CANCELLED Orphan Enzymes as a Window into Untapped Bacterial Physiology

4:00pm - 5:00pm / Tuesday 3rd December 2019 / Venue: LT2 Life Sciences Building
Type: Seminar / Category: Research / Series: BEEM Seminar
  • Suitable for: Staff and students interested in Behaviour, Evolution, Ecology and Microbiology
  • Admission: Free
  • Add this event to my calendar

    When you click on "Add this event to my calendar" your browser will download an ics file.

    Microsoft Outlook: Download the file, then you may be able to click on "Save & Close" to save it to your calendar. If that doesn't work go into Outlook, click on the File tab, then on Open, then Import. Select "Import an iCalendar (.ic or vCalendar file (.vcs)" then click on Next. Find the .ics file and click on OK.

    Google Calendar: download the file, then go into your calendar. On the right where it says "Other calendars" click on the arrow icon and then click on Import calendar. Click on Browse and select the .ics file, then click on Import.

    Apple Calendar: download the file, then you can either drag it to Calendar or import the file by going to File > Import > Import and choosing the .ics file.

Speaker: Luiz de Carvalho (The Crick Institute)

Despite advances in genomics and bioinformatics in the last two decades, approximately half of bacterial genomes remain unannotated. These proteins bear little to no similarity with proteins which have been characterised. This vast amount of unknown biological space is halting our understanding of fundamental aspects of microbiology and slowing down antibiotic drug discovery. In this seminar Luiz will demonstrate the power of multidisciplinary approaches centred on metabolomics, to identify de novo functions to annotated enzymes from the human pathogen Mycobacterium tuberculosis.