Professor John Bower

Regius Chair of Chemistry Chemistry

Publications

2021

Selective Carbon-Carbon Bond Cleavage of Cyclopropylamine Derivatives. (Journal article)

Sokolova, O. O., & Bower, J. F. (2021). Selective Carbon-Carbon Bond Cleavage of Cyclopropylamine Derivatives.. Chemical Reviews, 121(1), 80-109. doi:10.1021/acs.chemrev.0c00166

DOI: 10.1021/acs.chemrev.0c00166

2020

Carbonylative C-C Bond Activation of Aminocyclopropanes Using a Temporary Directing Group Strategy (Journal article)

Wang, G. -W., Sokolova, O. O., Young, T. A., Christodoulou, E. M. S., Butts, C. P., & Bower, J. F. (2020). Carbonylative C-C Bond Activation of Aminocyclopropanes Using a Temporary Directing Group Strategy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 142(45), 19006-19011. doi:10.1021/jacs.0c08973

DOI: 10.1021/jacs.0c08973

Naphthoquinones and derivatives for chemotherapy: perspectives and limitations of their anti-trypanosomatids activities. (Journal article)

Dantas-Pereira, L., Cunha-Junior, E. F., Andrade-Neto, V. V., Bower, J. F., Jardim, G. A. M., da Silva Júnior, E. N., . . . Menna-Barreto, R. F. S. (2020). Naphthoquinones and derivatives for chemotherapy: perspectives and limitations of their anti-trypanosomatids activities.. Current pharmaceutical design. doi:10.2174/1381612826666201109111802

DOI: 10.2174/1381612826666201109111802

Recent Methodologies That Exploit Oxidative Addition of C-N Bonds to Transition Metals (Journal article)

Garcia-Carceles, J., Bahou, K. A., & Bower, J. F. (2020). Recent Methodologies That Exploit Oxidative Addition of C-N Bonds to Transition Metals. ACS CATALYSIS, 10(21), 12738-12759. doi:10.1021/acscatal.0c03341

DOI: 10.1021/acscatal.0c03341

Strategies towards potent trypanocidal drugs: Application of Rh-catalyzed [2?+?2?+?2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi (Journal article)

Wood, J. M., Satam, N. S., Almeida, R. G., Cristani, V. S., de Lima, D. P., Dantas-Pereira, L., . . . da Silva Júnior, E. N. (2020). Strategies towards potent trypanocidal drugs: Application of Rh-catalyzed [2?+?2?+?2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi. Bioorganic and Medicinal Chemistry, 28(15). doi:10.1016/j.bmc.2020.115565

DOI: 10.1016/j.bmc.2020.115565

Pseudo-enantiomeric carbohydrate-based N-heterocyclic carbenes as promising chiral ligands for enantiotopic discrimination (Journal article)

Henderson, A. S., Bower, J. F., & Galan, M. C. (2020). Pseudo-enantiomeric carbohydrate-based N-heterocyclic carbenes as promising chiral ligands for enantiotopic discrimination. ORGANIC & BIOMOLECULAR CHEMISTRY, 18(16), 3012-3016. doi:10.1039/d0ob00155d

DOI: 10.1039/d0ob00155d

Oxidative Addition of Alkenyl and Alkynyl Iodides to a Au-I Complex (Journal article)

Cadge, J. A., Sparkes, H. A., Bower, J. F., & Russell, C. A. (2020). Oxidative Addition of Alkenyl and Alkynyl Iodides to a Au-I Complex. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 59(16), 6617-6621. doi:10.1002/anie.202000473

DOI: 10.1002/anie.202000473

Rhodacyclopentanones as Linchpins for the Atom Economical Assembly of Diverse Polyheterocycles (Journal article)

Wang, G. -W., Boyd, O., Young, T. A., Bertrand, S. M., & Bower, J. F. (2020). Rhodacyclopentanones as Linchpins for the Atom Economical Assembly of Diverse Polyheterocycles. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 142(4), 1740-1745. doi:10.1021/jacs.9b12421

DOI: 10.1021/jacs.9b12421

Rh-Catalyzed [2+2+2] Cycloadditions with Benzoquinones: De Novo Access to Naphthoquinones for Lignan and Type II Polyketide Synthesis (Journal article)

Wood, J. M., da Silva Junior, E. N., & Bower, J. F. (2020). Rh-Catalyzed [2+2+2] Cycloadditions with Benzoquinones: De Novo Access to Naphthoquinones for Lignan and Type II Polyketide Synthesis. ORGANIC LETTERS, 22(1), 265-269. doi:10.1021/acs.orglett.9b04266

DOI: 10.1021/acs.orglett.9b04266

2019

Modular Access to Eight-Membered N-Heterocycles by Directed Carbonylative C-C Bond Activation of Aminocyclopropanes (Journal article)

Boyd, O., Wang, G. -W., Sokolova, O. O., Calow, A. D. J., Bertrand, S. M., & Bower, J. F. (2019). Modular Access to Eight-Membered N-Heterocycles by Directed Carbonylative C-C Bond Activation of Aminocyclopropanes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 58(52), 18844-18848. doi:10.1002/anie.201910276

