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Dr Ian O'Neil BSc ARCS PhD DIC

Reader Chemistry

    Publications

    2018

    Chemistry of the 8-Nitroguanine DNA Lesion: Reactivity, Labelling and Repair (Journal article)

    Alexander, K. J., McConville, M., Williams, K. R., Luzyanin, K. V., O'Neil, I. A., & Cosstick, R. (2018). Chemistry of the 8-Nitroguanine DNA Lesion: Reactivity, Labelling and Repair. Chemistry: A European Journal, 24(12), 3013-3020. doi:10.1002/chem.201705541

    DOI: 10.1002/chem.201705541

    2017

    SERS and SERRS Detection of the DNA Lesion 8-Nitroguanine: A Self-Labeling Modification (Journal article)

    Dick, S., Bell, S. E. J., Alexander, K. J., O'Neil, I. A., & Cosstick, R. (2017). SERS and SERRS Detection of the DNA Lesion 8-Nitroguanine: A Self-Labeling Modification. Chemistry (Weinheim an der Bergstrasse, Germany), 23(44), 10663-10669. doi:10.1002/chem.201701791

    DOI: 10.1002/chem.201701791

    2016

    Tripodal Tris-N-oxides: Synthesis and Hydrogen Bonding Capabilities (Journal article)

    Nixon, G., Billington, H., Kalindjian, S., Steiner, A., & O'Neil, I. (2016). Tripodal Tris-N-oxides: Synthesis and Hydrogen Bonding Capabilities. Synlett, 27(01), 141-145. doi:10.1055/s-0035-1560533

    DOI: 10.1055/s-0035-1560533

    2014

    The synthesis and structure of chiral enamine N-oxides (Journal article)

    O'Neil, I. A., McConville, M., Zhou, K., Brooke, C., Robertson, C. M., & Berry, N. G. (2014). The synthesis and structure of chiral enamine N-oxides. Chemical Communications, 50(55), 7336-7339. doi:10.1039/c3cc47928e

    DOI: 10.1039/c3cc47928e

    Selective trioxolane based bifunctional molecular linkers for covalent heme surface functionalisation (Journal article)

    McConville, M., Bradley, D. F., Zhou, K., Schiffrin, D., & O'Neil, I. A. (2014). Selective trioxolane based bifunctional molecular linkers for covalent heme surface functionalisation. Chemical Communications, 50(2), 186-188. doi:10.1039/C3CC46041J

    DOI: 10.1039/C3CC46041J

    2012

    Base-pairing preferences, physicochemical properties and mutational behaviour of the DNA lesion 8-nitroguanine. (Journal article)

    Bhamra, I., Compagnone-Post, P., O'Neil, I. A., Iwanejko, L. A., Bates, A. D., & Cosstick, R. (2012). Base-pairing preferences, physicochemical properties and mutational behaviour of the DNA lesion 8-nitroguanine.. Nucleic acids research, 40(21), 11126-11138. doi:10.1093/nar/gks799

    DOI: 10.1093/nar/gks799

    2009

    The Synthesis of functionalised Peptides using alpha-Lithio Quinuclidine N-Oxide (Li-QNO) (Journal article)

    O'Neil, I. A., & Bhamra, I. (2009). The Synthesis of functionalised Peptides using alpha-Lithio Quinuclidine N-Oxide (Li-QNO). Tetrahedron Letters, 50, 3635-3638.

    2008

    A Concise Synthesis of Highly Functionalised 4-Thiosugar Derivatives (Journal article)

    O'Neil, I. A., Southern, J. M., & Kearns, P. (2008). A Concise Synthesis of Highly Functionalised 4-Thiosugar Derivatives. Synlett, 2158-2160.

    Directed Lithiation on the Quinuclidine Ring System: The Synthesis of 1,2 Difunctionalised Quinuclidines (Journal article)

    O'Neil, I. A., Hitchin, J., Bhamra, I., Tapolczay, D. J., & Chorlton, A. P. (2008). Directed Lithiation on the Quinuclidine Ring System: The Synthesis of 1,2 Difunctionalised Quinuclidines. Tetrahedron Letters, 49, 7416-7418.

    2007

    Lithiated Quinuclidine N-Oxide (Patent)

    O'Neil, I. (2007). Lithiated Quinuclidine N-Oxide.

