‐Oxides.. ChemInform, 45(48). doi:10.1002/chin.201448115DOI: 10.1002/chin.201448115
Abacavir forms novel cross-linking abacavir protein adducts in patients (Journal article)
Meng, X., Lawrenson, A., Berry, N., Maggs, J., French, N., Back, D., . . . Park, K. (2014). Abacavir forms novel cross-linking abacavir protein adducts in patients. Clinical and translational allergy, 4(Suppl 3), P38. doi:10.1186/2045-7022-4-s3-p38DOI: 10.1186/2045-7022-4-s3-p38
Chemical modification of the 6'‐amino cyclopropyl of abacavir eliminates HLA‐B*57:01‐restricted CD8+ T‐cell activation without loss of antiviral activity (Journal article)
Alhaidari, M., Yang, E., Berry, N., Owen, A., Clarke, S., O'Neill, P., . . . Park, K. (2014). Chemical modification of the 6'‐amino cyclopropyl of abacavir eliminates HLA‐B*57:01‐restricted CD8+ T‐cell activation without loss of antiviral activity. Clinical and Translational Allergy, 4(S3). doi:10.1186/2045-7022-4-s3-p40DOI: 10.1186/2045-7022-4-s3-p40
The synthesis and structure of chiral enamine N-oxides (Journal article)
O'Neil, I. A., McConville, M., Zhou, K., Brooke, C., Robertson, C. M., & Berry, N. G. (2014). The synthesis and structure of chiral enamine N-oxides. Chemical Communications, 50(55), 7336-7339. doi:10.1039/c3cc47928eDOI: 10.1039/c3cc47928e
Abacavir forms novel cross-linking abacavir protein adducts in patients (Journal article)
Meng, X., Lawrenson, A. S., Berry, N. G., Maggs, J. L., French, N. S., Back, D. J., . . . Park, B. K. (2014). Abacavir forms novel cross-linking abacavir protein adducts in patients. Chemical Research in Toxicology, 27(04), 524-535. doi:10.1021/tx400406pDOI: 10.1021/tx400406p
Side-chain control of porosity closure in single- and multiple-peptide-based porous materials by cooperative folding (Journal article)
Martí-Gastaldo, C., Antypov, D., Warren, J., Briggs, M., Chater, P., Wiper, P., . . . Rosseinsky, M. (2014). Side-chain control of porosity closure in single- and multiple-peptide-based porous materials by cooperative folding. Nature Chemistry, 6, 343-351. doi:10.1038/nchem.1871DOI: 10.1038/nchem.1871
Guest Adaptable and Water Stable Peptide Based Porous Materials by Imidazolate Sidechain Control (Journal article)
Katsoulidis, A. P., Park, K. S., Antypov, D., Marti-Gastaldo, C., Miller, G. P., Warren, J. E., . . . Rosseinsky, M. J. (2014). Guest Adaptable and Water Stable Peptide Based Porous Materials by Imidazolate Sidechain Control. Angew. Chem. Int. Ed., 53, 193-198.
Katsoulidis, A., Park, K. S., Antypov, D., Martí-Gastaldo, C., Miller, G., Warren, J., . . . Rosseinsky, M. (2014). Guest-Adaptable and Water-Stable Peptide-Based Porous Materials by Imidazolate Side Chain Control. Angewandte Chemie International Edition, 53(1), 193-198. doi:10.1002/anie.201307074DOI: 10.1002/anie.201307074
Guest‐Adaptable and Water‐Stable Peptide‐Based Porous Materials by Imidazolate Side Chain Control (Journal article)
Katsoulidis, A. P., Park, K. S., Antypov, D., Martí‐Gastaldo, C., Miller, G. J., Warren, J. E., . . . Rosseinsky, M. J. (2014). Guest‐Adaptable and Water‐Stable Peptide‐Based Porous Materials by Imidazolate Side Chain Control. Angewandte Chemie, 126(1), 197-202. doi:10.1002/ange.201307074DOI: 10.1002/ange.201307074
4-bromopropofol decreases action potential generation in spinal neurons by inducing a glycine receptor-mediated tonic conductance (Journal article)
Eckle, V. S., Grasshoff, C., Mirakaj, V., O'Neill, P. M., Berry, N. G., Leuwer, M., & Antkowiak, B. (2014). 4-bromopropofol decreases action potential generation in spinal neurons by inducing a glycine receptor-mediated tonic conductance. BRITISH JOURNAL OF PHARMACOLOGY, 171(24), 5790-5801. doi:10.1111/bph.12880DOI: 10.1111/bph.12880
2013
Artemisinin-Polypyrrole Conjugates: Synthesis, DNA Binding Studies and Preliminary Antiproliferative Evaluation (Journal article)
La Pensee, L., Sabbani, S., Sharma, R., Bhamra, I., Shore, E., Chadwick, A. E., . . . O'Neill, P. M. (2013). Artemisinin-Polypyrrole Conjugates: Synthesis, DNA Binding Studies and Preliminary Antiproliferative Evaluation. CHEMMEDCHEM, 8(5), 709-718. doi:10.1002/cmdc.201200536DOI: 10.1002/cmdc.201200536
