Prachi Gupta

Postdoctoral Researcher in the Department of Chemistry

What did you study at A-level (or equivalent) and why did you select those subjects?
At A-level I chose Chemistry because I was fascinated by the idea that everything around us is made of atoms. What intrigued me most was how simply rearranging those atoms could completely change a material’s properties — even the smallest structural difference could transform how a substance behaves. That sense of discovery made Chemistry feel less like a subject and more like a way of understanding the world.

What PhD did you study?
I completed a PhD in Chemistry titled “Synthesis, Characterization and Redox Properties of Expanded Isophlorinoids Containing Six, Seven, Eight, Nine and Ten Heterocyclic Units.”

What inspired you to choose and study your degree subject?
My interest in organic chemistry, especially the behaviour of antiaromatic molecules, inspired me to choose my degree subject. At school, we learned that these molecules are unstable under normal conditions because of their electronic structure. Later, I discovered that extending conjugation could stabilise them, even at ambient conditions.

What fascinated me further was their ability to undergo two-electron redox processes to form stable dications. Seeing purely organic molecules act almost like pseudo-metals opened my eyes to their potential for making chemical processes more efficient and environmentally friendly. That sense of discovery — and the possibility of contributing to greener chemistry — motivated me to study this field.

What key skills did you learn at university?
My degree equipped me with a wide range of scientific and personal skills. I refined my synthetic techniques and built strong expertise in characterisation methods, including crystallography, which revealed how molecules arrange themselves in three-dimensional space. I also gained experience with DFT calculations, which deepened my understanding of molecular behaviour.

Beyond the science, I developed strong communication skills through conference presentations, leadership abilities by training undergraduate students, and organisational skills by helping to run departmental chemistry events. Altogether, university shaped me not only as a scientist but also as a communicator, mentor, and collaborator.

What jobs have you had during your career?
I have worked as a postdoctoral researcher, which allowed me to advance academic research while also mentoring undergraduate and master’s students.

What is your current job and what do you enjoy about it?
I am currently a postdoctoral researcher at the University of Liverpool, and I really enjoy working in academia. Research can be challenging, with new problems to solve almost every day, but investing the time and effort to overcome them is highly rewarding. The satisfaction of generating novel results and contributing to new knowledge is unmatched. I particularly enjoy the process of discovery, as well as the opportunity to mentor and collaborate with students and colleagues.

Do you have an area of expertise?
Yes, I specialise in flow chemistry, with a focus on the synthesis and study of macrocycles and molecular cages. At present, I’m working on porous materials and exploring greener, more efficient ways to produce them using flow chemistry. I enjoy how this research combines the challenge of designing complex molecular structures with the practical goal of making chemical processes more sustainable.

What has been your most exciting project or career role?
My current role excites me the most because it brings together my background in macrocycle chemistry with my passion for green process development, particularly flow chemistry. Working at this interface allows me to expand my knowledge while pursuing the kind of research I want to lead as an independent PI in the future. I also value the chance to mentor students and develop my supervisory skills. For me, the opportunity to learn new techniques while shaping the next generation of researchers makes this role especially rewarding.

What are your top tips for working in your sector?
Stay curious and read widely — not just in your specific field, but also in related areas. Be open to discussions, as solutions often emerge from unexpected conversations. And always maintain a proper journal: detailed notes on experiments, observations, and results are invaluable for progress and problem-solving.

What is the best piece of advice you have been given?
If you ever feel demotivated, look back at yourself a decade ago. Reflecting on your journey and achievements can be a powerful reminder of how far you’ve come.

Any advice you’d like to share?
Always stay honest in your work and in life. If you ever face a dilemma, trust yourself and follow what feels right. Never dwell on regrets — life is a lesson, and every experience provides an opportunity to learn and grow.

Why are you passionate about your subject?
I’ve always been a curious person, full of “what ifs” in the best sense. Research gives me the satisfaction of exploring those questions and finding answers. It has also helped me realise my capabilities and given me a new level of confidence. I particularly enjoy flow chemistry and how it can be applied to almost any type of synthesis, making chemical processes greener and more energy-efficient.

More resources:
Prachi's LinkedIn

Back to: Liverpool Women in Science & Engineering