Professor Helen Sharp B.Sc. (HONS) M.Phil. Ph.D. D.Clin.Psy.
Professor of Perinatal and Clinical Child Psychology Primary Care & Mental Health
- Work email Hmsharp@liverpool.ac.uk
Publications
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2022
Synergy between callous-unemotional traits and aggression in preschool children: Cross-informant and cross-cultural replication in the UK Wirral Child Health and Development Study, and the Colombian La Sabana Parent-Child Study. (Journal article)
Obando, D., Hill, J., Sharp, H., Pickles, A., Fisher, L., & Wright, N. (2022). Synergy between callous-unemotional traits and aggression in preschool children: Cross-informant and cross-cultural replication in the UK Wirral Child Health and Development Study, and the Colombian La Sabana Parent-Child Study. DEVELOPMENT AND PSYCHOPATHOLOGY, 34(3), 1079-1087. doi:10.1017/S0954579420002114A Comparison of Non-verbal Maternal Care of Male and Female Infants in India and the United Kingdom: The Parent-Infant Caregiving Touch Scale in Two Cultures (Journal article)
Hodsoll, J., Pickles, A., Bozicevic, L., Supraja, T. A., Hill, J., Chandra, P. S., & Sharp, H. (2022). A Comparison of Non-verbal Maternal Care of Male and Female Infants in India and the United Kingdom: The Parent-Infant Caregiving Touch Scale in Two Cultures. FRONTIERS IN PSYCHOLOGY, 13. doi:10.3389/fpsyg.2022.8526182021
Anxiety and depressive symptoms in pregnancy predict low birth weight differentially in male and female infants-findings from an urban pregnancy cohort in India (Journal article)
Chandra, P. S., Bajaj, A., Desai, G., Satyanarayana, V. A., Sharp, H. M., Ganjekar, S., . . . Kandavel, T. (2021). Anxiety and depressive symptoms in pregnancy predict low birth weight differentially in male and female infants-findings from an urban pregnancy cohort in India. SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY, 56(12), 2263-2274. doi:10.1007/s00127-021-02106-9Breast may not always be best: moderation of effects of postnatal depression by breastfeeding and infant sex (Journal article)
Braithwaite, E. C., Sharp, H., Pickles, A., Hill, J., & Wright, N. (2021). Breast may not always be best: moderation of effects of postnatal depression by breastfeeding and infant sex. BIOLOGY OF SEX DIFFERENCES, 12(1). doi:10.1186/s13293-021-00403-1Emotion Recognition Performance in Children with Callous Unemotional Traits is Modulated by Co-occurring Autistic Traits (Journal article)
Bedford, R., Leno, V. C., Wright, N., Bluett-Duncan, M., Smith, T. J., Anzures, G., . . . Hill, J. (2021). Emotion Recognition Performance in Children with Callous Unemotional Traits is Modulated by Co-occurring Autistic Traits. JOURNAL OF CLINICAL CHILD AND ADOLESCENT PSYCHOLOGY, 50(6), 811-827. doi:10.1080/15374416.2020.1833338Do stress and anxiety in early pregnancy affect the progress of labor: Evidence from the Wirral Child Health and Development Study (Journal article)
Slade, P., Sheen, K., Weeks, A., Wray, S., De Pascalis, L., Lunt, K., . . . Sharp, H. (2021). Do stress and anxiety in early pregnancy affect the progress of labor: Evidence from the Wirral Child Health and Development Study. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 100(7), 1288-1296. doi:10.1111/aogs.14063A systematic review of the association between perinatal depression and cognitive development in infancy in low and middle-income countries (Journal article)
Bluett-Duncan, M., Kishore, M. T., Patil, D. M., Satyanarayana, V. A., & Sharp, H. (2021). A systematic review of the association between perinatal depression and cognitive development in infancy in low and middle-income countries. PLOS ONE, 16(6). doi:10.1371/journal.pone.0253790The feasibility of using videos to assess maternal sensitivity in low income urban settings in India - The researcher's perspective (Journal article)
Holla, C., Bozicevic, L., Sharp, H., & Chandra, P. S. (2021). The feasibility of using videos to assess maternal sensitivity in low income urban settings in India - The researcher's perspective. ASIAN JOURNAL OF PSYCHIATRY, 61. doi:10.1016/j.ajp.2021.102672A psychometric and validity study of callous-unemotional traits in 2.5 year old children (Journal article)
