Professor Rachel Williams BSc MS PhD CEng MIPEM FIMMM
Professor of Ophthalmic Bioengineering Eye & Vision Sciences
- +44 (0)151 794 9043
- Work email Rlw@liverpool.ac.uk
Publications
Selected Publications
- Novel Heavy Tamponade for Vitreoretinal Surgery (Journal article - 2013)
- A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens (Journal article - 2016)
- The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry (Journal article - 2017)
- Biomaterials for Regenerative Medicine Approaches for the Anterior Segment of the Eye (Journal article - 2018)
- Development of decellularized conjunctiva as a substrate for the ex vivo expansion of conjunctival epithelium (Journal article - 2018)
2021
The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration. (Journal article)
Makuloluwa, A. K., Hamill, K. J., Rauz, S., Bosworth, L., Haneef, A., Romano, V., . . . Kaye, S. B. (2021). The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration.. The ocular surface. doi:10.1016/j.jtos.2021.05.011
Characterization of Tunable Poly-e-Lysine-Based Hydrogels for Corneal Tissue Engineering. (Journal article)
Lace, R., Duffy, G. L., Gallagher, A. G., Doherty, K. G., Maklad, O., Wellings, D. A., & Williams, R. L. (2021). Characterization of Tunable Poly-epsilon-Lysine-Based Hydrogels for Corneal Tissue Engineering. MACROMOLECULAR BIOSCIENCE. doi:10.1002/mabi.202100036
Chemical Cross-Linking of Corneal Tissue to Reduce Progression of Loss of Sight in Patients With Keratoconus (Journal article)
Haneef, A., Gopalan, R. O. G., Rajendran, D. T., Nunes, J., Kuppamuthu, D., Radhakrishnan, N., . . . Williams, R. (2021). Chemical Cross-Linking of Corneal Tissue to Reduce Progression of Loss of Sight in Patients With Keratoconus. TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 10(5). doi:10.1167/tvst.10.5.6
Material Characterisation and Stratification of Conjunctival Epithelial Cells on Electrospun Poly(e-Caprolactone) Fibres Loaded with Decellularised Tissue Matrices. (Journal article)
Bosworth, L. A., Doherty, K. G., Hsuan, J. D., Cray, S. P., D'Sa, R. A., Pineda Molina, C., . . . Williams, R. L. (2021). Material Characterisation and Stratification of Conjunctival Epithelial Cells on Electrospun Poly(e-Caprolactone) Fibres Loaded with Decellularised Tissue Matrices.. Pharmaceutics, 13(3). doi:10.3390/pharmaceutics13030318
2020
A human retinal microvascular endothelial-pericyte co-culture model to study diabetic retinopathy in vitro (Journal article)
Eyre, J. J., Williams, R. L., & Levis, H. J. (2020). A human retinal microvascular endothelial-pericyte co-culture model to study diabetic retinopathy in vitro. EXPERIMENTAL EYE RESEARCH, 201. doi:10.1016/j.exer.2020.108293
Plasma polymer surface modified expanded polytetrafluoroethylene promotes epithelial monolayer formation in vitro and can be transplanted into the dystrophic rat subretinal space (Journal article)
Nian, S., Kearns, V. R., Wong, D. S. H., Bachhuka, A., Vasilev, K., Williams, R. L., . . . Sheridan, C. M. (2021). Plasma polymer surface modified expanded polytetrafluoroethylene promotes epithelial monolayer formation in vitro and can be transplanted into the dystrophic rat subretinal space. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 15(1), 49-62. doi:10.1002/term.3154
Exploratory use of fluorescent SmartProbes for the rapid detection of microbial isolates causing corneal ulcer. (Journal article)
Gunasekaran, R., Lalitha, P., Megia-Fernandez, A., Bradley, M., Williams, R. L., Dhaliwal, K., . . . Mills, B. (n.d.). Exploratory use of fluorescent SmartProbes for the rapid detection of microbial isolates causing corneal ulcer.. American journal of ophthalmology. doi:10.1016/j.ajo.2020.06.014
Poly-e-Lysine or Mel4 Antimicrobial Surface Modification on a Novel Peptide Hydrogel Bandage Contact Lens (Journal article)
Lace, R., Doherty, K., Dutta, D., Willcox, M., & Williams, R. (n.d.). Poly-e-Lysine or Mel4 Antimicrobial Surface Modification on a Novel Peptide Hydrogel Bandage Contact Lens. Advanced Materials Interfaces. doi:10.1002/admi.202001232
Antimicrobial Activity of Poly-epsilon-lysine Peptide Hydrogels Against Pseudomonas aeruginosa (Journal article)
Kennedy, S. M., Deshpande, P., Gallagher, A. G., Horsburgh, M. J., Allison, H. E., Kaye, S. B., . . . Williams, R. L. (2020). Antimicrobial Activity of Poly-epsilon-lysine Peptide Hydrogels Against Pseudomonas aeruginosa. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 61(10). doi:10.1167/iovs.61.10.18
In vitro and computational modelling of drug delivery across the outer blood-retinal barrier (Journal article)
Davies, A. E., Williams, R. L., Lugano, G., Pop, S. R., & Kearns, V. R. (2020). In vitro and computational modelling of drug delivery across the outer blood-retinal barrier. INTERFACE FOCUS, 10(2). doi:10.1098/rsfs.2019.0132
Mass Spectrometry Reveals alpha-2-HS-Glycoprotein as a Key Early Extracellular Matrix Protein for Conjunctival Cells (Journal article)
Makuloluwa, A. K., Stewart, R. M. K., Kaye, S. B., Williams, R. L., & Hamill, K. J. (2020). Mass Spectrometry Reveals alpha-2-HS-Glycoprotein as a Key Early Extracellular Matrix Protein for Conjunctival Cells. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 61(3). doi:10.1167/iovs.61.3.44
CRISPR-Cas9-mediated labelling of the C-terminus of human laminin ß1 leads to secretion inhibition. (Journal article)
Shaw, L., Williams, R. L., & Hamill, K. J. (2020). CRISPR-Cas9-mediated labelling of the C-terminus of human laminin ß1 leads to secretion inhibition.. BMC research notes, 13(1), 90. doi:10.1186/s13104-020-04956-z
2019
Antimicrobial nitric oxide releasing contact lens gels for the treatment of microbial keratitis. (Journal article)
Aveyard, J. L., Deller, R. C., Lace, R., Williams, R. L., Kaye, S. B., Kolegraff, K. N., . . . D'Sa, R. A. (2019). Antimicrobial nitric oxide releasing contact lens gels for the treatment of microbial keratitis.. ACS applied materials & interfaces. doi:10.1021/acsami.9b13958
Poly-epsilon-lysine based hydrogels as synthetic substrates for the expansion of corneal endothelial cells for transplantation (Journal article)
Kennedy, S., Lace, R., Carserides, C., Gallagher, A. G., Wellings, D. A., Williams, R. L., & Levis, H. J. (2019). Poly-epsilon-lysine based hydrogels as synthetic substrates for the expansion of corneal endothelial cells for transplantation. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 30(9). doi:10.1007/s10856-019-6303-1
Laminin beta 1 with C-terminal Dendra2 fluorescent protein tag is inefficiently secreted from lung adenocarcinoma cells in culture (Conference Paper)
Shaw, L., Williams, R. L., & Hamill, K. J. (2019). Laminin beta 1 with C-terminal Dendra2 fluorescent protein tag is inefficiently secreted from lung adenocarcinoma cells in culture. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A35). Retrieved from http://gateway.webofknowledge.com/
Plasma Polymer Coatings To Direct the Differentiation of Mouse Kidney-Derived Stem Cells into Podocyte and Proximal Tubule-like Cells (Journal article)
Hopp, I., MacGregor, M. N., Doherty, K., Visalakshan, R. M., Vasilev, K., Williams, R., & Murray, P. (2019). Plasma Polymer Coatings To Direct the Differentiation of Mouse Kidney-Derived Stem Cells into Podocyte and Proximal Tubule-like Cells. ACS Biomaterials Science and Engineering, 5(6), 2834-2845. doi:10.1021/acsbiomaterials.9b00299
Learning Active Contour Models for Medical Image Segmentation (Conference Paper)
Chen, X., Williams, B. M., Vallabhaneni, S. R., Czanner, G., Williams, R., & Zheng, Y. (2019). Learning Active Contour Models for Medical Image Segmentation. In 2019 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) (pp. 11624-11632). Long Beach, CA, USA: IEEE. doi:10.1109/cvpr.2019.01190
INCORPORATION OF ENDOTHELIAL COLONY FORMING CELLS INTO AN IN VITRO HUMAN PRIMARY CO-CULTURE MODEL OF DIABETIC RETINOPATHY (Conference Paper)
Eyre, J. J., Bosworth, L. A., Williams, R. L., & Levis, H. J. (2019). INCORPORATION OF ENDOTHELIAL COLONY FORMING CELLS INTO AN IN VITRO HUMAN PRIMARY CO-CULTURE MODEL OF DIABETIC RETINOPATHY. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 29 (pp. NP21-NP22). Retrieved from http://gateway.webofknowledge.com/
Plasma Polymerisation Using Helium Atmospheric-Pressure Plasma Jet with Heptylamine Monomer (Journal article)
Doherty, K. G., Oh, J. -S., Unsworth, P., Sheridan, C. M., Weightman, P., Bradley, J., & Williams, R. L. (2019). Plasma Polymerisation Using Helium Atmospheric-Pressure Plasma Jet with Heptylamine Monomer. Plasma Processes and Polymers, 16(4). doi:10.1002/ppap.201800185
Biomaterials in Ophthalmology (Chapter)
Williams, R. L., Levis, H. J., Lace, R., Doherty, K. G., Kennedy, S. M., & Kearns, V. R. (2019). Biomaterials in Ophthalmology. In Encyclopedia of Biomedical Engineering (pp. 289-300). Elsevier. doi:10.1016/b978-0-12-801238-3.11034-7
2018