    The diastereoselective synthesis of functionalised spirocyclic lactams and lactones using a Cope elimination/intramolecular nitrone cycloaddition strategy (Journal article)

    Ellis, G. L., O'Neil, I. A., Ramos, V. E., Kalindjian, S. B., Chorlton, A. P., & Tapolczay, D. J. (2007). The diastereoselective synthesis of functionalised spirocyclic lactams and lactones using a Cope elimination/intramolecular nitrone cycloaddition strategy. TETRAHEDRON LETTERS, 48(10), 1687-1690. doi:10.1016/j.tetlet.2007.01.046

    DOI: 10.1016/j.tetlet.2007.01.046

    The synthesis of functionalised chiral bicyclic lactam and lactone N-oxides using a tandem Cope elimination/reverse Cope elimination protocol (Journal article)

    Ellis, G. L., O'Neil, I. A., Ramos, V. E., Cleator, E., Kalindjian, S. B., Chorlton, A. P., & Tapolczay, D. J. (2007). The synthesis of functionalised chiral bicyclic lactam and lactone N-oxides using a tandem Cope elimination/reverse Cope elimination protocol. TETRAHEDRON LETTERS, 48(10), 1683-1686. doi:10.1016/j.tetlet.2007.01.045

    DOI: 10.1016/j.tetlet.2007.01.045

    The diastereoselective synthesis of functionalised spirocyclic lactams and lactones using a Cope elimination/intramolecular nitrone cycloaddition strategy (Journal article)

    Ellis, G. L., O’Neil, I. A., Ramos, V. E., Kalindjian, S. B., Chorlton, A. P., & Tapolczay, D. J. (2007). The diastereoselective synthesis of functionalised spirocyclic lactams and lactones using a Cope elimination/intramolecular nitrone cycloaddition strategy. Tetrahedron Letters, 48(10), 1687-1690. doi:10.1016/j.tetlet.2007.01.046

    DOI: 10.1016/j.tetlet.2007.01.046

    Syntheses of 2'-C-amidoalkyl and 2'-C-cyanoalkyl containing oligodeoxyribonucleotides and assessment of their hybridisation affinity for complementary DNA and RNA (Journal article)

    Brennan, L., Cosstick, R., O'Neil, I. A., & Van Aerschot, A. (2007). Syntheses of 2'-C-amidoalkyl and 2'-C-cyanoalkyl containing oligodeoxyribonucleotides and assessment of their hybridisation affinity for complementary DNA and RNA. Tetrahedron, 63(3), 577-585. doi:10.1016/j.tet.2006.11.024

    DOI: 10.1016/j.tet.2006.11.024

    Synthesis of 2'-C-amidoalkyl and 2'-C-cyanoalkyl containing oligodeoxyribonucleotides and assessment of their hybridisation affinity for complementary DNA and RNA (Journal article)

    Brennan, L., Cosstick, R., O'Neil, I. A., & Van Aerschot, A. (2007). Synthesis of 2'-C-amidoalkyl and 2'-C-cyanoalkyl containing oligodeoxyribonucleotides and assessment of their hybridisation affinity for complementary DNA and RNA. Tetrahedron, 63, 577-585.

    Synthesis of Highly Functionalised Morpholine Amine N-Oxides from Ephedrine and Pseudoephedrine Utilising the Reverse-Cope Elimination (Journal article)

    O'Neil, I. A., & Henry, N. (2007). Synthesis of Highly Functionalised Morpholine Amine N-Oxides from Ephedrine and Pseudoephedrine Utilising the Reverse-Cope Elimination. Tetrahedron Letters, 48, 1691-1694.

    The Synthesis of Functionalised Chiral Bicyclic Lactam and Lactone N-Oxides using a Tandem Cope Elimination/Reverse-Cope Elimination Protocol (Journal article)

    O'Neil, I., Ellis, G. L., Ramos, V. E., Kalindjian, S. B., Chorlton, A. P., & Tapolczay, D. J. (2007). The Synthesis of Functionalised Chiral Bicyclic Lactam and Lactone N-Oxides using a Tandem Cope Elimination/Reverse-Cope Elimination Protocol. Tetrahedron Letters, 48, 1683-1686.

    2006

    Alpha-Lithio-Quinuclidine-N-Oxide (Li-QNO): A New Base for Synthetic Chemistry (Journal article)

    O'Neil, I. A., Bhamra, I., & Gibbons, P. D. (2006). Alpha-Lithio-Quinuclidine-N-Oxide (Li-QNO): A New Base for Synthetic Chemistry. J. Chem. Soc., Chem. Commun, 4545-4547.