Wright, N., Pickles, A., Sharp, H., & Hill, J. (2021). A psychometric and validity study of callous-unemotional traits in 2.5 year old children. SCIENTIFIC REPORTS, 11(1). doi:10.1038/s41598-021-87416-3Commentary response: Addressing the scientific as well as the social‐inequalities questions ‐ Response to the commentary of Newlove‐Delgado (2021) (Journal article)
Wright, N., Hill, J., Sharp, H., & Pickles, A. (2021). Commentary response: Addressing the scientific as well as the social‐inequalities questions ‐ Response to the commentary of Newlove‐Delgado (2021). JCPP Advances, 1(1). doi:10.1111/jcv2.12015Interplay between long‐term vulnerability and new risk: Young adolescent and maternal mental health immediately before and during the COVID‐19 pandemic (Journal article)
Wright, N., Hill, J., Sharp, H., & Pickles, A. (2021). Interplay between long-term vulnerability and new risk: Young adolescent and maternal mental health immediately before and during the COVID-19 pandemic.. JCPP advances, 1(1), e12008. doi:10.1111/jcv2.120082020
Sex differences in foetal origins of child emotional symptoms: a test of evolutionary hypotheses in a large, general population cohort (Journal article)
Braithwaite, E. C., Pickles, A., Wright, N., Sharp, H., & Hill, J. (2020). Sex differences in foetal origins of child emotional symptoms: a test of evolutionary hypotheses in a large, general population cohort. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY, 61(11), 1194-1202. doi:10.1111/jcpp.13229Impact of COVID-19 on Young Adolescent Mental Health: Comparison of Depression, Anxiety and Behaviour Problems in 12 Year Olds Immediately Before and During the Pandemic in a UK Birth Cohort (Preprint)
2019
Sex-dependent associations between maternal prenatal cortisol and child callous-unemotional traits: Findings from the Wirral Child Health and Development Study (Journal article)
Wright, N., Pickles, A., Braithwaite, E. C., Sharp, H., & Hill, J. (2019). Sex-dependent associations between maternal prenatal cortisol and child callous-unemotional traits: Findings from the Wirral Child Health and Development Study. PSYCHONEUROENDOCRINOLOGY, 109. doi:10.1016/j.psyneuen.2019.104409Mapping early environment using communication deviance: A longitudinal study of maternal sensitivity toward 6-month-old children (Journal article)
de Sousa, P., Sellwood, W., Fien, K., Sharp, H., Pickles, A., Hill, J., . . . Bentall, R. P. (2019). Mapping early environment using communication deviance: A longitudinal study of maternal sensitivity toward 6-month-old children. DEVELOPMENT AND PSYCHOPATHOLOGY, 31(4), 1501-1511. doi:10.1017/S0954579418001189Mismatched Prenatal and Postnatal Maternal Depressive Symptoms and Child Behaviours: A Sex-Dependent Role for NR3C1 DNA Methylation in the Wirral Child Health and Development Study (Journal article)
Hill, J., Pickles, A., Wright, N., Quinn, J. P., Murgatroyd, C., & Sharp, H. (2019). Mismatched Prenatal and Postnatal Maternal Depressive Symptoms and Child Behaviours: A Sex-Dependent Role for NR3C1 DNA Methylation in the Wirral Child Health and Development Study. CELLS, 8(9). doi:10.3390/cells8090943Distinct chromatin structures at the monoamine oxidase-A promoter correlate with allele-specific expression in SH-SY5Y cells (Journal article)
Manca, M., Pessoa, V., Myers, P., Pickles, A., Hill, J., Sharp, H., . . . Quinn, J. P. (2019). Distinct chromatin structures at the monoamine oxidase-A promoter correlate with allele-specific expression in SH-SY5Y cells. GENES BRAIN AND BEHAVIOR, 18(6). doi:10.1111/gbb.12483How does perinatal maternal mental health explain early social inequalities in child behavioural and emotional problems? Findings from the Wirral Child Health and Development Study. (Journal article)
Rutherford, C., Sharp, H., Hill, J., Pickles, A., & Taylor-Robinson, D. (2019). How does perinatal maternal mental health explain early social inequalities in child behavioural and emotional problems? Findings from the Wirral Child Health and Development Study.. PloS one, 14(5), e0217342. doi:10.1371/journal.pone.0217342Predictions of children's emotionality from evolutionary and epigenetic hypotheses (Journal article)
