New Insights into Complex Mechanisms: a Single Molecule Journey across a Tightrope

1:00pm - 2:00pm / Monday 14th October 2019 / Venue: LT1 Life Sciences Building
Type: Seminar / Category: Research / Series: GSTT Seminar Series
  • Suitable for: Those interested in Genomes, Systems and Therapeutic Targeting
  • Admission: Free
  • Add this event to my calendar
    (?)

    When you click on "Add this event to my calendar" your browser will download an ics file.

    Microsoft Outlook: Download the file, then you may be able to click on "Save & Close" to save it to your calendar. If that doesn't work go into Outlook, click on the File tab, then on Open, then Import. Select "Import an iCalendar (.ic or vCalendar file (.vcs)" then click on Next. Find the .ics file and click on OK.

    Google Calendar: download the file, then go into your calendar. On the right where it says "Other calendars" click on the arrow icon and then click on Import calendar. Click on Browse and select the .ics file, then click on Import.

    Apple Calendar: download the file, then you can either drag it to Calendar or import the file by going to File > Import > Import and choosing the .ics file.

Speaker: Neil Kad (University of Kent)

In this talk Dr Kad will explore the complex mechanisms of DNA repair and muscle activation using a single molecule method that employs the use of nanowires. These structures of either DNA or actin, are used as substrates in a biophysical exploration of molecular cooperativity. By fluorescently tagging these proteins with quantum dots and using imaging, complex stories of how repair proteins find damage on DNA; or how the most abundantly mutated protein in cardiomyopathy, myosin binding protein-C, modulates contraction. Finally, using optical tweezers, Dr Kad will strum the world's smallest guitar!