Dr Shijie Cai, University of Oxford - 'Interconnections between metabolism and inflammation in the colorectal tumour microenvironment'
1:00pm - 2:00pm /
Thursday 12th March 2026
/ Venue: Physiology seminar room Nuffield Wing
Type: Seminar /
Category: Research
/ Series: Institute of Systems, Molecular and Integrative Biology
- ISMIB Seminar Team
- Admission: Free, no registration required.
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Shijie Cai received his Bachelor of Medicine from Tongji Medical University, China, and began his clinical career as a Paediatrician specialising in paediatric respiratory infectious diseases at Fujian Women and Children’s Hospital. He later earned an MPhil in Medical Microbiology from the University of Liverpool and served as a Clinical Research Fellow at Alder Hey Children’s Hospital. He is a UK-qualified Clinical Virologist.
He completed his PhD at the University of Cambridge, where he developed herpes simplex viral vectors for gene transfer targeting the nervous system. Following this, he undertook postdoctoral research in the Department of Cardiovascular Medicine at the University of Oxford.
In 2007, he established his independent research programme as a Principal Investigator in the Department of Clinical Pharmacology at Oxford, where he elucidated a novel mechanism by which biopterin metabolism regulates angiogenesis and myofibroblast differentiation in breast cancer.
Currently, he leads a research group focused on the oncometabolic crosstalk between stromal fibroblasts, immune cells, and tumour cells in gastrointestinal cancers, aiming to uncover therapeutic vulnerabilities and advance translational cancer medicine.
All welcome.
He completed his PhD at the University of Cambridge, where he developed herpes simplex viral vectors for gene transfer targeting the nervous system. Following this, he undertook postdoctoral research in the Department of Cardiovascular Medicine at the University of Oxford.
In 2007, he established his independent research programme as a Principal Investigator in the Department of Clinical Pharmacology at Oxford, where he elucidated a novel mechanism by which biopterin metabolism regulates angiogenesis and myofibroblast differentiation in breast cancer.
Currently, he leads a research group focused on the oncometabolic crosstalk between stromal fibroblasts, immune cells, and tumour cells in gastrointestinal cancers, aiming to uncover therapeutic vulnerabilities and advance translational cancer medicine.
All welcome.