Hill, J., Pickles, A., Wright, N., Braithwaite, E., & Sharp, H. (2019). Predictions of children's emotionality from evolutionary and epigenetic hypotheses. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-39513-7Callous-unemotional traits, low cortisol reactivity and physical aggression in children: findings from the Wirral Child Health and Development Study (Journal article)
Wright, N., Hill, J., Pickles, A., & Sharp, H. (2019). Callous-unemotional traits, low cortisol reactivity and physical aggression in children: findings from the Wirral Child Health and Development Study. TRANSLATIONAL PSYCHIATRY, 9. doi:10.1038/s41398-019-0406-92018
Regulatory characterisation of the schizophrenia-associated CACNA1C proximal promoter and the potential role for the transcription factor EZH2 in schizophrenia aetiology (Journal article)
Billingsley, K. J., Manca, M., Gianfrancesco, O., Collier, D., Sharp, H. M., Bubb, V. J., & Quinn, J. (2018). Regulatory characterisation of the schizophrenia-associated CACNA1C proximal promoter and the potential role for the transcription factor EZH2 in schizophrenia aetiology. Schizophrenia Research, 199, 168-175. doi:10.1016/j.schres.2018.02.036Associations between maternal prenatal cortisol and fetal growth are specific to infant sex: findings from the Wirral Child Health and Development Study (Journal article)
Braithwaite, E. C., Hill, J., Pickles, A., Glover, V., O'Donnell, K., & Sharp, H. (2018). Associations between maternal prenatal cortisol and fetal growth are specific to infant sex: findings from the Wirral Child Health and Development Study. JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE, 9(4), 425-431. doi:10.1017/S2040174418000181Maternal sensitivity to distress, attachment and the development of callous-unemotional traits in young children (Journal article)
Wright, N., Hill, J., Sharp, H., & Pickles, A. (2018). Maternal sensitivity to distress, attachment and the development of callous-unemotional traits in young children. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY, 59(7), 790-800. doi:10.1111/jcpp.12867The Regulation of Monoamine Oxidase A Gene Expression by Distinct Variable Number Tandem Repeats (Journal article)
Manca, M., Pessoa, V., Lopez, A. I., Harrison, P. T., Miyajima, F., Sharp, H., . . . Quinn, J. P. (2018). The Regulation of Monoamine Oxidase A Gene Expression by Distinct Variable Number Tandem Repeats. JOURNAL OF MOLECULAR NEUROSCIENCE, 64(3), 459-470. doi:10.1007/s12031-018-1044-z2017
Maternal mental health and child problem behaviours: disentangling the role of depression and borderline personality dysfunction (Journal article)
Huntley, F., Wright, N., Pickles, A., Sharp, H., & Hill, J. (2017). Maternal mental health and child problem behaviours: disentangling the role of depression and borderline personality dysfunction. BJPSYCH OPEN, 3(6), 300-305. doi:10.1192/bjpo.bp.117.005843Maternal depression and child behaviours: sex-dependent mediation by glucocorticoid receptor gene methylation in a longitudinal study from pregnancy to age 5 years (Preprint)
Sex differences in the associations between vagal reactivity and oppositional defiant disorder symptoms (Journal article)
Vidal-Ribas, P., Pickles, A., Tibu, F., Sharp, H., & Hill, J. (2017). Sex differences in the associations between vagal reactivity and oppositional defiant disorder symptoms. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY, 58(9), 988-997. doi:10.1111/jcpp.12750Maternal prenatal cortisol predicts infant negative emotionality in a sex-dependent manner (Journal article)
Braithwaite, E. C., Pickles, A., Sharp, H., Glover, V., O'Donnell, K. J., Tibu, F., & Hill, J. (2017). Maternal prenatal cortisol predicts infant negative emotionality in a sex-dependent manner. PHYSIOLOGY & BEHAVIOR, 175, 31-36. doi:10.1016/j.physbeh.2017.03.017Prenatal anxiety, maternal stroking in infancy, and symptoms of emotional and behavioral disorders at 3.5 years (Journal article)
Pickles, A., Sharp, H., Hellier, J., & Hill, J. (2017). Prenatal anxiety, maternal stroking in infancy, and symptoms of emotional and behavioral disorders at 3.5 years. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, 26(3), 325-334. doi:10.1007/s00787-016-0886-62016
The Team of Life: A narrative approach to building resilience in UK school children (Journal article)