    2004

    The diastereoselective synthesis of functionalised isoxazolidines using a Cope elimination/intramolecular nitrone cycloaddition strategy (Journal article)

    O'Neil, I. A., Ramos, V. E., Ellis, G. L., Cleator, E., Chorlton, A. P., Tapolczay, D. J., & Kalindjian, S. B. (2004). The diastereoselective synthesis of functionalised isoxazolidines using a Cope elimination/intramolecular nitrone cycloaddition strategy. Tetrahedron Letters, 45(18), 3659-3661. doi:10.1016/j.tetlet.2004.03.041

    DOI: 10.1016/j.tetlet.2004.03.041

    The synthesis of chiral functionalised morpholine N-oxides using a tandem Cope elimination/reverse-Cope elimination protocol (Journal article)

    O'Neil, I. A., Cleator, E., Elena Ramos, V., Chorlton, A. P., & Tapolczay, D. J. (2004). The synthesis of chiral functionalised morpholine N-oxides using a tandem Cope elimination/reverse-Cope elimination protocol. Tetrahedron Letters, 45(18), 3655-3658. doi:10.1016/j.tetlet.2004.03.040

    DOI: 10.1016/j.tetlet.2004.03.040

    Synthesis and transcription studies on 5'-triphosphates derived from 2'-C-branched-uridines: 2'-homouridine-5'-triphosphate is a substrate for T7 RNA polymerase. (Journal article)

    Pavey, J. B. J., Lawrence, A. J., O'Neil, I. A., Vortler, S., & Cosstick, R. (2004). Synthesis and transcription studies on 5'-triphosphates derived from 2'-C-branched-uridines: 2'-homouridine-5'-triphosphate is a substrate for T7 RNA polymerase.. Organic & biomolecular chemistry, 2(6), 869-875. doi:10.1039/b314348a

    DOI: 10.1039/b314348a

    Synthesis of phosphorothioamidites derived from 3'-thio-3'-deoxythymidine and 3'-thio-2',3'-dideoxycytidine and the automated synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate linkage. (Journal article)

    Sabbagh, G., Fettes, K. J., Gosain, R., O'Neil, I. A., & Cosstick, R. (2004). Synthesis of phosphorothioamidites derived from 3'-thio-3'-deoxythymidine and 3'-thio-2',3'-dideoxycytidine and the automated synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate linkage.. Nucleic acids research, 32(2), 495-501. doi:10.1093/nar/gkh189

    DOI: 10.1093/nar/gkh189

    Organometallics Zn, Cd, Hg, Cu, Ag, Au (Book)

    O'Neil, I. A. (Ed.) (2004). Organometallics Zn, Cd, Hg, Cu, Ag, Au (Vol. 3). Stuttgart: Thieme.

    Preparation and reactions of Iminophosphoranes and their Synthetic Applications in the Aza-Wittig Reaction (Chapter)

    O'Neil, I. A., & Southern, J. M. (2004). Preparation and reactions of Iminophosphoranes and their Synthetic Applications in the Aza-Wittig Reaction. In P. J. Murphy (Ed.), Organophosphorus Reagents (pp. 151-168). Oxford: Oxford University Press.

    2003

    Isoquine and related amodiaquine analogues: A new generation of improved 4-aminoquinoline antimalarials (Journal article)

    O'Neill, P. M., Mukhtar, A., Stocks, P. A., Randle, L. E., Hindley, S., Ward, S. A., . . . Park, B. K. (2003). Isoquine and related amodiaquine analogues: A new generation of improved 4-aminoquinoline antimalarials. JOURNAL OF MEDICINAL CHEMISTRY, 46(23), 4933-4945. doi:10.1021/jm030796n

    DOI: 10.1021/jm030796n

    Kinetics of electron transfer at Pt nanostructured film electrodes (Journal article)

    Horswell, S. L., O'Neil, I. A., & Schiffrin, D. J. (2003). Kinetics of electron transfer at Pt nanostructured film electrodes. JOURNAL OF PHYSICAL CHEMISTRY B, 107(20), 4844-4854. doi:10.1021/jp0340257

    DOI: 10.1021/jp0340257

    Studies on 2'-alpha-C-carboxyalkyl nucleosides and their application to a stereocontrolled nucleobase exchange process. (Journal article)