Inside Cover: Artemisinin–Polypyrrole Conjugates: Synthesis, DNA Binding Studies and Preliminary Antiproliferative Evaluation (ChemMedChem 5/2013) (Journal article)
La Pensée, L., Sabbani, S., Sharma, R., Bhamra, I., Shore, E., Chadwick, A. E., . . . O'Neill, P. M. (2013). Inside Cover: Artemisinin–Polypyrrole Conjugates: Synthesis, DNA Binding Studies and Preliminary Antiproliferative Evaluation (ChemMedChem 5/2013). ChemMedChem, 8(5), 674. doi:10.1002/cmdc.201390016DOI: 10.1002/cmdc.201390016
Antitubercular pharmacodynamics of phenothiazines (Journal article)
Warman, A. J., Rito, T. S., Fisher, N. E., Moss, D. M., Berry, N. G., O'Neill, P. M., . . . Biagini, G. A. (2013). Antitubercular pharmacodynamics of phenothiazines. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 68(4), 869-880. doi:10.1093/jac/dks483DOI: 10.1093/jac/dks483
Antitubercular pharmacodynamics of phenothiazines (Journal article)
Warman, A. J., Rito, T. S., Fisher, N. E., Moss, D. M., Berry, N. G., O'Neill, P. M., . . . Biagini, G. A. (2013). Antitubercular pharmacodynamics of phenothiazines. Journal of Antimicrobial Chemotherapy, 68(4), 869-880. doi:10.1093/jac/dks483DOI: 10.1093/jac/dks483
Long-range metal-ligand bifunctional catalysis: cyclometallated iridium catalysts for the mild and rapid dehydrogenation of formic acid (Journal article)
Barnard, J. H., Wang, C., Berry, N. G., & Xiao, J. (2013). Long-range metal-ligand bifunctional catalysis: cyclometallated iridium catalysts for the mild and rapid dehydrogenation of formic acid. CHEMICAL SCIENCE, 4(3), 1234-1244. doi:10.1039/c2sc21923aDOI: 10.1039/c2sc21923a
Cooperative Catalysis through Noncovalent Interactions (Journal article)
Tang, W., Johnston, S., Iggo, J. A., Berry, N. G., Phelan, M., Lian, L., . . . Xiao, J. (2013). Cooperative Catalysis through Noncovalent Interactions. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 52(6), 1668-1672. doi:10.1002/anie.201208774DOI: 10.1002/anie.201208774
Cooperative Catalysis through Noncovalent Interactions (Journal article)
Tang, W., Johnston, S., Iggo, J. A., Berry, N. G., Phelan, M., Lian, L., . . . Xiao, J. (2013). Cooperative Catalysis through Noncovalent Interactions. Angewandte Chemie, 125(6), 1712-1716. doi:10.1002/ange.201208774DOI: 10.1002/ange.201208774
Cooperative Catalysis through Noncovalent Interactions (Journal article)
Tang, W., Johnston, S., Iggo, J. A., Berry, N. G., Phelan, M., Lian, L., . . . Xiao, J. (2013). Cooperative Catalysis through Noncovalent Interactions. Angewandte Chemie International Edition, 52(6), 1668-1672. doi:10.1002/anie.201208774DOI: 10.1002/anie.201208774
Development of Small Molecule Inhibitors of Cyclophilin D for Treatment of Severe Acute Pancreatitis (Journal article)
Awais, M., Javed, M. A., Wen, L., Gibson, R., Shore, E., Kershaw, N., . . . Sutton, R. (2013). Development of Small Molecule Inhibitors of Cyclophilin D for Treatment of Severe Acute Pancreatitis. PANCREAS, 42(8), 1338. Retrieved from https://www.webofscience.com/
X-ray Crystallography and Computational Docking for the Detection and Development of Protein-Ligand Interactions (Journal article)
Kershaw, N. M., Wright, G. S. A., Sharma, R., Antonyuk, S. V., Strange, R. W., Berry, N. G., . . . Hasnain, S. S. (2013). X-ray Crystallography and Computational Docking for the Detection and Development of Protein-Ligand Interactions. CURRENT MEDICINAL CHEMISTRY, 20(4), 569-575. Retrieved from https://www.webofscience.com/
X-ray Crystallography and Computational Docking for the Detection and Development of Protein-Ligand Interactions (Journal article)
Kershaw, N. M., Wright, G. S. A., Sharma, R., Antonyuk, S. V., Strange, R. W., Berry, N. G., . . . Hasnain, S. S. (2013). X-ray Crystallography and Computational Docking for the Detection and Development of Protein-Ligand Interactions. Current Medicinal Chemistry, 20(4), 569-575.
