2024
Diagnostic markers of acute encephalitis syndrome and COVID-associated multisystem inflammatory syndrome in children from Southern India. (Journal article)
Damodar, T., Dunai, C., Prabhu, N., Jose, M., Akhila, L., Kinhal, U. V., . . . Mani, R. S. (2024). Diagnostic markers of acute encephalitis syndrome and COVID-associated multisystem inflammatory syndrome in children from Southern India.. Journal of medical virology, 96(5), e29666. doi:10.1002/jmv.29666DOI: 10.1002/jmv.29666
Michael, B. D., Dunai, C., Needham, E. J., Tharmaratnam, K., Williams, R., Huang, Y., . . . Menon, D. K. (2024). Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.. Nature communications, 15(1), 2918. doi:10.1038/s41467-024-47320-6DOI: 10.1038/s41467-024-47320-6
Lower than expected? Establishing a PSA density threshold (Journal article)
Dawson, J., Yassaie, O., Tharmaratnam, K., Garcia-Finana, M., Probert, C., Lazarowicz, H. P., & Cornford, P. A. (2024). Lower than expected? Establishing a PSA density threshold. European Urology, 85, S1689. doi:10.1016/s0302-2838(24)01294-6DOI: 10.1016/s0302-2838(24)01294-6
Cognitive domains affected post-COVID-19; a systematic review and meta-analysis. (Journal article)
Fanshawe, J. B., Sargent, B. F., Badenoch, J. B., Saini, A., Watson, C. J., Pokrovskaya, A., . . . Leek, C. E. (2024). Cognitive domains affected post-COVID-19; a systematic review and meta-analysis.. European journal of neurology, e16181. doi:10.1111/ene.16181DOI: 10.1111/ene.16181
2023
Michael, B. D., Dunai, C., Needham, E. J., Tharmaratnam, K., Williams, R., Huang, Y., . . . Menon, D. K. (2023). Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.. Nature communications, 14(1), 8487. doi:10.1038/s41467-023-42320-4DOI: 10.1038/s41467-023-42320-4
Defres, S., Tharmaratnam, K., Michael, B. D., Ellul, M., Davies, N. W. S., Easton, A., . . . Solomon, T. (2023). Clinical predictors of encephalitis in UK adults-A multi-centre prospective observational cohort study.. PloS one, 18(8), e0282645. doi:10.1371/journal.pone.0282645DOI: 10.1371/journal.pone.0282645
Scientific Business Abstracts (Journal article)
Siew, K., Patel, V., Zimmermann, J., Vaughan, M., Cheshire, C., Kubik, A., . . . Leek, C. (n.d.). Scientific Business Abstracts. QJM: An International Journal of Medicine. doi:10.1093/qjmed/hcad072DOI: 10.1093/qjmed/hcad072
Burnside, G., Cheyne, C. P., Leeming, G., Humann, M., Darby, A., Green, M. A., . . . Buchan, I. E. (2023). COVID-19 risk-mitigation in reopening mass cultural events: population-based observational study for the UK Events Research Programme in Liverpool City Region. Journal of the Royal Society of Medicine. doi:10.1177/01410768231182389DOI: 10.1177/01410768231182389
A Novel Filter and Embedded Feature Selection Methods applied to High Dimensional Metabolomics Data in Enhancing Colorectal Cancer Classification (Preprint)
DOI: 10.21203/rs.3.rs-2905357/v1
2022
Phase I/II Clinical Trials of Donor-Derived Purified Regulatory T Cells for the Treatment of Steroid-Refractory Chronic Graft Versus Host Disease (Conference Paper)
Soares, M. V., Gomez, V. E., Azevedo, R. I., Pereira, P. N. G., Velazquez, T. C., Garcia-Calderon, C. B., . . . Lacerda, J. F. (2022). Phase I/II Clinical Trials of Donor-Derived Purified Regulatory T Cells for the Treatment of Steroid-Refractory Chronic Graft Versus Host Disease. In BLOOD Vol. 140. doi:10.1182/blood-2022-163394DOI: 10.1182/blood-2022-163394
Wood, G. K., Babar, R., Ellul, M. A., Thomas, R. H., Van Den Tooren, H., Easton, A., . . . Michael, B. D. (2022). Acute seizure risk in patients with encephalitis: development and validation of clinical prediction models from two independent prospective multicentre cohorts. BMJ Neurology Open, 4(2), e000323. doi:10.1136/bmjno-2022-000323DOI: 10.1136/bmjno-2022-000323
