Photo of Professor Thomas Solomon

Professor Thomas Solomon CBE FRCP FMedSci

Director of The Pandemic Institute, Chair of Neurology and Director of the National Institute for Health and Care Research Health Protection Research Unit in Emerging and Zoonotic Infections Clinical Infection, Microbiology & Immunology

Research

Research Interest 1

Brain Infections, both in the UK and Overseas

Research Group Membership

Research Grants

Using whole proteome and host gene expression analysis to improve diagnostic strategies in encephalitis.

ASSOCIATION OF BRITISH NEUROLOGISTS (UK)

September 2016 - June 2021

The COVID-19: Clinical Neuroscience Study (COVID-CNS)

UK RESEARCH AND INNOVATION

October 2020 - October 2022

Reducing the disease burden of stroke in HIV-endemic Malawi (Proposal and Partnership Development Award)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2020 - September 2020

Investigating the mechanisms involved in HIV infection and cerebral endothelial dysfunction in a 3D human brain neurovascular spheroid

WELLCOME TRUST (UK)

January 2021 - December 2025

COVID-19 Neurological Disease: a Global Meta-Analysis and Prospective Case Control Study in Brazil, India and Malawi. (COVID-Neuro)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

October 2020 - March 2023

NIHR Senior Investigator

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2023 - March 2026

Early social care needs of people who have had encephalitis

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2020 - April 2026

NIHR Health Protection Research Unit in Emerging and Zoonotic Infections (HPRU EZI)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2020 - March 2025

COVID-19: nCoV: Understanding the dynamics of policy development and healthcare worker behaviour in the UK during the Covid-19 public health emergency

UK RESEARCH AND INNOVATION

March 2020 - September 2021

CCP - UK

MEDICAL RESEARCH COUNCIL

March 2020 - September 2022

Improving diagnosis of brain infections in Indonesia using novel and established molecular diagnostic tools.

DEPARTMENT FOR BUSINESS, ENERGY AND INDUSTRIAL STRATEGY (BEIS) (UK)

April 2019 - March 2023

NIHR Global Health Research Group on Improving the Management of Acute Brain Infections at University of Liverpool

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2018 - December 2022

A phase I study of recombinant poxvirus Zika vaccines

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

September 2017 - March 2022

Recovery and rehabilitation in encephalitis, what are the long-term neuropsychological, cognitive and behavioural outcomes and can they be predicted?

ENCEPHALITIS INTERNATIONAL (UK)

April 2017 - March 2022

Development of a novel blood test to aid the diagnosis of bacterial meningitis (TRIM)

MEDICAL RESEARCH COUNCIL

April 2019 - December 2025

Research Capability Funding

THE WALTON CENTRE NHS FOUNDATION TRUST (UK)

May 2017 - March 2018

Adjuvant free vaccines and companion diagnostics to control emerging flaviviruses

INNOVATE UK (UK)

May 2017 - April 2018

Zika Preparedness Latin American Network — ZikaPLAN

EUROPEAN COMMISSION

October 2016 - March 2021

Understanding cross-reactive immunity to Japanese encephalitis virus (FlaviPrime)

WELLCOME TRUST (UK)

July 2017 - June 2022

One Health Research Network for the Horn of Africa (HORN)

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

October 2017 - March 2023

The pathophysiology and outcome of HIV-associated vasculopathy and stroke in sub-saharan Africa.

WELLCOME TRUST (UK)

September 2015 - March 2018

Interaction of Japanese Encephalitis Virus with cells of the Blood Brain Barrier - an in vitro model (Chitra Pattabiraman)

DEPARTMENT FOR BUSINESS, INNOVATION AND SKILLS (UK)

June 2016 - June 2018

2014 allocation - Wellcome ISSF non clinical fellowships

WELLCOME TRUST (UK)

May 2015 - October 2018

Intravenous immunoglobulin in the management of encephalitis in children.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

January 2015 - December 2019

Zika: susceptibility of vectors to infection and influence of temperature on the extrinsic incubation period

DEPARTMENT FOR BUSINESS, ENERGY AND INDUSTRIAL STRATEGY (BEIS) (UK)

April 2016 - September 2017

Investigating the link between Zika virus infection and neurological disease in ex vivo and in vivo models

DEPARTMENT FOR BUSINESS, ENERGY AND INDUSTRIAL STRATEGY (BEIS) (UK)

March 2016 - March 2017

Identifying immunomodulatory targets to reduce leucocyte infiltration in viral encephalitis

BRITISH MEDICAL ASSOCIATION (UK), THE ACADEMY OF MEDICAL SCIENCES (UK)

July 2016 - January 2018

Research Capability Funding: Sylviane Defres.

THE WALTON CENTRE NHS FOUNDATION TRUST (UK)

August 2015 - March 2016

RCF Funding for Dr Gosia Wnek

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

May 2016 - March 2017

A prospective case-control study to examine the role of Zika virus in Guillain-Barre syndrome in Brazil.

