GSTT SEMINAR: Dr Chiu Fan Lee, Imperial College London - Title: 'Protein amyloid self-assembly: Thermodynamics, kinetics and pathogenesis'
1:00pm - 2:00pm /
Monday 3rd October 2016
/ Venue: Lecture Theatre 1 Life Sciences Building
- Jill Madine
- Admission: Free
Add this event to my calendar
Click on "Create a calendar file" and your browser will download a .ics file for this event.
Microsoft Outlook: Download the file, double-click it to open it in Outlook, then click on "Save & Close" to save it to your calendar. If that doesn't work go into Outlook, click on the File tab, then on Open & Export, then Open Calendar. Select your .ics file then click on "Save & Close".
Google Calendar: download the file, then go into your calendar. On the left where it says "Other calendars" click on the arrow icon and then click on Import calendar. Click on Browse and select the .ics file, then click on Import.
Apple Calendar: The file may open automatically with an option to save it to your calendar. If not, download the file, then you can either drag it to Calendar or import the file by going to File >Import > Import and choosing the .ics file.
Amyloid fibrils are linear aggregates of proteins rich in beta-sheet structure. Amyloids are intimately related to numerous human diseases including Alzheimer’s, Parkinson’s and type II diabetes. In vitro experiments have revealed universal properties of the amyloid self-assembly process. In this talk, I will first focus on the thermodynamic and kinetic aspects of a generic amyloid forming system. I will then discuss the potential importance of interfacial effects, phase separation and gelation in amyloid pathogenesis.
If anyone would like to meet the speaker please contact Jill Madine.
If anyone would like to meet the speaker please contact Jill Madine.