DOI: 10.1002/anie.201910276

Enantioselective Aza-Heck Cyclizations of N-(Tosyloxy)carbamates: Synthesis of Pyrrolidines and Piperidines (Journal article)

Ma, X., Hazelden, I. R., Langer, T., Munday, R. H., & Bower, J. F. (2019). Enantioselective Aza-Heck Cyclizations of N-(Tosyloxy)carbamates: Synthesis of Pyrrolidines and Piperidines. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 141(8), 3356-3360. doi:10.1021/jacs.8b12689

DOI: 10.1021/jacs.8b12689

Carbonylative C-C Bond Activation of Electron-Poor Cyclopropanes: Rhodium-Catalyzed (3+1+2) Cycloadditions of Cyclopropylamides (Journal article)

Dalling, A. G., Yamauchi, T., McCreanor, N. G., Cox, L., & Bower, J. F. (2019). Carbonylative C-C Bond Activation of Electron-Poor Cyclopropanes: Rhodium-Catalyzed (3+1+2) Cycloadditions of Cyclopropylamides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 58(1), 221-225. doi:10.1002/anie.201811460

DOI: 10.1002/anie.201811460

2018

Stereospecific Alkene Aziridination Using a Bifunctional Amino-Reagent: An Aza-Prilezhaev Reaction (Journal article)

Farndon, J. J., Young, T. A., & Bower, J. F. (2018). Stereospecific Alkene Aziridination Using a Bifunctional Amino-Reagent: An Aza-Prilezhaev Reaction. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 140(51), 17846-17850. doi:10.1021/jacs.8b10485

DOI: 10.1021/jacs.8b10485

Iridium-Catalyzed alpha-Selective Arylation of Styrenes by Dual C-H Functionalization (Journal article)

Cooper, P., Crisenza, G. E. M., Feron, L. J., & Bower, J. F. (2018). Iridium-Catalyzed alpha-Selective Arylation of Styrenes by Dual C-H Functionalization. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 57(43), 14198-14202. doi:10.1002/anie.201808299

DOI: 10.1002/anie.201808299

Synthesis of Nitrogen Heterocycles via Directed Carbonylative C-C Bond Activation of Cyclopropanes (Journal article)

Dalling, A. G., & Bower, J. F. (2018). Synthesis of Nitrogen Heterocycles via Directed Carbonylative C-C Bond Activation of Cyclopropanes. CHIMIA, 72(9), 595-600. doi:10.2533/chimia.2018.595

DOI: 10.2533/chimia.2018.595

Branch-Selective and Enantioselective Iridium-Catalyzed Alkene Hydroarylation via Anilide-Directed C-H Oxidative Addition (Journal article)

Grelaud, S., Cooper, P., Feron, L. J., & Bower, J. F. (2018). Branch-Selective and Enantioselective Iridium-Catalyzed Alkene Hydroarylation via Anilide-Directed C-H Oxidative Addition. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 140(30), 9351-9356. doi:10.1021/jacs.8b04627

DOI: 10.1021/jacs.8b04627

Pyrrolidines and Piperidines by Ligand-Enabled Aza-Heck Cyclizations and Cascades of N-(Pentafluorobenzoyloxy)carbamates (Journal article)

Hazelden, I. R., Carmona, R. C., Langer, T., Pringle, P. G., & Bower, J. F. (2018). Pyrrolidines and Piperidines by Ligand-Enabled Aza-Heck Cyclizations and Cascades of N-(Pentafluorobenzoyloxy)carbamates. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 57(18), 5124-5128. doi:10.1002/anie.201801109

DOI: 10.1002/anie.201801109

Oxidative Addition, Transmetalation, and Reductive Elimination at a 2,2 '-Bipyridyl-Ligated Gold Center (Journal article)

Harper, M. J., Arthur, C. J., Crosby, J., Emmett, E. J., Falconer, R. L., Fensham-Smith, A. J., . . . Russell, C. A. (2018). Oxidative Addition, Transmetalation, and Reductive Elimination at a 2,2 '-Bipyridyl-Ligated Gold Center. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 140(12), 4440-4445. doi:10.1021/jacs.8b01411

DOI: 10.1021/jacs.8b01411

Modular Access to Azepines by Directed Carbonylative C-C Bond Activation of Aminocyclopropanes (Journal article)

Wang, G. -W., & Bower, J. F. (2018). Modular Access to Azepines by Directed Carbonylative C-C Bond Activation of Aminocyclopropanes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 140(8), 2743-2747. doi:10.1021/jacs.7b13087

DOI: 10.1021/jacs.7b13087

2017

A Simple and Broadly Applicable C-N Bond Forming Dearomatization Protocol Enabled by Bifunctional Amino Reagents (Journal article)

Ma, X., Farndon, J. J., Young, T. A., Fey, N., & Bower, J. F. (2017). A Simple and Broadly Applicable C-N Bond Forming Dearomatization Protocol Enabled by Bifunctional Amino Reagents. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 56(46), 14531-14535. doi:10.1002/anie.201708176