Eames, V., Shippen, C., & Sharp, H. (2016). The Team of Life: A narrative approach to building resilience in UK school children. Educational and Child Psychology, 33(2), 57-68.2015
The Specific Role of Relationship Life Events in the Onset of Depression during Pregnancy and the Postpartum (Journal article)
Wright, N., Hill, J., Pickles, A., & Sharp, H. (2015). The Specific Role of Relationship Life Events in the Onset of Depression during Pregnancy and the Postpartum. PLOS ONE, 10(12). doi:10.1371/journal.pone.0144131Reduced Face Preference in Infancy: A Developmental Precursor to Callous-Unemotional Traits? (Journal article)
Bedford, R., Pickles, A., Sharp, H., Wright, N., & Hill, J. (2015). Reduced Face Preference in Infancy: A Developmental Precursor to Callous-Unemotional Traits?. Biological Psychiatry, 78(2), 144-150. doi:10.1016/j.biopsych.2014.09.022Effects of prenatal and postnatal depression, and maternal stroking, at the glucocorticoid receptor gene (Journal article)
Murgatroyd, C., Quinn, J., Sharp, H., Pickles, A., & Hill, J. (2015). Effects of prenatal and postnatal depression, and maternal stroking, at the glucocorticoid receptor gene. Translational Psychiatry, 5. doi:10.1038/tp.2014.140Maternal antenatal anxiety, postnatal stroking and emotional problems in children: outcomes predicted from pre- and postnatal programming hypotheses (Journal article)
Sharp, H., Hill, J., Hellier, J., & Pickles, A. (2015). Maternal antenatal anxiety, postnatal stroking and emotional problems in children: outcomes predicted from pre- and postnatal programming hypotheses. Psychological Medicine, 45(2), 269-283. doi:10.1017/S0033291714001342Conduct Disorders (Chapter 19) (Chapter)
Hill, J., & Sharp, H. (2015). Conduct Disorders (Chapter 19). In P. Luyten, L. C. Mayes, P. Fonagy, M. Target, & S. J. Blatt (Eds.), Handbook of contemporary psychodynamic approaches to psychopathology.. New York/London: The Guilford Press.Psychometric Properties of the Parent-Infant Caregiving Touch Scale (Journal article)
Koukounari, A., Pickles, A., Hill, J., & Sharp, H. (2015). Psychometric Properties of the Parent-Infant Caregiving Touch Scale. FRONTIERS IN PSYCHOLOGY, 6. doi:10.3389/fpsyg.2015.018872014
Evidence for sex differences in fetal programming of stress reactivity in infancy (Journal article)
Tibu, F., Hill, J., Sharp, H., Marshall, K., Glover, V., & Pickles, A. (2014). Evidence for sex differences in fetal programming of stress reactivity in infancy. Development and Psychopathology, 26(4 pt1), 879-888. doi:10.1017/S09545794140001942013
Evidence for interplay between genes and parenting on infant temperament in the first year of life: monoamine oxidase A polymorphism moderates effects of maternal sensitivity on infant anger proneness (Journal article)
Pickles, A., Hill, J., Breen, G., Quinn, J., Abbott, K., Jones, H., & Sharp, H. (2013). Evidence for interplay between genes and parenting on infant temperament in the first year of life: monoamine oxidase A polymorphism moderates effects of maternal sensitivity on infant anger proneness. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY, 54(12), 1308-1317. doi:10.1111/jcpp.12081Evidence for interplay between genes and maternal stress in utero: monoamine oxidase A polymorphism moderates effects of life events during pregnancy on infant negative emotionality at 5weeks (Journal article)
Hill, J., Breen, G., Quinn, J., Tibu, F., Sharp, H., & Pickles, A. (2013). Evidence for interplay between genes and maternal stress in utero: monoamine oxidase A polymorphism moderates effects of life events during pregnancy on infant negative emotionality at 5weeks. GENES BRAIN AND BEHAVIOR, 12(4), 388-396. doi:10.1111/gbb.120332012
Frequency of Infant Stroking Reported by Mothers Moderates the Effect of Prenatal Depression on Infant Behavioural and Physiological Outcomes (Journal article)
Sharp, H., Pickles, A., Meaney, M., Marshall, K., Tibu, F., & Hill, J. (2012). Frequency of Infant Stroking Reported by Mothers Moderates the Effect of Prenatal Depression on Infant Behavioural and Physiological Outcomes. PLOS ONE, 7(10). doi:10.1371/journal.pone.00454462010
Adversity and sex differences in social and emotional sensitivity in children, a possible mechanism for sex differences in psychiatric disorders (Journal article)