Biomaterials for Regenerative Medicine Approaches for the Anterior Segment of the Eye (Journal article)
Williams, R., Lace, R., Kennedy, S., Doherty, K., & Levis, H. (2018). Biomaterials for Regenerative Medicine Approaches for the Anterior Segment of the Eye. ADVANCED HEALTHCARE MATERIALS, 7(10). doi:10.1002/adhm.201701328
Developing Regenerative Medicine Strategies for Diabetic Retinopathy using Human Retinal Endothelial Cells (Conference Paper)
Eyre, J. J., Williams, R. L., Bosworth, L. A., & Levis, H. J. (2018). Developing Regenerative Medicine Strategies for Diabetic Retinopathy using Human Retinal Endothelial Cells. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 28 (pp. 12). Retrieved from http://gateway.webofknowledge.com/
Modulated release from implantable ocular silicone oil tamponade drug reservoirs (Journal article)
Cauldbeck, H., Le Hellaye, M., McDonald, T., Long, M., Williams, R., Rannard, S. P., & Kearns, V. R. (2018). Modulated release from implantable ocular silicone oil tamponade drug reservoirs. Journal of Polymer Science. Part A, Polymer Chemistry, 56(8), 938-946. doi:10.1002/pola.28973
Development of decellularized conjunctiva as a substrate for the ex vivo expansion of conjunctival epithelium (Journal article)
Kasbekar, S., Kaye, S. B., Williams, R. L., Stewart, R. M. K., Leow-Dyke, S., & Rooney, P. (2018). Development of decellularized conjunctiva as a substrate for the ex vivo expansion of conjunctival epithelium. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 12(2), E973-E982. doi:10.1002/term.2419
2017
The Role of Controlled Surface Topography and Chemistry on Mouse Embryonic Stem Cell Attachment, Growth and Self-Renewal (Journal article)
Macgregor, M., Williams, R., Downes, J., Bachhuka, A., & Vasilev, K. (2017). The Role of Controlled Surface Topography and Chemistry on Mouse Embryonic Stem Cell Attachment, Growth and Self-Renewal. MATERIALS, 10(9). doi:10.3390/ma10091081
Development of a Poly-e-lysine Contact Lens as a Drug Delivery Device for the Treatment of Fungal Keratitis (Journal article)
Gallagher, A. G., McLean, K., Stewart, R. M. K., Wellings, D., Allison, H. E., & Williams, R. L. (2017). Development of a Poly-e-lysine Contact Lens as a Drug Delivery Device for the Treatment of Fungal Keratitis. Investigative Ophthalmology and Visual Science, 58(11), 4499-4505. doi:10.1167/iovs.17-22301
Development of a Poly-epsilon-lysine Contact Lens for Drug Delivery in the Management of Fungal Keratitis (Conference Paper)
McLean, K., Gallagher, A. G., Stewart, R. M. K., Wellings, D. A., Allison, H. E., & Williams, R. (2017). Development of a Poly-epsilon-lysine Contact Lens for Drug Delivery in the Management of Fungal Keratitis. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from http://gateway.webofknowledge.com/
The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry (Journal article)
Kearns, V. R., Tasker, J., Zhuola., Akhtar, R., Bachhuka, A., Vasilev, K., . . . Williams, R. (2017). The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry. Journal of Materials Science: Materials in Medicine, 28. doi:10.1007/s10856-017-5926-3
Towards better characterization and quantification of emulsification of silicone oil in vitro (Journal article)
Chan, Y. K., Czanner, G., Shum, H. C., Williams, R. L., Cheung, N., & Wong, D. (2017). Towards better characterization and quantification of emulsification of silicone oil in vitro. Acta Ophthalmologica, 95(5), e385-e392. doi:10.1111/aos.13258
2016
Controlling drug release from non-aqueous environments: Moderating delivery from ocular silicone oil drug reservoirs to combat proliferative vitreoretinopathy (Journal article)
Cauldbeck, H., Le Hellaye, M., Long, M., Kennedy, S. M., Williams, R. L., Kearns, V. R., & Rannard, S. P. (2016). Controlling drug release from non-aqueous environments: Moderating delivery from ocular silicone oil drug reservoirs to combat proliferative vitreoretinopathy. Journal of Controlled Release, 244(Part A), 41-51. doi:10.1016/j.jconrel.2016.11.010
A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens (Journal article)
Gallagher, A. G., Alorabi, J. A., Wellings, D. A., Lace, R., Horsburgh, M. J., & Williams, R. L. (2016). A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens. Advanced Healthcare Materials, 5(16), 2013-2018. doi:10.1002/adhm.201600258
2015
Biomaterials for ocular reconstruction (Journal article)
Lace, R., Murray-Dunning, C., & Williams, R. (2015). Biomaterials for ocular reconstruction. JOURNAL OF MATERIALS SCIENCE, 50(4), 1523-1534. doi:10.1007/s10853-014-8707-0
Distal fixation forces of different endovascular limb extensions in an experimental porcine model (Journal article)
Shah, S., Jones, S. M., How, T. V., Williams, R. L., & Fisher, R. K. (2015). Distal fixation forces of different endovascular limb extensions in an experimental porcine model. BRITISH JOURNAL OF SURGERY, 102, 15. Retrieved from http://gateway.webofknowledge.com/
Haemodynamic Evidence that Large Iliac Arteries Increase the Risk of Limb Migration following Endovascular Aneurysm Repair (Conference Paper)
Jones, S. M., England, A., Poole, R. J., Vallabhaneni, S. R., Brennan, J. A., McWilliams, R. G., . . . Fisher, R. K. (2015). Haemodynamic Evidence that Large Iliac Arteries Increase the Risk of Limb Migration following Endovascular Aneurysm Repair. In BRITISH JOURNAL OF SURGERY Vol. 102 (pp. 13-14). Retrieved from http://gateway.webofknowledge.com/
Development of emulsification resistant heavier-than-water tamponades using high molecular weight silicone oil polymers (Journal article)
Caramoy, A., Kearns, V. R., Chan, Y. K., Hagedorn, N., Poole, R. J., Wong, D., . . . Williams, R. L. (2015). Development of emulsification resistant heavier-than-water tamponades using high molecular weight silicone oil polymers. JOURNAL OF BIOMATERIALS APPLICATIONS, 30(2), 212-220. doi:10.1177/0885328215575623
2014
Flow Behavior of Heavy Silicone Oil During Eye Movements (Journal article)
Chan, Y. K., Williams, R. L., & Wong, D. (2014). Flow Behavior of Heavy Silicone Oil During Eye Movements. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 55(12), 8453-8457. doi:10.1167/iovs.14-15439
Fibrinogen adsorption and platelet adhesion to silica surfaces with stochastic nanotopography (Journal article)
Lord, M. S., Whitelock, J. M., Simmons, A., Williams, R. L., & Milthorpe, B. K. (2014). Fibrinogen adsorption and platelet adhesion to silica surfaces with stochastic nanotopography. BIOINTERPHASES, 9(4). doi:10.1116/1.4900993
Computational Fluid Dynamic (CFD) analysis of the distraction forces experienced by stent-grafts following fEVAR (Conference Paper)
Jones, S. M., Poole, R. J., How, T. V., Williams, R. L., McWilliams, R. G., Brennan, J. A., . . . Fisher, R. K. (2014). Computational Fluid Dynamic (CFD) analysis of the distraction forces experienced by stent-grafts following fEVAR. In BRITISH JOURNAL OF SURGERY Vol. 101 (pp. 2). Retrieved from http://gateway.webofknowledge.com/
Computational fluid dynamic analysis of the effect of morphologic features on distraction forces in fenestrated stent grafts (Journal article)
Jones, S. M., Poole, R. J., How, T. V., Williams, R. L., McWilliams, R. G., Brennan, J. A., . . . Fisher, R. K. (2014). Computational fluid dynamic analysis of the effect of morphologic features on distraction forces in fenestrated stent grafts. JOURNAL OF VASCULAR SURGERY, 60(6), 1648-U632. doi:10.1016/j.jvs.2014.08.077
2013
Novel Heavy Tamponade for Vitreoretinal Surgery (Journal article)
Williams, R. L., Kearns, V. R., Lo, A. C., Day, M., Garvey, M. J., Krishna, Y., . . . Wong, D. (2013). Novel Heavy Tamponade for Vitreoretinal Surgery. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 54(12), 7284-7292. doi:10.1167/iovs.13-11876
Polystyrene Surface Modification for Localized Cell Culture Using a Capillary Dielectric Barrier Discharge Atmospheric-Pressure Microplasma Jet (Journal article)
Doherty, K. G., Oh, J. -S., Unsworth, P., Bowfield, A., Sheridan, C. M., Weightman, P., . . . Williams, R. L. (2013). Polystyrene Surface Modification for Localized Cell Culture Using a Capillary Dielectric Barrier Discharge Atmospheric-Pressure Microplasma Jet. PLASMA PROCESSES AND POLYMERS, 10(11), 978-989. doi:10.1002/ppap.201300052
Characterization of the interface between adsorbed fibronectin and human embryonic stem cells (Journal article)
Kalaskar, D. M., Downes, J. E., Murray, P., Edgar, D. H., & Williams, R. L. (2013). Characterization of the interface between adsorbed fibronectin and human embryonic stem cells. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 10(83). doi:10.1098/rsif.2013.0139
Complications related to the tamponade agent: Emulsification of tamponade agents (Chapter)
Williams, R., & Stappler, T. (2013). Complications related to the tamponade agent: Emulsification of tamponade agents. In Complications of Vitreo-Retinal Surgery.