DOI: 10.1002/anie.201708176

Reductive Coupling of Acrylates with Ketones and Ketimines by a Nickel-Catalyzed Transfer-Hydrogenative Strategy (Journal article)

Buxton, C. S., Blakemore, D. C., & Bower, J. F. (2017). Reductive Coupling of Acrylates with Ketones and Ketimines by a Nickel-Catalyzed Transfer-Hydrogenative Strategy. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 56(44), 13824-13828. doi:10.1002/anie.201707531

DOI: 10.1002/anie.201707531

Transition Metal Free C-N Bond Forming Dearomatizations and Aryl C-H Aminations by in Situ Release of a Hydroxylamine-Based Aminating Agent (Journal article)

Farndon, J. J., Ma, X., & Bower, J. F. (2017). Transition Metal Free C-N Bond Forming Dearomatizations and Aryl C-H Aminations by in Situ Release of a Hydroxylamine-Based Aminating Agent. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139(40), 14005-14008. doi:10.1021/jacs.7b07830

DOI: 10.1021/jacs.7b07830

Oxidative 1,2-Difunctionalization of Ethylene via Gold-Catalyzed Oxyarylation (Journal article)

Harper, M. J., Emmett, E. J., Bower, J. F., & Russell, C. A. (2017). Oxidative 1,2-Difunctionalization of Ethylene via Gold-Catalyzed Oxyarylation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139(36), 12386-12389. doi:10.1021/jacs.7b06668

DOI: 10.1021/jacs.7b06668

Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti-Trypanosoma cruzi activities and electrochemical studies of functionalized quinones (Journal article)

Jardim, G. A. M., Silva, T. L., Goulart, M. O. F., de Simone, C. A., Barbosa, J. M. C., Salomao, K., . . . da Silva Junior, E. N. (2017). Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti-Trypanosoma cruzi activities and electrochemical studies of functionalized quinones. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 136, 406-419. doi:10.1016/j.ejmech.2017.05.011

DOI: 10.1016/j.ejmech.2017.05.011

Recent developments in the use of aza-Heck cyclizations for the synthesis of chiral N-heterocycles (Journal article)

Race, N. J., Hazelden, I. R., Faulkner, A., & Bower, J. F. (2017). Recent developments in the use of aza-Heck cyclizations for the synthesis of chiral N-heterocycles. CHEMICAL SCIENCE, 8(8), 5248-5260. doi:10.1039/c7sc01480e

DOI: 10.1039/c7sc01480e

Recent Methodologies That Exploit C-C Single-Bond Cleavage of Strained Ring Systems by Transition Metal Complexes (Journal article)

Fumagalli, G., Stanton, S., & Bower, J. F. (2017). Recent Methodologies That Exploit C-C Single-Bond Cleavage of Strained Ring Systems by Transition Metal Complexes. CHEMICAL REVIEWS, 117(13), 9404-9432. doi:10.1021/acs.chemrev.6b00599

DOI: 10.1021/acs.chemrev.6b00599

Enantioselective Narasaka-Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters (Journal article)

Race, N. J., Faulkner, A., Fumagalli, G., Yamauchi, T., Scott, J. S., Ryden-Landergren, M., . . . Bower, J. F. (2017). Enantioselective Narasaka-Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters. CHEMICAL SCIENCE, 8(3), 1981-1985. doi:10.1039/c6sc04466b

DOI: 10.1039/c6sc04466b

2016

New Initiation Modes for Directed Carbonylative C-C Bond Activation: Rhodium-Catalyzed (3+1+2) Cycloadditions of Aminomethylcyclopropanes (Journal article)

Wang, G. -W., McCreanor, N. G., Shaw, M. H., Whittingham, W. G., & Bower, J. F. (2016). New Initiation Modes for Directed Carbonylative C-C Bond Activation: Rhodium-Catalyzed (3+1+2) Cycloadditions of Aminomethylcyclopropanes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 138(41), 13501-13504. doi:10.1021/jacs.6b08608

DOI: 10.1021/jacs.6b08608

Synthesis and applications of rhodacyclopentanones derived from C-C bond activation (Journal article)

Shaw, M. H., & Bower, J. F. (2016). Synthesis and applications of rhodacyclopentanones derived from C-C bond activation. CHEMICAL COMMUNICATIONS, 52(72), 10817-10829. doi:10.1039/c6cc04359c

DOI: 10.1039/c6cc04359c

Rh-Catalyzed Reactions of 1,4-Benzoquinones with Electrophiles: C-H Iodination, Bromination, and Phenylselenation (Journal article)

Jardim, G. A. M., Bower, J. F., & da Silva Junior, E. N. (2016). Rh-Catalyzed Reactions of 1,4-Benzoquinones with Electrophiles: C-H Iodination, Bromination, and Phenylselenation. ORGANIC LETTERS, 18(18), 4454-4457. doi:10.1021/acs.orglett.6b01586

DOI: 10.1021/acs.orglett.6b01586

Capture-Collapse Heterocyclization: 1,3-Diazepanes by C-N Reductive Elimination from Rhodacyclopentanones (Journal article)