2012
ChemInform Abstract: Chiral Bicyclic [2.2.2] Octadiene Ligands for Rh‐Catalyzed Catalytic Asymmetric Conjugate Additions to Acyclic Enones: A Quantitative Structure—Property Relationship. (Journal article)
Luo, Y., Berry, N. G., & Carnell, A. J. (2012). ChemInform Abstract: Chiral Bicyclic [2.2.2] Octadiene Ligands for Rh‐Catalyzed Catalytic Asymmetric Conjugate Additions to Acyclic Enones: A Quantitative Structure—Property Relationship.. ChemInform, 43(31). doi:10.1002/chin.201231019DOI: 10.1002/chin.201231019
HDQ, a Potent Inhibitor of <i>Plasmodium falciparum</i> Proliferation, Binds to the Quinone Reduction Site of the Cytochrome <i>bc</i><sub>1</sub> Complex (Journal article)
Vallieres, C., Fisher, N., Antoine, T., Al-Helal, M., Stocks, P., Berry, N. G., . . . Meunier, B. (2012). HDQ, a Potent Inhibitor of <i>Plasmodium falciparum</i> Proliferation, Binds to the Quinone Reduction Site of the Cytochrome <i>bc</i><sub>1</sub> Complex. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 56(7), 3739-3747. doi:10.1128/AAC.00486-12DOI: 10.1128/AAC.00486-12
Generation of quinolone antimalarials targeting the <i>Plasmodium falciparum</i> mitochondrial respiratory chain for the treatment and prophylaxis of malaria (Journal article)
Biagini, G. A., Fisher, N., Shone, A. E., Mubaraki, M. A., Srivastava, A., Hill, A., . . . Ward, S. A. (2012). Generation of quinolone antimalarials targeting the <i>Plasmodium falciparum</i> mitochondrial respiratory chain for the treatment and prophylaxis of malaria. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(21), 8298-8303. doi:10.1073/pnas.1205651109DOI: 10.1073/pnas.1205651109
Identification of Novel Antimalarial Chemotypes via Chemoinformatic Compound Selection Methods for a High-Throughput Screening Program against the Novel Malarial Target, PfNDH2: Increasing Hit Rate via Virtual Screening Methods (Journal article)
Sharma, R., Lawrenson, A. S., Fisher, N. E., Warman, A. J., Shone, A. E., Hill, A., . . . Berry, N. G. (2012). Identification of Novel Antimalarial Chemotypes via Chemoinformatic Compound Selection Methods for a High-Throughput Screening Program against the Novel Malarial Target, PfNDH2: Increasing Hit Rate via Virtual Screening Methods. JOURNAL OF MEDICINAL CHEMISTRY, 55(7), 3144-3154. doi:10.1021/jm3001482DOI: 10.1021/jm3001482
Chiral bicyclic [2.2.2] octadiene ligands for Rh-catalysed catalytic asymmetric conjugate additions to acyclic enones: a quantitative structure-property relationship (Journal article)
Luo, Y., Berry, N. G., & Carnell, A. J. (2012). Chiral bicyclic [2.2.2] octadiene ligands for Rh-catalysed catalytic asymmetric conjugate additions to acyclic enones: a quantitative structure-property relationship. CHEMICAL COMMUNICATIONS, 48(27), 3279-3281. doi:10.1039/c2cc17120aDOI: 10.1039/c2cc17120a
The MEP pathway and the development of inhibitors as potential anti-infective agents (Journal article)
Hale, I., O'Neill, P. M., Berry, N. G., Odom, A., & Sharma, R. (2012). The MEP pathway and the development of inhibitors as potential anti-infective agents. MEDCHEMCOMM, 3(4), 418-433. doi:10.1039/c2md00298aDOI: 10.1039/c2md00298a
Identification, Design and Biological Evaluation of Bisaryl Quinolones Targeting <i>Plasmodium falciparum</i> Type II NADH:Quinone Oxidoreductase (PfNDH2) (Journal article)
Pidathala, C., Amewu, R., Pacorel, B., Nixon, G. L., Gibbons, P., Hong, W. D., . . . O'Neill, P. M. (2012). Identification, Design and Biological Evaluation of Bisaryl Quinolones Targeting <i>Plasmodium falciparum</i> Type II NADH:Quinone Oxidoreductase (PfNDH2). JOURNAL OF MEDICINAL CHEMISTRY, 55(5), 1831-1843. doi:10.1021/jm201179hDOI: 10.1021/jm201179h
Identification, Design and Biological Evaluation of Heterocyclic Quinolones Targeting <i>Plasmodium falciparum</i> Type II NADH:Quinone Oxidoreductase (PfNDH2) (Journal article)
Leung, S. C., Gibbons, P., Amewu, R., Nixon, G. L., Pidathala, C., Hong, W. D., . . . O'Neill, P. M. (2012). Identification, Design and Biological Evaluation of Heterocyclic Quinolones Targeting <i>Plasmodium falciparum</i> Type II NADH:Quinone Oxidoreductase (PfNDH2). JOURNAL OF MEDICINAL CHEMISTRY, 55(5), 1844-1857. doi:10.1021/jm201184hDOI: 10.1021/jm201184h
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain (Journal article)
Shone, A. E., Fisher, N., Mubaraki, M. A., Srivastava, A., Hill, A., Antoine, T., . . . Berry, N. (2012). Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain. Proceedings of the National Academy of Sciences of the United States of America, (109), 8298-8303.
HDQ, A Potent Inhibitor Of Plasmodium Falciparum Proliferation Binds To The Qi Site Of The Bc1 Complex (Journal article)
Vallières, C., Fisher, N., Antoine, T., Al-Helal, M., Stocks, P., Berry, N. G., . . . Meunier, B. (2012). HDQ, A Potent Inhibitor Of Plasmodium Falciparum Proliferation Binds To The Qi Site Of The Bc1 Complex. Antimicrobial Agents and Chemotherapy, 56, 3739-3747.