DEPARTMENT FOR BUSINESS, ENERGY AND INDUSTRIAL STRATEGY (BEIS) (UK)

January 2017 - September 2017

PHD Placement Programme

DEPARTMENT FOR BUSINESS, INNOVATION AND SKILLS (UK)

April 2015 - February 2016

Non-invasive measurement of intracranial pressure and cerebral oxygenation in paediatric brain injury.

UK CHILDREN'S NEUROLOGICAL RESEARCH CAMPAIGN (UK)

September 2014 - August 2015

YEAR 1 Wellcome Trust ISSF Non-Clinical Fellowships

WELLCOME TRUST (UK)

October 2011 - May 2018

Establishing research infrastructure for the Brain Infections UK portfolio of studies investigating central nervous system infections within WCTF and across the UK.

THE WALTON CENTRE NHS FOUNDATION TRUST (UK)

March 2012 - March 2013

Human Lymphocyte Responses in Japanese encephatitis.

THE PATHOLOGICAL SOCIETY (UK)

March 2001 - February 2003

The British Antibiotic and Silver Impregnated Catheters for ventriculoperitoneal Shunts multi-centre randomised controlled trial (The BASICS trial)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

June 2012 - February 2019

A Preliminary Examination Of The Role Of The Inflammatory Response In The Pathogenesis Of Encephalitis (Proposal for a Follow on Study from the Health Protection Agency (HPA) study of the Aetiology of Encephalitis in England)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

March 2010 - March 2012

Enterovirus-71 associated hand foot mouth disease in Sarawak: relationship between viral load, human immune response and disease severity.

WELLCOME TRUST (UK)

June 2005 - February 2009

Study of host susceptibility and strain virulence in the pathogenesis of Japanese encephalitis.

WELLCOME TRUST (UK)

August 1999 - July 2006

The Kirkby Foundation- Encephalitis Society PhD Studentship

THE KIRKBY FOUNDATION (UK)

July 2014 - June 2017

Mosquitoes and the spread of arboviruses: What is the threat to UK horses?

THE HORSE TRUST (UK)

September 2014 - August 2017

Application of high throughput genomic science technologies to NIHR research programmes

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

September 2010 - September 2013

Value in People Award 2005.

WELLCOME TRUST (UK)

October 2005 - September 2009

Health Protection Research Unit: Emerging Infections (including zoonoses) and Biological Threats. (HPRU)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2014 - March 2020

YEAR 1 (part2) Wellcome Trust ISSF Non-Clinical Fellowships

WELLCOME TRUST (UK)

October 2012 - March 2023

Algorithm for Clinical Diagnosis of Tuberculous Meningitis in the UK.

GUARANTORS OF BRAIN (UK)

April 2010 - April 2011

Herpes virus meningitis in adults

MENINGITIS RESEARCH FOUNDATION (UK)

April 2011 - April 2014

Development of a human ex-vivo blood brain barrier model to study viral encephalitis.

HADWEN TRUST, DR FOR HUMANE RESEARCH

September 2009 - August 2012

Central nervous system infections at Queen Elizabeth Central Hospital Paediatric Unit.

WELLCOME TRUST (UK)

March 2002 - August 2006

Bardatin Aifa - bench fees

MINISTRY OF FINANCE (INDONESIA)

October 2014 - September 2018

Understanding and Improving the outcome of Viral Encephalitis (ENCEPH UK Neuropsychology Sub Study)

ENCEPHALITIS INTERNATIONAL (UK)

February 2015 - December 2016

Improving the diagnosis of patients with central nervous system infections in partnership with Fast Track Diagnostics.

FAST TRACK DIAGNOSTICS RESEARCH LIMITED (UK)

May 2014 - March 2025

Late social care needs of people who have had encephalitis

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

January 2021 - August 2024

Vector competence of British mosquitoes to flaviviruses.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

November 2013 - November 2017

Developing minocycline as a novel anti-apoptotic treatment for Herpes Simplex Virus encephalitis

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

March 2010 - March 2012

Predicting the effects of climate change on infectious diseases of animals

LEVERHULME TRUST (UK)

October 2007 - March 2013

Inflammation in Japanese Encephalitis.

MEDICAL RESEARCH COUNCIL

November 2005 - April 2011

Bridging and accelerating the translation of novel scientific findings for health and wealth gain

MEDICAL RESEARCH COUNCIL

March 2014 - August 2015

Research Collaborations

External: The Centre for Integrated Genomic Medical Research (CIGMR)

External: National Institute for Mental Health & Neurological Science (NIMHANS), Bangalore

External: Queen Elizabeth Hospital, Blantyre, Malawi

Clinical Virology Unit

External: University of Manchester, UK

External: Rabies and Wildlife Zoonoses Group, Veterinary Laboratories Agency (Weybridge)

External: University of Texas Medical Branch, Galveston, Texas

Wellcome Trust Centre for Human Genetics

External: The University of Oxford

External: Universiti Malaysia Sarawak

External: University of Oxford-Wellcome Trust Clinical Research Unit, Vietnam

External: Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand