Dr Dan Dan BSc (Hons), MB ChB (Hons), MD, MRCPCH
Senior Lecturer Paediatric Clinical Pharmacology Women's & Children's Health
- +44 (0)151 228 4811 Ext. 2441
- Work email D.Hawcutt@liverpool.ac.uk
Publications
Selected Publications
- Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study (Journal article - 2018)
- 17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use. (Journal article - 2018)
- Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium (Journal article - 2017)
- TPMT, COMT and ACYP2 genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity (Journal article - 2017)
- Childhood asthma exacerbations and the Arg16 beta(2)-receptor polymorphism: A meta-analysis stratified by treatment (Journal article - 2016)
Filter the publication list
2021
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells (Journal article)
de Silva, T. I., Liu, G., Lindsey, B. B., Dong, D., Moore, S. C., Hsu, N. S., . . . Young, P. (2021). The impact of viral mutations on recognition by SARS-CoV-2 specific T cells. iScience, 24(11), 103353. doi:10.1016/j.isci.2021.103353
Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia (Journal article)
Bielicki, J. A., Stöhr, W., Barratt, S., Dunn, D., Naufal, N., Roland, D., . . . Williams, P. (2021). Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia. JAMA, 326(17), 1713. doi:10.1001/jama.2021.17843
Adverse drug reactions of leukotriene receptor antagonists in children with asthma: a systematic review (Journal article)
Dixon, E. G., Rugg-Gunn, C. E. M., Sellick, V., Sinha, I. P., & Hawcutt, D. B. (2021). Adverse drug reactions of leukotriene receptor antagonists in children with asthma: a systematic review. BMJ PAEDIATRICS OPEN, 5(1). doi:10.1136/bmjpo-2021-001206
A prenylated dsRNA sensor protects against severe COVID-19. (Journal article)
Wickenhagen, A., Sugrue, E., Lytras, S., Kuchi, S., Noerenberg, M., Turnbull, M. L., . . . Young, P. (2021). A prenylated dsRNA sensor protects against severe COVID-19.. Science (New York, N.Y.), eabj3624. doi:10.1126/science.abj3624
Assessment of blood pressure and carotid intima media thickness (CIMT) in children with primary adrenal insufficiency (Conference Paper)
Park, J., Shantsila, H., Hawcutt, D., Lip, G., & Blair, J. (2021). Assessment of blood pressure and carotid intima media thickness (CIMT) in children with primary adrenal insufficiency. In HORMONE RESEARCH IN PAEDIATRICS Vol. 94 (pp. 197). Retrieved from http://gateway.webofknowledge.com/
Glucose regulation in children with primary adrenal insufficiency: preliminary data (Conference Paper)
Park, J., Hawcutt, D., Shantsila, H., Lip, G., & Blair, J. (2021). Glucose regulation in children with primary adrenal insufficiency: preliminary data. In HORMONE RESEARCH IN PAEDIATRICS Vol. 94 (pp. 70-71). Retrieved from http://gateway.webofknowledge.com/
Implementing a specialist paediatric clinical pharmacology service in a UK children's hospital (Journal article)
Hawcutt, D. B., Warner, N., Kenyon, E., Murray, C., Taylor, J., Moss, J., . . . Murdock, N. (2021). Implementing a specialist paediatric clinical pharmacology service in a UK children's hospital. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. doi:10.1111/bcp.14944
Identification of ROBO2 as a Potential Locus Associated with Inhaled Corticosteroid Response in Childhood Asthma (Journal article)
Hernandez-Pacheco, N., Gorenjak, M., Li, J., Repnik, K., Vijverberg, S. J., Berce, V., . . . Pino-Yanes, M. (n.d.). Identification of ROBO2 as a Potential Locus Associated with Inhaled Corticosteroid Response in Childhood Asthma. Journal of Personalized Medicine, 11(8), 733. doi:10.3390/jpm11080733
Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study (Journal article)
Drake, T. M., Riad, A. M., Fairfield, C. J., Egan, C., Knight, S. R., Pius, R., . . . Investigator, I. (2021). Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study. LANCET, 398(10296), 223-237. Retrieved from http://gateway.webofknowledge.com/
Soft drinks can be misused to give false “false positive” SARS-CoV-2 lateral flow device results (Journal article)
Oni, L., Hawcutt, D. B., Buchan, I. E., & Semple, M. G. (2021). Soft drinks can be misused to give false “false positive” SARS-CoV-2 lateral flow device results. doi:10.1101/2021.07.05.21260003
COVID-19 and the mental health of children with respiratory illness. (Journal article)
Sinha, I. P., Murphy, R., Biffin, H., Gait, L., Abrams, E. M., Lee, A. R., . . . Brown, A. (2021). COVID-19 and the mental health of children with respiratory illness. LANCET RESPIRATORY MEDICINE, 9(9), 952-954. doi:10.1016/S2213-2600(21)00319-2
Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK (Journal article)
Docherty, A., Mulholland, R., Lone, N. I., Cheyne, C., De Angelis, D., Diaz-Ordaz, K., . . . Investigators, I. (2021). Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK. LANCET RESPIRATORY MEDICINE, 9(7), 773-785. doi:10.1016/S2213-2600(21)00175-2
Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study (Journal article)
Drake, T. M., Fairfield, C. J., Pius, R., Knight, S. R., Norman, L., Girvan, M., . . . ISARIC4C Investigators. (2021). Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study.. The Lancet. Rheumatology, 3(7), e498-e506. doi:10.1016/s2665-9913(21)00104-1
Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19 a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK (Journal article)
Bloom, C. I., Drake, T. M., Docherty, A. B., Lipworth, B. J., Johnston, S. L., Nguyen-Van-Tam, J. S., . . . Investigators, I. S. A. R. I. C. (2021). Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19 a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK. LANCET RESPIRATORY MEDICINE, 9(7), 699-711. doi:10.1016/S2213-2600(21)00013-8
Stepping down asthma treatment in children (Journal article)
King, C., Dixon, E., & Hawcutt, D. B. (2021). Stepping down asthma treatment in children. PEDIATRIC PULMONOLOGY, 56(7), 1823-1824. doi:10.1002/ppul.25410
ADRB2 Haplotypes and Asthma Exacerbations in Children and Young Adults: An Individual Participant Data Meta-Analysis. (Journal article)
Karimi, L., Vijverberg, S. J., Engelkes, M., Hernandez-Pacheco, N., Farzan, N., Soares, P., . . . Consortia, P. S. (2021). ADRB2 haplotypes and asthma exacerbations in children and young adults: An individual participant data meta-analysis. CLINICAL AND EXPERIMENTAL ALLERGY, 51(9), 1157-1171. doi:10.1111/cea.13965
Update and harmonisation of guidance for the management of diabetic ketoacidosis in children and young people in the UK (Journal article)
Rugg-Gunn, C. E. M., Deakin, M., & Hawcutt, D. B. (2021). Update and harmonisation of guidance for the management of diabetic ketoacidosis in children and young people in the UK. BMJ PAEDIATRICS OPEN, 5(1). doi:10.1136/bmjpo-2021-001079
Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study. (Journal article)
Russell, C. D., Fairfield, C. J., Drake, T. M., Turtle, L., Seaton, R. A., Wootton, D. G., . . . ISARIC4C investigators. (2021). Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study.. The Lancet. Microbe, 2(8), e354-e365. doi:10.1016/s2666-5247(21)00090-2
Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial (Journal article)
Horby, P. W., Landray, M. J., & Grp, R. E. C. O. V. E. R. Y. C. (2021). Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial. LANCET, 397(10289), 2049-2059. doi:10.1016/S0140-6736(21)00897-7
Adverse drug reactions in children and young people (Journal article)
Adverse drug reactions in children and young people (2021). Pharmaceutical Journal. doi:10.1211/pj.2021.1.75935
Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use (Journal article)
Hernandez-Pacheco, N., Vijverberg, S. J., Herrera-Luis, E., Li, J., Sio, Y. Y., Granell, R., . . . Consortia, P. I. C. A. S. (2021). Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use. EUROPEAN RESPIRATORY JOURNAL, 57(5). doi:10.1183/13993003.03388-2020
Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial (Journal article)
Horby, P. W., Landray, M. J., & Grp, R. C. (2021). Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. LANCET, 397(10285), 1637-1645. Retrieved from http://gateway.webofknowledge.com/
Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma (Journal article)
Hernandez-Pacheco, N., Gorenjak, M., Jurgec, S., Corrales, A., Jorgensen, A., Karimi, L., . . . Consortia, P. S. (2021). Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma. ALLERGY, 76(4), 1238-1243. doi:10.1111/all.14552
Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study (Journal article)
Gupta, R. K., Harrison, E. M., Ho, A., Docherty, A. B., Knight, S. R., van Smeden, M., . . . Investigators, I. S. A. R. I. C. C. (2021). Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study. LANCET RESPIRATORY MEDICINE, 9(4), 349-359. doi:10.1016/S2213-2600(20)30559-2
Genome-wide association studies of exacerbations in children using long-acting beta2-agonists (Journal article)
Slob, E. M. A., Richards, L. B., Vijverberg, S. J. H., Longo, C., Koppelman, G. H., Pijnenburg, M. W. H., . . . Maitland-van der Zee, A. H. (2021). Genome-wide association studies of exacerbations in children using long-acting beta2-agonists. PEDIATRIC ALLERGY AND IMMUNOLOGY, 32(6), 1197-1207. doi:10.1111/pai.13494
Erratum to “COVID-19 in children: what did we learn from the first wave? [Paediatr Child Health 30 (2020) 438–443/1496] (Journal article)
Bogiatzopoulou, A., Mayberry, H., Hawcutt, D. B., Whittaker, E., Munro, A., Roland, D., . . . Harwood, R. (2021). Erratum to “COVID-19 in children: what did we learn from the first wave? [Paediatr Child Health 30 (2020) 438–443/1496]. Paediatrics and Child Health, 31(3), 128. doi:10.1016/j.paed.2021.01.001
Prospective identification and causality evaluation of suspected adverse drug reactions in neonates (Journal article)
Roberts, E. K., Hawcutt, D. B., & Turner, M. A. (2021). Prospective identification and causality evaluation of suspected adverse drug reactions in neonates. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87(3), 1541-1546. doi:10.1111/bcp.14485
The safety of hydroxychloroquine in paediatric populations: Analysis of worldwide pharmacovigilance reports (Conference Paper)
Hawcutt, D., McWilliam, S., Rodriguez-Martinez, C., Pacheco, R., Hedrich, C., Sinha, I., & Fernandes, R. (2021). The safety of hydroxychloroquine in paediatric populations: Analysis of worldwide pharmacovigilance reports. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 87 (pp. 1622-1623). Retrieved from http://gateway.webofknowledge.com/
Thiopurine methyltransferase activity and adverse effects of azathioprine in at risk paediatric inflammatory bowel disease patients (Conference Paper)
Parry, C., Hawcutt, D., Krishnamurthy, S., & Renji, E. (2021). Thiopurine methyltransferase activity and adverse effects of azathioprine in at risk paediatric inflammatory bowel disease patients. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 87 (pp. 1622). Retrieved from http://gateway.webofknowledge.com/
Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial (Journal article)
Horby, P. W., Roddick, A., Spata, E., Staplin, N., Emberson, J., Pessoa-Amorim, G., . . . Ltd, S. C. C. (2021). Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. LANCET, 397(10274), 605-612. doi:10.1016/S0140-6736(21)00149-5
2020
Pediatric Asthma and COVID-19: the Known, the Unknown and the Controversial. (Journal article)
Abrams, E. M., Sinha, I., Fernandes, R. M., & Hawcutt, D. B. (2020). Pediatric Asthma and COVID-19: the Known, the Unknown and the Controversial.. Pediatric pulmonology. doi:10.1002/ppul.25117
Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease: An International Multicenter Study. (Journal article)
Drake, T. M., Docherty, A. B., Harrison, E. M., Quint, J. K., Adamali, H., Agnew, S., . . . ISARIC4C Investigators. (2020). Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease: An International Multicenter Study.. Am J Respir Crit Care Med. doi:10.1164/rccm.202007-2794OC
Pediatric acute asthma scoring systems: a systematic review and survey of UK practice. (Journal article)
Chacko, J., King, C., Harkness, D., Messahel, S., Grice, J., Roe, J., . . . PERUKI. (2020). Pediatric acute asthma scoring systems: a systematic review and survey of UK practice.. Journal of the American College of Emergency Physicians open, 1(5), 1000-1008. doi:10.1002/emp2.12083
Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation (Conference Paper)
King, C., McKenna, A., Farzan, N., Vijverberg, S. J., van der Schee, M. P., Maitland-van der Zee, A. H., . . . Hawcutt, D. B. (2020). Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation. In PHARMACOGENOMICS JOURNAL Vol. 20 (pp. 621-628). doi:10.1038/s41397-019-0140-y
COVID-19 in children: what did we learn from the first wave? (Journal article)
Bogiatzopoulou, A., Mayberry, H., Hawcutt, D. B., Whittaker, E., Munro, A., Roland, D., . . . Harwood, R. (2020). COVID-19 in children: what did we learn from the first wave?. Paediatrics and child health. doi:10.1016/j.paed.2020.09.005
A systematic review of the impact of food insecurity on the risk of developing asthma, or having poor asthma control, in childhood (Conference Paper)
Mahmood, S., Cheetham, S., Brown, L., Hawcutt, D., Lawrence, P., Mayell, S., . . . Sinha, I. (2020). A systematic review of the impact of food insecurity on the risk of developing asthma, or having poor asthma control, in childhood. In EUROPEAN RESPIRATORY JOURNAL Vol. 56. doi:10.1183/13993003.congress-2020.3510
Salivary cortisol, cortisone and serum cortisol concentrations are related to age and body mass index in healthy children and young people. (Journal article)
Titman, A., Price, V., Hawcutt, D., Chesters, C., Ali, M., Cacace, G., . . . Blair, J. C. (2020). Salivary cortisol, cortisone and serum cortisol concentrations are related to age and body mass index in healthy children and young people.. Clinical endocrinology. doi:10.1111/cen.14294
Child poverty, food insecurity, and respiratory health during the COVID-19 pandemic (Journal article)
Sinha, I. P., Lee, A. R., Bennett, D., McGeehan, L., Abrams, E. M., Mayell, S. J., . . . Taylor-Robinson, D. C. (2020). Child poverty, food insecurity, and respiratory health during the COVID-19 pandemic. The Lancet Respiratory Medicine, 8(8), 762-763. doi:10.1016/s2213-2600(20)30280-0
Correction: Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritization (Journal article)
King, C., McKenna, A., Farzan, N., Vijverberg, S. J., van der Schee, M. P., Maitland-van der Zee, A. H., . . . Hawcutt, D. B. (2020). Correction: Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritization. Pharmacogenomics J. doi:10.1038/s41397-020-0178-x
Pharmacovigilance Reports Received from Children and Young People, and Development of Information to Aid Future Reporting from this Age Group (Journal article)
Bhoombla, N., Preston, J., Ainsworth, J., Bird, H., Jadeja, M., King, C., & Hawcutt, D. B. (2020). Pharmacovigilance Reports Received from Children and Young People, and Development of Information to Aid Future Reporting from this Age Group. PEDIATRIC DRUGS, 22(3), 335-341. doi:10.1007/s40272-020-00391-6
Child poverty, food insecurity, and respiratory health during the COVID-19 pandemic (Journal article)
Sinha, I. P., Lee, A. R., Bennett, D., McGeehan, L., Abrams, E. M., Mayell, S. J., . . . Taylor-Robinson, D. C. (2020). Child poverty, food insecurity, and respiratory health during the COVID-19 pandemic. LANCET RESPIRATORY MEDICINE, 8(8), 762-763. Retrieved from http://gateway.webofknowledge.com/
Efficacy, safety and cost-effectiveness of hydroxychloroquine in children with COVID-19: a call for evidence. (Journal article)
Rodríguez-Martínez, C. E., Fernandes, R. M., Hawcutt, D. B., Sinha, I., & Pacheco, R. L. (2020). Efficacy, safety and cost-effectiveness of hydroxychloroquine in children with COVID-19: a call for evidence.. Acta paediatrica (Oslo, Norway : 1992). doi:10.1111/apa.15373
