Prof Alan Nahum

Physics

Publications

2018

Investigation of the effect of natural tumor cell death on radiotherapy outcomes (Journal article)

Stavrev, P., Stavreva, N., Penev, D., Nahum, A., Ruggieri, R., & Pressyanov, D. (2018). Investigation of the effect of natural tumor cell death on radiotherapy outcomes. PHYSICS IN MEDICINE AND BIOLOGY, 63(20). doi:10.1088/1361-6560/aae05d

DOI: 10.1088/1361-6560/aae05d

Origins of the changing detector response in small megavoltage photon radiation fields (Journal article)

Fenwick, J. D., Georgiou, G., Rowbottom, C. G., Underwood, T. S. A., Kumar, S., & Nahum, A. E. (2018). Origins of the changing detector response in small megavoltage photon radiation fields. PHYSICS IN MEDICINE AND BIOLOGY, 63(12). doi:10.1088/1361-6560/aac478

DOI: 10.1088/1361-6560/aac478

TCP and Gaussian Radiosensitivities (Conference Paper)

Stavrev, P., Stavreva, N., Nahum, A., & Pressyanov, D. (2018). TCP and Gaussian Radiosensitivities. In RADIOTHERAPY AND ONCOLOGY Vol. 127 (pp. S1080-S1081). doi:10.1016/S0167-8140(18)32296-5

DOI: 10.1016/S0167-8140(18)32296-5

2017

Fixed 3.7-GBq 131I Activity for Metastatic Thyroid Cancer Therapy Ignores Science and History. (Journal article)

Jentzen, W., Nahum, A. E., Bockisch, A., Binse, I., & Tulchinsky, M. (2017). Fixed 3.7-GBq 131I Activity for Metastatic Thyroid Cancer Therapy Ignores Science and History.. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 58(9), 1530. doi:10.2967/jnumed.117.192872

DOI: 10.2967/jnumed.117.192872

Increasing the power of tumour control and normal tissue complication probability modelling in radiotherapy: recent trends and current issues (Journal article)

Tommasino, F., Nahum, A., & Cella, L. (2017). Increasing the power of tumour control and normal tissue complication probability modelling in radiotherapy: recent trends and current issues. TRANSLATIONAL CANCER RESEARCH, 6, S807-S821. doi:10.21037/tcr.2017.06.03

DOI: 10.21037/tcr.2017.06.03

Average energy required to produce an ion pair, revisited (Journal article)

Fourkal, E., Nahum, A., MA, C., & Paskalev, K. (n.d.). Average energy required to produce an ion pair, revisited. Retrieved from http://arxiv.org/abs/1703.10032v1

2016

Fast and high temperature hyperthermia coupled with radiotherapy as a possible new treatment for glioblastoma. (Journal article)

Borasi, G., Nahum, A., Paulides, M. M., Powathil, G., Russo, G., Fariselli, L., . . . Gilardi, M. C. (2016). Fast and high temperature hyperthermia coupled with radiotherapy as a possible new treatment for glioblastoma.. Journal of therapeutic ultrasound, 4, 32. doi:10.1186/s40349-016-0078-3

DOI: 10.1186/s40349-016-0078-3

Twenty Fraction Prostate Radiotherapy with Intra-prostatic Boost: Results of a Pilot Study (Journal article)

Onjukka, E., Uzan, J., Baker, C., Howard, L., Nahum, A., & Syndikus, I. (2017). Twenty Fraction Prostate Radiotherapy with Intra-prostatic Boost: Results of a Pilot Study. CLINICAL ONCOLOGY, 29(1), 6-14. doi:10.1016/j.clon.2016.09.009

DOI: 10.1016/j.clon.2016.09.009

Optimal dose and fraction number in SBRT of lung tumours: A radiobiological analysis. (Journal article)

Ruggieri, R., Stavrev, P., Naccarato, S., Stavreva, N., Alongi, F., & Nahum, A. E. (2017). Optimal dose and fraction number in SBRT of lung tumours: A radiobiological analysis.. Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), 44, 188-195. doi:10.1016/j.ejmp.2016.12.012

DOI: 10.1016/j.ejmp.2016.12.012

Modelling the radiotherapy effect in the reaction-diffusion equation (Journal article)

Borasi, G., & Nahum, A. (2016). Modelling the radiotherapy effect in the reaction-diffusion equation. PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 32(9), 1175-1179. doi:10.1016/j.ejmp.2016.08.020

DOI: 10.1016/j.ejmp.2016.08.020

Impact of microscopic disease extension, extra-CTV tumour islets, incidental dose and dose conformity on tumour control probability (Journal article)