Hill, J., Sharp, H., & Murray, L. (2010). Adversity and sex differences in social and emotional sensitivity in children, a possible mechanism for sex differences in psychiatric disorders. Nature Precedings.Maternal and infant negative emotionality as predictors of mothers' capacity to preserve mind-mindedness during the still face (Conference Paper)
Hill, J., Sharp, H., Pickles, A., Marshall, K., Kelly, J., Bensinyor, M., & Hulbert, A. (2010). Maternal and infant negative emotionality as predictors of mothers' capacity to preserve mind-mindedness during the still face. In INFANT MENTAL HEALTH JOURNAL Vol. 31 (pp. 110). Retrieved from https://www.webofscience.com/Maternal emotion recognition during pregnancy and infant emotional negativity in early infancy (Conference Paper)
Hill, J., Sharp, H., Pickles, A., Marks, K., Sadler, C., Appleton, J., & Tibu, F. (2010). Maternal emotion recognition during pregnancy and infant emotional negativity in early infancy. In INFANT MENTAL HEALTH JOURNAL Vol. 31 (pp. 110-111). Retrieved from https://www.webofscience.com/Prenatal maternal psychosocial stress and preterm delivery: Interactions with infant gender? (Conference Paper)
Sharp, H., Lunt, K., Thompson, B., Bedwell, C., Jones, H., Pickles, A., & Hill, J. (2010). Prenatal maternal psychosocial stress and preterm delivery: Interactions with infant gender?. In INFANT MENTAL HEALTH JOURNAL Vol. 31 (pp. 111). Retrieved from https://www.webofscience.com/Sex differences in children's social and emotional sensitivity in response to an adversity; a possible mechanism for sex differences in psychopathology (Conference Paper)
Hill, J., Sharp, H., & Murray, L. (2010). Sex differences in children's social and emotional sensitivity in response to an adversity; a possible mechanism for sex differences in psychopathology. In INFANT MENTAL HEALTH JOURNAL Vol. 31 (pp. 110). Retrieved from https://www.webofscience.com/2009
The dynamics of threat, fear and intentionality in the conduct disorders: longitudinal findings in the children of women with post-natal depression (Chapter)
Hill, J., Murray, L., Leidecker, V., & Sharp, H. (2009). The dynamics of threat, fear and intentionality in the conduct disorders: longitudinal findings in the children of women with post-natal depression. In S. Hodgins, E. Viding, & A. Plodowski (Eds.), Persistent Violent Offenders: Neuroscience and Rehabilitation. (pp. 101-122). Oxford: Oxford University Press.2008
The dynamics of threat, fear and intentionality in the conduct disorders: longitudinal findings in the children of women with post-natal depression (Journal article)
Hill, J., Murray, L., Leidecker, V., & Sharp, H. (2008). The dynamics of threat, fear and intentionality in the conduct disorders: longitudinal findings in the children of women with post-natal depression. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 363(1503), 2529-2541. doi:10.1098/rstb.2008.00362005
The Antenatal Maternal Orientation Measure (Chapter)
Sharp, H. M. (2005). The Antenatal Maternal Orientation Measure. In J. Raphael-Leff (Ed.), Psychological Processes in Childbearing (pp. 586-590). London: Chapman and Hall.2004
An empirical evaluation of a psychoanalytic theory of mothering orientation: implications for the antenatal prediction of postnatal depression (Journal article)
Sharp, H. M., & Bramwell, R. (2004). An empirical evaluation of a psychoanalytic theory of mothering orientation: implications for the antenatal prediction of postnatal depression. JOURNAL OF REPRODUCTIVE AND INFANT PSYCHOLOGY, 22(2), 71-89. doi:10.1080/02646830420002059452000
Obsessive-compulsive disorder with delusions (Journal article)
Fear, C., Sharp, H., & Healy, D. (2000). Obsessive-compulsive disorder with delusions. PSYCHOPATHOLOGY, 33(2), 55-61. doi:10.1159/0000291211998
Symptoms or side effects? Methodological hazards and therapeutic principles (Journal article)
Sharp, H. M., Healy, D., & Fear, C. F. (1998). Symptoms or side effects? Methodological hazards and therapeutic principles. HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, 13(7), 467-475. doi:3.3.CO;2-I">10.1002/(SICI)1099-1077(1998100)13:7<467::AID-HUP21>3.3.CO;2-IDOI: 10.1002/(SICI)1099-1077(1998100)13:7<467::AID-HUP21>3.3.CO;2-I