COVID-19 infection in children (Journal article)
Sinha, I. P., Harwood, R., Semple, M. G., Hawcutt, D. B., Thursfield, R., Narayan, O., . . . Southern, K. W. (2020). COVID-19 infection in children. LANCET RESPIRATORY MEDICINE, 8(5), 446-447. Retrieved from http://gateway.webofknowledge.com/
Fifteen-minute consultation: Pharmacogenomics: a guide for busy clinicians (Journal article)
Parry, C. M., & Hawcutt, D. (2020). Fifteen-minute consultation: Pharmacogenomics: a guide for busy clinicians. ARCHIVES OF DISEASE IN CHILDHOOD-EDUCATION AND PRACTICE EDITION, 105(2), 107-110. doi:10.1136/archdischild-2019-316971
The impact of paediatric dose range checking software (Journal article)
Neame, M., Moss, J., Saez Dominguez, J., Gill, A., Barnes, N., Sinha, I., & Hawcutt, D. (2020). The impact of paediatric dose range checking software. European Journal of Hospital Pharmacy. doi:10.1136/ejhpharm-2020-002244
Patient-focused outcomes are infrequently reported in pediatric health information technology trials: a systematic review (Journal article)
Neame, M. T., Chacko, J., Kirkham, J. J., Sinha, I. P., & Hawcutt, D. B. (2020). Patient-focused outcomes are infrequently reported in pediatric health information technology trials: a systematic review. JOURNAL OF CLINICAL EPIDEMIOLOGY, 119, 117-125. doi:10.1016/j.jclinepi.2019.11.017
Where next for inhaled corticosteroids in childhood asthma? (Journal article)
Sinha, I. P., Dodd, S. R., Grime, C., Hawcutt, D. B., Fernandes, R. M., Roberts, M. R., . . . Williamson, P. R. (2020). Where next for inhaled corticosteroids in childhood asthma?. LANCET RESPIRATORY MEDICINE, 8(4), 345. doi:10.1016/S2213-2600(20)30013-8
2019
Ranitidine in short supply: why now, and where next? (Journal article)
Ryan, M. E., Barker, C., & Hawcutt, D. B. (2020). Ranitidine in short supply: why now, and where next?. ARCHIVES OF DISEASE IN CHILDHOOD, 105(4), 382-383. doi:10.1136/archdischild-2019-318447
Adverse events and cardiovasular effects of vilanterol in paediatric asthma: a systematic review (Conference Paper)
Austin, R., Sinha, I., & Hawcutt, D. (2019). Adverse events and cardiovasular effects of vilanterol in paediatric asthma: a systematic review. In EUROPEAN RESPIRATORY JOURNAL Vol. 54. doi:10.1183/13993003.congress-2019.PA960
Dexamethasone or prednisolone for acute asthma exacerbations in children: a meta-analysis (Conference Paper)
Nitchingham, D., Hawcutt, D., Fernandes, R., Kapitein, B., Andrew, L., Grice, J., . . . Sinha, I. (2019). Dexamethasone or prednisolone for acute asthma exacerbations in children: a meta-analysis. In EUROPEAN RESPIRATORY JOURNAL Vol. 54. doi:10.1183/13993003.congress-2019.PA952
Meta-analysis of inhaled corticosteroids response in children with asthma (Conference Paper)
Hernandez-Pacheco, N., Vijverberg, S. J., Gorenjak, M., Flores, C., Francis, B., Farzan, N., . . . Pino-Yanes, M. (2019). Meta-analysis of inhaled corticosteroids response in children with asthma. In EUROPEAN RESPIRATORY JOURNAL Vol. 54. doi:10.1183/13993003.congress-2019.PA5434
Oral steroids for preschool children with acute wheeze: a systematic review and meta-analysis (Conference Paper)
Murphy, J., King, C., Kapitein, B., Fernandes, R., Lilley, A., Messahel, S., . . . Sinha, I. (2019). Oral steroids for preschool children with acute wheeze: a systematic review and meta-analysis. In EUROPEAN RESPIRATORY JOURNAL Vol. 54. doi:10.1183/13993003.congress-2019.OA4941
The effects of ambient air pollution on the risk of hospitalisation with acute respiratory illnesses in children: an overview of systematic reviews (Conference Paper)
King, C., Surace, A. E., Jeffers, G., Hawcutt, D., & Sinha, I. (2019). The effects of ambient air pollution on the risk of hospitalisation with acute respiratory illnesses in children: an overview of systematic reviews. In EUROPEAN RESPIRATORY JOURNAL Vol. 54. doi:10.1183/13993003.congress-2019.PA2834
Assessing the impact of breathing retraining on asthma symptoms and dysfunctional breathing in children (Journal article)
Hepworth, C., Sinha, I., Saint, G. L., & Hawcutt, D. B. (2019). Assessing the impact of breathing retraining on asthma symptoms and dysfunctional breathing in children. PEDIATRIC PULMONOLOGY, 54(6), 706-712. doi:10.1002/ppul.24300
Genome-wide association study of inhaled corticosteroid response in admixed children with asthma (Journal article)
Hawcutt, D. B., & Pirmohamed, M. (2019). Genome-wide association study of inhaled corticosteroid response in admixed children with asthma. Clinical and Experimental Allergy, 49(6), 789-798. doi:10.1111/cea.13354
A systematic review of the effects of implementing clinical pathways supported by health information technologies (Journal article)
Neame, M. T., Chacko, J., Surace, A. E., Sinha, I. P., & Hawcutt, D. B. (2019). A systematic review of the effects of implementing clinical pathways supported by health information technologies. JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION, 26(4), 356-363. doi:10.1093/jamia/ocy176
Working together to deliver stratified medicine research effectively (Journal article)
Attar, S. G., Poustie, V. J., Hawcutt, D. B., Oni, L., Beresford, M. W., & Pirmohamed, M. (2019). Working together to deliver stratified medicine research effectively. British Medical Bulletin. doi:10.1093/bmb/ldz003
Seizures and quinolone antibiotics in children: a systematic review of adverse events (Journal article)
Neame, M., King, C., Iyer, A. S., Kneen, R., Sinha, I., & Hawcutt, D. B. (2019). Seizures and quinolone antibiotics in children: a systematic review of adverse events. European Journal of Hospital Pharmacy. doi:10.1136/ejhpharm-2018-001805
Contribution of respiratory viruses and bacteria to community-acquired pneumonia in highly vaccinated children: a case-control study. (Journal article)
Saint, G. L., Hawcutt, D. B., & McNamara, P. S. (2019). Contribution of respiratory viruses and bacteria to community-acquired pneumonia in highly vaccinated children: a case-control study.. Thorax. doi:10.1136/thoraxjnl-2018-212625
2018
Quantitation of salbutamol using micro-volume blood sampling - applications to exacerbations of pediatric asthma (Journal article)
Cordell, R. L., Valkenburg, T. S. E., Pandya, H. C., Hawcutt, D. B., Semple, M. G., & Monks, P. S. (2018). Quantitation of salbutamol using micro-volume blood sampling - applications to exacerbations of pediatric asthma. JOURNAL OF ASTHMA, 55(11), 1205-1213. doi:10.1080/02770903.2017.1402341
17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use. (Journal article)
Farzan, N., Vijverberg, S. J., Hernandez-Pacheco, N., Bel, E. H. D., Berce, V., Bonnelykke, K., . . . Maitland-van der Zee, A. -H. (2018). 17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use. ALLERGY, 73(10), 2083-2088. doi:10.1111/all.13499
Identification of a novel locus associated with asthma treatment response with inhaled corticosteroids in African-admixed children (Conference Paper)
Hernandez-Pacheco, N., Farzan, N., Vijverberg, S., Francis, B., Schieck, M., Pirmohamed, M., . . . Consortia, P. S. (2018). Identification of a novel locus associated with asthma treatment response with inhaled corticosteroids in African-admixed children. In EUROPEAN JOURNAL OF HUMAN GENETICS Vol. 26 (pp. 693-694). Retrieved from http://gateway.webofknowledge.com/
The effect of ambient air pollution on the risk of hospitalisation with bronchiolitis in infants: A systematic review. (Conference Paper)
King, C., Hawcutt, D., Kirkham, J., & Sinha, I. (2018). The effect of ambient air pollution on the risk of hospitalisation with bronchiolitis in infants: A systematic review.. In EUROPEAN RESPIRATORY JOURNAL Vol. 52. doi:10.1183/13993003.congress-2018.PA4648
Identifying cisplatin-induced kidney damage in paediatric oncology patients (Journal article)