Induction of mesenchymal stem cell chondrogenesis by polyacrylate substrates (Journal article)
Glennon-Alty, L., Williams, R., Dixon, S., & Murray, P. (2013). Induction of mesenchymal stem cell chondrogenesis by polyacrylate substrates. ACTA BIOMATERIALIA, 9(4), 6041-6051. doi:10.1016/j.actbio.2012.12.007
The influence of high intensity terahertz radiation on mammalian cell adhesion, proliferation and differentiation (Journal article)
Williams, R., Schofield, A., Holder, G., Downes, J., Edgar, D., Harrison, P., . . . Weightman, P. (2013). The influence of high intensity terahertz radiation on mammalian cell adhesion, proliferation and differentiation. PHYSICS IN MEDICINE AND BIOLOGY, 58(2), 373-391. doi:10.1088/0031-9155/58/2/373
Degradative Effects of the Biological Environment on Metals and Ceramics (Chapter)
Williams, D. F., & Williams, R. L. (2013). Degradative Effects of the Biological Environment on Metals and Ceramics. In Biomaterials Science (pp. 728-738). Elsevier. doi:10.1016/b978-0-08-087780-8.00062-0
Guided gingival fibroblast attachment to titanium surfaces: an in vitro study (Journal article)
Kearns, V. R., Williams, R. L., Mirvakily, F., Doherty, P. J., & Martin, N. (2013). Guided gingival fibroblast attachment to titanium surfaces: an in vitro study. JOURNAL OF CLINICAL PERIODONTOLOGY, 40(1), 99-108. doi:10.1111/jcpe.12025
2012
Plasma polymer coatings to aid retinal pigment epithelial growth for transplantation in the treatment of age related macular degeneration (Journal article)
Kearns, V., Mistry, A., Mason, S., Krishna, Y., Sheridan, C., Short, R., & Williams, R. L. (2012). Plasma polymer coatings to aid retinal pigment epithelial growth for transplantation in the treatment of age related macular degeneration. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 23(8), 2013-2021. doi:10.1007/s10856-012-4675-6
Characteristics Of Rat Iris Pigment Epithelial Cells Cultured On Modified Expanded-polytetrafluroethylene (ePTFE) Substrates (Conference Paper)
Nian, S., Sheridan, C. M., Kearns, V., Williams, R., Wong, D., Vasillev, K., . . . Lai, W. W. (2012). Characteristics Of Rat Iris Pigment Epithelial Cells Cultured On Modified Expanded-polytetrafluroethylene (ePTFE) Substrates. In ARVO 2012 Vol. 53 (pp. 5840). Fort Lauderdale: IOVS.
GROWTH OF PORCINE IRIS PIGMENTED EPITHELIAL CELLS ON SUBSTRATES FOR THE TREATMENT OF AGE RELATED MACULAR DEGENERATION (AMD) (Conference Paper)
Alias, E., Kearns, V., Harrison, I., Sheridan, C., & Williams, R. (2012). GROWTH OF PORCINE IRIS PIGMENTED EPITHELIAL CELLS ON SUBSTRATES FOR THE TREATMENT OF AGE RELATED MACULAR DEGENERATION (AMD). In XX Biennial Meeting of the International Society for Eye Research (pp. 261). Berlin: ISER. Retrieved from http://www.iser.org/files/2012_abstracts.pdf
QUANTIFICATION OF RETINAL THICKNESS FOLLOWING IMPLANTATION OF ACELLULAR SURFACE-MODIFIED EXPANDED POLYTETRAFLUOROETHYLENE (EPTFE) IN A RABBIT MODEL USING SD-OCT AND HISTOLOGY (Conference Paper)
Kearns, V., Eter, N., Liu, Z., Brinken, R., Somboonthanakij, S., Wongsawag, W., . . . Stanzel, B. V. (2012). QUANTIFICATION OF RETINAL THICKNESS FOLLOWING IMPLANTATION OF ACELLULAR SURFACE-MODIFIED EXPANDED POLYTETRAFLUOROETHYLENE (EPTFE) IN A RABBIT MODEL USING SD-OCT AND HISTOLOGY. In XX Biennial Meeting of the International Society for Eye Research (pp. 287). Berlin: ISER. Retrieved from http://www.iser.org/files/2012_abstracts.pdf
QUANTIFICATION OF RETINAL THICKNESS FOLLOWING IMPLANTATION OF ACELLULAR ULTRATHIN POLYESTER CELL CARRIERS IN A RABBIT MODEL USING SD-OCT AND HISTOLOGY (Conference Paper)
Stanzel, B., Kearns, V., Eter, N., Liu, Z., Brinken, R., Somboonthanakij, S., . . . Sheridan, C. (2012). QUANTIFICATION OF RETINAL THICKNESS FOLLOWING IMPLANTATION OF ACELLULAR ULTRATHIN POLYESTER CELL CARRIERS IN A RABBIT MODEL USING SD-OCT AND HISTOLOGY. In XX Biennial Meeting of the International Society for Eye Research (pp. 266). Berlin: ISER. Retrieved from http://www.iser.org/files/2012_abstracts.pdf
2011
Emulsification of Silicone Oil and Eye Movements (Journal article)
Chan, Y. K., Ng, C. O., Knox, P. C., Garvey, M. J., Williams, R. L., & Wong, D. (2011). Emulsification of Silicone Oil and Eye Movements. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 52(13), 9721-9727. doi:10.1167/iovs.11-8586
Atmospheric pressure micro-plasma jet technology for influencing cell-surface interactions (Conference Paper)
Doherty, K., Oh, J. S., Sheridan, C., Williams, R., & Bradley, J. W. (2011). Atmospheric pressure micro-plasma jet technology for influencing cell-surface interactions. In 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials.
Glycosaminoglycan coatings for intraocular lenses as a potential to inhibit posterior capsule opacification (Conference Paper)
Lace, R., Rhodes, A., Onis, S., Sandhu, S., Luthra, A., Sheridan, C., & Williams, R. (2011). Glycosaminoglycan coatings for intraocular lenses as a potential to inhibit posterior capsule opacification. In 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials.
The influence of surface chemistry and roughness on ECM production on bruch's membrane prostheses (Conference Paper)
Kearns, V., Vasilev, K., Sheridan, C., & Williams, R. (2011). The influence of surface chemistry and roughness on ECM production on bruch's membrane prostheses. In 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials.
The status of the alice r&d facility at stfc daresbury laboratory (Conference Paper)
Jackson, F., Angal-Kalinin, D., Bate, B., Buckley, R., Buckley, S., Clarke, J., . . . Wolski, A. (2011). The status of the alice r&d facility at stfc daresbury laboratory. In IPAC 2011 - 2nd International Particle Accelerator Conference (pp. 934-936).