The development of quinolone esters as novel antimalarial agents targeting the <i>Plasmodium falciparum bc</i><sub>1</sub> protein complex (Journal article)
Cowley, R., Leung, S., Fisher, N., Al-Helal, M., Berry, N. G., Lawrenson, A. S., . . . O'Neill, P. M. (2012). The development of quinolone esters as novel antimalarial agents targeting the <i>Plasmodium falciparum bc</i><sub>1</sub> protein complex. MEDCHEMCOMM, 3(1), 39-44. doi:10.1039/c1md00183cDOI: 10.1039/c1md00183c
The development of quinoloneesters as novel antimalarial agents targeting the Plasmodium falciparum bc<sub>1</sub>protein complex (Journal article)
Cowley, R., Leung, S., Fisher, N., Al-Helal, M., Berry, N. G., Lawrenson, A. S., . . . O′Neill, P. M. (n.d.). The development of quinoloneesters as novel antimalarial agents targeting the Plasmodium falciparum bc<sub>1</sub>protein complex. Med. Chem. Commun., 3(1), 39-44. doi:10.1039/c1md00183cDOI: 10.1039/c1md00183c
2011
Thiazolides as Novel Antiviral Agents. 2. Inhibition of Hepatitis C Virus Replication (Journal article)
Stachulski, A. V., Pidathala, C., Row, E. C., Sharma, R., Berry, N. G., Lawrenson, A. S., . . . Rossignol, J. -F. (2011). Thiazolides as Novel Antiviral Agents. 2. Inhibition of Hepatitis C Virus Replication. JOURNAL OF MEDICINAL CHEMISTRY, 54(24), 8670-8680. doi:10.1021/jm201264tDOI: 10.1021/jm201264t
Thiazolides as Novel Antiviral Agents. 2. Inhibition of Hepatitis C Virus Replication (Journal article)
Stachulski, A. V., Pidathala, C., Row, E. C., Sharma, R., Berry, N. G., Lawrenson, A. S., . . . Rossignol, J. -F. (2011). Thiazolides as Novel Antiviral Agents. 2. Inhibition of Hepatitis C Virus Replication. Journal of Medicinal Chemistry, 54(24), 8670-8680. doi:10.1021/jm201264tDOI: 10.1021/jm201264t
Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins (Journal article)
Antonyuk, S. V., Rustage, N., Petersen, C. A., Arnst, J. L., Heyes, D. J., Sharma, R., . . . Hasnain, S. S. (2011). Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(38), 15780-15785. doi:10.1073/pnas.1109051108DOI: 10.1073/pnas.1109051108
Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients (Journal article)
Meng, X., Jenkins, R. E., Berry, N. G., Maggs, J. L., Farrell, J., Lane, C. S., . . . Park, B. K. (2011). Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients. Journal of Pharmacology and Experimental Therapeutics, 338(3), 841-849. doi:10.1124/jpet.111.183871DOI: 10.1124/jpet.111.183871
Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients (Journal article)
Meng, X., Jenkins, R. E., Berry, N. G., Maggs, J. L., Farrell, J., Lane, C. S., . . . Park, B. K. (2011). Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 338(3), 841-849. doi:10.1124/jpet.111.183871DOI: 10.1124/jpet.111.183871
Antimalarial Mannoxanes: Hybrid Antimalarial Drugs with Outstanding Oral Activity Profiles and A Potential Dual Mechanism of Action (Journal article)
Chadwick, J., Amewu, R. K., Marti, F., Bousejra-El Garah, F., Sharma, R., Berry, N. G., . . . O'Neill, P. M. (2011). Antimalarial Mannoxanes: Hybrid Antimalarial Drugs with Outstanding Oral Activity Profiles and A Potential Dual Mechanism of Action. CHEMMEDCHEM, 6(8), 1357-1361. doi:10.1002/cmdc.201100196DOI: 10.1002/cmdc.201100196
Unusual Hybrid Materials Prepared by the Oxidation of a Ketone (Journal article)
Holden, D. L., Goulding, H. V., Bacsa, J., Berry, N. G., Greeves, N., Stephenson, R. A., . . . Fogg, A. M. (2011). Unusual Hybrid Materials Prepared by the Oxidation of a Ketone. Crystal Growth & Design, 11(7), 3013-3019. doi:10.1021/cg200286tDOI: 10.1021/cg200286t
Unusual Hybrid Materials Prepared by the Oxidation of a Ketone (Journal article)
Holden, D. L., Goulding, H. V., Bacsa, J., Berry, N. G., Greeves, N., Stephenson, R. A., . . . Fogg, A. M. (2011). Unusual Hybrid Materials Prepared by the Oxidation of a Ketone. CRYSTAL GROWTH & DESIGN, 11(7), 3013-3019. doi:10.1021/cg200286tDOI: 10.1021/cg200286t
Second generation analogues of RKA182: synthetic tetraoxanes with outstanding <i>in vitro</i> and <i>in vivo</i> antimalarial activities (Journal article)
Marti, F., Chadwick, J., Amewu, R. K., Burrell-Saward, H., Srivastava, A., Ward, S. A., . . . O'Neill, P. M. (2011). Second generation analogues of RKA182: synthetic tetraoxanes with outstanding <i>in vitro</i> and <i>in vivo</i> antimalarial activities. MEDCHEMCOMM, 2(7), 661-665. doi:10.1039/c1md00102gDOI: 10.1039/c1md00102g
Thiazolides as Novel Antiviral Agents. 1. Inhibition of Hepatitis B Virus Replication (Journal article)
Stachulski, A. V., Pidathala, C., Row, E. C., Sharma, R., Berry, N. G., Iqbal, M., . . . Rossignol, J. -F. (2011). Thiazolides as Novel Antiviral Agents. 1. Inhibition of Hepatitis B Virus Replication. JOURNAL OF MEDICINAL CHEMISTRY, 54(12), 4119-4132. doi:10.1021/jm200153pDOI: 10.1021/jm200153p
ChemInform Abstract: Hydrogen‐Bonding‐Promoted Oxidative Addition and Regioselective Arylation of Olefins with Aryl Chlorides. (Journal article)
Ruan, J., Iggo, J. A., Berry, N. G., & Xiao, J. (2011). ChemInform Abstract: Hydrogen‐Bonding‐Promoted Oxidative Addition and Regioselective Arylation of Olefins with Aryl Chlorides.. ChemInform, 42(19). doi:10.1002/chin.201119071DOI: 10.1002/chin.201119071
Antimalarial Mannoxanes: Hybrid Antimalarial Drugs with Outstanding Oral Activity Profiles and A Potential Dual Mechanism of Action (Journal article)
Chadwick, J., Amewu, R. K., Marti, F., Bousejra-El Garah, F., Sharma, R., Berry, N. G., . . . O'Neill, P. M. (2011). Antimalarial Mannoxanes: Hybrid Antimalarial Drugs with Outstanding Oral Activity Profiles and A Potential Dual Mechanism of Action. Chemmedchem, 6, 1357-1361.
