Publications

2021

Journal Papers

'Medipix3 for dosimetry and real-time beam monitoring: first tests at a 60 MeV proton therapy facility'J.S.L. Yap, N.J.S. Bal, A. Kacperek, J. Resta López and C.P. Welsch, Journal of Instrumentation, Volume 16, November 2021
https://doi.org/10.1088/1748-0221/16/11/T11001

 

2020

Journal Papers

'Benchmarking of FLUKA production cross sections of positron emission tomography isotopes for in-vivo range verification in hadron therapy'G. Arico, et al., EPJ Web Conf 239 (2020), https://doi.org/10.1051/epjconf/202023924001

'Beamline characterization of a dielectric-filled reentrant cavity resonator as beam current monitor for a medical cyclotron facility', Sudharsan Srinivasan, Pierre-André Duperrex, Jacobus Maarten Schippers, Physica Medica 78 (2020): 101-108. https://doi.org/10.1016/j.ejmp.2020.09.006

'Technical challenges for FLASH proton therapy', Simon Jolly, Hywel Owen, Marco Schipper, Carsten Welsch, Physica Medica 78 (2020): 71-82. https://doi.org/10.1016/j.ejmp.2020.08.005

'Beam characterisation studies of the 62 MeV proton therapy beamline at the Clatterbridge Cancer Centre', Jacinta Yap, Javier Resta-López, Andrzej Kacperek, Roland Schnuerer, Simon Jolly, Stewart Boogert, Carsten Welsch, Physica Medica 77 (2020): 108-120. https://doi.org/10.1016/j.ejmp.2020.08.002

'A modular dose delivery system for treating moving targets with scanned ion beams: Performance and safety characteristics, and preliminary tests', Michelle Lis, Marco Donetti, Wayne Newhauser, Marco Durante, Joyoni Dey, Ulrich Weber, Moritz Wolf, Timo Steinsberger, Christian Graeff, Physica Medica 76 (2020):307-316. https://doi.org/10.1016/j.ejmp.2020.07.029

'Geometry optimisation of graphite energy degrader for proton therapy', Oponowicz, E., H. L. Owen, S. Psoroulas, and D. Meer. " Physica Medica 76 (2020): 227-235. DOI: 10.1016/j.ejmp.2020.06.023

'A scintillator-based range telescope for particle therapy’, Laurent Kelleter, Raffaella Radogna, Lennart Volz, Derek Attree, Anastasia Basharina-Freshville, Joao Seco, Ruben Saakyan and Simon Jolly, Physics in Medicine & Biology (2020). https://doi.org/10.1088/1361-6560/ab9415

‘Preparation of a radiobiology beam line at the 18 MeV proton cyclotron facility at CNA’,  Anna Baratto-Roldán, María del Carmen Jiménez-Ramosa, Sonia Jimeno, Pablo Huertas, Javier García-López, María Isabel Gallardo, Miguel Antonio Cortés-Giraldo, José Manuel Espino, Physica Medica 74, 19–29 (2020). https://doi.org/10.1016/j.ejmp.2020.04.022

‘Organ motion quantification and margins evaluation in carbon ion therapy of abdominal lesions’, Charalampos Kalantzopoulos, Giorgia Meschini, Chiara Paganelli, Giulia Fontana, Alessandro Vai, Lorenzo Preda, Viviana Vitolo, Francesca Valvo, Guido Baroni, Physica Medica 75, 33–39 (2020). https://doi.org/10.1016/j.ejmp.2020.05.014

Optimization of Medical Accelerators, edited by Marco Durante, Christian Graeff, Carsten Welsch, Physica Medica Focus Issue (2020) 

‘A new treatment planning approach accounting for prompt gamma range verification and interfractional anatomical changes‘, Liheng Tian, Guillaume Landry, George Dedes, Marco Pinto, Florian Kamp, Claus Belka and Katia Parodi, Physics in Medicine & Biology 65, 095005 (2020). https://doi.org/10.1088/1361-6560/ab7d15

‘In Vivo Validation of the BIANCA Biophysical Model: Benchmarking against Rat Spinal Cord RBE Data’, Mario P. Carante, Giulia Aricò, Alfredo Ferrari, Christian P. Karger, Wioletta Kozlowska, Andrea Mairani, Paola Sala and Francesca Ballarini, International Journal of Molecular Sciences 21(11), 3973 (2020). https://doi.org/10.3390/ijms21113973