Selvaraj, J., Baker, C., & Nahum, A. (2016). Impact of microscopic disease extension, extra-CTV tumour islets, incidental dose and dose conformity on tumour control probability. AUSTRALASIAN PHYSICAL & ENGINEERING SCIENCES IN MEDICINE, 39(2), 493-500. doi:10.1007/s13246-016-0446-x

DOI: 10.1007/s13246-016-0446-x

Dosimetric response of variable-size cavities in photon-irradiated media and the behaviour of the Spencer-Attix cavity integral with increasing Delta (Journal article)

Kumar, S., Deshpande, D. D., & Nahum, A. E. (2016). Dosimetric response of variable-size cavities in photon-irradiated media and the behaviour of the Spencer-Attix cavity integral with increasing Delta. PHYSICS IN MEDICINE AND BIOLOGY, 61(7), 2680-2704. doi:10.1088/0031-9155/61/7/2680

DOI: 10.1088/0031-9155/61/7/2680

Prostate Dose-painting Radiotherapy and Radiobiological Guided Optimisation Enhances the Therapeutic Ratio (Journal article)

Uzan, J., Nahum, A. E., & Syndikus, I. (2016). Prostate Dose-painting Radiotherapy and Radiobiological Guided Optimisation Enhances the Therapeutic Ratio. CLINICAL ONCOLOGY, 28(3), 165-170. doi:10.1016/j.clon.2015.09.006

DOI: 10.1016/j.clon.2015.09.006

Secondary bremsstrahlung and the energy-conservation aspects of kerma in photon-irradiated media (Journal article)

Kumar, S., & Nahum, A. E. (2016). Secondary bremsstrahlung and the energy-conservation aspects of kerma in photon-irradiated media. PHYSICS IN MEDICINE AND BIOLOGY, 61(3), 1389-1402. doi:10.1088/0031-9155/61/3/1389

DOI: 10.1088/0031-9155/61/3/1389

2015

Breakdown of Bragg-Gray behaviour for low-density detectors under electronic disequilibrium conditions in small megavoltage photon fields (Journal article)

Kumar, S., Fenwick, J. D., Underwood, T. S. A., Deshpande, D. D., Scott, A. J. D., & Nahum, A. E. (2015). Breakdown of Bragg-Gray behaviour for low-density detectors under electronic disequilibrium conditions in small megavoltage photon fields. PHYSICS IN MEDICINE AND BIOLOGY, 60(20), 8187-8212. doi:10.1088/0031-9155/60/20/8187

DOI: 10.1088/0031-9155/60/20/8187

On differences in radiosensitivity estimation: TCP experiments versus survival curves. A theoretical study (Journal article)

Stavrev, P., Stavreva, N., Ruggieri, R., & Nahum, A. (2015). On differences in radiosensitivity estimation: TCP experiments versus survival curves. A theoretical study. PHYSICS IN MEDICINE AND BIOLOGY, 60(15), N293-N299. doi:10.1088/0031-9155/60/15/N293

DOI: 10.1088/0031-9155/60/15/N293

The performance of normal-tissue complication probability models in the presence of confounding factors (Journal article)

Onjukka, E., Baker, C., & Nahum, A. (2015). The performance of normal-tissue complication probability models in the presence of confounding factors. MEDICAL PHYSICS, 42(5), 2326-2341. doi:10.1118/1.4917219

DOI: 10.1118/1.4917219

Monte-Carlo-derived insights into dose-kerma-collision kerma inter-relationships for 50 keV-25 MeV photon beams in water, aluminium and copper (vol 60, pg 501, 2015) (Journal article)

Kumar, S., Deshpande, D. D., & Nahum, A. E. (2015). Monte-Carlo-derived insights into dose-kerma-collision kerma inter-relationships for 50 keV-25 MeV photon beams in water, aluminium and copper (vol 60, pg 501, 2015). PHYSICS IN MEDICINE AND BIOLOGY, 60(6), 2621-2624. doi:10.1088/0031-9155/60/6/2621

DOI: 10.1088/0031-9155/60/6/2621

Monte-Carlo-derived insights into dose-kerma-collision kerma inter-relationships for 50 keV-25 MeV photon beams in water, aluminum and copper (Journal article)

Kumar, S., Deshpande, D. D., & Nahum, A. E. (2015). Monte-Carlo-derived insights into dose-kerma-collision kerma inter-relationships for 50 keV-25 MeV photon beams in water, aluminum and copper. PHYSICS IN MEDICINE AND BIOLOGY, 60(2), 501-519. doi:10.1088/0031-9155/60/2/501