ChemPreLab (Journal article)
Sedghi, G., Berry, N., & Greeves, N. (2011). ChemPreLab. Wavelength, 7(1), 42-43.
ChemPreLab: Chemistry pre-lab virtual experiments (Conference Paper)
Sedghi, G., Berry, N., Greeves, N., & Barnes, K. (2011). ChemPreLab: Chemistry pre-lab virtual experiments. In Variety Conference. York.
Providing Recordings of Chemistry Teaching (Journal article)
Berry, N., Greeves, N., Aspinall, H., Bunyan, N., Barnes, K., Bradford, M., & Chin, P. (2011). Providing Recordings of Chemistry Teaching. Wavelength, 7(1), 6-9.
Thiazolides as Novel Antiviral Agents. 1. Inhibition of Hepatitis B Virus Replication (Journal article)
Stachulski, A. V., Pidathala, C., Row, E. C., Sharma, R., Berry, N. G., Iqbal, M., . . . Rossignol, J. -F. (2011). Thiazolides as Novel Antiviral Agents. 1. Inhibition of Hepatitis B Virus Replication. Journal of Medicinal Chemistry,, 54, 4119-4132.
2010
Hydrogen-Bonding-Promoted Oxidative Addition and Regioselective Arylation of Olefins with Aryl Chlorides (Journal article)
Ruan, J., Iggo, J. A., Berry, N. G., & Xiao, J. (2010). Hydrogen-Bonding-Promoted Oxidative Addition and Regioselective Arylation of Olefins with Aryl Chlorides. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(46), 16689-16699. doi:10.1021/ja1081926DOI: 10.1021/ja1081926
An Adaptable Peptide-Based Porous Material (Journal article)
Rabone, J., Yue, Y. -F., Chong, S. Y., Stylianou, K. C., Bacsa, J., Bradshaw, D., . . . Rosseinsky, M. J. (2010). An Adaptable Peptide-Based Porous Material. SCIENCE, 329(5995), 1053-1057. doi:10.1126/science.1190672DOI: 10.1126/science.1190672
A novel drug for uncomplicated malaria: Targeted high throughput screening (HTS) against the type II NADH:ubiquinone oxidoreductase (PfNDH2) of <i>Plasmodium falciparum</i> (Journal article)
Fisher, N., Hill, A., Mbekeani, A., Shone, A., Nixon, G., Stocks, P., . . . Biagini, G. A. (2010). A novel drug for uncomplicated malaria: Targeted high throughput screening (HTS) against the type II NADH:ubiquinone oxidoreductase (PfNDH2) of <i>Plasmodium falciparum</i>. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1797, 80. doi:10.1016/j.bbabio.2010.04.241DOI: 10.1016/j.bbabio.2010.04.241
The type II NADH: Quinone oxidoreductase of <i>Mycobacterium tuberculosis</i>: A novel drug target for an age-old problem (Journal article)
Warman, A. J., Rito, T., Fisher, N., Berry, N. G., O'Neill, P. M., Ward, S. A., & Biagini, G. A. (2010). The type II NADH: Quinone oxidoreductase of <i>Mycobacterium tuberculosis</i>: A novel drug target for an age-old problem. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1797, 117-118. doi:10.1016/j.bbabio.2010.04.352DOI: 10.1016/j.bbabio.2010.04.352
A novel drug for uncomplicated malaria: targeted high throughput screening (HTS) against the type II NADH:ubiquinone oxidoreductase (PfNdh2) of Plasmodium falciparum (Journal article)
Ward, S. A., Fisher, N., Hill, A., Mbekeani, A., Shone, A., Nixon, G., . . . Biagini, G. A. (2010). A novel drug for uncomplicated malaria: targeted high throughput screening (HTS) against the type II NADH:ubiquinone oxidoreductase (PfNdh2) of Plasmodium falciparum. Malaria journal, 9(Suppl 2), I14. doi:10.1186/1475-2875-9-s2-i14DOI: 10.1186/1475-2875-9-s2-i14
ChemTube3D Interactive 3D Organic Reaction Mechanisms (Software / Code)
Greeves, N., & Berry, N. G. (2010). ChemTube3D Interactive 3D Organic Reaction Mechanisms (Version 2.0) [Internet (free access)]. Liverpool. Retrieved from http://www.chemtube3d.com/
Development of a novel drug for uncomplicated malaria targeting the mitochondrial NADH:quinone oxidoreductase (Journal article)
Biagini, G. A., Hill, A., Mbekeani, A., Shone, A., Nixon, G., Stocks, P., . . . Ward, S. A. (2010). Development of a novel drug for uncomplicated malaria targeting the mitochondrial NADH:quinone oxidoreductase. Malaria journal, 9(Suppl 2), O4. doi:10.1186/1475-2875-9-s2-o4DOI: 10.1186/1475-2875-9-s2-o4
Stimulation of human T cells with sulfonamides and sulfonamide metabolites (Journal article)
Castrejon, J. L., Berry, N., El-Ghaiesh, S., Gerber, B., Pichler, W. J., Park, B. K., & Naisbitt, D. J. (2010). Stimulation of human T cells with sulfonamides and sulfonamide metabolites. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 125(2), 411-418. doi:10.1016/j.jaci.2009.10.031DOI: 10.1016/j.jaci.2009.10.031