Smith, E. M. D., Tharmaratnam, K., Al-Abadi, E., Armon, K., Bailey, K., Brennan, M., . . . Beresford, M. W. (n.d.). Attainment of low disease activity and remission targets reduces the risk of severe flare and new damage in childhood lupus. Rheumatology. doi:10.1093/rheumatology/keab915DOI: 10.1093/rheumatology/keab915
2021
THE UTILITY OF ESTABLISHED PROGNOSTIC SCORES IN COVID-19 HOSPITAL ADMISSIONS: A COLLABORATIVE TRAINEE-LED, MULTI-CENTRE PROSPECTIVE EVALUATION OF CURB-65, NEWS2, AND QSOFA (Conference Paper)
Frost, F., Bradley, P., Tharmaratnam, K., & Wootton, D. (2021). THE UTILITY OF ESTABLISHED PROGNOSTIC SCORES IN COVID-19 HOSPITAL ADMISSIONS: A COLLABORATIVE TRAINEE-LED, MULTI-CENTRE PROSPECTIVE EVALUATION OF CURB-65, NEWS2, AND QSOFA. In THORAX Vol. 76 (pp. A57-A58). doi:10.1136/thorax-2020-BTSabstracts.100DOI: 10.1136/thorax-2020-BTSabstracts.100
2020
Bradley, P., Frost, F., Tharmaratnam, K., & Wootton, D. G. (2020). The utility of established prognostic scores in COVID-19 hospital admissions: a multi-centre prospective evaluation of CURB-65, NEWS2, and qSOFA. BMJ Open Respiratory Research, 7(1). doi:10.1101/2020.07.15.20154815DOI: 10.1101/2020.07.15.20154815
Bradley, P., Frost, F., Tharmaratnam, K., & Wootton, D. G. (2020). Utility of established prognostic scores in COVID-19 hospital admissions: multicentre prospective evaluation of CURB-65, NEWS2 and qSOFA. BMJ OPEN RESPIRATORY RESEARCH, 7(1). doi:10.1136/bmjresp-2020-000729DOI: 10.1136/bmjresp-2020-000729
Harris, L., Griem, J., Gummery, A., Marsh, L., Defres, S., Bhojak, M., . . . ENCEPH UK study group. (2020). Neuropsychological and psychiatric outcomes in encephalitis: A multi-centre case-control study.. PloS one, 15(3), e0230436. doi:10.1371/journal.pone.0230436DOI: 10.1371/journal.pone.0230436
2018
Cancer risk and survival in <i>path</i>_<i>MMR</i> carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database (Journal article)
Moller, P., Seppala, T. T., Bernstein, I., Holinski-Feder, E., Sala, P., Evans, D. G., . . . Capella, G. (2018). Cancer risk and survival in <i>path</i>_<i>MMR</i> carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database. GUT, 67(7), 1306-1316. doi:10.1136/gutjnl-2017-314057DOI: 10.1136/gutjnl-2017-314057
Identification of predicted individual treatment effects in randomized clinical trials (Journal article)
Lamont, A., Lyons, M. D., Jaki, T., Stuart, E., Feaster, D. J., Tharmaratnam, K., . . . Van Horn, M. L. (2018). Identification of predicted individual treatment effects in randomized clinical trials. STATISTICAL METHODS IN MEDICAL RESEARCH, 27(1), 142-157. doi:10.1177/0962280215623981DOI: 10.1177/0962280215623981
2017
Seppala, T., Pylvanainen, K., Evans, D. G., Jarvinen, H., Renkonen-Sinisalo, L., Bernstein, I., . . . Moller, P. (2017). Colorectal cancer incidence in <i>path_MLH1</i> carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report. HEREDITARY CANCER IN CLINICAL PRACTICE, 15. doi:10.1186/s13053-017-0078-5DOI: 10.1186/s13053-017-0078-5
Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database (Journal article)
Moller, P., Seppala, T., Bernstein, I., Holinski-Feder, E., Sala, P., Evans, D. G., . . . Capella, G. (2017). Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database. GUT, 66(9), 1657-1664. doi:10.1136/gutjnl-2016-311403DOI: 10.1136/gutjnl-2016-311403
Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database (Journal article)
Moller, P., Seppala, T., Bernstein, I., Holinski-Feder, E., Sala, P., Evans, D. G., . . . Moslein, G. (2017). Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database. GUT, 66(3), 464-472. doi:10.1136/gutjnl-2015-309675DOI: 10.1136/gutjnl-2015-309675