Ocular epithelial transplantation: current uses and future potential (Journal article)
Mason, S. L., Stewart, R. M. K., Kearns, V. R., Williams, R. L., & Sheridan, C. M. (2011). Ocular epithelial transplantation: current uses and future potential. REGENERATIVE MEDICINE, 6(6), 767-782. doi:10.2217/RME.11.94
The use of reflection anisotropy spectroscopy to assess the alignment of collagen (Journal article)
Schofield, A. L., Smith, C. I., Kearns, V. R., Martin, D. S., Farrell, T., Weightman, P., & Williams, R. L. (2011). The use of reflection anisotropy spectroscopy to assess the alignment of collagen. JOURNAL OF PHYSICS D-APPLIED PHYSICS, 44(33). doi:10.1088/0022-3727/44/33/335302
The impact of axial length on retinal tamponade for gas, silicone oil, and heavy silicone oil, using an in vitro model (Journal article)
Hillier, R. J., Stappler, T., Williams, R. L., Turner, G. S., & Wong, D. (2011). The impact of axial length on retinal tamponade for gas, silicone oil, and heavy silicone oil, using an in vitro model. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 249(5), 671-675. doi:10.1007/s00417-010-1579-3
Expanded polytetrafluoroethylene as a substrate for retinal pigment epithelial cell growth and transplantation in age-related macular degeneration (Journal article)
Krishna, Y., Sheridan, C., Kent, D., Kearns, V., Grierson, I., & Williams, R. (2011). Expanded polytetrafluoroethylene as a substrate for retinal pigment epithelial cell growth and transplantation in age-related macular degeneration. BRITISH JOURNAL OF OPHTHALMOLOGY, 95(4), 569-573. doi:10.1136/bjo.2009.169953
Injectability of silicone oil-based tamponade agents (Journal article)
Williams, R. L., Day, M. J., Garvey, M. J., Morphis, G., Irigoyen, C., Wong, D., & Stappler, T. (2011). Injectability of silicone oil-based tamponade agents. BRITISH JOURNAL OF OPHTHALMOLOGY, 95(2), 273-276. doi:10.1136/bjo.2010.192344
Comparison of Growth and Monolayer Formation of Primary Bovine Rpe and Ipe on Polyurethane (Pu) Membranes. (Conference Paper)
Alias, E., Kearns, V. R., Harrison, I. M., Sheridan, C. M., & Williams, R. L. (2011). Comparison of Growth and Monolayer Formation of Primary Bovine Rpe and Ipe on Polyurethane (Pu) Membranes.. In TERMIS-EU (pp. 342). .: TERMIS.
Optimisation of primary cell culture conditions for retinal and iris pigment epithelial cell transplantation on artificial substrates (Conference Paper)
Kearns, V., Vasilev, K., Nian, S., Sheridan, C., & Williams, R. L. (2011). Optimisation of primary cell culture conditions for retinal and iris pigment epithelial cell transplantation on artificial substrates. In TERMIS-EU (pp. .). Granada, Spain: TERMIS.
Preface (Book)
Williams, R. (2011). Preface. Elsevier. doi:10.1016/b978-1-84569-640-5.50019-1
Surface Modification of biomaterials; Methods, analysis and applications (Book)
Williams, R. (Ed.) (2011). Surface Modification of biomaterials; Methods, analysis and applications. Cambridge: Woodhead Publishing Ltd.
Surface modification of biomaterials (Book)
Williams, R. (2011). Surface modification of biomaterials. Woodhead Publishing Limited. doi:10.1533/9780857090768
Surface modified expanded-polytetrafluoroethylene (ePTFE) substrates for retinal pigment epithelial growth and implantation (Journal article)
Kearns, V. R., Nian, S., Vasilev, K., Sheridan, C., & Williams, R. L. (2011). Surface modified expanded-polytetrafluoroethylene (ePTFE) substrates for retinal pigment epithelial growth and implantation. European Cells and Materials, 22(SUPPL.2), 54.
2010
Recent developments on ALICE (Accelerators and lasers in combined experiments) at Daresbury Laboratory (Conference Paper)
Saveliev, Y., Bate, B., Buckley, R., Buckley, S., Clarke, J., Corlett, P., . . . Powers, T. (2010). Recent developments on ALICE (Accelerators and lasers in combined experiments) at Daresbury Laboratory. In IPAC 2010 - 1st International Particle Accelerator Conference (pp. 2350-2352).
Friction transfer of polytetrafluoroethylene (PTFE) to produce nanoscale features and influence cellular response in vitro (Journal article)
Kearns, V. R., Doherty, P. J., Beamson, G., Martin, N., & Williams, R. L. (2010). Friction transfer of polytetrafluoroethylene (PTFE) to produce nanoscale features and influence cellular response in vitro. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 21(7), 2213-2226. doi:10.1007/s10856-010-4081-x
Reflection anisotropy spectra of polydimethylsiloxane under a range of mechanically applied stress (Journal article)
Farrell, T., Smith, C. I., Schofield, A. L., Williams, R. L., & Weightman, P. (2010). Reflection anisotropy spectra of polydimethylsiloxane under a range of mechanically applied stress. JOURNAL OF PHYSICS D-APPLIED PHYSICS, 43(24). doi:10.1088/0022-3727/43/24/245301
MECHANICAL AND BIOLOGICAL PROPERTIES OF TITANIUM SYNTACTIC FOAMS (Conference Paper)
Xue, X. B., Zhao, Y. Y., Kearns, V., Williams, R. L., & TMS. (2010). MECHANICAL AND BIOLOGICAL PROPERTIES OF TITANIUM SYNTACTIC FOAMS. In TMS 2010 139TH ANNUAL MEETING & EXHIBITION - SUPPLEMENTAL PROCEEDINGS, VOL 2: MATERIALS CHARACTERIZATION, COMPUTATION AND MODELING AND ENERGY (pp. 129-+). Retrieved from http://gateway.webofknowledge.com/
Effect of VEGF and Anti-VEGF Compounds on Retinal Pigment Epithelium Permeability: An in vitro Study (Conference Paper)
Campa, C., Kearns, V., Sheridan, C., Williams, R., Grierson, I., & Harding, S. P. (2010). Effect of VEGF and Anti-VEGF Compounds on Retinal Pigment Epithelium Permeability: An in vitro Study. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 51. Retrieved from http://gateway.webofknowledge.com/
F4H5: a novel substance for the removal of silicone oil from intraocular lenses (Journal article)
Stappler, T., Williams, R., & Wong, D. (2010). F4H5: a novel substance for the removal of silicone oil from intraocular lenses. BRITISH JOURNAL OF OPHTHALMOLOGY, 94(3), 364-367. doi:10.1136/bjo.2009.161489
INCREASING THE EXTENSIONAL VISCOSITY OF SILICONE OIL REDUCES THE TENDENCY FOR EMULSIFICATION (Journal article)
Williams, R. L., Day, M., Garvey, M. J., English, R., & Wong, D. (2010). INCREASING THE EXTENSIONAL VISCOSITY OF SILICONE OIL REDUCES THE TENDENCY FOR EMULSIFICATION. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 30(2), 300-304. doi:10.1097/IAE.0b013e3181babe0c
Atmospheric-Pressure Microplasma-Jet Modified Polystyrene Surfaces as Substrates for Epithelial Cell Growth (Journal article)
Oh, J. S., Bradley, J. W., Doherty, K. G., Sheridan, C. M., Williams, R. L., Bowfield, A., . . . Weightman, P. (2010). Atmospheric-Pressure Microplasma-Jet Modified Polystyrene Surfaces as Substrates for Epithelial Cell Growth. AVS 57th International Symposium and Exhibition, 57, PS2-MoA11. Retrieved from http://www2.avs.org/symposium2010/Papers/Paper_PS2-MoA11.html
Comparison of growth and monolayer formation of primary bovine RPE and IPE on polyurethane (PU) membranes (Conference Paper)
Alias, E., Kearns, V. R., Harrison, I. M., Dixon, S. A., Laws, F. A., Sheridan, C. M., & Williams, R. L. (2010). Comparison of growth and monolayer formation of primary bovine RPE and IPE on polyurethane (PU) membranes. In TERMIS-EU (pp. x). Galway, Ireland: TERMIS.
Evaluation of Basement Membrane Formation on Bruch's Membrane Implants (Conference Paper)
Kearns, V. R., Vasilev, K., Sheridan, C. M., & Williams, R. L. (2010). Evaluation of Basement Membrane Formation on Bruch's Membrane Implants. In TERMIS-EU (pp. x). Galway, Ireland: TERMIS.
Novel Polymeric Coatings with the Potential to Control In-stent Restenosis - An In Vitro Study (Journal article)
Nickson, C. M., Doherty, P. J., & Williams, R. L. (2010). Novel Polymeric Coatings with the Potential to Control In-stent Restenosis - An In Vitro Study. JOURNAL OF BIOMATERIALS APPLICATIONS, 24(5), 437-452. doi:10.1177/0885328208099338
Surface Modified Expanded-polytetrafluoroethylene (ePTFE) Substrates for Retinal Pigment Epithelial Growth and Implantation (Conference Paper)
Kearns, V. R., Nian, S., Vasilev, K., Sheridan, C. M., & Williams, R. L. (2010). Surface Modified Expanded-polytetrafluoroethylene (ePTFE) Substrates for Retinal Pigment Epithelial Growth and Implantation. In TCES (Tissue and Cell Engineering Society) 2010 (pp. x). Manchester, UK: TCES.
