Sample preparation

Sample preflight checklist for LCMS

One of the driving principles in a lot of our work is ‘defend the instrument from the sample’! It is all too easy to cause a significant amount of LCMS downtime by a) overloading a system by not understanding the relationship between load and complexity, b) by not adopting one of our standard protocols, c) by not checking that you have complete digestion, d) by forgetting about components that persist in the workflow (e.g. detergents), e) instructing particulates and lastly, by not taking enough responsibility and care, or consideration for the person following you. This check list is meant to be a helpful guide to prevent most of the common pitfalls. Remember, if you are in any doubt, than ASK! Read More...