Neil Kad

New Insights into Complex Mechanisms: a Single Molecule Journey across a Tightrope

1:00pm - 2:00pm / Monday 14th October 2019 / Venue: LT1 Life Sciences Building
Type: Seminar / Category: Research / Series: GSTT Seminar Series
  • Suitable for: Those interested in Genomes, Systems and Therapeutic Targeting
  • Admission: Free
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Speaker: Neil Kad (University of Kent)

In this talk Dr Kad will explore the complex mechanisms of DNA repair and muscle activation using a single molecule method that employs the use of nanowires. These structures of either DNA or actin, are used as substrates in a biophysical exploration of molecular cooperativity. By fluorescently tagging these proteins with quantum dots and using imaging, complex stories of how repair proteins find damage on DNA; or how the most abundantly mutated protein in cardiomyopathy, myosin binding protein-C, modulates contraction. Finally, using optical tweezers, Dr Kad will strum the world's smallest guitar!