McCreanor, N. G., Stanton, S., & Bower, J. F. (2016). Capture-Collapse Heterocyclization: 1,3-Diazepanes by C-N Reductive Elimination from Rhodacyclopentanones. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 138(36), 11465-11468. doi:10.1021/jacs.6b07046

DOI: 10.1021/jacs.6b07046

Diverse N-Heterocyclic Ring Systems via Aza-Heck Cyclizations of N-(Pentafluorobenzoyloxy)sulfonamides (Journal article)

Hazelden, I. R., Ma, X., Langer, T., & Bower, J. F. (2016). Diverse N-Heterocyclic Ring Systems via Aza-Heck Cyclizations of N-(Pentafluorobenzoyloxy)sulfonamides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 55(37), 11198-11202. doi:10.1002/anie.201605152

DOI: 10.1002/anie.201605152

Catalytic chirality generation: new strategies for heterocyclic chemistry (Conference Paper)

Bower, J. (2016). Catalytic chirality generation: new strategies for heterocyclic chemistry. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 252. Retrieved from http://gateway.webofknowledge.com/

C2-Alkenylation of N-heteroaromatic compounds via Bronsted acid catalysis (Journal article)

Crisenza, G. E. M., Dauncey, E. M., & Bower, J. F. (2016). C2-Alkenylation of N-heteroaromatic compounds via Bronsted acid catalysis. ORGANIC & BIOMOLECULAR CHEMISTRY, 14(24), 5820-5825. doi:10.1039/c6ob00705h

DOI: 10.1039/c6ob00705h

Directed carbonylative (3+1+2) cycloadditions of amino-substituted cyclopropanes and alkynes: reaction development and increased efficiencies using a cationic rhodium system (Journal article)

Shaw, M. H., Whittingham, W. G., & Bower, J. E. (2016). Directed carbonylative (3+1+2) cycloadditions of amino-substituted cyclopropanes and alkynes: reaction development and increased efficiencies using a cationic rhodium system. TETRAHEDRON, 72(22), 2731-2741. doi:10.1016/j.tet.2015.08.052

DOI: 10.1016/j.tet.2015.08.052

Overcoming naphthoquinone deactivation: rhodium-catalyzed C-5 selective C-H iodination as a gateway to functionalized derivatives (Journal article)

Jardim, G. A. M., da Silva Junior, E. N., & Bower, J. F. (2016). Overcoming naphthoquinone deactivation: rhodium-catalyzed C-5 selective C-H iodination as a gateway to functionalized derivatives. CHEMICAL SCIENCE, 7(6), 3780-3784. doi:10.1039/c6sc00302h

DOI: 10.1039/c6sc00302h

Carbohydrates as enantioinduction components in stereoselective catalysis (Journal article)

Henderson, A. S., Bower, J. F., & Galan, M. C. (2016). Carbohydrates as enantioinduction components in stereoselective catalysis. ORGANIC & BIOMOLECULAR CHEMISTRY, 14(17), 4008-4017. doi:10.1039/c6ob00368k

DOI: 10.1039/c6ob00368k

Dichotomous mechanistic behavior in Narasaka-Heck cyclizations: electron rich Pd-catalysts generate iminyl radicals (Journal article)

Race, N. J., Faulkner, A., Shaw, M. H., & Bower, J. F. (2016). Dichotomous mechanistic behavior in Narasaka-Heck cyclizations: electron rich Pd-catalysts generate iminyl radicals. CHEMICAL SCIENCE, 7(2), 1508-1513. doi:10.1039/c5sc04037j

DOI: 10.1039/c5sc04037j

Branch Selective Mural-type Alkene Hydroarylation Reactions (Journal article)

Crisenza, G. E. M., & Bower, J. F. (2016). Branch Selective Mural-type Alkene Hydroarylation Reactions. CHEMISTRY LETTERS, 45(1), 2-9. doi:10.1246/cl.150913

DOI: 10.1246/cl.150913

2015

Branch-Selective Alkene Hydroarylation by Cooperative Destabilization: Iridium-Catalyzed ortho-Alkylation of Acetanilides (Journal article)

Crisenza, G. E. M., Sokolova, O. O., & Bower, J. F. (2015). Branch-Selective Alkene Hydroarylation by Cooperative Destabilization: Iridium-Catalyzed ortho-Alkylation of Acetanilides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 54(49), 14866-14870. doi:10.1002/anie.201506581

DOI: 10.1002/anie.201506581

Nucleophilic Aromatic Substitution (SNAr) as an Approach to Challenging Carbohydrate-Aryl Ethers (Journal article)

Henderson, A. S., Medina, S., Bower, J. F., & Galan, M. C. (2015). Nucleophilic Aromatic Substitution (SNAr) as an Approach to Challenging Carbohydrate-Aryl Ethers. ORGANIC LETTERS, 17(19), 4846-4849. doi:10.1021/acs.orglett.5b02413

DOI: 10.1021/acs.orglett.5b02413

Modular Access to Substituted Azocanes via a Rhodium-Catalyzed Cycloaddition-Fragmentation Strategy (Journal article)

Shaw, M. H., Croft, R. A., Whittingham, W. G., & Bower, J. F. (2015). Modular Access to Substituted Azocanes via a Rhodium-Catalyzed Cycloaddition-Fragmentation Strategy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137(25), 8054-8057. doi:10.1021/jacs.5b05215