2009
Ophthalmic Biomaterials (Chapter)
Williams, R. L., & Wong, D. (2009). Ophthalmic Biomaterials. In Biomedical Materials (pp. 327-347). Springer US. doi:10.1007/978-0-387-84872-3_12
Drug delivery systems for the eye (Journal article)
Kearns, V. R., & Williams, R. L. (2009). Drug delivery systems for the eye. EXPERT REVIEW OF MEDICAL DEVICES, 6(3), 277-290. doi:10.1586/ERD.09.4
Angle resolved XPS characterization of cationic polyacrylamides (Journal article)
Zekonyte, J., Williams, R. L., Beamson, G., & Weightman, P. (2009). Angle resolved XPS characterization of cationic polyacrylamides. SURFACE AND INTERFACE ANALYSIS, 41(4), 316-323. doi:10.1002/sia.3025
Drug-Device Combination Products for Ocular Applications (Chapter)
Williams, R. L., & Kearns, V. R. (2009). Drug-Device Combination Products for Ocular Applications. In A. Lewis (Ed.), Drug Device Combination Products (pp. In Press). Cambridge, UK: Woodhead Publishing Limited.
Drug–device combination products for ocular applications (Chapter)
WILLIAMS, R. L., & KEARNS, V. R. (2010). Drug–device combination products for ocular applications. In Drug-Device Combination Products (pp. 311-338). Elsevier. doi:10.1533/9781845697488.2.311
Replacement of the RPE monolayer (Journal article)
Sheridan, C. M., Mason, S., Pattwell, D. M., Kent, D., Grierson, I., & Williams, R. (2009). Replacement of the RPE monolayer. EYE, 23(10), 1910-1915. doi:10.1038/eye.2008.420
•Calcium depletion alters tenocyte surface adhesion ability: possible role of ca2+ channel blockers in tendon healing. (Journal article)
Kamarul, T., Roebuck, M. M., Williams, R. L., & Frostick, S. P. (2009). •Calcium depletion alters tenocyte surface adhesion ability: possible role of ca2+ channel blockers in tendon healing.. British J Orthopaedics, 2010, i-ii.
•Tenocyte alignment is dependant upon cell density and tensional loading. (Journal article)
Kamarul, T., Roebuck, M. M., Williams, R. L., & Frostick, S. P. (2009). •Tenocyte alignment is dependant upon cell density and tensional loading.. European Cell and Materials Journal, 2010, i-ii.
•The effects of cyclical loading on tendon fibroblast metabolism in vitro (Journal article)
Kamarul, T., Roebuck, M. M., Williams, R. L., & Frostick, S. P. (2009). •The effects of cyclical loading on tendon fibroblast metabolism in vitro. Orthopaedic Research Society, 2010, i-ii.
2008
A novel technique for probing the anisotropic structure of tendon (Conference Paper)
Smith, C. I., Mansley, C. P., Weightman, P., & Williams, R. L. (2008). A novel technique for probing the anisotropic structure of tendon. In 8th World Biomaterials Congress 2008 Vol. 3 (pp. 1233).
Human endothelial cell response to a novel polymeric stent coating (Conference Paper)
Nickson, C. M., Dixon, S., Laws, F., Harrison, I., & Williams, R. L. (2008). Human endothelial cell response to a novel polymeric stent coating. In 8th World Biomaterials Congress 2008 Vol. 4 (pp. 2155).
The effect of surface chemistry and topography on the orientation of cells and collagen (Conference Paper)
Kearns, V. R., Doherty, P. J., Martin, N., & Williams, R. L. (2008). The effect of surface chemistry and topography on the orientation of cells and collagen. In 8th World Biomaterials Congress 2008 Vol. 3 (pp. 1158).
Shear and extensional rheometry of PDMS tamponade agents used in vitroretinal surgery (Conference Paper)
Day, M., Blanchard, R. -L., English, R., Dobbie, T., Williams, R., Garvey, M., & Wong, D. (2008). Shear and extensional rheometry of PDMS tamponade agents used in vitroretinal surgery. In XVTH INTERNATIONAL CONGRESS ON RHEOLOGY - THE SOCIETY OF RHEOLOGY 80TH ANNUAL MEETING, PTS 1 AND 2 Vol. 1027 (pp. 1411-+). Retrieved from http://gateway.webofknowledge.com/
Tenocyte alignment is dependant upon cell density and tensional loading (Conference Paper)
Kamarul, T., Roebuck, M. M., Williams, R. L., & Frostick, S. P. (2008). Tenocyte alignment is dependant upon cell density and tensional loading. In European Cells and Materials Vol. 16 (pp. 62).
A guide to the removal of heavy silicone oil (Journal article)
Stappler, T., Williams, R., Gibran, S. K., Liazos, E., & Wong, D. (2008). A guide to the removal of heavy silicone oil. BRITISH JOURNAL OF OPHTHALMOLOGY, 92(6), 844-847. doi:10.1136/bjo.2007.134569
Synthesis and Properties of Functional Poly(vinylpyrrolidinone) Hydrogels for Drug Delivery (Conference Paper)
Smith, L. E., Collins, S., Liu, Z., Mac Neil, S., Williams, R., & Rimmer, S. (2008). Synthesis and Properties of Functional Poly(vinylpyrrolidinone) Hydrogels for Drug Delivery. In POLYMERS FOR BIOMEDICAL APPLICATIONS Vol. 977 (pp. 196-203). Retrieved from http://gateway.webofknowledge.com/
F4H5 -A novel substance for the removal of silicone oil from intraocular lenses. (Journal article)
Stappler, T., Williams, R., & Wong, D. (2008). F4H5 -A novel substance for the removal of silicone oil from intraocular lenses.. Invest. Ophthalmol. Vis. Sci., 49, 5602.
Manufacturing a nanometre scale surface topography with varying surface chemistry to assess the combined effect on cell behaviour (Journal article)
Cousins, B. G., Zekonyte, J., Doherty, P. J., Garvey, M. J., & Williams, R. L. (2008). Manufacturing a nanometre scale surface topography with varying surface chemistry to assess the combined effect on cell behaviour. International Journal of Nano and Biomaterials, 1(3), 320. doi:10.1504/ijnbm.2008.016878
Shear and extensional rheometry of PDMS tamponade agents used in vitroretinal surgery (Journal article)
Day, M., Blanchard, R. -L., English, R., Dobbie, T., Williams, R., Garvey, M., & Wong, D. (2008). Shear and extensional rheometry of PDMS tamponade agents used in vitroretinal surgery. XVTH INTERNATIONAL CONGRESS ON RHEOLOGY - THE SOCIETY OF RHEOLOGY 80TH ANNUAL MEETING, PTS 1 AND 2, 1027, 1411-1413.
Tenocyte alignment is dependent upon cell density and tensional loading. (Journal article)
Kamarul, T., Roebuck, M. M., Williams, R. L., & Frostick, S. P. (2008). Tenocyte alignment is dependent upon cell density and tensional loading.. European Cell and Mater, 16((suppl), 62.
UK Society for Biomaterials Annual Conference: Abstracts 2008 (Book)
Williams, R. L., Kearns, V. R., & Nickson, C. M. (Eds.) (2008). UK Society for Biomaterials Annual Conference: Abstracts 2008. Liverpool, UK: UK Society for Biomaterials.
2007
Changes in the electronic structure of silicone rubber surfaces induced by oxygen plasma treatment (Journal article)
Haines, S. R., Beamson, G., Williams, R. L., & Weightman, P. (2007). Changes in the electronic structure of silicone rubber surfaces induced by oxygen plasma treatment. SURFACE AND INTERFACE ANALYSIS, 39(12-13), 942-947. doi:10.1002/sia.2646
Improvements in Alzheimer's disease diagnosis using principal component analysis (PCA) in combination with Raman spectroscopy (Conference Paper)
Archer, J. K. J., Sudworth, C. D., Williams, R., How, T., Stone, N., Mann, D., & Black, R. A. (2007). Improvements in Alzheimer's disease diagnosis using principal component analysis (PCA) in combination with Raman spectroscopy. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE Vol. 6628.