Barton, C. D., Pizer, B., Jones, C., Oni, L., Pirmohamed, M., & Hawcutt, D. B. (2018). Identifying cisplatin-induced kidney damage in paediatric oncology patients. PEDIATRIC NEPHROLOGY, 33(9), 1467-1474. doi:10.1007/s00467-017-3765-6
The effect of outdoor air pollution on the risk of hospitalisation for bronchiolitis in infants: a systematic review (Journal article)
King, C., Kirkham, J., Hawcutt, D., & Sinha, I. (2018). The effect of outdoor air pollution on the risk of hospitalisation for bronchiolitis in infants: a systematic review. PEERJ, 6. doi:10.7717/peerj.5352
Adrenal suppression with inhaled corticosteroids: the seed and the soil – Authors' reply (Journal article)
Hawcutt, D. B., Francis, B., & Pirmohamed, M. (2018). Adrenal suppression with inhaled corticosteroids: the seed and the soil reply. LANCET RESPIRATORY MEDICINE, 6(6), E20. doi:10.1016/S2213-2600(18)30149-8
Optimising the dosing of intravenous theophylline in acute severe asthma in children (Journal article)
Saint, G. L., Semple, M., Sinha, I., & Hawcutt, D. B. (2018). Optimising the dosing of intravenous theophylline in acute severe asthma in children. Pediatric Drugs, 20(3), 209-214. doi:10.1007/s40272-017-0281-x
Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study (Journal article)
Hawcutt, D. B., Francis, B., Carr, D., Jorgensen, A. L., Yin, P., Wallin, N., . . . Pirmohamed, M. (2018). Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study. The Lancet Respiratory Medicine, 6(6), 442-450. doi:10.1016/S2213-2600(18)30058-4
Solving the problem of dose optimisation of children’s medicines (Journal article)
McWilliam, S., & Hawcutt, D. B. (2018). Solving the problem of dose optimisation of children’s medicines. Expert Review of Clinical Pharmacology, 11(3), 205-208. doi:10.1080/17512433.2018.1431528
2017
O-24 Adrin 1 methodology study: adverse drug reactions in neonates: what are the best ways to evaluate suspected adverse drug reactions in neonates? (Conference Paper)
Roberts., Hawcutt., & Turner. (2017). O-24 Adrin 1 methodology study: adverse drug reactions in neonates: what are the best ways to evaluate suspected adverse drug reactions in neonates?. In Archives of Disease in Childhood Vol. 102 (pp. A11.2-A11). BMJ. doi:10.1136/archdischild-2017-esdppp.24
O-41 Pharmacogenomic studies of corticosteroid effectiveness in paediatric asthma: a systematic review (Conference Paper)
Hawcutt., & Thomas. (2017). O-41 Pharmacogenomic studies of corticosteroid effectiveness in paediatric asthma: a systematic review. In Archives of Disease in Childhood Vol. 102 (pp. A19.1-A19). BMJ. doi:10.1136/archdischild-2017-esdppp.41
Overview of Systematic Reviews of Therapeutic Ranges: Establishing the Threshold of Increased Drug Toxicity (Conference Paper)
Moss, J., Cooney, L., Golder, S., Loke, Y., Jorgensen, A., Sinha, I., & Hawcutt, D. (2017). Overview of Systematic Reviews of Therapeutic Ranges: Establishing the Threshold of Increased Drug Toxicity. In DRUG SAFETY Vol. 40 (pp. 985). Retrieved from http://gateway.webofknowledge.com/
PP-29 Growth hormone dosing in obese children (Conference Paper)
Peak., Hawcutt., Bellis., Price., McCoy., Newland., & Blair. (2017). PP-29 Growth hormone dosing in obese children. In Archives of Disease in Childhood Vol. 102 (pp. A38.2-A39). BMJ. doi:10.1136/archdischild-2017-esdppp.84
PP-34 Adverse drug reactions in neonates: comparing retrospective spontaneous yellow card reports to prospectively collected reports (Conference Paper)
Roberts., Hawcutt., & Turner. (2017). PP-34 Adverse drug reactions in neonates: comparing retrospective spontaneous yellow card reports to prospectively collected reports. In Archives of Disease in Childhood Vol. 102 (pp. A28.1-A28). BMJ. doi:10.1136/archdischild-2017-esdppp.59
PP-43 Pharmacogenomics factors relating to ibuprofen and acute kidney injury in paediatric patients: a systematic review (Conference Paper)
Unsworth., & Hawcutt. (2017). PP-43 Pharmacogenomics factors relating to ibuprofen and acute kidney injury in paediatric patients: a systematic review. In Archives of Disease in Childhood Vol. 102 (pp. A42.1-A42). BMJ. doi:10.1136/archdischild-2017-esdppp.91
Precision dosing to reduce ADRs in children (Conference Paper)
Hawcutt, D. (2017). Precision dosing to reduce ADRs in children. In DRUG SAFETY Vol. 40 (pp. 1040-1041). Retrieved from http://gateway.webofknowledge.com/
Genome-wide association study of asthma exacerbations in European children treated with inhaled corticosteroids (Conference Paper)
Vijverberg, S. J. H., Hernandez-Pacheco, N., Farzan, N., Francis, B., Flores, C., Schieck, M., . . . Maitland-Van der Zee, A. -H. (2017). Genome-wide association study of asthma exacerbations in European children treated with inhaled corticosteroids. In EUROPEAN RESPIRATORY JOURNAL Vol. 50. doi:10.1183/1393003.congress-2017.PA1817
Genome-wide association study of inhaled corticosteroid response in African-admixed children with asthma (Conference Paper)
Hernandez-Pacheco, N., Farzan, N., Vijverberg, S. J., Francis, B., Schieck, M., Pirmohamed, M., . . . Pino-Yanes, M. (2017). Genome-wide association study of inhaled corticosteroid response in African-admixed children with asthma. In EUROPEAN RESPIRATORY JOURNAL Vol. 50. doi:10.1183/1393003.congress-2017.PA4688
Protocol for a prospective observational study of adverse drug reactions of anti-epileptic drugs in children in the UK (Journal article)
Egunsola, O., Sammons, H., Ojha, S., Whitehouse, W., Anderson, M., Hawcutt, D. B., & Choonara, I. (2017). Protocol for a prospective observational study of adverse drug reactions of anti-epileptic drugs in children in the UK. BMJ Paediatrics Open. doi:10.1136/bmjpo-2017-000116
17q21 gene variation increases the risk of exacerbations in asthmatic children treated with inhaled corticosteroids: A meta-analysis in the multi-ethnic pica consortium (Conference Paper)
Farzan, N., Vijverberg, S. J., Hernandez-Pacheco, N., Berce, V., Burchard, E. G., Canino, G., . . . Maitland-Van der Zee, A. H. (2017). 17q21 gene variation increases the risk of exacerbations in asthmatic children treated with inhaled corticosteroids: A meta-analysis in the multi-ethnic pica consortium. In ALLERGY Vol. 72 (pp. 269-270). Retrieved from http://gateway.webofknowledge.com/
Genome-Wide Association Study of Asthma Exacerbations in European Children Treated with Inhaled Corticosteroids (Conference Paper)
Vijverberg, S. J. H., Hernandez-Pacheco, N., Farzan, N., Francis, B., Flores, C., Schieck, M., . . . Maitland-van der Zee, A. -H. (2017). Genome-Wide Association Study of Asthma Exacerbations in European Children Treated with Inhaled Corticosteroids. In PHARMACOEPIDEMIOLOGY AND DRUG SAFETY Vol. 26 (pp. 25-26). Retrieved from http://gateway.webofknowledge.com/
NIHR Clinical Research Networks: what they do and how they help paediatric research (Journal article)
Lythgoe, H., Price, V., Poustie, V., Attar, S., Hawcutt, D., Preston, J., & Beresford, M. W. (2017). NIHR Clinical Research Networks: what they do and how they help paediatric research. ARCHIVES OF DISEASE IN CHILDHOOD, 102(8), 755-759. doi:10.1136/archdischild-2016-311057
Growth hormone prescribing and initial BMI SDS: Increased biochemical adverse effects and costs in obese children without additional gain in height (Journal article)
Hawcutt, D. B., Bellis, J., Price, V., Povall, A., Newland, P., Richardson, P., . . . Blair, J. (2017). Growth hormone prescribing and initial BMI SDS: Increased biochemical adverse effects and costs in obese children without additional gain in height. PLoS One, 12(7). doi:10.1371/journal.pone.0181567
Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium (Journal article)
Hawcutt, D. B., & Pirmohamed, M. (2017). Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium. Pharmacogenomics, 18(10), 931-943. doi:10.2217/pgs-2017-0035
