2013 Papers

  • Suthers JM, Pinchbeck GL, Proudman CJ, Archer DC. Survival of horses following strangulating large colon volvulus. Equine Vet J. 2013 Mar;45(2):219-23.
  • Musumba CO, Jorgensen A, Sutton L, Van Eker D, Zhang E, O'Hara N, Carr DF, Pritchard DM, Pirmohamed M. CYP2C19*17 gain-of-function polymorphism is associated with peptic ulcer disease. Clin Pharmacol Ther. 2013 Feb;93(2):195-203. doi: 10.1038/clpt.2012.215. Epub 2012 Oct 26
  • Vinjamuri S, Gilbert TM, Banks M, McKane G, Maltby P, Poston G, Weissman H, Palmer DH, Vora J, Pritchard DM, Cuthbertson DJ. Peptide receptor radionuclide therapy with (90)Y-DOTATATE/(90)Y-DOTATOC in patients with progressive metastatic neuroendocrine tumours: assessment of response, survival and toxicity. Br J Cancer. 2013 Apr 16;108(7):1440-8. doi: 10.1038/bjc.2013.103. Epub 2013 Mar 14
  • Ahmed I, Greenwood R, Costello Bde L, Ratcliffe NM, Probert CS. An investigation of fecal volatile organic metabolites in irritable bowel syndrome. PLoS One. 2013;8(3):e58204. doi: 10.1371/journal.pone.0058204. Epub 2013 Mar 13.
  • Khalid, TY; Saad, S; Greenman, J; De Lacy Costello, B; Probert, CSJ; Ratcliffe, NM. (2013) Volatiles from oral anaerobes confounding breath biomarker discovery. Journal of Breath Research, 7(1). Link.
  • Murugesan SV, Steele IA, Dimaline R, Poston GJ, Shrotri M, Campbell F, Varro A, Pritchard DM. Correlation between a short-term intravenous octreotide suppression test and response to antrectomy in patients with type-1 gastric neuroendocrine tumours. Eur J Gastroenterol Hepatol. 2013 Apr;25(4):474-81. doi: 10.1097/MEG.0b013e32835cec52.
  • Duckworth,C.A.; Clyde,D.; Worthley,D.L.; Wang,T.C.; Varro,A.; Pritchard,D.M. (2013) Progastrin-Induced Secretion of Insulin-Like Growth Factor-2 from Colonic Myofibroblasts Stimulates Colonic Epithelial Proliferation in Mice. Gastroenterology. 2013 Mar 19. doi:pii: S0016-5085(13)00356-9. 10.1053/j.gastro.2013.03.012. [Epub ahead of print]
  • Shawihdi M, Thompson E, Kapoor N, Powell G, Sturgess R, Stern N, Roughton M, Pearson MG, Bodger K. Variation in gastroscopy rate in English general practice and outcome for oesophagogastric cancer: retrospective analysis of Hospital Episode Statistics. Gut 2013;(In Press).

    In this study of over 20,000 cases of oesophagogastric cancer in England we show that inequality in cancer outcome is associated with variation in general practice referral rates for gastroscopy. It has immediate and important policy implications and we anticipate it will create a good deal of interest and inform the current NICE review of dyspepsia guidelines. So, a paper of genuine 'translational' importance in terms of influencing clinical practice.
  • Roberts CL, Keita ÅV, Parsons BN, Prorok-Hamon M, Knight P, Friswell MK, Winstanley C, O’Kennedy N, Söderholm JD, Rhodes JM, Campbell BJ (2012). Soluble plantain fibre blocks epithelial adhesion and M-cell translocation of intestinal pathogens. Journal of Nutritional Biochemistry 24(1): 97–103.
  • Roberts CL, Rushworth SL, Richman E and Rhodes JM. Increased consumption of emulsifiers as an explanation for the rising incidence of Crohn's disease. Journal of Crohn’s and Colitis (2013) J Crohns Colitis. 2013 May 1;7(4):338-41. doi: 10.1016/j.crohns.2013.01.004. Epub 2013 Jan 27. Link.
  • Chen C, Duckworth CA, Zhao Q, Pritchard DM, Rhodes JM, Yu LG. (2013). Increased circulation of galectin-3 in cancer induces secretion of metastasis-promoting cytokines from blood vascular endothelium. Clin Cancer Res. 2013 Apr 1;19(7):1693-704
  • Probert C. Steroids and 5-aminosalicylic acids in moderate ulcerative colitis: addressing the dilemma. Therap Adv Gastroenterol. 2013 Jan;6(1):33-8.
  • Barrow H, Rhodes JM and Yu LG. (2013). Simultaneous determination of serum galectin-3 and -4 levels detects metastasis in colorectal cancer patients. Cell Oncol 36:9-13.
  • Dong X, Yu LG, Sun R, Cheng YN, Cao H, Yang KM, Dong YN, Wu Y, Guo XL. (2013). Inhibition of PTEN expression and activity by angiotensin II induces proliferation and migration of vascular smooth muscle cells. J Cell Biochem. 114:174-82.
  • Duckworth CA, Yu LG (2013). Galectins in the blood circulation: potential therapeutic targets of cancer metastasis. In: Galectins and Diseases: Implications for Targeted Therapeutics. (eds by A Klyosov)  ACS Publications, Washington DC. p310-322.
  • Barrow H, TamB, Duckworth CA, Rhodes JM and Yu LG. Suppression of C1GalT is associated with reduction of TF and reciprocal increase of Tn, sialyl-Tn and Core 3 glycans in human colon cancer cells. PLoS One8:e59792. Link.
  • Susan Kenny ; Islay Steele; Suzanne Lyons; Andrew R. Moore; Senthil V. Murugesan; Laszlo Tiszlavicz; Rod Dimaline; D. Mark Pritchard; Andrea Varro; Graham J. Dockray (2013). The role of plasminogen activator inhibitor (PAI)-1 in gastric mucosal protection. AJP GI&Liver, Ahead of Publication.