The effect of gas plasma modification on platelet and contact phase activation processes (Journal article)
Rhodes, N. P., Wilson, D. J., & Williams, R. L. (2007). The effect of gas plasma modification on platelet and contact phase activation processes. BIOMATERIALS, 28(31), 4561-4570. doi:10.1016/j.biomaterials.2007.07.008
Transplantation in the treatment of age-related macular degeneration: past, present and future directions (Journal article)
Sheridan, C., Krishna, Y., Williams, R., Mason, S., Wong, D., Heimann, H., . . . Grierson, I. (2007). Transplantation in the treatment of age-related macular degeneration: past, present and future directions. Expert Review of Ophthalmology, 2(3), 497-511. doi:10.1586/17469899.2.3.497
Does the surface property of a disposable applanation tonometer account for its underestimation of intraocular pressure when compared with the Goldmann tonometer? (Journal article)
Osborne, S. F., Williams, R., Batterbury, M., & Wong, D. (2007). Does the surface property of a disposable applanation tonometer account for its underestimation of intraocular pressure when compared with the Goldmann tonometer?. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 245(4), 555-559. doi:10.1007/s00417-006-0380-9
Effects of a nanoparticulate silica substrate on cell attachment of Candida albicans (Journal article)
Cousins, B. G., Allison, H. E., Doherty, P. J., Edwards, C., Garvey, M. J., Martin, D. S., & Williams, R. L. (2007). Effects of a nanoparticulate silica substrate on cell attachment of Candida albicans. JOURNAL OF APPLIED MICROBIOLOGY, 102(3), 757-765. doi:10.1111/j.1365-2672.2006.03124.x
Polydimethylsiloxane as a substrate for retinal pigment epithelial cell growth (Journal article)
Krishna, Y., Sheridan, C. M., Kent, D. L., Grierson, I., & Williams, R. L. (2007). Polydimethylsiloxane as a substrate for retinal pigment epithelial cell growth. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 80A(3), 669-678. doi:10.1002/jbm.a.30953
Improvements in alzheimer's disease diagnosis using principal component analysis (PCA) in combination with raman spectroscopy (Conference Paper)
Archer, J. K. J., Sudworth, C. D., Williams, R., How, T., Stone, N., Mann, D., & Black, R. A. (2007). Improvements in alzheimer's disease diagnosis using principal component analysis (PCA) in combination with raman spectroscopy. In Optics InfoBase Conference Papers.
2006
The effect of silica nanoparticulate coatings on serum protein adsorption and cellular response (Journal article)
Lord, M. S., Cousins, B. G., Doherty, P. J., Whitelock, J. M., Simmons, A., Williams, R. L., & Milthorpe, B. K. (2006). The effect of silica nanoparticulate coatings on serum protein adsorption and cellular response. BIOMATERIALS, 27(28), 4856-4862. doi:10.1016/j.biomaterials.2006.05.037
Modification of the surface properties of a lens material to influence posterior capsular opacification (Journal article)
Yuen, C., Williams, R., Batterbury, M., & Grierson, I. (2006). Modification of the surface properties of a lens material to influence posterior capsular opacification. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 34(6), 568-574. doi:10.1111/j.1442-9071.2006.01278.x
Reflection anisotropy spectroscopy study of the adsorption of sulfur-containing amino acids at the Au(110)/electrolyte interface (Journal article)
LeParc, R., Smith, C. I., Cuquerella, M. C., Williams, R. L., Fernig, D. G., Edwards, C., . . . Weightman, P. (2006). Reflection anisotropy spectroscopy study of the adsorption of sulfur-containing amino acids at the Au(110)/electrolyte interface. LANGMUIR, 22(7), 3413-3420. doi:10.1021/la052584u
2005
Polyurethanes as potential substrates for sub-retinal retinal pigment epithelial cell transplantation (Journal article)
Williams, R. L., Krishna, Y., Dixon, S., Haridas, A., Grierson, I., & Sheridan, C. (2005). Polyurethanes as potential substrates for sub-retinal retinal pigment epithelial cell transplantation. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 16(12), 1087-1092. doi:10.1007/s10856-005-4710-y
Sialin, an anion transporter defective in sialic acid storage diseases, shows highly variable expression in adult mouse brain, and is developmentally regulated. (Journal article)
Yarovaya, N., Schot, R., Fodero, L., McMahon, M., Mahoney, A., Williams, R., . . . Venter, D. J. (2005). Sialin, an anion transporter defective in sialic acid storage diseases, shows highly variable expression in adult mouse brain, and is developmentally regulated.. Neurobiology of disease, 19(3), 351-365. doi:10.1016/j.nbd.2004.12.020
What pressure is exerted on the retina by heavy tamponade agents? (Journal article)
Wong, D., Williams, R., Stappler, T., & Groenewald, C. (2005). What pressure is exerted on the retina by heavy tamponade agents?. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 243(5), 474-477. doi:10.1007/s00417-004-1047-z
2004
Stability of plasma-treated silicone rubber and its influence on the interfacial aspects of blood compatibility (Journal article)
Williams, R. L., Wilson, D. J., & Rhodes, N. P. (2004). Stability of plasma-treated silicone rubber and its influence on the interfacial aspects of blood compatibility. BIOMATERIALS, 25(19), 4659-4673. doi:10.1016/j.biomaterials.2003.12.010
Tamponade efficiency of perfluorohexyloctane and silicone oil solutions in a model eye chamber (Journal article)
Wetterqvist, C., Wong, D., Williams, R., Stappler, T., Herbert, E., & Freeburn, S. (2004). Tamponade efficiency of perfluorohexyloctane and silicone oil solutions in a model eye chamber. BRITISH JOURNAL OF OPHTHALMOLOGY, 88(5), 692-696. doi:10.1136/bjo.2003.024737
The effect of silica nanoparticulate coatings on cellular response (Journal article)
Cousins, B. G., Doherty, P. J., Williams, R. L., Fink, J., & Garvey, M. J. (2004). The effect of silica nanoparticulate coatings on cellular response. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 15(4), 355-359. doi:10.1023/B:JMSM.0000021101.64938.b3
Tamponade properties of double-filling with perfluorohexyloctane and silicone oil in a model eye chamber (Journal article)
Herbert, E., Stappler, T., Wetterqvist, C., Williams, R., & Wong, D. (2004). Tamponade properties of double-filling with perfluorohexyloctane and silicone oil in a model eye chamber. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 242(3), 250-254. doi:10.1007/s00417-003-0830-6
A sinking filling: The use of a model eye chamber to study the behaviour of tamponade agents (Journal article)
Wong, D., Stappler, T., & Williams, R. (2004). A sinking filling: The use of a model eye chamber to study the behaviour of tamponade agents. Ophthalmo-Chirurgie., 16, 147-150.
Basement membranes and artificial substrates in cell transplantation (Journal article)
Sheridan, C., Williams, R., & Grierson, I. (2004). Basement membranes and artificial substrates in cell transplantation. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 242(1), 68-75. doi:10.1007/s00417-003-0800-z
Corrosion (Chapter)
Williams, R. L. (2004). Corrosion. In L. B. Gary, & E. W. Gary (Eds.), the Encyclopedia of Biomaterials and Biomedical Engineering (pp. 399-406). New York: Marcel Dekker, Inc,..
Degradative effects of the biological environment on metals and ceramics (Chapter)
Williams, D. F., & Williams, R. L. (2004). Degradative effects of the biological environment on metals and ceramics. In B. Ratner, A. Hoffman, J. Lemons, & F. Schoen (Eds.), Biomaterials Science: An Introduction to Materials in Medicine (pp. 430-439). San Diego: Academic Press.
Nickel and Nickel Alloys (Chapter)
Williams, R. L. (2004). Nickel and Nickel Alloys. In G. L. Bowlin, & G. E. Wnek (Eds.), Encyclopedia of Biomaterials and Biomedical Engineering (pp. 1066-1074). New York: Marcel Dekker, Inc,.
Tamponade Effect (Chapter)
Williams, R. L., & Wong, D. (2004). Tamponade Effect. In B. Kirchoff, D. Wong, G. K. Krieglstein, & R. N. Weinreb (Eds.), Vitreoretinal Surgery (pp. 147-162). Berlin: Springer.
The effect of silica nanoparticulate coatings on cellular response (Journal article)
Cousins, B. G., Doherty, P. J., Fink, J., Garvey, M. J., & Williams, R. L. (2004). The effect of silica nanoparticulate coatings on cellular response. J. Mater. Sci: Mater. in Med., 15, 353-357.
2003
Biomaterial substrates (PTFE case) (Patent)
Williams, R. L., Garvey, M. J., Fink, J., Williams, R. L., Fink, J., Doherty, P. J., . . . Garvey, M. J. (2003). Biomaterial substrates (PTFE case).
How can combinations of F6H8 and silicone oil be used in the treatment of retinal detachments? (Journal article)
Wetterqvist, C., Wong, D., Williams, R., Stappler, T., Herbert, E., & Freeburn, S. (2003). How can combinations of F6H8 and silicone oil be used in the treatment of retinal detachments?. Ophthalmic Res., 35(S1), 237.
Polymer membranes for RPE transplantation (Journal article)
Williams, R. L., Sheridan, C., & Grierson, I. (2003). Polymer membranes for RPE transplantation. Ophthalmic Res., 35(S1), 3344.