    Fehring, V., Knights, S., Chan, M. -Y., O'Neil, I. A., & Cosstick, R. (2003). Studies on 2'-alpha-C-carboxyalkyl nucleosides and their application to a stereocontrolled nucleobase exchange process.. Organic & biomolecular chemistry, 1(1), 123-128. doi:10.1039/b208786n

    DOI: 10.1039/b208786n

    a-Lithio quinuclidine N-oxide (Li-QNO): A new base for synthetic chemistry (Journal article)

    O'Neil, I. A., Bhamra, I., & Gibbons, P. D. (n.d.). a-Lithio quinuclidine N-oxide (Li-QNO): A new base for synthetic chemistry. Chem. Commun., (43), 4545-4547. doi:10.1039/b610533e

    DOI: 10.1039/b610533e

    2002

    Probing the effect of a 3'-S-phosphorothiolate link on the conformation of a DNA:RNA hybrid; implications for antisense drug design. (Journal article)

    Beevers, A. P. G., Fettes, K. J., O'Neil, I. A., Roberts, S. M., Arnold, J. R. P., Cosstick, R., & Fisher, J. (2002). Probing the effect of a 3'-S-phosphorothiolate link on the conformation of a DNA:RNA hybrid; implications for antisense drug design.. Chemical communications (Cambridge, England), (14), 1458-1459. doi:10.1039/b203582k

    DOI: 10.1039/b203582k

    2001

    A convenient synthesis of secondary hydroxylamines (Journal article)

    O'Neil, I. A., Cleator, E., & Tapolczay, D. J. (2001). A convenient synthesis of secondary hydroxylamines. Tetrahedron Letters, 42(46), 8247-8249. doi:10.1016/s0040-4039(01)01745-2

    DOI: 10.1016/s0040-4039(01)01745-2

    Novel macrocycles derived from nucleosides. (Journal article)

    Calcerrada-Muñoz, N., O'Neil, I., & Cosstick, R. (2001). Novel macrocycles derived from nucleosides.. Nucleosides, nucleotides & nucleic acids, 20(4-7), 1347-1350. doi:10.1081/ncn-100002552

    DOI: 10.1081/ncn-100002552

    Potential modulated infrared reflectance spectroscopy of Pt-diisocyanide nanostructured electrodes (Journal article)

    Horswell, S. L., O'Neil, I. A., & Schiffrin, D. J. (2001). Potential modulated infrared reflectance spectroscopy of Pt-diisocyanide nanostructured electrodes. JOURNAL OF PHYSICAL CHEMISTRY B, 105(5), 941-947. doi:10.1021/jp002661o

    DOI: 10.1021/jp002661o

    Solid-Phase Synthesis of Oligodeoxynucleotides Containing (Journal article)

    Fettes, K. J., Roberts, S. M., O'Neil, I. A., & Cosstick, R. (2001). Solid-Phase Synthesis of Oligodeoxynucleotides Containing. Nucleosides and Nucleotides, 20, 1351-1354.

    Solid-phase synthesis of oligodeoxynucleotides containing 3'-S-phosphorothiolate linkages (Journal article)

    Fettes, K., Roberts, S. M., O'Neil, I. A., & Cosstick, R. (2001). Solid-phase synthesis of oligodeoxynucleotides containing 3'-S-phosphorothiolate linkages. Nucleosides and Nucleotides, 20, 1351-1354.

    The Stereospecific Addition of Hydroxylamines to alpha,beta-Unsaturated Sulfones, Nitriles and Nitro Compounds (Journal article)

    O'Neil, I. A., Cleator, E., Southern, J. M., Bickley, J., & Tapolczay, D. J. (2001). The Stereospecific Addition of Hydroxylamines to alpha,beta-Unsaturated Sulfones, Nitriles and Nitro Compounds. Tetrahedron Letters, 42, 8251-8254.

    The Synthesis of ?-N-Tosylamino Hydroxylamines via the Ring Opening of N-Tosylaziridines and Their Use in Reverse Cope Cyclizations (Journal article)

    O'Neil, I. A., Woolley, J. C., Southern, J. M., & Hobbs, H. (2001). The Synthesis of ?-N-Tosylamino Hydroxylamines via the Ring Opening of N-Tosylaziridines and Their Use in Reverse Cope Cyclizations. Tetrahedron Letters, 42, 8243-8245.

