Cases Required for Studies

From time to time we will post details here of requests of patients to participate in research studies. These are directed to our referring vets. If you are a pet owner and are interested in participating a study you see here, please speak to your vet.

Calling for Great Danes to screen for dilated cardiomyopathy (DCM)

We have funding from the Kennel Club Charitable Trust and the Great Dane Breed Council to screen Great Danes for DCM, by Echocardiography (in dogs of 4 years or older) and Holter monitoring (in dogs over 12 months of age), including cardiac biomarkers. Please contact the cardiology team to discuss whether your Dane or your client’s Great Dane may be a suitable candidate.

Calling for dogs with Atrial Fibrillation (AF)

The Cardiology service are seeking dogs with atrial fibrillation for a prospective study to investigate whether good heart rate control influences quality of life and outcome for dogs. This is a collaboration with former University of Liverpool colleagues at Willows referrals, Solihull (Brigite Pedro) and University of Pennsylvania (Anna Gelzer, Marc Kraus).  There is some limited financial support to cover costs of echocardiography and Holter monitoring during the course of the project, but clients should be able to cover the costs of consultation, other investigations including radiography, blood tests etc. and medications.

Dogs with any underlying cardiac disease are eligible for inclusion, provided they have ECG confirmed atrial fibrillation. They may have congestive heart failure or have isolated atrial fibrillation. They may be symptomatic or asymptomatic.  Exclusion criteria include bradyarrhythmias, pacemaker implanted, known prior treatment with doxorubicin / epirubicin (chemotherapy) and known current systemic disease.  

Owners need to be willing to attend at least every 6 months during the study, but at the beginning of the study, may need to be able to attend a few times to stabilise the heart rate control, which is verified by the Holter monitoring ECG.

Please contact the cardiology service at the University of Liverpool SATH for further information or to discuss potential cases who may benefit from this study.

The study is supported by a grant to Brigite Pedro from the European College of Veterinary Internal Medicine.