Overview of systematic reviews of therapeutic ranges: methodologies and recommendations for practice. (Journal article)
Cooney, L., Loke, Y. K., Golder, S., Kirkham, J., Jorgensen, A., Sinha, I., & Hawcutt, D. (2017). Overview of systematic reviews of therapeutic ranges: methodologies and recommendations for practice.. BMC medical research methodology, 17(1). doi:10.1186/s12874-017-0363-z
Optimising the use of medicines to reduce acute kidney injury in children and babies (Journal article)
Oni, L., Hawcutt, D. B., Turner, M. A., Beresford, M. W., McWilliam, S., Barton, C., . . . Antoine, D. J. (2017). Optimising the use of medicines to reduce acute kidney injury in children and babies. Pharmacology and Therapeutics, 174, 55-62. doi:10.1016/j.pharmthera.2017.02.018
17q21 Gene Variance Increases The Risk Of Exacerbations In Asthmatic Children Treated With Inhaled Corticosteroids: A Meta-Analysis In The Pica Consortium (Conference Paper)
Farzan, N., Vijverberg, S., Hernandez-Pacheco, N., Berce, V., Burchard, E. G., Canino, G., . . . Maitland-van Der Zee, A. -H. (2017). 17q21 Gene Variance Increases The Risk Of Exacerbations In Asthmatic Children Treated With Inhaled Corticosteroids: A Meta-Analysis In The Pica Consortium. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 195. Washington DC. Retrieved from http://gateway.webofknowledge.com/
Using pharmacokinetic modelling to improve prescribing practices of intravenous aminophylline in childhood asthma exacerbations (Journal article)
Cooney, L., McBride, A., Lilley, A., Sinha, I., Johnson, T. N., & Hawcutt, D. B. (2017). Using pharmacokinetic modelling to improve prescribing practices of intravenous aminophylline in childhood asthma exacerbations. PULMONARY PHARMACOLOGY & THERAPEUTICS, 43, 6-11. doi:10.1016/j.pupt.2017.01.007
TPMT, COMT and ACYP2 genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity (Journal article)
Thiesen, S., Yin, P., Jorgensen, A. L., Zhang, J. E., Manzo, V., McEvoy, L., . . . Pirmohamed, M. (2017). TPMT, COMT and ACYP2 genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity. PHARMACOGENETICS AND GENOMICS, 27(6), 213-222. doi:10.1097/FPC.0000000000000281
2016
Changes in Height and IGF-I SDS in the first year of GH treatment are related to BMI SDS (Conference Paper)
Price, V., Blair, J., & Hawcutt, D. (n.d.). Changes in Height and IGF-I SDS in the first year of GH treatment are related to BMI SDS. In Endocrine Abstracts. Bioscientifica. doi:10.1530/endoabs.45.p69
Home Urine Sampling as a Research Methodology in Longitudinal Biological Research Studies in Children with Cancer - Patient, Parent and Scientific Perspectives (Conference Paper)
Cooper, K., Barton, C., Hemsworth, S., Hincks, E., Hawcutt, D., & Pizer, B. (2016). Home Urine Sampling as a Research Methodology in Longitudinal Biological Research Studies in Children with Cancer - Patient, Parent and Scientific Perspectives. In PEDIATRIC BLOOD & CANCER Vol. 63 (pp. S220-S221). Retrieved from http://gateway.webofknowledge.com/
Nephrotoxicity in Children Receiving Chemotherapy - 'Omics and Biomarkers (Conference Paper)
Barton, C., Pizer, B., Hawcutt, D., Pirmohamed, M., Hemsworth, S., & Hincks, E. (2016). Nephrotoxicity in Children Receiving Chemotherapy - 'Omics and Biomarkers. In PEDIATRIC BLOOD & CANCER Vol. 63 (pp. S121-S122). Retrieved from http://gateway.webofknowledge.com/
Defining uncontrolled childhood asthma in the global PiCA consortium (Conference Paper)
Farzan, N., Vijverberg, S. J., Andiappan, A. K., Blanca-Lopez, N., Bonnelykke, K., Campo, P., . . . Maitland-van der Zee, A. H. (2016). Defining uncontrolled childhood asthma in the global PiCA consortium. In EUROPEAN RESPIRATORY JOURNAL Vol. 48. doi:10.1183/13993003.congress-2016.PA4388
Intravenous theophylline levels in children with acute asthma: A systematic review (Conference Paper)
Cooney, L., Hawcutt, D., & Sinha, I. (2016). Intravenous theophylline levels in children with acute asthma: A systematic review. In EUROPEAN RESPIRATORY JOURNAL Vol. 48. doi:10.1183/13993003.congress-2016.PA314
Aminophylline Dosage In Asthma Exacerbations in Children: A Systematic Review. (Journal article)
Cooney, L., Sinha, I., & Hawcutt, D. (2016). Aminophylline Dosage In Asthma Exacerbations in Children: A Systematic Review. PLOS ONE, 11(8). doi:10.1371/journal.pone.0159965
Defining uncontrolled childhood asthma in the global PiCA consortium (Conference Paper)
Farzan, N., Vijverberg, S. J., Andiappan, A., Palmer, C. J., Tantisira, K. G., Duijts, L., . . . Maitland-van der Zee, A. H. (2016). Defining uncontrolled childhood asthma in the global PiCA consortium. In ALLERGY Vol. 71 (pp. 53). Retrieved from http://gateway.webofknowledge.com/
Childhood asthma exacerbations and the Arg16 beta(2)-receptor polymorphism: A meta-analysis stratified by treatment (Journal article)
Turner, S., Francis, B., Vijverberg, S., Pino-Yanes, M., Maitland-van der Zee, A. H., Basu, K., . . . Asthma, P. C. (2016). Childhood asthma exacerbations and the Arg16 beta(2)-receptor polymorphism: A meta-analysis stratified by treatment. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 138(1), 107-113.E5. doi:10.1016/j.jaci.2015.10.045
Adrenal responses to a low-dose short synacthen test in children with asthma. (Journal article)
Hawcutt, D. B., Jorgensen, A. L., Wallin, N., Thompson, B., Peak, M., Lacy, D., . . . Smyth, R. L. (2016). Adrenal responses to a low-dose short synacthen test in children with asthma (vol 82, pg 648, 2015). CLINICAL ENDOCRINOLOGY, 84(5), 793. doi:10.1111/cen.13069
The Evidence for Intravenous Theophylline Levels between 10-20mg/L in Children Suffering an Acute Exacerbation of Asthma: A Systematic Review (Journal article)
Cooney., sinha., & Hawcutt, D. B. (2016). The Evidence for Intravenous Theophylline Levels between 10-20mg/L in Children Suffering an Acute Exacerbation of Asthma: A Systematic Review. PLoS ONE. doi:10.1371/journal.pone.0153877
G261 Prescribing practices of rituximab in children: a 5-year retrospective review (Conference Paper)
Price, V., Lythgoe, H., Oni, L., & Hawcutt, D. (2016). G261 Prescribing practices of rituximab in children: a 5-year retrospective review. In Archives of Disease in Childhood Vol. 101 (pp. A144-A145). BMJ. doi:10.1136/archdischild-2016-310863.253
G444 Growth hormone: Analysis of actual and ideal body weight prescribing (Conference Paper)
Price, V., Hawcutt, D., Fryer, S., Bellis, J., & Blair, J. (2016). G444 Growth hormone: Analysis of actual and ideal body weight prescribing. In Archives of Disease in Childhood Vol. 101 (pp. A262.2-A262). BMJ. doi:10.1136/archdischild-2016-310863.432
G530(P) Loading doses of IV aminophylline: serum concentrations and clinical outcomes (Conference Paper)
Cooney, L., Hawcutt, D., Sinha, I., Lilley, A., McBride, A., & Lansdale, R. (2016). G530(P) Loading doses of IV aminophylline: serum concentrations and clinical outcomes. In Archives of Disease in Childhood Vol. 101 (pp. A312.3-A313). BMJ. doi:10.1136/archdischild-2016-310863.517
G90(P) Research exposure for UK junior paediatric trainees (Conference Paper)
Lythgoe, H., Price, V., Beresford, M. W., Peak, M., & Hawcutt, D. (2016). G90(P) Research exposure for UK junior paediatric trainees. In Archives of Disease in Childhood Vol. 101 (pp. A52-A53). BMJ. doi:10.1136/archdischild-2016-310863.87
Precision Dosing in Children (Journal article)
Hawcutt, D. B., Cooney, L., Oni, L., & Pirmohamed, M. (2016). Precision Dosing in Children. Expert Review of Precision Medicine and Drug Development, 1(1), 69-78. doi:10.1080/23808993.2016.1138845
Design and conduct of early phase drug studies in children: challenges and opportunities (Journal article)
Rieder, M., & Hawcutt, D. (2016). Design and conduct of early phase drug studies in children: challenges and opportunities. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 82(5), 1308-1314. doi:10.1111/bcp.13058
SPONTANEOUS ADVERSE DRUG REACTION REPORTS FOR NEONATES AND INFANTS IN THE UK 2001–2010 (Journal article)