‘Non-invasive beam profile monitor for medical accelerators‘, N. Kumar, A. Salehilashkajani, H.D. Zhang, M. Ady, P. Forck, J. Glutting, O.R. Jones, R. Kersevan, T. Marriott-Doddington, S. Mazzoni, A. Rossi, G. Schneider, S. Udrea, R. Veness, C.P. Welsch, Physica Medica 73, 173–178 (2020). https://doi.org/10.1016/j.ejmp.2020.04.023

'Experimental exploration of a mixed helium/carbon beam for online treatment monitoring in carbon ion beam therapy', Lennart Volz, Laurent Kelleter, Stephan Brons, Lucas N Burigo, Christian Graeff, Nina Isabell Niebuhr, Raffaella Radogna, Stefan Scheloske, Christian Schömers, Simon Jolly and Joao Seco, Physics in Medicine & Biology 65(5) (2020), https://doi.org/10.1088/1361-6560/ab6e52

'A mathematical expression for depth‐light curves of therapeutic proton beams in a quenching scintillator'Kelleter, Laurent. and Jolly, Simon,  Med. Phys.. Accepted Author Manuscript. (2020) doi:10.1002/mp.14099

 

2019

Journal Papers

'First benchmarking of the BIANCA model for cell survival predictions in a clinical hadron therapy scenario', M. Carante, G. Aricò, A. Ferrari, W. Kozlowska, A. Mairani and F. Ballarini, Physics in Medicine & Biology 64, 215008 (2019) https://doi.org/10.1088/1361-6560/ab490f

'Measurement of PET isotope production cross sections for protons and carbon ions on carbon and oxygen targets for applications in particle therapy range verification', F. Horst, W. Adi, G. Aricò, K.-T. Brinkmann, M. Durante, C.-A. Reidel, M. Rovituso, U. Weber, H.-G. Zaunick, K. Zink and C. Schuy, Physics in Medicine & Biology 64, 205012 (2019) https://doi.org/10.1088/1361-6560/ab4511

'Measurement of 4He charge- and mass-changing cross sections on H, C, O and Si targets in the energy range 70−220 MeV/u for radiation transport calculations in ion-beam therapy', F. Horst , G. Aricò, K.-T. Brinkmann, S. Brons, A. Ferrari, T. Haberer, A. Mairani, K. Parodi, C.-A. Reidel, U. Weber, K. Zink, C. Schuy, Physical Review C 99, 014603 (2019)  http://doi.org/10.1103/PhysRevC.99.014603

'Processing of prompt gamma-ray timing data for proton range measurements at a clinical beam delivery', Theresa Werner, Johannes Petzoldt et al., Physics in Medicine & Biology 64(10), 105023 (2019) https://doi.org/10.1088/1361-6560/ab176d

'Range verification in proton therapy: Can prompt-gamma imaging identify the source of deviation?', Chirasak Khamfongkhruea, Johannes Petzoldt et al., Radiotherapy and Oncology 133 (Supplement 1), S296–S297 (2019) https://doi.org/10.1016/S0167-8140(19)30986-7

'Parametrising microdosimetric distributions of mono-energetic proton beams for fast estimates of yD and y*', Álvaro Perales, Anna Baratto-Roldán, Peter Kimstrand, Miguel A. Cortés-Giraldo and Alejandro Carabe, Biomedical Physics & Engineering Express 5(4), 045014 (2019) https://doi.org/10.1088/2057-1976/ab236a

'Comparison of proton range predictions between Single- and Dual-Energy CT using prompt gamma imaging', Teo Boon-Keng, Johannes Petzoldt et al., Radiotherapy and Oncology 133 (Supplement 1), S95–S96 (2019) https://doi.org/10.1016/S0167-8140(19)30607-3

'Segment-averaged LET concept and analytical calculation from microdosimetric quantities in proton radiation therapy', Alejandro Bertolet, Anna Baratto-Roldán, Miguel A. Cortés Giraldo, Alejandro Carabe, Medical Physics, 46(9), 4204-4214 (2019) https://doi.org/10.1002/mp.13673

