Professor Cosimo De Bari, Aberdeen. 'The Synovium as a stem cell niche for joint repair.' Host: George Bou-Gharios
12:45pm - 1:45pm /
Friday 1st September 2017
/ Venue: G12 - G15, Ground floor, William Henry Duncan Apex Building
- 0151 794 9003
- Brenda Smith
- Suitable for: Staff and students
- Admission: Free to staff and students
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Brief Biography
Professor Cosimo De Bari is a clinically active rheumatologist with expertise in musculoskeletal regenerative medicine and joint pathophysiology.
Cosimo graduated in Medicine (summa cum laude) from the University of Bari (Italy), where he underwent specialist training in Rheumatology. He obtained his PhD from the University of Leuven (Belgium). In 2003 Cosimo moved to King's College London, where in 2005 he was awarded an MRC Fellowship. Since 2007 Cosimo holds a chair in Translational Medicine at the University of Aberdeen. He is founder and director of the Aberdeen Centre for Musculoskeletal Health, deputy director of the Arthritis Research UK Tissue Engineering Centre and of the EULAR Centre of Excellence in Rheumatology at Aberdeen.
Osteoarthritis (OA) is the most common joint disease, affecting ~9 million people in the UK. OA causes progressive breakdown of articular cartilage and bone, leading to joint failure. Current treatment options are limited to symptom relief with pain-killers and to prosthetic joint replacement in end-stage disease.
Cell therapy is an attractive approach to repair OA joints. Our work indicates that the adult synovium harbours a population of mesenchymal stromal/stem cells (MSCs) that can repair cartilage after injury and have joint morphogenetic ability, i.e. the ability to orchestrate the process of joint formation. The long-term prospect of our research is to devise ways to target the endogenous MSCs to maintain healthy joints, prevent/delay OA, and restore joint homeostasis.
Professor Cosimo De Bari is a clinically active rheumatologist with expertise in musculoskeletal regenerative medicine and joint pathophysiology.
Cosimo graduated in Medicine (summa cum laude) from the University of Bari (Italy), where he underwent specialist training in Rheumatology. He obtained his PhD from the University of Leuven (Belgium). In 2003 Cosimo moved to King's College London, where in 2005 he was awarded an MRC Fellowship. Since 2007 Cosimo holds a chair in Translational Medicine at the University of Aberdeen. He is founder and director of the Aberdeen Centre for Musculoskeletal Health, deputy director of the Arthritis Research UK Tissue Engineering Centre and of the EULAR Centre of Excellence in Rheumatology at Aberdeen.
Osteoarthritis (OA) is the most common joint disease, affecting ~9 million people in the UK. OA causes progressive breakdown of articular cartilage and bone, leading to joint failure. Current treatment options are limited to symptom relief with pain-killers and to prosthetic joint replacement in end-stage disease.
Cell therapy is an attractive approach to repair OA joints. Our work indicates that the adult synovium harbours a population of mesenchymal stromal/stem cells (MSCs) that can repair cartilage after injury and have joint morphogenetic ability, i.e. the ability to orchestrate the process of joint formation. The long-term prospect of our research is to devise ways to target the endogenous MSCs to maintain healthy joints, prevent/delay OA, and restore joint homeostasis.