Point and interval estimation for predicting individual patients treatment effect based on randomized clinical trial data (Conference Paper)
Tharmaratnam, K., & Jaki, T. (2017). Point and interval estimation for predicting individual patients treatment effect based on randomized clinical trial data. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
2016
Tilting the lasso by knowledge-based post-processing (Journal article)
Tharmaratnam, K., Sperrin, M., Jaki, T., Reppe, S., & Frigessi, A. (2016). Tilting the lasso by knowledge-based post-processing. BMC BIOINFORMATICS, 17. doi:10.1186/s12859-016-1210-7DOI: 10.1186/s12859-016-1210-7
Intensive breast screening in <i>BRCA2</i> mutation carriers is associated with reduced breast cancer specific and all cause mortality (Journal article)
Evans, D. G., Harkness, E. F., Howell, A., Wilson, M., Hurley, E., Holmen, M. M., . . . Moller, P. (2016). Intensive breast screening in <i>BRCA2</i> mutation carriers is associated with reduced breast cancer specific and all cause mortality. HEREDITARY CANCER IN CLINICAL PRACTICE, 14. doi:10.1186/s13053-016-0048-3DOI: 10.1186/s13053-016-0048-3
2015
Tumour characteristics and survival in familial breast cancer prospectively diagnosed by annual mammography (Journal article)
Moller, P., Tharmaratnam, K., Howell, A., Stavrinos, P., Sampson, S., Wallace, A., . . . Evans, D. G. (2015). Tumour characteristics and survival in familial breast cancer prospectively diagnosed by annual mammography. BREAST CANCER RESEARCH AND TREATMENT, 152(1), 87-94. doi:10.1007/s10549-015-3448-6DOI: 10.1007/s10549-015-3448-6
Ten modifiers of <i>BRCA1</i> penetrance validated in a Norwegian series (Journal article)
Heramb, C., Ekstrom, P. O., Tharmaratnam, K., Hovig, E., Moller, P., & Maehle, L. (2015). Ten modifiers of <i>BRCA1</i> penetrance validated in a Norwegian series. HEREDITARY CANCER IN CLINICAL PRACTICE, 13. doi:10.1186/s13053-015-0035-0DOI: 10.1186/s13053-015-0035-0
Regression (Chapter)
Glad, I. K., & Tharmaratnam, K. (2015). Regression. In Encyclopedia of Applied and Computational Mathematics (pp. 1225-1233). Springer Berlin Heidelberg. doi:10.1007/978-3-540-70529-1_420DOI: 10.1007/978-3-540-70529-1_420
2014
MRI screening of women with hereditary predisposition to breast cancer: diagnostic performance and survival analysis (Journal article)
Tharmaratnam, K., Hagen, A. I., & Moller, P. (2014). MRI screening of women with hereditary predisposition to breast cancer: diagnostic performance and survival analysis. BREAST CANCER RESEARCH AND TREATMENT, 148(3), 687-688. doi:10.1007/s10549-014-3178-1DOI: 10.1007/s10549-014-3178-1
2013
Monotone splines lasso (Journal article)
Bergersen, L. C., Tharmaratnam, K., & Glad, I. K. (2014). Monotone splines lasso. COMPUTATIONAL STATISTICS & DATA ANALYSIS, 77, 336-351. doi:10.1016/j.csda.2014.03.013DOI: 10.1016/j.csda.2014.03.013
A comparison of robust versions of the AIC based on M-, S- and MM-estimators (Journal article)
Tharmaratnam, K., & Claeskens, G. (2013). A comparison of robust versions of the AIC based on M-, S- and MM-estimators. Statistics, 47(1), 216-235. doi:10.1080/02331888.2011.568120DOI: 10.1080/02331888.2011.568120
2011
S-Estimation and a Robust Conditional Akaike Information Criterion for Linear Mixed Models (Journal article)
Tharmaratnam, K., & Claeskens, G. (2011). S-Estimation and a Robust Conditional Akaike Information Criterion for Linear Mixed Models.
2010
S-Estimation for Penalized Regression Splines (Journal article)
Tharmaratnam, K., Claeskens, G., Croux, C., & Salibián-Barrera, M. (2010). S-Estimation for Penalized Regression Splines. Journal of Computational and Graphical Statistics, 19(3), 609-625. doi:10.1198/jcgs.2010.08149DOI: 10.1198/jcgs.2010.08149