Hawcutt, D., Maqsood, H., Gomberg, S., Riordan, A., & Turner, M. (2016). SPONTANEOUS ADVERSE DRUG REACTION REPORTS FOR NEONATES AND INFANTS IN THE UK 2001–2010. Archives of Disease in Childhood, 101(1), e1.43-e1. doi:10.1136/archdischild-2015-310148.48
SPONTANEOUS ADVERSE DRUG REACTION REPORTS FOR TRANSPLACENTAL AND TRANSMAMMARY ROUTES IN THOSE =1 YEAR IN THE UK 2001–2010 (Journal article)
Russell, N. -J., Turner, M., & Hawcutt, D. (2016). SPONTANEOUS ADVERSE DRUG REACTION REPORTS FOR TRANSPLACENTAL AND TRANSMAMMARY ROUTES IN THOSE =1 YEAR IN THE UK 2001–2010. Archives of Disease in Childhood, 101(1), e1.21-e1. doi:10.1136/archdischild-2015-310148.28
Spontaneous adverse drug reaction reports for neonates and infants in the UK 2001-2010: content and utility analysis (Journal article)
Hawcutt, D. B., Russell, N. J., Maqsood, H., Kouranloo, K., Gomberg, S., Waitt, C., . . . Turner, M. A. (2016). Spontaneous adverse drug reaction reports for neonates and infants in the UK 2001-2010: content and utility analysis. British journal of clinical pharmacology, 82(06), 1601-1612. doi:10.1111/bcp.13067
2015
Implementation of a clinical protocol for measuring early morning salivary cortisol and cortisone, as a screening test for asthmatics at high risk of adrenal crisis (Conference Paper)
Trinick, R., Doyle, C., McNamara, P., Hawcutt, D., Kelly, E., Worrall, V., & Blair, J. (2015). Implementation of a clinical protocol for measuring early morning salivary cortisol and cortisone, as a screening test for asthmatics at high risk of adrenal crisis. In CLINICAL AND EXPERIMENTAL ALLERGY Vol. 45 (pp. 1908). Retrieved from http://gateway.webofknowledge.com/
UK service level audit of insulin pump therapy in paediatrics (Journal article)
Ghatak, A., Paul, P., Hawcutt, D. B., White, H. D., Furlong, N. J., Saunders, S., . . . Weston, P. J. (2015). UK service level audit of insulin pump therapy in paediatrics. DIABETIC MEDICINE, 32(12), 1652-1657. doi:10.1111/dme.12782
Between patient and inter-time point variability in salivary cortisone: cortisol ratios (Journal article)
Park, J., Lancaster, G., Titman, A., Peak, M., Newlands, P., Collingwood, C., . . . Blair, J. (n.d.). Between patient and inter-time point variability in salivary cortisone: cortisol ratios. Endocrine Abstracts. doi:10.1530/endoabs.39.ep2
ACUTE KIDNEY INJURY IN PAEDIATRIC ONCOLOGY PATIENTS RECEIVING CISPLATIN (Journal article)
Barton, C., Hawcutt, D., Pirmohamed, M., & Pizer, B. (2015). ACUTE KIDNEY INJURY IN PAEDIATRIC ONCOLOGY PATIENTS RECEIVING CISPLATIN. PEDIATRIC BLOOD & CANCER, 62, S302-S303. Retrieved from http://gateway.webofknowledge.com/
MARKERS OF TUBULAR RENAL INJURY IN CHILDREN WITH CANCER RECEIVING CISPLATIN AND/OR IFOSFAMIDE (Journal article)
Barton, C., Hawcutt, D., Pirmohamed, M., & Pizer, B. (2015). MARKERS OF TUBULAR RENAL INJURY IN CHILDREN WITH CANCER RECEIVING CISPLATIN AND/OR IFOSFAMIDE. PEDIATRIC BLOOD & CANCER, 62, S302. Retrieved from http://gateway.webofknowledge.com/
When to report adverse drug reactions in children? (Journal article)
Barton, C., & Hawcutt, D. B. (2015). When to report adverse drug reactions in children?. ARCHIVES OF DISEASE IN CHILDHOOD, 100(7), 682-683. doi:10.1136/archdischild-2014-307906
Pharmacogenetic Markers of Drug Efficacy and Toxicity. (Journal article)
Yip, V., Hawcutt, D., & Pirmohamed, M. (2015). Pharmacogenetic Markers of Drug Efficacy and Toxicity.. Clinical pharmacology and therapeutics, 98(1), 61-70. doi:10.1002/cpt.135
ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults (Journal article)
Vijverberg, S. J. H., Koster, E. S., Tavendale, R., Leusink, M., Koenderman, L., Raaijmakers, J. A. M., . . . Maitland-van der Zee, A. H. (2015). ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults. Clinical and Experimental Allergy, 45(6), 1051-1059. doi:10.1111/cea.12492
Adrenal responses to a low-dose short synacthen test in children with asthma (Journal article)
Hawcutt, D. B., Jorgensen, A. L., Wallin, N., Thompson, B., Peak, M., Lacy, D., . . . Smyth, R. L. (2015). Adrenal responses to a low-dose short synacthen test in children with asthma. CLINICAL ENDOCRINOLOGY, 82(5), 648-656. doi:10.1111/cen.12655
Comparing paediatric intravenous phenytoin doses using physiologically based pharmacokinetic (PBPK) modelling software (Journal article)
Batchelor, H., Appleton, R., & Hawcutt, D. B. (2015). Comparing paediatric intravenous phenytoin doses using physiologically based pharmacokinetic (PBPK) modelling software. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 33, 8-12. doi:10.1016/j.seizure.2015.10.006
2014
Pharmacogenetics of warfarin in a paediatric population: time in therapeutic range, initial and stable dosing and adverse effects. (Journal article)
Hawcutt, D., Ghani, A., Sutton, L., Jorgensen, A., Zhang, E., Murray, M., . . . Pirmohamed, M. (2014). Pharmacogenetics of warfarin in a paediatric population: time in therapeutic range, initial and stable dosing and adverse effects.. The Pharmacogenomics Journal, 14(6), 542-548. doi:10.1038/tpj.2014.31
Adverse drug reactions in neonates: could we be documenting more? (Journal article)
Hawcutt, D. B., O'Connor, O., & Turner, M. A. (2014). Adverse drug reactions in neonates: could we be documenting more?. EXPERT REVIEW OF CLINICAL PHARMACOLOGY, 7(6), 807-820. doi:10.1586/17512433.2014.956090
Assessing the reliability of exome sequencing to detect the filaggrin null mutations R501X and 2282del4 (Conference Paper)
Thompson, B., Hawcutt, D., Carr, D., Bloch, K., Swale, A., Smyth, R., & Pirmohamed, M. (2014). Assessing the reliability of exome sequencing to detect the filaggrin null mutations R501X and 2282del4. In BRITISH JOURNAL OF DERMATOLOGY Vol. 171 (pp. 115-116). Retrieved from http://gateway.webofknowledge.com/
Phenytoin dosing and serum concentrations in paediatric patients requiring 20 mg/kg intravenous loading (Journal article)
Piper, J. D., Hawcutt, D. B., Verghese, G. K., Spinty, S., Newland, P., & Appleton, R. (2014). Phenytoin dosing and serum concentrations in paediatric patients requiring 20 mg/kg intravenous loading. ARCHIVES OF DISEASE IN CHILDHOOD, 99(6), 585-586. doi:10.1136/archdischild-2013-305093
G335(P) Phenytoin dosing and serum concentrations in paediatric patients requiring 20 mg/kg intravenous loading dose (Journal article)
Piper, J., Hawcutt, D., Verghese, G., Spinty, S., Newland, P., & Appleton, R. (2014). G335(P) Phenytoin dosing and serum concentrations in paediatric patients requiring 20 mg/kg intravenous loading dose. Archives of Disease in Childhood, 99(Suppl 1), A138. doi:10.1136/archdischild-2014-306237.318
G365 Medical management of neuropathic pain in complex regional pain syndromes (Journal article)
Hawcutt, D., Whitby, T., & Cleary, G. (2014). G365 Medical management of neuropathic pain in complex regional pain syndromes. Archives of Disease in Childhood, 99(Suppl 1), A150-A151. doi:10.1136/archdischild-2014-306237.348
G409(P) National audit of analgesia post tonsillectomy (Journal article)
O'Connor, O., Hawcutt, D., & Donne, A. (2014). G409(P) National audit of analgesia post tonsillectomy. Archives of Disease in Childhood, 99(Suppl 1), A172. doi:10.1136/archdischild-2014-306237.390
Early morning salivary cortisol and cortisone, and adrenal responses to a simplified low-dose short Synacthen test in children with asthma (Journal article)
Blair, J., Lancaster, G., Titman, A., Peak, M., Newlands, P., Collingwood, C., . . . Couriel, J. (2014). Early morning salivary cortisol and cortisone, and adrenal responses to a simplified low-dose short Synacthen test in children with asthma. CLINICAL ENDOCRINOLOGY, 80(3), 376-383. doi:10.1111/cen.12302
Efficacy and tolerability of zolmitriptan oro-dispersible wafer in treatment of childhood migraine (Journal article)