Supporting lifelong learning: enhancing the value of interactive 3D chemistry (Report)
Barnes, K., Greeves, N., Berry, N., Bunyan, N., & Strivens, J. (2010). Supporting lifelong learning: enhancing the value of interactive 3D chemistry. Bristol: JISC. Retrieved from http://www.jisc.ac.uk/whatwedo/programmes/elearning/ltig/ichem3d.aspx
2009
Synthesis, transacylation kinetics and computational chemistry of a set of arylacetic acid 1β-<i>O</i>-acyl glucuronides (Journal article)
Berry, N. G., Iddon, L., Iqbal, M., Meng, X., Jayapal, P., Johnson, C. H., . . . Stachulski, A. V. (2009). Synthesis, transacylation kinetics and computational chemistry of a set of arylacetic acid 1β-<i>O</i>-acyl glucuronides. ORGANIC & BIOMOLECULAR CHEMISTRY, 7(12), 2525-2533. doi:10.1039/b822777bDOI: 10.1039/b822777b
ChemInform Abstract: Electron‐Deficient Phosphines Accelerate the Heck Reaction of Electron‐Rich Olefins in Ionic Liquid. (Journal article)
Liu, S., Saidi, O., Berry, N., Ruan, J., Pettman, A., Thomson, N., & Xiao, J. (2009). ChemInform Abstract: Electron‐Deficient Phosphines Accelerate the Heck Reaction of Electron‐Rich Olefins in Ionic Liquid.. ChemInform, 40(23). doi:10.1002/chin.200923053DOI: 10.1002/chin.200923053
Synthesis, Antimalarial Activity, and Preclinical Pharmacology of a Novel Series of 4′-Fluoro and 4′-Chloro Analogues of Amodiaquine. Identification of a Suitable "Back-Up" Compound for <i>N-tert</i>-Butyl Isoquine (Journal article)
O'Neill, P. M., Shone, A. E., Stanford, D., Nixon, G., Asadollahy, E., Park, B. K., . . . Ward, S. A. (2009). Synthesis, Antimalarial Activity, and Preclinical Pharmacology of a Novel Series of 4′-Fluoro and 4′-Chloro Analogues of Amodiaquine. Identification of a Suitable "Back-Up" Compound for <i>N-tert</i>-Butyl Isoquine. JOURNAL OF MEDICINAL CHEMISTRY, 52(7), 1828-1844. doi:10.1021/jm8012757DOI: 10.1021/jm8012757
Electron-Deficient Phosphines Accelerate the Heck Reaction of Electronrich Olefins in Ionic Liquid (Journal article)
Liu, S., Saidi, O., Berry, N., Ruan, J., Pettman, A., Thomson, N., & Xiao, J. (2009). Electron-Deficient Phosphines Accelerate the Heck Reaction of Electronrich Olefins in Ionic Liquid. LETTERS IN ORGANIC CHEMISTRY, 6(1), 60-64. doi:10.2174/157017809787003052DOI: 10.2174/157017809787003052
Electron-Deficient Phosphines Accelerate the Heck Reaction of Electronrich Olefins in Ionic Liquid (Journal article)
Liu, S., Saidi, O., Berry, N., Ruan, J., Pettman, A., Thomson, N., & Xiao, J. (2009). Electron-Deficient Phosphines Accelerate the Heck Reaction of Electronrich Olefins in Ionic Liquid. Letters in Organic Chemistry, 6(1), 60-64. Retrieved from http://www.scopus.com/inward/record.url?eid=2-s2.0-69249199741&partnerID=40
2008
Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors (Journal article)
Verissimo, E., Berry, N., Gibbons, P., Cristiano, M. L. S., Rosenthal, P. J., Gut, J., . . . O'Neill, P. M. (2008). Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 18(14), 4210-4214. doi:10.1016/j.bmcl.2008.05.068DOI: 10.1016/j.bmcl.2008.05.068
Acridinediones: Selective and Potent Inhibitors of the Malaria Parasite Mitochondrial<i>bc</i><sub>1</sub>Complex (Journal article)
Biagini, G. A., Fisher, N., Berry, N., Stocks, P. A., Meunier, B., Williams, D. P., . . . Ward, S. A. (2008). Acridinediones: Selective and Potent Inhibitors of the Malaria Parasite Mitochondrial<i>bc</i><sub>1</sub>Complex. Molecular Pharmacology, 73(5), 1347-1355. doi:10.1124/mol.108.045120DOI: 10.1124/mol.108.045120
Acridinediones:: Selective and potent inhibitors of the malaria parasite mitochondrial <i>bc</i><sub>1</sub> complex (Journal article)
Biagini, G. A., Fisher, N., Berry, N., Stocks, P. A., Meunier, B., Williams, D. P., . . . Ward, S. A. (2008). Acridinediones:: Selective and potent inhibitors of the malaria parasite mitochondrial <i>bc</i><sub>1</sub> complex. MOLECULAR PHARMACOLOGY, 73(5), 1347-1355. doi:10.1124/mol.108.045120DOI: 10.1124/mol.108.045120
Acridinediones:: a new class of potent inhibitors selective against the mitochondrial bc1 complex of the malaria parasite <i>Plasmodium falciparum</i>. (Conference Paper)
Biagini, G. A., Fisher, N., Berry, N., Stocks, P., Meunier, B., Bray, P. G., . . . Ward, S. A. (2008). Acridinediones:: a new class of potent inhibitors selective against the mitochondrial bc1 complex of the malaria parasite <i>Plasmodium falciparum</i>.. In INTERNATIONAL JOURNAL FOR PARASITOLOGY Vol. 38 (pp. S41). Retrieved from https://www.webofscience.com/