    2000

    A novel stereo-controlled nucleobase exchange process for the synthesis of 2'-C-branched nucleosides (Journal article)

    Fehring, V., Chan, M. Y., O’Neil, I. A., & Cosstick, R. (2000). A novel stereo-controlled nucleobase exchange process for the synthesis of 2'-C-branched nucleosides. Journal of the Chemical Society, Perkin Transactions 1, (19), 3185-3187. doi:10.1039/b007099h

    DOI: 10.1039/b007099h

    The Synthesis and Functionalisation of Quinuclidine Enamine N-Oxide (Journal article)

    O'Neil, I. A., Lai, J. Y. Q., & Wynn, D. (2000). The Synthesis and Functionalisation of Quinuclidine Enamine N-Oxide. Tetrahedron Letters, 41, 271-274.

    The Synthesis of Chiral Functionalised Piperidines Using a Reverse-Cope Cyclisation: The Effect of Solvent on Diastereoselectivity (Journal article)

    O'Neil, I. A., Cleator, E., Southern, J. M., Hone, N., & Tapolczay, D. J. (2000). The Synthesis of Chiral Functionalised Piperidines Using a Reverse-Cope Cyclisation: The Effect of Solvent on Diastereoselectivity. Synlett, 695-697.

    The Synthesis of Chiral Polyhydroxylated Pyrrolidines Using the Reverse-Cope Cyclisation (Journal article)

    O'Neil, I. A., Cleator, E., Hone, N., & Tapolczay, D. J. (2000). The Synthesis of Chiral Polyhydroxylated Pyrrolidines Using the Reverse-Cope Cyclisation. Synlett, 1408-1410.

    1999

    Alkyl isocyanide-derivatized platinum nanoparticles (Journal article)

    Horswell, S. L., Kiely, C. J., O'Neil, I. A., & Schiffrin, D. J. (1999). Alkyl isocyanide-derivatized platinum nanoparticles. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 121(23), 5573-5574. doi:10.1021/ja984284n

    DOI: 10.1021/ja984284n

    Isolation and Chromatographic Purification of Reaction Products from alpha-Amino Acids, (Chapter)

    O'Neil, I. A. (1999). Isolation and Chromatographic Purification of Reaction Products from alpha-Amino Acids,. In G. C. Barrett (Ed.), Amino Acid Derivatives (pp. 253-259). Oxford: Oxford University Press.

    Quinuclidine N-Oxide: A Potential Replacement for HMPA (Journal article)

    O'Neil, I. A., Lai, J. Y. Q., & Wynn, D. (1999). Quinuclidine N-Oxide: A Potential Replacement for HMPA. J. Chem. Soc., Chem. Commun, 59-60.

    Synthesis and duplex stability of oligodeoxyribonucleotides containing a 2 '-> 5 '-amide linkage (Journal article)

    Chan, M. Y., Fairhurst, R. A., Collingwood, S. P., Fisher, J., Arnold, J. R. P., Cosstick, R., & O'Neil, I. A. (1999). Synthesis and duplex stability of oligodeoxyribonucleotides containing a 2 '-> 5 '-amide linkage. Journal of the Chemical Society-Perkin Transactions 1 (3): 315-320 FEB 7 1999, (3), 315-320.

    1998

    Conformationally defined piperazine bis(N-oxides) bearing amino acid derived side chains (Journal article)

    O'Neil, I. A., Potter, A. J., Southern, J. M., Steiner, A., & Barkley, J. V. (1998). Conformationally defined piperazine bis(N-oxides) bearing amino acid derived side chains. CHEMICAL COMMUNICATIONS, (22), 2511-2512. doi:10.1039/a806901h

    DOI: 10.1039/a806901h

    The synthesis of a novel 2',3'-cyclic phosphate derived from 2'-homouridine (Journal article)

    Pavey, J. B. J., Cosstick, R., & O'Neil, I. A. (1998). The synthesis of a novel 2',3'-cyclic phosphate derived from 2'-homouridine. Tetrahedron Letters, 39(48), 8923-8924. doi:10.1016/s0040-4039(98)01952-2

    DOI: 10.1016/s0040-4039(98)01952-2

    The synthesis of 2'-homouridine, its incorporation into a dinucleoside monophosphate and hydrolytic behaviour of the dimer (Journal article)

    Pavey, J. B. J., Lawrence, A. J., Potter, A. J., Cosstick, R., & O'Neil, I. A. (1998). The synthesis of 2'-homouridine, its incorporation into a dinucleoside monophosphate and hydrolytic behaviour of the dimer. Tetrahedron Letters, 39(38), 6967-6970. doi:10.1016/s0040-4039(98)01478-6

    DOI: 10.1016/s0040-4039(98)01478-6

    DPPE: A Convenient Replacement for Triphenylphosphine in the Staudinger and Mitsunobu Reactions (Journal article)

    O'Neil, I. A., Thompson, S., Murray, C. L., & Kalindjian, S. B. (1998). DPPE: A Convenient Replacement for Triphenylphosphine in the Staudinger and Mitsunobu Reactions. Tetrahedron Letters, 39, 7787-7790.