Kerrison, C., Wright, F., Piper, J., Kumar, R., & Hawcutt, D. B. (2014). Efficacy and tolerability of zolmitriptan oro-dispersible wafer in treatment of childhood migraine. EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE, 21(2), 84-86. doi:10.1136/ejhpharm-2013-000347
Improving the quality of written information available at weekends in a paediatric hospital: the TRANSMIT sheet. (Journal article)
Hawcutt, D., Green, J., Durand, C., Mehta, F., Christopherson, M., & Sinha, I. (2014). Improving the quality of written information available at weekends in a paediatric hospital: the TRANSMIT sheet.. BMJ quality improvement reports, 2(2). doi:10.1136/bmjquality.u202302.w1137
2013
The restrictions to the use of codeine and dilemmas about safe alternatives (Journal article)
Carter, B., Hawcutt, D. B., & Arnott, J. (2013). The restrictions to the use of codeine and dilemmas about safe alternatives. JOURNAL OF CHILD HEALTH CARE, 17(4), 335-337. doi:10.1177/1367493513513663
Paediatric pharmacogenomics: an overview (Journal article)
Hawcutt, D. B., Thompson, B., Smyth, R. L., & Pirmohamed, M. (2013). Paediatric pharmacogenomics: an overview. ARCHIVES OF DISEASE IN CHILDHOOD, 98(3), 232-237. doi:10.1136/archdischild-2012-302852
Paediatric pharmacogenomics: an overview (Journal article)
Hawcutt, D. B., Thompson, B., Smyth, R. L., & Pirmohamed, M. (2013). Paediatric pharmacogenomics: an overview. Archives of Disease in Childhood, 98(3), 232-237. doi:10.1136/archdischild-2012-302852
2012
VARIATION AT GLCCI1: ASSOCIATION WITH INCREASED STEROID DOSE BUT NOT ADRENAL SUPPRESSION IN ASTHMATIC CHILDREN (Journal article)
Thompson, B., Hawcutt, D. B., Carr, D. F., Jorgensen, A. L., Smyth, R. L., & Pirmohamed, M. (2012). VARIATION AT GLCCI1: ASSOCIATION WITH INCREASED STEROID DOSE BUT NOT ADRENAL SUPPRESSION IN ASTHMATIC CHILDREN. THORAX, 67, A17. doi:10.1136/thoraxjnl-2012-202678.037
Decreased milk drinking causing flecainide toxicity in an older child. (Journal article)
Thompson, B., Mangat, J., Barton, C., & Hawcutt, D. B. (2012). Decreased milk drinking causing flecainide toxicity in an older child.. BMJ case reports, 2012. doi:10.1136/bcr.02.2012.5810
Reported paediatric adverse drug reactions in the UK 2000-2009 (Journal article)
Hawcutt, D. B., Mainie, P., Riordan, A., Smyth, R. L., & Pirmohamed, M. (2012). Reported paediatric adverse drug reactions in the UK 2000-2009. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 73(3), 437-446. doi:10.1111/j.1365-2125.2011.04113.x
Acute kidney injury in paediatric cancer patients receiving cisplatin (Journal article)
Barton, C., Oates, A., Hawcutt, D., Pirmohamed, M., & Pizer, B. (2012). Acute kidney injury in paediatric cancer patients receiving cisplatin. Journal of the Royal College of Physicians Edinburgh, 42(Sup, 36â??50.
Reported Paediatric Adverse Drug Reactions in the UK 2000-2009 (Journal article)
Hawcutt, D., Mainie, P., Andrew, R., Smyth, R. L., & Pirmohamed, M. (2012). Reported Paediatric Adverse Drug Reactions in the UK 2000-2009. British Journal of Clinical Pharmacology, 73(3), 437-446.
2011
Serum phenytoin concentrations in paediatric patients following intravenous loading (Journal article)
Hawcutt, D. B., Sampath, S., Timmis, A., Newland, V., Newland, P., & Appleton, R. (2011). Serum phenytoin concentrations in paediatric patients following intravenous loading. ARCHIVES OF DISEASE IN CHILDHOOD, 96(9), 883-884. doi:10.1136/adc.2011.215269
'Lest we forget ...' (Journal article)
Mainie, P., & Hawcutt, D. (2011). 'Lest we forget ...'. ARCHIVES OF DISEASE IN CHILDHOOD, 96(7), 699. doi:10.1136/adc.2010.208363
Twin-twin confusion syndrome: Blood chimerism in opposite sex dizygotic twins (Journal article)
Hawcutt, D., Hammond, B., Sibbring, J., Gokhale, D., Ellis, I., Bricker, L., & Subhedar, N. (2011). Twin-twin confusion syndrome: Blood chimerism in opposite sex dizygotic twins. JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 31(5), 446-448. doi:10.3109/01443615.2011.570813
Adverse drug reactions in children: reports to the UK yellow card scheme 2000-2009 (Journal article)
Hawcutt, D. B., Mainie, P., Appleton, R., Smyth, R., & Pirmohamed, M. (2011). Adverse drug reactions in children: reports to the UK yellow card scheme 2000-2009. Archives of Disease in Childhood, 96(Supplement 1), A57. doi:10.1136/adc.2011.212563.130
"Lest we forget" Letter (Journal article)
Mainie, P., & Hawcutt, D. B. (2011). "Lest we forget" Letter. Archives of Disease in Childhood, 96, 699.
Reported Paediatric Adverse Drug Reactions in the UK 2000-2009 (Journal article)
Hawcutt, D. B., Mainie, P., Appleton, R., Smyth, R. L., & Pirmohamed, M. (2011). Reported Paediatric Adverse Drug Reactions in the UK 2000-2009. Archives of Disease in Childhood, 96, A5.
Reports to the UK Yellow Card Scheme 2000-2009 for medications used in paediatric rheumatology (Journal article)
Hawcutt, D. B., Pain, C., Mulholland, R., Cann, L. M., Cleary, G., Beresford, M. W., & Baildam, E. (2011). Reports to the UK Yellow Card Scheme 2000-2009 for medications used in paediatric rheumatology. Pediatric rheumatology online journal, 9(Suppl 1), P237. doi:10.1186/1546-0096-9-s1-p237
Serum Levels of Phenytoin in Paediatric Patients following an 18mg/kg Intravenous Loading Dose. (Journal article)
Hawcutt, D. B., Sampath, S., Timmis, A., Newland, V., Newland, P., & Appleton, R. (2011). Serum Levels of Phenytoin in Paediatric Patients following an 18mg/kg Intravenous Loading Dose.. Archives of Disease in Childhood, 96(9), 883-884.
Steroid dose, age and gender affect adrenal responses to a low dose short Synacthen test in children with asthma (Journal article)
Hawcutt, D. B., Jorgensen, A. L., Gardner, C., Peak, M., Couriel, J., Lacy, D., . . . Blair, J. (2011). Steroid dose, age and gender affect adrenal responses to a low dose short Synacthen test in children with asthma. Endocrine Abstracts, 27, 32.
Sulthiame in refractory paediatric epilepsies: An experience of an 'old' antiepileptic drug in a tertiary paediatric neurology unit (Journal article)
Swiderska, N., Hawcutt, D., Eaton, V., Stockton, F., Kumar, R., Kneen, R., & Appleton, R. (2011). Sulthiame in refractory paediatric epilepsies: An experience of an 'old' antiepileptic drug in a tertiary paediatric neurology unit. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 20(10), 805-808. doi:10.1016/j.seizure.2011.08.006
2010
MUCOSITIS PREVENTION: EFFICACY OF SUPERSATURATED CALCIUM AND PHOSPHATE SOLUTION IN HIGH RISK PAEDIATRIC ONCOLOGY PATIENTS (Journal article)
Hawcutt, D., Awogbemi, O., Bell, E., & McDowell, H. (2010). MUCOSITIS PREVENTION: EFFICACY OF SUPERSATURATED CALCIUM AND PHOSPHATE SOLUTION IN HIGH RISK PAEDIATRIC ONCOLOGY PATIENTS. PEDIATRIC BLOOD & CANCER, 55(5), 951. Retrieved from http://gateway.webofknowledge.com/
USE OF STEROIDS IN INOTROPE RESISTANT SEPSIS AND AT EXTUBATION IN UK PAEDIATRIC INTENSIVE CARE UNITS - TELEPHONE AUDIT (Journal article)
Hawcutt, D., Sharpe, J., & Parkins, K. (2010). USE OF STEROIDS IN INOTROPE RESISTANT SEPSIS AND AT EXTUBATION IN UK PAEDIATRIC INTENSIVE CARE UNITS - TELEPHONE AUDIT. PEDIATRIC RESEARCH, 68, 626-627. doi:10.1203/00006450-201011001-01265
Points to consider when planning the collection of blood or tissue samples in clinical trials of investigational medicinal products in children, infants and neonates (Chapter)
Hawcutt, D. B., Rose, A. C., Nunn, T., Turner, M. A., & Fuerst-Recktenwald, S. (2010). Points to consider when planning the collection of blood or tissue samples in clinical trials of investigational medicinal products in children, infants and neonates. In Guide to Paediatric Drug Development and Clinical Research (pp. 97-110). doi:10.1159/B978-380559363-2.31557-8
Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon (vol 135, pg 205, 2008) (Journal article)
Lindley, R. M., Hawcutt, D. B., Connell, M. G., & Almond, S. L. (2010). Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon (vol 135, pg 205, 2008). GASTROENTEROLOGY, 138(2), 792.
