Dr Aditi Borkar - 'Cryo-OrbiSIMS enables integrative modelling of native RNA structures during cellular health and disease'
12:00pm - 1:00pm /
Wednesday 15th April 2026
/ Venue: Physiology Seminar Room Nuffield Wing
Type: Seminar /
Category: Department
- ISMIB Seminar Team
- Suitable for: Everyone
- Admission: Free for all
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Dr Aditi Borkaris an Assistant Professor at the University of Nottingham. Her research focuses on high-resolution studies of RNA-mediated disease pathologies in viral infections and rare genetic disorders.
In this seminar, Dr Borkar will present their latest development of cryogenic OrbiSIMS, a solid-state mass spectrometry imaging technique, to overcome longstanding challenges in RNA structural biology. These results open exciting new possibilities for structural analysis of previously intractable RNA systems, with direct relevance to ISMIB's interests in molecular mechanisms of disease and the rational development of novel therapeutics.
Keywords: RNA, structural biology, viruses, cryo-OrbiSIMS, mass spectrometry imaging, modelling, biophysics.
In this seminar, Dr Borkar will present their latest development of cryogenic OrbiSIMS, a solid-state mass spectrometry imaging technique, to overcome longstanding challenges in RNA structural biology. These results open exciting new possibilities for structural analysis of previously intractable RNA systems, with direct relevance to ISMIB's interests in molecular mechanisms of disease and the rational development of novel therapeutics.
Keywords: RNA, structural biology, viruses, cryo-OrbiSIMS, mass spectrometry imaging, modelling, biophysics.