DOI: 10.1021/jacs.5b05215

An Umpolung Approach to Alkene Carboamination: Palladium Catalyzed 1,2-Amino-Acylation, -Carboxylation, -Arylation, -Vinylation, and -Alkynylation (Journal article)

Faulkner, A., Scott, J. S., & Bower, J. F. (2015). An Umpolung Approach to Alkene Carboamination: Palladium Catalyzed 1,2-Amino-Acylation, -Carboxylation, -Arylation, -Vinylation, and -Alkynylation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137(22), 7224-7230. doi:10.1021/jacs.5b03732

DOI: 10.1021/jacs.5b03732

Stereoselective synthesis of glycosides using (salen)Co catalysts as promoters (Journal article)

Medina, S., Henderson, A. S., Bower, J. F., & Galan, M. C. (2015). Stereoselective synthesis of glycosides using (salen)Co catalysts as promoters. CHEMICAL COMMUNICATIONS, 51(43), 8939-8941. doi:10.1039/c5cc02552d

DOI: 10.1039/c5cc02552d

Reversible C-C Bond Activation Enables Stereocontrol in Rh-Catalyzed Carbonylative Cycloadditions of Aminocyclopropanes (Journal article)

Shaw, M. H., McCreanor, N. G., Whittingham, W. G., & Bower, J. F. (2015). Reversible C-C Bond Activation Enables Stereocontrol in Rh-Catalyzed Carbonylative Cycloadditions of Aminocyclopropanes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137(1), 463-468. doi:10.1021/ja511335v

DOI: 10.1021/ja511335v

2014

Carbohydrate-based N-heterocyclic carbenes for enantioselective catalysis (Journal article)

Henderson, A. S., Bower, J. F., & Galan, M. C. (2014). Carbohydrate-based N-heterocyclic carbenes for enantioselective catalysis. ORGANIC & BIOMOLECULAR CHEMISTRY, 12(45), 9180-9183. doi:10.1039/c4ob02056a

DOI: 10.1039/c4ob02056a

Branch-Selective, Iridium-Catalyzed Hydroarylation of Monosubstituted Alkenes via a Cooperative Destabilization Strategy (Journal article)

Crisenza, G. E. M., McCreanor, N. G., & Bower, J. F. (2014). Branch-Selective, Iridium-Catalyzed Hydroarylation of Monosubstituted Alkenes via a Cooperative Destabilization Strategy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(29), 10258-10261. doi:10.1021/ja505776m

DOI: 10.1021/ja505776m

Copper catalyzed Heck-like cyclizations of oxime esters (Journal article)

Faulkner, A., Race, N. J., Scott, J. S., & Bower, J. F. (2014). Copper catalyzed Heck-like cyclizations of oxime esters. CHEMICAL SCIENCE, 5(6), 2416-2421. doi:10.1039/c4sc00652f

DOI: 10.1039/c4sc00652f

2013

Palladium Catalyzed Cyclizations of Oxime Esters with 1,2-Disubstituted Alkenes: Synthesis of Dihydropyrroles (Journal article)

Race, N. J., & Bower, J. F. (2013). Palladium Catalyzed Cyclizations of Oxime Esters with 1,2-Disubstituted Alkenes: Synthesis of Dihydropyrroles. ORGANIC LETTERS, 15(17), 4616-4619. doi:10.1021/ol4023112

DOI: 10.1021/ol4023112

Directing Group Enhanced Carbonylative Ring Expansions of Amino-Substituted Cyclopropanes: Rhodium-Catalyzed Multicomponent Synthesis of N-Heterobicyclic Enones (Journal article)

Shaw, M. H., Melikhova, E. Y., Kloer, D. P., Whittingham, W. G., & Bower, J. F. (2013). Directing Group Enhanced Carbonylative Ring Expansions of Amino-Substituted Cyclopropanes: Rhodium-Catalyzed Multicomponent Synthesis of N-Heterobicyclic Enones. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 135(13), 4992-4995. doi:10.1021/ja401936c

DOI: 10.1021/ja401936c

A Robust First-Pass Protocol for the Heck-Mizoroki Reaction (Journal article)

Murray, P. M., Bower, J. F., Cox, D. K., Galbraith, E. K., Parker, J. S., & Sweeney, J. B. (2013). A Robust First-Pass Protocol for the Heck-Mizoroki Reaction. ORGANIC PROCESS RESEARCH & DEVELOPMENT, 17(3), 397-405. doi:10.1021/op300364p

DOI: 10.1021/op300364p

Palladium catalyzed cyclizations of oxime esters with 1,1-disubstituted alkenes: synthesis of alpha,alpha-disubstituted dihydropyrroles and studies towards an asymmetric protocol (Journal article)

Faulkner, A., Scott, J. S., & Bower, J. F. (2013). Palladium catalyzed cyclizations of oxime esters with 1,1-disubstituted alkenes: synthesis of alpha,alpha-disubstituted dihydropyrroles and studies towards an asymmetric protocol. CHEMICAL COMMUNICATIONS, 49(15), 1521-1523. doi:10.1039/c2cc38944d

DOI: 10.1039/c2cc38944d

Catalytic chirality generation: new strategies for N-heterocyclic chemistry (Conference Paper)

Bower, J. F. (2013). Catalytic chirality generation: new strategies for N-heterocyclic chemistry. In JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS Vol. 56 (pp. 55). Retrieved from http://gateway.webofknowledge.com/

2012

Olefin cross-metathesis for the synthesis of heteroaromatic compounds (Journal article)

Donohoe, T. J., Bower, J. F., & Chan, L. K. M. (2012). Olefin cross-metathesis for the synthesis of heteroaromatic compounds. ORGANIC & BIOMOLECULAR CHEMISTRY, 10(7), 1322-1328. doi:10.1039/c2ob06659a

DOI: 10.1039/c2ob06659a

Highly Efficient Narasaka-Heck Cyclizations Mediated by P(3,5-(CF3)2C6H3)3: Facile Access to N-Heterobicyclic Scaffolds (Journal article)

Faulkner, A., & Bower, J. F. (2012). Highly Efficient Narasaka-Heck Cyclizations Mediated by P(3,5-(CF3)2C6H3)3: Facile Access to N-Heterobicyclic Scaffolds. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 51(7), 1675-1679. doi:10.1002/anie.201107511

DOI: 10.1002/anie.201107511

2011

Synthesis of 2,4,6-trisubstituted pyridines via an olefin cross-metathesis/Heck-cyclisation-elimination sequence (Journal article)

Donohoe, T. J., Bower, J. F., Baker, D. B., Basutto, J. A., Chan, L. K. M., & Gallagher, P. (2011). Synthesis of 2,4,6-trisubstituted pyridines via an olefin cross-metathesis/Heck-cyclisation-elimination sequence. CHEMICAL COMMUNICATIONS, 47(38), 10611-10613. doi:10.1039/c1cc14257g

DOI: 10.1039/c1cc14257g

Heteroaromatic Synthesis via Olefin Cross-Metathesis: Entry to Polysubstituted Pyridines (Journal article)

Donohoe, T. J., Basutto, J. A., Bower, J. F., & Rathi, A. (2011). Heteroaromatic Synthesis via Olefin Cross-Metathesis: Entry to Polysubstituted Pyridines. ORGANIC LETTERS, 13(5), 1036-1039. doi:10.1021/ol103088r

DOI: 10.1021/ol103088r

Formation of C-C Bonds via Iridium-Catalyzed Hydrogenation and Transfer Hydrogenation (Journal article)

Bower, J. F., & Krische, M. J. (2011). Formation of C-C Bonds via Iridium-Catalyzed Hydrogenation and Transfer Hydrogenation. IRIDIUM CATALYSIS, 34, 107-138. doi:10.1007/978-3-642-15334-1_5

DOI: 10.1007/978-3-642-15334-1_5

2010

Olefin cross-metathesis-based approaches to furans: procedures for the preparation of di- and trisubstituted variants (Journal article)

Donohoe, T. J., Bower, J. F., & Basutto, J. A. (2010). Olefin cross-metathesis-based approaches to furans: procedures for the preparation of di- and trisubstituted variants. NATURE PROTOCOLS, 5(12), 2005-2010. doi:10.1038/nprot.2010.147

DOI: 10.1038/nprot.2010.147

Substituted Pyrroles via Olefin Cross-Metathesis (Journal article)

Donohoe, T. J., Race, N. J., Bower, J. F., & Callens, C. K. A. (2010). Substituted Pyrroles via Olefin Cross-Metathesis. ORGANIC LETTERS, 12(18), 4094-4097. doi:10.1021/ol101681r

DOI: 10.1021/ol101681r

N-Heterocycle construction via cyclic sulfamidates. Applications in synthesis (Journal article)

Bower, J. F., Rujirawanicha, J., & Gallagher, T. (2010). N-Heterocycle construction via cyclic sulfamidates. Applications in synthesis. ORGANIC & BIOMOLECULAR CHEMISTRY, 8(7), 1505-1519. doi:10.1039/b921842d

DOI: 10.1039/b921842d

An expedient route to substituted furans via olefin cross-metathesis (Journal article)

Donohoe, T. J., & Bower, J. F. (2010). An expedient route to substituted furans via olefin cross-metathesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(8), 3373-3376. doi:10.1073/pnas.0913466107

DOI: 10.1073/pnas.0913466107

2009

Ring-closing metathesis for the synthesis of heteroaromatics: evaluating routes to pyridines and pyridazines (Journal article)

Donohoe, T. J., Bower, J. F., Basutto, J. A., Fishlock, L. P., Procopiou, P. A., & Callens, C. K. A. (2009). Ring-closing metathesis for the synthesis of heteroaromatics: evaluating routes to pyridines and pyridazines. TETRAHEDRON, 65(44), 8969-8980. doi:10.1016/j.tet.2009.07.076

DOI: 10.1016/j.tet.2009.07.076

Synthesis of substituted pyridines and pyridazines via ring closing metathesis (Journal article)