'Dose-averaged LET calculation for proton track segments using microdosimetric Monte Carlo simulations', Alejandro Bertolet, Anna Baratto-Roldán, Sofia Barbieri, Giorgio Baiocco, Alejandro Carabe, Miguel A. Cortes-Giraldo, Medical Physics, 46(9), 4184-4192 (2019) https://doi.org/10.1002/mp.13643

'Technical Note: Simulation of dose buildup in proton pencil beams', L. Kelleter,  B. Zhen‐Hong Tham , R. Saakyan, J. Griffiths, R. Amos,S. Jolly and A. Gibson, Med. Phys., 46: 3734-3738. (2019) doi:10.1002/mp.13660

'Development of the LHCb VELO Detector Modules into a Standalone, Non-Invasive Online Beam Monitor for Medical Accelerators', R. Schnuerer, J. Yap, H. Zhang, T. Cybulski, T. Smith, G. Haefeli, O. Girard, T. Szumlak and C. Welsch, Instruments 2019, 3(1), 1; https://doi.org/10.3390/instruments3010001

 

Conference Contributions

'Dark Current Analysis at CERN’s X-band Facility', D. Banon-Caballero, A. Vnuchenko, M. Boronat, N. Catalán Lasheras, A. Faus-Golfe, B. Gimeno, W. Wuensch et al., Proceedings IPAC'19, 10th International Particle Accelerator Conference, Melbourne, Australia (2019) https://doi.org/10.18429/JACoW-IPAC2019-WEPRB059

'Developments of the nuclear reaction and fragmentation models in FLUKA for ion collisions at therapeutic energies', G. Aricò, A. Ferrari, F. Horst, A. Mairani, C.-A. Reidel, C. Schuy, U. Weber, Proceedings of the 15th International Conference on Nuclear Reaction Mechanisms, Varenna, Italia, (2018), CERN Proceedings 1, 321-326 (2019) http://cds.cern.ch/record/2669357

'Superconducting Dipole Design for a Proton Computed Tomography Gantry'E. Oponowicz, H. Owen, Proceedings IPAC'19, 10th International Particle Accelerator Conference, Melbourne, Australia (2019) https://doi.org/10.18429/JACoW-IPAC2019-THPMP054

'Beam Characterisation Using MEDIPIX3 and EBT3 Film at the Clatterbridge Proton Therapy Beamline', J. S.L. Yap, N. J. S. Bal, A. Kacperek, J. Resta-Lopez, C.P. Welsch et al., Proceedings IPAC'19, 10th International Particle Accelerator Conference, Melbourne, Australia (2019) https://doi.org/10.18429/JACoW-IPAC2019-THPMP033

'Non-Invasive beam monitoring using LHCb VELO with 40 MeV protons', R. Schnuerer, J S.L. Yap, H. Zhang, T. Szumlak, T. Price and C.P. Welsch, Proceedings IPAC'19, 10th International Particle Accelerator Conference, Melbourne, Australia (2019) https://doi.org/10.18429/JACoW-IPAC2019-THPMP043

'Quadrated dielectric-filled reentrant cavity resonator as a proton beam position diagnostic', S. Srinivasan, P. A. Duperrex, J. M. Schippers, Proceedings IPAC'19, 10th International Particle Accelerator Conference, Melbourne, Australia (2019) https://doi.org/10.18429/JACoW-IPAC2019-WEPGW083

 

2018

Journal Papers

'Feasibility Study of a Proton Irradiation Facility for Radiobiological Measurements at an 18 MeV Cyclotron', Anna Baratto-Roldán, M. Carmen Jiménez-Ramos, M. Cristina Battaglia, Javier García-Lopez, M. Isabel Gallardo, Miguel A. Cortés-Giraldo, José M. Espino. Instruments 2018, 2, 26. https://doi.org/10.3390/instruments2040026

'Dielectric-Filled Reentrant Cavity Resonator as a Low-Intensity Proton Beam Diagnostic', Sudharsan Srinivasan, Pierre-André Duperrex, Instruments 2018, 2(4), 24; https://doi.org/10.3390/instruments2040024

'Correction of Geometrical Effects of a Knife-Edge Slit Camera for Prompt Gamma-Based Range Verification in Proton Therapy',Johannes Petzoldt, Guillaume Janssens, Lena Nenoff, Christian Richter and Julien Smeets  Paper  Instruments 2018, 2(4), 25; https://doi.org/10.3390/instruments2040025

