Photo of Dr Thamir Ismail

Dr Thamir Ismail

Research Associate Molecular & Clinical Cancer Medicine

Publications

2019

S100A4 elevation empowers expression of metastasis effector molecules in human breast cancer (Conference Paper)

Ismail, T. M., Bennett, D., Platt-Higgins, A., Al-Medhity, M., Barraclough, R., & Rudland, P. (2019). S100A4 elevation empowers expression of metastasis effector molecules in human breast cancer. In CLINICAL & EXPERIMENTAL METASTASIS Vol. 36 (pp. 158). Retrieved from http://gateway.webofknowledge.com/

2018

Proteolysis-targeting chimera (PROTAC) compounds to degrade S100A4 and inhibit breast cancer metastasis (Conference Paper)

Du, M., Wang, G., Ismail, T. M., Crick, R., Barraclough, R., Daimark, B. H., . . . Rudland, P. (2018). Proteolysis-targeting chimera (PROTAC) compounds to degrade S100A4 and inhibit breast cancer metastasis. In ANNALS OF ONCOLOGY Vol. 29. Retrieved from http://gateway.webofknowledge.com/

S100P enhances the motility and invasion of human trophoblast cell lines (Journal article)

Tabrizi, M. E. A., Lancaster, T. L., Ismail, T. M., Georgiadou, A., Ganguly, A., Mistry, J. J., . . . Gross, S. R. (2018). S100P enhances the motility and invasion of human trophoblast cell lines. SCIENTIFIC REPORTS, 8. doi:10.1038/s41598-018-29852-2

DOI: 10.1038/s41598-018-29852-2

2017

Activation of tissue plasminogen activator by metastasis-inducing S100P protein (Journal article)

Clarke, C. J., Gross, S. R., Ismail, T. M., Rudland, P. S., Al-Medhtiy, M., Santangeli, M., & Barraclough, R. (2017). Activation of tissue plasminogen activator by metastasis-inducing S100P protein. BIOCHEMICAL JOURNAL, 474, 3227-3240. doi:10.1042/BCJ20170578

DOI: 10.1042/BCJ20170578

Activation of tissue plasminogen activator by S100P protein (Journal article)

Clarke, C. J., Gross, S., Ismail, T. M., Rudland, P. S., Al-Medhtiy, M., Santangeli, M., & Barraclough, B. R. (2017). Activation of tissue plasminogen activator by S100P protein. Biochemical Journal. doi:10.1042/BCJ20170578

DOI: 10.1042/BCJ20170578

2016

S100A4 Elevation Empowers Expression of Metastasis Effector Molecules in Human Breast Cancer. (Journal article)

Ismail, T. M., Bennett, D., Platt-Higgins, A. M., Al-Medhity, M., Barraclough, R., & Rudland, P. S. (2016). S100A4 Elevation Empowers Expression of Metastasis Effector Molecules in Human Breast Cancer.. Cancer research, 77(3), 780-789. doi:10.1158/0008-5472.can-16-1802

DOI: 10.1158/0008-5472.can-16-1802

2012

S100P Dissociates Myosin IIA Filaments and Focal Adhesion Sites to Reduce Cell Adhesion and Enhance Cell Migration (Journal article)

Du, M., Wang, G., Ismail, T. M., Gross, S., Fernig, D. G., Barraclough, R., & Rudland, P. S. (2012). S100P Dissociates Myosin IIA Filaments and Focal Adhesion Sites to Reduce Cell Adhesion and Enhance Cell Migration. JOURNAL OF BIOLOGICAL CHEMISTRY, 287(19), 15330-15344. doi:10.1074/jbc.M112.349787

DOI: 10.1074/jbc.M112.349787

2010

Self-association of Calcium-binding Protein S100A4 and Metastasis (Journal article)

Ismail, T. M., Zhang, S., Fernig, D. G., Gross, S., Martin-Fernandez, M. L., See, V., . . . Barraclough, R. (2010). Self-association of Calcium-binding Protein S100A4 and Metastasis. JOURNAL OF BIOLOGICAL CHEMISTRY, 285(2), 914-922. doi:10.1074/jbc.M109.010892

DOI: 10.1074/jbc.M109.010892

2008

The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis (Journal article)

Ismail, T. M., Fernig, D. G., Rudland, P. S., Terry, C. J., Wang, G., & Barraclough, R. (2008). The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis. CARCINOGENESIS, 29(12), 2259-2266. doi:10.1093/carcin/bgn217

DOI: 10.1093/carcin/bgn217

2003

Regulation of dinucleoside polyphosphate pools by the YgdP and ApaH hydrolases is essential for the ability of Salmonella enterica serovar typhimurium to invade cultured mammalian cells. (Journal article)

Ismail, T. M., Hart, C. A., & McLennan, A. G. (2003). Regulation of dinucleoside polyphosphate pools by the YgdP and ApaH hydrolases is essential for the ability of Salmonella enterica serovar typhimurium to invade cultured mammalian cells.. The Journal of biological chemistry, 278(35), 32602-32607. doi:10.1074/jbc.m305994200

DOI: 10.1074/jbc.m305994200

2001

Functional Analysis of six novel ORFs on the left arm of Chromosome XII of Sacharomyses cerevisiae reveals three of them responding to S- starvation (Journal article)

Zhang, N., Merlotti, C., Wu, J., Ismail, T., & El-Moghazy, A. -N. (2001). Functional Analysis of six novel ORFs on the left arm of Chromosome XII of Sacharomyses cerevisiae reveals three of them responding to S- starvation. Yeast, 18(4), 325-334.

2000

Functional analysis of eight open reading frames on chromosomes XII and XIV of Saccharomyces cerevisiae (Journal article)

Khan, S. A., Zhang, N., Ismail, T., El-Moghazy, A. -N., Butt, A., Wu, J., . . . Oliver, S. G. (2000). Functional analysis of eight open reading frames on chromosomes XII and XIV of Saccharomyces cerevisiae. Yeast, 16, 1457-1468.

Functional analysis of six novel ORFs on the left arm of Chromosome XII in Saccharomyces cerevisiae reveals two essential genes, one of which is under cell-cycle control (Journal article)

El-Moghazy, A. -N., Zhang, N., Ismail, T., Wu, J., Butt, A., Khan, S. A., . . . Oliver, S. G. (2000). Functional analysis of six novel ORFs on the left arm of Chromosome XII in Saccharomyces cerevisiae reveals two essential genes, one of which is under cell-cycle control. Yeast, 16, 277-288.

1999

Disruption of Six Novel ORFs on the Left Arm of Chromosome XII Reveals One Gene Essential for Vegetative Growth of Saccharomyces cerevisiae (Journal article)

Zhang, N., Ismail, T., Wu, J., Woodwark, K. C., Gardner, D. C. J., Walmsley, R. M., & Oliver, S. G. (1999). Disruption of Six Novel ORFs on the Left Arm of Chromosome XII Reveals One Gene Essential for Vegetative Growth of Saccharomyces cerevisiae. Yeast, 15, 1287-1296.

1986

Alteration in serological and pyocin typing patterns of Pseudomonas aeruginosa accompanying acquired resistance to gentamycin (Journal article)

Al-Ani, F. Y., Ismail, T. M., & Al Mudhaffar, S. A. (1986). Alteration in serological and pyocin typing patterns of Pseudomonas aeruginosa accompanying acquired resistance to gentamycin. Journal of University Kuwait, 13, 193-196.