Donohoe, T. J., Fishlock, L. P., Basutto, J. A., Bower, J. F., Procopiou, P. A., & Thompson, A. L. (2009). Synthesis of substituted pyridines and pyridazines via ring closing metathesis. CHEMICAL COMMUNICATIONS, (21), 3008-3010. doi:10.1039/b904363b

DOI: 10.1039/b904363b

Catalytic Carbonyl Addition through Transfer Hydrogenation: A Departure from Preformed Organometallic Reagents (Journal article)

Bower, J. F., Kim, I. S., Patman, R. L., & Krische, M. J. (2009). Catalytic Carbonyl Addition through Transfer Hydrogenation: A Departure from Preformed Organometallic Reagents. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 48(1), 34-46. doi:10.1002/anie.200802938

DOI: 10.1002/anie.200802938

2008

Kepner-Tregoe Decision Analysis as a Tool To Aid Route Selection. Part 3. Application to a Back-Up Series of Compounds in the PDK Project (Journal article)

Parker, J. S., Bower, J. F., Murray, P. M., Patel, B., & Talavera, P. (2008). Kepner-Tregoe Decision Analysis as a Tool To Aid Route Selection. Part 3. Application to a Back-Up Series of Compounds in the PDK Project. ORGANIC PROCESS RESEARCH & DEVELOPMENT, 12(6), 1060-1077. doi:10.1021/op8000355

DOI: 10.1021/op8000355

Diene Hydroacylation from the Alcohol or Aldehyde Oxidation Level via Ruthenium-Catalyzed C-C Bond-Forming Transfer Hydrogenation: Synthesis of beta,gamma-Unsaturated Ketones (Journal article)

Shibahara, F., Bower, J. F., & Krische, M. J. (2008). Diene Hydroacylation from the Alcohol or Aldehyde Oxidation Level via Ruthenium-Catalyzed C-C Bond-Forming Transfer Hydrogenation: Synthesis of beta,gamma-Unsaturated Ketones. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130(43), 14120-14122. doi:10.1021/ja805356j

DOI: 10.1021/ja805356j

Carbonyl propargylation from the alcohol or aldehyde oxidation level employing 1,3-enynes as surrogates to preformed allenylmetal reagents: A ruthenium-catalyzed C-C bond-forming transfer hydrogenation (Journal article)

Patman, R. L., Williams, V. M., Bower, J. F., & Krische, M. J. (2008). Carbonyl propargylation from the alcohol or aldehyde oxidation level employing 1,3-enynes as surrogates to preformed allenylmetal reagents: A ruthenium-catalyzed C-C bond-forming transfer hydrogenation. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47(28), 5220-5223. doi:10.1002/anie.200801359

DOI: 10.1002/anie.200801359

Ruthenium-catalyzed C-C bond forming transfer hydrogenation: Carbonyl allylation from the alcohol or aldehyde oxidation level employing acyclic 1,3-dienes as surrogates to preformed allyl metal reagents (Journal article)

Shibahara, F., Bower, J. F., & Krische, M. J. (2008). Ruthenium-catalyzed C-C bond forming transfer hydrogenation: Carbonyl allylation from the alcohol or aldehyde oxidation level employing acyclic 1,3-dienes as surrogates to preformed allyl metal reagents. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130(20), 6338-+. doi:10.1021/ja801213x

DOI: 10.1021/ja801213x

Iridium-catalyzed C-C coupling via transfer hydrogenation: Carbonyl addition from the alcohol or aldehyde oxidation level employing 1,3-cyclohexadiene (Journal article)

Bower, J. F., Patman, R. L., & Krische, M. J. (2008). Iridium-catalyzed C-C coupling via transfer hydrogenation: Carbonyl addition from the alcohol or aldehyde oxidation level employing 1,3-cyclohexadiene. ORGANIC LETTERS, 10(5), 1033-1035. doi:10.1021/ol800159w

DOI: 10.1021/ol800159w

Formation of C-C Bonds via Catalytic Hydrogenation and Transfer Hydrogenation: Vinylation, Allylation, and Enolate Addition (Journal article)

Patman, R. L., Bower, J. F., Kim, I. S., & Krische, M. J. (2008). Formation of C-C Bonds via Catalytic Hydrogenation and Transfer Hydrogenation: Vinylation, Allylation, and Enolate Addition. ALDRICHIMICA ACTA, 41(4), 95-104. Retrieved from http://gateway.webofknowledge.com/

2007

Catalytic C-C coupling via transfer hydrogenation: Reverse prenylation, crotylation, and allylation from the alcohol or aldehyde oxidation level (Journal article)

Bower, J. F., Skucas, E., Patman, R. L., & Krische, M. J. (2007). Catalytic C-C coupling via transfer hydrogenation: Reverse prenylation, crotylation, and allylation from the alcohol or aldehyde oxidation level. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 129(49), 15134-+. doi:10.1021/ja077389b

DOI: 10.1021/ja077389b

Cyclic sulfamidates as precursors to alkylidene pyrrolidines and piperidines (Journal article)