Mucositis Prevention: Efficacy of Supersaturated Calcium and Phosphate Solution in High Risk Paediatric Oncology Patients (Journal article)
Hawcutt, D. B., Awogbemi, O., Bell, E., & McDowell, H. (2010). Mucositis Prevention: Efficacy of Supersaturated Calcium and Phosphate Solution in High Risk Paediatric Oncology Patients. Paediatric Blood and Cancer, 5(55), 951.
Points to Consider when Planning the Collection of Blood or Tissue Samples in Clinical Trials of Investigational Medicinal Products in Children, Infants and Neonates (Chapter)
Hawcutt, D. B., Rose, A. C., Fuerst-Recktenwald, S., Nunn, T., & Turner, M. A. (2010). Points to Consider when Planning the Collection of Blood or Tissue Samples in Clinical Trials of Investigational Medicinal Products in Children, Infants and Neonates. In Guide to Paediatric Drug Development and Clinical Research (pp. 97-110). KARGER. doi:10.1159/000315578
Points to consider when planning the collection of blood or tissue samples in clinical trials of investigational medicinal products in children, infants and neonates (Chapter)
Hawcutt, D. B., Rose, A. C., Fuerst-Rectenwald, S., Nunn, A. J., & Turner, M. A. (2010). Points to consider when planning the collection of blood or tissue samples in clinical trials of investigational medicinal products in children, infants and neonates. In K. Rose, & J. van den Anker (Eds.), Guide to Paediatric Drug Development and Clinial Research (pp. 96-110). Basel: Karger.
2009
Prioritising neonatal medicines research: UK Medicines for Children Research Network scoping survey (Journal article)
Turner, M. A., Lewis, S., Hawcutt, D. B., & Field, D. (2009). Prioritising neonatal medicines research: UK Medicines for Children Research Network scoping survey. BMC PEDIATRICS, 9. doi:10.1186/1471-2431-9-50
Properties of secondary and tertiary human enteric nervous system neurospheres (Journal article)
Lindley, R. M., Hawcutt, D. B., Connell, M. G., Edgar, D. H., & Kenny, S. E. (2009). Properties of secondary and tertiary human enteric nervous system neurospheres. JOURNAL OF PEDIATRIC SURGERY, 44(6), 1249-1256. doi:10.1016/j.jpedsurg.2009.02.048
Functional analysis of enteric nervous system progenitor cells (Conference Paper)
Edgar, D., Lindley, R., Hawcutt, D., Theocharatos, S., & Kenny, S. (2009). Functional analysis of enteric nervous system progenitor cells. In NEUROGASTROENTEROLOGY AND MOTILITY Vol. 21 (pp. XIII). Retrieved from http://gateway.webofknowledge.com/
Functional analysis of enteric nervous system progenitor cells (Journal article)
Edgar, D. H., Lindley, R. M., Hawcutt, D. B., Theocharatos, S., & Kenny, S. E. (2009). Functional analysis of enteric nervous system progenitor cells. Neurogastroenterology and Motility, 2(21), XIII.
The Effects of Enteric Nervous System Stem Cell Transplantation on the Behaviour of Cultured Samples of Mammalian Distal Colon (Thesis / Dissertation)
Hawcutt, D. B. (2009). The Effects of Enteric Nervous System Stem Cell Transplantation on the Behaviour of Cultured Samples of Mammalian Distal Colon. (PhD Thesis, University of Liverpool).
2008
Drug development for children: How is pharma tackling an unmet need? (Journal article)
Hawcutt, D. B., & Smyth, R. L. (2008). Drug development for children: How is pharma tackling an unmet need?. IDRUGS, 11(11), 502-507.
Drug development for children: How is pharma tackling an unmet need? (Conference Paper)
Hawcutt, D. B., & Smyth, R. L. (2008). Drug development for children: How is pharma tackling an unmet need?. In IDRUGS Vol. 11 (pp. 502-507). Retrieved from http://gateway.webofknowledge.com/
Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon. (Journal article)
Lindley, R., Hawcutt, D., Connell, G., Almond, S., Vannucchi, M. -G., Faussone-Pellegrini, M. S., . . . Kenny, S. (2008). Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon.. Gastroenterology, 135(1), 205-216.
The new European regulation on pediatric medicines: regulatory perspective. (Journal article)
Hawcutt, D. B., & Smyth, R. L. (2008). The new European regulation on pediatric medicines: regulatory perspective.. Paediatric drugs, 10(3), 143-146. doi:10.2165/00148581-200810030-00002
One size does not fit all: getting drug doses right for children (Journal article)
Hawcutt, D. B., & Smyth, R. L. (2008). One size does not fit all: getting drug doses right for children. ARCHIVES OF DISEASE IN CHILDHOOD, 93(3), 190-191. doi:10.1136/adc.2007.127951
Chapter 9: Advances towards the Development of a Stem Cell Therapy for Hirschsprung's Disease (Chapter)
Hawcutt, D. B., Lindley, R. M., Kenny, S. E., & Edgar, D. H. (2008). Chapter 9: Advances towards the Development of a Stem Cell Therapy for Hirschsprung's Disease. In Stem Cell Research Progress (pp. 137-157). New York: Nova Science Publishers.
Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon (Journal article)
Lindley, R. M., Hawcutt, D. B., Connell, M. G., Almond, S. N., Vannucchi, M. -G., Faussone-Pellegrini, M. S., . . . Kenny, S. E. (2008). Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon. GASTROENTEROLOGY, 135(1), 205-216. doi:10.1053/j.gastro.2008.03.035
Paediatric Pharmacogenomics - Challenges and Opportunities. 2008; 2(1): 13-15 (Journal article)
Hawcutt, D. B., & Pirmohamed, M. (2008). Paediatric Pharmacogenomics - Challenges and Opportunities. 2008; 2(1): 13-15. European Paediatrics, 2(1), 13-15.
Points to consider when planning the collection of blood samples in clinical trials of investigational medicinal products. (Report)
Hawcutt, D. B., Rose, A. C., Nunn, T., & Turner, M. A. (2008). Points to consider when planning the collection of blood samples in clinical trials of investigational medicinal products.. Liverpool: Medicines for Children Research Network. Retrieved from http://ctuprod.liv.ac.uk/mcrnweb/images/mcrn_guide_for_blood_sampling_v1.0.pdf
The New European Regulation on Paediatric Medicines: Regulatory Perspective (Journal article)
Hawcutt, D. B., & Smyth, R. L. (2008). The New European Regulation on Paediatric Medicines: Regulatory Perspective. Pediatric Drugs, 10(3), 143-146.
2007
Advances towards the development of a stem cell therapy for Hirschsprung's disease (Journal article)
Hawcutt, D. B., Lindley, R. M., Kenny, S. E., & Edgar, D. H. (2007). Advances towards the development of a stem cell therapy for Hirschsprung's disease. Journal of Stem Cells, 2(2), 105-119.
Restoration of function following mouse and human enteric nervous system transplants into an in vitro model of Hirschsprung's disease (Journal article)
Hawcutt, D., Lindley, R., Edgar, D., & Kenny, S. (2007). Restoration of function following mouse and human enteric nervous system transplants into an in vitro model of Hirschsprung's disease. GASTROENTEROLOGY, 132(4), A577. Retrieved from http://gateway.webofknowledge.com/
Advances towards a stem cell therapy for Hirschprung's disease (Journal article)
Hawcutt, D. L. R. K. S., & Edgar, D. H. (2007). Advances towards a stem cell therapy for Hirschprung's disease. Journal of Stem Cells, 2, 41-47.
Functional rescue following mouse enteric nervous system transplant into an in vitro model of Hirschsprung's disease occurs via Nitric Oxide signalling (Journal article)
Hawcutt, D. B., Lindley, R. M., Edgar, D. H., & Kenny, S. E. (2007). Functional rescue following mouse enteric nervous system transplant into an in vitro model of Hirschsprung's disease occurs via Nitric Oxide signalling. Journal of Perinatology, 27, 626.
Restoration of normal function following mouse enteric nervous system transplant into an in vitro model of Hirschsprung's disease (Journal article)
Hawcutt, D. B., Lindley, R. M., Edgar, D. H., & Kenny, S. E. (2007). Restoration of normal function following mouse enteric nervous system transplant into an in vitro model of Hirschsprung's disease. Archives of Disease in Childhood, 92(Suppl), A4-A5.