'Toward a new treatment planning approach accounting for in-vivo proton range verification'Liheng Tian, Guillaume Landry, Georgios Dedes, Florian Kamp, Marco Pinto, Katharina Niepel, Claus Belka, Katia Parodi, October 2018, Physics in Medicine and Biology 63(21) DOI:10.1088/1361-6560/aae749 

'Measurement of 4He charge- and mass-changing cross sections on H, C, O, and Si targets in the energy range 70--220 MeV/u for radiation transport calculations in ion-beam therapy', Felix Horst, Giulia Arico', Kai-Thomas Brinkmann, et al., https://doi.org/10.1103/PhysRevC.99.014603

'Construction and Commissioning of the S-Band High-Gradient RF Laboratory at IFIC' ,D. Esperante, C. Blanch, M. Boronat, J. Fuster, D. Gonzalez Iglesias, A. Vnuchenko, B. Gimeno et al, Journal of Physics: Conf. Series 1067, 082024 (2018) https://doi.org/10.1088/1742-6596/1067/8/082024

'From range measurements to dose: in-vivo dosimetry using the prompt gamma camera,, Simona Toscano, Johannes Petzoldt et al., Radiotherapy and Oncology 127 (Supplement 1), S40 (2018) https://doi.org/10.1016/S0167-8140(18)30391-8

'Prompt Gamma Imaging for the identification of regional proton range deviations due to anatomic change in a heterogeneous region', Yunhe Xie, Johannes Petzoldt et al., Radiotherapy and Oncology 127 (Supplement 1), S967-S968 (2018) https://doi.org/10.1016/S0167-8140(18)32110-8

 

Conference Contributions

'Re-entrant cavity resonator for low intensities proton beam measurements', S. Srinivasan, P. A. Duperrex,  IPAC 2018 Conference Proceedings, Vancouver, Canada https://doi:10.18429/JACoW-IPAC2018-WEPAL069

'High Power Conditioning of X-Band RF Components', N. Catalan-Lasheras, H. Damerau, R. Gerard, V. del Pozo Romano, A. Vnuchenko et al., Proceedings IPAC’18, 9th International Particle Accelerator Conference, Vancouver, Canada (2018) https://doi.org/10.18429/JACoW-IPAC2018-WEPMF074

'Initial Testing of Techniques for Large Scale Rf Conditioning for the Compact Linear Collider', T. G. Lucas, M. Boland, A. Grudiev,  A. Vnuchenko, W. Wuensch, R. Zennaro, et al., Proceedings IPAC’18, 9th International Particle Accelerator Conference,  Vancouver, Canada (2018) https://doi.org/10.18429/JACoW-IPAC2018-THPMK103

'High Power and High Repetition Rate X-band Power Source Using Multiple Klystrons', M. Volpi, M. Boland, C. Serpico, A. Vnuchenko, W. Wuensch et al., Proceedings IPAC’18, 9th International Particle Accelerator Conference, Vancouver, Canada (2018) https://doi.org/10.18429/JACoW-IPAC2018-THPMK104

'Implementation of a non-invasive online beam monitor at a 60 MeV proton therapy beamline', R. Schnuerer, J S.L. Yap, H. Zhang, G.J. Haefeli, O. Girard and C.P. Welsch, IPAC 2018 Conference Proceedings, Vancouver, Canada doi:10.18429/JACoW-IPAC2018-MOPML024

'Toward a new treatment planning system accounting for in-vivo proton range verification in proton therapy', Liheng Tian, Georgios Dedes, Guillaume Landry, Florian Kamp, Katharina Niepel, Claus Belka, Katia Parodi, ECMP (European Congress of Medical Physics) 2018, August 2018

'High Gradient Performance of an S-Band Backward Traveling Wave Accelerating Structure for Medical Hadron Therapy Accelerators', Anna Vnuchenko, IPAC 2018, Vancouver, Canada http://ipac2018.vrws.de/papers/mopml043.pdf.  