DOI: 10.1088/0031-9155/60/2/501

4D radiobiological modelling of the interplay effect in conventionally and hypofractionated lung tumour IMRT (Journal article)

Selvaraj, J., Uzan, J., Baker, C., & Nahum, A. (2015). 4D radiobiological modelling of the interplay effect in conventionally and hypofractionated lung tumour IMRT. BRITISH JOURNAL OF RADIOLOGY, 88(1045). doi:10.1259/bjr.20140372

DOI: 10.1259/bjr.20140372

Comment on "Simulating Radiotherapy Effect in High-Grade Glioma by Using Diffusive Modeling and Brain Atlases". (Journal article)

Borasi, G., & Nahum, A. E. (2015). Comment on "Simulating Radiotherapy Effect in High-Grade Glioma by Using Diffusive Modeling and Brain Atlases".. BioMed Research International, 2015, 801057. doi:10.1155/2015/801057

DOI: 10.1155/2015/801057

The radiobiology of hypofractionation. (Journal article)

Nahum, A. E. (2015). The radiobiology of hypofractionation.. Clinical oncology (Royal College of Radiologists (Great Britain)), 27(5), 260-269. doi:10.1016/j.clon.2015.02.001

DOI: 10.1016/j.clon.2015.02.001

2014

Letter regarding Meade et al. entitled "Models of acute mucosal tolerance to radiotherapy alone applied to synchronous chemo-radiation schedules in head and neck cancer" (Journal article)

Fenwick, J. D., Malik, Z., Nahum, A. E., & Mayles, W. P. M. (2014). Letter regarding Meade et al. entitled "Models of acute mucosal tolerance to radiotherapy alone applied to synchronous chemo-radiation schedules in head and neck cancer". TUMOR BIOLOGY, 35(12), 12777-12778. doi:10.1007/s13277-014-2874-0

DOI: 10.1007/s13277-014-2874-0

Experimental evidence for the use of ultrasound to increase tumor-cell radiosensitivity (Journal article)

Borasi, G., Russo, G., Vicari, F., Nahum, A., & Gilardi, M. C. (2014). Experimental evidence for the use of ultrasound to increase tumor-cell radiosensitivity. TRANSLATIONAL CANCER RESEARCH, 3(5), 512-520. doi:10.3978/j.issn.2218-676X.2014.10.05

DOI: 10.3978/j.issn.2218-676X.2014.10.05

Cancer Therapy Combining High-Intensity Focused Ultrasound and Megavoltage Radiation (Journal article)

Borasi, G., Melzer, A., Russo, G., Nahum, A., Zhang, Q., Alongi, F., . . . Gilardi, M. C. (2014). Cancer Therapy Combining High-Intensity Focused Ultrasound and Megavoltage Radiation. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 89(4), 926-927. doi:10.1016/j.ijrobp.2014.03.025

DOI: 10.1016/j.ijrobp.2014.03.025

4D Radiobiology (Journal article)

Fourkal, E., Hossain, M., Veltchev, I., Ma, C., Meyer, J., Horwitz, E., & Nahum, A. (2014). 4D Radiobiology. MEDICAL PHYSICS, 41(6), 313. doi:10.1118/1.4888718

DOI: 10.1118/1.4888718

Optimizing Collimator Margins for Isotoxically Dose-Escalated Conformal Radiation Therapy of Non-Small Cell Lung Cancer (Journal article)

Warren, S., Panettieri, V., Panakis, N., Bates, N., Lester, J. F., Jain, P., . . . Fenwick, J. D. (2014). Optimizing Collimator Margins for Isotoxically Dose-Escalated Conformal Radiation Therapy of Non-Small Cell Lung Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 88(5), 1148-1153. doi:10.1016/j.ijrobp.2013.12.034

DOI: 10.1016/j.ijrobp.2013.12.034

Dose escalation in the I-START trial - ISoToxic Accelerated RadioTherapy in locally advanced non-small cell lung cancer (Journal article)

Nixon, L. S., Lester, J. F., Mayles, P., Mayles, H., Parsons, E., Ionescu, A., . . . Griffiths, G. (2014). Dose escalation in the I-START trial - ISoToxic Accelerated RadioTherapy in locally advanced non-small cell lung cancer. LUNG CANCER, 83, S54. doi:10.1016/S0169-5002(14)70149-7

DOI: 10.1016/S0169-5002(14)70149-7