M.BioSci. University of Liverpool
Recent publications [here]
I completed my integrated Masters (MBiolSci) studies at the University of Liverpool in 2020. My undergraduate project involved the study of novel myoglobin transcriptional variants in the mouse brain tissue. It is during this project I was enlightened to the importance of hypoxia across various key and pathological processes, most notably its behaviour in cancer. I was then fortunate enough to work at the Chulalongkorn University in Thailand during which I studied a treatment that could potentially reverse replicative senescence. I then moved on to my Masters year where I investigated how the post-translational modification status of HIF-2α affects its ability to induce gene expression. This project piqued my interest of HIF and hypoxia whilst allowing me to gain a great deal of understanding of the functions of HIF in the context of its post-translational modifications.
Currently, I am carrying out a PhD studentship that was awarded to me from The Biotechnology and Biological Sciences Research Council (BBSRC), which will be supervised by Prof. Sonia Rocha and Prof. Claire Eyers. The project will investigate the physiological significance of a relatively unstudied protein called SINHCAF, and how this SINHCAF functionally interacts with HIF and NF-kappaB pathways. In particular, there will be an emphasis on mass spectrometry to examine how the binding partners of SINHCAF affect its function.