    Simple Azetidine N-Oxides: Synthesis, Structure and Reactivity (Journal article)

    O'Neil, I. A., & Potter, A. J. (1998). Simple Azetidine N-Oxides: Synthesis, Structure and Reactivity. J. Chem. Soc., Chem. Commun, 1487-1488.

    The Synthesis of Functionalised Beta-Hydroxy Hydroxylamines Via the Ring Opening of Epoxides and Their Use in Reverse Cope Cyclisations (Journal article)

    O'Neil, I. A., & Southern, J. M. (1998). The Synthesis of Functionalised Beta-Hydroxy Hydroxylamines Via the Ring Opening of Epoxides and Their Use in Reverse Cope Cyclisations. Tetrahedron Letters, 39, 9089-9092.

    1997

    A New Tin Mediated Pummerer Synthesis of Vinyl Stannanes (Journal article)

    O'Neil, I., & Southern, J. (1997). A New Tin Mediated Pummerer Synthesis of Vinyl Stannanes. Synlett, 1997(10), 1165-1166. doi:10.1055/s-1997-987

    DOI: 10.1055/s-1997-987

    The highly stereoselective formation of pipecolic acid N-oxide and related derivatives (Journal article)

    O'Neil, I. A., & Potter, A. J. (1997). The highly stereoselective formation of pipecolic acid N-oxide and related derivatives. Tetrahedron Letters, 38(32), 5731-5734. doi:10.1016/s0040-4039(97)01258-6

    DOI: 10.1016/s0040-4039(97)01258-6

    Homochiral Amine Oxides in the Enantioselective Reduction of Ketones (Journal article)

    O'Neil, I., Turner, C., & Kalindjian, S. (1997). Homochiral Amine Oxides in the Enantioselective Reduction of Ketones. Synlett, 1997(7), 777-780. doi:10.1055/s-1997-5770

    DOI: 10.1055/s-1997-5770

    The synthesis of a novel benzodiazocine via an intramolecular Staudinger/aza-Wittig cyclization (Journal article)

    O'Neil, I. A., Murray, C. L., Potter, A. J., & Kalindjian, S. B. (1997). The synthesis of a novel benzodiazocine via an intramolecular Staudinger/aza-Wittig cyclization. Tetrahedron Letters, 38(20), 3609-3610. doi:10.1016/s0040-4039(97)00680-1

    DOI: 10.1016/s0040-4039(97)00680-1

    "99Tcm-L,L-Ethylenedicysteine (EC) for ERPF: A Suitable Alternative (Journal article)

    Noonan, E. C., Stringer, R., Maltby, P., Aldersey-Williams, B., O'Neil, I. A., & Turner, C. D. (1997). "99Tcm-L,L-Ethylenedicysteine (EC) for ERPF: A Suitable Alternative. Nuclear Medicine Communications, 18, 300-303.

    Synthesis, structure and reactions of uridine 2'-C,3'-O-gamma-butyrolactone: versatile intermediate for the synthesis of 2'-C-branched nucleosides (Journal article)

    Lawrence, A. J., Pavey, J. B. J., Chan, M. Y., Fairhurst, R. A., Collingwood, S. P., Fisher, J., . . . ONeil, I. A. (1997). Synthesis, structure and reactions of uridine 2'-C,3'-O-gamma-butyrolactone: versatile intermediate for the synthesis of 2'-C-branched nucleosides. Journal of the Chemical Society-Perkin Transactions 1, (18), 2761-2767.

    The Synthesis of Functionalized Pyrrolo-[2,1-c][1,4]-Benzodiazepines (Journal article)

    O'Neil, I., Murray, C., Hunter, R., Kalindjian, S., & Jenkins, T. (n.d.). The Synthesis of Functionalized Pyrrolo-[2,1-c][1,4]-Benzodiazepines. Synlett, 1(01), 75-78. doi:10.1055/s-1997-693

    DOI: 10.1055/s-1997-693

    The synthesis of 2'-C-functionalised nucleosides for incorporation into catalytic RNA (Journal article)

    Lawrence, A. J., Pavey, J. B. J., ONeil, I. A., & Cosstick, R. (1997). The synthesis of 2'-C-functionalised nucleosides for incorporation into catalytic RNA. Nucleosides and Nucleotides, 16(7-9), 497-1501.

    1996

    Synthesis and Properties of 2‘-Deoxy-2‘-a-C-branched Nucleosides and Nucleotides (Journal article)

    Lawrence, A. J., Pavey, J. B. J., Cosstick, R., & O'Neil, I. A. (1996). Synthesis and Properties of 2‘-Deoxy-2‘-a-C-branched Nucleosides and Nucleotides. The Journal of Organic Chemistry, 61(26), 9213-9222. doi:10.1021/jo9614607

    DOI: 10.1021/jo9614607

    The Total Synthesis of Trichoviridin (Journal article)

    Baldwin, J. E., Adlington, R. M., O'Neil, I. A., Russell, A. T., & Smith, M. L. (1996). The Total Synthesis of Trichoviridin. J. Chem. Soc., Chem. Commun, 41-42.

    1995

    A New Approach to the Synthesis of 4-Thio-1,2-Dideoxyribose (Journal article)

    O’Neil, I. A., Hamilton, K. M., & Miller, J. A. (1995). A New Approach to the Synthesis of 4-Thio-1,2-Dideoxyribose. Synlett, 1995(10), 1053-1054. doi:10.1055/s-1995-5165

    DOI: 10.1055/s-1995-5165

    Homochiral Proline N-Oxides as Conformational Constraints in Peptide Like Molecules (Journal article)

    O’Neil, I. A., Miller, N. D., Barkley, J. V., Low, C. M. R., & Kalindjian, S. B. (1995). Homochiral Proline N-Oxides as Conformational Constraints in Peptide Like Molecules. Synlett, 1995(06), 619-621. doi:10.1055/s-1995-5026

    DOI: 10.1055/s-1995-5026

    The Synthesis of Proline Derived Homochiral Amine Oxides (Journal article)

    O’Neil, I. A., Miller, N. D., Barkley, J. V., Low, C. M. R., & Kalindjian, S. B. (1995). The Synthesis of Proline Derived Homochiral Amine Oxides. Synlett, 1995(06), 617-618. doi:10.1055/s-1995-5027

    DOI: 10.1055/s-1995-5027

    A Convenient Synthesis of 5-Substituted-2,3-Dihydrothiophenes (Journal article)

    O’Neil, I. A., Hamilton, K. M., Miller, J. A., & Young, R. J. (1995). A Convenient Synthesis of 5-Substituted-2,3-Dihydrothiophenes. Synlett, 1995(02), 151-152. doi:10.1055/s-1995-4895

    DOI: 10.1055/s-1995-4895

    Synthesis of Functionalized 2'-C-Branched Nucleosides via their gamma-Butyrolactones (Journal article)

    Lawrence, A. J., Pavey, J. B. J., O'Neil, I. A., & Cosstick, R. (1995). Synthesis of Functionalized 2'-C-Branched Nucleosides via their gamma-Butyrolactones. Tetrahedron Letters, 36(35), 6341-6343.

    The Synthesis of Isocyanides (Chapter)

    O'Neil, I. A. (1995). The Synthesis of Isocyanides. In G. Pattenden, A. Katritzky, O. Meth Cohn, & C. W. Rees (Eds.), Comprehensive Functional Group Transformations (Vol. 3, pp. 693-726). Oxford: Pergamon Press.

    1993

    The Novel Use of Proline Derived Amine Oxides in Controlling Amide Conformation (Journal article)

    O'Neil, I. A., Miller, N. D., Peake, J., Barkley, J. V., Low, C. M. R., & Kalindjian, S. B. (1993). The Novel Use of Proline Derived Amine Oxides in Controlling Amide Conformation. Synlett, 1993(07), 515-518. doi:10.1055/s-1993-22513

    DOI: 10.1055/s-1993-22513

    1992

    A Novel Method for the Coupling of Nucleoside Bases with Tetramethylene Sulphoxide (Journal article)

    O'Neil, I., & Hamilton, K. (n.d.). A Novel Method for the Coupling of Nucleoside Bases with Tetramethylene Sulphoxide. Synlett, 1992(10), 791-792. doi:10.1055/s-1992-21491