'Start-to-End Beam Dynamic Simulations for PRAE', Anna Vnuchenko, IPAC 2018, Vancouver, Canada doi:10.18429/JACoW-IPAC2018-MOPML044

 

2017

Journal Papers

‘Sensitivity of a prompt-gamma slit-camera to detect range shifts for proton treatment verification’, Lena Nenoff, Marlen Priegnitz, Guillaume Janssens, Johannes Petzoldt, Patrick Wohlfahrt, Anna Trezza, Julien Smeets, Guntram Pausch, Christian Richter, Radiotherapy and Oncology, Volume 125, Issue 3, December 2017, Pages 534-540, DOI: https://doi.org/10.1016/j.radonc.2017.10.013 

'Prompt Gamma Rays Detected With a BGO Block Compton Camera Reveal Range Deviations of Therapeutic Proton Beams', Fernando Hueso-González, Johannes Petzoldt et al., IEEE Transactions on Radiation and Plasma Medical Sciences 1(1), 76 – 86 (2017) https://doi.org/10.1109/TNS.2016.2622162

'The AD and ELENA orbit, trajectory and intensity measurement systems', R. Marco-Hernández, D. Alves, M.E. Angoletta, O. Marqversen, J. Molendijk, E. Oponowicz, R. Ruffieux, J. Sánchez-Quesada and L. SØby, Journal of Instrumentation 12, P07024 (2017) https://doi.org/10.1088/1748-0221/12/07/P07024

 

Conference Contributions

'Abstract ID: 196 Relation between dose average linear energy transfer and dose mean lineal energy calculated for proton therapy beams off axis: A study with the Geant4 toolkit', Anna Baratto-Roldán, Peter Kimstrand, Álvaro Perales Molina, Alejandro Carabe, Miguel Antonio Cortés-Giraldo, Physica Medica: European Journal of Medical Physics , Volume 42 , 42 – 43, International Conference on Monte Carlo Techniques for Medical Applications – 2017 (Naples, Italy, October 2017). http://dx.doi.org/10.1016/j.ejmp.2017.09.104

'Non-Invasive Online Beam Monitor Using LHCb VELO', R. Schnuerer, J S.L. Yap, H. Zhang, C.P. Welsch, Proceedings IPAC’17, 8th International Particle Accelerator Conference, Copenhagen, Denmark (2017) https://doi.org/10.18429/JACoW-IPAC2017-THPVA136

'Design and Construction of a High-Gradient RF Lab at IFIC-Valencia', N. Catalan Lasheras, G. Mcmonagle, I. Syratchev, W. Wuensch, A. Faus Golfe, T. Argyropoulos, C. Blanch, D. Esperante, J. Giner, A. Vnuchenko, Proc. IPAC17, Copenhagen, Denmark (2017) https://doi.org/10.18429/JACoW-IPAC2017-THPIK081

'Upgrade Study of the MedAustron Ion Beam Center', A. De Franco, et al., Proc. IPAC17, Copenhagen, Denmark (2017) https://doi.org/10.18429/JACoW-IPAC2017-THPVA074

'Superconducting Gantry Design for Proton Tomography', E. Oponowicz, H.Owen, Proc. IPAC17, Copenhagen, Denmark (2017) https://doi.org/10.18429/JACoW-IPAC2017-THPVA140

'Design and Construction of a High-Gradient RF Lab at IFIC-Valencia', Anna Vnuchenko, IPAC 2017. Copenhagen, Denmark, https://doi.org/10.18429/JACoW-IPAC2017-THPIK081

'First Optics Design and Beam Performance Simulation of PRAE: Platform for Research and Applications With Electrons at Orsay', Anna Vnuchenko, IPAC 2017. Copenhagen, Denmark https://doi.org/10.18429/JACoW-IPAC2017-THPVA079

'Range Verification in Proton Therapy by Prompt Gamma-Ray Timing (PGT): Steps towards Clinical Implementation' ,Theresa Werner, Johannes Petzoldt et al., IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), Atlanta, USA (2017) https://doi.org/10.1109/NSSMIC.2017.8532807

 

2016

Conference Contributions

'Optimized Cryogenic Current Comparator for CERN's Low-Energy Antiproton Facilities' ,M. Fernandes, A. Lees, D. Alves, T. Koettig, E. Oponowicz, J. Tan, C. Welsch, R. Geithner, R. Neubert, T. Stöhlker, M. Schwickert, Proceedings IBIC’16, 5th International Beam Instrumentation Conference, Barcelona, Spain (2016) https://doi.org/10.18429/JACoW-IBIC2016-MOPG48