2007
Design and Synthesis of Orally Active Dispiro 1,2,4,5‐Tetraoxanes; Synthetic Antimalarials with Superior Activity to Artemisinin. (Journal article)
Amewu, R., Stachulski, A. V., Ward, S. A., Berry, N. G., Bray, P. G., Davies, J., . . . O'Neill, P. M. (2007). Design and Synthesis of Orally Active Dispiro 1,2,4,5‐Tetraoxanes; Synthetic Antimalarials with Superior Activity to Artemisinin.. ChemInform, 38(13). doi:10.1002/chin.200713173DOI: 10.1002/chin.200713173
Synthesis of 1,2,4‐Trioxepanes via Application of Thiol‐Olefin Co‐Oxygenation Methodology. (Journal article)
Amewu, R., Stachulski, A. V., Berry, N. G., Ward, S. A., Davies, J., Labat, G., . . . O'Neill, P. M. (2007). Synthesis of 1,2,4‐Trioxepanes via Application of Thiol‐Olefin Co‐Oxygenation Methodology.. ChemInform, 38(11). doi:10.1002/chin.200711148DOI: 10.1002/chin.200711148
Back matter (Journal article)
Back matter (2007). Organic & Biomolecular Chemistry, 5(4), 708. doi:10.1039/b701157cDOI: 10.1039/b701157c
Pd—mBDPP‐Catalyzed Regioselective Internal Arylation of Electron‐Rich Olefins by Aryl Halides. (Journal article)
Liu, S., Berry, N., Thomson, N., Pettman, A., Hyder, Z., Mo, J., & Xiao, J. (2007). Pd—mBDPP‐Catalyzed Regioselective Internal Arylation of Electron‐Rich Olefins by Aryl Halides.. ChemInform, 38(5). doi:10.1002/chin.200705043DOI: 10.1002/chin.200705043
Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin (vol 4, pg 4431, 2006) (Journal article)
Amewu, R., Stachulski, A. V., Ward, S. A., Berry, N. G., Bray, P. G., Davies, J., . . . O'Neill, P. M. (2007). Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin (vol 4, pg 4431, 2006). ORGANIC & BIOMOLECULAR CHEMISTRY, 5(4), 708. Retrieved from https://www.webofscience.com/
NMR studies of the conformational effect of single and double 3′-<i>S</i>-phosphorothiolate substitutions within deoxythymidine trinucleotides (Journal article)
Jayakumar, H. K., Buckingham, J. L., Brazier, J. A., Berry, N. G., Cosstick, R., & Fisher, J. (2007). NMR studies of the conformational effect of single and double 3′-<i>S</i>-phosphorothiolate substitutions within deoxythymidine trinucleotides. MAGNETIC RESONANCE IN CHEMISTRY, 45(4), 340-345. doi:10.1002/mrc.1977DOI: 10.1002/mrc.1977
2006
Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin (Journal article)
Amewu, R., Stachulski, A. V., Ward, S. A., Berry, N. G., Bray, P. G., Davies, J., . . . O'Neill, P. M. (2006). Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin. ORGANIC & BIOMOLECULAR CHEMISTRY, 4(24), 4431-4436. doi:10.1039/b613565jDOI: 10.1039/b613565j
Synthesis of 1,2,4-trioxepanes via application of thiol-olefin Co-oxygenation methodology (Journal article)
Amewu, R., Stachulski, A. V., Berry, N. G., Ward, S. A., Davies, J., Labat, G., . . . O'Neill, P. M. (2006). Synthesis of 1,2,4-trioxepanes via application of thiol-olefin Co-oxygenation methodology. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16(23), 6124-6130. doi:10.1016/j.bmcl.2006.08.098DOI: 10.1016/j.bmcl.2006.08.098
A Family of Nanoporous Materials Based on an Amino Acid Backbone (Journal article)
Vaidhyanathan, R., Bradshaw, D., Rebilly, J., Barrio, J. P., Gould, J. A., Berry, N. G., & Rosseinsky, M. J. (2006). A Family of Nanoporous Materials Based on an Amino Acid Backbone. Angewandte Chemie, 118(39), 6645-6649. doi:10.1002/ange.200602242DOI: 10.1002/ange.200602242
A family of nanoporous materials based on an amino acid backbone (Journal article)
Vaidhyanathan, R., Bradshaw, D., Rebilly, J. -N., Barrio, J. P., Gould, J. A., Berry, N. G., & Rosseinsky, M. J. (2006). A family of nanoporous materials based on an amino acid backbone. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 45(39), 6495-6499. doi:10.1002/anie.200602242DOI: 10.1002/anie.200602242
Pd-mBDPP-catalyzed regioselective internal arylation of electron-rich olefins by aryl halides (Journal article)
Liu, S., Berry, N., Thomson, N., Pettman, A., Hyder, Z., Mo, J., & Xiao, J. (2006). Pd-mBDPP-catalyzed regioselective internal arylation of electron-rich olefins by aryl halides. JOURNAL OF ORGANIC CHEMISTRY, 71(19), 7467-7470. doi:10.1021/jo0609632DOI: 10.1021/jo0609632
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs (Journal article)
O'Neill, P. M., Ward, S. A., Berry, N. G., Jeyadevan, J. P., Biagini, G. A., Asadollaly, E., . . . Bray, P. G. (2006). A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 6(5), 479-507. doi:10.2174/156802606776743147DOI: 10.2174/156802606776743147
Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo (Journal article)
Stachulski, A. V., Berry, N. G., Low, A. C. L., Moores, S. L., Row, E., Warhurst, D. C., . . . Rossignol, J. F. (2006). Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo. JOURNAL OF MEDICINAL CHEMISTRY, 49(4), 1450-1454. doi:10.1021/jm050973fDOI: 10.1021/jm050973f
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs (Journal article)
O'Neill, P. M., Ward, S. A., Berry, N. G., Jeyadevan, J. P., Biagini, G. A., Asadollaly, E., . . . Bray, P. G. (2006). A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs. Current Topics in Medicinal Chemistry, 6(5), 479-507. Retrieved from http://www.scopus.com/inward/record.url?eid=2-s2.0-33646202766&partnerID=40
2005
In vitro efficacies of nitazoxanide and other thiazolides against <i>Neospora caninum</i> tachyzoites reveal antiparasitic activity independent of the nitro group (Journal article)
Esposito, M., Stettler, R., Moores, S. L., Pidathala, C., Müller, N., Stachulski, A., . . . Hemphill, A. (2005). In vitro efficacies of nitazoxanide and other thiazolides against <i>Neospora caninum</i> tachyzoites reveal antiparasitic activity independent of the nitro group. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 49(9), 3715-3723. doi:10.1128/AAC.49.9.3715-3723.2005DOI: 10.1128/AAC.49.9.3715-3723.2005
Characterization of the T-cell response in a patient with phenindione hypersensitivity (Journal article)
Naisbitt, D. J., Farrell, J., Chamberlain, P. J., Hopkins, J. E., Berry, N. G., Pirmohamed, M., & Park, B. K. (2005). Characterization of the T-cell response in a patient with phenindione hypersensitivity. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 313(3), 1058-1065. doi:10.1124/jpet.105.083758DOI: 10.1124/jpet.105.083758
The design and synthesis of novel anomeric hydroperoxides: influence of the carbohydrate residue in the enantioselective epoxidation of quinones (Journal article)
Bundu, A., Berry, N. G., Gill, C. D., Dxyer, C. L., Stachulski, A. V., Taylor, R. J. K., & Whittall, J. (2005). The design and synthesis of novel anomeric hydroperoxides: influence of the carbohydrate residue in the enantioselective epoxidation of quinones. TETRAHEDRON-ASYMMETRY, 16(1), 283-293. doi:10.1016/j.tetasy.2004.11.015DOI: 10.1016/j.tetasy.2004.11.015
2003
Metal-directed self-assembly of bimetallic dithiocarbamate transition metal cryptands and their binding capabilities (Journal article)
Beer, P. D., Berry, N. G., Cowley, A. R., Hayes, E. J., Oates, E. C., & Wong, W. W. H. (2003). Metal-directed self-assembly of bimetallic dithiocarbamate transition metal cryptands and their binding capabilities. CHEMICAL COMMUNICATIONS, (19), 2408-2409. doi:10.1039/b308629aDOI: 10.1039/b308629a
2002
Anion recognition as a method for templating pseudorotaxane formation (Journal article)
Wisner, J. A., Beer, P. D., Berry, N. G., & Tomapatanaget, B. (2002). Anion recognition as a method for templating pseudorotaxane formation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 99(8), 4983-4986. doi:10.1073/pnas.062637999DOI: 10.1073/pnas.062637999
Heteroditopic Transition Metal Dithiocarbamate Receptors for Binding Cation-Anion Ion Pairs (Journal article)
Berry, N. G., Shimell, T. W., & Beer, P. D. (2002). Heteroditopic Transition Metal Dithiocarbamate Receptors for Binding Cation-Anion Ion Pairs. Journal of Supramolecular Chemistry, 2(1-3), 89-92. doi:10.1016/s1472-7862(02)00083-7DOI: 10.1016/s1472-7862(02)00083-7
2001
Self-assembled dithiocarbamate-copper(II) macrocycles for electrochemical anion recognition (Journal article)
Beer, P. D., Berry, N., Drew, M. G. B., Fox, O. D., Padilla-Tosta, M. E., & Patell, S. (2001). Self-assembled dithiocarbamate-copper(II) macrocycles for electrochemical anion recognition. CHEMICAL COMMUNICATIONS, (2), 199-200. doi:10.1039/b007296fDOI: 10.1039/b007296f
Transition metal self-assembly of dithiocarbamate based anion receptors (Journal article)
Berry, N. G., Pratt, M. D., Fox, O. D., & Beer, P. D. (2001). Transition metal self-assembly of dithiocarbamate based anion receptors. SUPRAMOLECULAR CHEMISTRY, 13(6), 677-682. doi:10.1080/10610270108027497DOI: 10.1080/10610270108027497