Surface modification of a segmented polyetherurethane using a low-powered gas plasma and its influence on the activation of the coagulation system (Journal article)
Wilson, D. J., Rhodes, N. P., & Williams, R. L. (2003). Surface modification of a segmented polyetherurethane using a low-powered gas plasma and its influence on the activation of the coagulation system. BIOMATERIALS, 24(28), 5069-5081. doi:10.1016/S0142-9612(03)00423-X
2002
Substrates (Silica case) (Patent)
Williams, R. L., Garvey, M. J., Fink, J., Williams, R. L., Fink, J., Doherty, P. J., . . . Garvey, M. J. (2002). Substrates (Silica case).
The effect of thermocycling on five adhesive luting cements (Journal article)
Barclay, C. W., Boyle, E. L., Williams, R., & Marquis, P. M. (2002). The effect of thermocycling on five adhesive luting cements. JOURNAL OF ORAL REHABILITATION, 29(6), 546-552. doi:10.1046/j.1365-2842.2002.00882.x
Effects of plasma treated PET and PTFE on expression of adhesion molecules by human endothelial cells in vitro (Journal article)
Pu, F. R., Williams, R. L., Markkula, T. K., & Hunt, J. A. (2002). Effects of plasma treated PET and PTFE on expression of adhesion molecules by human endothelial cells in vitro. BIOMATERIALS, 23(11), 2411-2428. doi:10.1016/S0142-9612(01)00377-5
Expression of leukocyte-endothelial cell adhesion molecules on monocyte adhesion to human endothelial cells on plasma treated PET and PTFE in vitro (Journal article)
Pu, F. R., Williams, R. L., Markkula, T. K., & Hunt, J. A. (2002). Expression of leukocyte-endothelial cell adhesion molecules on monocyte adhesion to human endothelial cells on plasma treated PET and PTFE in vitro. BIOMATERIALS, 23(24), 4705-4718. doi:10.1016/S0142-9612(02)00219-3
Surface chemical derivatization of plasma-treated PET and PTFE (Journal article)
Markkula, T. K., Hunt, J. A., Pu, F. R., & Williams, R. L. (2002). Surface chemical derivatization of plasma-treated PET and PTFE. SURFACE AND INTERFACE ANALYSIS, 34(1), 583-587. doi:10.1002/sia.1365
2001
An X-ray Photoelectron Spectroscopy study of biomedical polyurethane modified using low-power plasma (Journal article)
Kitching, K. J., Wilson, D. J., Doherty, P. J., & Williams, R. L. (2001). An X-ray Photoelectron Spectroscopy study of biomedical polyurethane modified using low-power plasma. Journal of X-Ray Science and Technology, 9(2), 77-83.
Endoscopic-guided trephination dacryocystorhinostomy (Hesham DCR) - Technique and pilot trial (Journal article)
Ibrahim, H. A., Noble, J. L., Batterbury, M., Johnson, C. P., & Williams, R. (2001). Endoscopic-guided trephination dacryocystorhinostomy (Hesham DCR) - Technique and pilot trial. OPHTHALMOLOGY, 108(12), 2337-2345. doi:10.1016/S0161-6420(01)00813-2
The influence of bracket type on the force delivery of Ni-Ti archwires (Journal article)
Hemingway, R., Williams, R. L., Hunt, J. A., & Rudge, S. J. (2001). The influence of bracket type on the force delivery of Ni-Ti archwires. EUROPEAN JOURNAL OF ORTHODONTICS, 23(3), 233-241. doi:10.1093/ejo/23.3.233
Plasma modification of PTFE surfaces Part II: Plasma-treated surfaces following storage in air or PBS (Journal article)
Wilson, D. J., Williams, R. L., & Pond, R. C. (2001). Plasma modification of PTFE surfaces Part II: Plasma-treated surfaces following storage in air or PBS. SURFACE AND INTERFACE ANALYSIS, 31(5), 397-408. doi:10.1002/sia.1066
Monocyte adhesion and adhesion molecule expression on human endothelial cells on plasma treated PET and PTFE in vitro (Journal article)
Pu, F. R., Williams, R. L., Markkula, T., & Hunt, J. A. (2001). Monocyte adhesion and adhesion molecule expression on human endothelial cells on plasma treated PET and PTFE in vitro. J. Mater. Sci: Mater. in Med. Special Issue,, 12, 970-977.
Monocyte adhesion and adhesion molecule expression on human endothelial cells on plasma-treated PET and PTFE in vitro (Journal article)
Pu, F. R., Williams, R. L., Markkula, T. K., & Hunt, J. A. (2001). Monocyte adhesion and adhesion molecule expression on human endothelial cells on plasma-treated PET and PTFE in vitro. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 12(10-12), 971-977. doi:10.1023/A:1012861116388
Plasma modification of PTFE surfaces Part I: Surfaces immediately following plasma treatment (Journal article)
Wilson, D. J., Williams, R. L., & Pond, R. C. (2001). Plasma modification of PTFE surfaces Part I: Surfaces immediately following plasma treatment. SURFACE AND INTERFACE ANALYSIS, 31(5), 385-396. doi:10.1002/sia.1065
2000
Wettability of chemically modified polymers: Experiment and theory (Journal article)
Wilson, D. J., Pond, R. C., & Williams, R. L. (2000). Wettability of chemically modified polymers: Experiment and theory. INTERFACE SCIENCE, 8(4), 389-399. doi:10.1023/A:1008735929894
Surface chemistry and wettability of plasma-treated PTFE (Journal article)
Wilson, D. J., Eccles, A. J., Steele, T. A., Williams, R. L., & Pond, R. C. (2000). Surface chemistry and wettability of plasma-treated PTFE. SURFACE AND INTERFACE ANALYSIS, 30(1), 36-39. doi:3.0.CO;2-Z">10.1002/1096-9918(200008)30:1<36::AID-SIA801>3.0.CO;2-Z
DOI: 10.1002/1096-9918(200008)30:1<36::AID-SIA801>3.0.CO;2-Z
Biomaterials used in the posterior segment of the eye (Journal article)
Colthurst, M. J., Williams, R. L., Hiscott, P. S., & Grierson, I. (2000). Biomaterials used in the posterior segment of the eye. BIOMATERIALS, 21(7), 649-665. doi:10.1016/S0142-9612(99)00220-3
Gas plasma modification of PET and PTFE (Journal article)
Markkula, T., Hunt, J. A., Pu, F., & Williams, R. L. (2000). Gas plasma modification of PET and PTFE. UKSB First Annual Conference 6-7th July 2000, 35.
1999
The influence of explants on the physical efficiency of tamponade agents (Journal article)
Williams, R., & Wong, D. (1999). The influence of explants on the physical efficiency of tamponade agents. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 237(10), 870-874. doi:10.1007/s004170050325
Conjoint corrosion and wear in titanium alloys (Journal article)
Khan, M. A., Williams, R. L., & Williams, D. F. (1999). Conjoint corrosion and wear in titanium alloys. BIOMATERIALS, 20(8), 765-772. doi:10.1016/S0142-9612(98)00229-4
The corrosion behaviour of Ti-6Al-4V, Ti-6Al-7Nb and Ti-13Nb-13Zr in protein solutions (Journal article)
Khan, M. A., Williams, R. L., & Williams, D. F. (1999). The corrosion behaviour of Ti-6Al-4V, Ti-6Al-7Nb and Ti-13Nb-13Zr in protein solutions. BIOMATERIALS, 20(7), 631-637. doi:10.1016/S0142-9612(98)00217-8
1998
Exchange of perfluorodecalin for gas or oil: a model for avoiding slippage (Journal article)
Wong, D., Williams, R. L., & German, M. J. (1998). Exchange of perfluorodecalin for gas or oil: a model for avoiding slippage. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 236(3), 234-237. doi:10.1007/s004170050070
1997
A study of cell behaviour on the surfaces of multifilament materials (Journal article)
Wan, H., Williams, R. L., Doherty, P. J., & Williams, D. F. (1997). A study of cell behaviour on the surfaces of multifilament materials. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 8(1), 45-51. doi:10.1023/A:1018542313236
1996
The clinical assessment of a ceramic-coated transmucosal dental implant collar (Journal article)
Barclay, C. W., Last, K. S., & Williams, R. (1996). The clinical assessment of a ceramic-coated transmucosal dental implant collar. INTERNATIONAL JOURNAL OF PROSTHODONTICS, 9(5), 466-472. Retrieved from http://gateway.webofknowledge.com/
Titanium alloys - corrosion and wear studies in-vitro (Conference Paper)
Khan, M. A., Williams, R. L., & Williams, D. F. (1996). Titanium alloys - corrosion and wear studies in-vitro. In Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium Vol. 2 (pp. 480).