    DOI: 10.1055/s-1992-21491

    1991

    Isonitrin A: Revision of the Structure and Total Synthesis in Racemic Form (Journal article)

    Baldwin, J. E., O'Neil, I. A., & Russell, A. T. (1991). Isonitrin A: Revision of the Structure and Total Synthesis in Racemic Form. Synlett, 1991(08), 551-552. doi:10.1055/s-1991-20792

    DOI: 10.1055/s-1991-20792

    Reverse Phase Flash Chromatography: A Convenient Method for the Large Scale Separation of Polar Compounds (Journal article)

    O'Neil, I. A. (1991). Reverse Phase Flash Chromatography: A Convenient Method for the Large Scale Separation of Polar Compounds. Synlett, 1991(09), 661-662. doi:10.1055/s-1991-20833

    DOI: 10.1055/s-1991-20833

    1990

    A new and mild procedure for the preparation of vinyl formamides from thiooximes (Journal article)

    Baldwin, J. E., Aldous, D. J., & O'Neil, I. A. (1990). A new and mild procedure for the preparation of vinyl formamides from thiooximes. Tetrahedron Letters, 31(14), 2051-2054. doi:10.1016/s0040-4039(00)88913-3

    DOI: 10.1016/s0040-4039(00)88913-3

    The preparation of epoxy isonitriles (isocyanooxiranes) (Journal article)

    Baldwin, J. E., & O'Neil, I. A. (1990). The preparation of epoxy isonitriles (isocyanooxiranes). Tetrahedron Letters, 31(14), 2047-2050. doi:10.1016/s0040-4039(00)88912-1

    DOI: 10.1016/s0040-4039(00)88912-1

    Trifluoromethanesulfonic Anhydride, a Superior Reagent for the Conversion of Formamides to Isonitriles (Journal article)

    Baldwin, J. E., & O'Neil, I. A. (1990). Trifluoromethanesulfonic Anhydride, a Superior Reagent for the Conversion of Formamides to Isonitriles. Synlett, 1990(10), 603-604. doi:10.1055/s-1990-21181

    DOI: 10.1055/s-1990-21181

    1989

    The Ring Opening of Aziridine-2-Ester Carboxylates with Organometallic Reagents (Journal article)

    Baldwin, J. E., Adlington, R. M., O'Neil, I. A., Schofield, C. J., Spivey, A. C., & Sweeney, J. B. (1989). The Ring Opening of Aziridine-2-Ester Carboxylates with Organometallic Reagents. J. Chem. Soc., Chem. Commun, (23), 1852-1853.

    The Total Synthesis of Isonitrin B (Deoxytrichoviridin)" (Journal article)

    Baldwin, J. E., Aldous, D. J., Chan, C., Harwood, L. M., O'Neil, I. A., & Peach, J. M. (1989). The Total Synthesis of Isonitrin B (Deoxytrichoviridin)". Synlett, 9-14.

    1988

    Tristrimethylsilylation of phenol and related reactions (Journal article)

    Barrett, A. G. M., & O'Neil, I. A. (1988). Tristrimethylsilylation of phenol and related reactions. The Journal of Organic Chemistry, 53(8), 1815-1817. doi:10.1021/jo00243a044

    DOI: 10.1021/jo00243a044

    Reactions of Glycidyl Radical Equivalent with 2-Functionalized Allyl Stannanes (Journal article)

    Baldwin, J. E., Adlington, R. M., Lowe, C., O'Neil, I. A., Sanders, G. L., Schofield, C. J., & Sweeney, J. B. (1988). Reactions of Glycidyl Radical Equivalent with 2-Functionalized Allyl Stannanes. J. Chem. Soc., Chem. Commun, (15), 1030-1031.

    1986

    Ultrasonic formation and reactions of sodium phenylselenide (Journal article)

    Ley, S. V., O'Neil, L. A., & Low, C. M. R. (1986). Ultrasonic formation and reactions of sodium phenylselenide. Tetrahedron, 42(19), 5363-5368. doi:10.1016/s0040-4020(01)82086-x

    DOI: 10.1016/s0040-4020(01)82086-x

    1984

    Preparation and reactions of 4-(trimethylsilyl)indole (Journal article)

    Dauzonne, D., O'Neil, I. A., & Renaud, A. (1984). Preparation and reactions of 4-(trimethylsilyl)indole. The Journal of Organic Chemistry, 49(23), 4409-4415. doi:10.1021/jo00197a016

    DOI: 10.1021/jo00197a016