Bower, J. F., Szeto, P., & Gallagher, T. (2007). Cyclic sulfamidates as precursors to alkylidene pyrrolidines and piperidines. ORGANIC LETTERS, 9(23), 4909-4912. doi:10.1021/ol7022104

DOI: 10.1021/ol7022104

Carbonyl allylation in the absence of preformed allyl metal reagents: Reverse Prenylation via iridium-catalyzed hydrogenative coupling of dimethylallene (Journal article)

Skucas, E., Bower, J. F., & Krische, M. J. (2007). Carbonyl allylation in the absence of preformed allyl metal reagents: Reverse Prenylation via iridium-catalyzed hydrogenative coupling of dimethylallene. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 129(42), 12678-+. doi:10.1021/ja075971u

DOI: 10.1021/ja075971u

Reactivity of cyclic sulfamidates towards phosphonate-stabilised enolates: synthesis and applications of alpha-phosphono lactams (Journal article)

Bower, J. F., Williams, A. J., Woodward, H. L., Szeto, P., Lawrence, R. M., & Gallagher, T. (2007). Reactivity of cyclic sulfamidates towards phosphonate-stabilised enolates: synthesis and applications of alpha-phosphono lactams. ORGANIC & BIOMOLECULAR CHEMISTRY, 5(16), 2636-2644. doi:10.1039/b706315f

DOI: 10.1039/b706315f

Enantiopure 1,4-benzoxazines via 1,2-cyclic sulfamidates. Synthesis of levofloxacin (Journal article)

Bower, J. F., Szeto, P., & Gallagher, T. (2007). Enantiopure 1,4-benzoxazines via 1,2-cyclic sulfamidates. Synthesis of levofloxacin. ORGANIC LETTERS, 9(17), 3283-3286. doi:10.1021/ol0712475

DOI: 10.1021/ol0712475

Stereospecific construction of substituted piperidines. Synthesis of (-)-paroxetine and (+)-laccarin (Journal article)

Bower, J. F., Riis-Johannessen, T., Szeto, P., Whitehead, A. J., & Gallagher, T. (2007). Stereospecific construction of substituted piperidines. Synthesis of (-)-paroxetine and (+)-laccarin. CHEMICAL COMMUNICATIONS, (7), 728-730. doi:10.1039/b617260a

DOI: 10.1039/b617260a

Cyclic sulfamidates as versatile lactam precursors. An evaluation of synthetic strategies towards (-)-aphanorphine (Journal article)

Bower, J. F., Szeto, P., & Gallagher, T. (2007). Cyclic sulfamidates as versatile lactam precursors. An evaluation of synthetic strategies towards (-)-aphanorphine. ORGANIC & BIOMOLECULAR CHEMISTRY, 5(1), 143-150. doi:10.1039/b614999e

DOI: 10.1039/b614999e

2006

Reactivity of cyclic sulfamidates towards sulfur-stabilised enolates. Stereocontrolled synthesis of functionalised lactams (Journal article)

Bower, J. F., Chakthong, S., Svenda, J., Williams, A. J., Lawrence, R. M., Szeto, P., & Gallagher, T. (2006). Reactivity of cyclic sulfamidates towards sulfur-stabilised enolates. Stereocontrolled synthesis of functionalised lactams. ORGANIC & BIOMOLECULAR CHEMISTRY, 4(10), 1868-1877. doi:10.1039/b601804a

DOI: 10.1039/b601804a

2005

Cyclic sulfamidates as lactam precursors. An efficient asymmetric synthesis of (-)-aphanorphine (Journal article)

Bower, J. F., Szeto, P., & Gallagher, T. (2005). Cyclic sulfamidates as lactam precursors. An efficient asymmetric synthesis of (-)-aphanorphine. CHEMICAL COMMUNICATIONS, (46), 5793-5795. doi:10.1039/b510761j

DOI: 10.1039/b510761j

2004

Cyclic sulfamidates as vehicles for the synthesis of substituted lactams (Journal article)

Bower, J. F., Svenda, J., Williams, A. J., Charmant, J. P. H., Lawrence, R. M., Szeto, P., & Gallagher, T. (2004). Cyclic sulfamidates as vehicles for the synthesis of substituted lactams. ORGANIC LETTERS, 6(25), 4727-4730. doi:10.1021/ol048036+

DOI: 10.1021/ol048036+

2003

Praseodymium complexes of 2,2 '-bipyridine; the crystal and molecular structures of Pr(bipy)(3)(NCS)(3), Pr(bipy)(2)(NO3)(3), Pr(bipy)(2)Cl-3(OH2)center dot EtOH and Pr(bipy)(S2CNEt2)(3) (Journal article)

Bower, J. F., Cotton, S. A., Fawcett, J., Hughes, R. S., & Russell, D. R. (2003). Praseodymium complexes of 2,2 '-bipyridine; the crystal and molecular structures of Pr(bipy)(3)(NCS)(3), Pr(bipy)(2)(NO3)(3), Pr(bipy)(2)Cl-3(OH2)center dot EtOH and Pr(bipy)(S2CNEt2)(3). POLYHEDRON, 22(2), 347-354. doi:10.1016/S0277-5387(02)01359-1

DOI: 10.1016/S0277-5387(02)01359-1