In-vitro corrosion and wear of titanium alloys in the biological environment (Journal article)
Khan, M. A., Williams, R. L., & Williams, D. F. (1996). In-vitro corrosion and wear of titanium alloys in the biological environment. BIOMATERIALS, 17(22), 2117-2126. doi:10.1016/0142-9612(96)00029-4
1995
Laser surface modification of polymers to improve biocompatibility (Journal article)
Hunt, J. A., Williams, R. L., Tavakoli, S. M., & Riches, S. T. (1995). Laser surface modification of polymers to improve biocompatibility. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 6(12), 813-817. doi:10.1007/BF00134323
Adherence of silicone oil to intraocular lenses. (Journal article)
Wong, D., Williams, R., & Batterbury, M. (1995). Adherence of silicone oil to intraocular lenses.. Eye (London, England), 9 ( Pt 4), 539. doi:10.1038/eye.1995.126
FIBROBLAST ADHESION ONTO METHYL-SILICA GRADIENTS WITH AND WITHOUT PREADSORBED PROTEIN (Journal article)
WILLIAMS, R. L., HUNT, J. A., & TENGVALL, P. (1995). FIBROBLAST ADHESION ONTO METHYL-SILICA GRADIENTS WITH AND WITHOUT PREADSORBED PROTEIN. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 29(12), 1545-1555. doi:10.1002/jbm.820291211
1994
The tensile and shear bond strength of a conventional and a 4-meta self-cure acrylic resin to various surface finishes of CoCr alloy. (Journal article)
Barclay, C. W., & Williams, R. (1994). The tensile and shear bond strength of a conventional and a 4-meta self-cure acrylic resin to various surface finishes of CoCr alloy.. The European journal of prosthodontics and restorative dentistry, 3(1), 5-9.
CONTACT ANGLES OF SUBSTANCES USED FOR INTERNAL TAMPONADE IN RETINAL-DETACHMENT SURGERY (Journal article)
FAWCETT, I. M., WILLIAMS, R. L., & WONG, D. (1994). CONTACT ANGLES OF SUBSTANCES USED FOR INTERNAL TAMPONADE IN RETINAL-DETACHMENT SURGERY. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 232(7), 438-444. doi:10.1007/BF00186587
A PRELIMINARY ASSESSMENT OF POLY(PYRROLE) IN NERVE GUIDE STUDIES (Journal article)
WILLIAMS, R. L., & DOHERTY, P. J. (1994). A PRELIMINARY ASSESSMENT OF POLY(PYRROLE) IN NERVE GUIDE STUDIES. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 5(6-7), 429-433. doi:10.1007/BF00058978
THE CYTOTOXICITY EVALUATION OF KEVLAR AND SILICON-CARBIDE BY MTT ASSAY (Journal article)
WAN, H., WILLIAMS, R. L., DOHERTY, P. J., & WILLIAMS, D. F. (1994). THE CYTOTOXICITY EVALUATION OF KEVLAR AND SILICON-CARBIDE BY MTT ASSAY. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 5(6-7), 441-445. doi:10.1007/BF00058980
A STUDY OF THE REPRODUCIBILITY OF THE MTT TEST (Journal article)
WAN, H., WILLIAMS, R., DOHERTY, P., & WILLIAMS, D. F. (1994). A STUDY OF THE REPRODUCIBILITY OF THE MTT TEST. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 5(3), 154-159. doi:10.1007/BF00053336
BIODEGRADATION OF HYALURONIC-ACID DERIVATIVES BY HYALURONIDASE (Journal article)
ZHONG, S. P., CAMPOCCIA, D., DOHERTY, P. J., WILLIAMS, R. L., BENEDETTI, L., & WILLIAMS, D. F. (1994). BIODEGRADATION OF HYALURONIC-ACID DERIVATIVES BY HYALURONIDASE. BIOMATERIALS, 15(5), 359-365. doi:10.1016/0142-9612(94)90248-8
BIOMECHANICAL ANALYSIS OF A NEW EXTERNAL FIXATION SYSTEM AND ITS CLINICAL-SIGNIFICANCE (Journal article)
WILLIAMS, R. L., AGGARWAL, N. K., & KLENERMAN, L. (1994). BIOMECHANICAL ANALYSIS OF A NEW EXTERNAL FIXATION SYSTEM AND ITS CLINICAL-SIGNIFICANCE. JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 37(1), 66-73. doi:10.1097/00005373-199407000-00013
THE ADHERENCE OF SILICONE OIL TO STANDARD AND HEPARIN-COATED PMMA INTRAOCULAR LENSES (Journal article)
BATTERBURY, M., WONG, D., WILLIAMS, R., & BATES, R. (1994). THE ADHERENCE OF SILICONE OIL TO STANDARD AND HEPARIN-COATED PMMA INTRAOCULAR LENSES. EYE, 8, 547-549. doi:10.1038/eye.1994.135
1993
Non-invasive magnetic resonance imaging of the soft tissue response to a biomaterial. (Journal article)
Khor, E., Hunt, J. A., Martin, P. A., Doherty, P. J., Williams, R. L., & Williams, D. F. (1993). Non-invasive magnetic resonance imaging of the soft tissue response to a biomaterial.. Clinical materials, 12(2), 65-72. doi:10.1016/0267-6605(93)90051-8
1992
Biomaterial-Tissue Interfaces (Book)
Doherty, P. J., Williams, R. L., Williams, D. F., & Lee, A. J. C. (Eds.) (1992). Biomaterial-Tissue Interfaces (Vol. 10). Amsterdam: Elsevier.
PERIBULBAR ANESTHESIA - FAILURE TO ABOLISH THE OCULOCARDIAC REFLEX (Journal article)
BATTERBURY, M., WONG, D., WILLIAMS, R., KELLY, J., & MOSTAFA, S. M. (1992). PERIBULBAR ANESTHESIA - FAILURE TO ABOLISH THE OCULOCARDIAC REFLEX. EYE, 6, 293-295. doi:10.1038/eye.1992.57
1991
XPS STUDIES OF THE BONDING AND HYDROLYSIS OF DENTIN BONDING AGENTS (Journal article)
WILLIAMS, R. L., ALI, S. A. M., & WILLIAMS, D. F. (1991). XPS STUDIES OF THE BONDING AND HYDROLYSIS OF DENTIN BONDING AGENTS. SURFACE AND INTERFACE ANALYSIS, 17(7), 496-498. doi:10.1002/sia.740170714
1989
THE SPATIAL-RESOLUTION OF PROTEIN ADSORPTION ON SURFACES OF HETEROGENEOUS METALLIC BIOMATERIALS (Journal article)
WILLIAMS, R. L., & WILLIAMS, D. F. (1989). THE SPATIAL-RESOLUTION OF PROTEIN ADSORPTION ON SURFACES OF HETEROGENEOUS METALLIC BIOMATERIALS. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 23(3), 339-350. doi:10.1002/jbm.820230305
1988
ALBUMIN ADSORPTION ON METAL-SURFACES (Journal article)
WILLIAMS, R. L., & WILLIAMS, D. F. (1988). ALBUMIN ADSORPTION ON METAL-SURFACES. BIOMATERIALS, 9(3), 206-212. doi:10.1016/0142-9612(88)90085-3
ELECTROCHEMICAL STUDIES ON THE INFLUENCE OF PROTEINS ON THE CORROSION OF IMPLANT ALLOYS (Journal article)
WILLIAMS, R. L., BROWN, S. A., & MERRITT, K. (1988). ELECTROCHEMICAL STUDIES ON THE INFLUENCE OF PROTEINS ON THE CORROSION OF IMPLANT ALLOYS. BIOMATERIALS, 9(2), 181-186. doi:10.1016/0142-9612(88)90119-6
THE EFFECT OF ALBUMIN ON THE WETTABILITY OF PURE METAL AND METAL-OXIDE SURFACES (Journal article)
WILLIAMS, R. L., & WILLIAMS, D. F. (1988). THE EFFECT OF ALBUMIN ON THE WETTABILITY OF PURE METAL AND METAL-OXIDE SURFACES. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 126(2), 596-603. doi:10.1016/0021-9797(88)90159-2
1987
EXPANSION OF A SUCCESSFUL IN-SITU COMBUSTION PILOT IN THE MIDWAY SUNSET FIELD. (Conference Paper)
Williams, R. L., Jones, J. A., & Counihan, T. M. (1987). EXPANSION OF A SUCCESSFUL IN-SITU COMBUSTION PILOT IN THE MIDWAY SUNSET FIELD.. In Society of Petroleum Engineers of AIME, (Paper) SPE Vol. Pi (pp. 7-22). doi:10.2523/16873-ms
PUMP-OFF CONTROL APPLICATION IN THERMAL RECOVERY OPERATIONS. (Conference Paper)
Yoch, R. J., Williams, R. L., & Jones, J. A. (1987). PUMP-OFF CONTROL APPLICATION IN THERMAL RECOVERY OPERATIONS.. In Society of Petroleum Engineers of AIME, (Paper) SPE.
1984
TAFEL SLOPES IN SERUM AND SALINE WHITE STATIC AND FRETTING. (Conference Paper)
Williams, R. L., & Brown, S. A. (1984). TAFEL SLOPES IN SERUM AND SALINE WHITE STATIC AND FRETTING.. In Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium Vol. 7 (pp. 181).