Photo of Dr Graeme Sills

Dr Graeme Sills BSc (Hons), PhD

Senior Lecturer Translational Medicine

Research

Research interests

My principal research interests lie in the mechanisms and predictors of drug responsiveness in epilepsy, with specific focus on antiepileptic drug pharmacology, molecular and cellular mechanisms of drug resistance in epilepsy and epilepsy pharmacogenetics.

Research Grants

MICA: Towards using historical data for research prioritisation in children

MEDICAL RESEARCH COUNCIL (MRC)

March 2015 - February 2018

Profiling oxidative stress in differentiated neuroblastoma cells

WELLCOME TRUST (UK)

June 2015 - August 2015

A pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)

DEPARTMENT OF HEALTH (UK) (NIHR)

June 2012 - November 2019

Exploring oxidative stress pathways in epilepsy

REPUBLIC OF IRAQ MINISTRY OF EDUCATION

October 2014 - September 2017

Antiepileptic drug transport at the blood-brain barrier; more than just P-glycoprotein

EPILEPSY RESEARCH UK (UK)

October 2010 - September 2014

Genetic markers for carbamazepine-induced hypersensitivty syndrome

EPILEPSY RESEARCH UK (UK)

June 2012 - November 2013

Refractory Juvenile Myoclonoc Epilepsy Cohort (ReJuMEC)

MEDICAL RESEARCH COUNCIL (MRC)

January 2009 - June 2011

Epilepsy Pharmacogenomics: delivering biomarkers for clinical use (EpiPGX)

EUROPEAN COMMISSION

October 2011 - September 2016

WELLCOME VIP 2007/08

WELLCOME TRUST (UK)

October 2008 - September 2009

Identification of causal genetic variants in patients with neuromyelitis optica

WELLCOME TRUST (UK)

July 2013 - August 2013

Proteomic profiling of epileptic brain

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL (BBSRC)

July 2011 - October 2013

Research Collaborations

Alan Morgan

Internal

Prof Sanjay Sisodiya

External: University College London

Dr Mike Johnson

External: Imperial College London

Tony Marson

Internal

John Quinn

Internal

Munir Pirmohamed

Internal

Prof Mark Rees

External: University of Swansea

Prof Terence O'Brien

External: University of Melbourne

Dr Bethan Lang

External: University of Oxford

Dr Elizabeth de Lange

External: University of Leiden

Prof Martin Brodie

External: University of Glasgow